ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NFKMLMMI_00001 8.24e-250 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NFKMLMMI_00002 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NFKMLMMI_00003 4.34e-201 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NFKMLMMI_00004 1.49e-115 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NFKMLMMI_00005 8.23e-269 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NFKMLMMI_00006 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NFKMLMMI_00007 1.3e-180 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NFKMLMMI_00008 1.15e-260 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NFKMLMMI_00009 1.61e-214 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NFKMLMMI_00010 1.26e-60 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NFKMLMMI_00012 1.16e-118 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NFKMLMMI_00013 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NFKMLMMI_00014 6.61e-232 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NFKMLMMI_00015 3.4e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
NFKMLMMI_00016 7.88e-244 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NFKMLMMI_00017 9.18e-290 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NFKMLMMI_00018 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NFKMLMMI_00019 3.7e-80 yrzE - - S - - - Protein of unknown function (DUF3792)
NFKMLMMI_00020 1.16e-133 yrbG - - S - - - membrane
NFKMLMMI_00021 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFKMLMMI_00022 2.26e-64 yrzD - - S - - - Post-transcriptional regulator
NFKMLMMI_00023 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NFKMLMMI_00024 3.74e-104 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NFKMLMMI_00025 7.18e-59 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NFKMLMMI_00026 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NFKMLMMI_00027 1.71e-116 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NFKMLMMI_00028 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NFKMLMMI_00029 4.07e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NFKMLMMI_00030 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NFKMLMMI_00033 7.9e-306 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NFKMLMMI_00034 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NFKMLMMI_00035 1.68e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NFKMLMMI_00036 4.18e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NFKMLMMI_00037 3.74e-83 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_00038 2.35e-266 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NFKMLMMI_00039 8.02e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NFKMLMMI_00040 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
NFKMLMMI_00041 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NFKMLMMI_00042 9e-101 yrrD - - S - - - protein conserved in bacteria
NFKMLMMI_00043 8.4e-42 yrzR - - - - - - -
NFKMLMMI_00044 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
NFKMLMMI_00045 1.41e-134 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NFKMLMMI_00046 4.6e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NFKMLMMI_00047 5.82e-185 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NFKMLMMI_00048 1.43e-164 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NFKMLMMI_00049 4.09e-231 yrrI - - S - - - AI-2E family transporter
NFKMLMMI_00050 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NFKMLMMI_00051 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
NFKMLMMI_00052 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NFKMLMMI_00053 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
NFKMLMMI_00054 6.36e-256 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NFKMLMMI_00055 4.49e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NFKMLMMI_00056 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NFKMLMMI_00057 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NFKMLMMI_00058 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NFKMLMMI_00059 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NFKMLMMI_00060 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NFKMLMMI_00061 8.77e-104 yrrS - - S - - - Protein of unknown function (DUF1510)
NFKMLMMI_00062 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
NFKMLMMI_00063 1.4e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NFKMLMMI_00064 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NFKMLMMI_00065 2.28e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NFKMLMMI_00066 7.59e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NFKMLMMI_00067 1.35e-46 yrhC - - S - - - YrhC-like protein
NFKMLMMI_00068 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
NFKMLMMI_00069 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NFKMLMMI_00070 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NFKMLMMI_00071 4.62e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NFKMLMMI_00072 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NFKMLMMI_00073 3.67e-120 yrhH - - Q - - - methyltransferase
NFKMLMMI_00074 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NFKMLMMI_00075 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NFKMLMMI_00076 1.32e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_00077 5.33e-211 yybE - - K - - - Transcriptional regulator
NFKMLMMI_00078 1.88e-106 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NFKMLMMI_00079 9.54e-229 romA - - S - - - Beta-lactamase superfamily domain
NFKMLMMI_00080 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NFKMLMMI_00081 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_00082 9.08e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NFKMLMMI_00083 2.38e-167 - - - K - - - Helix-turn-helix domain, rpiR family
NFKMLMMI_00084 7.33e-67 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NFKMLMMI_00085 5.2e-93 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NFKMLMMI_00086 1.14e-187 supH - - S - - - hydrolase
NFKMLMMI_00088 2.76e-120 - - - S - - - DinB family
NFKMLMMI_00089 6.08e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NFKMLMMI_00090 5.34e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_00091 1.84e-126 yqaC - - F - - - adenylate kinase activity
NFKMLMMI_00093 3.5e-47 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NFKMLMMI_00094 1.02e-79 - - - K - - - Transcriptional regulator PadR-like family
NFKMLMMI_00095 1.25e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
NFKMLMMI_00096 6.77e-21 xkdG - - S - - - Phage capsid family
NFKMLMMI_00097 1.29e-89 - - - K - - - MerR family transcriptional regulator
NFKMLMMI_00098 1.23e-174 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
NFKMLMMI_00099 8.72e-34 xkdR - - S - - - Protein of unknown function (DUF2577)
NFKMLMMI_00100 8.03e-141 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NFKMLMMI_00101 8.55e-19 xkdS - - S - - - Protein of unknown function (DUF2634)
NFKMLMMI_00103 5.49e-13 - - - S - - - SMI1-KNR4 cell-wall
NFKMLMMI_00107 1.39e-24 - - - - - - - -
NFKMLMMI_00108 2.68e-135 lin0465 - - S - - - DJ-1/PfpI family
NFKMLMMI_00109 1.28e-206 - - - K ko:K13572 - ko00000,ko03051 HTH domain
NFKMLMMI_00111 2.82e-142 mchB - - Q ko:K12240 ko01053,map01053 ko00000,ko00001,ko01008 Thioesterase involved in non-ribosomal peptide biosynthesis
NFKMLMMI_00112 5.94e-257 glyA_1 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NFKMLMMI_00113 4.19e-152 - - - S - - - Winged helix DNA-binding domain
NFKMLMMI_00114 0.0 - - - Q - - - AMP-binding enzyme C-terminal domain
NFKMLMMI_00115 0.0 - - - Q - - - AMP-binding enzyme C-terminal domain
NFKMLMMI_00116 4.17e-221 - 6.2.1.30 - H ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 ko00000,ko00001,ko01000 phenylacetate-CoA ligase activity
NFKMLMMI_00117 1.71e-224 - 4.1.3.27, 4.2.99.21, 5.4.4.2 - EH ko:K01657,ko:K04781 ko00400,ko00405,ko01053,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01053,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I domain protein
NFKMLMMI_00118 2.93e-98 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 TIGRFAM glutamine amidotransferase of anthranilate synthase
NFKMLMMI_00119 1.78e-199 smvA - - EGP ko:K08167 - ko00000,ko00002,ko01504,ko02000 Major facilitator superfamily
NFKMLMMI_00120 6.3e-11 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
NFKMLMMI_00121 1.18e-50 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NFKMLMMI_00122 1.46e-194 - - - L - - - AAA ATPase domain
NFKMLMMI_00123 1.82e-17 - - - L ko:K06400 - ko00000 Recombinase
NFKMLMMI_00124 1.01e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFKMLMMI_00125 3.32e-124 xkdA - - E - - - IrrE N-terminal-like domain
NFKMLMMI_00128 1.25e-74 - - - K - - - sequence-specific DNA binding
NFKMLMMI_00129 2.23e-47 - - - K - - - Helix-turn-helix XRE-family like proteins
NFKMLMMI_00131 1.04e-133 - - - - - - - -
NFKMLMMI_00135 1.21e-215 yqaJ - - L - - - YqaJ-like viral recombinase domain
NFKMLMMI_00136 1.38e-192 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NFKMLMMI_00137 4.84e-148 yqaL - - L - - - DnaD domain protein
NFKMLMMI_00138 6.14e-208 yqaM - - L - - - IstB-like ATP binding protein
NFKMLMMI_00140 1.82e-93 rusA - - L - - - Endodeoxyribonuclease RusA
NFKMLMMI_00141 2.05e-42 yqaO - - S - - - Phage-like element PBSX protein XtrA
NFKMLMMI_00142 4.33e-70 - - - S - - - Psort location Cytoplasmic, score
NFKMLMMI_00143 2.06e-61 - - - S - - - Beta protein
NFKMLMMI_00144 4.9e-100 yqaQ - - L - - - Transposase
NFKMLMMI_00148 3.38e-70 - - - - - - - -
NFKMLMMI_00149 5.01e-110 yqaS - - L - - - DNA packaging
NFKMLMMI_00150 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
NFKMLMMI_00151 0.0 yqbA - - S - - - portal protein
NFKMLMMI_00152 2.42e-190 - - - S - - - Phage Mu protein F like protein
NFKMLMMI_00154 1.43e-165 yqbD - - L - - - Putative phage serine protease XkdF
NFKMLMMI_00155 1.86e-215 xkdG - - S - - - Phage capsid family
NFKMLMMI_00156 5.19e-61 - - - S - - - YqbF, hypothetical protein domain
NFKMLMMI_00157 1.01e-87 - - - S - - - Protein of unknown function (DUF3199)
NFKMLMMI_00158 1.61e-81 yqbH - - S - - - Domain of unknown function (DUF3599)
NFKMLMMI_00159 2.66e-113 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NFKMLMMI_00160 3e-98 yqbJ - - - - - - -
NFKMLMMI_00161 2.44e-34 - - - - - - - -
NFKMLMMI_00162 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
NFKMLMMI_00163 2.02e-97 xkdM - - S - - - Phage tail tube protein
NFKMLMMI_00164 6.07e-247 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM Reverse transcriptase (RNA-dependent DNA polymerase)
NFKMLMMI_00165 6.02e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NFKMLMMI_00166 0.0 xkdO - - L - - - Transglycosylase SLT domain
NFKMLMMI_00167 4.43e-154 xkdP - - S - - - Lysin motif
NFKMLMMI_00168 4.44e-226 xkdQ - - G - - - NLP P60 protein
NFKMLMMI_00169 9.93e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
NFKMLMMI_00170 7.71e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
NFKMLMMI_00171 3.45e-241 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NFKMLMMI_00172 5.52e-126 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NFKMLMMI_00173 7.09e-53 - - - - - - - -
NFKMLMMI_00174 1.33e-279 - - - - - - - -
NFKMLMMI_00175 8.96e-68 xkdW - - S - - - XkdW protein
NFKMLMMI_00176 8.73e-29 - - - - - - - -
NFKMLMMI_00177 1.15e-202 xepA - - - - - - -
NFKMLMMI_00178 4.84e-88 - - - S - - - Bacteriophage holin family
NFKMLMMI_00179 6.73e-178 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NFKMLMMI_00181 6.31e-79 - - - - - - - -
NFKMLMMI_00184 9.89e-288 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NFKMLMMI_00186 1.49e-78 - - - S - - - Tetratricopeptide repeat
NFKMLMMI_00187 9.16e-26 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NFKMLMMI_00189 4.11e-134 yrkC - - G - - - Cupin domain
NFKMLMMI_00190 3.21e-11 yrkD - - S - - - protein conserved in bacteria
NFKMLMMI_00191 0.0 - - - L ko:K06400 - ko00000 Recombinase
NFKMLMMI_00192 3.66e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFKMLMMI_00193 2.47e-274 - - - EGP - - - Transmembrane secretion effector
NFKMLMMI_00194 9.72e-08 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NFKMLMMI_00196 3.41e-137 yqeD - - S - - - SNARE associated Golgi protein
NFKMLMMI_00197 3.16e-178 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NFKMLMMI_00198 3.99e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NFKMLMMI_00200 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NFKMLMMI_00201 1.87e-270 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NFKMLMMI_00202 2.83e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NFKMLMMI_00203 1.49e-59 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NFKMLMMI_00204 1.38e-138 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NFKMLMMI_00205 3.25e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NFKMLMMI_00206 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NFKMLMMI_00207 1.98e-177 yqeM - - Q - - - Methyltransferase
NFKMLMMI_00208 1.14e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NFKMLMMI_00209 1.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NFKMLMMI_00210 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NFKMLMMI_00211 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NFKMLMMI_00212 6.09e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NFKMLMMI_00213 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NFKMLMMI_00214 1.02e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NFKMLMMI_00215 2.6e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NFKMLMMI_00216 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
NFKMLMMI_00217 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NFKMLMMI_00218 3.95e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NFKMLMMI_00219 1.11e-239 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NFKMLMMI_00220 1.99e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NFKMLMMI_00221 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NFKMLMMI_00222 6.71e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NFKMLMMI_00223 1.27e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NFKMLMMI_00224 3.96e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NFKMLMMI_00225 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NFKMLMMI_00226 1.99e-194 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NFKMLMMI_00227 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NFKMLMMI_00228 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NFKMLMMI_00229 3.91e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NFKMLMMI_00230 1.22e-186 yqfA - - S - - - UPF0365 protein
NFKMLMMI_00231 2.58e-48 yqfB - - - - - - -
NFKMLMMI_00232 3.57e-61 yqfC - - S - - - sporulation protein YqfC
NFKMLMMI_00233 3.96e-273 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NFKMLMMI_00234 4.78e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NFKMLMMI_00235 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NFKMLMMI_00236 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NFKMLMMI_00237 8.76e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NFKMLMMI_00238 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NFKMLMMI_00239 2.86e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NFKMLMMI_00240 6e-24 - - - S - - - YqzL-like protein
NFKMLMMI_00241 2.31e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NFKMLMMI_00242 2.03e-220 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NFKMLMMI_00243 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NFKMLMMI_00244 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NFKMLMMI_00245 2.6e-240 yuxJ - - EGP - - - Major facilitator superfamily
NFKMLMMI_00246 7.29e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NFKMLMMI_00247 4.14e-81 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NFKMLMMI_00248 9.1e-83 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_00249 1.57e-173 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_00250 1.89e-276 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NFKMLMMI_00251 3.95e-51 yugE - - S - - - Domain of unknown function (DUF1871)
NFKMLMMI_00252 3.41e-192 yugF - - I - - - Hydrolase
NFKMLMMI_00253 1.53e-108 alaR - - K - - - Transcriptional regulator
NFKMLMMI_00254 2.28e-264 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NFKMLMMI_00255 8.3e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NFKMLMMI_00256 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NFKMLMMI_00257 7.5e-283 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NFKMLMMI_00258 8.85e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NFKMLMMI_00259 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NFKMLMMI_00261 4.57e-90 yugN - - S - - - YugN-like family
NFKMLMMI_00262 8.97e-227 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NFKMLMMI_00263 2.98e-36 mstX - - S - - - Membrane-integrating protein Mistic
NFKMLMMI_00264 3.56e-22 - - - - - - - -
NFKMLMMI_00265 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NFKMLMMI_00266 1.82e-293 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NFKMLMMI_00267 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NFKMLMMI_00268 5.54e-236 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NFKMLMMI_00269 1.82e-52 - - - - - - - -
NFKMLMMI_00270 1.68e-174 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NFKMLMMI_00271 4.49e-285 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NFKMLMMI_00272 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NFKMLMMI_00273 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NFKMLMMI_00274 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NFKMLMMI_00275 4.02e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NFKMLMMI_00276 4.84e-231 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NFKMLMMI_00277 2.73e-248 yubA - - S - - - transporter activity
NFKMLMMI_00278 7.33e-184 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NFKMLMMI_00280 7.36e-20 - - - - - - - -
NFKMLMMI_00281 2.15e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
NFKMLMMI_00284 2.17e-57 yjcN - - - - - - -
NFKMLMMI_00285 2.36e-47 - - - G - - - Cupin
NFKMLMMI_00286 6.24e-268 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NFKMLMMI_00287 2.27e-185 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NFKMLMMI_00288 1.97e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NFKMLMMI_00289 4.6e-119 yuaB - - - - - - -
NFKMLMMI_00290 9.65e-119 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NFKMLMMI_00291 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NFKMLMMI_00292 9.64e-288 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NFKMLMMI_00293 1.21e-134 - - - S - - - MOSC domain
NFKMLMMI_00294 1.42e-102 yuaE - - S - - - DinB superfamily
NFKMLMMI_00295 1.72e-103 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NFKMLMMI_00296 1.38e-273 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NFKMLMMI_00297 3.55e-118 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NFKMLMMI_00298 1.2e-147 yoxB - - - - - - -
NFKMLMMI_00299 1.23e-49 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NFKMLMMI_00300 4.03e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NFKMLMMI_00301 6.69e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NFKMLMMI_00302 5.78e-173 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NFKMLMMI_00303 3.37e-251 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NFKMLMMI_00304 7.74e-201 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_00305 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NFKMLMMI_00306 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NFKMLMMI_00307 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NFKMLMMI_00308 1.91e-66 - - - K - - - Helix-turn-helix domain
NFKMLMMI_00309 6.45e-238 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
NFKMLMMI_00310 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NFKMLMMI_00311 7.83e-46 yoeD - - G - - - Helix-turn-helix domain
NFKMLMMI_00313 8.33e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NFKMLMMI_00314 1.31e-305 yoeA - - V - - - MATE efflux family protein
NFKMLMMI_00315 1.56e-229 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NFKMLMMI_00316 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NFKMLMMI_00317 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NFKMLMMI_00318 1.51e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NFKMLMMI_00319 9.38e-58 yneR - - S - - - Belongs to the HesB IscA family
NFKMLMMI_00320 5.95e-65 yneQ - - - - - - -
NFKMLMMI_00321 8.11e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NFKMLMMI_00322 4.08e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NFKMLMMI_00324 4.36e-114 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NFKMLMMI_00325 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NFKMLMMI_00326 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NFKMLMMI_00327 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NFKMLMMI_00328 2.64e-77 cotM - - O ko:K06335 - ko00000 Spore coat protein
NFKMLMMI_00329 4.28e-92 yneK - - S - - - Protein of unknown function (DUF2621)
NFKMLMMI_00330 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NFKMLMMI_00331 4.11e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NFKMLMMI_00332 1.38e-158 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NFKMLMMI_00333 8.06e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
NFKMLMMI_00334 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NFKMLMMI_00335 3.48e-103 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NFKMLMMI_00336 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NFKMLMMI_00337 2.33e-43 ynzC - - S - - - UPF0291 protein
NFKMLMMI_00338 4.8e-141 yneB - - L - - - resolvase
NFKMLMMI_00339 4.8e-66 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NFKMLMMI_00340 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NFKMLMMI_00342 2.23e-86 yndM - - S - - - Protein of unknown function (DUF2512)
NFKMLMMI_00343 4.95e-182 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
NFKMLMMI_00344 4.12e-10 - - - - - - - -
NFKMLMMI_00345 2.53e-162 yndL - - S - - - Replication protein
NFKMLMMI_00346 9.69e-99 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NFKMLMMI_00347 1.33e-43 - - - S - - - TM2 domain
NFKMLMMI_00348 0.0 yobO - - M - - - Pectate lyase superfamily protein
NFKMLMMI_00350 1.97e-119 yvgO - - - - - - -
NFKMLMMI_00351 9.32e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NFKMLMMI_00352 3.2e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
NFKMLMMI_00353 2.59e-72 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFKMLMMI_00354 1.19e-74 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NFKMLMMI_00355 6.53e-290 gerKC - - S ko:K06297 - ko00000 spore germination
NFKMLMMI_00356 5.7e-243 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NFKMLMMI_00357 8.5e-316 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFKMLMMI_00358 2.47e-117 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFKMLMMI_00359 2.27e-176 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NFKMLMMI_00360 1.22e-147 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NFKMLMMI_00361 4.6e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_00362 7.36e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NFKMLMMI_00363 1.72e-303 yxeQ - - S - - - MmgE/PrpD family
NFKMLMMI_00364 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NFKMLMMI_00365 4.84e-300 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NFKMLMMI_00366 2.5e-162 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_00367 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
NFKMLMMI_00368 4.37e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NFKMLMMI_00371 1.28e-315 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NFKMLMMI_00372 1.06e-208 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_00373 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_00374 1.55e-173 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_00375 1.67e-220 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NFKMLMMI_00376 3.99e-313 ycnB - - EGP - - - the major facilitator superfamily
NFKMLMMI_00377 4.78e-192 ycnC - - K - - - Transcriptional regulator
NFKMLMMI_00378 2.68e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
NFKMLMMI_00379 2.79e-59 ycnE - - S - - - Monooxygenase
NFKMLMMI_00380 2.56e-66 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NFKMLMMI_00381 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFKMLMMI_00382 2.59e-279 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NFKMLMMI_00383 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NFKMLMMI_00384 3.93e-189 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NFKMLMMI_00385 1.82e-181 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_00386 6.58e-128 ycnI - - S - - - protein conserved in bacteria
NFKMLMMI_00387 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NFKMLMMI_00388 1.15e-135 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NFKMLMMI_00389 2.18e-69 - - - - - - - -
NFKMLMMI_00390 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NFKMLMMI_00391 1.96e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NFKMLMMI_00392 2.79e-255 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NFKMLMMI_00393 4.09e-78 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NFKMLMMI_00395 2.59e-175 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NFKMLMMI_00396 1.66e-169 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NFKMLMMI_00397 2.33e-265 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NFKMLMMI_00398 7.99e-182 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NFKMLMMI_00399 1.75e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NFKMLMMI_00400 1.09e-227 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NFKMLMMI_00401 2.47e-162 kipR - - K - - - Transcriptional regulator
NFKMLMMI_00402 1.97e-143 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NFKMLMMI_00404 2.73e-71 yczJ - - S - - - biosynthesis
NFKMLMMI_00405 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NFKMLMMI_00406 1.53e-213 ycsN - - S - - - Oxidoreductase
NFKMLMMI_00407 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NFKMLMMI_00408 0.0 ydaB - - IQ - - - acyl-CoA ligase
NFKMLMMI_00409 2.64e-196 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_00410 1.08e-122 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NFKMLMMI_00411 1.58e-146 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NFKMLMMI_00412 4.32e-100 ydaG - - S - - - general stress protein
NFKMLMMI_00413 9.89e-174 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NFKMLMMI_00414 2.67e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NFKMLMMI_00415 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NFKMLMMI_00416 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NFKMLMMI_00417 7.77e-240 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NFKMLMMI_00418 4.73e-183 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
NFKMLMMI_00419 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
NFKMLMMI_00420 1.25e-300 ydaM - - M - - - Glycosyl transferase family group 2
NFKMLMMI_00421 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
NFKMLMMI_00422 0.0 ydaO - - E - - - amino acid
NFKMLMMI_00423 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NFKMLMMI_00424 5.03e-80 - - - K - - - acetyltransferase
NFKMLMMI_00425 7.58e-111 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NFKMLMMI_00426 1.04e-83 - - - - - - - -
NFKMLMMI_00427 5.34e-246 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NFKMLMMI_00430 1.06e-53 - - - - - - - -
NFKMLMMI_00431 1.47e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NFKMLMMI_00434 4.61e-44 ydaT - - - - - - -
NFKMLMMI_00435 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
NFKMLMMI_00436 1.7e-64 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NFKMLMMI_00437 6.45e-174 ydbA - - P - - - EcsC protein family
NFKMLMMI_00438 8.2e-08 gsiB - - S ko:K06884 - ko00000 general stress protein
NFKMLMMI_00439 1.04e-75 ydbB - - G - - - Cupin domain
NFKMLMMI_00440 6.59e-76 ydbC - - S - - - Domain of unknown function (DUF4937
NFKMLMMI_00441 6.15e-195 ydbD - - P ko:K07217 - ko00000 Catalase
NFKMLMMI_00442 8.49e-52 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NFKMLMMI_00443 2.07e-171 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NFKMLMMI_00444 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NFKMLMMI_00445 2.66e-146 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NFKMLMMI_00446 4.37e-284 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFKMLMMI_00447 1.85e-225 ydbI - - S - - - AI-2E family transporter
NFKMLMMI_00448 1.79e-216 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_00449 5.5e-164 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NFKMLMMI_00450 1.32e-69 ydbL - - - - - - -
NFKMLMMI_00451 7.84e-256 ydbM - - I - - - acyl-CoA dehydrogenase
NFKMLMMI_00452 2.36e-17 - - - S - - - Fur-regulated basic protein B
NFKMLMMI_00453 6.11e-15 - - - S - - - Fur-regulated basic protein A
NFKMLMMI_00454 1.34e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NFKMLMMI_00455 2.25e-74 ydbP - - CO - - - Thioredoxin
NFKMLMMI_00456 7.23e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NFKMLMMI_00457 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NFKMLMMI_00458 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NFKMLMMI_00459 6.7e-93 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NFKMLMMI_00460 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NFKMLMMI_00461 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NFKMLMMI_00462 7.05e-72 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NFKMLMMI_00463 1.18e-230 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NFKMLMMI_00464 3.01e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NFKMLMMI_00465 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NFKMLMMI_00466 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NFKMLMMI_00467 9.89e-176 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NFKMLMMI_00468 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NFKMLMMI_00469 5.79e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NFKMLMMI_00470 4.02e-238 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NFKMLMMI_00471 3.28e-69 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NFKMLMMI_00472 6.83e-109 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NFKMLMMI_00473 2.67e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFKMLMMI_00474 3.58e-135 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NFKMLMMI_00475 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NFKMLMMI_00476 1.78e-21 - - - - - - - -
NFKMLMMI_00477 4.1e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NFKMLMMI_00485 1.06e-176 - - - I ko:K01066 - ko00000,ko01000 esterase
NFKMLMMI_00486 3.54e-62 ohrB - - O - - - OsmC-like protein
NFKMLMMI_00487 7.77e-65 ohrR - - K - - - Transcriptional regulator
NFKMLMMI_00489 7.99e-71 - - - - - - - -
NFKMLMMI_00490 1.19e-99 - - - K - - - Transcriptional regulator
NFKMLMMI_00491 7.03e-123 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NFKMLMMI_00492 3.05e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NFKMLMMI_00493 2.64e-143 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NFKMLMMI_00494 1e-131 - - - S - - - Protein of unknown function (DUF2812)
NFKMLMMI_00495 6.49e-65 - - - K - - - Transcriptional regulator PadR-like family
NFKMLMMI_00496 1.99e-300 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFKMLMMI_00497 3.96e-238 ydeG - - EGP - - - Major facilitator superfamily
NFKMLMMI_00498 1.41e-63 - - - S - - - Patatin-like phospholipase
NFKMLMMI_00499 5.81e-57 - - - S - - - Patatin-like phospholipase
NFKMLMMI_00501 8.66e-128 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
NFKMLMMI_00502 2.6e-90 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFKMLMMI_00503 8.44e-194 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NFKMLMMI_00504 3.58e-201 - - - S - - - SNARE associated Golgi protein
NFKMLMMI_00505 1.19e-124 yrkC - - G - - - Cupin domain
NFKMLMMI_00506 1.75e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NFKMLMMI_00507 1.73e-186 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NFKMLMMI_00509 6.05e-85 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NFKMLMMI_00510 2.55e-129 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NFKMLMMI_00511 7.14e-63 ydeH - - - - - - -
NFKMLMMI_00512 3.65e-206 - - - S - - - Sodium Bile acid symporter family
NFKMLMMI_00513 1.96e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NFKMLMMI_00514 3.59e-78 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NFKMLMMI_00515 6.33e-278 nhaC_1 - - C - - - antiporter
NFKMLMMI_00516 1.34e-313 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NFKMLMMI_00517 1.74e-129 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_00518 1.41e-239 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
