ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PLHLKKDO_00007 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PLHLKKDO_00008 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PLHLKKDO_00009 6.43e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
PLHLKKDO_00010 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
PLHLKKDO_00011 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PLHLKKDO_00012 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
PLHLKKDO_00013 1.06e-259 cotI - - S ko:K06331 - ko00000 Spore coat protein
PLHLKKDO_00014 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
PLHLKKDO_00015 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
PLHLKKDO_00017 5.88e-297 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
PLHLKKDO_00018 1.23e-227 ytcB - - M - - - NAD-dependent epimerase dehydratase
PLHLKKDO_00019 9.26e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PLHLKKDO_00020 2.32e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
PLHLKKDO_00021 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
PLHLKKDO_00022 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PLHLKKDO_00023 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PLHLKKDO_00024 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PLHLKKDO_00025 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PLHLKKDO_00026 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PLHLKKDO_00027 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PLHLKKDO_00028 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PLHLKKDO_00029 6.12e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PLHLKKDO_00030 5.24e-296 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PLHLKKDO_00031 2.65e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
PLHLKKDO_00032 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
PLHLKKDO_00033 6.96e-240 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PLHLKKDO_00034 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PLHLKKDO_00035 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
PLHLKKDO_00036 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PLHLKKDO_00037 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PLHLKKDO_00038 4.78e-95 ytkA - - S - - - YtkA-like
PLHLKKDO_00040 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PLHLKKDO_00041 3.2e-81 ytkC - - S - - - Bacteriophage holin family
PLHLKKDO_00042 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PLHLKKDO_00043 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PLHLKKDO_00044 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PLHLKKDO_00045 2.66e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PLHLKKDO_00046 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PLHLKKDO_00047 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
PLHLKKDO_00048 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PLHLKKDO_00049 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PLHLKKDO_00050 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PLHLKKDO_00051 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PLHLKKDO_00052 1.68e-87 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PLHLKKDO_00053 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
PLHLKKDO_00054 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
PLHLKKDO_00055 1.86e-134 ytqB - - J - - - Putative rRNA methylase
PLHLKKDO_00056 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
PLHLKKDO_00057 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
PLHLKKDO_00059 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
PLHLKKDO_00060 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_00061 5.07e-201 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PLHLKKDO_00062 1.3e-190 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
PLHLKKDO_00063 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_00064 5.92e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PLHLKKDO_00065 1.46e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_00066 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
PLHLKKDO_00067 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_00068 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
PLHLKKDO_00069 6.61e-77 yttA - - S - - - Pfam Transposase IS66
PLHLKKDO_00070 9.96e-268 yttB - - EGP - - - Major facilitator superfamily
PLHLKKDO_00071 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PLHLKKDO_00072 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
PLHLKKDO_00073 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PLHLKKDO_00074 7.08e-68 ytwF - - P - - - Sulfurtransferase
PLHLKKDO_00075 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
PLHLKKDO_00076 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PLHLKKDO_00077 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PLHLKKDO_00078 2.12e-311 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PLHLKKDO_00079 2.17e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_00080 1.13e-219 - - - S - - - Acetyl xylan esterase (AXE1)
PLHLKKDO_00081 3.06e-190 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PLHLKKDO_00082 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PLHLKKDO_00083 1.05e-274 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PLHLKKDO_00084 1.09e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PLHLKKDO_00085 1.53e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PLHLKKDO_00086 3.75e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PLHLKKDO_00087 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
PLHLKKDO_00088 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PLHLKKDO_00089 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
PLHLKKDO_00090 0.0 ytdP - - K - - - Transcriptional regulator
PLHLKKDO_00091 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
PLHLKKDO_00092 3.95e-277 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
PLHLKKDO_00093 4.78e-94 yteS - - G - - - transport
PLHLKKDO_00094 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
PLHLKKDO_00095 8.98e-149 yteU - - S - - - Integral membrane protein
PLHLKKDO_00096 2.14e-36 yteV - - S - - - Sporulation protein Cse60
PLHLKKDO_00097 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
PLHLKKDO_00098 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
PLHLKKDO_00099 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PLHLKKDO_00100 3.03e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PLHLKKDO_00101 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
PLHLKKDO_00102 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PLHLKKDO_00103 1.94e-252 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
PLHLKKDO_00104 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
PLHLKKDO_00105 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
PLHLKKDO_00106 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PLHLKKDO_00107 1.28e-131 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PLHLKKDO_00108 4.92e-212 ytlQ - - - - - - -
PLHLKKDO_00109 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
PLHLKKDO_00110 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
PLHLKKDO_00111 1.75e-191 ytmP - - M - - - Phosphotransferase
PLHLKKDO_00112 9.51e-61 ytzH - - S - - - YtzH-like protein
PLHLKKDO_00113 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PLHLKKDO_00114 1.06e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PLHLKKDO_00115 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PLHLKKDO_00116 4.06e-68 ytzB - - S - - - small secreted protein
PLHLKKDO_00117 9.11e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
PLHLKKDO_00118 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
PLHLKKDO_00119 3.17e-75 ytpP - - CO - - - Thioredoxin
PLHLKKDO_00120 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
PLHLKKDO_00121 7.25e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PLHLKKDO_00122 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PLHLKKDO_00123 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PLHLKKDO_00124 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PLHLKKDO_00125 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
PLHLKKDO_00126 3.17e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
PLHLKKDO_00127 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PLHLKKDO_00128 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
PLHLKKDO_00129 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PLHLKKDO_00130 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PLHLKKDO_00131 2.69e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
PLHLKKDO_00132 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
PLHLKKDO_00133 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PLHLKKDO_00134 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PLHLKKDO_00135 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PLHLKKDO_00137 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PLHLKKDO_00138 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
PLHLKKDO_00139 1.13e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
PLHLKKDO_00140 1.2e-141 yttP - - K - - - Transcriptional regulator
PLHLKKDO_00141 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PLHLKKDO_00142 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PLHLKKDO_00143 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PLHLKKDO_00144 5.54e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PLHLKKDO_00145 1.04e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PLHLKKDO_00146 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
PLHLKKDO_00147 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PLHLKKDO_00148 0.0 ytcJ - - S - - - amidohydrolase
PLHLKKDO_00149 9.78e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PLHLKKDO_00150 9.73e-230 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
PLHLKKDO_00151 4.08e-112 yteJ - - S - - - RDD family
PLHLKKDO_00152 1.68e-148 ytfI - - S - - - Protein of unknown function (DUF2953)
PLHLKKDO_00153 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
PLHLKKDO_00154 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PLHLKKDO_00155 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
PLHLKKDO_00156 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PLHLKKDO_00157 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
PLHLKKDO_00158 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
PLHLKKDO_00159 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
PLHLKKDO_00161 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_00162 2.71e-166 ytkL - - S - - - Belongs to the UPF0173 family
PLHLKKDO_00163 7.94e-220 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
PLHLKKDO_00164 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PLHLKKDO_00165 9.11e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PLHLKKDO_00166 8.91e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PLHLKKDO_00167 9.59e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PLHLKKDO_00168 4.57e-153 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PLHLKKDO_00169 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PLHLKKDO_00170 8.05e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLHLKKDO_00171 5.07e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
PLHLKKDO_00172 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLHLKKDO_00173 9.41e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
PLHLKKDO_00174 9.12e-301 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
PLHLKKDO_00175 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
PLHLKKDO_00176 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
PLHLKKDO_00177 2.15e-63 ytpI - - S - - - YtpI-like protein
PLHLKKDO_00178 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
PLHLKKDO_00179 1.15e-39 - - - - - - - -
PLHLKKDO_00180 2.08e-111 ytrI - - - - - - -
PLHLKKDO_00181 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
PLHLKKDO_00182 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PLHLKKDO_00183 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PLHLKKDO_00184 1.25e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PLHLKKDO_00185 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PLHLKKDO_00186 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PLHLKKDO_00187 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
PLHLKKDO_00188 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
PLHLKKDO_00189 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
PLHLKKDO_00190 1.56e-93 ytwI - - S - - - membrane
PLHLKKDO_00191 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PLHLKKDO_00192 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
PLHLKKDO_00193 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
PLHLKKDO_00194 4.64e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_00195 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
PLHLKKDO_00196 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PLHLKKDO_00197 3.88e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PLHLKKDO_00198 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
PLHLKKDO_00199 3.29e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PLHLKKDO_00200 4.54e-205 ytbE - - S - - - reductase
PLHLKKDO_00201 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
PLHLKKDO_00202 9.85e-88 ytcD - - K - - - Transcriptional regulator
PLHLKKDO_00203 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PLHLKKDO_00204 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PLHLKKDO_00205 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PLHLKKDO_00206 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
PLHLKKDO_00207 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
PLHLKKDO_00208 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
PLHLKKDO_00209 2e-204 ytxC - - S - - - YtxC-like family
PLHLKKDO_00211 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PLHLKKDO_00212 1.4e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
PLHLKKDO_00213 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_00214 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
PLHLKKDO_00215 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PLHLKKDO_00216 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PLHLKKDO_00218 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PLHLKKDO_00219 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
PLHLKKDO_00220 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PLHLKKDO_00221 1.27e-59 ysdA - - S - - - Membrane
PLHLKKDO_00222 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
PLHLKKDO_00223 8.77e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
PLHLKKDO_00224 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PLHLKKDO_00225 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
PLHLKKDO_00226 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
PLHLKKDO_00227 1.99e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PLHLKKDO_00228 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
PLHLKKDO_00229 1.07e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PLHLKKDO_00230 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
PLHLKKDO_00231 1.12e-217 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
PLHLKKDO_00232 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
PLHLKKDO_00233 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
PLHLKKDO_00234 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
PLHLKKDO_00235 8.8e-55 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
PLHLKKDO_00236 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
PLHLKKDO_00237 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
PLHLKKDO_00238 2.51e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
PLHLKKDO_00239 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
PLHLKKDO_00240 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PLHLKKDO_00241 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PLHLKKDO_00242 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PLHLKKDO_00243 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PLHLKKDO_00244 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PLHLKKDO_00245 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
PLHLKKDO_00246 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
PLHLKKDO_00247 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PLHLKKDO_00248 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
PLHLKKDO_00249 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PLHLKKDO_00250 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_00251 3.12e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
PLHLKKDO_00252 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
PLHLKKDO_00253 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
PLHLKKDO_00255 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
PLHLKKDO_00256 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PLHLKKDO_00257 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PLHLKKDO_00258 6.56e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PLHLKKDO_00259 3.48e-103 yslB - - S - - - Protein of unknown function (DUF2507)
PLHLKKDO_00260 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
PLHLKKDO_00261 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PLHLKKDO_00262 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PLHLKKDO_00263 6.51e-103 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
PLHLKKDO_00264 6.14e-25 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_00265 4.75e-63 xkdA - - E - - - IrrE N-terminal-like domain
PLHLKKDO_00266 2.71e-20 - - - - - - - -
PLHLKKDO_00268 1.79e-30 - - - K ko:K07467 - ko00000 sequence-specific DNA binding
PLHLKKDO_00269 1.49e-20 - - - K - - - Helix-turn-helix XRE-family like proteins
PLHLKKDO_00271 3.74e-63 - - - S - - - DNA binding
PLHLKKDO_00272 2.69e-88 - - - - - - - -
PLHLKKDO_00277 7.67e-193 yqaJ - - L - - - YqaJ-like viral recombinase domain
PLHLKKDO_00278 3.08e-149 recT - - L ko:K07455 - ko00000,ko03400 RecT family
PLHLKKDO_00279 6.15e-172 yqaM - - L - - - IstB-like ATP binding protein
PLHLKKDO_00281 1.97e-20 - - - S - - - YopX protein
PLHLKKDO_00282 9.06e-71 - - - S - - - Protein of unknown function (DUF1064)
PLHLKKDO_00284 2.52e-18 - - - L - - - HNH endonuclease
PLHLKKDO_00285 6.2e-35 yqaO - - S - - - Phage-like element PBSX protein XtrA
PLHLKKDO_00295 3.72e-91 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PLHLKKDO_00297 5.1e-24 - - - K - - - Transcriptional regulator
PLHLKKDO_00299 5.29e-115 yqaS - - L - - - DNA packaging
PLHLKKDO_00300 6.59e-236 - - - S - - - Terminase-like family
PLHLKKDO_00301 2.1e-195 - - - S - - - Phage portal protein, SPP1 Gp6-like
PLHLKKDO_00303 7.35e-80 - - - S - - - Domain of unknown function (DUF4355)
PLHLKKDO_00304 5.04e-141 - - - S - - - Phage capsid family
PLHLKKDO_00306 2.67e-40 - - - S - - - Phage Mu protein F like protein
PLHLKKDO_00308 2.31e-59 - - - - - - - -
PLHLKKDO_00310 8.93e-42 - - - - - - - -
PLHLKKDO_00311 7.99e-129 - - - S - - - Protein of unknown function (DUF3383)
PLHLKKDO_00312 1.84e-45 - - - - - - - -
PLHLKKDO_00313 7.49e-22 - - - - - - - -
PLHLKKDO_00314 4.9e-164 - - - N - - - phage tail tape measure protein
PLHLKKDO_00315 6.22e-47 - - - M - - - LysM domain
PLHLKKDO_00316 1.86e-40 - - - - - - - -
PLHLKKDO_00317 2.6e-111 - - - - - - - -
PLHLKKDO_00319 2.25e-30 - - - S - - - Protein of unknown function (DUF2634)
PLHLKKDO_00320 3.45e-133 - - - S - - - homolog of phage Mu protein gp47
PLHLKKDO_00321 8.61e-79 - - - - - - - -
PLHLKKDO_00322 1.91e-51 - - - - - - - -
PLHLKKDO_00324 2.03e-17 xkdX - - - - - - -
PLHLKKDO_00325 1.95e-37 xhlA - - S - - - Haemolysin XhlA
PLHLKKDO_00326 1.58e-41 xhlB - - S - - - SPP1 phage holin
PLHLKKDO_00327 1.79e-134 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PLHLKKDO_00328 4.47e-47 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
PLHLKKDO_00329 4.63e-57 - - - S - - - YolD-like protein
PLHLKKDO_00330 7.52e-206 - - - L - - - Recombinase
PLHLKKDO_00331 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
PLHLKKDO_00332 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PLHLKKDO_00333 1.62e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
PLHLKKDO_00334 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PLHLKKDO_00335 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PLHLKKDO_00336 1.16e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
PLHLKKDO_00338 1.01e-184 ysnF - - S - - - protein conserved in bacteria
PLHLKKDO_00339 4.03e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
PLHLKKDO_00340 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PLHLKKDO_00341 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PLHLKKDO_00342 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PLHLKKDO_00343 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PLHLKKDO_00344 1.23e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PLHLKKDO_00345 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PLHLKKDO_00346 1.26e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PLHLKKDO_00347 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
PLHLKKDO_00348 5.13e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PLHLKKDO_00349 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PLHLKKDO_00350 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
PLHLKKDO_00351 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PLHLKKDO_00352 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
PLHLKKDO_00353 6.77e-116 ysxD - - - - - - -
PLHLKKDO_00354 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PLHLKKDO_00355 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
PLHLKKDO_00356 8.91e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PLHLKKDO_00357 1.44e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PLHLKKDO_00358 1.51e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
PLHLKKDO_00359 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PLHLKKDO_00360 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
PLHLKKDO_00361 1.49e-248 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PLHLKKDO_00362 1.53e-35 - - - - - - - -
PLHLKKDO_00363 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PLHLKKDO_00364 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PLHLKKDO_00365 9e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PLHLKKDO_00366 7.89e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
PLHLKKDO_00367 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
PLHLKKDO_00368 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
PLHLKKDO_00369 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
PLHLKKDO_00370 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
PLHLKKDO_00371 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
PLHLKKDO_00372 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PLHLKKDO_00373 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
PLHLKKDO_00374 1.06e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PLHLKKDO_00375 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
PLHLKKDO_00376 1.82e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PLHLKKDO_00377 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
PLHLKKDO_00378 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
PLHLKKDO_00379 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
PLHLKKDO_00380 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PLHLKKDO_00381 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
PLHLKKDO_00382 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
PLHLKKDO_00383 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
PLHLKKDO_00384 2.43e-283 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PLHLKKDO_00385 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
PLHLKKDO_00386 4.34e-203 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
PLHLKKDO_00387 6.53e-272 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PLHLKKDO_00388 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
PLHLKKDO_00389 1.47e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PLHLKKDO_00390 1.43e-163 yebC - - K - - - transcriptional regulatory protein
PLHLKKDO_00391 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
PLHLKKDO_00392 3.62e-67 - - - S - - - Family of unknown function (DUF5412)
PLHLKKDO_00394 2.32e-152 yrzF - - T - - - serine threonine protein kinase
PLHLKKDO_00395 6.51e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
PLHLKKDO_00396 0.0 csbX - - EGP - - - the major facilitator superfamily
PLHLKKDO_00397 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
PLHLKKDO_00398 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PLHLKKDO_00399 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PLHLKKDO_00400 1.68e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
PLHLKKDO_00401 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PLHLKKDO_00402 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PLHLKKDO_00403 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
PLHLKKDO_00404 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
PLHLKKDO_00405 2.58e-146 yrbG - - S - - - membrane
PLHLKKDO_00406 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PLHLKKDO_00407 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
PLHLKKDO_00408 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PLHLKKDO_00409 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PLHLKKDO_00410 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
PLHLKKDO_00411 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PLHLKKDO_00412 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PLHLKKDO_00413 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PLHLKKDO_00414 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PLHLKKDO_00415 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
PLHLKKDO_00417 1.49e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
PLHLKKDO_00418 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PLHLKKDO_00419 5.63e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PLHLKKDO_00420 2.44e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PLHLKKDO_00421 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_00422 1.8e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PLHLKKDO_00423 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PLHLKKDO_00424 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
PLHLKKDO_00425 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PLHLKKDO_00426 5.87e-107 yrrD - - S - - - protein conserved in bacteria
PLHLKKDO_00427 8.4e-42 yrzR - - - - - - -
PLHLKKDO_00428 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
PLHLKKDO_00429 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PLHLKKDO_00430 1.32e-138 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PLHLKKDO_00431 5.2e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PLHLKKDO_00432 1.55e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PLHLKKDO_00433 8.81e-242 yrrI - - S - - - AI-2E family transporter
PLHLKKDO_00434 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PLHLKKDO_00435 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
PLHLKKDO_00436 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PLHLKKDO_00437 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
PLHLKKDO_00438 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PLHLKKDO_00439 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
PLHLKKDO_00440 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
PLHLKKDO_00441 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
PLHLKKDO_00442 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
PLHLKKDO_00443 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PLHLKKDO_00444 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
PLHLKKDO_00445 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
PLHLKKDO_00446 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
PLHLKKDO_00447 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
PLHLKKDO_00448 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PLHLKKDO_00449 4.07e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
PLHLKKDO_00450 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PLHLKKDO_00451 6.93e-49 yrhC - - S - - - YrhC-like protein
PLHLKKDO_00452 7.06e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