NFKMLMMI_00519 2.13e-129 ydeS - - K - - - Transcriptional regulator
NFKMLMMI_00520 2.99e-192 ydeK - - EG - - - -transporter
NFKMLMMI_00521 1.8e-316 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFKMLMMI_00522 1.16e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
NFKMLMMI_00523 4.86e-33 yraE - - - ko:K06440 - ko00000 -
NFKMLMMI_00524 2.3e-277 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NFKMLMMI_00525 4.76e-84 yraF - - M - - - Spore coat protein
NFKMLMMI_00526 4.73e-47 yraG - - - ko:K06440 - ko00000 -
NFKMLMMI_00527 6.26e-42 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NFKMLMMI_00528 3.37e-162 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
NFKMLMMI_00529 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NFKMLMMI_00530 4.5e-115 ynaD - - J - - - Acetyltransferase (GNAT) domain
NFKMLMMI_00531 1.37e-188 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NFKMLMMI_00532 1.89e-248 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NFKMLMMI_00533 4.16e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NFKMLMMI_00534 5.7e-281 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NFKMLMMI_00535 7.19e-197 - - - K - - - Helix-turn-helix XRE-family like proteins
NFKMLMMI_00536 1.05e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NFKMLMMI_00537 2.24e-101 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NFKMLMMI_00538 1.6e-181 bltR - - K - - - helix_turn_helix, mercury resistance
NFKMLMMI_00539 3.72e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NFKMLMMI_00540 3.02e-89 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NFKMLMMI_00541 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NFKMLMMI_00542 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NFKMLMMI_00543 3.85e-214 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NFKMLMMI_00544 2.98e-315 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NFKMLMMI_00545 7.22e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NFKMLMMI_00546 4.92e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NFKMLMMI_00547 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NFKMLMMI_00548 6.97e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NFKMLMMI_00549 4.85e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NFKMLMMI_00550 5.45e-146 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NFKMLMMI_00551 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NFKMLMMI_00552 6.07e-77 yloU - - S - - - protein conserved in bacteria
NFKMLMMI_00553 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NFKMLMMI_00554 1.69e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NFKMLMMI_00555 3.97e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NFKMLMMI_00556 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NFKMLMMI_00557 2.96e-119 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NFKMLMMI_00558 2.58e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NFKMLMMI_00559 2.08e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NFKMLMMI_00560 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NFKMLMMI_00561 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NFKMLMMI_00562 2.48e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NFKMLMMI_00563 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NFKMLMMI_00564 2.09e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NFKMLMMI_00565 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NFKMLMMI_00566 2e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NFKMLMMI_00567 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NFKMLMMI_00568 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NFKMLMMI_00569 5.66e-79 ylqD - - S - - - YlqD protein
NFKMLMMI_00570 4.17e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NFKMLMMI_00571 2.22e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NFKMLMMI_00572 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NFKMLMMI_00573 5.95e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NFKMLMMI_00574 1.87e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NFKMLMMI_00575 0.0 ylqG - - - - - - -
NFKMLMMI_00576 6.68e-57 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NFKMLMMI_00577 1.66e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NFKMLMMI_00578 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NFKMLMMI_00579 6.19e-208 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NFKMLMMI_00580 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NFKMLMMI_00581 1.05e-311 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NFKMLMMI_00582 1.42e-216 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NFKMLMMI_00583 1.43e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NFKMLMMI_00584 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NFKMLMMI_00585 7.94e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NFKMLMMI_00586 3.14e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NFKMLMMI_00587 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NFKMLMMI_00588 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NFKMLMMI_00589 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NFKMLMMI_00590 4.1e-228 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NFKMLMMI_00591 6.92e-116 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NFKMLMMI_00592 2.02e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NFKMLMMI_00593 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NFKMLMMI_00594 3.78e-76 ylxF - - S - - - MgtE intracellular N domain
NFKMLMMI_00595 7.87e-242 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NFKMLMMI_00596 2.43e-90 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NFKMLMMI_00597 2.56e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NFKMLMMI_00598 3.66e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NFKMLMMI_00599 1.28e-228 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NFKMLMMI_00600 9.42e-231 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NFKMLMMI_00601 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NFKMLMMI_00602 6.3e-142 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NFKMLMMI_00603 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NFKMLMMI_00604 9.02e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NFKMLMMI_00605 4.51e-165 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NFKMLMMI_00606 1.34e-237 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NFKMLMMI_00607 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NFKMLMMI_00608 4.59e-210 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NFKMLMMI_00609 1.43e-196 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NFKMLMMI_00610 2.95e-241 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NFKMLMMI_00611 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NFKMLMMI_00612 1.01e-104 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NFKMLMMI_00613 1.39e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NFKMLMMI_00614 6.74e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NFKMLMMI_00615 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFKMLMMI_00616 2.54e-84 ylxL - - - - - - -
NFKMLMMI_00617 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NFKMLMMI_00618 3.83e-199 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NFKMLMMI_00619 2.03e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NFKMLMMI_00620 1.59e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NFKMLMMI_00621 2.49e-183 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NFKMLMMI_00622 1.48e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NFKMLMMI_00623 8.59e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NFKMLMMI_00624 2.58e-293 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NFKMLMMI_00625 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NFKMLMMI_00626 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NFKMLMMI_00627 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NFKMLMMI_00628 1.35e-262 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NFKMLMMI_00629 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NFKMLMMI_00630 6.16e-63 ylxQ - - J - - - ribosomal protein
NFKMLMMI_00631 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NFKMLMMI_00632 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NFKMLMMI_00633 2.38e-67 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NFKMLMMI_00634 2.64e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NFKMLMMI_00635 6.31e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NFKMLMMI_00636 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NFKMLMMI_00637 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NFKMLMMI_00638 1.33e-228 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NFKMLMMI_00639 9.39e-296 mlpA - - S - - - Belongs to the peptidase M16 family
NFKMLMMI_00640 2.17e-56 ymxH - - S - - - YlmC YmxH family
NFKMLMMI_00641 5.04e-201 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NFKMLMMI_00642 8.03e-70 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NFKMLMMI_00643 7.59e-196 yokA - - L - - - Recombinase
NFKMLMMI_00644 1.36e-111 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NFKMLMMI_00645 7.74e-121 - - - G - - - SMI1-KNR4 cell-wall
NFKMLMMI_00646 2.26e-209 - - - V - - - HNH endonuclease
NFKMLMMI_00647 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NFKMLMMI_00648 3.18e-67 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NFKMLMMI_00650 6.24e-163 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NFKMLMMI_00651 1.04e-52 - - - S - - - YolD-like protein
NFKMLMMI_00652 1.07e-283 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NFKMLMMI_00654 1.34e-214 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NFKMLMMI_00655 8.29e-30 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NFKMLMMI_00656 1.05e-06 - - - - - - - -
NFKMLMMI_00658 1.24e-43 - - - S - - - Bacteriophage holin
NFKMLMMI_00660 7.59e-91 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NFKMLMMI_00661 0.0 - - - M - - - Pectate lyase superfamily protein
NFKMLMMI_00662 8.13e-136 - - - - - - - -
NFKMLMMI_00663 2.04e-242 - - - S - - - Pfam Transposase IS66
NFKMLMMI_00664 8.77e-109 - - - S - - - Phage tail protein
NFKMLMMI_00665 0.0 - - - S - - - peptidoglycan catabolic process
NFKMLMMI_00666 9.09e-73 - - - - - - - -
NFKMLMMI_00669 1.21e-222 - - - A - - - Belongs to the 'phage' integrase family
NFKMLMMI_00670 1.28e-64 - - - - - - - -
NFKMLMMI_00671 2.19e-70 - - - - - - - -
NFKMLMMI_00672 2.02e-106 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
NFKMLMMI_00675 4.74e-66 - - - S - - - Domain of unknown function (DUF2479)
NFKMLMMI_00676 3.02e-65 - - - - - - - -
NFKMLMMI_00678 7.02e-72 - - - - - - - -
NFKMLMMI_00679 2.21e-147 - - - - - - - -
NFKMLMMI_00680 1.42e-109 - - - - - - - -
NFKMLMMI_00681 8.93e-72 - - - - - - - -
NFKMLMMI_00684 4.83e-84 - - - - - - - -
NFKMLMMI_00688 3.95e-107 - - - - - - - -
NFKMLMMI_00693 1.77e-281 - - - - - - - -
NFKMLMMI_00696 1.21e-40 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NFKMLMMI_00697 0.0 - - - - - - - -
NFKMLMMI_00701 3.87e-73 - - - D - - - Tubulin/FtsZ family, GTPase domain
NFKMLMMI_00704 3.51e-275 - - - - - - - -
NFKMLMMI_00706 1.36e-72 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
NFKMLMMI_00707 3.25e-68 - - - - - - - -
NFKMLMMI_00709 1.93e-112 - - - - - - - -
NFKMLMMI_00710 1.34e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NFKMLMMI_00711 1.15e-12 - - - I - - - Acyltransferase family
NFKMLMMI_00712 6.01e-89 yoaW - - - - - - -
NFKMLMMI_00713 4.89e-33 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NFKMLMMI_00724 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NFKMLMMI_00725 7.67e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
NFKMLMMI_00726 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NFKMLMMI_00727 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NFKMLMMI_00728 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NFKMLMMI_00729 5.61e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NFKMLMMI_00730 4.62e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NFKMLMMI_00731 8.84e-272 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NFKMLMMI_00732 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NFKMLMMI_00733 1.4e-154 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NFKMLMMI_00735 2.36e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NFKMLMMI_00736 9.36e-278 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NFKMLMMI_00737 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NFKMLMMI_00738 7.47e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NFKMLMMI_00739 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NFKMLMMI_00740 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NFKMLMMI_00741 1.64e-224 yaaC - - S - - - YaaC-like Protein
NFKMLMMI_00742 2.52e-76 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NFKMLMMI_00743 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NFKMLMMI_00744 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NFKMLMMI_00745 5.34e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NFKMLMMI_00746 7.4e-41 - - - S - - - YlzJ-like protein
NFKMLMMI_00747 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NFKMLMMI_00748 1.38e-166 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_00749 2.76e-290 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_00750 7.8e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_00751 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NFKMLMMI_00752 8.12e-300 albE - - S - - - Peptidase M16
NFKMLMMI_00753 2.09e-303 ymfH - - S - - - zinc protease
NFKMLMMI_00754 1.13e-161 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NFKMLMMI_00755 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
NFKMLMMI_00756 3.66e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
NFKMLMMI_00757 9.2e-166 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NFKMLMMI_00758 2.75e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NFKMLMMI_00759 7.36e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NFKMLMMI_00760 8.4e-237 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NFKMLMMI_00761 4.31e-260 pbpX - - V - - - Beta-lactamase
NFKMLMMI_00762 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NFKMLMMI_00763 3.06e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NFKMLMMI_00764 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NFKMLMMI_00765 1.32e-247 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NFKMLMMI_00766 2.28e-270 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NFKMLMMI_00767 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NFKMLMMI_00768 2.37e-85 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NFKMLMMI_00769 3.93e-116 cotE - - S ko:K06328 - ko00000 Spore coat protein
NFKMLMMI_00770 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NFKMLMMI_00771 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NFKMLMMI_00772 1.97e-117 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
NFKMLMMI_00773 1.77e-202 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NFKMLMMI_00774 9.59e-220 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
NFKMLMMI_00775 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NFKMLMMI_00776 6.16e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
NFKMLMMI_00777 8.2e-306 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NFKMLMMI_00778 7.4e-179 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
NFKMLMMI_00779 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NFKMLMMI_00780 2.37e-36 - - - - - - - -
NFKMLMMI_00782 8.57e-216 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NFKMLMMI_00784 4.86e-59 - - - S - - - dUTPase
NFKMLMMI_00789 4.1e-70 - - - M - - - ArpU family transcriptional regulator
NFKMLMMI_00790 2.64e-93 - - - L - - - Phage integrase family
NFKMLMMI_00791 2.7e-11 ftsK - - D ko:K03466 - ko00000,ko03036 PFAM cell divisionFtsK SpoIIIE
NFKMLMMI_00795 5.24e-22 - - - V - - - HNH endonuclease
NFKMLMMI_00796 3.68e-59 - - - - - - - -
NFKMLMMI_00797 0.0 - - - L - - - Phage Terminase
NFKMLMMI_00798 1.85e-160 - - - S - - - Phage portal protein
NFKMLMMI_00799 7.95e-21 - - - S - - - Phage portal protein
NFKMLMMI_00800 4.57e-108 - - - OU - - - Clp protease
NFKMLMMI_00801 5.24e-187 - - - S - - - Phage capsid family
NFKMLMMI_00802 2.56e-05 - - - - - - - -
NFKMLMMI_00803 2.88e-29 - - - - - - - -
NFKMLMMI_00804 3.54e-30 - - - S - - - Phage head-tail joining protein
NFKMLMMI_00806 3.28e-13 - - - S - - - TIGRFAM phage protein, HK97 gp10 family
NFKMLMMI_00807 8.37e-21 - - - N - - - Maj_tail_phi13 phage major tail , phi13 family protein
NFKMLMMI_00808 4.76e-05 - - - - - - - -
NFKMLMMI_00810 3.49e-169 - - - D - - - phage tail tape measure protein
NFKMLMMI_00812 3e-122 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NFKMLMMI_00813 0.0 - - - M - - - Pectate lyase superfamily protein
NFKMLMMI_00814 6.24e-220 - - - S - - - Domain of unknown function (DUF2479)
NFKMLMMI_00816 5.7e-14 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
NFKMLMMI_00817 2.01e-79 - - - S - - - Pfam:Phage_holin_4_1
NFKMLMMI_00818 3.15e-87 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
NFKMLMMI_00819 5.89e-23 - - - - - - - -
NFKMLMMI_00820 1.88e-51 - - - - - - - -
NFKMLMMI_00822 0.0 - - - C - - - Na+/H+ antiporter family
NFKMLMMI_00823 2.38e-158 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NFKMLMMI_00824 1.1e-191 yycI - - S - - - protein conserved in bacteria
NFKMLMMI_00825 0.0 yycH - - S - - - protein conserved in bacteria
NFKMLMMI_00826 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_00827 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_00832 4.45e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NFKMLMMI_00833 1.06e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFKMLMMI_00834 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NFKMLMMI_00835 5.03e-35 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NFKMLMMI_00837 1.21e-23 yycC - - K - - - YycC-like protein
NFKMLMMI_00838 3.86e-271 - - - M - - - Glycosyltransferase Family 4
NFKMLMMI_00839 5.54e-244 - - - S - - - Ecdysteroid kinase
NFKMLMMI_00840 2.87e-291 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
NFKMLMMI_00841 3.93e-279 - - - M - - - Glycosyltransferase Family 4
NFKMLMMI_00842 1.44e-150 - - - S - - - GlcNAc-PI de-N-acetylase
NFKMLMMI_00843 4.29e-103 - - - KLT - - - COG0515 Serine threonine protein kinase
NFKMLMMI_00844 2.25e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NFKMLMMI_00845 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NFKMLMMI_00846 8.64e-189 yybS - - S - - - membrane
NFKMLMMI_00848 3.93e-104 cotF - - M ko:K06329 - ko00000 Spore coat protein
NFKMLMMI_00849 1.79e-84 yybR - - K - - - Transcriptional regulator
NFKMLMMI_00850 4.01e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NFKMLMMI_00851 4.42e-192 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NFKMLMMI_00852 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NFKMLMMI_00853 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NFKMLMMI_00854 7.61e-142 - - - K - - - FCD domain
NFKMLMMI_00855 3.74e-115 - - - S - - - PFAM DinB family protein
NFKMLMMI_00856 1.96e-184 - - - G - - - Major Facilitator Superfamily
NFKMLMMI_00857 3.76e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NFKMLMMI_00858 1.56e-144 ydgI - - C - - - nitroreductase
NFKMLMMI_00859 2.55e-85 - - - K - - - Winged helix DNA-binding domain
NFKMLMMI_00860 7.02e-190 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NFKMLMMI_00861 7.24e-97 yybA - - K - - - transcriptional
NFKMLMMI_00862 2.85e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
NFKMLMMI_00863 5e-27 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NFKMLMMI_00864 8.63e-130 - - - S - - - Alpha/beta hydrolase family
NFKMLMMI_00865 3.34e-36 - - - - - - - -
NFKMLMMI_00866 1.25e-88 ynaF - - - - - - -
NFKMLMMI_00867 1.17e-30 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NFKMLMMI_00868 3.84e-38 - - - L - - - Recombinase
NFKMLMMI_00869 1.07e-157 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NFKMLMMI_00872 2.39e-45 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
NFKMLMMI_00873 7.7e-73 yddI - - - - - - -
NFKMLMMI_00874 7.23e-201 yddH - - M - - - Lysozyme-like
NFKMLMMI_00875 5.75e-254 yddG - - S - - - maturation of SSU-rRNA
NFKMLMMI_00876 4.11e-49 - - - S - - - Domain of unknown function (DUF1874)
NFKMLMMI_00877 0.0 yddE - - S - - - AAA-like domain
NFKMLMMI_00878 2.63e-97 yddD - - S - - - TcpE family
NFKMLMMI_00879 1.35e-33 yddC - - - - - - -
NFKMLMMI_00880 8.56e-164 yddB - - S - - - Conjugative transposon protein TcpC
NFKMLMMI_00882 2.46e-53 yddA - - - - - - -
NFKMLMMI_00886 7.64e-231 nicK - - L ko:K07467 - ko00000 Replication initiation factor
NFKMLMMI_00887 3.64e-308 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
NFKMLMMI_00888 3.78e-50 - - - S - - - Bacterial protein of unknown function (DUF961)
NFKMLMMI_00890 8.45e-32 - - - - - - - -
NFKMLMMI_00891 5.7e-15 - - - - - - - -
NFKMLMMI_00892 1.31e-42 - - - K - - - Transcriptional
NFKMLMMI_00893 7.12e-54 - - - E - - - IrrE N-terminal-like domain
NFKMLMMI_00895 2.92e-14 - - - KLT - - - serine threonine protein kinase
NFKMLMMI_00896 2.42e-30 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
NFKMLMMI_00897 1.41e-158 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NFKMLMMI_00898 7.39e-264 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NFKMLMMI_00899 4.75e-193 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NFKMLMMI_00900 2.8e-311 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NFKMLMMI_00901 9.47e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFKMLMMI_00902 7.31e-218 ccpB - - K - - - Transcriptional regulator
NFKMLMMI_00903 2.49e-179 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NFKMLMMI_00904 6.58e-112 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NFKMLMMI_00905 3.59e-123 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NFKMLMMI_00906 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NFKMLMMI_00907 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NFKMLMMI_00908 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NFKMLMMI_00909 6.32e-253 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NFKMLMMI_00910 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NFKMLMMI_00911 1.82e-45 yyzM - - S - - - protein conserved in bacteria
NFKMLMMI_00912 3.84e-215 yyaD - - S - - - Membrane
NFKMLMMI_00913 2.63e-74 yhhY - - K - - - FR47-like protein
NFKMLMMI_00914 1.3e-139 yyaC - - S - - - Sporulation protein YyaC
NFKMLMMI_00915 2.76e-187 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NFKMLMMI_00916 2.49e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NFKMLMMI_00917 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NFKMLMMI_00918 2.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NFKMLMMI_00919 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NFKMLMMI_00920 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NFKMLMMI_00921 7.08e-137 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NFKMLMMI_00922 6.08e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NFKMLMMI_00923 1.84e-67 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NFKMLMMI_00924 8.39e-316 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NFKMLMMI_00925 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NFKMLMMI_00926 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NFKMLMMI_00927 1.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NFKMLMMI_00928 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
NFKMLMMI_00929 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NFKMLMMI_00930 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NFKMLMMI_00931 9.96e-152 ecsC - - S - - - EcsC protein family
NFKMLMMI_00932 1.68e-274 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NFKMLMMI_00933 1.65e-303 yhfA - - C - - - membrane
NFKMLMMI_00934 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NFKMLMMI_00935 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NFKMLMMI_00936 9.19e-253 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NFKMLMMI_00937 3.4e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NFKMLMMI_00938 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NFKMLMMI_00939 5.15e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_00940 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NFKMLMMI_00941 2.04e-226 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NFKMLMMI_00943 1.66e-247 yhfE - - G - - - peptidase M42
NFKMLMMI_00944 3.75e-286 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFKMLMMI_00945 2.4e-173 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NFKMLMMI_00946 1.07e-240 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NFKMLMMI_00947 3.92e-137 yhfK - - GM - - - NmrA-like family
NFKMLMMI_00948 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NFKMLMMI_00949 9.31e-84 yhfM - - - - - - -
NFKMLMMI_00950 1.33e-293 yhfN - - O - - - Peptidase M48
NFKMLMMI_00951 1.24e-258 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NFKMLMMI_00952 1.78e-163 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NFKMLMMI_00953 4.57e-129 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NFKMLMMI_00954 8.49e-245 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NFKMLMMI_00955 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NFKMLMMI_00956 2.32e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NFKMLMMI_00957 2.08e-272 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NFKMLMMI_00958 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NFKMLMMI_00959 2.73e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_00960 5.49e-42 yhzC - - S - - - IDEAL
NFKMLMMI_00961 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NFKMLMMI_00962 4.21e-74 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NFKMLMMI_00963 1.28e-213 - - - S - - - Acetyltransferase, GNAT family
NFKMLMMI_00964 1.53e-156 yrpD - - S - - - Domain of unknown function, YrpD
NFKMLMMI_00965 7.11e-57 yhjA - - S - - - Excalibur calcium-binding domain
NFKMLMMI_00966 2.64e-63 - - - S - - - Belongs to the UPF0145 family
NFKMLMMI_00967 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFKMLMMI_00968 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
NFKMLMMI_00969 2.77e-63 yhjD - - - - - - -
NFKMLMMI_00970 8.02e-136 yhjE - - S - - - SNARE associated Golgi protein
NFKMLMMI_00971 1.3e-116 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NFKMLMMI_00972 0.0 yhjG - - CH - - - FAD binding domain
NFKMLMMI_00973 9.88e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_00974 2.03e-254 yhjN - - S ko:K07120 - ko00000 membrane
NFKMLMMI_00975 1.56e-260 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_00976 1.24e-138 - - - K - - - QacR-like protein, C-terminal region
NFKMLMMI_00977 3.47e-108 yhjR - - S - - - Rubrerythrin
NFKMLMMI_00978 8.81e-152 ydfS - - S - - - Protein of unknown function (DUF421)
NFKMLMMI_00979 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NFKMLMMI_00980 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NFKMLMMI_00981 7.47e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NFKMLMMI_00982 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NFKMLMMI_00983 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NFKMLMMI_00984 3.36e-66 yisB - - V - - - COG1403 Restriction endonuclease
NFKMLMMI_00985 5.49e-42 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NFKMLMMI_00986 2.37e-77 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NFKMLMMI_00987 1.44e-31 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NFKMLMMI_00988 7.69e-103 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NFKMLMMI_00989 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NFKMLMMI_00990 2.45e-13 yisI - - S - - - Spo0E like sporulation regulatory protein
NFKMLMMI_00991 2.25e-211 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NFKMLMMI_00992 4.48e-78 yisL - - S - - - UPF0344 protein
NFKMLMMI_00993 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NFKMLMMI_00994 5.25e-115 yisN - - S - - - Protein of unknown function (DUF2777)
NFKMLMMI_00995 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NFKMLMMI_00996 6.09e-150 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NFKMLMMI_00997 1.69e-307 yisQ - - V - - - Mate efflux family protein
NFKMLMMI_00998 1.77e-201 yisR - - K - - - Transcriptional regulator
NFKMLMMI_00999 3.87e-179 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NFKMLMMI_01000 2.32e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NFKMLMMI_01001 3.26e-100 yisT - - S - - - DinB family
NFKMLMMI_01002 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
NFKMLMMI_01003 1.72e-232 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFKMLMMI_01004 9.1e-82 yisX - - S - - - Pentapeptide repeats (9 copies)
NFKMLMMI_01005 6.78e-100 - - - S - - - Acetyltransferase (GNAT) domain
NFKMLMMI_01006 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NFKMLMMI_01007 7.44e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NFKMLMMI_01008 3.3e-199 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NFKMLMMI_01009 2.3e-186 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
NFKMLMMI_01010 4.19e-158 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NFKMLMMI_01011 1.86e-87 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NFKMLMMI_01012 4.22e-293 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NFKMLMMI_01013 8.05e-196 yitS - - S - - - protein conserved in bacteria
NFKMLMMI_01014 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NFKMLMMI_01015 3.05e-104 ipi - - S - - - Intracellular proteinase inhibitor
NFKMLMMI_01016 1.23e-35 - - - S - - - Protein of unknown function (DUF3813)
NFKMLMMI_01017 1.49e-11 - - - - - - - -
NFKMLMMI_01018 3.84e-192 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NFKMLMMI_01019 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NFKMLMMI_01020 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NFKMLMMI_01021 3.29e-92 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NFKMLMMI_01022 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NFKMLMMI_01023 4.44e-117 yitZ - - G - - - Major Facilitator Superfamily
NFKMLMMI_01024 4.41e-247 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NFKMLMMI_01025 4.35e-282 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NFKMLMMI_01026 3.58e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NFKMLMMI_01027 5.32e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NFKMLMMI_01028 4.59e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NFKMLMMI_01029 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NFKMLMMI_01030 1.78e-220 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NFKMLMMI_01031 2.07e-38 yjzC - - S - - - YjzC-like protein
NFKMLMMI_01032 3.71e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
NFKMLMMI_01033 6.59e-171 yjaU - - I - - - carboxylic ester hydrolase activity
NFKMLMMI_01034 7.04e-127 yjaV - - - - - - -
NFKMLMMI_01035 8.66e-209 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NFKMLMMI_01036 3.74e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NFKMLMMI_01037 1.46e-37 yjzB - - - - - - -
NFKMLMMI_01038 1.26e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NFKMLMMI_01039 1.24e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NFKMLMMI_01040 2.47e-179 yjaZ - - O - - - Zn-dependent protease
NFKMLMMI_01041 1.81e-226 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_01042 4.48e-232 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_01043 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NFKMLMMI_01044 8.55e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFKMLMMI_01045 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFKMLMMI_01046 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
NFKMLMMI_01047 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NFKMLMMI_01048 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NFKMLMMI_01049 2.08e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFKMLMMI_01050 1.46e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFKMLMMI_01051 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NFKMLMMI_01052 1.33e-158 yhcW - - S ko:K07025 - ko00000 hydrolase
NFKMLMMI_01053 5.88e-89 yhcV - - S - - - COG0517 FOG CBS domain
NFKMLMMI_01054 1.88e-83 yhcU - - S - - - Family of unknown function (DUF5365)
NFKMLMMI_01055 2.24e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NFKMLMMI_01056 3.17e-128 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NFKMLMMI_01057 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NFKMLMMI_01058 2.2e-149 yhcQ - - M - - - Spore coat protein
NFKMLMMI_01059 3.99e-199 yhcP - - - - - - -
NFKMLMMI_01060 6.26e-101 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NFKMLMMI_01061 5.08e-60 yhcM - - - - - - -
NFKMLMMI_01062 1.79e-49 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NFKMLMMI_01063 1.11e-302 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFKMLMMI_01064 2.76e-230 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NFKMLMMI_01065 6.9e-161 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NFKMLMMI_01066 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NFKMLMMI_01067 1.87e-201 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NFKMLMMI_01068 3.74e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_01069 8.89e-147 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_01070 3.06e-77 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_01071 7.54e-65 - - - - - - - -
NFKMLMMI_01072 1.03e-65 yhcC - - - - - - -
NFKMLMMI_01073 2.61e-128 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NFKMLMMI_01074 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NFKMLMMI_01075 2.98e-130 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NFKMLMMI_01076 5.25e-76 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NFKMLMMI_01077 2.12e-276 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NFKMLMMI_01078 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NFKMLMMI_01079 1.23e-07 - - - - - - - -
NFKMLMMI_01080 7.48e-85 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NFKMLMMI_01081 2.51e-76 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NFKMLMMI_01082 3.35e-132 yhbD - - K - - - Protein of unknown function (DUF4004)
NFKMLMMI_01083 2.31e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NFKMLMMI_01084 8.37e-216 yhbB - - S - - - Putative amidase domain
NFKMLMMI_01085 2.14e-280 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NFKMLMMI_01086 1.34e-138 yhzB - - S - - - B3/4 domain
NFKMLMMI_01088 5.45e-31 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_01089 2.4e-102 ygaO - - - - - - -
NFKMLMMI_01090 1.62e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NFKMLMMI_01092 1.37e-269 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NFKMLMMI_01093 6.5e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NFKMLMMI_01094 2.34e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NFKMLMMI_01095 1.02e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NFKMLMMI_01096 2.39e-227 - - - S ko:K07045 - ko00000 Amidohydrolase
NFKMLMMI_01097 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NFKMLMMI_01098 5.17e-165 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_01099 5.45e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_01100 6.2e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFKMLMMI_01101 2.33e-185 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NFKMLMMI_01102 1.69e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
NFKMLMMI_01104 3.15e-313 ygaK - - C - - - Berberine and berberine like
NFKMLMMI_01105 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NFKMLMMI_01106 1.04e-163 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NFKMLMMI_01107 1.94e-127 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NFKMLMMI_01109 2.52e-119 - - - P - - - Probably functions as a manganese efflux pump
NFKMLMMI_01110 3.85e-144 - - - K - - - Protein of unknown function (DUF1232)
NFKMLMMI_01112 1.65e-265 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NFKMLMMI_01115 4.12e-258 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NFKMLMMI_01117 4.13e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NFKMLMMI_01118 5.48e-298 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NFKMLMMI_01119 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NFKMLMMI_01120 1.03e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NFKMLMMI_01121 2.69e-193 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NFKMLMMI_01122 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NFKMLMMI_01123 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NFKMLMMI_01124 4.44e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NFKMLMMI_01125 5.36e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NFKMLMMI_01126 2.51e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NFKMLMMI_01127 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NFKMLMMI_01128 5.53e-87 yqhY - - S - - - protein conserved in bacteria
NFKMLMMI_01129 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NFKMLMMI_01130 2.59e-83 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NFKMLMMI_01131 1.88e-86 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NFKMLMMI_01132 1.3e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NFKMLMMI_01133 4.98e-129 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NFKMLMMI_01134 3.02e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NFKMLMMI_01135 5.28e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NFKMLMMI_01136 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NFKMLMMI_01137 2.23e-108 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NFKMLMMI_01138 7.55e-213 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NFKMLMMI_01139 1.64e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
NFKMLMMI_01140 9.69e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NFKMLMMI_01141 2.75e-245 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NFKMLMMI_01142 2.13e-113 yqhR - - S - - - Conserved membrane protein YqhR
NFKMLMMI_01143 2.25e-215 yqhQ - - S - - - Protein of unknown function (DUF1385)
NFKMLMMI_01144 8.59e-80 yqhP - - - - - - -
NFKMLMMI_01145 2.51e-203 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NFKMLMMI_01146 1.14e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NFKMLMMI_01147 1.25e-201 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NFKMLMMI_01148 2.33e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NFKMLMMI_01149 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NFKMLMMI_01150 2.74e-99 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NFKMLMMI_01151 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFKMLMMI_01152 4.43e-77 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NFKMLMMI_01153 2.31e-29 ymzA - - - - - - -
NFKMLMMI_01154 1.87e-53 - - - - - - - -
NFKMLMMI_01155 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NFKMLMMI_01156 7.19e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NFKMLMMI_01157 9.08e-72 ymaF - - S - - - YmaF family
NFKMLMMI_01159 1.17e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NFKMLMMI_01160 1.76e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NFKMLMMI_01161 9.17e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NFKMLMMI_01162 3.08e-151 ymaC - - S - - - Replication protein
NFKMLMMI_01163 2.64e-07 - - - - - - - -
NFKMLMMI_01164 9.4e-317 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NFKMLMMI_01165 9.32e-81 ymzB - - - - - - -
NFKMLMMI_01166 3.52e-149 yoaK - - S - - - Membrane
NFKMLMMI_01167 3e-93 nucB - - M - - - Deoxyribonuclease NucA/NucB
NFKMLMMI_01168 4.53e-283 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NFKMLMMI_01169 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
NFKMLMMI_01170 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NFKMLMMI_01171 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NFKMLMMI_01172 4.14e-121 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NFKMLMMI_01173 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NFKMLMMI_01174 7.4e-41 ykzG - - S - - - Belongs to the UPF0356 family
NFKMLMMI_01175 3.14e-180 ykrA - - S - - - hydrolases of the HAD superfamily
NFKMLMMI_01176 1.49e-126 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NFKMLMMI_01177 4.93e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NFKMLMMI_01178 9.3e-84 ykyA - - L - - - Putative cell-wall binding lipoprotein
NFKMLMMI_01179 1.04e-249 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NFKMLMMI_01180 5.84e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NFKMLMMI_01181 6.09e-294 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NFKMLMMI_01182 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NFKMLMMI_01183 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NFKMLMMI_01184 3.33e-173 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NFKMLMMI_01185 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NFKMLMMI_01186 5.44e-56 yktA - - S - - - Belongs to the UPF0223 family
NFKMLMMI_01187 2.73e-153 yktB - - S - - - Belongs to the UPF0637 family
NFKMLMMI_01188 7.89e-32 ykzI - - - - - - -
NFKMLMMI_01189 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NFKMLMMI_01190 1.08e-92 ykzC - - S - - - Acetyltransferase (GNAT) family
NFKMLMMI_01191 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NFKMLMMI_01192 9.3e-32 ylaA - - - - - - -
NFKMLMMI_01194 1.97e-52 ylaE - - - - - - -
NFKMLMMI_01195 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
NFKMLMMI_01196 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NFKMLMMI_01197 1.41e-64 - - - S - - - YlaH-like protein
NFKMLMMI_01198 7.95e-45 ylaI - - S - - - protein conserved in bacteria
NFKMLMMI_01199 2.67e-129 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NFKMLMMI_01200 4.29e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NFKMLMMI_01201 4.45e-104 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NFKMLMMI_01202 6.76e-217 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NFKMLMMI_01203 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
NFKMLMMI_01204 3.73e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NFKMLMMI_01205 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NFKMLMMI_01206 3.88e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NFKMLMMI_01207 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NFKMLMMI_01208 3.95e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NFKMLMMI_01209 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NFKMLMMI_01210 3.43e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NFKMLMMI_01211 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NFKMLMMI_01212 1.35e-207 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NFKMLMMI_01213 8.01e-77 ylbA - - S - - - YugN-like family
NFKMLMMI_01214 1.31e-93 ylbB - - T - - - COG0517 FOG CBS domain
NFKMLMMI_01215 5.8e-248 ylbC - - S - - - protein with SCP PR1 domains
NFKMLMMI_01216 5.5e-83 ylbD - - S - - - Putative coat protein
NFKMLMMI_01217 1.73e-48 ylbE - - S - - - YlbE-like protein
NFKMLMMI_01218 3.73e-94 ylbF - - S - - - Belongs to the UPF0342 family
NFKMLMMI_01219 4.62e-56 ylbG - - S - - - UPF0298 protein
NFKMLMMI_01220 4.27e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NFKMLMMI_01221 2.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NFKMLMMI_01222 8.16e-268 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NFKMLMMI_01223 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NFKMLMMI_01224 7.74e-234 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NFKMLMMI_01225 1.26e-281 ylbM - - S - - - Belongs to the UPF0348 family
NFKMLMMI_01226 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NFKMLMMI_01227 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NFKMLMMI_01228 1.65e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NFKMLMMI_01229 2.68e-115 ylbP - - K - - - n-acetyltransferase
NFKMLMMI_01230 4.46e-190 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NFKMLMMI_01231 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NFKMLMMI_01232 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NFKMLMMI_01233 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NFKMLMMI_01234 2.81e-67 ftsL - - D - - - Essential cell division protein
NFKMLMMI_01235 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NFKMLMMI_01236 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NFKMLMMI_01237 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NFKMLMMI_01238 2.36e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NFKMLMMI_01239 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NFKMLMMI_01240 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NFKMLMMI_01241 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NFKMLMMI_01242 3.07e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NFKMLMMI_01243 3.74e-170 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NFKMLMMI_01244 3.7e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NFKMLMMI_01245 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NFKMLMMI_01246 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NFKMLMMI_01247 8.58e-79 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NFKMLMMI_01248 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NFKMLMMI_01249 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NFKMLMMI_01250 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NFKMLMMI_01251 1.22e-247 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NFKMLMMI_01252 1.85e-245 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NFKMLMMI_01253 1.96e-157 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NFKMLMMI_01254 1.23e-110 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NFKMLMMI_01255 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NFKMLMMI_01256 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NFKMLMMI_01257 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NFKMLMMI_01258 9.32e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NFKMLMMI_01259 9.69e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NFKMLMMI_01260 1.92e-113 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NFKMLMMI_01261 4.65e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NFKMLMMI_01262 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NFKMLMMI_01263 6.9e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NFKMLMMI_01264 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NFKMLMMI_01265 2.04e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NFKMLMMI_01266 6.68e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NFKMLMMI_01267 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NFKMLMMI_01268 2.53e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NFKMLMMI_01269 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFKMLMMI_01270 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFKMLMMI_01271 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NFKMLMMI_01272 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NFKMLMMI_01273 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NFKMLMMI_01274 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NFKMLMMI_01275 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NFKMLMMI_01276 3.62e-220 ybaC - - S - - - Alpha/beta hydrolase family
NFKMLMMI_01277 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NFKMLMMI_01278 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NFKMLMMI_01279 6.11e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NFKMLMMI_01280 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NFKMLMMI_01281 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NFKMLMMI_01282 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NFKMLMMI_01283 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NFKMLMMI_01284 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NFKMLMMI_01285 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NFKMLMMI_01286 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NFKMLMMI_01287 1.92e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NFKMLMMI_01288 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NFKMLMMI_01289 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NFKMLMMI_01290 2.58e-120 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NFKMLMMI_01291 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NFKMLMMI_01292 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NFKMLMMI_01293 1.05e-119 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NFKMLMMI_01294 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NFKMLMMI_01295 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NFKMLMMI_01296 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NFKMLMMI_01297 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NFKMLMMI_01298 1.82e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NFKMLMMI_01299 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NFKMLMMI_01300 3.16e-180 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NFKMLMMI_01301 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NFKMLMMI_01302 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NFKMLMMI_01303 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NFKMLMMI_01304 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NFKMLMMI_01305 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFKMLMMI_01306 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NFKMLMMI_01307 6.9e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NFKMLMMI_01308 1.06e-184 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NFKMLMMI_01309 8.86e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NFKMLMMI_01310 3.42e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NFKMLMMI_01311 3.79e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NFKMLMMI_01312 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NFKMLMMI_01313 4.46e-179 ybaJ - - Q - - - Methyltransferase domain
NFKMLMMI_01315 2.28e-99 ybaK - - S - - - Protein of unknown function (DUF2521)
NFKMLMMI_01316 4.3e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NFKMLMMI_01317 4.58e-247 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NFKMLMMI_01318 1.95e-102 gerD - - - ko:K06294 - ko00000 -
NFKMLMMI_01319 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NFKMLMMI_01320 1.09e-174 pdaB - - G - - - Polysaccharide deacetylase
NFKMLMMI_01321 1.15e-54 ycgF - - E - - - Lysine exporter protein LysE YggA
NFKMLMMI_01322 6.64e-76 ycgF - - E - - - Lysine exporter protein LysE YggA
NFKMLMMI_01323 5.9e-183 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NFKMLMMI_01324 2.03e-305 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NFKMLMMI_01325 6.25e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NFKMLMMI_01326 2.05e-188 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NFKMLMMI_01327 1.69e-164 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
NFKMLMMI_01328 3.35e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_01329 1.43e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NFKMLMMI_01330 9.05e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NFKMLMMI_01331 8.28e-178 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NFKMLMMI_01332 1.53e-213 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NFKMLMMI_01333 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NFKMLMMI_01334 1.05e-309 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFKMLMMI_01335 7.58e-286 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NFKMLMMI_01336 4.86e-235 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NFKMLMMI_01337 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NFKMLMMI_01338 1.64e-72 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NFKMLMMI_01339 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NFKMLMMI_01340 1.41e-49 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NFKMLMMI_01341 9.85e-281 yciC - - S - - - GTPases (G3E family)
NFKMLMMI_01342 2.55e-221 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NFKMLMMI_01343 3.65e-94 yckC - - S - - - membrane
NFKMLMMI_01344 7.52e-65 - - - S - - - Protein of unknown function (DUF2680)
NFKMLMMI_01345 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NFKMLMMI_01346 1.04e-85 nin - - S - - - Competence protein J (ComJ)
NFKMLMMI_01347 2.67e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
NFKMLMMI_01348 7.04e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NFKMLMMI_01349 6.52e-132 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NFKMLMMI_01350 2.89e-84 hxlR - - K - - - transcriptional
NFKMLMMI_01356 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_01357 1.94e-99 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFKMLMMI_01358 1.97e-59 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
NFKMLMMI_01359 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFKMLMMI_01360 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NFKMLMMI_01361 4.69e-238 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NFKMLMMI_01362 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NFKMLMMI_01363 9.29e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
NFKMLMMI_01364 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NFKMLMMI_01365 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NFKMLMMI_01366 2.51e-135 bdbD - - O - - - Thioredoxin
NFKMLMMI_01367 5.06e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NFKMLMMI_01368 5.24e-188 - - - S - - - Metallo-peptidase family M12
NFKMLMMI_01369 6.1e-128 yvgT - - S - - - membrane
NFKMLMMI_01370 2.48e-96 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NFKMLMMI_01371 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NFKMLMMI_01372 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NFKMLMMI_01373 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NFKMLMMI_01374 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NFKMLMMI_01375 1.55e-110 yvgO - - - - - - -
NFKMLMMI_01376 1.77e-200 yvgN - - S - - - reductase
NFKMLMMI_01377 1.44e-229 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NFKMLMMI_01378 3.65e-235 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NFKMLMMI_01379 1.12e-216 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NFKMLMMI_01380 3.01e-237 - - - T - - - Histidine kinase
NFKMLMMI_01381 2.17e-146 yfiK - - K - - - Regulator
NFKMLMMI_01382 1.21e-128 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
NFKMLMMI_01383 4.92e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NFKMLMMI_01384 8.02e-204 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NFKMLMMI_01385 2.24e-203 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NFKMLMMI_01386 3.8e-210 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NFKMLMMI_01387 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NFKMLMMI_01388 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NFKMLMMI_01389 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NFKMLMMI_01390 2.17e-153 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NFKMLMMI_01391 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NFKMLMMI_01392 6.08e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_01393 9.44e-217 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_01394 6.61e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NFKMLMMI_01395 1.37e-78 yvrL - - S - - - Regulatory protein YrvL
NFKMLMMI_01396 9.98e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NFKMLMMI_01397 1.88e-21 - - - S - - - YvrJ protein family
NFKMLMMI_01398 1.47e-130 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NFKMLMMI_01399 1.14e-48 - - - - - - - -
NFKMLMMI_01400 4.48e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_01401 0.0 yvrG - - T - - - Histidine kinase
NFKMLMMI_01402 2.36e-213 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NFKMLMMI_01403 4.79e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NFKMLMMI_01404 1.07e-211 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NFKMLMMI_01405 1.64e-223 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_01406 1.87e-257 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NFKMLMMI_01407 3.89e-125 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NFKMLMMI_01408 9.45e-281 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_01409 7.39e-65 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NFKMLMMI_01410 6e-128 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NFKMLMMI_01411 1.33e-165 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NFKMLMMI_01412 6.74e-159 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NFKMLMMI_01413 2.86e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_01414 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFKMLMMI_01415 9.22e-248 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NFKMLMMI_01416 3e-235 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NFKMLMMI_01417 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NFKMLMMI_01418 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
NFKMLMMI_01419 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NFKMLMMI_01420 6.7e-196 yuxN - - K - - - Transcriptional regulator
NFKMLMMI_01421 2.68e-32 - - - - - - - -
NFKMLMMI_01422 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_01423 2.06e-160 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_01424 8.65e-295 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NFKMLMMI_01425 5.63e-101 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NFKMLMMI_01426 1.77e-177 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NFKMLMMI_01427 1.86e-78 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NFKMLMMI_01428 1.59e-288 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NFKMLMMI_01429 2.79e-62 - - - S - - - YusW-like protein
NFKMLMMI_01430 1.06e-191 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NFKMLMMI_01431 1.46e-50 yusU - - S - - - Protein of unknown function (DUF2573)
NFKMLMMI_01432 3.73e-159 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NFKMLMMI_01433 1.48e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
NFKMLMMI_01434 6.56e-74 - - - L - - - PFAM Restriction endonuclease BamHI
NFKMLMMI_01435 0.0 yusP - - P - - - Major facilitator superfamily
NFKMLMMI_01436 1.47e-86 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NFKMLMMI_01437 3.53e-69 yusN - - M - - - Coat F domain
NFKMLMMI_01438 7.03e-53 - - - - - - - -
NFKMLMMI_01439 6.69e-209 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NFKMLMMI_01440 1.72e-10 - - - S - - - YuzL-like protein
NFKMLMMI_01441 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NFKMLMMI_01442 3.02e-275 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NFKMLMMI_01443 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NFKMLMMI_01444 4.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NFKMLMMI_01445 1.19e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NFKMLMMI_01446 2.99e-53 yusG - - S - - - Protein of unknown function (DUF2553)
NFKMLMMI_01447 5.93e-30 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NFKMLMMI_01448 2.25e-70 yusE - - CO - - - Thioredoxin
NFKMLMMI_01449 5.08e-74 yusD - - S - - - SCP-2 sterol transfer family
NFKMLMMI_01450 1.24e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NFKMLMMI_01451 3.3e-135 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NFKMLMMI_01452 2.88e-183 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NFKMLMMI_01453 2.97e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NFKMLMMI_01455 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NFKMLMMI_01456 1.75e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NFKMLMMI_01457 3.01e-294 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NFKMLMMI_01458 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NFKMLMMI_01459 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NFKMLMMI_01460 1.06e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NFKMLMMI_01461 7.45e-94 yncE - - S - - - Protein of unknown function (DUF2691)
NFKMLMMI_01462 1.09e-128 - - - Q - - - ubiE/COQ5 methyltransferase family
NFKMLMMI_01463 2.19e-251 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NFKMLMMI_01464 1.36e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NFKMLMMI_01468 1.34e-95 - - - - - - - -
NFKMLMMI_01470 8.02e-204 - - - K - - - helix_turn_helix, mercury resistance
NFKMLMMI_01471 8.37e-232 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NFKMLMMI_01472 4.58e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NFKMLMMI_01473 7.16e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NFKMLMMI_01474 3.4e-198 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NFKMLMMI_01475 6.94e-202 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NFKMLMMI_01476 8.02e-171 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NFKMLMMI_01477 1.49e-252 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_01478 3.33e-209 bsn - - L - - - Ribonuclease
NFKMLMMI_01479 7.27e-285 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NFKMLMMI_01480 2.55e-287 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NFKMLMMI_01481 8.83e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_01482 6.3e-86 - - - - - - - -
NFKMLMMI_01483 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NFKMLMMI_01484 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NFKMLMMI_01485 1.19e-58 ymaB - - S - - - MutT family
NFKMLMMI_01486 3.91e-05 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NFKMLMMI_01487 8.13e-112 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NFKMLMMI_01488 2.58e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NFKMLMMI_01489 9.64e-289 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NFKMLMMI_01490 5.35e-307 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NFKMLMMI_01491 8.18e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NFKMLMMI_01492 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NFKMLMMI_01495 6.66e-151 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NFKMLMMI_01496 1.54e-271 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NFKMLMMI_01497 8.41e-314 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
NFKMLMMI_01498 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NFKMLMMI_01499 6.16e-263 xylR - - GK - - - ROK family
NFKMLMMI_01500 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NFKMLMMI_01501 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NFKMLMMI_01502 4.44e-150 - 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NFKMLMMI_01503 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NFKMLMMI_01504 7.81e-116 - - - K - - - Transcriptional regulator, TetR family
NFKMLMMI_01505 8.96e-223 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NFKMLMMI_01507 7.33e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NFKMLMMI_01508 0.000425 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NFKMLMMI_01509 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NFKMLMMI_01510 2.12e-273 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NFKMLMMI_01513 0.000125 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NFKMLMMI_01515 1.52e-161 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NFKMLMMI_01516 6.5e-189 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NFKMLMMI_01517 1.06e-188 - - - K - - - Transcriptional regulator
NFKMLMMI_01518 7.21e-154 ygaZ - - E - - - AzlC protein
NFKMLMMI_01519 7.23e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NFKMLMMI_01520 1.41e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NFKMLMMI_01521 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NFKMLMMI_01522 9.52e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NFKMLMMI_01523 9.68e-138 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NFKMLMMI_01524 1.4e-283 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NFKMLMMI_01525 1.87e-127 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NFKMLMMI_01526 2.47e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NFKMLMMI_01527 7.72e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NFKMLMMI_01528 1.8e-248 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NFKMLMMI_01529 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
NFKMLMMI_01530 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NFKMLMMI_01531 2.16e-25 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NFKMLMMI_01532 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NFKMLMMI_01533 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NFKMLMMI_01534 1.15e-136 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NFKMLMMI_01535 1.1e-186 ytpQ - - S - - - Belongs to the UPF0354 family
NFKMLMMI_01536 2.23e-75 ytpP - - CO - - - Thioredoxin
NFKMLMMI_01537 5.33e-98 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NFKMLMMI_01538 8.38e-258 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NFKMLMMI_01539 9.96e-69 ytzB - - S - - - small secreted protein
NFKMLMMI_01540 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NFKMLMMI_01541 1.41e-204 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NFKMLMMI_01542 4.34e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NFKMLMMI_01543 4.54e-59 ytzH - - S - - - YtzH-like protein
NFKMLMMI_01544 3.42e-198 ytmP - - M - - - Phosphotransferase
NFKMLMMI_01545 1.86e-214 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NFKMLMMI_01546 2.86e-198 ytlQ - - - - - - -
NFKMLMMI_01547 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NFKMLMMI_01548 4.05e-214 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NFKMLMMI_01549 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NFKMLMMI_01550 3.89e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NFKMLMMI_01551 1.21e-251 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NFKMLMMI_01552 1.92e-149 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NFKMLMMI_01553 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NFKMLMMI_01554 4.25e-160 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NFKMLMMI_01555 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFKMLMMI_01556 2.31e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NFKMLMMI_01557 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NFKMLMMI_01558 3.57e-35 yteV - - S - - - Sporulation protein Cse60