PLHLKKDO_00453 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
PLHLKKDO_00454 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
PLHLKKDO_00456 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
PLHLKKDO_00458 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
PLHLKKDO_00459 1.1e-126 yrhH - - Q - - - methyltransferase
PLHLKKDO_00460 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
PLHLKKDO_00461 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PLHLKKDO_00462 7.65e-62 yrhK - - S - - - YrhK-like protein
PLHLKKDO_00463 0.0 oatA - - I - - - Acyltransferase family
PLHLKKDO_00464 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
PLHLKKDO_00465 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_00466 1.98e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
PLHLKKDO_00467 1.61e-136 yrhP - - E - - - LysE type translocator
PLHLKKDO_00468 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PLHLKKDO_00469 0.0 levR - - K - - - PTS system fructose IIA component
PLHLKKDO_00470 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
PLHLKKDO_00471 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
PLHLKKDO_00472 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
PLHLKKDO_00473 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
PLHLKKDO_00474 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PLHLKKDO_00475 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PLHLKKDO_00476 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
PLHLKKDO_00477 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
PLHLKKDO_00478 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
PLHLKKDO_00479 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
PLHLKKDO_00480 6.11e-36 yraE - - - ko:K06440 - ko00000 -
PLHLKKDO_00481 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PLHLKKDO_00482 9.61e-84 yraF - - M - - - Spore coat protein
PLHLKKDO_00483 1.2e-49 yraG - - - ko:K06440 - ko00000 -
PLHLKKDO_00484 5.45e-86 - - - E - - - Glyoxalase-like domain
PLHLKKDO_00486 2.92e-81 - - - T - - - sh3 domain protein
PLHLKKDO_00487 6.61e-80 - - - T - - - sh3 domain protein
PLHLKKDO_00488 3.41e-191 - - - S - - - Alpha beta hydrolase
PLHLKKDO_00489 6.94e-54 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PLHLKKDO_00490 3.65e-192 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PLHLKKDO_00491 1.15e-260 yraM - - S - - - PrpF protein
PLHLKKDO_00492 7e-209 yraN - - K - - - Transcriptional regulator
PLHLKKDO_00493 1.77e-284 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PLHLKKDO_00494 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
PLHLKKDO_00495 1.39e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_00496 1.04e-166 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
PLHLKKDO_00497 4.65e-63 - - - S - - - YjbR
PLHLKKDO_00498 1.12e-156 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
PLHLKKDO_00499 3.1e-126 - - - S - - - Flavin reductase like domain
PLHLKKDO_00500 4.98e-172 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
PLHLKKDO_00501 8.71e-194 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
PLHLKKDO_00502 6.21e-148 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_00503 1.67e-267 - - - P - - - Major Facilitator Superfamily
PLHLKKDO_00505 1.16e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
PLHLKKDO_00506 5.63e-161 yrpD - - S - - - Domain of unknown function, YrpD
PLHLKKDO_00507 1.02e-189 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PLHLKKDO_00509 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PLHLKKDO_00510 8.2e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
PLHLKKDO_00511 1.42e-118 yrdA - - S - - - DinB family
PLHLKKDO_00512 1.42e-69 - - - S - - - Protein of unknown function (DUF2568)
PLHLKKDO_00513 7.38e-131 yrdC - - Q - - - Isochorismatase family
PLHLKKDO_00515 1.88e-290 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PLHLKKDO_00516 1.76e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
PLHLKKDO_00517 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
PLHLKKDO_00518 9.34e-176 azlC - - E - - - AzlC protein
PLHLKKDO_00519 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
PLHLKKDO_00520 2.47e-292 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PLHLKKDO_00521 2.43e-208 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
PLHLKKDO_00522 3.53e-87 yodA - - S - - - tautomerase
PLHLKKDO_00523 9.32e-201 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
PLHLKKDO_00524 5.22e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
PLHLKKDO_00525 9.47e-202 - - - K - - - Transcriptional regulator
PLHLKKDO_00526 1.41e-215 yrdR - - EG - - - EamA-like transporter family
PLHLKKDO_00527 2.45e-23 - - - S - - - YrzO-like protein
PLHLKKDO_00528 2.8e-295 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PLHLKKDO_00529 1.46e-106 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
PLHLKKDO_00530 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_00531 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
PLHLKKDO_00532 5.21e-137 yrkC - - G - - - Cupin domain
PLHLKKDO_00533 4.38e-52 yrkD - - S - - - protein conserved in bacteria
PLHLKKDO_00534 1.61e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
PLHLKKDO_00535 9.3e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
PLHLKKDO_00536 2.16e-265 yrkH - - P - - - Rhodanese Homology Domain
PLHLKKDO_00537 2.63e-48 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
PLHLKKDO_00538 3.14e-160 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
PLHLKKDO_00539 5.13e-207 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
PLHLKKDO_00540 1.57e-274 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
PLHLKKDO_00541 1.94e-145 tetR3 - - K ko:K18476 - ko00000,ko00002,ko03000 Transcriptional regulator
PLHLKKDO_00542 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLHLKKDO_00543 2.62e-121 xkdA - - E - - - IrrE N-terminal-like domain
PLHLKKDO_00544 4.16e-130 yqaC - - F - - - adenylate kinase activity
PLHLKKDO_00545 2.52e-119 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
PLHLKKDO_00546 3e-54 - - - - - - - -
PLHLKKDO_00547 2.91e-283 - - - - - - - -
PLHLKKDO_00548 1.01e-73 xkdW - - S - - - XkdW protein
PLHLKKDO_00549 9.34e-33 - - - - - - - -
PLHLKKDO_00550 2.45e-213 xepA - - - - - - -
PLHLKKDO_00551 8.36e-89 - - - S - - - Bacteriophage holin family
PLHLKKDO_00552 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PLHLKKDO_00554 5.4e-80 - - - - - - - -
PLHLKKDO_00556 1.37e-135 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
PLHLKKDO_00557 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
PLHLKKDO_00560 1.14e-117 - - - S - - - Tetratricopeptide repeat
PLHLKKDO_00561 4.35e-53 - - - S - - - Spore coat protein Z
PLHLKKDO_00562 1.51e-54 - - - S - - - Protein of unknown function (DUF3992)
PLHLKKDO_00563 3.73e-62 - - - - - - - -
PLHLKKDO_00564 1.78e-175 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
PLHLKKDO_00565 3.16e-81 - - - K - - - BetI-type transcriptional repressor, C-terminal
PLHLKKDO_00566 1.69e-142 - - - S - - - PepSY-associated TM region
PLHLKKDO_00567 9e-62 - - - S - - - PepSY-associated TM region
PLHLKKDO_00568 1.37e-30 - - - S - - - YtkA-like
PLHLKKDO_00569 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
PLHLKKDO_00570 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
PLHLKKDO_00571 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PLHLKKDO_00572 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
PLHLKKDO_00573 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
PLHLKKDO_00574 0.0 - - - L ko:K06400 - ko00000 Recombinase
PLHLKKDO_00575 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLHLKKDO_00576 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
PLHLKKDO_00577 9.03e-123 - - - - - - - -
PLHLKKDO_00578 1.26e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
PLHLKKDO_00579 1.89e-134 yqeD - - S - - - SNARE associated Golgi protein
PLHLKKDO_00580 1.33e-173 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PLHLKKDO_00581 2.15e-180 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
PLHLKKDO_00583 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
PLHLKKDO_00584 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PLHLKKDO_00585 6.94e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PLHLKKDO_00586 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
PLHLKKDO_00587 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PLHLKKDO_00588 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
PLHLKKDO_00589 1.39e-81 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PLHLKKDO_00590 1.39e-178 yqeM - - Q - - - Methyltransferase
PLHLKKDO_00591 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PLHLKKDO_00592 3.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
PLHLKKDO_00593 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
PLHLKKDO_00594 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PLHLKKDO_00595 2.36e-22 - - - S - - - YqzM-like protein
PLHLKKDO_00596 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PLHLKKDO_00597 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
PLHLKKDO_00598 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PLHLKKDO_00599 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
PLHLKKDO_00600 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
PLHLKKDO_00601 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PLHLKKDO_00602 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
PLHLKKDO_00603 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PLHLKKDO_00604 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PLHLKKDO_00605 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PLHLKKDO_00606 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PLHLKKDO_00607 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
PLHLKKDO_00608 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PLHLKKDO_00609 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
PLHLKKDO_00610 1.4e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
PLHLKKDO_00611 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
PLHLKKDO_00612 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
PLHLKKDO_00613 5.37e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
PLHLKKDO_00614 4.35e-192 yqfA - - S - - - UPF0365 protein
PLHLKKDO_00615 6.04e-61 yqfB - - - - - - -
PLHLKKDO_00616 2.07e-60 yqfC - - S - - - sporulation protein YqfC
PLHLKKDO_00617 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
PLHLKKDO_00618 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
PLHLKKDO_00620 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
PLHLKKDO_00621 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PLHLKKDO_00622 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
PLHLKKDO_00623 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PLHLKKDO_00624 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PLHLKKDO_00625 5.29e-27 - - - S - - - YqzL-like protein
PLHLKKDO_00626 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PLHLKKDO_00627 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
PLHLKKDO_00628 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PLHLKKDO_00629 3.29e-144 ccpN - - K - - - CBS domain
PLHLKKDO_00630 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PLHLKKDO_00631 4.96e-113 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
PLHLKKDO_00632 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PLHLKKDO_00633 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PLHLKKDO_00634 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PLHLKKDO_00635 1.14e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
PLHLKKDO_00636 5.35e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PLHLKKDO_00637 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PLHLKKDO_00638 1.18e-47 yqfQ - - S - - - YqfQ-like protein
PLHLKKDO_00639 7.7e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PLHLKKDO_00640 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PLHLKKDO_00641 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
PLHLKKDO_00642 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PLHLKKDO_00643 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
PLHLKKDO_00644 1.37e-140 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
PLHLKKDO_00645 4.11e-81 yqfX - - S - - - membrane
PLHLKKDO_00646 7.41e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PLHLKKDO_00647 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
PLHLKKDO_00648 7.86e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
PLHLKKDO_00649 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
PLHLKKDO_00650 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
PLHLKKDO_00651 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
PLHLKKDO_00652 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
PLHLKKDO_00653 1.24e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PLHLKKDO_00654 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PLHLKKDO_00655 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
PLHLKKDO_00656 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PLHLKKDO_00657 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PLHLKKDO_00658 1.09e-93 yqzC - - S - - - YceG-like family
PLHLKKDO_00659 2.81e-67 yqzD - - - - - - -
PLHLKKDO_00661 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
PLHLKKDO_00662 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PLHLKKDO_00663 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PLHLKKDO_00664 3.38e-14 yqgO - - - - - - -
PLHLKKDO_00665 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
PLHLKKDO_00666 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
PLHLKKDO_00667 2.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
PLHLKKDO_00668 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PLHLKKDO_00669 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
PLHLKKDO_00670 6.08e-255 yqgU - - - - - - -
PLHLKKDO_00671 2.99e-65 yqgV - - S - - - Thiamine-binding protein
PLHLKKDO_00672 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
PLHLKKDO_00673 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
PLHLKKDO_00674 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
PLHLKKDO_00675 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
PLHLKKDO_00677 2.49e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PLHLKKDO_00678 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PLHLKKDO_00679 1.51e-233 yqxL - - P - - - Mg2 transporter protein
PLHLKKDO_00680 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
PLHLKKDO_00681 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PLHLKKDO_00682 8.73e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
PLHLKKDO_00683 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
PLHLKKDO_00684 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
PLHLKKDO_00685 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
PLHLKKDO_00686 4.1e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
PLHLKKDO_00687 3.24e-58 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
PLHLKKDO_00688 3.33e-35 yqzE - - S - - - YqzE-like protein
PLHLKKDO_00689 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
PLHLKKDO_00690 8e-156 yqxM - - - ko:K19433 - ko00000 -
PLHLKKDO_00691 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
PLHLKKDO_00692 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
PLHLKKDO_00693 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
PLHLKKDO_00694 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
PLHLKKDO_00695 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
PLHLKKDO_00696 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PLHLKKDO_00697 6.4e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
PLHLKKDO_00698 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PLHLKKDO_00699 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PLHLKKDO_00700 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
PLHLKKDO_00701 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PLHLKKDO_00702 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PLHLKKDO_00703 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PLHLKKDO_00704 5.18e-81 yqhP - - - - - - -
PLHLKKDO_00705 1.21e-219 yqhQ - - S - - - Protein of unknown function (DUF1385)
PLHLKKDO_00706 3.27e-120 yqhR - - S - - - Conserved membrane protein YqhR
PLHLKKDO_00707 4.75e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
PLHLKKDO_00708 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PLHLKKDO_00709 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PLHLKKDO_00710 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
PLHLKKDO_00711 1.66e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
PLHLKKDO_00712 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
PLHLKKDO_00713 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
PLHLKKDO_00714 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
PLHLKKDO_00715 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
PLHLKKDO_00716 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
PLHLKKDO_00717 8.86e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
PLHLKKDO_00718 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
PLHLKKDO_00719 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PLHLKKDO_00720 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PLHLKKDO_00721 1.65e-88 yqhY - - S - - - protein conserved in bacteria
PLHLKKDO_00722 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PLHLKKDO_00723 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PLHLKKDO_00724 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PLHLKKDO_00725 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PLHLKKDO_00726 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PLHLKKDO_00727 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PLHLKKDO_00728 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
PLHLKKDO_00729 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PLHLKKDO_00730 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PLHLKKDO_00731 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
PLHLKKDO_00732 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PLHLKKDO_00734 8.07e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PLHLKKDO_00735 2.26e-37 - - - - - - - -
PLHLKKDO_00736 2.7e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
PLHLKKDO_00737 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PLHLKKDO_00738 2.32e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PLHLKKDO_00739 8.4e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
PLHLKKDO_00740 4.24e-269 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
PLHLKKDO_00741 1.3e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PLHLKKDO_00742 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
PLHLKKDO_00743 4.18e-207 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PLHLKKDO_00744 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
PLHLKKDO_00745 0.0 bkdR - - KT - - - Transcriptional regulator
PLHLKKDO_00746 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
PLHLKKDO_00747 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PLHLKKDO_00748 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
PLHLKKDO_00749 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PLHLKKDO_00750 2.24e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PLHLKKDO_00751 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PLHLKKDO_00752 1.87e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PLHLKKDO_00753 2.6e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
PLHLKKDO_00754 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_00755 1.72e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PLHLKKDO_00756 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
PLHLKKDO_00757 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PLHLKKDO_00758 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PLHLKKDO_00759 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PLHLKKDO_00760 1.09e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
PLHLKKDO_00761 2.41e-128 yqjB - - S - - - protein conserved in bacteria
PLHLKKDO_00763 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
PLHLKKDO_00764 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PLHLKKDO_00765 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
PLHLKKDO_00766 1.2e-181 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
PLHLKKDO_00767 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PLHLKKDO_00768 1.77e-32 yqzJ - - - - - - -
PLHLKKDO_00769 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PLHLKKDO_00770 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PLHLKKDO_00771 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PLHLKKDO_00772 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PLHLKKDO_00773 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PLHLKKDO_00774 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PLHLKKDO_00775 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PLHLKKDO_00776 0.0 rocB - - E - - - arginine degradation protein
PLHLKKDO_00777 1.13e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PLHLKKDO_00778 3.82e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PLHLKKDO_00779 1.62e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_00780 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
PLHLKKDO_00781 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PLHLKKDO_00782 7.43e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PLHLKKDO_00784 2.04e-289 yqjV - - G - - - Major Facilitator Superfamily
PLHLKKDO_00786 3.45e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PLHLKKDO_00787 9.27e-66 yqiX - - S - - - YolD-like protein
PLHLKKDO_00788 5.25e-111 yqjY - - K ko:K06977 - ko00000 acetyltransferase
PLHLKKDO_00789 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
PLHLKKDO_00790 1.37e-249 yqkA - - K - - - GrpB protein
PLHLKKDO_00791 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
PLHLKKDO_00792 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
PLHLKKDO_00793 5.61e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PLHLKKDO_00794 2.69e-25 yqkE - - S - - - Protein of unknown function (DUF3886)
PLHLKKDO_00795 4.4e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
PLHLKKDO_00796 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
PLHLKKDO_00797 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
PLHLKKDO_00798 4.16e-280 yqxK - - L - - - DNA helicase
PLHLKKDO_00799 3.18e-77 ansR - - K - - - Transcriptional regulator
PLHLKKDO_00800 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
PLHLKKDO_00801 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
PLHLKKDO_00802 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PLHLKKDO_00803 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PLHLKKDO_00804 3.08e-43 yqkK - - - - - - -
PLHLKKDO_00805 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PLHLKKDO_00806 3.43e-100 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
PLHLKKDO_00807 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
PLHLKKDO_00808 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
PLHLKKDO_00809 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
PLHLKKDO_00810 3.98e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PLHLKKDO_00811 5.82e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PLHLKKDO_00812 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
PLHLKKDO_00813 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PLHLKKDO_00814 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLHLKKDO_00815 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
PLHLKKDO_00816 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
PLHLKKDO_00817 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
PLHLKKDO_00818 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
PLHLKKDO_00819 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
PLHLKKDO_00820 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
PLHLKKDO_00821 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
PLHLKKDO_00822 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PLHLKKDO_00823 6.29e-192 ypuA - - S - - - Secreted protein
PLHLKKDO_00824 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PLHLKKDO_00829 1.09e-41 - - - S - - - Pfam Transposase IS66
PLHLKKDO_00830 2.61e-34 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PLHLKKDO_00832 3.02e-44 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
PLHLKKDO_00833 3.39e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PLHLKKDO_00834 5.98e-72 ypuD - - - - - - -
PLHLKKDO_00835 7.21e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PLHLKKDO_00836 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
PLHLKKDO_00837 1.48e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PLHLKKDO_00838 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PLHLKKDO_00839 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PLHLKKDO_00840 3.57e-120 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
PLHLKKDO_00841 4.45e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PLHLKKDO_00842 2.85e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PLHLKKDO_00843 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
PLHLKKDO_00844 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PLHLKKDO_00845 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
PLHLKKDO_00846 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
PLHLKKDO_00847 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PLHLKKDO_00848 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PLHLKKDO_00849 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
PLHLKKDO_00850 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PLHLKKDO_00851 1.97e-170 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_00852 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_00853 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_00854 4.91e-246 rsiX - - - - - - -
PLHLKKDO_00855 4.79e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PLHLKKDO_00856 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PLHLKKDO_00857 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PLHLKKDO_00858 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
PLHLKKDO_00859 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
PLHLKKDO_00860 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PLHLKKDO_00861 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
PLHLKKDO_00862 2e-127 ypbE - - M - - - Lysin motif
PLHLKKDO_00863 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
PLHLKKDO_00864 1.02e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
PLHLKKDO_00865 1.86e-134 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PLHLKKDO_00866 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PLHLKKDO_00867 2.68e-226 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
PLHLKKDO_00868 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
PLHLKKDO_00869 6.93e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
PLHLKKDO_00870 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
PLHLKKDO_00871 1.88e-143 ypfA - - M - - - Flagellar protein YcgR
PLHLKKDO_00872 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
PLHLKKDO_00873 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
PLHLKKDO_00874 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
PLHLKKDO_00875 6.61e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PLHLKKDO_00876 1.13e-11 - - - S - - - YpzI-like protein
PLHLKKDO_00877 2.73e-134 yphA - - - - - - -
PLHLKKDO_00878 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
PLHLKKDO_00879 2.06e-38 ypzH - - - - - - -
PLHLKKDO_00880 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PLHLKKDO_00881 4.05e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
PLHLKKDO_00882 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
PLHLKKDO_00883 1.5e-176 yphF - - - - - - -
PLHLKKDO_00884 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PLHLKKDO_00885 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PLHLKKDO_00886 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