NFKMLMMI_01559 3.97e-232 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_01560 3.41e-296 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NFKMLMMI_01561 3.37e-77 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NFKMLMMI_01562 5.59e-308 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NFKMLMMI_01563 6.31e-96 - - - M - - - Acetyltransferase (GNAT) domain
NFKMLMMI_01564 8.6e-69 ytwF - - P - - - Sulfurtransferase
NFKMLMMI_01565 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NFKMLMMI_01566 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
NFKMLMMI_01567 2.97e-171 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NFKMLMMI_01568 2.16e-265 yttB - - EGP - - - Major facilitator superfamily
NFKMLMMI_01569 4.62e-130 ywaF - - S - - - Integral membrane protein
NFKMLMMI_01570 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NFKMLMMI_01571 7.67e-171 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_01572 2.32e-216 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NFKMLMMI_01573 5.19e-157 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_01574 3.54e-258 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NFKMLMMI_01575 7.08e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_01576 1.47e-190 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NFKMLMMI_01577 2.63e-203 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NFKMLMMI_01578 2.23e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NFKMLMMI_01579 9.08e-202 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_01580 6.32e-86 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NFKMLMMI_01582 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
NFKMLMMI_01583 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NFKMLMMI_01584 4.07e-133 ytqB - - J - - - Putative rRNA methylase
NFKMLMMI_01586 2.17e-266 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NFKMLMMI_01587 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NFKMLMMI_01588 1.23e-78 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NFKMLMMI_01589 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NFKMLMMI_01590 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NFKMLMMI_01591 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NFKMLMMI_01592 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NFKMLMMI_01593 1.65e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
NFKMLMMI_01594 6.15e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NFKMLMMI_01595 6.07e-228 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NFKMLMMI_01596 1.38e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NFKMLMMI_01597 3.42e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NFKMLMMI_01598 5.86e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NFKMLMMI_01599 1.67e-77 ytkC - - S - - - Bacteriophage holin family
NFKMLMMI_01600 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NFKMLMMI_01602 1.66e-96 ytkA - - S - - - YtkA-like
NFKMLMMI_01603 5.89e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NFKMLMMI_01604 5.71e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NFKMLMMI_01605 4.26e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NFKMLMMI_01606 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NFKMLMMI_01607 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NFKMLMMI_01608 1.44e-232 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NFKMLMMI_01609 3.88e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NFKMLMMI_01610 4.21e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NFKMLMMI_01611 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NFKMLMMI_01612 7.22e-198 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NFKMLMMI_01613 2.39e-188 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NFKMLMMI_01614 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NFKMLMMI_01615 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NFKMLMMI_01616 8.57e-160 yteA - - T - - - COG1734 DnaK suppressor protein
NFKMLMMI_01617 5.18e-93 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NFKMLMMI_01639 6.31e-98 yjhE - - S - - - Phage tail protein
NFKMLMMI_01640 2.97e-95 - - - K - - - Integron-associated effector binding protein
NFKMLMMI_01641 9.17e-200 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
NFKMLMMI_01642 1.26e-301 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NFKMLMMI_01643 9.59e-234 mrjp - - G - - - Major royal jelly protein
NFKMLMMI_01644 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NFKMLMMI_01645 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NFKMLMMI_01646 5.77e-56 - - - E - - - Ring-cleavage extradiol dioxygenase
NFKMLMMI_01647 2.86e-83 - - - E - - - Ring-cleavage extradiol dioxygenase
NFKMLMMI_01648 2.58e-86 yxaI - - S - - - membrane protein domain
NFKMLMMI_01649 1.16e-250 - - - EGP - - - Major Facilitator Superfamily
NFKMLMMI_01650 3.34e-65 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NFKMLMMI_01651 5.81e-75 - - - S - - - Family of unknown function (DUF5391)
NFKMLMMI_01652 2.12e-185 yxaL - - S - - - PQQ-like domain
NFKMLMMI_01653 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NFKMLMMI_01654 1.53e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
NFKMLMMI_01655 1.04e-247 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NFKMLMMI_01656 3.16e-243 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_01657 2.06e-129 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFKMLMMI_01658 1.56e-188 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NFKMLMMI_01659 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NFKMLMMI_01660 2.13e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NFKMLMMI_01661 1.72e-215 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NFKMLMMI_01662 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NFKMLMMI_01663 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NFKMLMMI_01664 1.11e-196 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NFKMLMMI_01665 4.09e-224 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NFKMLMMI_01666 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NFKMLMMI_01667 1.73e-218 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NFKMLMMI_01668 2.76e-289 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NFKMLMMI_01669 2.36e-246 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NFKMLMMI_01670 4.92e-209 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NFKMLMMI_01671 6.65e-198 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NFKMLMMI_01672 1.61e-194 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NFKMLMMI_01673 6.33e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_01674 9.27e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_01675 7.1e-177 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_01676 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NFKMLMMI_01677 2.25e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
NFKMLMMI_01678 6.74e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NFKMLMMI_01679 4.86e-47 - - - - - - - -
NFKMLMMI_01680 9.67e-33 yxeD - - - - - - -
NFKMLMMI_01682 9.45e-26 yxeE - - - - - - -
NFKMLMMI_01685 1.75e-188 yxeH - - S - - - hydrolases of the HAD superfamily
NFKMLMMI_01686 9.22e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NFKMLMMI_01687 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NFKMLMMI_01688 1.35e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NFKMLMMI_01689 2.59e-295 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NFKMLMMI_01690 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NFKMLMMI_01691 6.73e-216 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NFKMLMMI_01692 7.66e-291 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NFKMLMMI_01693 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NFKMLMMI_01694 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NFKMLMMI_01695 4.06e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NFKMLMMI_01696 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NFKMLMMI_01697 1.01e-243 - - - S - - - AIPR protein
NFKMLMMI_01698 7.49e-103 - - - S - - - Putative PD-(D/E)XK family member, (DUF4420)
NFKMLMMI_01699 0.0 - - - L - - - Z1 domain
NFKMLMMI_01700 3.55e-204 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
NFKMLMMI_01701 8.04e-176 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NFKMLMMI_01702 1.51e-61 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NFKMLMMI_01703 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_01704 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NFKMLMMI_01705 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
NFKMLMMI_01706 7.42e-202 yxxF - - EG - - - EamA-like transporter family
NFKMLMMI_01707 1.95e-250 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NFKMLMMI_01709 9.79e-75 yxxG - - - - - - -
NFKMLMMI_01710 2.91e-85 yxiG - - - - - - -
NFKMLMMI_01711 4.23e-103 - - - - - - - -
NFKMLMMI_01712 2.79e-140 - - - - - - - -
NFKMLMMI_01714 9.75e-27 - - - - - - - -
NFKMLMMI_01716 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NFKMLMMI_01717 7.88e-277 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NFKMLMMI_01718 2.11e-183 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NFKMLMMI_01719 9.73e-176 bglS - - M - - - licheninase activity
NFKMLMMI_01720 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NFKMLMMI_01721 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NFKMLMMI_01722 3.04e-221 - - - L - - - DNA synthesis involved in DNA repair
NFKMLMMI_01723 3.23e-60 yxiS - - - - - - -
NFKMLMMI_01724 1.64e-113 - - - T - - - Domain of unknown function (DUF4163)
NFKMLMMI_01725 2.49e-262 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NFKMLMMI_01726 2.83e-185 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NFKMLMMI_01727 8.25e-271 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NFKMLMMI_01728 3.81e-105 yxjI - - S - - - LURP-one-related
NFKMLMMI_01731 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NFKMLMMI_01732 7.02e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NFKMLMMI_01733 5.75e-115 yxkC - - S - - - Domain of unknown function (DUF4352)
NFKMLMMI_01735 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NFKMLMMI_01736 1.49e-198 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NFKMLMMI_01737 1.45e-258 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_01738 2.39e-191 yxkH - - G - - - Polysaccharide deacetylase
NFKMLMMI_01739 1.02e-283 cimH - - C - - - COG3493 Na citrate symporter
NFKMLMMI_01740 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NFKMLMMI_01741 5.08e-238 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NFKMLMMI_01742 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NFKMLMMI_01743 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NFKMLMMI_01744 8.69e-192 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NFKMLMMI_01745 2.06e-313 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NFKMLMMI_01746 1.26e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NFKMLMMI_01747 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NFKMLMMI_01748 3.3e-261 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NFKMLMMI_01749 1.23e-226 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NFKMLMMI_01750 6.21e-112 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NFKMLMMI_01751 3.54e-83 - - - L - - - Bacterial transcription activator, effector binding domain
NFKMLMMI_01753 2.06e-297 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NFKMLMMI_01754 5.2e-156 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NFKMLMMI_01755 8.26e-154 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NFKMLMMI_01756 4.03e-315 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NFKMLMMI_01757 4.82e-180 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NFKMLMMI_01758 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NFKMLMMI_01759 6.45e-59 yokU - - S - - - YokU-like protein, putative antitoxin
NFKMLMMI_01760 2.87e-47 yozE - - S - - - Belongs to the UPF0346 family
NFKMLMMI_01761 1.39e-66 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFKMLMMI_01762 1.18e-155 yodN - - - - - - -
NFKMLMMI_01764 1.97e-33 yozD - - S - - - YozD-like protein
NFKMLMMI_01765 8.36e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NFKMLMMI_01766 1.16e-72 yodL - - S - - - YodL-like
NFKMLMMI_01768 4.29e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NFKMLMMI_01769 8.69e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NFKMLMMI_01770 2.3e-30 yodI - - - - - - -
NFKMLMMI_01771 4.97e-156 yodH - - Q - - - Methyltransferase
NFKMLMMI_01772 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NFKMLMMI_01773 3.79e-164 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_01774 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NFKMLMMI_01775 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
NFKMLMMI_01776 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFKMLMMI_01777 1.14e-27 - - - S - - - Protein of unknown function (DUF3311)
NFKMLMMI_01778 5.32e-213 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NFKMLMMI_01779 1.35e-137 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NFKMLMMI_01780 6.14e-135 yodC - - C - - - nitroreductase
NFKMLMMI_01781 1.93e-69 yodB - - K - - - transcriptional
NFKMLMMI_01782 9.37e-83 iolK - - S - - - tautomerase
NFKMLMMI_01784 1.83e-101 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NFKMLMMI_01785 3.04e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NFKMLMMI_01786 3.66e-31 - - - - - - - -
NFKMLMMI_01787 4.69e-79 yojF - - S - - - Protein of unknown function (DUF1806)
NFKMLMMI_01788 2.61e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NFKMLMMI_01789 6.24e-187 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NFKMLMMI_01790 1.51e-297 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NFKMLMMI_01792 3.97e-136 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NFKMLMMI_01793 2.8e-277 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NFKMLMMI_01794 1.68e-276 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NFKMLMMI_01795 1.31e-135 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NFKMLMMI_01796 2e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NFKMLMMI_01797 0.0 yojO - - P - - - Von Willebrand factor
NFKMLMMI_01798 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NFKMLMMI_01799 1.12e-257 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NFKMLMMI_01800 8.69e-156 - - - S - - - Metallo-beta-lactamase superfamily
NFKMLMMI_01801 3.02e-209 yocS - - S ko:K03453 - ko00000 -transporter
NFKMLMMI_01802 2.2e-293 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NFKMLMMI_01803 5.12e-207 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NFKMLMMI_01804 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NFKMLMMI_01805 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NFKMLMMI_01806 4.69e-43 yozC - - - - - - -
NFKMLMMI_01808 5.32e-75 yozO - - S - - - Bacterial PH domain
NFKMLMMI_01809 5.24e-49 yocN - - - - - - -
NFKMLMMI_01810 1.46e-39 yozN - - - - - - -
NFKMLMMI_01811 2.21e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NFKMLMMI_01812 1.16e-11 yocN - - - - - - -
NFKMLMMI_01814 7.44e-78 yocK - - T - - - general stress protein
NFKMLMMI_01815 2.71e-143 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NFKMLMMI_01817 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NFKMLMMI_01818 6.61e-157 yocH - - M - - - COG1388 FOG LysM repeat
NFKMLMMI_01820 8.07e-233 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NFKMLMMI_01821 2.99e-119 yocC - - - - - - -
NFKMLMMI_01822 9.94e-172 - - - J - - - Protein required for attachment to host cells
NFKMLMMI_01823 5.42e-117 yozB - - S ko:K08976 - ko00000 membrane
NFKMLMMI_01824 5.45e-154 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NFKMLMMI_01825 3.14e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NFKMLMMI_01826 1.29e-117 yobW - - - - - - -
NFKMLMMI_01827 1.22e-159 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NFKMLMMI_01828 1.44e-110 yobS - - K - - - Transcriptional regulator
NFKMLMMI_01829 6.26e-156 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NFKMLMMI_01830 2.04e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NFKMLMMI_01833 1.52e-38 - - - - - - - -
NFKMLMMI_01834 6.83e-121 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_01836 6.3e-36 yoaF - - - - - - -
NFKMLMMI_01837 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NFKMLMMI_01838 2.4e-237 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NFKMLMMI_01839 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NFKMLMMI_01840 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NFKMLMMI_01841 3.99e-192 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NFKMLMMI_01842 9.16e-301 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NFKMLMMI_01843 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NFKMLMMI_01844 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NFKMLMMI_01845 7.7e-19 - - - S - - - Uncharacterized protein YkpC
NFKMLMMI_01846 1.63e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NFKMLMMI_01847 4.63e-200 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NFKMLMMI_01848 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NFKMLMMI_01849 3.54e-48 ykoA - - - - - - -
NFKMLMMI_01850 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NFKMLMMI_01851 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NFKMLMMI_01852 8.8e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NFKMLMMI_01853 8.9e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_01854 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NFKMLMMI_01855 3.39e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_01856 4.28e-74 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NFKMLMMI_01857 9.05e-78 - - - K - - - Collagen triple helix repeat
NFKMLMMI_01858 2.15e-260 - - - M - - - Glycosyl transferase family 2
NFKMLMMI_01860 1.46e-70 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NFKMLMMI_01861 1.3e-90 ohrB - - O - - - Organic hydroperoxide resistance protein
NFKMLMMI_01862 6.88e-102 ohrR - - K - - - COG1846 Transcriptional regulators
NFKMLMMI_01863 1.89e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
NFKMLMMI_01864 1.35e-281 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NFKMLMMI_01865 3.28e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NFKMLMMI_01866 1.03e-211 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NFKMLMMI_01867 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NFKMLMMI_01868 8.24e-64 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NFKMLMMI_01869 1.01e-118 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NFKMLMMI_01870 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
NFKMLMMI_01871 1.45e-179 ykgA - - E - - - Amidinotransferase
NFKMLMMI_01872 1.23e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NFKMLMMI_01873 1.49e-227 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_01874 1.74e-198 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NFKMLMMI_01875 2e-244 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NFKMLMMI_01876 8.59e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NFKMLMMI_01877 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NFKMLMMI_01878 1.49e-230 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_01879 3.22e-218 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFKMLMMI_01880 2.68e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFKMLMMI_01881 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NFKMLMMI_01882 0.0 yubD - - P - - - Major Facilitator Superfamily
NFKMLMMI_01883 2.08e-266 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NFKMLMMI_01885 3.02e-227 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NFKMLMMI_01886 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NFKMLMMI_01887 1.75e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NFKMLMMI_01888 2.11e-308 steT - - E ko:K03294 - ko00000 amino acid
NFKMLMMI_01889 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NFKMLMMI_01890 2.36e-224 pit - - P ko:K03306 - ko00000 phosphate transporter
NFKMLMMI_01891 1.05e-169 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NFKMLMMI_01892 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NFKMLMMI_01893 4.2e-207 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NFKMLMMI_01894 7.53e-49 xhlB - - S - - - SPP1 phage holin
NFKMLMMI_01895 6.44e-50 xhlA - - S - - - Haemolysin XhlA
NFKMLMMI_01896 2.97e-167 xepA - - - - - - -
NFKMLMMI_01897 1.05e-36 xkdX - - - - - - -
NFKMLMMI_01899 1.04e-194 - - - - - - - -
NFKMLMMI_01900 1.48e-36 - - - - - - - -
NFKMLMMI_01901 3.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NFKMLMMI_01902 7.54e-203 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NFKMLMMI_01903 9.38e-83 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NFKMLMMI_01904 1.16e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NFKMLMMI_01905 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NFKMLMMI_01906 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NFKMLMMI_01907 5.3e-93 ywoH - - K - - - transcriptional
NFKMLMMI_01908 3.92e-270 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_01909 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NFKMLMMI_01910 1.81e-308 ywoD - - EGP - - - Major facilitator superfamily
NFKMLMMI_01911 2.1e-128 yjgF - - Q - - - Isochorismatase family
NFKMLMMI_01912 3.63e-289 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NFKMLMMI_01913 1.51e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NFKMLMMI_01914 1.11e-262 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NFKMLMMI_01915 5.56e-130 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NFKMLMMI_01916 3.41e-88 ywnJ - - S - - - VanZ like family
NFKMLMMI_01917 1.67e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NFKMLMMI_01918 7.6e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NFKMLMMI_01920 2.45e-88 ywnF - - S - - - Family of unknown function (DUF5392)
NFKMLMMI_01921 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NFKMLMMI_01922 1.12e-21 yqgA - - - - - - -
NFKMLMMI_01923 1.33e-77 ywnC - - S - - - Family of unknown function (DUF5362)
NFKMLMMI_01924 3.75e-116 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NFKMLMMI_01925 3.09e-88 ywnA - - K - - - Transcriptional regulator
NFKMLMMI_01926 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NFKMLMMI_01927 4.37e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NFKMLMMI_01928 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NFKMLMMI_01929 2.21e-15 csbD - - K - - - CsbD-like
NFKMLMMI_01930 1.01e-105 ywmF - - S - - - Peptidase M50
NFKMLMMI_01931 1.44e-114 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NFKMLMMI_01932 2.09e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NFKMLMMI_01933 2.91e-183 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NFKMLMMI_01935 2.79e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NFKMLMMI_01936 4.74e-145 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NFKMLMMI_01937 6.86e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NFKMLMMI_01938 1.85e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NFKMLMMI_01939 2.11e-168 ywmB - - S - - - TATA-box binding
NFKMLMMI_01940 1.85e-44 ywzB - - S - - - membrane
NFKMLMMI_01941 1.98e-115 ywmA - - - - - - -
NFKMLMMI_01942 3.36e-82 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NFKMLMMI_01943 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NFKMLMMI_01944 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NFKMLMMI_01945 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NFKMLMMI_01946 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NFKMLMMI_01947 3.35e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NFKMLMMI_01948 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NFKMLMMI_01949 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NFKMLMMI_01950 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NFKMLMMI_01951 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NFKMLMMI_01952 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NFKMLMMI_01953 3.53e-123 ywlG - - S - - - Belongs to the UPF0340 family
NFKMLMMI_01954 9.2e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NFKMLMMI_01955 1.84e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NFKMLMMI_01956 1.53e-115 mntP - - P - - - Probably functions as a manganese efflux pump
NFKMLMMI_01957 1.34e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NFKMLMMI_01958 6.75e-96 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NFKMLMMI_01959 1.73e-148 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NFKMLMMI_01960 4.04e-77 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NFKMLMMI_01962 8.34e-195 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NFKMLMMI_01963 2.06e-240 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NFKMLMMI_01964 2.93e-85 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFKMLMMI_01965 2.52e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NFKMLMMI_01966 6.87e-194 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NFKMLMMI_01967 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NFKMLMMI_01968 6.49e-131 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NFKMLMMI_01969 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NFKMLMMI_01970 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NFKMLMMI_01971 9.65e-223 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NFKMLMMI_01972 1.59e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NFKMLMMI_01973 3.69e-143 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NFKMLMMI_01974 4.53e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NFKMLMMI_01975 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NFKMLMMI_01976 1.84e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
NFKMLMMI_01977 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NFKMLMMI_01978 1.32e-72 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NFKMLMMI_01979 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NFKMLMMI_01980 1.51e-263 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NFKMLMMI_01981 5.39e-224 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NFKMLMMI_01982 3.23e-58 ywjC - - - - - - -
NFKMLMMI_01983 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NFKMLMMI_01984 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NFKMLMMI_01985 1.61e-149 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NFKMLMMI_01986 1.07e-110 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NFKMLMMI_01987 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NFKMLMMI_01988 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NFKMLMMI_01989 8.63e-102 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NFKMLMMI_01990 8.44e-99 ywiC - - S - - - YwiC-like protein
NFKMLMMI_01991 5.83e-162 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NFKMLMMI_01992 7.56e-267 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NFKMLMMI_01993 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NFKMLMMI_01994 4.46e-94 ywiB - - S - - - protein conserved in bacteria
NFKMLMMI_01996 1.55e-248 ywhL - - CO - - - amine dehydrogenase activity
NFKMLMMI_01997 3.16e-102 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NFKMLMMI_01999 2.87e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NFKMLMMI_02000 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NFKMLMMI_02001 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NFKMLMMI_02002 1.96e-93 - - - - - - - -
NFKMLMMI_02003 2.07e-116 ywhD - - S - - - YwhD family
NFKMLMMI_02004 1.29e-151 ywhC - - S - - - Peptidase family M50
NFKMLMMI_02005 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NFKMLMMI_02006 3.29e-90 ywhA - - K - - - Transcriptional regulator
NFKMLMMI_02007 4.79e-307 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
NFKMLMMI_02008 1.37e-113 ywgA - - - ko:K09388 - ko00000 -
NFKMLMMI_02009 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NFKMLMMI_02010 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NFKMLMMI_02011 3.27e-136 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NFKMLMMI_02012 4.41e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
NFKMLMMI_02013 2.51e-109 - - - S - - - membrane
NFKMLMMI_02014 1.93e-194 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_02015 2.13e-208 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
NFKMLMMI_02018 1.87e-209 - - - - - - - -
NFKMLMMI_02020 8.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NFKMLMMI_02021 1.33e-199 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_02022 1.77e-57 ytrP - - T - - - COG2199 FOG GGDEF domain
NFKMLMMI_02023 2.38e-109 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NFKMLMMI_02024 2.22e-137 yttP - - K - - - Transcriptional regulator
NFKMLMMI_02025 3.79e-183 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NFKMLMMI_02026 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NFKMLMMI_02027 4.41e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NFKMLMMI_02028 3.99e-259 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NFKMLMMI_02029 1.06e-280 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NFKMLMMI_02030 4.15e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NFKMLMMI_02031 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NFKMLMMI_02032 0.0 ytcJ - - S - - - amidohydrolase
NFKMLMMI_02033 1.23e-191 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NFKMLMMI_02034 1.88e-227 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NFKMLMMI_02035 1.31e-103 yteJ - - S - - - RDD family
NFKMLMMI_02036 3.61e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
NFKMLMMI_02037 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
NFKMLMMI_02038 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NFKMLMMI_02039 4.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NFKMLMMI_02040 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NFKMLMMI_02041 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NFKMLMMI_02042 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NFKMLMMI_02043 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NFKMLMMI_02045 1.33e-180 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_02046 2.31e-163 ytkL - - S - - - Belongs to the UPF0173 family
NFKMLMMI_02047 3.87e-303 ytoI - - K - - - transcriptional regulator containing CBS domains
NFKMLMMI_02048 3.44e-60 ytpI - - S - - - YtpI-like protein
NFKMLMMI_02049 7.37e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NFKMLMMI_02050 1.17e-30 - - - - - - - -
NFKMLMMI_02051 3.08e-113 ytrI - - - - - - -
NFKMLMMI_02052 1.12e-71 ytrH - - S - - - Sporulation protein YtrH
NFKMLMMI_02053 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NFKMLMMI_02054 1.92e-283 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NFKMLMMI_02055 2.08e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NFKMLMMI_02056 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NFKMLMMI_02057 1.33e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NFKMLMMI_02058 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NFKMLMMI_02059 1.34e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NFKMLMMI_02060 8.18e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
NFKMLMMI_02061 1.14e-95 ytwI - - S - - - membrane
NFKMLMMI_02062 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NFKMLMMI_02063 1.54e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NFKMLMMI_02064 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NFKMLMMI_02065 2.29e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_02066 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NFKMLMMI_02067 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NFKMLMMI_02068 2.14e-197 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NFKMLMMI_02069 4.52e-135 ytaF - - P - - - Probably functions as a manganese efflux pump
NFKMLMMI_02070 3.15e-123 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NFKMLMMI_02071 4.68e-198 ytbE - - S - - - reductase
NFKMLMMI_02072 2.72e-250 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NFKMLMMI_02073 7.74e-86 ytcD - - K - - - Transcriptional regulator
NFKMLMMI_02074 4.24e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NFKMLMMI_02075 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NFKMLMMI_02076 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NFKMLMMI_02077 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NFKMLMMI_02078 2.64e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NFKMLMMI_02079 1.43e-136 ytxB - - S - - - SNARE associated Golgi protein
NFKMLMMI_02080 6.12e-192 ytxC - - S - - - YtxC-like family
NFKMLMMI_02081 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NFKMLMMI_02082 2.22e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NFKMLMMI_02083 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_02084 8.26e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NFKMLMMI_02085 3.71e-65 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
NFKMLMMI_02086 1.21e-144 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NFKMLMMI_02087 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NFKMLMMI_02088 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NFKMLMMI_02089 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NFKMLMMI_02090 5.91e-51 ysdA - - S - - - Membrane
NFKMLMMI_02091 4.11e-82 ysdB - - S - - - Sigma-w pathway protein YsdB
NFKMLMMI_02092 1.52e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
NFKMLMMI_02093 6.16e-235 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NFKMLMMI_02094 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NFKMLMMI_02095 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NFKMLMMI_02096 1.4e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NFKMLMMI_02097 1.56e-174 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NFKMLMMI_02098 6.32e-05 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NFKMLMMI_02099 4.26e-234 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NFKMLMMI_02100 8.03e-314 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NFKMLMMI_02101 9.46e-210 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
NFKMLMMI_02102 2.11e-78 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NFKMLMMI_02103 3.5e-69 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NFKMLMMI_02105 1.9e-09 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NFKMLMMI_02108 6.63e-135 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NFKMLMMI_02110 5.73e-206 yueF - - S - - - transporter activity
NFKMLMMI_02112 7.27e-73 - - - S - - - YolD-like protein
NFKMLMMI_02113 6.1e-295 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NFKMLMMI_02114 2.7e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NFKMLMMI_02115 1.92e-08 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NFKMLMMI_02116 4.54e-211 yqkA - - K - - - GrpB protein
NFKMLMMI_02117 1.22e-76 yqkB - - S - - - Belongs to the HesB IscA family
NFKMLMMI_02118 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
NFKMLMMI_02119 2.61e-213 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NFKMLMMI_02120 3.06e-15 yqkE - - S - - - Protein of unknown function (DUF3886)
NFKMLMMI_02121 2.34e-211 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NFKMLMMI_02122 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
NFKMLMMI_02123 1.42e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NFKMLMMI_02124 1.43e-271 yqxK - - L - - - DNA helicase
NFKMLMMI_02125 2.32e-75 ansR - - K - - - Transcriptional regulator
NFKMLMMI_02126 4.88e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NFKMLMMI_02127 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NFKMLMMI_02128 3.56e-313 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NFKMLMMI_02129 9.28e-307 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NFKMLMMI_02130 5.05e-33 - - - - - - - -
NFKMLMMI_02131 2.87e-43 yqkK - - - - - - -
NFKMLMMI_02132 4.12e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NFKMLMMI_02133 3.08e-102 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NFKMLMMI_02134 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
NFKMLMMI_02135 1.78e-210 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NFKMLMMI_02136 3.91e-288 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NFKMLMMI_02137 8.69e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NFKMLMMI_02138 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NFKMLMMI_02139 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NFKMLMMI_02140 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NFKMLMMI_02141 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFKMLMMI_02142 9.1e-141 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NFKMLMMI_02143 7.71e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
NFKMLMMI_02144 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NFKMLMMI_02145 9.17e-241 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NFKMLMMI_02146 3.57e-74 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NFKMLMMI_02147 1.2e-138 - - - S ko:K06407 - ko00000 stage V sporulation protein
NFKMLMMI_02148 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NFKMLMMI_02149 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NFKMLMMI_02150 3.35e-194 ypuA - - S - - - Secreted protein
NFKMLMMI_02151 1.18e-103 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NFKMLMMI_02152 6.23e-102 ccdC1 - - O - - - Protein of unknown function (DUF1453)
NFKMLMMI_02153 2.37e-124 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NFKMLMMI_02154 7.86e-68 ypuD - - - - - - -
NFKMLMMI_02155 1.24e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NFKMLMMI_02156 1.09e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NFKMLMMI_02157 8.2e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NFKMLMMI_02158 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NFKMLMMI_02159 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFKMLMMI_02160 2.41e-113 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NFKMLMMI_02162 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NFKMLMMI_02163 1.3e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NFKMLMMI_02164 6.88e-106 ypuI - - S - - - Protein of unknown function (DUF3907)
NFKMLMMI_02165 2.36e-268 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NFKMLMMI_02166 6.22e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NFKMLMMI_02167 7.39e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NFKMLMMI_02168 1.74e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NFKMLMMI_02169 9.77e-125 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NFKMLMMI_02170 8.09e-127 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NFKMLMMI_02171 4.51e-215 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NFKMLMMI_02172 3.09e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NFKMLMMI_02173 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_02174 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_02175 3.09e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NFKMLMMI_02176 6.63e-216 rsiX - - - - - - -
NFKMLMMI_02177 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NFKMLMMI_02178 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NFKMLMMI_02179 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NFKMLMMI_02180 2.97e-244 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NFKMLMMI_02181 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NFKMLMMI_02182 2.24e-124 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NFKMLMMI_02183 8.85e-110 ypbE - - M - - - Lysin motif
NFKMLMMI_02184 3.73e-109 ypbF - - S - - - Protein of unknown function (DUF2663)
NFKMLMMI_02185 5.62e-181 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NFKMLMMI_02186 7.9e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NFKMLMMI_02187 8.6e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NFKMLMMI_02188 5.93e-236 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NFKMLMMI_02189 2.61e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NFKMLMMI_02190 2.15e-203 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NFKMLMMI_02191 1.1e-311 ypeB - - H ko:K06313 - ko00000 sporulation protein
NFKMLMMI_02192 6.58e-72 ypfA - - M - - - Flagellar protein YcgR
NFKMLMMI_02193 1.12e-17 - - - S - - - Family of unknown function (DUF5359)
NFKMLMMI_02194 3.75e-142 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NFKMLMMI_02195 3.17e-261 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NFKMLMMI_02196 4.76e-228 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NFKMLMMI_02197 1.32e-12 - - - S - - - YpzI-like protein
NFKMLMMI_02198 6.38e-129 yphA - - - - - - -
NFKMLMMI_02199 2.86e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NFKMLMMI_02200 9.14e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NFKMLMMI_02201 1.13e-23 yphE - - S - - - Protein of unknown function (DUF2768)
NFKMLMMI_02202 2.47e-166 yphF - - - - - - -
NFKMLMMI_02204 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NFKMLMMI_02205 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NFKMLMMI_02206 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NFKMLMMI_02207 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NFKMLMMI_02208 2.68e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NFKMLMMI_02209 3.03e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NFKMLMMI_02210 5.39e-250 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NFKMLMMI_02211 2.01e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NFKMLMMI_02212 8e-178 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NFKMLMMI_02213 3.26e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NFKMLMMI_02214 1.14e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NFKMLMMI_02215 8.09e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NFKMLMMI_02216 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NFKMLMMI_02217 3.8e-201 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NFKMLMMI_02218 1.15e-158 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NFKMLMMI_02219 2.57e-141 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NFKMLMMI_02220 9.2e-286 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NFKMLMMI_02221 1.08e-175 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NFKMLMMI_02222 2.67e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NFKMLMMI_02223 9.38e-256 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NFKMLMMI_02224 3.79e-290 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NFKMLMMI_02225 7.68e-292 ypiA - - S - - - COG0457 FOG TPR repeat
NFKMLMMI_02226 2.14e-128 ypiB - - S - - - Belongs to the UPF0302 family
NFKMLMMI_02227 1.21e-94 ypiF - - S - - - Protein of unknown function (DUF2487)
NFKMLMMI_02228 9.23e-124 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NFKMLMMI_02229 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NFKMLMMI_02230 9.48e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NFKMLMMI_02231 6.12e-126 ypjA - - S - - - membrane
NFKMLMMI_02232 1.09e-177 ypjB - - S - - - sporulation protein
NFKMLMMI_02233 5.93e-282 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NFKMLMMI_02234 6.13e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NFKMLMMI_02235 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NFKMLMMI_02236 2.7e-131 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NFKMLMMI_02237 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFKMLMMI_02238 1.99e-238 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NFKMLMMI_02239 6.55e-251 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NFKMLMMI_02240 6.01e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NFKMLMMI_02241 6.38e-258 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NFKMLMMI_02242 1.13e-252 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NFKMLMMI_02243 3.44e-200 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NFKMLMMI_02244 4.24e-269 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NFKMLMMI_02245 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NFKMLMMI_02246 7.59e-147 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NFKMLMMI_02247 4.37e-151 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NFKMLMMI_02248 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NFKMLMMI_02249 8.66e-312 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NFKMLMMI_02251 8.3e-111 ywjB - - H - - - RibD C-terminal domain
NFKMLMMI_02252 4.2e-164 - - - CH - - - FAD binding domain
NFKMLMMI_02253 2.74e-98 glx2 - - S - - - Metallo-beta-lactamase superfamily
NFKMLMMI_02254 5.22e-137 yyaS - - S ko:K07149 - ko00000 Membrane
NFKMLMMI_02255 3.65e-108 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFKMLMMI_02256 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NFKMLMMI_02257 1.25e-63 - - - S - - - Protein of unknown function (DUF3237)
NFKMLMMI_02258 3.4e-43 - - - S - - - Protein of unknown function (DUF1433)
NFKMLMMI_02259 1.63e-30 - - - S - - - Protein of unknown function (DUF1433)
NFKMLMMI_02260 6.57e-25 - - - S - - - Protein of unknown function (DUF1433)
NFKMLMMI_02261 2.67e-158 - - - I - - - Pfam Lipase (class 3)
NFKMLMMI_02262 2.88e-120 - - - I - - - Pfam Lipase (class 3)
NFKMLMMI_02263 3.08e-44 - - - - - - - -
NFKMLMMI_02265 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NFKMLMMI_02266 5.05e-279 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
NFKMLMMI_02267 2.68e-226 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NFKMLMMI_02268 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NFKMLMMI_02269 1.4e-202 yraN - - K - - - Transcriptional regulator
NFKMLMMI_02270 3.16e-258 yraM - - S - - - PrpF protein
NFKMLMMI_02271 6.64e-313 - - - EGP - - - Sugar (and other) transporter
NFKMLMMI_02272 1.06e-110 - - - - - - - -
NFKMLMMI_02273 2.87e-132 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NFKMLMMI_02274 5.98e-66 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NFKMLMMI_02275 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NFKMLMMI_02276 8.55e-135 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NFKMLMMI_02277 7.72e-229 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NFKMLMMI_02278 4.11e-100 - - - M - - - Ribonuclease
NFKMLMMI_02279 5.8e-167 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NFKMLMMI_02280 6.52e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NFKMLMMI_02281 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NFKMLMMI_02282 3.01e-224 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NFKMLMMI_02283 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NFKMLMMI_02284 7.32e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NFKMLMMI_02285 6.06e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NFKMLMMI_02286 7.8e-192 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NFKMLMMI_02287 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NFKMLMMI_02288 1.01e-231 sasA - - T - - - Histidine kinase
NFKMLMMI_02289 1.49e-153 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFKMLMMI_02290 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NFKMLMMI_02291 8.74e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NFKMLMMI_02292 4.63e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NFKMLMMI_02293 6.02e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NFKMLMMI_02294 1.75e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NFKMLMMI_02295 6.49e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NFKMLMMI_02296 4.77e-279 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NFKMLMMI_02297 1.45e-145 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NFKMLMMI_02298 9.79e-260 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NFKMLMMI_02299 3.83e-173 yvpB - - NU - - - protein conserved in bacteria
NFKMLMMI_02300 1.2e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NFKMLMMI_02301 3.18e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NFKMLMMI_02302 5.06e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NFKMLMMI_02303 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NFKMLMMI_02304 2.47e-272 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NFKMLMMI_02305 1.44e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NFKMLMMI_02306 2.9e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NFKMLMMI_02307 6.76e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NFKMLMMI_02308 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NFKMLMMI_02309 1.09e-65 yvlD - - S ko:K08972 - ko00000 Membrane
NFKMLMMI_02310 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NFKMLMMI_02311 4.14e-214 yvlB - - S - - - Putative adhesin
NFKMLMMI_02312 1.79e-61 yvlA - - - - - - -
NFKMLMMI_02313 1.29e-40 yvkN - - - - - - -
NFKMLMMI_02314 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NFKMLMMI_02315 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NFKMLMMI_02316 2.59e-45 csbA - - S - - - protein conserved in bacteria
NFKMLMMI_02317 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NFKMLMMI_02318 1.12e-119 yvkB - - K - - - Transcriptional regulator
NFKMLMMI_02319 3.49e-290 yvkA - - P - - - -transporter
NFKMLMMI_02322 1.39e-278 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NFKMLMMI_02323 5.83e-72 swrA - - S - - - Swarming motility protein
NFKMLMMI_02324 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NFKMLMMI_02325 1.35e-271 ywoF - - P - - - Right handed beta helix region
NFKMLMMI_02326 1.48e-196 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NFKMLMMI_02327 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NFKMLMMI_02328 1.47e-58 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NFKMLMMI_02329 5.39e-189 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NFKMLMMI_02330 1.08e-222 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NFKMLMMI_02331 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NFKMLMMI_02332 4.25e-130 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NFKMLMMI_02333 1.92e-89 - - - - - - - -
NFKMLMMI_02334 1.57e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NFKMLMMI_02335 2.18e-83 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NFKMLMMI_02336 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NFKMLMMI_02337 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NFKMLMMI_02338 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NFKMLMMI_02339 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NFKMLMMI_02340 1.27e-104 yviE - - - - - - -
NFKMLMMI_02341 1.63e-206 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NFKMLMMI_02342 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NFKMLMMI_02343 1.43e-101 yvyG - - NOU - - - FlgN protein
NFKMLMMI_02344 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NFKMLMMI_02345 6.15e-95 yvyF - - S - - - flagellar protein
NFKMLMMI_02346 4.91e-79 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NFKMLMMI_02347 2.93e-56 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NFKMLMMI_02348 8.75e-315 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NFKMLMMI_02349 3.16e-197 degV - - S - - - protein conserved in bacteria
NFKMLMMI_02350 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFKMLMMI_02351 3.83e-244 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NFKMLMMI_02352 1.1e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NFKMLMMI_02353 9.24e-234 yvhJ - - K - - - Transcriptional regulator
NFKMLMMI_02354 8.94e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NFKMLMMI_02355 4.55e-285 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NFKMLMMI_02356 2.22e-182 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NFKMLMMI_02357 8.08e-138 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NFKMLMMI_02358 8.4e-317 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NFKMLMMI_02359 5.86e-310 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NFKMLMMI_02360 2.76e-270 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NFKMLMMI_02361 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFKMLMMI_02362 8.51e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NFKMLMMI_02363 5.41e-269 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NFKMLMMI_02364 0.0 lytB - - D - - - Stage II sporulation protein
NFKMLMMI_02365 1.99e-39 - - - - - - - -
NFKMLMMI_02366 1.15e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NFKMLMMI_02367 8.48e-235 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NFKMLMMI_02368 2.14e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NFKMLMMI_02369 1.55e-241 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NFKMLMMI_02370 7.77e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NFKMLMMI_02371 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NFKMLMMI_02372 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
NFKMLMMI_02373 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NFKMLMMI_02374 6.85e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NFKMLMMI_02375 5.65e-258 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NFKMLMMI_02376 2.3e-290 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NFKMLMMI_02377 9.82e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NFKMLMMI_02378 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NFKMLMMI_02379 2.94e-243 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NFKMLMMI_02380 3.1e-218 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NFKMLMMI_02381 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
NFKMLMMI_02382 9.98e-304 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NFKMLMMI_02383 2.02e-223 ywtF_2 - - K - - - Transcriptional regulator
NFKMLMMI_02384 1.33e-195 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NFKMLMMI_02385 1.4e-60 yttA - - S - - - Pfam Transposase IS66
NFKMLMMI_02386 1.37e-288 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NFKMLMMI_02387 1.16e-28 ywtC - - - - - - -
NFKMLMMI_02388 7.41e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NFKMLMMI_02389 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NFKMLMMI_02390 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NFKMLMMI_02391 1.63e-244 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NFKMLMMI_02392 6.95e-228 - - - E - - - Spore germination protein
NFKMLMMI_02393 3.22e-63 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
NFKMLMMI_02394 4.74e-144 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
NFKMLMMI_02395 1.08e-221 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NFKMLMMI_02396 2.47e-195 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NFKMLMMI_02397 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NFKMLMMI_02398 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NFKMLMMI_02399 7.29e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NFKMLMMI_02400 7.75e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NFKMLMMI_02401 6.3e-111 batE - - T - - - Sh3 type 3 domain protein
NFKMLMMI_02402 2.39e-115 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NFKMLMMI_02403 3.56e-185 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NFKMLMMI_02404 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NFKMLMMI_02405 6.98e-211 alsR - - K - - - LysR substrate binding domain
NFKMLMMI_02406 5.9e-297 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NFKMLMMI_02407 8.96e-150 ywrJ - - - - - - -
NFKMLMMI_02408 4.38e-157 cotB - - - ko:K06325 - ko00000 -
NFKMLMMI_02409 9.11e-261 cotH - - M ko:K06330 - ko00000 Spore Coat
NFKMLMMI_02410 4.7e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NFKMLMMI_02412 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NFKMLMMI_02413 3.97e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NFKMLMMI_02414 7.48e-126 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NFKMLMMI_02415 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NFKMLMMI_02416 1.29e-130 - - - - - - - -
NFKMLMMI_02417 7.15e-83 - - - - - - - -
NFKMLMMI_02418 3.77e-97 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
NFKMLMMI_02419 1.92e-25 - - - - - - - -
NFKMLMMI_02420 2.19e-75 - - - S - - - SUKH-4 immunity protein
NFKMLMMI_02421 2.53e-287 ywqJ - - S - - - Pre-toxin TG
NFKMLMMI_02422 1.36e-48 ywqI - - S - - - Family of unknown function (DUF5344)
NFKMLMMI_02424 3.03e-183 ywqG - - S - - - Domain of unknown function (DUF1963)
NFKMLMMI_02425 9.97e-304 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NFKMLMMI_02426 4.63e-176 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NFKMLMMI_02427 3.37e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NFKMLMMI_02428 8.45e-144 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NFKMLMMI_02429 3e-22 - - - - - - - -
NFKMLMMI_02430 0.0 ywqB - - S - - - SWIM zinc finger
NFKMLMMI_02431 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NFKMLMMI_02432 1.28e-193 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NFKMLMMI_02433 2.2e-177 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NFKMLMMI_02434 4.94e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NFKMLMMI_02435 1.83e-74 ywpG - - - - - - -
NFKMLMMI_02436 1.79e-89 ywpF - - S - - - YwpF-like protein
NFKMLMMI_02437 2.54e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NFKMLMMI_02438 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NFKMLMMI_02439 4.41e-247 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NFKMLMMI_02440 1.17e-124 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NFKMLMMI_02441 2.1e-270 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NFKMLMMI_02442 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NFKMLMMI_02443 1.75e-227 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
NFKMLMMI_02444 1.33e-254 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NFKMLMMI_02445 7.16e-284 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NFKMLMMI_02446 1.35e-216 ybaS - - S - - - Na -dependent transporter
NFKMLMMI_02447 4.92e-130 ybbA - - S ko:K07017 - ko00000 Putative esterase
NFKMLMMI_02448 9.92e-223 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_02449 1.48e-224 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_02450 1.12e-215 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NFKMLMMI_02451 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NFKMLMMI_02452 4.44e-291 ybbC - - S - - - protein conserved in bacteria
NFKMLMMI_02453 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NFKMLMMI_02454 6.18e-300 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NFKMLMMI_02455 2.44e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_02456 5.23e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NFKMLMMI_02457 1.13e-76 ybbJ - - J - - - acetyltransferase
NFKMLMMI_02458 5.95e-96 ybbK - - S - - - Protein of unknown function (DUF523)
NFKMLMMI_02464 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NFKMLMMI_02465 1.7e-146 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NFKMLMMI_02466 3.01e-186 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NFKMLMMI_02467 1.1e-291 ybbR - - S - - - protein conserved in bacteria
NFKMLMMI_02468 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NFKMLMMI_02469 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NFKMLMMI_02470 1.17e-21 - - - S - - - peptidyl-tyrosine sulfation
NFKMLMMI_02471 1.28e-221 - - - O - - - growth
NFKMLMMI_02472 5.91e-68 - - - S - - - ABC-2 family transporter protein
NFKMLMMI_02473 3.07e-124 ybdN - - - - - - -
NFKMLMMI_02474 9.57e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
NFKMLMMI_02475 2.34e-203 dkgB - - S - - - Aldo/keto reductase family
NFKMLMMI_02476 3.49e-134 yxaC - - M - - - effector of murein hydrolase
NFKMLMMI_02477 6.65e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NFKMLMMI_02478 1.27e-89 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_02479 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NFKMLMMI_02480 1.67e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NFKMLMMI_02481 7.04e-226 - - - T - - - COG4585 Signal transduction histidine kinase
NFKMLMMI_02482 1.58e-129 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NFKMLMMI_02483 2.13e-205 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NFKMLMMI_02484 1.12e-240 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NFKMLMMI_02485 7.69e-229 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NFKMLMMI_02486 6.5e-33 - - - - - - - -
NFKMLMMI_02487 3.66e-103 - - - S - - - Domain of unknown function (DUF4879)
NFKMLMMI_02488 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NFKMLMMI_02489 2.99e-136 yqeB - - - - - - -
NFKMLMMI_02490 2.17e-52 ybyB - - - - - - -
NFKMLMMI_02491 0.0 ybeC - - E - - - amino acid
NFKMLMMI_02492 1.8e-22 - - - S - - - Protein of unknown function (DUF2651)
NFKMLMMI_02493 2.63e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NFKMLMMI_02494 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NFKMLMMI_02495 1e-23 - - - S - - - Protein of unknown function (DUF2651)
NFKMLMMI_02496 1.12e-261 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
NFKMLMMI_02498 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
NFKMLMMI_02499 5.91e-239 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NFKMLMMI_02500 8.16e-265 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NFKMLMMI_02501 9.04e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NFKMLMMI_02502 3.37e-110 ybfM - - S - - - SNARE associated Golgi protein
NFKMLMMI_02503 4.85e-191 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NFKMLMMI_02504 9.76e-52 ybfN - - - - - - -
NFKMLMMI_02505 4.36e-240 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NFKMLMMI_02506 2.61e-266 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFKMLMMI_02507 6.73e-245 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NFKMLMMI_02508 2.38e-301 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NFKMLMMI_02509 4.63e-225 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NFKMLMMI_02510 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NFKMLMMI_02511 7.21e-90 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NFKMLMMI_02512 4.31e-44 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NFKMLMMI_02513 2.63e-264 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_02514 2.43e-197 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NFKMLMMI_02515 2.31e-158 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
NFKMLMMI_02516 3.3e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NFKMLMMI_02517 3.37e-195 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NFKMLMMI_02518 3.53e-118 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NFKMLMMI_02519 1.04e-93 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NFKMLMMI_02520 1.88e-95 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NFKMLMMI_02521 1.89e-82 ydfP - - S ko:K15977 - ko00000 DoxX
NFKMLMMI_02522 3.11e-73 ydfQ - - CO - - - Thioredoxin
NFKMLMMI_02523 2.08e-15 - - - L - - - COG3666 Transposase and inactivated derivatives
NFKMLMMI_02524 4.68e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
NFKMLMMI_02525 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NFKMLMMI_02526 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NFKMLMMI_02527 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NFKMLMMI_02528 8.33e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NFKMLMMI_02529 1.99e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NFKMLMMI_02530 3.41e-241 ycbU - - E - - - Selenocysteine lyase
NFKMLMMI_02531 1.47e-305 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NFKMLMMI_02532 3.35e-125 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NFKMLMMI_02533 1.19e-58 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NFKMLMMI_02534 5.9e-21 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NFKMLMMI_02535 1.21e-245 yccF - - K ko:K07039 - ko00000 SEC-C motif
NFKMLMMI_02536 6.43e-211 yccK - - C - - - Aldo keto reductase
NFKMLMMI_02537 1.13e-210 ycdA - - S - - - Domain of unknown function (DUF5105)
NFKMLMMI_02538 1.76e-30 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NFKMLMMI_02539 8.16e-249 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NFKMLMMI_02540 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NFKMLMMI_02541 5.55e-116 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NFKMLMMI_02542 3.74e-221 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NFKMLMMI_02543 6.52e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NFKMLMMI_02544 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NFKMLMMI_02545 1.5e-62 - - - S - - - Domain of unknown function (DUF4188)
NFKMLMMI_02546 1.86e-62 - - - K - - - Virulence activator alpha C-term
NFKMLMMI_02547 5.72e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NFKMLMMI_02548 1.15e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NFKMLMMI_02549 1.38e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NFKMLMMI_02550 1.98e-184 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFKMLMMI_02551 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NFKMLMMI_02552 1.84e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NFKMLMMI_02553 1.26e-62 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_02554 3.25e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_02555 1.16e-286 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NFKMLMMI_02556 1.06e-66 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NFKMLMMI_02557 8.85e-212 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NFKMLMMI_02558 9.33e-229 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_02559 7.43e-217 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFKMLMMI_02560 4.07e-139 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NFKMLMMI_02561 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NFKMLMMI_02562 3.67e-65 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NFKMLMMI_02563 1.19e-312 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NFKMLMMI_02564 1.89e-64 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_02565 4.7e-316 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NFKMLMMI_02566 1.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NFKMLMMI_02567 3.02e-244 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NFKMLMMI_02568 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_02569 2.45e-289 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NFKMLMMI_02570 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_02571 3.51e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NFKMLMMI_02572 7.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NFKMLMMI_02573 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NFKMLMMI_02575 2.87e-205 gspA - - M - - - General stress