PLHLKKDO_00887 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PLHLKKDO_00888 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PLHLKKDO_00889 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PLHLKKDO_00890 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PLHLKKDO_00891 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PLHLKKDO_00892 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
PLHLKKDO_00893 2.91e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PLHLKKDO_00894 3.17e-260 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PLHLKKDO_00895 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PLHLKKDO_00896 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PLHLKKDO_00897 2.03e-228 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PLHLKKDO_00898 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
PLHLKKDO_00899 3.04e-148 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
PLHLKKDO_00900 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PLHLKKDO_00901 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PLHLKKDO_00902 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PLHLKKDO_00903 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
PLHLKKDO_00904 1.64e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PLHLKKDO_00905 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
PLHLKKDO_00906 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
PLHLKKDO_00907 4.75e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
PLHLKKDO_00908 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
PLHLKKDO_00909 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
PLHLKKDO_00910 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
PLHLKKDO_00911 2.82e-126 ypjA - - S - - - membrane
PLHLKKDO_00912 6.84e-183 ypjB - - S - - - sporulation protein
PLHLKKDO_00913 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PLHLKKDO_00914 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
PLHLKKDO_00915 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PLHLKKDO_00916 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
PLHLKKDO_00917 6.61e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
PLHLKKDO_00918 8.18e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
PLHLKKDO_00919 2.5e-277 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PLHLKKDO_00920 1.98e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PLHLKKDO_00921 5.66e-193 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PLHLKKDO_00922 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PLHLKKDO_00923 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PLHLKKDO_00924 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
PLHLKKDO_00925 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
PLHLKKDO_00926 2.27e-103 ypmB - - S - - - protein conserved in bacteria
PLHLKKDO_00927 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PLHLKKDO_00928 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
PLHLKKDO_00929 2.22e-163 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
PLHLKKDO_00930 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PLHLKKDO_00931 6.79e-120 ypoC - - - - - - -
PLHLKKDO_00932 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PLHLKKDO_00933 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PLHLKKDO_00934 1.03e-237 yppC - - S - - - Protein of unknown function (DUF2515)
PLHLKKDO_00937 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
PLHLKKDO_00938 2.27e-11 - - - S - - - YppF-like protein
PLHLKKDO_00939 8.72e-68 yppG - - S - - - YppG-like protein
PLHLKKDO_00940 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PLHLKKDO_00941 1.34e-112 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
PLHLKKDO_00942 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PLHLKKDO_00943 9.82e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
PLHLKKDO_00944 1.19e-128 ypsA - - S - - - Belongs to the UPF0398 family
PLHLKKDO_00945 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PLHLKKDO_00946 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
PLHLKKDO_00948 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
PLHLKKDO_00949 2.79e-177 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_00950 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PLHLKKDO_00951 3.18e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
PLHLKKDO_00952 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
PLHLKKDO_00953 1.2e-131 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
PLHLKKDO_00954 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
PLHLKKDO_00955 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PLHLKKDO_00956 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PLHLKKDO_00957 4.09e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
PLHLKKDO_00958 2.63e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
PLHLKKDO_00959 9.54e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
PLHLKKDO_00961 0.0 ypbR - - S - - - Dynamin family
PLHLKKDO_00962 2.27e-49 ypbS - - S - - - Protein of unknown function (DUF2533)
PLHLKKDO_00963 1.08e-11 - - - - - - - -
PLHLKKDO_00964 2.64e-212 ypcP - - L - - - 5'3' exonuclease
PLHLKKDO_00965 5.23e-05 - - - - ko:K06429 - ko00000 -
PLHLKKDO_00966 6.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
PLHLKKDO_00967 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PLHLKKDO_00968 1.9e-161 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
PLHLKKDO_00969 7.99e-41 ypeQ - - S - - - Zinc-finger
PLHLKKDO_00970 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
PLHLKKDO_00971 1.17e-22 degR - - - - - - -
PLHLKKDO_00972 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
PLHLKKDO_00973 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PLHLKKDO_00974 1.49e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLHLKKDO_00975 7.69e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
PLHLKKDO_00976 2.6e-135 yagB - - S ko:K06950 - ko00000 phosphohydrolase
PLHLKKDO_00977 2.83e-204 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
PLHLKKDO_00978 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
PLHLKKDO_00979 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
PLHLKKDO_00980 2.81e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
PLHLKKDO_00981 1.16e-146 ypjP - - S - - - YpjP-like protein
PLHLKKDO_00982 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
PLHLKKDO_00983 9.52e-199 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PLHLKKDO_00984 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PLHLKKDO_00985 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PLHLKKDO_00986 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
PLHLKKDO_00987 1.4e-236 yplP - - K - - - Transcriptional regulator
PLHLKKDO_00988 1.73e-308 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PLHLKKDO_00989 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
PLHLKKDO_00990 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PLHLKKDO_00991 1.05e-177 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
PLHLKKDO_00992 6.8e-129 ypmS - - S - - - protein conserved in bacteria
PLHLKKDO_00993 2.13e-40 ypmT - - S - - - Uncharacterized ympT
PLHLKKDO_00994 1.65e-288 mepA - - V - - - MATE efflux family protein
PLHLKKDO_00995 4.14e-94 ypoP - - K - - - transcriptional
PLHLKKDO_00996 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PLHLKKDO_00997 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
PLHLKKDO_00998 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PLHLKKDO_00999 1.1e-277 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
PLHLKKDO_01000 3.86e-236 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
PLHLKKDO_01001 1.12e-85 cgeA - - - ko:K06319 - ko00000 -
PLHLKKDO_01002 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
PLHLKKDO_01003 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
PLHLKKDO_01004 3.98e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
PLHLKKDO_01006 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PLHLKKDO_01007 3.41e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PLHLKKDO_01008 5.46e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PLHLKKDO_01009 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
PLHLKKDO_01010 1.84e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
PLHLKKDO_01011 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
PLHLKKDO_01012 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
PLHLKKDO_01013 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
PLHLKKDO_01014 1.29e-159 yodN - - - - - - -
PLHLKKDO_01016 5.18e-34 yozD - - S - - - YozD-like protein
PLHLKKDO_01017 6.67e-137 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
PLHLKKDO_01018 1.17e-71 yodL - - S - - - YodL-like
PLHLKKDO_01019 2.08e-12 - - - - - - - -
PLHLKKDO_01020 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
PLHLKKDO_01021 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PLHLKKDO_01022 2.93e-42 yodI - - - - - - -
PLHLKKDO_01023 3.69e-167 yodH - - Q - - - Methyltransferase
PLHLKKDO_01024 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PLHLKKDO_01025 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLHLKKDO_01026 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
PLHLKKDO_01027 3.38e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PLHLKKDO_01028 3.76e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
PLHLKKDO_01029 1.92e-140 yodC - - C - - - nitroreductase
PLHLKKDO_01030 2.63e-73 yodB - - K - - - transcriptional
PLHLKKDO_01031 2.3e-83 iolK - - S - - - tautomerase
PLHLKKDO_01032 9.24e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
PLHLKKDO_01033 1.95e-14 - - - - - - - -
PLHLKKDO_01034 1.89e-100 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
PLHLKKDO_01035 5.49e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
PLHLKKDO_01036 1.85e-58 - - - - - - - -
PLHLKKDO_01037 2.72e-78 yojF - - S - - - Protein of unknown function (DUF1806)
PLHLKKDO_01038 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
PLHLKKDO_01039 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PLHLKKDO_01040 1.02e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
PLHLKKDO_01042 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PLHLKKDO_01043 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
PLHLKKDO_01044 1.02e-264 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PLHLKKDO_01045 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PLHLKKDO_01046 8.98e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
PLHLKKDO_01047 0.0 yojO - - P - - - Von Willebrand factor
PLHLKKDO_01048 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PLHLKKDO_01049 3.16e-265 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PLHLKKDO_01050 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
PLHLKKDO_01051 6.18e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PLHLKKDO_01052 2.64e-209 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
PLHLKKDO_01053 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
PLHLKKDO_01054 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PLHLKKDO_01055 1.91e-42 yozC - - - - - - -
PLHLKKDO_01056 2.17e-74 yozO - - S - - - Bacterial PH domain
PLHLKKDO_01057 1.83e-49 yocN - - - - - - -
PLHLKKDO_01058 2.94e-55 yozN - - - - - - -
PLHLKKDO_01059 3.15e-113 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PLHLKKDO_01060 3.93e-41 - - - - - - - -
PLHLKKDO_01061 1.75e-69 yocL - - - - - - -
PLHLKKDO_01062 2.87e-107 yocK - - T - - - general stress protein
PLHLKKDO_01063 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PLHLKKDO_01064 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PLHLKKDO_01065 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
PLHLKKDO_01066 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PLHLKKDO_01067 2.88e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_01068 1.34e-256 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
PLHLKKDO_01069 1.58e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
PLHLKKDO_01070 1.08e-121 yocC - - - - - - -
PLHLKKDO_01071 2.6e-185 - - - - - - - -
PLHLKKDO_01072 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
PLHLKKDO_01073 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PLHLKKDO_01074 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
PLHLKKDO_01075 7.51e-74 yobW - - - - - - -
PLHLKKDO_01076 1.25e-33 yobW - - - - - - -
PLHLKKDO_01077 1.09e-224 yobV - - K - - - WYL domain
PLHLKKDO_01078 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
PLHLKKDO_01079 1.29e-167 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PLHLKKDO_01080 3.09e-127 yobS - - K - - - Transcriptional regulator
PLHLKKDO_01081 1.24e-181 - - - J - - - FR47-like protein
PLHLKKDO_01082 1.82e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
PLHLKKDO_01083 2.04e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
PLHLKKDO_01084 0.0 yobO - - M - - - Pectate lyase superfamily protein
PLHLKKDO_01085 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
PLHLKKDO_01086 9.75e-133 yokH - - G - - - SMI1 / KNR4 family
PLHLKKDO_01087 1.08e-46 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PLHLKKDO_01091 4.99e-08 - - - K - - - Helix-turn-helix
PLHLKKDO_01092 6.27e-51 - - - S - - - TM2 domain
PLHLKKDO_01093 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
PLHLKKDO_01094 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
PLHLKKDO_01097 2.54e-215 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
PLHLKKDO_01098 1.7e-147 lin0465 - - S - - - DJ-1/PfpI family
PLHLKKDO_01099 3.13e-99 yoaW - - - - - - -
PLHLKKDO_01100 1.24e-199 yoaV - - EG - - - EamA-like transporter family
PLHLKKDO_01101 7.78e-202 yoaU - - K - - - LysR substrate binding domain
PLHLKKDO_01102 7.76e-189 yoaT - - S - - - Protein of unknown function (DUF817)
PLHLKKDO_01103 6.07e-49 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_01104 2.65e-97 yoaS - - S - - - Protein of unknown function (DUF2975)
PLHLKKDO_01105 1.04e-217 yoaR - - V - - - vancomycin resistance protein
PLHLKKDO_01106 2.27e-114 - - - - - - - -
PLHLKKDO_01108 1.88e-67 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
PLHLKKDO_01109 5.48e-183 yoaP - - K - - - YoaP-like
PLHLKKDO_01111 8.53e-291 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PLHLKKDO_01114 2.42e-169 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
PLHLKKDO_01115 2.89e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
PLHLKKDO_01116 1.47e-144 yoaK - - S - - - Membrane
PLHLKKDO_01117 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
PLHLKKDO_01118 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
PLHLKKDO_01119 3.89e-283 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
PLHLKKDO_01120 1.13e-59 - - - S - - - Protein of unknown function (DUF4025)
PLHLKKDO_01121 1.46e-19 - - - - - - - -
PLHLKKDO_01123 2.08e-44 yoaF - - - - - - -
PLHLKKDO_01124 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PLHLKKDO_01125 7.91e-233 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PLHLKKDO_01126 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
PLHLKKDO_01127 8.38e-298 yoaB - - EGP - - - the major facilitator superfamily
PLHLKKDO_01128 6.15e-64 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PLHLKKDO_01129 6.16e-165 yoxB - - - - - - -
PLHLKKDO_01130 9.43e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
PLHLKKDO_01131 3.23e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_01132 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PLHLKKDO_01133 3.18e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PLHLKKDO_01134 3.86e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PLHLKKDO_01135 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_01136 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
PLHLKKDO_01137 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PLHLKKDO_01138 1.9e-233 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PLHLKKDO_01139 5.67e-197 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_01140 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PLHLKKDO_01141 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
PLHLKKDO_01142 1.14e-124 - - - L - - - Integrase
PLHLKKDO_01144 2.91e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
PLHLKKDO_01145 9.8e-313 yoeA - - V - - - MATE efflux family protein
PLHLKKDO_01146 5.75e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
PLHLKKDO_01147 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PLHLKKDO_01148 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_01149 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_01150 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_01151 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_01152 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
PLHLKKDO_01153 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
PLHLKKDO_01154 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
PLHLKKDO_01155 5.35e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PLHLKKDO_01156 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PLHLKKDO_01157 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
PLHLKKDO_01158 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
PLHLKKDO_01159 6.73e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
PLHLKKDO_01160 2.46e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
PLHLKKDO_01161 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PLHLKKDO_01162 1.28e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
PLHLKKDO_01163 2.01e-134 yngC - - S - - - membrane-associated protein
PLHLKKDO_01164 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PLHLKKDO_01165 4.94e-103 yngA - - S - - - membrane
PLHLKKDO_01166 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PLHLKKDO_01167 3.13e-313 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
PLHLKKDO_01169 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
PLHLKKDO_01170 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PLHLKKDO_01171 1.06e-75 ynfC - - - - - - -
PLHLKKDO_01172 1.82e-18 - - - - - - - -
PLHLKKDO_01173 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PLHLKKDO_01174 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PLHLKKDO_01175 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
PLHLKKDO_01176 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PLHLKKDO_01177 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
PLHLKKDO_01178 1.63e-71 yneQ - - - - - - -
PLHLKKDO_01179 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
PLHLKKDO_01180 1.9e-47 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
PLHLKKDO_01182 9.26e-10 - - - S - - - Fur-regulated basic protein B
PLHLKKDO_01183 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PLHLKKDO_01184 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PLHLKKDO_01185 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
PLHLKKDO_01186 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
PLHLKKDO_01187 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
PLHLKKDO_01188 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
PLHLKKDO_01189 7.21e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
PLHLKKDO_01190 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
PLHLKKDO_01191 1.68e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
PLHLKKDO_01192 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
PLHLKKDO_01193 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
PLHLKKDO_01194 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
PLHLKKDO_01195 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PLHLKKDO_01196 1.15e-43 ynzC - - S - - - UPF0291 protein
PLHLKKDO_01197 2.29e-144 yneB - - L - - - resolvase
PLHLKKDO_01198 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PLHLKKDO_01199 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PLHLKKDO_01200 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PLHLKKDO_01201 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
PLHLKKDO_01202 3.26e-175 yndL - - S - - - Replication protein
PLHLKKDO_01204 0.0 yndJ - - S - - - YndJ-like protein
PLHLKKDO_01205 8.49e-150 - - - S - - - Domain of unknown function (DUF4166)
PLHLKKDO_01206 1.86e-170 yndG - - S - - - DoxX-like family
PLHLKKDO_01207 9.24e-288 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
PLHLKKDO_01208 1.87e-248 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
PLHLKKDO_01209 2.21e-230 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PLHLKKDO_01210 5.03e-96 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PLHLKKDO_01213 1.05e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
PLHLKKDO_01214 8.92e-96 - - - - - - - -
PLHLKKDO_01215 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
PLHLKKDO_01218 3.27e-134 - - - S - - - Domain of unknown function, YrpD
PLHLKKDO_01220 3.91e-210 - - - S - - - Thymidylate synthase
PLHLKKDO_01223 7.54e-22 - - - - - - - -
PLHLKKDO_01224 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
PLHLKKDO_01225 2.83e-109 - - - S - - - Protein of unknown function (DUF2691)
PLHLKKDO_01226 1.77e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PLHLKKDO_01227 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PLHLKKDO_01228 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
PLHLKKDO_01229 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
PLHLKKDO_01230 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
PLHLKKDO_01231 1.18e-273 xylR - - GK - - - ROK family
PLHLKKDO_01232 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PLHLKKDO_01233 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
PLHLKKDO_01234 1.13e-49 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
PLHLKKDO_01235 2.04e-99 - - - E - - - phosphoribosylanthranilate isomerase activity
PLHLKKDO_01238 5.66e-145 - - - S - - - Domain of unknown function (DUF3885)
PLHLKKDO_01239 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PLHLKKDO_01241 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PLHLKKDO_01242 2.28e-93 - - - S - - - CAAX protease self-immunity
PLHLKKDO_01243 8.3e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
PLHLKKDO_01245 9e-274 - - - H - - - N-terminal domain of galactosyltransferase
PLHLKKDO_01246 6.07e-248 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PLHLKKDO_01247 3.91e-154 - - - H - - - Methionine biosynthesis protein MetW
PLHLKKDO_01248 1.36e-119 - - - M - - - Glycosyltransferase like family
PLHLKKDO_01249 5.72e-80 - - - Q - - - Collagen triple helix repeat (20 copies)
PLHLKKDO_01252 3.06e-14 - - - - - - - -
PLHLKKDO_01253 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PLHLKKDO_01254 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
PLHLKKDO_01255 4.78e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PLHLKKDO_01256 7.4e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PLHLKKDO_01257 1.09e-88 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
PLHLKKDO_01258 1.25e-306 - - - L ko:K06400 - ko00000 Recombinase
PLHLKKDO_01260 1.51e-121 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PLHLKKDO_01261 3.44e-06 - - - K - - - Cro/C1-type HTH DNA-binding domain
PLHLKKDO_01270 8.83e-205 - - - S - - - Calcineurin-like phosphoesterase
PLHLKKDO_01271 6.2e-39 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
PLHLKKDO_01274 1.35e-44 - - - - - - - -
PLHLKKDO_01276 9.36e-39 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PLHLKKDO_01277 5.12e-206 - - - S - - - Thymidylate synthase
PLHLKKDO_01282 1.42e-95 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
PLHLKKDO_01284 1.53e-47 - - - O - - - Glutaredoxin
PLHLKKDO_01285 2.01e-81 - - - S - - - Ribonucleotide reductase, small chain
PLHLKKDO_01286 8.79e-125 - - - L - - - HNH endonuclease
PLHLKKDO_01287 1.01e-135 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLHLKKDO_01289 4.3e-248 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLHLKKDO_01290 9e-157 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLHLKKDO_01291 1.67e-86 - - - S - - - NrdI Flavodoxin like
PLHLKKDO_01305 2.52e-26 - - - S - - - Calcineurin-like phosphoesterase
PLHLKKDO_01310 2.01e-184 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
PLHLKKDO_01313 1.3e-104 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
PLHLKKDO_01318 7.76e-147 - - - S - - - protein conserved in bacteria
PLHLKKDO_01319 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
PLHLKKDO_01320 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PLHLKKDO_01321 1.11e-284 - - - L - - - DNA primase activity
PLHLKKDO_01322 0.0 - - - J - - - DnaB-like helicase C terminal domain
PLHLKKDO_01323 7.45e-111 - - - - - - - -
PLHLKKDO_01324 5.21e-228 - - - L - - - AAA domain
PLHLKKDO_01325 3.18e-208 - - - - - - - -
PLHLKKDO_01327 6.61e-34 - - - S ko:K06327 - ko00000 Inner spore coat protein D
PLHLKKDO_01332 1.93e-209 - - - - - - - -
PLHLKKDO_01334 2.82e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
PLHLKKDO_01335 5.86e-187 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
PLHLKKDO_01339 2.73e-93 - - - - - - - -
PLHLKKDO_01347 1.21e-06 - - - S - - - YopX protein
PLHLKKDO_01352 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_01353 2.89e-226 - - - - - - - -
PLHLKKDO_01354 0.0 - - - S - - - DNA-sulfur modification-associated
PLHLKKDO_01355 1.96e-252 - - - L - - - Belongs to the 'phage' integrase family
PLHLKKDO_01360 6.47e-134 - - - - - - - -
PLHLKKDO_01361 1.49e-101 - - - - - - - -
PLHLKKDO_01362 2.94e-08 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil DNA glycosylase superfamily
PLHLKKDO_01366 1.98e-13 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PLHLKKDO_01370 1.64e-38 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PLHLKKDO_01372 2.98e-96 - - - - - - - -
PLHLKKDO_01376 4.19e-252 - - - L - - - Domain of unknown function (DUF4942)
PLHLKKDO_01377 6.19e-06 - - - L - - - SNF2 family N-terminal domain
PLHLKKDO_01378 6.38e-150 - - - - - - - -
PLHLKKDO_01379 5.37e-93 - - - - - - - -
PLHLKKDO_01382 0.0 - - - S - - - RNA-directed RNA polymerase activity
PLHLKKDO_01383 3.87e-114 - - - - - - - -
PLHLKKDO_01384 1.73e-47 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PLHLKKDO_01385 6.2e-303 - - - - - - - -
PLHLKKDO_01388 4.74e-286 - - - S - - - hydrolase activity
PLHLKKDO_01392 1.55e-130 - - - - - - - -
PLHLKKDO_01396 2.6e-86 - - - - - - - -
PLHLKKDO_01399 1.28e-86 - - - - - - - -
PLHLKKDO_01400 2.6e-101 - - - - - - - -
PLHLKKDO_01401 1.09e-115 - - - - - - - -
PLHLKKDO_01402 6.41e-75 - - - - - - - -
PLHLKKDO_01405 3.95e-61 - - - - - - - -
PLHLKKDO_01406 2.43e-41 - - - S - - - Domain of unknown function (DUF2479)
PLHLKKDO_01409 1.85e-125 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
PLHLKKDO_01410 4.59e-70 - - - - - - - -
PLHLKKDO_01411 2.47e-76 - - - - - - - -
PLHLKKDO_01412 4.56e-243 - - - A - - - Belongs to the 'phage' integrase family
PLHLKKDO_01416 2.37e-151 - - - - - - - -
PLHLKKDO_01417 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PLHLKKDO_01418 1.52e-109 - - - S - - - Phage tail protein
PLHLKKDO_01419 0.0 - - - S - - - Pfam Transposase IS66
PLHLKKDO_01420 2.8e-169 - - - - - - - -
PLHLKKDO_01421 1.02e-289 - - - M - - - Pectate lyase superfamily protein
PLHLKKDO_01422 2.82e-93 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PLHLKKDO_01423 1.42e-43 bhlA - - S - - - BhlA holin family
PLHLKKDO_01424 3.04e-53 - - - S - - - SPP1 phage holin
PLHLKKDO_01425 5.12e-96 - - - O ko:K03611 - ko00000,ko03110 protein disulfide oxidoreductase activity
PLHLKKDO_01426 1.66e-306 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PLHLKKDO_01427 3.44e-91 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 cell redox homeostasis
PLHLKKDO_01428 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 Peptidase C39 family
PLHLKKDO_01430 5.06e-298 - - - S - - - damaged DNA binding
PLHLKKDO_01431 9e-72 - - - S - - - YolD-like protein
PLHLKKDO_01435 5.77e-124 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PLHLKKDO_01436 2.81e-117 yokK - - S - - - SMI1 / KNR4 family
PLHLKKDO_01437 8.76e-99 - - - S - - - SMI1-KNR4 cell-wall
PLHLKKDO_01438 5.39e-216 - - - S - - - Bacterial EndoU nuclease
PLHLKKDO_01439 4.13e-84 - - - G - - - SMI1-KNR4 cell-wall
PLHLKKDO_01440 1.32e-168 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
PLHLKKDO_01441 7.89e-105 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
PLHLKKDO_01443 3.46e-123 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