NFKMLMMI_02576 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NFKMLMMI_02577 8.3e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NFKMLMMI_02578 1.24e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NFKMLMMI_02579 4.69e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NFKMLMMI_02580 1.62e-199 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NFKMLMMI_02581 2.16e-164 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NFKMLMMI_02582 1.52e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NFKMLMMI_02583 6.2e-142 ywbG - - M - - - effector of murein hydrolase
NFKMLMMI_02584 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NFKMLMMI_02585 2.29e-200 ywbI - - K - - - Transcriptional regulator
NFKMLMMI_02586 2.45e-164 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NFKMLMMI_02587 2.72e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NFKMLMMI_02588 2.41e-246 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NFKMLMMI_02589 5.83e-191 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
NFKMLMMI_02590 7.99e-240 - - - K - - - Psort location Cytoplasmic, score
NFKMLMMI_02591 0.0 - - - K - - - Psort location Cytoplasmic, score
NFKMLMMI_02592 9.18e-49 - - - S - - - YolD-like protein
NFKMLMMI_02593 2.46e-57 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NFKMLMMI_02594 4.74e-38 - - - S - - - Bacillus cereus group antimicrobial protein
NFKMLMMI_02598 0.000667 KLHL36 - - T ko:K13958 - ko00000,ko04121 protein modification by small protein conjugation
NFKMLMMI_02599 4.57e-21 - - - N - - - Kelch motif
NFKMLMMI_02601 3.78e-196 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
NFKMLMMI_02602 7.1e-58 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NFKMLMMI_02603 2.24e-301 yfjF - - EGP - - - Belongs to the major facilitator superfamily
NFKMLMMI_02604 1.09e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_02605 7.71e-277 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NFKMLMMI_02606 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NFKMLMMI_02607 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_02608 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NFKMLMMI_02609 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NFKMLMMI_02610 1.67e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
NFKMLMMI_02611 3.81e-45 - - - - - - - -
NFKMLMMI_02612 4.16e-69 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_02613 2.77e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NFKMLMMI_02615 1.07e-28 yjfB - - S - - - Putative motility protein
NFKMLMMI_02616 6.25e-83 yjgA - - T - - - Protein of unknown function (DUF2809)
NFKMLMMI_02617 4.05e-122 yjgB - - S - - - Domain of unknown function (DUF4309)
NFKMLMMI_02618 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NFKMLMMI_02619 5.56e-111 yjgD - - S - - - Protein of unknown function (DUF1641)
NFKMLMMI_02620 7.68e-274 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NFKMLMMI_02621 3.96e-275 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NFKMLMMI_02622 1.73e-40 - - - - - - - -
NFKMLMMI_02623 1.44e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NFKMLMMI_02624 1.72e-150 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NFKMLMMI_02625 4.5e-159 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_02626 5.99e-220 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NFKMLMMI_02627 1.47e-110 yjlB - - S - - - Cupin domain
NFKMLMMI_02628 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NFKMLMMI_02629 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NFKMLMMI_02630 2.92e-80 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NFKMLMMI_02631 3.99e-232 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NFKMLMMI_02632 3.18e-203 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NFKMLMMI_02633 1.29e-112 - - - T - - - Transcriptional regulatory protein, C terminal
NFKMLMMI_02634 3.01e-165 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NFKMLMMI_02636 7.24e-164 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NFKMLMMI_02637 9.4e-100 yjoA - - S - - - DinB family
NFKMLMMI_02638 3.13e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NFKMLMMI_02640 2.62e-60 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NFKMLMMI_02641 9.27e-128 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NFKMLMMI_02642 3.19e-79 yjqA - - S - - - Bacterial PH domain
NFKMLMMI_02643 2.69e-128 yjqB - - S - - - phage-related replication protein
NFKMLMMI_02644 2.86e-139 xkdA - - E - - - IrrE N-terminal-like domain
NFKMLMMI_02645 1.27e-72 xre - - K - - - Helix-turn-helix XRE-family like proteins
NFKMLMMI_02647 8.33e-185 xkdC - - L - - - Bacterial dnaA protein
NFKMLMMI_02651 3.15e-105 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NFKMLMMI_02652 1.37e-139 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
NFKMLMMI_02653 3.35e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
NFKMLMMI_02654 4.94e-302 xkdE3 - - S - - - portal protein
NFKMLMMI_02655 8.47e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
NFKMLMMI_02656 3.38e-202 xkdG - - S - - - Phage capsid family
NFKMLMMI_02657 8.84e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
NFKMLMMI_02659 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
NFKMLMMI_02660 1.82e-75 xkdJ - - - - - - -
NFKMLMMI_02661 3.86e-21 - - - - - - - -
NFKMLMMI_02662 3.64e-284 xkdK - - S - - - Phage tail sheath C-terminal domain
NFKMLMMI_02663 8.21e-97 xkdM - - S - - - Phage tail tube protein
NFKMLMMI_02664 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NFKMLMMI_02665 4.33e-27 - - - - - - - -
NFKMLMMI_02666 7.01e-277 xkdO - - L - - - Transglycosylase SLT domain
NFKMLMMI_02667 2.87e-129 xkdP - - S - - - Lysin motif
NFKMLMMI_02668 2.78e-208 xkdQ - - G - - - NLP P60 protein
NFKMLMMI_02669 3.05e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
NFKMLMMI_02670 2.35e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
NFKMLMMI_02671 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NFKMLMMI_02672 9.72e-229 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NFKMLMMI_02673 9.99e-39 yazB - - K - - - transcriptional
NFKMLMMI_02674 4.38e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NFKMLMMI_02675 1.88e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NFKMLMMI_02676 1.62e-196 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NFKMLMMI_02677 3.18e-191 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NFKMLMMI_02678 5.14e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NFKMLMMI_02679 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NFKMLMMI_02680 1.79e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NFKMLMMI_02681 1.22e-192 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NFKMLMMI_02682 7.52e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NFKMLMMI_02683 6.69e-177 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NFKMLMMI_02684 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NFKMLMMI_02685 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NFKMLMMI_02686 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NFKMLMMI_02687 1.18e-229 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NFKMLMMI_02688 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NFKMLMMI_02689 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NFKMLMMI_02692 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NFKMLMMI_02693 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NFKMLMMI_02694 5.13e-129 yabQ - - S - - - spore cortex biosynthesis protein
NFKMLMMI_02695 5.47e-66 yabP - - S - - - Sporulation protein YabP
NFKMLMMI_02696 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NFKMLMMI_02697 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NFKMLMMI_02698 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFKMLMMI_02699 1.09e-116 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NFKMLMMI_02700 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NFKMLMMI_02701 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
NFKMLMMI_02702 4.99e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NFKMLMMI_02703 1.4e-133 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NFKMLMMI_02704 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NFKMLMMI_02705 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NFKMLMMI_02706 3.49e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NFKMLMMI_02707 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NFKMLMMI_02708 5.43e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NFKMLMMI_02709 2.25e-205 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NFKMLMMI_02710 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
NFKMLMMI_02711 5.32e-53 veg - - S - - - protein conserved in bacteria
NFKMLMMI_02712 1.46e-186 yabG - - S ko:K06436 - ko00000 peptidase
NFKMLMMI_02713 9.41e-200 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NFKMLMMI_02714 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NFKMLMMI_02715 3.55e-288 yabE - - T - - - protein conserved in bacteria
NFKMLMMI_02716 1.44e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NFKMLMMI_02717 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NFKMLMMI_02718 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NFKMLMMI_02719 9.82e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NFKMLMMI_02720 1.64e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NFKMLMMI_02721 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NFKMLMMI_02722 2.53e-55 yabA - - L - - - Involved in initiation control of chromosome replication
NFKMLMMI_02723 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
NFKMLMMI_02724 5.75e-224 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NFKMLMMI_02725 2.86e-92 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NFKMLMMI_02726 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
NFKMLMMI_02727 7.14e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NFKMLMMI_02728 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NFKMLMMI_02729 6.32e-226 yaaN - - P - - - Belongs to the TelA family
NFKMLMMI_02730 1.05e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NFKMLMMI_02731 1.5e-40 csfB - - S - - - Inhibitor of sigma-G Gin
NFKMLMMI_02732 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
NFKMLMMI_02733 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_02734 3.67e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NFKMLMMI_02735 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NFKMLMMI_02736 3.29e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NFKMLMMI_02737 1.29e-40 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NFKMLMMI_02738 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NFKMLMMI_02739 3.32e-302 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NFKMLMMI_02740 7.82e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NFKMLMMI_02741 9.85e-238 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NFKMLMMI_02742 2.95e-239 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NFKMLMMI_02743 2.86e-102 yfjM - - S - - - Psort location Cytoplasmic, score
NFKMLMMI_02744 7.85e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NFKMLMMI_02745 1.83e-60 - - - S - - - YfzA-like protein
NFKMLMMI_02753 0.0 - - - KLT - - - Protein kinase domain
NFKMLMMI_02754 5.62e-307 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NFKMLMMI_02755 3.05e-93 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 Subtilase family
NFKMLMMI_02756 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NFKMLMMI_02757 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NFKMLMMI_02758 5.27e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NFKMLMMI_02760 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NFKMLMMI_02761 2.79e-311 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NFKMLMMI_02762 3.63e-110 ysxD - - - - - - -
NFKMLMMI_02763 8.88e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NFKMLMMI_02764 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NFKMLMMI_02765 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NFKMLMMI_02766 8.92e-291 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NFKMLMMI_02767 1.21e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NFKMLMMI_02768 6.44e-239 ysoA - - H - - - Tetratricopeptide repeat
NFKMLMMI_02769 1.04e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NFKMLMMI_02770 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NFKMLMMI_02771 2.66e-249 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NFKMLMMI_02772 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NFKMLMMI_02773 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NFKMLMMI_02774 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NFKMLMMI_02775 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NFKMLMMI_02780 1.78e-113 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NFKMLMMI_02781 3.07e-129 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NFKMLMMI_02782 2.38e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NFKMLMMI_02783 1.05e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NFKMLMMI_02784 1.06e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NFKMLMMI_02785 7.32e-95 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_02786 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_02787 8.26e-96 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NFKMLMMI_02788 1.77e-188 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NFKMLMMI_02789 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NFKMLMMI_02790 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NFKMLMMI_02791 9.97e-103 yslB - - S - - - Protein of unknown function (DUF2507)
NFKMLMMI_02792 9.22e-270 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NFKMLMMI_02793 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NFKMLMMI_02794 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NFKMLMMI_02795 3.57e-256 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NFKMLMMI_02796 2.04e-45 yppG - - S - - - YppG-like protein
NFKMLMMI_02797 5.45e-79 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NFKMLMMI_02798 6.99e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NFKMLMMI_02799 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NFKMLMMI_02800 3.33e-285 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NFKMLMMI_02802 8.12e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
NFKMLMMI_02803 3.67e-126 ypsA - - S - - - Belongs to the UPF0398 family
NFKMLMMI_02804 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NFKMLMMI_02805 3.07e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NFKMLMMI_02806 2.19e-96 yqgA - - - - - - -
NFKMLMMI_02807 6.91e-31 - - - S - - - YpzG-like protein
NFKMLMMI_02809 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NFKMLMMI_02810 1.95e-186 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NFKMLMMI_02811 1.46e-159 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NFKMLMMI_02812 8.76e-124 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NFKMLMMI_02813 4.64e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
NFKMLMMI_02814 2.2e-09 - - - S - - - Bacillus cereus group antimicrobial protein
NFKMLMMI_02815 8.02e-60 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
NFKMLMMI_02816 2.22e-130 - - - J - - - Acetyltransferase (GNAT) domain
NFKMLMMI_02817 3.81e-254 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NFKMLMMI_02818 2.25e-111 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NFKMLMMI_02819 0.0 ypbR - - S - - - Dynamin family
NFKMLMMI_02820 3e-45 ypbS - - S - - - Protein of unknown function (DUF2533)
NFKMLMMI_02821 5.97e-11 - - - - - - - -
NFKMLMMI_02822 2.07e-204 ypcP - - L - - - 5'3' exonuclease
NFKMLMMI_02824 3.51e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NFKMLMMI_02825 3.96e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NFKMLMMI_02826 4.29e-152 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NFKMLMMI_02827 6.37e-38 ypeQ - - S - - - Zinc-finger
NFKMLMMI_02828 5.37e-48 - - - S - - - Protein of unknown function (DUF2564)
NFKMLMMI_02829 4.27e-16 degR - - - - - - -
NFKMLMMI_02830 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NFKMLMMI_02831 2.89e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NFKMLMMI_02832 1.56e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NFKMLMMI_02834 4.95e-107 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NFKMLMMI_02835 1.69e-116 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NFKMLMMI_02836 8.12e-197 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NFKMLMMI_02837 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NFKMLMMI_02838 1.38e-98 yphP - - S - - - Belongs to the UPF0403 family
NFKMLMMI_02839 2.63e-167 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NFKMLMMI_02840 1.41e-142 ypjP - - S - - - YpjP-like protein
NFKMLMMI_02841 2.08e-202 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NFKMLMMI_02842 6.3e-110 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NFKMLMMI_02843 9.83e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NFKMLMMI_02844 7.14e-141 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NFKMLMMI_02845 1.54e-207 yplP - - K - - - Transcriptional regulator
NFKMLMMI_02846 7.88e-305 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NFKMLMMI_02847 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
NFKMLMMI_02848 2.24e-131 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NFKMLMMI_02849 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NFKMLMMI_02850 2.45e-122 ypmS - - S - - - protein conserved in bacteria
NFKMLMMI_02851 3.91e-88 ypoP - - K - - - transcriptional
NFKMLMMI_02852 1.34e-130 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NFKMLMMI_02853 2.47e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NFKMLMMI_02854 1.29e-129 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NFKMLMMI_02855 6.94e-262 yokA - - L - - - Recombinase
NFKMLMMI_02856 6.05e-22 - - - S - - - Regulatory protein YrvL
NFKMLMMI_02858 5.97e-151 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
NFKMLMMI_02861 5.78e-91 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NFKMLMMI_02862 2.36e-268 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NFKMLMMI_02863 6.45e-215 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NFKMLMMI_02864 1.08e-81 cgeA - - - ko:K06319 - ko00000 -
NFKMLMMI_02865 2.84e-54 cgeC - - - ko:K06321 - ko00000 -
NFKMLMMI_02866 1.17e-286 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NFKMLMMI_02867 4.22e-132 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
NFKMLMMI_02868 1.24e-208 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NFKMLMMI_02869 1.47e-144 ydhC - - K - - - FCD
NFKMLMMI_02870 8.62e-69 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NFKMLMMI_02871 2.15e-102 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NFKMLMMI_02872 5.98e-34 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NFKMLMMI_02874 3.98e-311 pbpE - - V - - - Beta-lactamase
NFKMLMMI_02876 5.02e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
NFKMLMMI_02877 1.24e-244 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NFKMLMMI_02878 3.82e-167 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NFKMLMMI_02879 1.12e-145 - - - K ko:K05799 - ko00000,ko03000 FCD
NFKMLMMI_02880 1.35e-264 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NFKMLMMI_02881 2.88e-63 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NFKMLMMI_02882 4.14e-63 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NFKMLMMI_02883 1.07e-128 yvdT_1 - - K - - - Transcriptional regulator
NFKMLMMI_02884 0.0 ybeC - - E - - - amino acid
NFKMLMMI_02885 4.74e-209 ydhU - - P ko:K07217 - ko00000 Catalase
NFKMLMMI_02886 2.82e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NFKMLMMI_02887 7.98e-228 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NFKMLMMI_02888 4.86e-313 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NFKMLMMI_02891 1.19e-45 - - - K - - - SpoVT / AbrB like domain
NFKMLMMI_02892 1.09e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NFKMLMMI_02893 2e-154 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NFKMLMMI_02894 6.53e-167 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
NFKMLMMI_02895 1.62e-44 - - - - - - - -
NFKMLMMI_02896 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NFKMLMMI_02897 1.05e-50 spoVIF - - S - - - Stage VI sporulation protein F
NFKMLMMI_02898 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NFKMLMMI_02901 1.69e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
NFKMLMMI_02902 4.61e-69 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
NFKMLMMI_02903 1.02e-36 cotW - - - ko:K06341 - ko00000 -
NFKMLMMI_02904 3.55e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NFKMLMMI_02905 1.75e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NFKMLMMI_02906 3.35e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NFKMLMMI_02907 2.47e-100 yjbX - - S - - - Spore coat protein
NFKMLMMI_02908 1.38e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NFKMLMMI_02909 2.99e-180 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NFKMLMMI_02910 1.17e-226 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NFKMLMMI_02911 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NFKMLMMI_02912 5.3e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
NFKMLMMI_02913 8.33e-255 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NFKMLMMI_02914 2.91e-132 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NFKMLMMI_02915 2.06e-170 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NFKMLMMI_02916 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NFKMLMMI_02917 2.39e-102 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NFKMLMMI_02918 5.9e-61 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NFKMLMMI_02919 2.7e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NFKMLMMI_02920 6.92e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NFKMLMMI_02921 3.67e-138 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NFKMLMMI_02922 3.37e-79 yjbL - - S - - - Belongs to the UPF0738 family
NFKMLMMI_02923 8.1e-118 yjbK - - S - - - protein conserved in bacteria
NFKMLMMI_02924 1.15e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NFKMLMMI_02925 6.79e-91 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NFKMLMMI_02926 9.23e-215 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NFKMLMMI_02927 3.14e-27 - - - - - - - -
NFKMLMMI_02928 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NFKMLMMI_02929 1.14e-256 coiA - - S ko:K06198 - ko00000 Competence protein
NFKMLMMI_02930 2.3e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NFKMLMMI_02931 2.28e-140 yjbE - - P - - - Integral membrane protein TerC family
NFKMLMMI_02932 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NFKMLMMI_02933 1.04e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFKMLMMI_02934 3.04e-280 - - - S - - - Putative glycosyl hydrolase domain
NFKMLMMI_02935 5.27e-139 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NFKMLMMI_02937 4.72e-217 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NFKMLMMI_02939 2.08e-54 - - - S - - - dUTPase
NFKMLMMI_02942 2.62e-08 - - - S - - - YopX protein
NFKMLMMI_02947 3.27e-63 - - - - - - - -
NFKMLMMI_02949 1.76e-22 - - - V - - - VanZ like family
NFKMLMMI_02950 5.88e-88 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NFKMLMMI_02952 1.74e-17 - - - K - - - Transcriptional regulator
NFKMLMMI_02955 7.49e-103 yqaS - - L - - - DNA packaging
NFKMLMMI_02956 9.66e-225 - - - S - - - Pfam:Terminase_3C
NFKMLMMI_02957 9.32e-157 - - - S - - - Phage portal protein, SPP1 Gp6-like
NFKMLMMI_02958 1.53e-116 - - - S - - - Phage Mu protein F like protein
NFKMLMMI_02960 3.82e-56 - - - S - - - Phage minor structural protein GP20
NFKMLMMI_02961 1.85e-61 - - - S - - - viral capsid
NFKMLMMI_02964 2.05e-36 - - - S - - - Phage gp6-like head-tail connector protein
NFKMLMMI_02965 7.37e-38 - - - S - - - Phage head-tail joining protein
NFKMLMMI_02966 1.29e-49 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NFKMLMMI_02967 1.14e-37 - - - S - - - Protein of unknown function (DUF3168)
NFKMLMMI_02968 1.3e-43 - - - S - - - Phage tail tube protein
NFKMLMMI_02970 8.44e-187 - - - - - - - -
NFKMLMMI_02973 2.51e-246 - - - L - - - Phage minor structural protein
NFKMLMMI_02977 1.19e-40 xhlA - - S - - - Haemolysin XhlA
NFKMLMMI_02978 2.07e-37 xhlB - - S - - - SPP1 phage holin
NFKMLMMI_02979 5.73e-155 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NFKMLMMI_02982 4.64e-155 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NFKMLMMI_02983 5.48e-314 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NFKMLMMI_02984 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NFKMLMMI_02985 4.22e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NFKMLMMI_02986 1.26e-156 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NFKMLMMI_02987 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
NFKMLMMI_02988 5.39e-252 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NFKMLMMI_02989 1.44e-171 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NFKMLMMI_02990 6.85e-192 nodB1 - - G - - - deacetylase
NFKMLMMI_02991 1.05e-191 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NFKMLMMI_02992 9.13e-126 pksA - - K - - - Transcriptional regulator
NFKMLMMI_02993 1.17e-118 ymcC - - S - - - Membrane
NFKMLMMI_02994 3.96e-107 - - - T - - - universal stress protein
NFKMLMMI_02995 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NFKMLMMI_02996 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NFKMLMMI_02997 9.64e-127 yheG - - GM - - - NAD(P)H-binding
NFKMLMMI_02999 3.86e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NFKMLMMI_03000 3.53e-48 yheE - - S - - - Family of unknown function (DUF5342)
NFKMLMMI_03001 5.52e-316 yheD - - HJ - - - YheC/D like ATP-grasp
NFKMLMMI_03002 2.7e-257 yheC - - HJ - - - YheC/D like ATP-grasp
NFKMLMMI_03003 3.13e-254 yheB - - S - - - Belongs to the UPF0754 family
NFKMLMMI_03004 5.48e-69 yheA - - S - - - Belongs to the UPF0342 family
NFKMLMMI_03005 2.49e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NFKMLMMI_03006 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NFKMLMMI_03007 1.48e-311 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
NFKMLMMI_03008 9.07e-263 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NFKMLMMI_03009 6.25e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NFKMLMMI_03011 4.59e-172 yhaR - - I - - - enoyl-CoA hydratase
NFKMLMMI_03012 1.21e-20 - - - S - - - YhzD-like protein
NFKMLMMI_03013 3.45e-209 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_03014 2.67e-274 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NFKMLMMI_03016 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NFKMLMMI_03017 7.86e-82 yfiD3 - - S - - - DoxX
NFKMLMMI_03018 5.91e-199 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NFKMLMMI_03019 2.12e-99 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NFKMLMMI_03020 1.49e-89 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NFKMLMMI_03021 1e-119 padR - - K - - - transcriptional
NFKMLMMI_03022 1.83e-128 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NFKMLMMI_03023 2.39e-223 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NFKMLMMI_03024 1.37e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NFKMLMMI_03025 2.04e-122 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NFKMLMMI_03026 0.0 yfiU - - EGP - - - the major facilitator superfamily
NFKMLMMI_03027 2.11e-103 yfiV - - K - - - transcriptional
NFKMLMMI_03028 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NFKMLMMI_03029 1.27e-193 yfhB - - S - - - PhzF family
NFKMLMMI_03030 3.09e-133 yfhC - - C - - - nitroreductase
NFKMLMMI_03031 6.01e-33 yfhD - - S - - - YfhD-like protein
NFKMLMMI_03033 3.2e-210 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NFKMLMMI_03034 1.95e-177 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NFKMLMMI_03035 3.93e-61 yfhH - - S - - - Protein of unknown function (DUF1811)
NFKMLMMI_03036 6.7e-231 yfhI - - EGP - - - -transporter
NFKMLMMI_03038 6.62e-203 mpr - - M - - - Belongs to the peptidase S1B family
NFKMLMMI_03039 4.27e-58 yfhJ - - S - - - WVELL protein
NFKMLMMI_03040 2.3e-112 yfhK - - T - - - Bacterial SH3 domain homologues
NFKMLMMI_03041 1.7e-47 yfhL - - S - - - SdpI/YhfL protein family
NFKMLMMI_03042 5.37e-156 - - - S - - - Alpha/beta hydrolase family
NFKMLMMI_03043 1.29e-234 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NFKMLMMI_03044 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NFKMLMMI_03045 4.29e-229 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NFKMLMMI_03046 3.84e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NFKMLMMI_03047 1.47e-49 yfhS - - - - - - -
NFKMLMMI_03048 1.73e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_03049 9.58e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NFKMLMMI_03050 1.4e-49 ygaB - - S - - - YgaB-like protein
NFKMLMMI_03051 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NFKMLMMI_03052 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NFKMLMMI_03053 1.76e-237 ygaE - - S - - - Membrane
NFKMLMMI_03054 1.27e-309 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NFKMLMMI_03055 7.73e-109 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NFKMLMMI_03056 6.8e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NFKMLMMI_03057 1.1e-73 ygzB - - S - - - UPF0295 protein
NFKMLMMI_03058 2.08e-208 ygxA - - S - - - Nucleotidyltransferase-like
NFKMLMMI_03060 3.16e-97 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_03061 0.0 mdr - - EGP - - - the major facilitator superfamily
NFKMLMMI_03062 1.55e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NFKMLMMI_03063 2.85e-15 - - - S - - - RDD family
NFKMLMMI_03064 1.04e-53 ycgB - - - - - - -
NFKMLMMI_03065 9.33e-31 ycgA - - S - - - Membrane
NFKMLMMI_03066 2.88e-238 ycgA - - S - - - Membrane
NFKMLMMI_03067 6.41e-261 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NFKMLMMI_03068 4.54e-207 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NFKMLMMI_03069 2.01e-184 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NFKMLMMI_03070 8.61e-291 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NFKMLMMI_03072 2.43e-265 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NFKMLMMI_03073 1.36e-245 yceH - - P - - - Belongs to the TelA family
NFKMLMMI_03074 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NFKMLMMI_03075 4.28e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NFKMLMMI_03076 3.36e-136 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NFKMLMMI_03077 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NFKMLMMI_03078 9.56e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NFKMLMMI_03079 1.45e-107 ykyB - - S - - - YkyB-like protein
NFKMLMMI_03080 8.16e-302 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_03081 3.48e-114 ykuD - - S - - - protein conserved in bacteria
NFKMLMMI_03082 7.29e-188 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NFKMLMMI_03083 1.33e-175 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_03085 1.74e-293 ykuI - - T - - - Diguanylate phosphodiesterase
NFKMLMMI_03086 2.11e-49 ykuJ - - S - - - protein conserved in bacteria
NFKMLMMI_03087 6.94e-117 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
NFKMLMMI_03088 2.63e-36 ykzF - - S - - - Antirepressor AbbA
NFKMLMMI_03089 8.55e-99 ykuL - - S - - - CBS domain
NFKMLMMI_03090 1.08e-214 ccpC - - K - - - Transcriptional regulator
NFKMLMMI_03091 2.92e-113 ykuN - - C ko:K03839 - ko00000 Flavodoxin
NFKMLMMI_03092 1.07e-207 ykuO - - - - - - -
NFKMLMMI_03093 2.61e-95 fld - - C ko:K03839 - ko00000 Flavodoxin
NFKMLMMI_03094 4.79e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NFKMLMMI_03095 8.58e-271 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NFKMLMMI_03096 1.25e-51 ykuS - - S - - - Belongs to the UPF0180 family
NFKMLMMI_03097 5.77e-177 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NFKMLMMI_03099 1.9e-93 ykuV - - CO - - - thiol-disulfide
NFKMLMMI_03101 3.55e-125 rok - - K - - - Repressor of ComK
NFKMLMMI_03102 8.39e-201 yknT - - - ko:K06437 - ko00000 -