PLHLKKDO_01444 5.49e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PLHLKKDO_01445 1.29e-140 - - - - - - - -
PLHLKKDO_01446 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLHLKKDO_01447 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLHLKKDO_01448 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
PLHLKKDO_01449 1.2e-30 ymzA - - - - - - -
PLHLKKDO_01450 1.63e-31 - - - - - - - -
PLHLKKDO_01451 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PLHLKKDO_01452 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PLHLKKDO_01453 5.41e-76 ymaF - - S - - - YmaF family
PLHLKKDO_01455 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PLHLKKDO_01456 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
PLHLKKDO_01457 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
PLHLKKDO_01458 3.96e-163 ymaC - - S - - - Replication protein
PLHLKKDO_01460 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
PLHLKKDO_01461 1.27e-205 - - - S - - - Metallo-beta-lactamase superfamily
PLHLKKDO_01462 8.03e-81 ymzB - - - - - - -
PLHLKKDO_01463 6.85e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PLHLKKDO_01464 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
PLHLKKDO_01465 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PLHLKKDO_01466 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PLHLKKDO_01467 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PLHLKKDO_01468 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PLHLKKDO_01469 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
PLHLKKDO_01470 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
PLHLKKDO_01471 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
PLHLKKDO_01472 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PLHLKKDO_01473 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
PLHLKKDO_01474 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PLHLKKDO_01475 2.42e-238 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
PLHLKKDO_01476 4.37e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PLHLKKDO_01477 6.66e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
PLHLKKDO_01478 2.94e-141 pksA - - K - - - Transcriptional regulator
PLHLKKDO_01479 6.55e-126 ymcC - - S - - - Membrane
PLHLKKDO_01480 2.72e-91 - - - S - - - Regulatory protein YrvL
PLHLKKDO_01482 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PLHLKKDO_01483 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PLHLKKDO_01484 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
PLHLKKDO_01485 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
PLHLKKDO_01486 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PLHLKKDO_01487 5.89e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PLHLKKDO_01488 1.44e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PLHLKKDO_01489 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
PLHLKKDO_01490 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
PLHLKKDO_01491 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
PLHLKKDO_01492 9.84e-281 pbpX - - V - - - Beta-lactamase
PLHLKKDO_01493 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PLHLKKDO_01494 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
PLHLKKDO_01495 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PLHLKKDO_01496 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
PLHLKKDO_01497 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
PLHLKKDO_01498 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
PLHLKKDO_01499 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PLHLKKDO_01500 6.8e-309 ymfH - - S - - - zinc protease
PLHLKKDO_01501 1.35e-298 albE - - S - - - Peptidase M16
PLHLKKDO_01502 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_01503 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_01504 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PLHLKKDO_01505 4.94e-44 - - - S - - - YlzJ-like protein
PLHLKKDO_01506 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
PLHLKKDO_01507 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PLHLKKDO_01508 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PLHLKKDO_01509 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PLHLKKDO_01510 5.56e-246 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PLHLKKDO_01511 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PLHLKKDO_01512 1.52e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
PLHLKKDO_01513 1.53e-56 ymxH - - S - - - YlmC YmxH family
PLHLKKDO_01514 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
PLHLKKDO_01515 9.38e-229 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
PLHLKKDO_01516 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PLHLKKDO_01517 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PLHLKKDO_01518 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PLHLKKDO_01519 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PLHLKKDO_01520 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PLHLKKDO_01521 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
PLHLKKDO_01522 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PLHLKKDO_01523 6.16e-63 ylxQ - - J - - - ribosomal protein
PLHLKKDO_01524 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
PLHLKKDO_01525 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PLHLKKDO_01526 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
PLHLKKDO_01527 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PLHLKKDO_01528 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PLHLKKDO_01529 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
PLHLKKDO_01530 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PLHLKKDO_01531 1.65e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PLHLKKDO_01532 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PLHLKKDO_01533 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PLHLKKDO_01534 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PLHLKKDO_01535 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PLHLKKDO_01536 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PLHLKKDO_01537 1.34e-98 ylxL - - - - - - -
PLHLKKDO_01538 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLHLKKDO_01539 9.58e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PLHLKKDO_01540 1.45e-143 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PLHLKKDO_01541 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
PLHLKKDO_01542 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
PLHLKKDO_01543 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PLHLKKDO_01544 1.55e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
PLHLKKDO_01545 1.14e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
PLHLKKDO_01546 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PLHLKKDO_01547 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PLHLKKDO_01548 2.09e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
PLHLKKDO_01549 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
PLHLKKDO_01550 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
PLHLKKDO_01551 1.3e-135 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
PLHLKKDO_01552 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
PLHLKKDO_01553 7.96e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PLHLKKDO_01554 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PLHLKKDO_01555 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
PLHLKKDO_01556 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
PLHLKKDO_01557 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
PLHLKKDO_01558 1.17e-307 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
PLHLKKDO_01559 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
PLHLKKDO_01560 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
PLHLKKDO_01561 1.74e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PLHLKKDO_01562 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
PLHLKKDO_01563 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PLHLKKDO_01564 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
PLHLKKDO_01565 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
PLHLKKDO_01566 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
PLHLKKDO_01567 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PLHLKKDO_01568 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PLHLKKDO_01569 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PLHLKKDO_01570 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PLHLKKDO_01571 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
PLHLKKDO_01572 3.67e-312 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PLHLKKDO_01573 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PLHLKKDO_01574 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
PLHLKKDO_01575 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PLHLKKDO_01576 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PLHLKKDO_01577 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
PLHLKKDO_01578 0.0 ylqG - - - - - - -
PLHLKKDO_01579 1.37e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PLHLKKDO_01580 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PLHLKKDO_01581 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PLHLKKDO_01582 6.9e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PLHLKKDO_01583 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PLHLKKDO_01584 3.41e-80 ylqD - - S - - - YlqD protein
PLHLKKDO_01585 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
PLHLKKDO_01586 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PLHLKKDO_01587 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PLHLKKDO_01588 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PLHLKKDO_01589 1.67e-114 - - - - - - - -
PLHLKKDO_01590 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PLHLKKDO_01591 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PLHLKKDO_01592 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PLHLKKDO_01593 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PLHLKKDO_01594 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PLHLKKDO_01595 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PLHLKKDO_01596 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PLHLKKDO_01597 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PLHLKKDO_01598 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PLHLKKDO_01599 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PLHLKKDO_01600 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PLHLKKDO_01601 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
PLHLKKDO_01602 3.65e-78 yloU - - S - - - protein conserved in bacteria
PLHLKKDO_01603 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
PLHLKKDO_01604 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PLHLKKDO_01605 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PLHLKKDO_01606 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PLHLKKDO_01607 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
PLHLKKDO_01608 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
PLHLKKDO_01609 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PLHLKKDO_01610 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PLHLKKDO_01611 1.67e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PLHLKKDO_01612 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PLHLKKDO_01613 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PLHLKKDO_01614 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PLHLKKDO_01615 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PLHLKKDO_01616 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PLHLKKDO_01617 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
PLHLKKDO_01618 8.41e-202 yloC - - S - - - stress-induced protein
PLHLKKDO_01619 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
PLHLKKDO_01620 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
PLHLKKDO_01621 6.53e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
PLHLKKDO_01622 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
PLHLKKDO_01623 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PLHLKKDO_01624 3.76e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
PLHLKKDO_01625 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
PLHLKKDO_01626 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
PLHLKKDO_01627 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
PLHLKKDO_01629 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PLHLKKDO_01630 8.94e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PLHLKKDO_01631 6.05e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PLHLKKDO_01632 3.69e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PLHLKKDO_01633 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
PLHLKKDO_01634 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PLHLKKDO_01635 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PLHLKKDO_01636 7.29e-214 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PLHLKKDO_01637 5.27e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
PLHLKKDO_01638 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PLHLKKDO_01639 1.01e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PLHLKKDO_01640 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PLHLKKDO_01641 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
PLHLKKDO_01642 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PLHLKKDO_01643 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
PLHLKKDO_01644 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
PLHLKKDO_01645 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
PLHLKKDO_01646 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PLHLKKDO_01647 1.05e-160 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PLHLKKDO_01648 1.78e-201 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
PLHLKKDO_01649 3.58e-51 ylmC - - S - - - sporulation protein
PLHLKKDO_01650 8.98e-315 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
PLHLKKDO_01651 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PLHLKKDO_01652 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLHLKKDO_01653 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLHLKKDO_01654 6.04e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PLHLKKDO_01655 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
PLHLKKDO_01656 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PLHLKKDO_01657 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PLHLKKDO_01658 5.37e-76 sbp - - S - - - small basic protein
PLHLKKDO_01659 1.03e-123 ylxX - - S - - - protein conserved in bacteria
PLHLKKDO_01660 4.5e-142 ylxW - - S - - - protein conserved in bacteria
PLHLKKDO_01661 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PLHLKKDO_01662 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
PLHLKKDO_01663 7.74e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PLHLKKDO_01664 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PLHLKKDO_01665 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PLHLKKDO_01666 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PLHLKKDO_01667 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PLHLKKDO_01668 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
PLHLKKDO_01669 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PLHLKKDO_01670 3.42e-68 ftsL - - D - - - Essential cell division protein
PLHLKKDO_01671 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PLHLKKDO_01672 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
PLHLKKDO_01673 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PLHLKKDO_01674 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PLHLKKDO_01675 1.33e-115 ylbP - - K - - - n-acetyltransferase
PLHLKKDO_01676 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PLHLKKDO_01677 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
PLHLKKDO_01678 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
PLHLKKDO_01680 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
PLHLKKDO_01681 1.58e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PLHLKKDO_01682 3.64e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PLHLKKDO_01683 3.87e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
PLHLKKDO_01684 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PLHLKKDO_01685 3.51e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
PLHLKKDO_01686 5.1e-51 ylbG - - S - - - UPF0298 protein
PLHLKKDO_01687 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
PLHLKKDO_01688 1.73e-48 ylbE - - S - - - YlbE-like protein
PLHLKKDO_01689 3.24e-89 ylbD - - S - - - Putative coat protein
PLHLKKDO_01690 1.53e-256 ylbC - - S - - - protein with SCP PR1 domains
PLHLKKDO_01691 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
PLHLKKDO_01692 1.61e-81 ylbA - - S - - - YugN-like family
PLHLKKDO_01693 1.48e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
PLHLKKDO_01694 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PLHLKKDO_01695 6.17e-144 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PLHLKKDO_01696 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PLHLKKDO_01697 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PLHLKKDO_01698 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PLHLKKDO_01699 2e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PLHLKKDO_01700 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PLHLKKDO_01701 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PLHLKKDO_01702 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
PLHLKKDO_01703 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PLHLKKDO_01704 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PLHLKKDO_01705 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
PLHLKKDO_01706 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PLHLKKDO_01707 8.92e-44 ylaI - - S - - - protein conserved in bacteria
PLHLKKDO_01708 4.4e-63 ylaH - - S - - - YlaH-like protein
PLHLKKDO_01709 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
PLHLKKDO_01710 1.56e-30 - - - S - - - Family of unknown function (DUF5325)
PLHLKKDO_01711 1.31e-54 ylaE - - - - - - -
PLHLKKDO_01713 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_01714 2.79e-54 ylaB - - - - - - -
PLHLKKDO_01715 0.0 ylaA - - - - - - -
PLHLKKDO_01716 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
PLHLKKDO_01717 5.82e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PLHLKKDO_01718 2.45e-99 ykzC - - S - - - Acetyltransferase (GNAT) family
PLHLKKDO_01719 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
PLHLKKDO_01720 4.48e-35 ykzI - - - - - - -
PLHLKKDO_01721 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
PLHLKKDO_01722 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
PLHLKKDO_01723 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
PLHLKKDO_01724 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
PLHLKKDO_01725 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PLHLKKDO_01726 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PLHLKKDO_01727 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PLHLKKDO_01728 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PLHLKKDO_01729 2.22e-140 ykyA - - L - - - Putative cell-wall binding lipoprotein
PLHLKKDO_01730 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PLHLKKDO_01731 2.29e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PLHLKKDO_01732 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
PLHLKKDO_01733 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
PLHLKKDO_01734 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PLHLKKDO_01735 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PLHLKKDO_01736 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PLHLKKDO_01737 8.76e-201 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
PLHLKKDO_01738 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PLHLKKDO_01739 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
PLHLKKDO_01740 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
PLHLKKDO_01741 1.09e-18 - - - S - - - Uncharacterized protein YkpC
PLHLKKDO_01742 5.94e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
PLHLKKDO_01743 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PLHLKKDO_01744 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PLHLKKDO_01745 5.43e-52 ykoA - - - - - - -
PLHLKKDO_01746 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PLHLKKDO_01747 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PLHLKKDO_01748 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
PLHLKKDO_01749 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_01750 1.65e-266 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PLHLKKDO_01751 8.67e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_01752 2.34e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLHLKKDO_01753 7.59e-150 yknW - - S - - - Yip1 domain
PLHLKKDO_01754 4.62e-182 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PLHLKKDO_01755 2.93e-214 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PLHLKKDO_01756 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PLHLKKDO_01757 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PLHLKKDO_01758 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
PLHLKKDO_01759 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
PLHLKKDO_01760 1.44e-311 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
PLHLKKDO_01761 2.54e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PLHLKKDO_01762 2.64e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PLHLKKDO_01763 8.49e-201 yknT - - - ko:K06437 - ko00000 -
PLHLKKDO_01764 1.78e-120 rok - - K - - - Repressor of ComK
PLHLKKDO_01765 1.47e-104 ykuV - - CO - - - thiol-disulfide
PLHLKKDO_01766 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
PLHLKKDO_01767 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
PLHLKKDO_01768 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
PLHLKKDO_01769 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PLHLKKDO_01770 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PLHLKKDO_01771 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
PLHLKKDO_01772 1.33e-226 ykuO - - - - - - -
PLHLKKDO_01773 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
PLHLKKDO_01774 6.52e-216 ccpC - - K - - - Transcriptional regulator
PLHLKKDO_01775 5.15e-100 ykuL - - S - - - CBS domain
PLHLKKDO_01776 7.83e-38 ykzF - - S - - - Antirepressor AbbA
PLHLKKDO_01777 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
PLHLKKDO_01778 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
PLHLKKDO_01779 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
PLHLKKDO_01780 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_01781 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
PLHLKKDO_01782 5.84e-115 ykuD - - S - - - protein conserved in bacteria
PLHLKKDO_01783 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_01784 3.71e-110 ykyB - - S - - - YkyB-like protein
PLHLKKDO_01785 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
PLHLKKDO_01786 1.05e-22 - - - - - - - -
PLHLKKDO_01787 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PLHLKKDO_01788 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_01789 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PLHLKKDO_01790 2.97e-169 ykwD - - J - - - protein with SCP PR1 domains
PLHLKKDO_01791 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PLHLKKDO_01792 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PLHLKKDO_01793 1.06e-167 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PLHLKKDO_01794 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
PLHLKKDO_01795 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_01796 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PLHLKKDO_01797 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
PLHLKKDO_01798 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_01799 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
PLHLKKDO_01801 5.43e-229 ykvZ - - K - - - Transcriptional regulator
PLHLKKDO_01802 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PLHLKKDO_01803 3.99e-09 - - - - - - - -
PLHLKKDO_01804 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PLHLKKDO_01805 5.57e-115 stoA - - CO - - - thiol-disulfide
PLHLKKDO_01806 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PLHLKKDO_01807 1.76e-139 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
PLHLKKDO_01808 2.6e-39 - - - - - - - -
PLHLKKDO_01809 5.43e-35 ykvS - - S - - - protein conserved in bacteria
PLHLKKDO_01810 2.57e-60 ykvR - - S - - - Protein of unknown function (DUF3219)
PLHLKKDO_01811 1.88e-201 - - - G - - - Glycosyl hydrolases family 18
PLHLKKDO_01812 1e-43 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
PLHLKKDO_01813 7.08e-271 - - - M - - - Glycosyl transferases group 1
PLHLKKDO_01814 1.89e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PLHLKKDO_01815 3.53e-81 ykvN - - K - - - Transcriptional regulator
PLHLKKDO_01816 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PLHLKKDO_01817 2.93e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PLHLKKDO_01818 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
PLHLKKDO_01819 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PLHLKKDO_01820 3.35e-227 ykvI - - S - - - membrane
PLHLKKDO_01821 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
PLHLKKDO_01822 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PLHLKKDO_01823 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PLHLKKDO_01824 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
PLHLKKDO_01825 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PLHLKKDO_01826 4.81e-94 eag - - - - - - -
PLHLKKDO_01828 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
PLHLKKDO_01829 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PLHLKKDO_01830 3.71e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PLHLKKDO_01831 2.06e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PLHLKKDO_01832 5.62e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PLHLKKDO_01833 6.56e-294 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PLHLKKDO_01834 1.64e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PLHLKKDO_01835 9.63e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PLHLKKDO_01836 4.44e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PLHLKKDO_01838 1.6e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PLHLKKDO_01839 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_01840 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
PLHLKKDO_01841 1.77e-28 ykzE - - - - - - -
PLHLKKDO_01843 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
PLHLKKDO_01844 2.29e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PLHLKKDO_01845 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
PLHLKKDO_01846 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
PLHLKKDO_01847 2.82e-213 rsgI - - S - - - Anti-sigma factor N-terminus
PLHLKKDO_01848 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLHLKKDO_01849 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PLHLKKDO_01850 1.71e-143 ykoX - - S - - - membrane-associated protein
PLHLKKDO_01851 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
PLHLKKDO_01852 5.1e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PLHLKKDO_01853 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
PLHLKKDO_01854 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PLHLKKDO_01855 0.0 ykoS - - - - - - -
PLHLKKDO_01856 1.77e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
PLHLKKDO_01857 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
PLHLKKDO_01858 2.21e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
PLHLKKDO_01859 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
PLHLKKDO_01860 3.04e-36 ykoL - - - - - - -
PLHLKKDO_01861 1.63e-25 - - - - - - - -
PLHLKKDO_01862 1.49e-70 tnrA - - K - - - transcriptional
PLHLKKDO_01863 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
PLHLKKDO_01865 1.45e-08 - - - - - - - -
PLHLKKDO_01866 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
PLHLKKDO_01867 5.55e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
PLHLKKDO_01868 8.59e-307 ykoH - - T - - - Histidine kinase
PLHLKKDO_01869 5.02e-158 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_01870 3.07e-138 ykoF - - S - - - YKOF-related Family
PLHLKKDO_01871 8.05e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
PLHLKKDO_01872 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_01873 1.22e-171 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PLHLKKDO_01874 3.27e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PLHLKKDO_01875 4.27e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PLHLKKDO_01876 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PLHLKKDO_01877 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
PLHLKKDO_01878 1.65e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
PLHLKKDO_01879 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
PLHLKKDO_01880 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
PLHLKKDO_01881 1.32e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PLHLKKDO_01882 6.1e-255 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PLHLKKDO_01883 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PLHLKKDO_01884 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
PLHLKKDO_01885 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
PLHLKKDO_01886 1.71e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PLHLKKDO_01887 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
PLHLKKDO_01888 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
PLHLKKDO_01889 2.73e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PLHLKKDO_01890 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
PLHLKKDO_01891 1.78e-205 ykgA - - E - - - Amidinotransferase
PLHLKKDO_01892 3.29e-260 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
PLHLKKDO_01893 3.58e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PLHLKKDO_01894 2.17e-211 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PLHLKKDO_01895 1.62e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PLHLKKDO_01896 6.49e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
PLHLKKDO_01898 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PLHLKKDO_01899 1.35e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PLHLKKDO_01900 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PLHLKKDO_01901 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PLHLKKDO_01902 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
PLHLKKDO_01903 2.25e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
PLHLKKDO_01904 2.4e-282 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLHLKKDO_01906 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PLHLKKDO_01907 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PLHLKKDO_01908 2.31e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PLHLKKDO_01909 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
PLHLKKDO_01910 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
PLHLKKDO_01911 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
PLHLKKDO_01912 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
PLHLKKDO_01913 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
PLHLKKDO_01914 2.07e-205 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PLHLKKDO_01915 1.15e-52 xhlB - - S - - - SPP1 phage holin
PLHLKKDO_01916 2.21e-51 xhlA - - S - - - Haemolysin XhlA
PLHLKKDO_01917 1.39e-194 xepA - - - - - - -
PLHLKKDO_01918 2.68e-32 xkdX - - - - - - -
PLHLKKDO_01919 8.68e-74 xkdW - - S - - - XkdW protein
PLHLKKDO_01920 0.0 - - - - - - - -
PLHLKKDO_01921 6.29e-56 - - - - - - - -
PLHLKKDO_01922 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
PLHLKKDO_01923 1.79e-243 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PLHLKKDO_01924 7.71e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
PLHLKKDO_01925 1.76e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
PLHLKKDO_01926 2.31e-232 xkdQ - - G - - - NLP P60 protein
PLHLKKDO_01927 1.77e-158 xkdP - - S - - - Lysin motif
PLHLKKDO_01928 0.0 xkdO - - L - - - Transglycosylase SLT domain
PLHLKKDO_01929 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
PLHLKKDO_01930 6.01e-99 xkdM - - S - - - Phage tail tube protein
PLHLKKDO_01931 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
PLHLKKDO_01932 2.87e-101 xkdJ - - - - - - -
PLHLKKDO_01933 2.78e-113 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
PLHLKKDO_01934 1.75e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
PLHLKKDO_01935 4.68e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
PLHLKKDO_01936 3.91e-217 xkdG - - S - - - Phage capsid family
PLHLKKDO_01937 1.99e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
PLHLKKDO_01938 0.0 yqbA - - S - - - portal protein
PLHLKKDO_01939 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
PLHLKKDO_01940 7.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
PLHLKKDO_01941 9.88e-111 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PLHLKKDO_01945 1.02e-150 xkdC - - L - - - Bacterial dnaA protein
PLHLKKDO_01946 3.07e-202 xkdB - - K - - - sequence-specific DNA binding
PLHLKKDO_01948 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
PLHLKKDO_01949 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
PLHLKKDO_01950 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
PLHLKKDO_01951 5.99e-143 yjqB - - S - - - Pfam:DUF867
PLHLKKDO_01952 2.24e-79 yjqA - - S - - - Bacterial PH domain
PLHLKKDO_01953 1.37e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PLHLKKDO_01954 1.79e-55 - - - S - - - YCII-related domain
PLHLKKDO_01956 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PLHLKKDO_01957 1.18e-311 VCP - - O - - - AAA domain (dynein-related subfamily)
PLHLKKDO_01958 2.71e-103 yjoA - - S - - - DinB family
PLHLKKDO_01959 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
PLHLKKDO_01960 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
PLHLKKDO_01961 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
PLHLKKDO_01962 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
PLHLKKDO_01963 3.76e-287 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
PLHLKKDO_01964 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_01965 1.37e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
PLHLKKDO_01966 9.24e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
PLHLKKDO_01967 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
PLHLKKDO_01968 4.34e-314 - - - G ko:K03292 - ko00000 symporter YjmB
PLHLKKDO_01969 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
PLHLKKDO_01970 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PLHLKKDO_01971 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
PLHLKKDO_01972 2.36e-116 yjlB - - S - - - Cupin domain
PLHLKKDO_01973 7.35e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
PLHLKKDO_01974 1.27e-171 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PLHLKKDO_01975 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
PLHLKKDO_01976 1.23e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PLHLKKDO_01977 1.11e-41 - - - - - - - -
PLHLKKDO_01978 2.8e-276 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PLHLKKDO_01979 7.52e-283 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PLHLKKDO_01981 2.06e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
PLHLKKDO_01983 9.24e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
PLHLKKDO_01984 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
PLHLKKDO_01985 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
PLHLKKDO_01986 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
PLHLKKDO_01987 1.36e-211 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
PLHLKKDO_01988 1.13e-29 yjfB - - S - - - Putative motility protein
PLHLKKDO_01989 8.68e-106 - - - S - - - Protein of unknown function (DUF2690)
PLHLKKDO_01990 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
PLHLKKDO_01992 2.16e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PLHLKKDO_01993 1.49e-64 yjdJ - - S - - - Domain of unknown function (DUF4306)
PLHLKKDO_01994 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
PLHLKKDO_01995 1.12e-101 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PLHLKKDO_01997 5.12e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PLHLKKDO_01998 5.1e-73 yjdF3 - - S - - - Protein of unknown function (DUF2992)
PLHLKKDO_01999 5.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PLHLKKDO_02000 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_02001 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
PLHLKKDO_02002 0.000759 - - - - - - - -
PLHLKKDO_02003 8.05e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
PLHLKKDO_02004 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
PLHLKKDO_02005 2.49e-07 - - - - - - - -
PLHLKKDO_02006 3.94e-26 - - - - - - - -
PLHLKKDO_02007 1.92e-47 - - - - - - - -
PLHLKKDO_02010 5.44e-273 - - - S - - - Bacterial EndoU nuclease
PLHLKKDO_02011 6.99e-65 - - - - - - - -
PLHLKKDO_02013 2.58e-274 yjcL - - S - - - Protein of unknown function (DUF819)
PLHLKKDO_02014 1.62e-124 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
PLHLKKDO_02015 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PLHLKKDO_02016 4.65e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PLHLKKDO_02017 9.45e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
PLHLKKDO_02018 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
PLHLKKDO_02019 9.05e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PLHLKKDO_02020 6.31e-51 - - - - - - - -
PLHLKKDO_02021 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PLHLKKDO_02022 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
PLHLKKDO_02025 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
PLHLKKDO_02026 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
PLHLKKDO_02027 9.3e-32 cotW - - - ko:K06341 - ko00000 -
PLHLKKDO_02028 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
PLHLKKDO_02029 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
PLHLKKDO_02030 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
PLHLKKDO_02031 2.32e-107 yjbX - - S - - - Spore coat protein
PLHLKKDO_02032 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
PLHLKKDO_02033 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PLHLKKDO_02034 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PLHLKKDO_02035 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PLHLKKDO_02036 5.35e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
PLHLKKDO_02037 1.33e-276 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
PLHLKKDO_02038 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
PLHLKKDO_02039 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PLHLKKDO_02040 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PLHLKKDO_02041 5.47e-179 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PLHLKKDO_02042 4.28e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PLHLKKDO_02043 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PLHLKKDO_02044 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
PLHLKKDO_02045 3.1e-80 yjbL - - S - - - Belongs to the UPF0738 family
PLHLKKDO_02046 2.98e-129 yjbK - - S - - - protein conserved in bacteria
PLHLKKDO_02047 3.98e-126 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PLHLKKDO_02048 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
PLHLKKDO_02049 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PLHLKKDO_02051 2.68e-28 - - - - - - - -
PLHLKKDO_02052 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
PLHLKKDO_02053 9.9e-279 coiA - - S ko:K06198 - ko00000 Competence protein
PLHLKKDO_02054 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PLHLKKDO_02055 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
PLHLKKDO_02056 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PLHLKKDO_02057 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PLHLKKDO_02058 5.8e-261 yjbB - - EGP - - - Major Facilitator Superfamily
PLHLKKDO_02059 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PLHLKKDO_02060 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PLHLKKDO_02061 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PLHLKKDO_02062 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PLHLKKDO_02063 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PLHLKKDO_02064 7.18e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
PLHLKKDO_02065 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
PLHLKKDO_02066 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PLHLKKDO_02067 2.98e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PLHLKKDO_02068 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
PLHLKKDO_02069 3.43e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PLHLKKDO_02070 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PLHLKKDO_02071 9.48e-193 yjaZ - - O - - - Zn-dependent protease
PLHLKKDO_02072 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PLHLKKDO_02073 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PLHLKKDO_02074 2.67e-38 yjzB - - - - - - -
PLHLKKDO_02075 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
PLHLKKDO_02076 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
PLHLKKDO_02077 5.41e-134 yjaV - - - - - - -
PLHLKKDO_02078 4.88e-182 yjaU - - I - - - carboxylic ester hydrolase activity
PLHLKKDO_02079 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
PLHLKKDO_02080 2.51e-39 yjzC - - S - - - YjzC-like protein
PLHLKKDO_02081 1.05e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PLHLKKDO_02082 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
PLHLKKDO_02083 2.71e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PLHLKKDO_02084 7.69e-275 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
PLHLKKDO_02085 7.35e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
PLHLKKDO_02086 1.74e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PLHLKKDO_02087 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PLHLKKDO_02088 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
PLHLKKDO_02089 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
PLHLKKDO_02090 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
PLHLKKDO_02091 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
PLHLKKDO_02092 8.38e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PLHLKKDO_02093 2.16e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PLHLKKDO_02094 1.92e-08 - - - - - - - -
PLHLKKDO_02095 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
PLHLKKDO_02096 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
PLHLKKDO_02097 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PLHLKKDO_02098 9.13e-202 yitS - - S - - - protein conserved in bacteria
PLHLKKDO_02099 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
PLHLKKDO_02100 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
PLHLKKDO_02101 5.24e-121 - - - - - - - -
PLHLKKDO_02102 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
PLHLKKDO_02103 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
PLHLKKDO_02104 2.02e-218 - - - - - - - -
PLHLKKDO_02105 4.16e-122 - - - - - - - -
PLHLKKDO_02106 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
PLHLKKDO_02107 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
PLHLKKDO_02108 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PLHLKKDO_02109 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
PLHLKKDO_02110 2.23e-197 yitH - - K - - - Acetyltransferase (GNAT) domain
PLHLKKDO_02111 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_02112 2.5e-282 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PLHLKKDO_02113 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PLHLKKDO_02114 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
PLHLKKDO_02115 1.38e-155 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
PLHLKKDO_02116 3.87e-184 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
PLHLKKDO_02117 2.55e-291 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
PLHLKKDO_02118 1.17e-144 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
PLHLKKDO_02119 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PLHLKKDO_02120 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
PLHLKKDO_02121 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PLHLKKDO_02122 2.08e-128 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
PLHLKKDO_02123 2.34e-118 yisT - - S - - - DinB family
PLHLKKDO_02124 7.35e-249 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
PLHLKKDO_02125 4.32e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PLHLKKDO_02126 1.41e-207 yisR - - K - - - Transcriptional regulator
PLHLKKDO_02127 4.13e-310 yisQ - - V - - - Mate efflux family protein
PLHLKKDO_02128 3.24e-191 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
PLHLKKDO_02129 3.6e-113 yizA - - S - - - Damage-inducible protein DinB
PLHLKKDO_02130 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PLHLKKDO_02131 9.03e-133 yisN - - S - - - Protein of unknown function (DUF2777)
PLHLKKDO_02132 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PLHLKKDO_02133 2.05e-74 yisL - - S - - - UPF0344 protein
PLHLKKDO_02134 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PLHLKKDO_02135 7.04e-218 cotH - - M ko:K06330 - ko00000 Spore Coat
PLHLKKDO_02136 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
PLHLKKDO_02137 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
PLHLKKDO_02138 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
PLHLKKDO_02139 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
PLHLKKDO_02140 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
PLHLKKDO_02141 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
PLHLKKDO_02142 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
PLHLKKDO_02143 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
PLHLKKDO_02144 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
PLHLKKDO_02145 8.08e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PLHLKKDO_02146 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
PLHLKKDO_02147 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
PLHLKKDO_02148 9.3e-102 yhjR - - S - - - Rubrerythrin
PLHLKKDO_02149 2.51e-68 yhjQ - - C - - - COG1145 Ferredoxin
PLHLKKDO_02150 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
PLHLKKDO_02151 6.73e-268 - - - EGP - - - Transmembrane secretion effector
PLHLKKDO_02152 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
PLHLKKDO_02153 2.52e-238 yhjM - - K - - - Transcriptional regulator
PLHLKKDO_02154 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
PLHLKKDO_02155 1.52e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
PLHLKKDO_02156 1.14e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
PLHLKKDO_02157 5.18e-272 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
PLHLKKDO_02158 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
PLHLKKDO_02159 0.0 yhjG - - CH - - - FAD binding domain
PLHLKKDO_02160 5.12e-117 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PLHLKKDO_02161 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
PLHLKKDO_02162 2.12e-77 yhjD - - - - - - -
PLHLKKDO_02163 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
PLHLKKDO_02164 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLHLKKDO_02165 2.04e-56 yhjA - - S - - - Excalibur calcium-binding domain
PLHLKKDO_02166 1.48e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PLHLKKDO_02167 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
PLHLKKDO_02168 9.84e-45 yhzC - - S - - - IDEAL
PLHLKKDO_02169 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_02170 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
PLHLKKDO_02171 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
PLHLKKDO_02172 8.51e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
PLHLKKDO_02173 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PLHLKKDO_02174 3e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PLHLKKDO_02175 3.93e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
PLHLKKDO_02176 4.59e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PLHLKKDO_02177 3.98e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
PLHLKKDO_02178 4.21e-100 - - - K - - - acetyltransferase
PLHLKKDO_02179 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PLHLKKDO_02180 5.34e-305 yhfN - - O - - - Peptidase M48
PLHLKKDO_02181 2.78e-85 yhfM - - - - - - -
PLHLKKDO_02182 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PLHLKKDO_02183 2.48e-142 yhfK - - GM - - - NmrA-like family
PLHLKKDO_02184 3.34e-244 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
PLHLKKDO_02185 3.43e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PLHLKKDO_02186 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PLHLKKDO_02187 6.22e-93 - - - S - - - ASCH
PLHLKKDO_02188 2.68e-253 yhfE - - G - - - peptidase M42
PLHLKKDO_02189 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
PLHLKKDO_02190 3.43e-234 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PLHLKKDO_02191 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
PLHLKKDO_02192 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_02193 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PLHLKKDO_02194 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
PLHLKKDO_02195 1.06e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PLHLKKDO_02196 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PLHLKKDO_02197 5.35e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
PLHLKKDO_02198 2.31e-24 - - - C - - - Rubrerythrin
PLHLKKDO_02199 6.63e-313 yhfA - - C - - - membrane
PLHLKKDO_02200 2.19e-291 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PLHLKKDO_02201 2.04e-161 ecsC - - S - - - EcsC protein family
PLHLKKDO_02202 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
PLHLKKDO_02203 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
PLHLKKDO_02204 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PLHLKKDO_02205 5.91e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PLHLKKDO_02206 3.66e-103 trpP - - S - - - Tryptophan transporter TrpP
PLHLKKDO_02207 9.66e-30 - - - - - - - -
PLHLKKDO_02208 1.74e-54 yhaH - - S - - - YtxH-like protein
PLHLKKDO_02209 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
PLHLKKDO_02210 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
PLHLKKDO_02211 5.71e-116 yhaK - - S - - - Putative zincin peptidase
PLHLKKDO_02212 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PLHLKKDO_02213 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
PLHLKKDO_02214 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
PLHLKKDO_02215 0.0 yhaN - - L - - - AAA domain
PLHLKKDO_02216 4.68e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
PLHLKKDO_02217 1.04e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
PLHLKKDO_02218 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_02219 9.36e-36 - - - S - - - YhzD-like protein
PLHLKKDO_02220 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
PLHLKKDO_02222 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PLHLKKDO_02223 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
PLHLKKDO_02224 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
PLHLKKDO_02225 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
PLHLKKDO_02226 1.24e-259 yhaZ - - L - - - DNA alkylation repair enzyme
PLHLKKDO_02227 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
PLHLKKDO_02228 9.78e-258 yheB - - S - - - Belongs to the UPF0754 family
PLHLKKDO_02229 9.67e-276 yheC - - HJ - - - YheC/D like ATP-grasp
PLHLKKDO_02230 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
PLHLKKDO_02231 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
PLHLKKDO_02232 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
PLHLKKDO_02233 3.86e-142 yheG - - GM - - - NAD(P)H-binding
PLHLKKDO_02234 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PLHLKKDO_02235 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PLHLKKDO_02236 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
PLHLKKDO_02237 3.61e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PLHLKKDO_02238 1.5e-195 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PLHLKKDO_02239 1.63e-199 nodB1 - - G - - - deacetylase
PLHLKKDO_02240 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PLHLKKDO_02241 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
PLHLKKDO_02242 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
PLHLKKDO_02243 3.68e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PLHLKKDO_02244 1.67e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PLHLKKDO_02245 5.44e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PLHLKKDO_02246 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
PLHLKKDO_02247 4.19e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PLHLKKDO_02248 4.37e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
PLHLKKDO_02249 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PLHLKKDO_02250 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PLHLKKDO_02251 6.74e-244 yhdN - - C - - - Aldo keto reductase
PLHLKKDO_02252 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_02253 3.54e-257 yhdL - - S - - - Sigma factor regulator N-terminal
PLHLKKDO_02254 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
PLHLKKDO_02255 7.13e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PLHLKKDO_02256 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PLHLKKDO_02257 1.01e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PLHLKKDO_02258 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
PLHLKKDO_02259 5.51e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_02260 3.72e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PLHLKKDO_02261 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_02262 9.79e-202 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PLHLKKDO_02263 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PLHLKKDO_02264 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
PLHLKKDO_02265 1.51e-306 ygxB - - M - - - Conserved TM helix
PLHLKKDO_02266 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
PLHLKKDO_02267 3.25e-273 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PLHLKKDO_02268 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
PLHLKKDO_02269 1.65e-51 yhdB - - S - - - YhdB-like protein
PLHLKKDO_02270 1.63e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
PLHLKKDO_02271 3.15e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PLHLKKDO_02272 1.8e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_02273 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
PLHLKKDO_02274 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PLHLKKDO_02275 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PLHLKKDO_02276 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PLHLKKDO_02277 5.67e-128 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PLHLKKDO_02278 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PLHLKKDO_02279 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PLHLKKDO_02280 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
PLHLKKDO_02281 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
PLHLKKDO_02282 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
PLHLKKDO_02283 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PLHLKKDO_02284 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
PLHLKKDO_02285 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PLHLKKDO_02286 9.74e-146 yhcQ - - M - - - Spore coat protein
PLHLKKDO_02287 7.66e-201 yhcP - - - - - - -
PLHLKKDO_02288 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PLHLKKDO_02289 1.96e-71 yhcM - - - - - - -
PLHLKKDO_02290 3.72e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PLHLKKDO_02291 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
PLHLKKDO_02292 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PLHLKKDO_02293 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
PLHLKKDO_02294 1.4e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PLHLKKDO_02295 4.37e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_02296 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_02297 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_02298 2.92e-69 - - - - - - - -
PLHLKKDO_02299 3.95e-59 yhcC - - - - - - -
PLHLKKDO_02300 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
PLHLKKDO_02301 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
PLHLKKDO_02302 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
PLHLKKDO_02303 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