NFKMLMMI_03103 3.85e-130 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NFKMLMMI_03104 1.45e-233 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NFKMLMMI_03105 7.3e-305 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NFKMLMMI_03106 3.06e-111 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NFKMLMMI_03107 1.19e-107 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NFKMLMMI_03108 4.7e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NFKMLMMI_03109 5.77e-134 yknW - - S - - - Yip1 domain
NFKMLMMI_03110 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NFKMLMMI_03111 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NFKMLMMI_03112 1.59e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NFKMLMMI_03113 6.11e-231 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NFKMLMMI_03114 7.98e-156 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NFKMLMMI_03115 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFKMLMMI_03116 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NFKMLMMI_03117 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NFKMLMMI_03118 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NFKMLMMI_03119 1.01e-189 yerO - - K - - - Transcriptional regulator
NFKMLMMI_03120 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NFKMLMMI_03121 8.56e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NFKMLMMI_03122 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NFKMLMMI_03123 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NFKMLMMI_03124 2.88e-204 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NFKMLMMI_03125 3.92e-175 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NFKMLMMI_03126 5.92e-51 - - - S - - - Protein of unknown function, DUF600
NFKMLMMI_03127 2.35e-73 - - - S - - - Protein of unknown function, DUF600
NFKMLMMI_03128 2.48e-66 - - - S - - - Protein of unknown function, DUF600
NFKMLMMI_03129 1.69e-257 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
NFKMLMMI_03130 6.14e-152 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
NFKMLMMI_03131 4.43e-162 yeeN - - K - - - transcriptional regulatory protein
NFKMLMMI_03133 2.48e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NFKMLMMI_03134 1.32e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NFKMLMMI_03135 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
NFKMLMMI_03136 4.26e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NFKMLMMI_03137 1.38e-114 yesJ - - K - - - Acetyltransferase (GNAT) family
NFKMLMMI_03139 1.26e-147 yetF - - S - - - membrane
NFKMLMMI_03140 3.06e-70 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NFKMLMMI_03141 2.87e-82 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFKMLMMI_03142 2.4e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NFKMLMMI_03143 7.84e-29 - - - S - - - Uncharacterized small protein (DUF2292)
NFKMLMMI_03144 2.59e-73 - - - H - - - riboflavin kinase activity
NFKMLMMI_03145 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NFKMLMMI_03146 3.05e-110 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NFKMLMMI_03147 3.35e-246 yetM - - CH - - - FAD binding domain
NFKMLMMI_03148 2.78e-251 yetN - - S - - - Protein of unknown function (DUF3900)
NFKMLMMI_03150 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
NFKMLMMI_03152 1.57e-71 - - - S - - - Protein of unknown function (DUF1064)
NFKMLMMI_03153 5.52e-28 - - - S - - - YopX protein
NFKMLMMI_03155 1.54e-152 yqaM - - L - - - IstB-like ATP binding protein
NFKMLMMI_03156 4.55e-36 yqaL - - L - - - DnaD domain protein
NFKMLMMI_03157 9.65e-162 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NFKMLMMI_03158 1.09e-192 yqaJ - - L - - - YqaJ-like viral recombinase domain
NFKMLMMI_03162 3.27e-110 - - - - - - - -
NFKMLMMI_03163 4.76e-76 - - - S - - - DNA binding
NFKMLMMI_03164 2.39e-48 - - - - - - - -
NFKMLMMI_03165 1.73e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
NFKMLMMI_03166 3.22e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
NFKMLMMI_03167 8.41e-82 - - - - - - - -
NFKMLMMI_03168 4.09e-50 - - - S - - - Protein of unknown function (DUF4064)
NFKMLMMI_03169 3.68e-35 xkdA - - E - - - IrrE N-terminal-like domain
NFKMLMMI_03170 1.16e-43 - - - L - - - Arm DNA-binding domain
NFKMLMMI_03171 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NFKMLMMI_03172 3.86e-260 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NFKMLMMI_03173 5.27e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NFKMLMMI_03174 1.53e-191 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NFKMLMMI_03175 0.0 bkdR - - KT - - - Transcriptional regulator
NFKMLMMI_03176 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
NFKMLMMI_03177 7.1e-199 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NFKMLMMI_03178 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NFKMLMMI_03179 9.85e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NFKMLMMI_03180 9.44e-109 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NFKMLMMI_03181 1.94e-125 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NFKMLMMI_03182 1.86e-185 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NFKMLMMI_03183 7.97e-186 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NFKMLMMI_03184 1.59e-62 yuzC - - - - - - -
NFKMLMMI_03185 1.87e-11 - - - S - - - DegQ (SacQ) family
NFKMLMMI_03186 5.91e-78 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
NFKMLMMI_03188 2.74e-314 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_03189 3.29e-147 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFKMLMMI_03190 3.55e-77 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NFKMLMMI_03191 8.16e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NFKMLMMI_03192 2.15e-49 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFKMLMMI_03193 1.13e-97 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFKMLMMI_03194 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFKMLMMI_03195 1.42e-65 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFKMLMMI_03196 8.6e-88 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFKMLMMI_03197 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NFKMLMMI_03199 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NFKMLMMI_03200 1.68e-232 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NFKMLMMI_03201 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_03202 7.9e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NFKMLMMI_03203 3.8e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NFKMLMMI_03204 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NFKMLMMI_03205 2.08e-97 yufK - - S - - - Family of unknown function (DUF5366)
NFKMLMMI_03206 5.95e-92 yuxK - - S - - - protein conserved in bacteria
NFKMLMMI_03207 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NFKMLMMI_03208 2.83e-47 yuxJ - - EGP - - - Major facilitator superfamily
NFKMLMMI_03209 9.91e-217 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NFKMLMMI_03210 2.23e-73 - - - S - - - phosphoglycolate phosphatase activity
NFKMLMMI_03211 7.05e-215 yunF - - S - - - Protein of unknown function DUF72
NFKMLMMI_03212 5.58e-182 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NFKMLMMI_03213 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NFKMLMMI_03214 1.53e-164 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NFKMLMMI_03215 1.26e-245 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NFKMLMMI_03216 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NFKMLMMI_03217 3.71e-62 yutD - - S - - - protein conserved in bacteria
NFKMLMMI_03218 3e-93 yutE - - S - - - Protein of unknown function DUF86
NFKMLMMI_03219 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NFKMLMMI_03220 1.07e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NFKMLMMI_03221 5.56e-244 yutH - - S - - - Spore coat protein
NFKMLMMI_03222 1.37e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NFKMLMMI_03223 3.65e-248 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NFKMLMMI_03224 2.22e-206 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NFKMLMMI_03225 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NFKMLMMI_03226 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NFKMLMMI_03227 2.61e-70 yuzD - - S - - - protein conserved in bacteria
NFKMLMMI_03228 7.79e-262 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NFKMLMMI_03229 4.81e-50 yuzB - - S - - - Belongs to the UPF0349 family
NFKMLMMI_03230 1e-160 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NFKMLMMI_03231 2.26e-129 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NFKMLMMI_03232 2.6e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NFKMLMMI_03233 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NFKMLMMI_03234 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NFKMLMMI_03235 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NFKMLMMI_03236 2.73e-247 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_03237 5.61e-139 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFKMLMMI_03238 2.89e-108 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NFKMLMMI_03239 1.16e-51 yhdB - - S - - - YhdB-like protein
NFKMLMMI_03240 2.33e-68 yhdC - - S - - - Protein of unknown function (DUF3889)
NFKMLMMI_03241 1.73e-35 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NFKMLMMI_03242 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
NFKMLMMI_03243 2.84e-123 tnpR - - L - - - resolvase
NFKMLMMI_03244 4.04e-103 - - - - - - - -
NFKMLMMI_03246 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
NFKMLMMI_03247 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NFKMLMMI_03248 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NFKMLMMI_03249 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NFKMLMMI_03250 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
NFKMLMMI_03251 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
NFKMLMMI_03252 2.29e-192 - - - S - - - membrane
NFKMLMMI_03253 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
NFKMLMMI_03254 0.0 - - - I - - - PLD-like domain
NFKMLMMI_03255 1.16e-120 - - - S - - - Protein of unknown function (DUF421)
NFKMLMMI_03256 1.8e-152 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NFKMLMMI_03257 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NFKMLMMI_03258 1.11e-273 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NFKMLMMI_03259 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NFKMLMMI_03260 1.37e-98 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NFKMLMMI_03261 2.23e-149 yuiC - - S - - - protein conserved in bacteria
NFKMLMMI_03262 1.21e-45 yuiB - - S - - - Putative membrane protein
NFKMLMMI_03263 3.83e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NFKMLMMI_03264 1.15e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NFKMLMMI_03266 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NFKMLMMI_03267 1.57e-37 - - - - - - - -
NFKMLMMI_03268 1.09e-86 - - - CP - - - Membrane
NFKMLMMI_03269 1.41e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NFKMLMMI_03271 1.25e-42 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
NFKMLMMI_03273 5.08e-55 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NFKMLMMI_03274 6e-167 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NFKMLMMI_03275 1.88e-80 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NFKMLMMI_03276 1.46e-203 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NFKMLMMI_03277 2.78e-138 eSD - - S ko:K07017 - ko00000 Putative esterase
NFKMLMMI_03278 5.34e-166 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NFKMLMMI_03279 7.09e-273 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NFKMLMMI_03280 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NFKMLMMI_03281 5.68e-208 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NFKMLMMI_03282 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_03283 3.6e-42 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NFKMLMMI_03284 2.71e-165 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NFKMLMMI_03285 9.05e-258 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NFKMLMMI_03286 1.66e-288 yukF - - QT - - - Transcriptional regulator
NFKMLMMI_03287 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
NFKMLMMI_03288 8.78e-52 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NFKMLMMI_03289 2.45e-261 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NFKMLMMI_03290 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NFKMLMMI_03291 0.0 yueB - - S - - - type VII secretion protein EsaA
NFKMLMMI_03292 4.27e-97 yueC - - S - - - Family of unknown function (DUF5383)
NFKMLMMI_03293 2.35e-159 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_03294 1.83e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NFKMLMMI_03295 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
NFKMLMMI_03296 2.31e-232 yueF - - S - - - transporter activity
NFKMLMMI_03297 4.3e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NFKMLMMI_03298 1.1e-50 yueH - - S - - - YueH-like protein
NFKMLMMI_03299 4.96e-86 yueI - - S - - - Protein of unknown function (DUF1694)
NFKMLMMI_03300 4.46e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NFKMLMMI_03301 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NFKMLMMI_03302 1.12e-285 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NFKMLMMI_03303 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NFKMLMMI_03304 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NFKMLMMI_03305 2.21e-19 - - - - - - - -
NFKMLMMI_03306 2.04e-60 ynfC - - - - - - -
NFKMLMMI_03307 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NFKMLMMI_03308 1.56e-28 yndG - - S - - - DoxX-like family
NFKMLMMI_03309 2.24e-99 - - - S - - - Domain of unknown function (DUF4166)
NFKMLMMI_03310 0.0 yndJ - - S - - - YndJ-like protein
NFKMLMMI_03311 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
NFKMLMMI_03312 3.49e-282 - - - T - - - Histidine kinase
NFKMLMMI_03313 1.84e-155 - - - T - - - Transcriptional regulatory protein, C terminal
NFKMLMMI_03314 2.01e-303 - 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
NFKMLMMI_03315 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NFKMLMMI_03316 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_03317 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_03318 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_03319 3.84e-262 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NFKMLMMI_03320 1.26e-156 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NFKMLMMI_03321 5.28e-135 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NFKMLMMI_03322 2.32e-145 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NFKMLMMI_03323 6.2e-207 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NFKMLMMI_03324 4.21e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NFKMLMMI_03325 7.37e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NFKMLMMI_03326 3.12e-254 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NFKMLMMI_03327 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NFKMLMMI_03328 8.22e-171 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NFKMLMMI_03329 1.02e-88 yngA - - S - - - membrane
NFKMLMMI_03330 1.01e-196 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NFKMLMMI_03331 6.22e-134 yngC - - S - - - SNARE associated Golgi protein
NFKMLMMI_03332 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NFKMLMMI_03333 2.97e-170 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NFKMLMMI_03334 3.73e-209 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NFKMLMMI_03335 2.28e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NFKMLMMI_03336 6.49e-304 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NFKMLMMI_03337 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NFKMLMMI_03338 2.84e-263 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NFKMLMMI_03339 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NFKMLMMI_03340 5.39e-82 yngL - - S - - - Protein of unknown function (DUF1360)
NFKMLMMI_03341 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
NFKMLMMI_03342 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_03343 1.04e-105 stoA - - CO - - - thiol-disulfide
NFKMLMMI_03344 1.16e-300 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFKMLMMI_03345 5.23e-136 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NFKMLMMI_03346 8.76e-38 - - - - - - - -
NFKMLMMI_03347 1.56e-34 ykvS - - S - - - protein conserved in bacteria
NFKMLMMI_03348 6.76e-56 ykvR - - S - - - Protein of unknown function (DUF3219)
NFKMLMMI_03349 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NFKMLMMI_03350 1.98e-176 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NFKMLMMI_03351 2.55e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NFKMLMMI_03352 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NFKMLMMI_03353 1.81e-196 - - - - - - - -
NFKMLMMI_03355 6.18e-222 ykvI - - S - - - membrane
NFKMLMMI_03356 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NFKMLMMI_03357 5.97e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NFKMLMMI_03358 9.75e-159 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NFKMLMMI_03359 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NFKMLMMI_03360 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NFKMLMMI_03362 7.7e-117 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NFKMLMMI_03363 9.6e-141 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NFKMLMMI_03364 1.45e-169 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NFKMLMMI_03365 4.16e-284 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NFKMLMMI_03366 1.52e-283 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NFKMLMMI_03367 1.03e-175 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NFKMLMMI_03368 9.79e-278 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NFKMLMMI_03369 1.59e-244 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NFKMLMMI_03371 9.18e-105 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NFKMLMMI_03372 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_03373 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NFKMLMMI_03374 1.37e-26 ykzE - - - - - - -
NFKMLMMI_03375 2.76e-144 - - - S - - - Protein of unknown function (DUF421)
NFKMLMMI_03376 7.83e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NFKMLMMI_03377 1.74e-197 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NFKMLMMI_03378 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
NFKMLMMI_03379 3.31e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NFKMLMMI_03380 1.17e-219 ykrI - - S - - - Anti-sigma factor N-terminus
NFKMLMMI_03381 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFKMLMMI_03382 5.75e-164 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NFKMLMMI_03383 1.21e-123 ykoX - - S - - - membrane-associated protein
NFKMLMMI_03384 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
NFKMLMMI_03385 1.82e-197 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NFKMLMMI_03386 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NFKMLMMI_03387 2.57e-127 ykoP - - G - - - polysaccharide deacetylase
NFKMLMMI_03388 3.16e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NFKMLMMI_03389 3.57e-35 ykoL - - - - - - -
NFKMLMMI_03390 2.24e-23 - - - - - - - -
NFKMLMMI_03391 3.53e-69 tnrA - - K - - - transcriptional
NFKMLMMI_03392 7.93e-306 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NFKMLMMI_03394 5.3e-302 ydhD - - M - - - Glycosyl hydrolase
NFKMLMMI_03395 3.67e-123 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NFKMLMMI_03396 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_03397 7.49e-161 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NFKMLMMI_03398 2.08e-179 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NFKMLMMI_03399 2.76e-221 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NFKMLMMI_03400 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NFKMLMMI_03401 7.17e-152 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NFKMLMMI_03402 5.93e-263 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_03403 1.13e-51 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NFKMLMMI_03404 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NFKMLMMI_03405 7.99e-37 yfjT - - - - - - -
NFKMLMMI_03406 9.38e-279 yfkA - - S - - - YfkB-like domain
NFKMLMMI_03407 5.34e-182 yfkC - - M - - - Mechanosensitive ion channel
NFKMLMMI_03408 4.99e-180 yfkD - - S - - - YfkD-like protein
NFKMLMMI_03409 5.21e-233 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NFKMLMMI_03410 1.55e-273 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_03411 8.85e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NFKMLMMI_03412 2.71e-63 yfkI - - S - - - gas vesicle protein
NFKMLMMI_03413 1.38e-102 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NFKMLMMI_03414 1.28e-39 yfkK - - S - - - Belongs to the UPF0435 family
NFKMLMMI_03415 3.66e-23 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_03416 1.42e-199 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_03417 5.75e-165 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NFKMLMMI_03418 1.61e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NFKMLMMI_03419 2.99e-228 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NFKMLMMI_03420 4.01e-115 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NFKMLMMI_03421 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NFKMLMMI_03422 5.49e-235 yibE - - S - - - YibE/F-like protein
NFKMLMMI_03423 8.73e-160 yibF - - S - - - YibE/F-like protein
NFKMLMMI_03424 1.34e-154 frp - - C - - - nitroreductase
NFKMLMMI_03425 2.03e-162 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NFKMLMMI_03426 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NFKMLMMI_03427 1.5e-311 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_03428 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
NFKMLMMI_03429 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
NFKMLMMI_03430 2.68e-100 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NFKMLMMI_03431 3.87e-80 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NFKMLMMI_03432 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NFKMLMMI_03433 8.21e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NFKMLMMI_03434 8.21e-259 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NFKMLMMI_03435 7.69e-254 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NFKMLMMI_03436 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NFKMLMMI_03437 8.42e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
NFKMLMMI_03438 1.3e-29 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NFKMLMMI_03439 2.27e-71 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NFKMLMMI_03440 8.28e-178 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NFKMLMMI_03441 5.48e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NFKMLMMI_03442 7.32e-144 yqxM - - - ko:K19433 - ko00000 -
NFKMLMMI_03443 3.98e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
NFKMLMMI_03444 9.56e-35 yqzE - - S - - - YqzE-like protein
NFKMLMMI_03445 8.44e-75 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NFKMLMMI_03446 2.45e-28 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NFKMLMMI_03447 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NFKMLMMI_03448 3.1e-91 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
NFKMLMMI_03449 1.5e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NFKMLMMI_03450 5.79e-227 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NFKMLMMI_03451 5.85e-253 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NFKMLMMI_03452 1.34e-231 yqxL - - P - - - Mg2 transporter protein
NFKMLMMI_03453 2.13e-294 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NFKMLMMI_03454 2.41e-175 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NFKMLMMI_03456 2.15e-82 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NFKMLMMI_03457 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NFKMLMMI_03458 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NFKMLMMI_03459 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
NFKMLMMI_03460 2.02e-63 dglA - - S - - - Thiamine-binding protein
NFKMLMMI_03461 1.06e-48 yqgU - - - - - - -
NFKMLMMI_03462 9.93e-162 yqgU - - - - - - -
NFKMLMMI_03463 1.33e-256 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NFKMLMMI_03464 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NFKMLMMI_03465 1.87e-37 yqgQ - - S - - - Protein conserved in bacteria
NFKMLMMI_03466 2.58e-269 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NFKMLMMI_03467 5.38e-11 yqgO - - - - - - -
NFKMLMMI_03468 7.01e-116 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NFKMLMMI_03469 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NFKMLMMI_03470 3.42e-68 yqzD - - - - - - -
NFKMLMMI_03471 1.97e-96 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NFKMLMMI_03472 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NFKMLMMI_03473 2.99e-179 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NFKMLMMI_03474 1.88e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NFKMLMMI_03475 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NFKMLMMI_03476 6.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NFKMLMMI_03477 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NFKMLMMI_03478 5.94e-283 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NFKMLMMI_03479 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NFKMLMMI_03480 7.59e-97 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NFKMLMMI_03481 8.5e-165 yqgB - - S - - - Protein of unknown function (DUF1189)
NFKMLMMI_03482 5.95e-59 yqfZ - - M ko:K06417 - ko00000 LysM domain
NFKMLMMI_03483 1.09e-253 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NFKMLMMI_03484 3.9e-79 yqfX - - S - - - membrane
NFKMLMMI_03485 3.23e-139 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NFKMLMMI_03486 2.63e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NFKMLMMI_03487 2.47e-195 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NFKMLMMI_03488 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
NFKMLMMI_03489 9.16e-209 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NFKMLMMI_03490 3.91e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NFKMLMMI_03491 7.12e-57 yqfQ - - S - - - YqfQ-like protein
NFKMLMMI_03492 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NFKMLMMI_03497 3.54e-282 - - - M - - - domain protein
NFKMLMMI_03498 7.55e-59 orfX1 - - L - - - Transposase
NFKMLMMI_03499 5.6e-173 - - - L - - - Integrase core domain
NFKMLMMI_03502 2e-26 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 COG3505 Type IV secretory pathway, VirD4 components
NFKMLMMI_03504 6.38e-87 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NFKMLMMI_03505 1.88e-299 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
NFKMLMMI_03506 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NFKMLMMI_03507 5.89e-138 - - - L - - - IstB-like ATP binding protein
NFKMLMMI_03509 8.62e-236 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NFKMLMMI_03510 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NFKMLMMI_03511 6.09e-310 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NFKMLMMI_03512 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
NFKMLMMI_03513 5.97e-244 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NFKMLMMI_03514 8.83e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NFKMLMMI_03515 2.36e-166 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NFKMLMMI_03516 2.98e-247 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NFKMLMMI_03517 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NFKMLMMI_03518 1.64e-210 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NFKMLMMI_03519 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NFKMLMMI_03520 2.02e-107 yshB - - S - - - membrane protein, required for colicin V production
NFKMLMMI_03521 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NFKMLMMI_03522 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NFKMLMMI_03523 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
NFKMLMMI_03524 9.33e-150 ywbB - - S - - - Protein of unknown function (DUF2711)
NFKMLMMI_03525 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NFKMLMMI_03526 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_03527 2.18e-172 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NFKMLMMI_03528 5.83e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NFKMLMMI_03529 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NFKMLMMI_03530 2.17e-213 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NFKMLMMI_03531 3.64e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFKMLMMI_03532 3.12e-177 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFKMLMMI_03533 2.58e-183 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NFKMLMMI_03534 1.67e-308 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NFKMLMMI_03535 7.13e-52 ylmC - - S - - - sporulation protein
NFKMLMMI_03536 3.85e-196 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NFKMLMMI_03537 6.55e-155 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NFKMLMMI_03538 8.91e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NFKMLMMI_03539 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NFKMLMMI_03540 3.8e-176 ylmH - - S - - - conserved protein, contains S4-like domain
NFKMLMMI_03541 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NFKMLMMI_03542 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NFKMLMMI_03543 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
NFKMLMMI_03544 8.42e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NFKMLMMI_03545 7.29e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NFKMLMMI_03546 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NFKMLMMI_03547 8.98e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NFKMLMMI_03548 2.06e-204 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NFKMLMMI_03549 1.67e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NFKMLMMI_03550 4.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NFKMLMMI_03551 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NFKMLMMI_03552 6.57e-177 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NFKMLMMI_03553 2.36e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NFKMLMMI_03554 1.17e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NFKMLMMI_03555 1e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NFKMLMMI_03556 7.81e-178 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NFKMLMMI_03557 5.26e-223 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NFKMLMMI_03558 5.92e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NFKMLMMI_03559 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NFKMLMMI_03560 7.4e-179 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NFKMLMMI_03561 1.13e-175 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NFKMLMMI_03562 1.85e-98 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NFKMLMMI_03563 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NFKMLMMI_03564 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NFKMLMMI_03565 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NFKMLMMI_03566 8e-194 yloC - - S - - - stress-induced protein
NFKMLMMI_03567 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NFKMLMMI_03568 1.16e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NFKMLMMI_03569 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NFKMLMMI_03570 1.07e-57 - - - S - - - transposition, DNA-mediated
NFKMLMMI_03571 6.51e-150 - - - S - - - HTH-like domain
NFKMLMMI_03572 4.4e-221 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NFKMLMMI_03573 1.44e-109 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NFKMLMMI_03574 2.69e-158 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NFKMLMMI_03575 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NFKMLMMI_03576 2.83e-239 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NFKMLMMI_03577 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NFKMLMMI_03578 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NFKMLMMI_03579 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NFKMLMMI_03580 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NFKMLMMI_03581 2.61e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NFKMLMMI_03582 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NFKMLMMI_03583 9.24e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NFKMLMMI_03584 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NFKMLMMI_03585 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NFKMLMMI_03586 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NFKMLMMI_03587 1.13e-101 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NFKMLMMI_03588 1.16e-182 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NFKMLMMI_03589 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NFKMLMMI_03590 8.88e-106 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NFKMLMMI_03591 7.21e-200 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NFKMLMMI_03592 3.9e-208 - - - S - - - Fusaric acid resistance protein-like
NFKMLMMI_03593 6.58e-27 - - - - - - - -
NFKMLMMI_03594 0.0 - - - L - - - AAA domain
NFKMLMMI_03595 0.0 - - - L - - - AAA ATPase domain
NFKMLMMI_03596 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NFKMLMMI_03600 5.96e-264 yycP - - - - - - -
NFKMLMMI_03601 1.54e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NFKMLMMI_03602 3.13e-226 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NFKMLMMI_03603 2.13e-106 yycN - - K - - - Acetyltransferase
NFKMLMMI_03605 8.34e-256 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NFKMLMMI_03606 7.27e-210 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NFKMLMMI_03607 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NFKMLMMI_03608 1.75e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NFKMLMMI_03609 1.26e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NFKMLMMI_03610 3.82e-57 sdpR - - K - - - transcriptional
NFKMLMMI_03611 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NFKMLMMI_03612 8.24e-255 - - - S - - - Major Facilitator Superfamily
NFKMLMMI_03613 5.41e-310 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NFKMLMMI_03614 3.35e-119 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
NFKMLMMI_03615 6.88e-86 - - - S - - - Peptidase propeptide and YPEB domain
NFKMLMMI_03616 1.37e-270 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NFKMLMMI_03617 1.53e-81 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NFKMLMMI_03618 2.39e-130 - - - S - - - Domain of unknown function (DUF3885)
NFKMLMMI_03620 1.87e-53 - - - - - - - -
NFKMLMMI_03622 1.09e-117 - - - J - - - Acetyltransferase (GNAT) domain
NFKMLMMI_03623 1.52e-164 yoaP - - K - - - YoaP-like
NFKMLMMI_03624 1.69e-13 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NFKMLMMI_03625 1.95e-39 - - - S - - - Protein of unknown function (DUF4025)
NFKMLMMI_03626 2.04e-10 - - - - - - - -
NFKMLMMI_03627 5.82e-16 - - - - - - - -
NFKMLMMI_03628 1.82e-231 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NFKMLMMI_03629 1.08e-86 dinB - - S - - - DinB family
NFKMLMMI_03631 1.49e-93 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NFKMLMMI_03632 5.72e-314 ygxB - - M - - - Conserved TM helix
NFKMLMMI_03633 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NFKMLMMI_03634 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NFKMLMMI_03635 5.53e-217 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NFKMLMMI_03636 4.96e-148 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NFKMLMMI_03637 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NFKMLMMI_03638 5.54e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NFKMLMMI_03639 0.0 - - - M - - - cell wall anchor domain
NFKMLMMI_03640 0.0 - - - M - - - cell wall anchor domain
NFKMLMMI_03641 4.78e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
NFKMLMMI_03642 0.0 ywpD - - T - - - Histidine kinase
NFKMLMMI_03643 3.08e-92 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
NFKMLMMI_03648 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NFKMLMMI_03649 5.26e-298 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NFKMLMMI_03650 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
NFKMLMMI_03651 2.56e-28 - - - S - - - Protein of unknown function (DUF3212)
NFKMLMMI_03652 1.41e-99 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NFKMLMMI_03653 3.25e-64 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NFKMLMMI_03654 4.02e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NFKMLMMI_03655 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NFKMLMMI_03656 3.06e-249 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NFKMLMMI_03657 8.36e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NFKMLMMI_03658 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NFKMLMMI_03659 4.84e-256 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NFKMLMMI_03660 3.25e-105 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NFKMLMMI_03661 3.5e-49 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NFKMLMMI_03662 4.86e-79 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NFKMLMMI_03663 2.22e-15 - - - - - - - -
NFKMLMMI_03664 5.31e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NFKMLMMI_03665 9.95e-58 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NFKMLMMI_03666 1.68e-74 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NFKMLMMI_03667 3.8e-162 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NFKMLMMI_03668 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NFKMLMMI_03669 4.37e-266 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NFKMLMMI_03670 2.04e-226 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NFKMLMMI_03671 1.89e-191 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NFKMLMMI_03672 4.82e-194 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NFKMLMMI_03673 1.98e-83 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NFKMLMMI_03674 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NFKMLMMI_03675 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NFKMLMMI_03676 2.74e-95 ypmB - - S - - - protein conserved in bacteria
NFKMLMMI_03677 1.57e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NFKMLMMI_03678 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NFKMLMMI_03679 8.05e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NFKMLMMI_03680 1.63e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NFKMLMMI_03681 4.6e-113 ypoC - - - - - - -
NFKMLMMI_03682 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NFKMLMMI_03683 8.49e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NFKMLMMI_03684 1.05e-225 yppC - - S - - - Protein of unknown function (DUF2515)
NFKMLMMI_03689 4.13e-180 spsA - - M - - - Spore Coat
NFKMLMMI_03690 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NFKMLMMI_03691 2.58e-275 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NFKMLMMI_03692 6.34e-195 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NFKMLMMI_03693 2.97e-266 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NFKMLMMI_03694 5.52e-160 spsF - - M ko:K07257 - ko00000 Spore Coat
NFKMLMMI_03695 9.02e-214 spsG - - M - - - Spore Coat
NFKMLMMI_03696 2.9e-170 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NFKMLMMI_03697 5.41e-226 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NFKMLMMI_03698 3.3e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NFKMLMMI_03699 2.6e-109 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NFKMLMMI_03700 4.02e-80 - - - - - - - -
NFKMLMMI_03701 8.64e-312 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NFKMLMMI_03702 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NFKMLMMI_03703 0.0 rocB - - E - - - arginine degradation protein
NFKMLMMI_03704 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NFKMLMMI_03705 9.06e-238 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NFKMLMMI_03706 1.14e-276 ywfA - - EGP - - - -transporter
NFKMLMMI_03707 4.49e-143 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NFKMLMMI_03708 4.67e-174 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NFKMLMMI_03709 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_03710 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NFKMLMMI_03711 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NFKMLMMI_03712 1.6e-290 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NFKMLMMI_03713 2.12e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NFKMLMMI_03715 2.37e-20 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NFKMLMMI_03716 6.64e-185 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NFKMLMMI_03717 2.27e-222 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NFKMLMMI_03718 2.26e-59 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NFKMLMMI_03719 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NFKMLMMI_03720 3.26e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NFKMLMMI_03721 0.0 - - - S - - - Domain of unknown function (DUF4179)
NFKMLMMI_03722 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NFKMLMMI_03723 4.87e-165 yebC - - M - - - Membrane
NFKMLMMI_03725 1.08e-119 yebE - - S - - - UPF0316 protein
NFKMLMMI_03726 1.88e-39 yebG - - S - - - NETI protein
NFKMLMMI_03727 1.87e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NFKMLMMI_03728 1.15e-280 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NFKMLMMI_03729 1.05e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NFKMLMMI_03730 3.8e-163 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NFKMLMMI_03731 2.57e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NFKMLMMI_03732 4.32e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NFKMLMMI_03733 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NFKMLMMI_03734 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NFKMLMMI_03735 2.08e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NFKMLMMI_03736 1.16e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NFKMLMMI_03737 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NFKMLMMI_03738 2.12e-293 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NFKMLMMI_03739 4.48e-81 - - - K - - - helix_turn_helix ASNC type
NFKMLMMI_03740 3.96e-173 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
NFKMLMMI_03741 2.05e-33 - - - S - - - Protein of unknown function (DUF2892)
NFKMLMMI_03742 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NFKMLMMI_03743 2.74e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NFKMLMMI_03744 2.03e-67 yerC - - S - - - protein conserved in bacteria
NFKMLMMI_03745 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NFKMLMMI_03746 5.04e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NFKMLMMI_03750 4e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
NFKMLMMI_03751 4.06e-178 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
NFKMLMMI_03757 5.22e-05 - - - L - - - Protein of unknown function (DUF2800)
NFKMLMMI_03761 5.48e-32 - - - - - - - -
NFKMLMMI_03763 8.45e-82 - - - N - - - bacterial-type flagellum assembly
NFKMLMMI_03767 1.42e-31 - - - - - - - -
NFKMLMMI_03770 3.8e-07 - - - S - - - YopX protein
NFKMLMMI_03771 8.8e-53 - - - - - - - -
NFKMLMMI_03776 8.46e-34 - - - - - - - -
NFKMLMMI_03777 4.66e-239 - - - - - - - -
NFKMLMMI_03784 1.51e-79 - - - - - - - -
NFKMLMMI_03786 4.16e-118 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFKMLMMI_03787 2.83e-121 - - - L - - - HNH endonuclease
NFKMLMMI_03788 3.47e-55 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFKMLMMI_03790 6.38e-16 - - - O - - - Glutaredoxin
NFKMLMMI_03791 3.14e-94 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NFKMLMMI_03796 5.06e-123 - - - S - - - Thymidylate synthase
NFKMLMMI_03797 3.77e-07 - - - S - - - nucleic acid binding
NFKMLMMI_03798 2.42e-61 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NFKMLMMI_03799 2.96e-35 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NFKMLMMI_03802 3.55e-106 - - - - - - - -
NFKMLMMI_03806 6.98e-31 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NFKMLMMI_03807 3.56e-193 - - - S - - - Calcineurin-like phosphoesterase
NFKMLMMI_03814 1.16e-114 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NFKMLMMI_03816 2.43e-48 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NFKMLMMI_03817 5.33e-244 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NFKMLMMI_03818 1.1e-66 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NFKMLMMI_03819 0.0 yhaN - - L - - - AAA domain
NFKMLMMI_03820 3.38e-224 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NFKMLMMI_03821 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
NFKMLMMI_03822 3.2e-182 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NFKMLMMI_03823 4.32e-122 yhaK - - S - - - Putative zincin peptidase
NFKMLMMI_03824 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
NFKMLMMI_03825 1.07e-142 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NFKMLMMI_03826 1.58e-53 yhaH - - S - - - YtxH-like protein
NFKMLMMI_03827 2.55e-24 - - - - - - - -
NFKMLMMI_03828 1.12e-97 trpP - - S - - - Tryptophan transporter TrpP
NFKMLMMI_03829 1.49e-252 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NFKMLMMI_03830 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NFKMLMMI_03831 2.13e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NFKMLMMI_03832 3.4e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NFKMLMMI_03833 1.7e-167 ykwD - - J - - - protein with SCP PR1 domains
NFKMLMMI_03834 9.19e-65 - - - - - - - -
NFKMLMMI_03835 5.71e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NFKMLMMI_03836 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NFKMLMMI_03837 2.29e-252 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NFKMLMMI_03838 1.22e-48 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_03839 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NFKMLMMI_03840 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NFKMLMMI_03841 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_03842 1.54e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NFKMLMMI_03843 4.21e-217 ykvZ - - K - - - Transcriptional regulator
NFKMLMMI_03844 1.51e-259 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NFKMLMMI_03845 4.72e-90 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NFKMLMMI_03846 5.21e-204 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NFKMLMMI_03847 4e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NFKMLMMI_03848 2.69e-265 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NFKMLMMI_03849 3.22e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NFKMLMMI_03850 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
NFKMLMMI_03851 6.26e-170 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NFKMLMMI_03852 6.03e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NFKMLMMI_03853 2.77e-161 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NFKMLMMI_03854 1.79e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NFKMLMMI_03855 3.99e-118 yqjB - - S - - - protein conserved in bacteria
NFKMLMMI_03857 6.09e-92 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NFKMLMMI_03858 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NFKMLMMI_03859 5.04e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NFKMLMMI_03860 6.56e-188 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NFKMLMMI_03861 1.36e-36 yqzJ - - - - - - -
NFKMLMMI_03862 7.78e-294 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NFKMLMMI_03863 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NFKMLMMI_03864 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NFKMLMMI_03865 2.97e-215 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NFKMLMMI_03866 4.44e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NFKMLMMI_03868 2.12e-203 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFKMLMMI_03869 3.25e-48 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFKMLMMI_03870 1.15e-157 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFKMLMMI_03871 1.22e-88 - - - S - - - NrdI Flavodoxin like
NFKMLMMI_03884 1.53e-200 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
NFKMLMMI_03885 1.87e-69 - 2.1.1.113, 2.1.1.72 - L ko:K00571,ko:K00590 - ko00000,ko01000,ko02048 N-4 methylation of cytosine
NFKMLMMI_03886 6.66e-115 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NFKMLMMI_03887 1.68e-89 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
NFKMLMMI_03890 9.77e-30 - - - S - - - protein conserved in bacteria
NFKMLMMI_03891 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NFKMLMMI_03892 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NFKMLMMI_03893 1.15e-261 - - - L - - - DNA primase activity
NFKMLMMI_03894 0.0 - - - J - - - DnaB-like helicase C terminal domain
NFKMLMMI_03895 6.62e-105 - - - - - - - -
NFKMLMMI_03896 5.25e-212 - - - L - - - AAA domain
NFKMLMMI_03897 8.57e-197 - - - - - - - -
NFKMLMMI_03903 1.2e-276 - - - M - - - Parallel beta-helix repeats
NFKMLMMI_03904 2.22e-107 - - - S - - - Pfam:DUF867
NFKMLMMI_03906 1.52e-211 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NFKMLMMI_03907 1.61e-293 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NFKMLMMI_03908 4.01e-44 yvfG - - S - - - YvfG protein
NFKMLMMI_03909 2.77e-224 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NFKMLMMI_03910 2.79e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NFKMLMMI_03911 2.21e-10 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NFKMLMMI_03912 1.67e-59 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NFKMLMMI_03913 4.39e-76 ywdK - - S - - - small membrane protein
NFKMLMMI_03914 3.47e-287 ywdJ - - F - - - Xanthine uracil
NFKMLMMI_03915 2.73e-56 ywdI - - S - - - Family of unknown function (DUF5327)
NFKMLMMI_03916 2.42e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NFKMLMMI_03917 1.44e-186 ywdF - - S - - - Glycosyltransferase like family 2
NFKMLMMI_03919 2.79e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NFKMLMMI_03920 6.09e-27 ywdA - - - - - - -
NFKMLMMI_03921 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NFKMLMMI_03922 4.52e-316 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NFKMLMMI_03923 6.12e-192 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NFKMLMMI_03925 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NFKMLMMI_03926 1.83e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFKMLMMI_03927 1.26e-150 - - - K - - - WYL domain
NFKMLMMI_03928 8.59e-162 ucpA - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_03929 4.61e-56 - - - S - - - Ketosteroid isomerase-related protein
NFKMLMMI_03930 1.36e-39 - - - S - - - PFAM Stress responsive alpha-beta barrel
NFKMLMMI_03931 1.1e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NFKMLMMI_03932 1.84e-262 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NFKMLMMI_03933 1.68e-87 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NFKMLMMI_03934 1.5e-41 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NFKMLMMI_03935 1.08e-80 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NFKMLMMI_03936 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NFKMLMMI_03937 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NFKMLMMI_03938 3.01e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NFKMLMMI_03939 5.74e-48 ydaS - - S - - - membrane
NFKMLMMI_03940 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NFKMLMMI_03941 1.52e-265 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NFKMLMMI_03942 7.8e-78 gtcA - - S - - - GtrA-like protein
NFKMLMMI_03943 1.72e-125 - - - K - - - Bacterial regulatory proteins, tetR family
NFKMLMMI_03945 6.64e-162 - - - H - - - Methionine biosynthesis protein MetW
NFKMLMMI_03946 4.83e-154 - - - S - - - Streptomycin biosynthesis protein StrF
NFKMLMMI_03947 5.52e-139 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NFKMLMMI_03948 1.75e-242 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NFKMLMMI_03949 1.16e-151 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NFKMLMMI_03950 2.07e-264 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFKMLMMI_03951 1.69e-170 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NFKMLMMI_03952 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NFKMLMMI_03953 3.12e-167 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NFKMLMMI_03954 3.08e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NFKMLMMI_03955 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NFKMLMMI_03956 2.88e-190 gntR - - K - - - RpiR family transcriptional regulator
NFKMLMMI_03958 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NFKMLMMI_03959 2.18e-195 yvbV - - EG - - - EamA-like transporter family
NFKMLMMI_03960 2.18e-124 yvbU - - K - - - Transcriptional regulator
NFKMLMMI_03961 3.86e-18 yvbU - - K - - - Transcriptional regulator
NFKMLMMI_03962 1.78e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFKMLMMI_03963 1.76e-257 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NFKMLMMI_03964 4.6e-272 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NFKMLMMI_03966 1.91e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NFKMLMMI_03967 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NFKMLMMI_03968 1.55e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NFKMLMMI_03969 1.49e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NFKMLMMI_03970 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NFKMLMMI_03971 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NFKMLMMI_03972 2.83e-286 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NFKMLMMI_03973 9.36e-317 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NFKMLMMI_03974 2.68e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NFKMLMMI_03975 6.48e-215 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
NFKMLMMI_03976 6.62e-279 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NFKMLMMI_03977 1.44e-178 - - - M - - - Protein involved in cellulose biosynthesis
NFKMLMMI_03978 1.13e-182 - - - C - - - WbqC-like protein family
NFKMLMMI_03979 3.54e-159 - - - S - - - GlcNAc-PI de-N-acetylase
NFKMLMMI_03980 1.87e-219 - - - - - - - -
NFKMLMMI_03981 4.16e-260 - - - EGP - - - Major facilitator Superfamily
NFKMLMMI_03982 1.24e-103 yvbK - - K - - - acetyltransferase
NFKMLMMI_03984 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NFKMLMMI_03985 5.38e-142 yvbI - - M - - - Membrane
NFKMLMMI_03986 7.35e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NFKMLMMI_03987 1.88e-125 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NFKMLMMI_03988 7.33e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NFKMLMMI_03989 3.12e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NFKMLMMI_03990 6.03e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NFKMLMMI_03991 2.08e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NFKMLMMI_03992 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NFKMLMMI_03993 1.39e-259 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NFKMLMMI_03994 2.57e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NFKMLMMI_03995 4.75e-215 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NFKMLMMI_03996 4.05e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NFKMLMMI_03997 1.73e-158 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NFKMLMMI_03998 1.35e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NFKMLMMI_03999 1.93e-167 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NFKMLMMI_04000 7.17e-154 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NFKMLMMI_04001 3.51e-308 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NFKMLMMI_04002 1.17e-67 yvaP - - K - - - transcriptional
NFKMLMMI_04003 1.09e-90 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NFKMLMMI_04004 1.07e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NFKMLMMI_04005 1.64e-47 yvzC - - K - - - transcriptional
NFKMLMMI_04006 9.24e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NFKMLMMI_04007 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NFKMLMMI_04008 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NFKMLMMI_04009 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NFKMLMMI_04011 9.41e-56 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NFKMLMMI_04012 1.18e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NFKMLMMI_04013 4.27e-201 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
NFKMLMMI_04014 2.26e-21 yqaO - - S - - - Phage-like element PBSX protein XtrA
NFKMLMMI_04017 4.2e-36 - - - - - - - -
NFKMLMMI_04018 2.96e-08 - - - - - - - -
NFKMLMMI_04020 2.62e-40 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NFKMLMMI_04021 3.44e-116 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
NFKMLMMI_04023 6.41e-50 - - - S - - - Domain of unknown function (DUF771)
NFKMLMMI_04024 4.18e-07 ahdIC - - K - - - PFAM helix-turn-helix domain protein
NFKMLMMI_04025 6.42e-48 - - - K - - - Helix-turn-helix XRE-family like proteins
NFKMLMMI_04028 1.4e-90 - - - - - - - -
NFKMLMMI_04029 5.85e-167 - - - L - - - Phage integrase family
NFKMLMMI_04045 2.42e-61 - - - S - - - GlpM protein
NFKMLMMI_04046 9.08e-202 - - - K - - - LysR substrate binding domain
NFKMLMMI_04047 3.26e-33 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NFKMLMMI_04049 1e-254 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NFKMLMMI_04050 1.88e-224 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NFKMLMMI_04051 7.59e-180 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NFKMLMMI_04052 2.56e-307 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NFKMLMMI_04053 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NFKMLMMI_04054 9.6e-47 ydjO - - S - - - Cold-inducible protein YdjO
NFKMLMMI_04056 1.51e-189 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NFKMLMMI_04057 7.91e-83 ydjM - - M - - - Lytic transglycolase
NFKMLMMI_04058 6.49e-245 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NFKMLMMI_04059 1.08e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NFKMLMMI_04060 5.52e-184 rsiV - - S - - - Protein of unknown function (DUF3298)
NFKMLMMI_04061 0.0 oatA - - I - - - Acyltransferase family
NFKMLMMI_04062 4.64e-200 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NFKMLMMI_04063 3.97e-156 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NFKMLMMI_04064 6.45e-222 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NFKMLMMI_04065 4.36e-143 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NFKMLMMI_04066 1.47e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
NFKMLMMI_04067 4.48e-211 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NFKMLMMI_04068 9.02e-311 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NFKMLMMI_04069 9.34e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NFKMLMMI_04070 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NFKMLMMI_04071 2.21e-81 - - - - - - - -
NFKMLMMI_04073 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
NFKMLMMI_04074 2.3e-276 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NFKMLMMI_04075 2.3e-91 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NFKMLMMI_04076 2.66e-305 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NFKMLMMI_04077 4.04e-136 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NFKMLMMI_04078 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NFKMLMMI_04079 2.03e-249 yhdL - - S - - - Sigma factor regulator N-terminal
NFKMLMMI_04080 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
NFKMLMMI_04081 4.63e-264 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NFKMLMMI_04082 1.1e-311 yhdG - - E ko:K03294 - ko00000 amino acid
NFKMLMMI_04083 3.42e-200 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFKMLMMI_04084 2.19e-250 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NFKMLMMI_04085 1.7e-201 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NFKMLMMI_04086 7.24e-38 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NFKMLMMI_04087 2.03e-64 - - - - - - - -
NFKMLMMI_04088 2.31e-90 - - - S - - - Bacterial EndoU nuclease
NFKMLMMI_04089 1.06e-42 - - - - - - - -
NFKMLMMI_04090 1.86e-116 yokH - - G - - - SMI1 / KNR4 family
NFKMLMMI_04091 1.61e-128 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 2-dehydropantoate 2-reductase
NFKMLMMI_04092 2.21e-28 yokK - - S - - - SMI1 / KNR4 family
NFKMLMMI_04093 9.5e-81 - - - H - - - Acetyltransferase (GNAT) domain
NFKMLMMI_04095 1.44e-132 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NFKMLMMI_04096 3.28e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NFKMLMMI_04097 4.16e-17 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NFKMLMMI_04098 4.99e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NFKMLMMI_04099 1.98e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NFKMLMMI_04100 4.08e-306 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NFKMLMMI_04101 6.52e-237 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NFKMLMMI_04102 3.17e-234 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NFKMLMMI_04103 3.61e-34 - - - - - - - -
NFKMLMMI_04104 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NFKMLMMI_04105 2.79e-293 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NFKMLMMI_04106 1.4e-159 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NFKMLMMI_04107 4.15e-191 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NFKMLMMI_04108 1.6e-128 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NFKMLMMI_04109 1.19e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NFKMLMMI_04110 2.91e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NFKMLMMI_04111 4.16e-200 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NFKMLMMI_04112 3.98e-107 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NFKMLMMI_04113 1.61e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NFKMLMMI_04114 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NFKMLMMI_04115 2.65e-177 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NFKMLMMI_04116 3.7e-199 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NFKMLMMI_04117 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NFKMLMMI_04118 5.78e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NFKMLMMI_04119 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NFKMLMMI_04120 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NFKMLMMI_04121 5.59e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NFKMLMMI_04122 1.4e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NFKMLMMI_04123 1.15e-140 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NFKMLMMI_04125 8.22e-19 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NFKMLMMI_04132 0.0 yclG - - M - - - Pectate lyase superfamily protein
NFKMLMMI_04133 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NFKMLMMI_04134 8.93e-96 yclD - - - - - - -
NFKMLMMI_04135 6.46e-49 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
NFKMLMMI_04136 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NFKMLMMI_04137 6.94e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NFKMLMMI_04138 2.91e-197 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NFKMLMMI_04139 2.34e-179 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NFKMLMMI_04140 5.85e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NFKMLMMI_04141 1.32e-167 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NFKMLMMI_04142 1.12e-137 yczE - - S ko:K07149 - ko00000 membrane
NFKMLMMI_04143 5.87e-155 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NFKMLMMI_04144 2.92e-314 - - - E - - - Aminotransferase class I and II
NFKMLMMI_04145 1.14e-175 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NFKMLMMI_04146 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NFKMLMMI_04147 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFKMLMMI_04148 1.65e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NFKMLMMI_04149 8e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NFKMLMMI_04150 1.11e-288 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NFKMLMMI_04151 4.54e-111 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NFKMLMMI_04152 1.4e-62 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NFKMLMMI_04162 2.09e-266 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NFKMLMMI_04163 1.79e-157 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NFKMLMMI_04164 6.7e-119 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NFKMLMMI_04165 5.54e-40 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NFKMLMMI_04166 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
NFKMLMMI_04167 5.69e-26 yflI - - - - - - -
NFKMLMMI_04168 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
NFKMLMMI_04169 1.9e-153 yflK - - S - - - protein conserved in bacteria
NFKMLMMI_04170 4.43e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NFKMLMMI_04171 7.02e-269 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NFKMLMMI_04172 3.39e-183 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NFKMLMMI_04173 9.38e-165 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NFKMLMMI_04174 1.4e-103 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NFKMLMMI_04175 2.12e-185 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NFKMLMMI_04176 3.69e-165 yfmS - - NT - - - chemotaxis protein
NFKMLMMI_04177 6.04e-60 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NFKMLMMI_04178 8.83e-100 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NFKMLMMI_04180 4.37e-132 yfnE - - S - - - Glycosyltransferase like family 2
NFKMLMMI_04181 5.43e-227 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NFKMLMMI_04182 7.72e-210 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NFKMLMMI_04183 2.98e-55 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NFKMLMMI_04184 2.22e-114 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NFKMLMMI_04185 8.78e-133 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NFKMLMMI_04186 1.94e-44 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NFKMLMMI_04187 8.6e-117 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFKMLMMI_04188 9.54e-43 ymaB - - S - - - MutT family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)