PLHLKKDO_02304 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
PLHLKKDO_02305 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
PLHLKKDO_02306 4.06e-103 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PLHLKKDO_02307 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PLHLKKDO_02308 1.38e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
PLHLKKDO_02309 5.37e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PLHLKKDO_02310 2.77e-225 yhbB - - S - - - Putative amidase domain
PLHLKKDO_02311 2.07e-284 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PLHLKKDO_02312 1.92e-147 yhzB - - S - - - B3/4 domain
PLHLKKDO_02314 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_02315 9.35e-101 ygaO - - - - - - -
PLHLKKDO_02316 4.64e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PLHLKKDO_02318 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
PLHLKKDO_02319 2.39e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PLHLKKDO_02320 1.7e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
PLHLKKDO_02321 7.1e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PLHLKKDO_02322 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PLHLKKDO_02324 0.0 ygaK - - C - - - Berberine and berberine like
PLHLKKDO_02325 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PLHLKKDO_02326 4.02e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
PLHLKKDO_02327 3.88e-37 - - - - - - - -
PLHLKKDO_02328 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
PLHLKKDO_02333 7.22e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
PLHLKKDO_02334 9.48e-120 - - - M - - - FR47-like protein
PLHLKKDO_02335 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
PLHLKKDO_02336 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
PLHLKKDO_02337 1.95e-109 yuaE - - S - - - DinB superfamily
PLHLKKDO_02338 3.5e-138 yuaD - - - - - - -
PLHLKKDO_02339 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
PLHLKKDO_02340 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PLHLKKDO_02341 1.14e-119 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
PLHLKKDO_02342 5.83e-118 yuaB - - - - - - -
PLHLKKDO_02343 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PLHLKKDO_02344 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
PLHLKKDO_02345 3.31e-52 yubF - - S - - - yiaA/B two helix domain
PLHLKKDO_02346 3.6e-194 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PLHLKKDO_02347 0.0 yubD - - P - - - Major Facilitator Superfamily
PLHLKKDO_02348 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
PLHLKKDO_02350 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PLHLKKDO_02351 3.12e-255 yubA - - S - - - transporter activity
PLHLKKDO_02352 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PLHLKKDO_02353 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
PLHLKKDO_02354 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
PLHLKKDO_02355 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PLHLKKDO_02356 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PLHLKKDO_02357 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
PLHLKKDO_02358 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PLHLKKDO_02359 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PLHLKKDO_02360 4.08e-291 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PLHLKKDO_02361 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PLHLKKDO_02362 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
PLHLKKDO_02363 1.44e-47 - - - - - - - -
PLHLKKDO_02364 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
PLHLKKDO_02365 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PLHLKKDO_02366 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PLHLKKDO_02367 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
PLHLKKDO_02368 2.24e-50 - - - - - - - -
PLHLKKDO_02369 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
PLHLKKDO_02370 2.06e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
PLHLKKDO_02371 1.72e-94 yugN - - S - - - YugN-like family
PLHLKKDO_02373 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PLHLKKDO_02374 4.38e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
PLHLKKDO_02375 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
PLHLKKDO_02376 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
PLHLKKDO_02377 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PLHLKKDO_02378 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
PLHLKKDO_02379 6.74e-112 alaR - - K - - - Transcriptional regulator
PLHLKKDO_02380 1.64e-199 yugF - - I - - - Hydrolase
PLHLKKDO_02381 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
PLHLKKDO_02382 1.16e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PLHLKKDO_02383 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_02384 1.19e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
PLHLKKDO_02385 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
PLHLKKDO_02387 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
PLHLKKDO_02388 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
PLHLKKDO_02389 3.31e-98 yuxK - - S - - - protein conserved in bacteria
PLHLKKDO_02390 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
PLHLKKDO_02391 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PLHLKKDO_02392 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PLHLKKDO_02393 1.28e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
PLHLKKDO_02394 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_02395 1.83e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PLHLKKDO_02396 1.21e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PLHLKKDO_02397 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
PLHLKKDO_02398 3e-23 - - - - - - - -
PLHLKKDO_02399 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PLHLKKDO_02400 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PLHLKKDO_02401 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PLHLKKDO_02402 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PLHLKKDO_02403 2.47e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PLHLKKDO_02404 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PLHLKKDO_02405 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
PLHLKKDO_02406 2.24e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
PLHLKKDO_02407 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PLHLKKDO_02408 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_02410 8.19e-169 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
PLHLKKDO_02411 6.29e-10 - - - S - - - DegQ (SacQ) family
PLHLKKDO_02412 8.73e-09 yuzC - - - - - - -
PLHLKKDO_02413 2.4e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
PLHLKKDO_02414 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PLHLKKDO_02415 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
PLHLKKDO_02416 1.48e-85 - - - S - - - Protein of unknown function (DUF1694)
PLHLKKDO_02417 1.63e-52 yueH - - S - - - YueH-like protein
PLHLKKDO_02418 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
PLHLKKDO_02419 2.24e-243 yueF - - S - - - transporter activity
PLHLKKDO_02420 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
PLHLKKDO_02421 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
PLHLKKDO_02422 6.39e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
PLHLKKDO_02423 3.53e-170 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_02424 7.25e-96 yueC - - S - - - Family of unknown function (DUF5383)
PLHLKKDO_02425 0.0 yueB - - S - - - type VII secretion protein EsaA
PLHLKKDO_02426 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PLHLKKDO_02427 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
PLHLKKDO_02428 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
PLHLKKDO_02429 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
PLHLKKDO_02430 1.03e-292 yukF - - QT - - - Transcriptional regulator
PLHLKKDO_02431 2.33e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
PLHLKKDO_02432 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
PLHLKKDO_02433 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
PLHLKKDO_02434 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_02435 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
PLHLKKDO_02436 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
PLHLKKDO_02437 8.56e-290 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PLHLKKDO_02438 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_02439 8.94e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
PLHLKKDO_02440 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
PLHLKKDO_02441 9.71e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
PLHLKKDO_02442 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
PLHLKKDO_02443 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PLHLKKDO_02444 7.09e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
PLHLKKDO_02445 3.14e-149 yuiC - - S - - - protein conserved in bacteria
PLHLKKDO_02446 1.14e-45 yuiB - - S - - - Putative membrane protein
PLHLKKDO_02447 8.4e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PLHLKKDO_02448 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
PLHLKKDO_02450 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PLHLKKDO_02451 5.51e-147 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
PLHLKKDO_02452 1.39e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PLHLKKDO_02453 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
PLHLKKDO_02454 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PLHLKKDO_02455 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PLHLKKDO_02456 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
PLHLKKDO_02457 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PLHLKKDO_02458 1.1e-73 yuzD - - S - - - protein conserved in bacteria
PLHLKKDO_02459 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
PLHLKKDO_02460 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
PLHLKKDO_02461 1.04e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PLHLKKDO_02462 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PLHLKKDO_02463 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
PLHLKKDO_02464 4.45e-253 yutH - - S - - - Spore coat protein
PLHLKKDO_02465 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
PLHLKKDO_02466 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PLHLKKDO_02467 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
PLHLKKDO_02468 3.2e-63 yutD - - S - - - protein conserved in bacteria
PLHLKKDO_02469 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PLHLKKDO_02470 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PLHLKKDO_02471 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
PLHLKKDO_02472 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
PLHLKKDO_02473 1.39e-64 yunC - - S - - - Domain of unknown function (DUF1805)
PLHLKKDO_02474 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PLHLKKDO_02475 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
PLHLKKDO_02476 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
PLHLKKDO_02477 1.07e-79 yunG - - - - - - -
PLHLKKDO_02478 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PLHLKKDO_02479 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
PLHLKKDO_02480 3.65e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
PLHLKKDO_02481 7.82e-284 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
PLHLKKDO_02482 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
PLHLKKDO_02483 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
PLHLKKDO_02484 2.95e-123 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PLHLKKDO_02485 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PLHLKKDO_02486 8.04e-193 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PLHLKKDO_02487 3.58e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
PLHLKKDO_02488 4.33e-235 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PLHLKKDO_02490 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PLHLKKDO_02491 1.99e-302 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PLHLKKDO_02492 7.32e-215 bsn - - L - - - Ribonuclease
PLHLKKDO_02493 6.95e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PLHLKKDO_02494 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
PLHLKKDO_02495 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
PLHLKKDO_02496 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PLHLKKDO_02497 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PLHLKKDO_02498 9.59e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
PLHLKKDO_02499 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PLHLKKDO_02500 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
PLHLKKDO_02501 5.31e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
PLHLKKDO_02503 3.35e-56 - - - - - - - -
PLHLKKDO_02504 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
PLHLKKDO_02505 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
PLHLKKDO_02506 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PLHLKKDO_02507 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
PLHLKKDO_02508 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PLHLKKDO_02509 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PLHLKKDO_02510 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
PLHLKKDO_02511 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
PLHLKKDO_02512 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PLHLKKDO_02513 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
PLHLKKDO_02514 2e-73 yusE - - CO - - - Thioredoxin
PLHLKKDO_02515 2.66e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
PLHLKKDO_02516 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
PLHLKKDO_02517 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PLHLKKDO_02518 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
PLHLKKDO_02519 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PLHLKKDO_02520 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
PLHLKKDO_02521 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
PLHLKKDO_02522 1.11e-13 - - - S - - - YuzL-like protein
PLHLKKDO_02523 6.98e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PLHLKKDO_02524 4.51e-54 - - - - - - - -
PLHLKKDO_02525 8.66e-70 yusN - - M - - - Coat F domain
PLHLKKDO_02526 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
PLHLKKDO_02527 0.0 yusP - - P - - - Major facilitator superfamily
PLHLKKDO_02528 1.7e-84 yusQ - - S - - - Tautomerase enzyme
PLHLKKDO_02529 8.6e-139 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_02530 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
PLHLKKDO_02531 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
PLHLKKDO_02532 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PLHLKKDO_02533 3.48e-88 - - - S - - - YusW-like protein
PLHLKKDO_02534 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
PLHLKKDO_02535 1.1e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_02536 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
PLHLKKDO_02537 5.56e-305 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLHLKKDO_02538 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_02539 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_02540 1.25e-203 yuxN - - K - - - Transcriptional regulator
PLHLKKDO_02541 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PLHLKKDO_02542 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
PLHLKKDO_02543 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PLHLKKDO_02544 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PLHLKKDO_02545 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
PLHLKKDO_02546 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PLHLKKDO_02547 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_02548 1.27e-162 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
PLHLKKDO_02549 4.23e-174 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
PLHLKKDO_02550 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PLHLKKDO_02551 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
PLHLKKDO_02552 4.58e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_02553 1.59e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
PLHLKKDO_02554 1.74e-307 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PLHLKKDO_02555 4.47e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_02556 3.48e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PLHLKKDO_02557 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_02558 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
PLHLKKDO_02559 0.0 yvrG - - T - - - Histidine kinase
PLHLKKDO_02560 2.08e-169 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_02561 5.07e-32 - - - - - - - -
PLHLKKDO_02562 4.06e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
PLHLKKDO_02563 3.46e-26 - - - S - - - YvrJ protein family
PLHLKKDO_02564 1.08e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PLHLKKDO_02565 1.64e-84 yvrL - - S - - - Regulatory protein YrvL
PLHLKKDO_02566 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PLHLKKDO_02567 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_02568 6.94e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
PLHLKKDO_02569 9.78e-190 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PLHLKKDO_02570 9.64e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_02571 3.47e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_02572 1.09e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PLHLKKDO_02573 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
PLHLKKDO_02574 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
PLHLKKDO_02575 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
PLHLKKDO_02576 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
PLHLKKDO_02577 4.21e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
PLHLKKDO_02578 4.96e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
PLHLKKDO_02579 1.43e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
PLHLKKDO_02580 6.19e-201 yvgN - - S - - - reductase
PLHLKKDO_02581 7.97e-113 yvgO - - - - - - -
PLHLKKDO_02582 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
PLHLKKDO_02583 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PLHLKKDO_02584 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PLHLKKDO_02585 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PLHLKKDO_02586 3.88e-140 yvgT - - S - - - membrane
PLHLKKDO_02587 1.15e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
PLHLKKDO_02588 3.45e-137 bdbD - - O - - - Thioredoxin
PLHLKKDO_02589 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PLHLKKDO_02590 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PLHLKKDO_02591 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
PLHLKKDO_02592 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
PLHLKKDO_02593 2.42e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PLHLKKDO_02594 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PLHLKKDO_02595 0.0 - - - S - - - Fusaric acid resistance protein-like
PLHLKKDO_02596 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
PLHLKKDO_02597 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
PLHLKKDO_02598 1.51e-123 - - - K - - - Bacterial regulatory proteins, tetR family
PLHLKKDO_02599 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_02601 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PLHLKKDO_02602 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PLHLKKDO_02603 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
PLHLKKDO_02604 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
PLHLKKDO_02605 2.73e-192 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
PLHLKKDO_02606 3.44e-48 yvzC - - K - - - transcriptional
PLHLKKDO_02607 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
PLHLKKDO_02608 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PLHLKKDO_02609 3.85e-72 yvaP - - K - - - transcriptional
PLHLKKDO_02610 5.86e-59 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PLHLKKDO_02611 8.64e-235 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PLHLKKDO_02612 1.25e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PLHLKKDO_02613 3.33e-215 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PLHLKKDO_02614 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PLHLKKDO_02615 4.75e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PLHLKKDO_02616 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PLHLKKDO_02617 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PLHLKKDO_02618 5e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PLHLKKDO_02619 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PLHLKKDO_02620 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PLHLKKDO_02621 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PLHLKKDO_02622 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
PLHLKKDO_02623 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
PLHLKKDO_02624 1.61e-156 yvbI - - M - - - Membrane
PLHLKKDO_02625 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
PLHLKKDO_02626 6.87e-106 yvbK - - K - - - acetyltransferase
PLHLKKDO_02627 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PLHLKKDO_02628 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
PLHLKKDO_02629 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PLHLKKDO_02630 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
PLHLKKDO_02631 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PLHLKKDO_02632 9.84e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PLHLKKDO_02633 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PLHLKKDO_02634 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
PLHLKKDO_02635 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLHLKKDO_02636 4.9e-206 yvbU - - K - - - Transcriptional regulator
PLHLKKDO_02637 1.13e-197 yvbV - - EG - - - EamA-like transporter family
PLHLKKDO_02638 1.37e-304 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PLHLKKDO_02639 6.04e-249 - - - S - - - Glycosyl hydrolase
PLHLKKDO_02640 2.4e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PLHLKKDO_02641 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PLHLKKDO_02642 3.17e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PLHLKKDO_02643 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PLHLKKDO_02644 4.24e-249 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_02645 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PLHLKKDO_02646 6.37e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
PLHLKKDO_02647 4.2e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
PLHLKKDO_02648 2.93e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
PLHLKKDO_02649 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
PLHLKKDO_02650 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
PLHLKKDO_02651 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
PLHLKKDO_02652 1.24e-299 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
PLHLKKDO_02653 8.35e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
PLHLKKDO_02654 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_02655 1.18e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
PLHLKKDO_02656 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PLHLKKDO_02657 9.59e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PLHLKKDO_02658 5.69e-44 yvfG - - S - - - YvfG protein
PLHLKKDO_02659 2.95e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
PLHLKKDO_02660 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
PLHLKKDO_02661 1.17e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PLHLKKDO_02662 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PLHLKKDO_02663 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PLHLKKDO_02664 1.03e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PLHLKKDO_02665 9.86e-262 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
PLHLKKDO_02666 1e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PLHLKKDO_02667 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
PLHLKKDO_02668 6.88e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PLHLKKDO_02669 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
PLHLKKDO_02670 2.95e-286 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
PLHLKKDO_02671 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PLHLKKDO_02672 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PLHLKKDO_02673 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
PLHLKKDO_02674 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
PLHLKKDO_02675 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
PLHLKKDO_02677 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
PLHLKKDO_02678 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
PLHLKKDO_02679 2.06e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PLHLKKDO_02680 2.33e-71 pbpE - - V - - - Beta-lactamase
PLHLKKDO_02681 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
PLHLKKDO_02682 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PLHLKKDO_02683 0.0 ybeC - - E - - - amino acid
PLHLKKDO_02684 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
PLHLKKDO_02685 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PLHLKKDO_02686 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
PLHLKKDO_02687 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
PLHLKKDO_02688 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
PLHLKKDO_02689 9.45e-234 - - - S - - - Patatin-like phospholipase
PLHLKKDO_02691 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PLHLKKDO_02692 1.22e-152 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PLHLKKDO_02693 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PLHLKKDO_02694 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
PLHLKKDO_02695 9.74e-198 malA - - S - - - Protein of unknown function (DUF1189)
PLHLKKDO_02696 2.79e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
PLHLKKDO_02697 2.48e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
PLHLKKDO_02698 3.44e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
PLHLKKDO_02699 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
PLHLKKDO_02700 1.32e-222 yvdE - - K - - - Transcriptional regulator
PLHLKKDO_02701 5.37e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
PLHLKKDO_02702 4.54e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
PLHLKKDO_02703 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PLHLKKDO_02704 1.25e-135 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PLHLKKDO_02705 1.9e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PLHLKKDO_02706 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
PLHLKKDO_02707 2.58e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_02708 1.38e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
PLHLKKDO_02709 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_02710 7.95e-45 - - - - - - - -
PLHLKKDO_02711 3.81e-181 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
PLHLKKDO_02712 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
PLHLKKDO_02713 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PLHLKKDO_02714 2.73e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
PLHLKKDO_02715 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PLHLKKDO_02716 5.65e-116 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PLHLKKDO_02717 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PLHLKKDO_02718 3.79e-185 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
PLHLKKDO_02719 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
PLHLKKDO_02720 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
PLHLKKDO_02722 1.84e-314 - - - - - - - -
PLHLKKDO_02723 3.94e-103 - - - - - - - -
PLHLKKDO_02724 3.05e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
PLHLKKDO_02725 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PLHLKKDO_02726 5.38e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PLHLKKDO_02727 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PLHLKKDO_02728 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
PLHLKKDO_02729 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PLHLKKDO_02730 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PLHLKKDO_02731 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PLHLKKDO_02732 5.03e-178 yvpB - - NU - - - protein conserved in bacteria
PLHLKKDO_02733 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
PLHLKKDO_02734 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PLHLKKDO_02735 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PLHLKKDO_02736 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
PLHLKKDO_02737 2.15e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PLHLKKDO_02738 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PLHLKKDO_02739 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PLHLKKDO_02740 3.51e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PLHLKKDO_02741 8.67e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
PLHLKKDO_02742 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
PLHLKKDO_02743 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
PLHLKKDO_02744 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
PLHLKKDO_02745 9.59e-220 yvlB - - S - - - Putative adhesin
PLHLKKDO_02746 8.09e-65 yvlA - - - - - - -
PLHLKKDO_02747 2.25e-45 yvkN - - - - - - -
PLHLKKDO_02748 4.93e-64 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PLHLKKDO_02749 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PLHLKKDO_02750 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PLHLKKDO_02751 2.54e-42 csbA - - S - - - protein conserved in bacteria
PLHLKKDO_02752 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
PLHLKKDO_02753 4.09e-131 yvkB - - K - - - Transcriptional regulator
PLHLKKDO_02754 5.24e-296 yvkA - - P - - - -transporter
PLHLKKDO_02755 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLHLKKDO_02756 1.38e-73 swrA - - S - - - Swarming motility protein
PLHLKKDO_02757 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PLHLKKDO_02758 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PLHLKKDO_02759 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
PLHLKKDO_02760 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PLHLKKDO_02761 1.86e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PLHLKKDO_02762 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PLHLKKDO_02763 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PLHLKKDO_02764 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PLHLKKDO_02765 9.14e-88 - - - - - - - -
PLHLKKDO_02766 1.73e-08 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
PLHLKKDO_02767 2.1e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
PLHLKKDO_02768 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PLHLKKDO_02769 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
PLHLKKDO_02770 3.11e-143 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PLHLKKDO_02771 1.23e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PLHLKKDO_02772 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PLHLKKDO_02773 1.7e-92 yviE - - - - - - -
PLHLKKDO_02774 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
PLHLKKDO_02775 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
PLHLKKDO_02776 3.5e-102 yvyG - - NOU - - - FlgN protein
PLHLKKDO_02777 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
PLHLKKDO_02778 1.83e-96 yvyF - - S - - - flagellar protein
PLHLKKDO_02779 8.82e-160 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
PLHLKKDO_02780 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
PLHLKKDO_02781 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PLHLKKDO_02782 2.15e-199 degV - - S - - - protein conserved in bacteria
PLHLKKDO_02783 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PLHLKKDO_02784 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PLHLKKDO_02785 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
PLHLKKDO_02786 9.37e-224 yvhJ - - K - - - Transcriptional regulator
PLHLKKDO_02787 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PLHLKKDO_02788 4.13e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
PLHLKKDO_02789 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PLHLKKDO_02790 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
PLHLKKDO_02791 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
PLHLKKDO_02792 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PLHLKKDO_02793 1.34e-277 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
PLHLKKDO_02794 5.16e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PLHLKKDO_02795 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PLHLKKDO_02796 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PLHLKKDO_02797 0.0 lytB - - D - - - Stage II sporulation protein
PLHLKKDO_02798 3.26e-50 - - - - - - - -
PLHLKKDO_02799 1.13e-218 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PLHLKKDO_02800 1.1e-276 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PLHLKKDO_02801 2.53e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PLHLKKDO_02802 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PLHLKKDO_02803 1.69e-193 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
PLHLKKDO_02804 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PLHLKKDO_02805 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
PLHLKKDO_02806 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
PLHLKKDO_02807 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PLHLKKDO_02808 7.34e-271 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PLHLKKDO_02809 5.15e-49 - - - - - - - -
PLHLKKDO_02810 8.52e-217 - - - - - - - -
PLHLKKDO_02811 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PLHLKKDO_02812 9.14e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PLHLKKDO_02813 3.12e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
PLHLKKDO_02814 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PLHLKKDO_02815 1.95e-251 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
PLHLKKDO_02816 2.27e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PLHLKKDO_02817 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
PLHLKKDO_02818 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PLHLKKDO_02819 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PLHLKKDO_02820 2.29e-29 ywtC - - - - - - -
PLHLKKDO_02821 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PLHLKKDO_02822 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
PLHLKKDO_02823 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
PLHLKKDO_02824 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
PLHLKKDO_02825 7.52e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PLHLKKDO_02826 3.24e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PLHLKKDO_02827 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PLHLKKDO_02828 4.55e-201 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PLHLKKDO_02829 1.28e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
PLHLKKDO_02830 5.88e-121 batE - - T - - - Sh3 type 3 domain protein
PLHLKKDO_02831 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
PLHLKKDO_02832 3.57e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
PLHLKKDO_02833 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
PLHLKKDO_02834 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
PLHLKKDO_02835 3.36e-218 alsR - - K - - - LysR substrate binding domain
PLHLKKDO_02836 2.79e-280 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PLHLKKDO_02837 2.14e-162 ywrJ - - - - - - -
PLHLKKDO_02838 1.25e-179 cotB - - - ko:K06325 - ko00000 -
PLHLKKDO_02839 2.64e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
PLHLKKDO_02840 2.17e-16 - - - - - - - -
PLHLKKDO_02841 8.79e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PLHLKKDO_02842 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
PLHLKKDO_02843 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PLHLKKDO_02844 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PLHLKKDO_02845 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
PLHLKKDO_02846 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
PLHLKKDO_02848 5.23e-130 ywqN - - S - - - NAD(P)H-dependent
PLHLKKDO_02849 3.89e-208 - - - K - - - Transcriptional regulator
PLHLKKDO_02850 7.19e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
PLHLKKDO_02852 5.82e-302 ywqJ - - S - - - Pre-toxin TG
PLHLKKDO_02853 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
PLHLKKDO_02855 1.46e-196 ywqG - - S - - - Domain of unknown function (DUF1963)
PLHLKKDO_02856 2.21e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PLHLKKDO_02857 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
PLHLKKDO_02858 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PLHLKKDO_02859 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
PLHLKKDO_02860 3.6e-25 - - - - - - - -
PLHLKKDO_02861 0.0 ywqB - - S - - - SWIM zinc finger
PLHLKKDO_02862 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PLHLKKDO_02863 3.57e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PLHLKKDO_02864 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PLHLKKDO_02865 3.48e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
PLHLKKDO_02866 3.04e-87 ywpG - - - - - - -
PLHLKKDO_02867 8.81e-89 ywpF - - S - - - YwpF-like protein
PLHLKKDO_02868 4.46e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PLHLKKDO_02869 3.42e-188 ywpD - - T - - - Histidine kinase
PLHLKKDO_02870 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PLHLKKDO_02871 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PLHLKKDO_02872 1.05e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
PLHLKKDO_02873 3.37e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PLHLKKDO_02874 1.77e-172 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PLHLKKDO_02875 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
PLHLKKDO_02876 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
PLHLKKDO_02877 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
PLHLKKDO_02878 5.56e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_02879 2.79e-310 ywoF - - P - - - Right handed beta helix region
PLHLKKDO_02880 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
PLHLKKDO_02881 3.11e-306 ywoD - - EGP - - - Major facilitator superfamily
PLHLKKDO_02882 2.11e-133 yjgF - - Q - - - Isochorismatase family
PLHLKKDO_02883 4.84e-99 - - - - - - - -
PLHLKKDO_02884 3.22e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
PLHLKKDO_02885 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
PLHLKKDO_02886 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
PLHLKKDO_02887 4.31e-91 ywnJ - - S - - - VanZ like family
PLHLKKDO_02888 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PLHLKKDO_02889 1.49e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
PLHLKKDO_02890 4.64e-22 ywnC - - S - - - Family of unknown function (DUF5362)
PLHLKKDO_02891 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
PLHLKKDO_02892 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PLHLKKDO_02893 2.69e-181 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
PLHLKKDO_02894 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
PLHLKKDO_02895 2.56e-140 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
PLHLKKDO_02896 9.24e-85 ywnA - - K - - - Transcriptional regulator
PLHLKKDO_02897 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PLHLKKDO_02898 1.3e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
PLHLKKDO_02899 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
PLHLKKDO_02900 1.11e-21 csbD - - K - - - CsbD-like
PLHLKKDO_02901 1.59e-109 ywmF - - S - - - Peptidase M50
PLHLKKDO_02902 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PLHLKKDO_02903 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PLHLKKDO_02904 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PLHLKKDO_02906 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PLHLKKDO_02907 9e-156 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PLHLKKDO_02908 2.8e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
PLHLKKDO_02909 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PLHLKKDO_02910 1.81e-169 ywmB - - S - - - TATA-box binding
PLHLKKDO_02911 4.54e-45 ywzB - - S - - - membrane
PLHLKKDO_02912 8.36e-113 ywmA - - - - - - -
PLHLKKDO_02913 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PLHLKKDO_02914 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PLHLKKDO_02915 5.21e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PLHLKKDO_02916 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PLHLKKDO_02917 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PLHLKKDO_02918 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PLHLKKDO_02919 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PLHLKKDO_02920 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PLHLKKDO_02921 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
PLHLKKDO_02922 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PLHLKKDO_02923 1.25e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PLHLKKDO_02924 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
PLHLKKDO_02925 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
PLHLKKDO_02926 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PLHLKKDO_02927 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
PLHLKKDO_02928 3e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PLHLKKDO_02929 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
PLHLKKDO_02930 9.35e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
PLHLKKDO_02931 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PLHLKKDO_02933 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PLHLKKDO_02934 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PLHLKKDO_02935 9.41e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PLHLKKDO_02936 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PLHLKKDO_02937 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
PLHLKKDO_02938 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PLHLKKDO_02939 4.93e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
PLHLKKDO_02940 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
PLHLKKDO_02941 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PLHLKKDO_02942 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
PLHLKKDO_02943 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PLHLKKDO_02944 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PLHLKKDO_02945 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
PLHLKKDO_02946 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
PLHLKKDO_02947 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
PLHLKKDO_02948 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PLHLKKDO_02949 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PLHLKKDO_02950 1.42e-267 acdA - - I - - - acyl-CoA dehydrogenase
PLHLKKDO_02951 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
PLHLKKDO_02952 4.95e-289 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PLHLKKDO_02953 1.99e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PLHLKKDO_02954 1.32e-57 ywjC - - - - - - -
PLHLKKDO_02955 3.71e-122 ywjB - - H - - - RibD C-terminal domain
PLHLKKDO_02956 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
PLHLKKDO_02957 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PLHLKKDO_02958 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
PLHLKKDO_02959 2.28e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
PLHLKKDO_02960 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
PLHLKKDO_02961 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PLHLKKDO_02962 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
PLHLKKDO_02963 1.84e-179 ywiC - - S - - - YwiC-like protein
PLHLKKDO_02964 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
PLHLKKDO_02965 3.39e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
PLHLKKDO_02966 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
PLHLKKDO_02967 4.64e-96 ywiB - - S - - - protein conserved in bacteria
PLHLKKDO_02968 3.71e-12 - - - S - - - Bacteriocin subtilosin A
PLHLKKDO_02969 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
PLHLKKDO_02971 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PLHLKKDO_02972 1.07e-300 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
PLHLKKDO_02973 7.55e-280 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
PLHLKKDO_02974 0.0 - - - L - - - Peptidase, M16
PLHLKKDO_02976 0.0 ywhL - - CO - - - amine dehydrogenase activity
PLHLKKDO_02977 4.56e-289 ywhK - - CO - - - amine dehydrogenase activity
PLHLKKDO_02978 1.64e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PLHLKKDO_02982 1.3e-10 - - - - - - - -
PLHLKKDO_02985 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PLHLKKDO_02987 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PLHLKKDO_02988 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PLHLKKDO_02989 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PLHLKKDO_02990 2.24e-122 ywhD - - S - - - YwhD family
PLHLKKDO_02991 3.29e-154 ywhC - - S - - - Peptidase family M50
PLHLKKDO_02992 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
PLHLKKDO_02993 1.45e-93 ywhA - - K - - - Transcriptional regulator
PLHLKKDO_02994 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PLHLKKDO_02996 2.66e-263 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
PLHLKKDO_02997 6.12e-20 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
PLHLKKDO_02998 1.28e-102 yffB - - K - - - Transcriptional regulator
PLHLKKDO_02999 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
PLHLKKDO_03000 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
PLHLKKDO_03001 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
PLHLKKDO_03002 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
PLHLKKDO_03003 1.5e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
PLHLKKDO_03004 2.51e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PLHLKKDO_03005 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_03006 6.8e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
PLHLKKDO_03007 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
PLHLKKDO_03008 2.37e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
PLHLKKDO_03009 1.74e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
PLHLKKDO_03010 1.85e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
PLHLKKDO_03011 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PLHLKKDO_03012 4.47e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_03013 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PLHLKKDO_03014 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PLHLKKDO_03015 3.12e-274 ywfA - - EGP - - - -transporter
PLHLKKDO_03016 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PLHLKKDO_03017 0.0 rocB - - E - - - arginine degradation protein
PLHLKKDO_03018 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PLHLKKDO_03019 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PLHLKKDO_03020 3.7e-101 - - - - - - - -
PLHLKKDO_03021 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
PLHLKKDO_03022 4.72e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PLHLKKDO_03023 3.04e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PLHLKKDO_03024 3.04e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PLHLKKDO_03025 1.11e-237 spsG - - M - - - Spore Coat
PLHLKKDO_03026 3.51e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
PLHLKKDO_03027 4.4e-268 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
PLHLKKDO_03028 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
PLHLKKDO_03029 1.52e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
PLHLKKDO_03030 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
PLHLKKDO_03031 8.08e-187 spsA - - M - - - Spore Coat
PLHLKKDO_03032 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PLHLKKDO_03033 1.59e-78 ywdK - - S - - - small membrane protein
PLHLKKDO_03034 1.86e-303 ywdJ - - F - - - Xanthine uracil
PLHLKKDO_03035 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
PLHLKKDO_03036 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PLHLKKDO_03037 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PLHLKKDO_03038 1.57e-190 ywdF - - S - - - Glycosyltransferase like family 2
PLHLKKDO_03039 5.43e-188 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PLHLKKDO_03040 6.19e-39 ywdA - - - - - - -
PLHLKKDO_03041 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PLHLKKDO_03042 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03043 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
PLHLKKDO_03044 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PLHLKKDO_03046 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PLHLKKDO_03047 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLHLKKDO_03048 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
PLHLKKDO_03049 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PLHLKKDO_03050 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
PLHLKKDO_03051 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PLHLKKDO_03052 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PLHLKKDO_03053 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PLHLKKDO_03054 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PLHLKKDO_03055 5.11e-49 ydaS - - S - - - membrane
PLHLKKDO_03056 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
PLHLKKDO_03057 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PLHLKKDO_03058 3.33e-77 gtcA - - S - - - GtrA-like protein
PLHLKKDO_03059 4.16e-159 ywcC - - K - - - transcriptional regulator
PLHLKKDO_03061 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
PLHLKKDO_03062 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLHLKKDO_03063 1.08e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PLHLKKDO_03064 3.23e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
PLHLKKDO_03065 6.21e-249 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
PLHLKKDO_03066 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
PLHLKKDO_03067 1e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PLHLKKDO_03068 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PLHLKKDO_03069 2.7e-203 ywbI - - K - - - Transcriptional regulator
PLHLKKDO_03070 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PLHLKKDO_03071 1.21e-143 ywbG - - M - - - effector of murein hydrolase
PLHLKKDO_03072 4.13e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
PLHLKKDO_03073 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
PLHLKKDO_03074 3.29e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
PLHLKKDO_03075 3.3e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
PLHLKKDO_03076 6.24e-121 - - - N - - - domain, Protein
PLHLKKDO_03077 2.92e-160 ywbB - - S - - - Protein of unknown function (DUF2711)
PLHLKKDO_03078 3e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PLHLKKDO_03079 1.87e-272 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PLHLKKDO_03080 1.31e-09 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PLHLKKDO_03081 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03082 3.39e-191 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PLHLKKDO_03083 5.37e-216 gspA - - M - - - General stress
PLHLKKDO_03084 6.04e-159 ywaF - - S - - - Integral membrane protein
PLHLKKDO_03085 1.25e-114 ywaE - - K - - - Transcriptional regulator
PLHLKKDO_03086 6.81e-292 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PLHLKKDO_03087 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
PLHLKKDO_03088 2.67e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
PLHLKKDO_03089 2.27e-63 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PLHLKKDO_03090 3.96e-165 - - - EGP - - - Permeases of the major facilitator superfamily
PLHLKKDO_03091 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
PLHLKKDO_03092 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
PLHLKKDO_03093 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_03094 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
PLHLKKDO_03095 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_03096 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PLHLKKDO_03097 3.02e-55 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_03098 7.78e-101 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_03099 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PLHLKKDO_03100 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PLHLKKDO_03101 4.54e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03102 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PLHLKKDO_03103 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
PLHLKKDO_03104 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PLHLKKDO_03105 8.94e-28 yxzF - - - - - - -
PLHLKKDO_03106 1.87e-144 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
PLHLKKDO_03107 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PLHLKKDO_03108 3.1e-250 yxlH - - EGP - - - Major Facilitator Superfamily
PLHLKKDO_03109 5.4e-177 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PLHLKKDO_03110 3.89e-209 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_03111 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
PLHLKKDO_03112 2.92e-42 - - - - - - - -
PLHLKKDO_03113 2.34e-63 yxlC - - S - - - Family of unknown function (DUF5345)
PLHLKKDO_03114 1.06e-123 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_03115 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
PLHLKKDO_03116 1.52e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PLHLKKDO_03117 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
PLHLKKDO_03118 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
PLHLKKDO_03119 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
PLHLKKDO_03120 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PLHLKKDO_03121 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
PLHLKKDO_03122 0.0 - - - O - - - Peptidase family M48
PLHLKKDO_03124 1.77e-197 yxkH - - G - - - Polysaccharide deacetylase
PLHLKKDO_03125 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PLHLKKDO_03126 2.74e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
PLHLKKDO_03127 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PLHLKKDO_03128 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PLHLKKDO_03129 2.48e-113 - - - - - - - -
PLHLKKDO_03130 3e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PLHLKKDO_03131 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
PLHLKKDO_03132 3.76e-256 - - - T - - - Signal transduction histidine kinase
PLHLKKDO_03133 1.23e-144 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
PLHLKKDO_03134 1.57e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PLHLKKDO_03137 1.43e-111 yxjI - - S - - - LURP-one-related
PLHLKKDO_03138 5.23e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PLHLKKDO_03139 3.81e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PLHLKKDO_03140 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PLHLKKDO_03141 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PLHLKKDO_03142 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PLHLKKDO_03143 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
PLHLKKDO_03144 9.86e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
PLHLKKDO_03145 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PLHLKKDO_03146 1.78e-134 - - - T - - - Domain of unknown function (DUF4163)
PLHLKKDO_03147 7.65e-62 yxiS - - - - - - -
PLHLKKDO_03148 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PLHLKKDO_03149 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PLHLKKDO_03150 1.77e-183 bglS - - M - - - licheninase activity
PLHLKKDO_03151 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PLHLKKDO_03152 5.32e-143 - - - - - - - -
PLHLKKDO_03153 2.68e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
PLHLKKDO_03154 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PLHLKKDO_03155 4.59e-270 - - - E - - - GDSL-like Lipase/Acylhydrolase
PLHLKKDO_03158 5.34e-54 yxiJ - - S - - - YxiJ-like protein
PLHLKKDO_03159 1.27e-105 yxiI - - S - - - Protein of unknown function (DUF2716)
PLHLKKDO_03160 2.63e-177 - - - - - - - -
PLHLKKDO_03161 2.81e-90 yxiG - - - - - - -
PLHLKKDO_03162 3.49e-77 - - - - - - - -
PLHLKKDO_03163 1.5e-110 - - - - - - - -
PLHLKKDO_03164 1.09e-94 yxxG - - - - - - -
PLHLKKDO_03165 0.0 wapA - - M - - - COG3209 Rhs family protein
PLHLKKDO_03166 2.94e-210 yxxF - - EG - - - EamA-like transporter family
PLHLKKDO_03167 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
PLHLKKDO_03168 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PLHLKKDO_03169 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03170 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
PLHLKKDO_03171 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
PLHLKKDO_03172 1.89e-52 yxiC - - S - - - Family of unknown function (DUF5344)
PLHLKKDO_03173 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
PLHLKKDO_03174 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PLHLKKDO_03175 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PLHLKKDO_03176 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
PLHLKKDO_03177 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PLHLKKDO_03178 1.64e-301 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
PLHLKKDO_03179 4.85e-231 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
PLHLKKDO_03180 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PLHLKKDO_03181 1.91e-297 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
PLHLKKDO_03182 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PLHLKKDO_03183 6.82e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PLHLKKDO_03184 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PLHLKKDO_03185 1.84e-197 - - - S - - - Domain of Unknown Function (DUF1206)
PLHLKKDO_03186 8.06e-258 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
PLHLKKDO_03187 1.45e-314 yxeQ - - S - - - MmgE/PrpD family
PLHLKKDO_03188 4.1e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
PLHLKKDO_03189 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_03190 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PLHLKKDO_03191 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PLHLKKDO_03192 2.55e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PLHLKKDO_03193 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLHLKKDO_03194 3.05e-234 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
PLHLKKDO_03195 8.09e-194 yxeH - - S - - - hydrolases of the HAD superfamily
PLHLKKDO_03198 7.32e-42 yxeE - - - - - - -
PLHLKKDO_03199 7.57e-28 yxeD - - - - - - -
PLHLKKDO_03200 9.65e-91 - - - - - - - -
PLHLKKDO_03201 4.1e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PLHLKKDO_03202 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
PLHLKKDO_03203 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PLHLKKDO_03204 3.82e-181 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_03205 1.1e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_03206 3.27e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_03207 1.64e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PLHLKKDO_03208 3.79e-187 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PLHLKKDO_03209 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
PLHLKKDO_03210 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PLHLKKDO_03211 4.68e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
PLHLKKDO_03212 1.74e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PLHLKKDO_03213 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PLHLKKDO_03214 2.13e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PLHLKKDO_03215 9.89e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PLHLKKDO_03216 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PLHLKKDO_03217 2.6e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PLHLKKDO_03218 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
PLHLKKDO_03220 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
PLHLKKDO_03221 4.16e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PLHLKKDO_03222 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
PLHLKKDO_03224 9.79e-192 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PLHLKKDO_03225 1.71e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
PLHLKKDO_03226 1.69e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PLHLKKDO_03227 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
PLHLKKDO_03228 4.71e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
PLHLKKDO_03229 1.76e-175 yxbB - - Q - - - Met-10+ like-protein
PLHLKKDO_03230 1.49e-58 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
PLHLKKDO_03231 8.99e-114 yxnB - - - - - - -
PLHLKKDO_03232 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PLHLKKDO_03233 1.8e-271 yxaM - - U - - - MFS_1 like family
PLHLKKDO_03234 1.6e-133 yxaL - - S - - - PQQ-like domain
PLHLKKDO_03235 1.38e-83 - - - S - - - Family of unknown function (DUF5391)
PLHLKKDO_03236 4.03e-99 yxaI - - S - - - membrane protein domain
PLHLKKDO_03237 3.75e-286 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
PLHLKKDO_03238 1.05e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
PLHLKKDO_03239 3.91e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PLHLKKDO_03240 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PLHLKKDO_03241 3.95e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PLHLKKDO_03242 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
PLHLKKDO_03243 1.27e-152 yxaC - - M - - - effector of murein hydrolase
PLHLKKDO_03244 8.52e-244 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
PLHLKKDO_03245 4.71e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PLHLKKDO_03246 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
PLHLKKDO_03247 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
PLHLKKDO_03248 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
PLHLKKDO_03249 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PLHLKKDO_03250 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
PLHLKKDO_03251 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
PLHLKKDO_03253 7.79e-56 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PLHLKKDO_03254 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
PLHLKKDO_03255 7.13e-161 - - - S - - - AIPR protein
PLHLKKDO_03256 7.91e-205 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
PLHLKKDO_03257 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PLHLKKDO_03259 1.77e-84 - - - - - - - -
PLHLKKDO_03260 1.05e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PLHLKKDO_03262 1.7e-45 yycQ - - S - - - Protein of unknown function (DUF2651)
PLHLKKDO_03263 1.77e-281 yycP - - - - - - -
PLHLKKDO_03264 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PLHLKKDO_03265 8.71e-110 yycN - - K - - - Acetyltransferase
PLHLKKDO_03266 5.02e-238 - - - S - - - aspartate phosphatase
PLHLKKDO_03268 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PLHLKKDO_03269 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PLHLKKDO_03270 1.5e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
PLHLKKDO_03271 5.82e-20 - - - - - - - -
PLHLKKDO_03272 1.7e-119 - - - - - - - -
PLHLKKDO_03273 2.74e-31 - - - S - - - Sporulation delaying protein SdpA
PLHLKKDO_03274 2.27e-86 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
PLHLKKDO_03275 5.02e-55 sdpR - - K - - - transcriptional
PLHLKKDO_03276 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PLHLKKDO_03277 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLHLKKDO_03278 4.68e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PLHLKKDO_03279 1.63e-198 yycI - - S - - - protein conserved in bacteria
PLHLKKDO_03280 0.0 yycH - - S - - - protein conserved in bacteria
PLHLKKDO_03281 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_03282 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_03287 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PLHLKKDO_03288 3.29e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PLHLKKDO_03289 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PLHLKKDO_03290 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
PLHLKKDO_03292 1.89e-22 yycC - - K - - - YycC-like protein
PLHLKKDO_03293 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
PLHLKKDO_03294 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PLHLKKDO_03295 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PLHLKKDO_03296 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
PLHLKKDO_03297 1.5e-204 yybS - - S - - - membrane
PLHLKKDO_03299 6.83e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
PLHLKKDO_03300 6.43e-88 yybR - - K - - - Transcriptional regulator
PLHLKKDO_03301 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
PLHLKKDO_03302 3.67e-80 - - - - - - - -
PLHLKKDO_03304 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_03305 4.38e-142 - - - K - - - TipAS antibiotic-recognition domain
PLHLKKDO_03306 9.72e-182 - - - - - - - -
PLHLKKDO_03307 5.02e-87 - - - S - - - SnoaL-like domain
PLHLKKDO_03308 2.31e-161 yybG - - S - - - Pentapeptide repeat-containing protein
PLHLKKDO_03309 2.9e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_03310 7.57e-210 yybE - - K - - - Transcriptional regulator
PLHLKKDO_03311 2.18e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
PLHLKKDO_03312 1.66e-95 yybC - - - - - - -
PLHLKKDO_03313 1.03e-162 - - - S - - - Metallo-beta-lactamase superfamily
PLHLKKDO_03314 4.54e-100 yybA - - K - - - transcriptional
PLHLKKDO_03315 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
PLHLKKDO_03316 1.01e-123 yyaS - - S ko:K07149 - ko00000 Membrane
PLHLKKDO_03317 2.72e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
PLHLKKDO_03318 1.05e-85 - - - S - - - YjbR
PLHLKKDO_03319 2.89e-135 yyaP - - H - - - RibD C-terminal domain
PLHLKKDO_03320 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_03321 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
PLHLKKDO_03322 1.16e-212 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
PLHLKKDO_03323 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
PLHLKKDO_03324 3.81e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
PLHLKKDO_03325 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PLHLKKDO_03326 2.05e-228 ccpB - - K - - - Transcriptional regulator
PLHLKKDO_03327 7.76e-183 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
PLHLKKDO_03328 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PLHLKKDO_03329 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PLHLKKDO_03330 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PLHLKKDO_03331 1.89e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PLHLKKDO_03332 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PLHLKKDO_03333 7.41e-45 yyzM - - S - - - protein conserved in bacteria
PLHLKKDO_03334 1.08e-226 yyaD - - S - - - Membrane
PLHLKKDO_03335 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
PLHLKKDO_03336 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PLHLKKDO_03337 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
PLHLKKDO_03338 9.26e-98 - - - S - - - Bacterial PH domain
PLHLKKDO_03339 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PLHLKKDO_03340 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PLHLKKDO_03341 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PLHLKKDO_03342 4.53e-316 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PLHLKKDO_03343 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
PLHLKKDO_03344 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PLHLKKDO_03345 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PLHLKKDO_03346 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PLHLKKDO_03347 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PLHLKKDO_03348 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
PLHLKKDO_03349 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PLHLKKDO_03350 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
PLHLKKDO_03351 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PLHLKKDO_03352 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PLHLKKDO_03353 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PLHLKKDO_03354 3.47e-205 ybaS - - S - - - Na -dependent transporter
PLHLKKDO_03355 1.91e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
PLHLKKDO_03356 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_03357 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_03358 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
PLHLKKDO_03359 8.71e-296 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
PLHLKKDO_03360 1.32e-27 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
PLHLKKDO_03361 8.49e-305 ybbC - - S - - - protein conserved in bacteria
PLHLKKDO_03362 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
PLHLKKDO_03363 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
PLHLKKDO_03364 2.97e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03365 1.28e-192 ybbH - - K - - - transcriptional
PLHLKKDO_03366 1.64e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PLHLKKDO_03367 1.81e-113 ybbJ - - J - - - acetyltransferase
PLHLKKDO_03368 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
PLHLKKDO_03374 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_03375 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PLHLKKDO_03376 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PLHLKKDO_03377 3.41e-291 ybbR - - S - - - protein conserved in bacteria
PLHLKKDO_03378 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PLHLKKDO_03379 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PLHLKKDO_03380 5.38e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PLHLKKDO_03381 1.71e-152 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
PLHLKKDO_03382 1.06e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PLHLKKDO_03383 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PLHLKKDO_03384 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
PLHLKKDO_03385 1.51e-117 ybcF - - P - - - carbonic anhydrase
PLHLKKDO_03386 4.6e-63 - - - - - - - -
PLHLKKDO_03387 1.7e-77 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
PLHLKKDO_03388 3.17e-65 - - - K - - - Helix-turn-helix domain
PLHLKKDO_03389 5.18e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
PLHLKKDO_03391 1.21e-21 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PLHLKKDO_03392 7.04e-139 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
PLHLKKDO_03393 6.48e-50 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
PLHLKKDO_03395 6.47e-176 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
PLHLKKDO_03396 9.03e-230 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PLHLKKDO_03397 6.9e-158 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
PLHLKKDO_03398 2.28e-218 - - - T - - - His Kinase A (phospho-acceptor) domain
PLHLKKDO_03400 4.82e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
PLHLKKDO_03401 3.67e-193 ybdN - - - - - - -
PLHLKKDO_03402 8.98e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
PLHLKKDO_03403 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PLHLKKDO_03404 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
PLHLKKDO_03405 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
PLHLKKDO_03406 4.15e-190 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
PLHLKKDO_03407 1.81e-312 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
PLHLKKDO_03408 1.11e-54 ybyB - - - - - - -
PLHLKKDO_03409 0.0 ybeC - - E - - - amino acid
PLHLKKDO_03410 1.09e-54 - - - M - - - PFAM Glycosyl transferase family 2
PLHLKKDO_03411 3.32e-205 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
PLHLKKDO_03412 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
PLHLKKDO_03413 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
PLHLKKDO_03414 6.75e-215 ybfA - - K - - - FR47-like protein
PLHLKKDO_03415 7.88e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_03416 8.74e-207 ybfH - - EG - - - EamA-like transporter family
PLHLKKDO_03417 1.23e-186 ybfI - - K - - - AraC-like ligand binding domain
PLHLKKDO_03418 1.95e-272 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PLHLKKDO_03419 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
PLHLKKDO_03421 1.37e-214 - - - S - - - Alpha/beta hydrolase family
PLHLKKDO_03422 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PLHLKKDO_03423 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
PLHLKKDO_03424 1.45e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PLHLKKDO_03425 2.33e-61 ybfN - - - - - - -
PLHLKKDO_03426 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
PLHLKKDO_03427 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
PLHLKKDO_03428 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PLHLKKDO_03429 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03430 1.43e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PLHLKKDO_03431 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
PLHLKKDO_03433 3.08e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PLHLKKDO_03434 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PLHLKKDO_03435 1.51e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
PLHLKKDO_03436 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PLHLKKDO_03437 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PLHLKKDO_03438 2.05e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_03439 4.94e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
PLHLKKDO_03440 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
PLHLKKDO_03441 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PLHLKKDO_03442 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_03443 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PLHLKKDO_03444 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
PLHLKKDO_03445 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
PLHLKKDO_03446 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
PLHLKKDO_03447 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
PLHLKKDO_03448 3.2e-216 eamA1 - - EG - - - spore germination
PLHLKKDO_03449 2.61e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_03450 6.21e-214 ycbM - - T - - - Histidine kinase
PLHLKKDO_03451 1.07e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_03452 1.36e-146 - - - S - - - ABC-2 family transporter protein
PLHLKKDO_03453 5.22e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
PLHLKKDO_03454 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
PLHLKKDO_03455 1.56e-173 ycbR - - T - - - vWA found in TerF C terminus
PLHLKKDO_03456 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
PLHLKKDO_03457 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PLHLKKDO_03458 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PLHLKKDO_03459 1.99e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PLHLKKDO_03460 1.45e-260 ycbU - - E - - - Selenocysteine lyase
PLHLKKDO_03461 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
PLHLKKDO_03462 1.54e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PLHLKKDO_03463 1.69e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PLHLKKDO_03464 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PLHLKKDO_03465 8.72e-78 - - - S - - - RDD family
PLHLKKDO_03466 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
PLHLKKDO_03467 2.62e-214 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PLHLKKDO_03468 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PLHLKKDO_03469 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PLHLKKDO_03470 4.53e-166 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PLHLKKDO_03471 6.81e-222 yccK - - C - - - Aldo keto reductase
PLHLKKDO_03472 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
PLHLKKDO_03473 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_03474 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_03475 2.18e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PLHLKKDO_03476 1.16e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
PLHLKKDO_03477 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
PLHLKKDO_03478 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PLHLKKDO_03479 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PLHLKKDO_03480 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PLHLKKDO_03481 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PLHLKKDO_03482 4.19e-238 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLHLKKDO_03483 3.75e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
PLHLKKDO_03484 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PLHLKKDO_03485 1e-137 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PLHLKKDO_03486 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
PLHLKKDO_03487 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
PLHLKKDO_03488 2.96e-245 yceH - - P - - - Belongs to the TelA family
PLHLKKDO_03489 1.9e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
PLHLKKDO_03490 1.42e-204 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
PLHLKKDO_03491 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PLHLKKDO_03492 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
PLHLKKDO_03493 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PLHLKKDO_03494 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PLHLKKDO_03495 6.87e-277 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
PLHLKKDO_03496 0.0 ycgA - - S - - - Membrane
PLHLKKDO_03497 1.25e-127 ycgB - - - - - - -
PLHLKKDO_03498 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
PLHLKKDO_03499 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PLHLKKDO_03500 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PLHLKKDO_03501 0.0 mdr - - EGP - - - the major facilitator superfamily
PLHLKKDO_03502 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
PLHLKKDO_03503 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
PLHLKKDO_03504 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
PLHLKKDO_03505 1.86e-316 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PLHLKKDO_03506 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
PLHLKKDO_03507 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PLHLKKDO_03508 5.13e-138 tmrB - - S - - - AAA domain
PLHLKKDO_03509 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PLHLKKDO_03510 2.06e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
PLHLKKDO_03511 9.74e-229 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
PLHLKKDO_03512 2.7e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
PLHLKKDO_03513 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
PLHLKKDO_03514 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PLHLKKDO_03515 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PLHLKKDO_03516 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLHLKKDO_03517 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
PLHLKKDO_03518 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
PLHLKKDO_03519 1.3e-186 ycgR - - S ko:K07089 - ko00000 permeases
PLHLKKDO_03520 7.55e-206 ycgS - - I - - - alpha/beta hydrolase fold
PLHLKKDO_03521 3.33e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
PLHLKKDO_03522 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PLHLKKDO_03523 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
PLHLKKDO_03524 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PLHLKKDO_03525 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PLHLKKDO_03526 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
PLHLKKDO_03527 3.18e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
PLHLKKDO_03528 3.23e-217 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
PLHLKKDO_03529 9.38e-132 - - - M - - - ErfK YbiS YcfS YnhG
PLHLKKDO_03530 1.94e-290 yciC - - S - - - GTPases (G3E family)
PLHLKKDO_03531 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PLHLKKDO_03532 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PLHLKKDO_03533 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
PLHLKKDO_03534 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PLHLKKDO_03535 3.36e-91 nin - - S - - - Competence protein J (ComJ)
PLHLKKDO_03536 2.77e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
PLHLKKDO_03537 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PLHLKKDO_03538 1.38e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
PLHLKKDO_03539 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
PLHLKKDO_03540 6.05e-86 hxlR - - K - - - transcriptional
PLHLKKDO_03541 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_03542 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PLHLKKDO_03543 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
PLHLKKDO_03544 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
PLHLKKDO_03545 4.41e-288 - - - EGP - - - Major Facilitator Superfamily
PLHLKKDO_03546 8.93e-124 - - - S - - - YcxB-like protein
PLHLKKDO_03547 1.62e-205 ycxC - - EG - - - EamA-like transporter family
PLHLKKDO_03548 1.87e-316 ycxD - - K - - - GntR family transcriptional regulator
PLHLKKDO_03549 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
PLHLKKDO_03550 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
PLHLKKDO_03551 3.38e-170 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PLHLKKDO_03552 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PLHLKKDO_03553 3.03e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PLHLKKDO_03554 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
PLHLKKDO_03555 1.35e-141 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PLHLKKDO_03556 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PLHLKKDO_03557 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
PLHLKKDO_03558 2.32e-104 yclD - - - - - - -
PLHLKKDO_03559 1.16e-203 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
PLHLKKDO_03560 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
PLHLKKDO_03561 0.0 yclG - - M - - - Pectate lyase superfamily protein
PLHLKKDO_03563 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
PLHLKKDO_03564 4.83e-296 gerKC - - S ko:K06297 - ko00000 spore germination
PLHLKKDO_03565 1.55e-252 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
PLHLKKDO_03566 1.18e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PLHLKKDO_03567 2.64e-278 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
PLHLKKDO_03568 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PLHLKKDO_03569 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PLHLKKDO_03570 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PLHLKKDO_03572 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PLHLKKDO_03573 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PLHLKKDO_03574 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_03575 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_03576 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_03577 3.3e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
PLHLKKDO_03578 0.0 ycnB - - EGP - - - the major facilitator superfamily
PLHLKKDO_03579 5.87e-198 ycnC - - K - - - Transcriptional regulator
PLHLKKDO_03580 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PLHLKKDO_03581 1.68e-60 ycnE - - S - - - Monooxygenase
PLHLKKDO_03582 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PLHLKKDO_03583 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PLHLKKDO_03584 1.97e-312 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PLHLKKDO_03585 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PLHLKKDO_03586 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
PLHLKKDO_03587 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_03588 3.99e-134 ycnI - - S - - - protein conserved in bacteria
PLHLKKDO_03589 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
PLHLKKDO_03590 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PLHLKKDO_03591 1.34e-74 - - - - - - - -
PLHLKKDO_03592 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
PLHLKKDO_03593 3.38e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PLHLKKDO_03594 2.97e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
PLHLKKDO_03595 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
PLHLKKDO_03597 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PLHLKKDO_03598 1.41e-142 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
PLHLKKDO_03599 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
PLHLKKDO_03601 1.1e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PLHLKKDO_03602 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
PLHLKKDO_03603 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
PLHLKKDO_03604 8.18e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
PLHLKKDO_03605 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
PLHLKKDO_03606 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
PLHLKKDO_03607 3.8e-171 kipR - - K - - - Transcriptional regulator
PLHLKKDO_03608 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
PLHLKKDO_03610 7.67e-66 yczJ - - S - - - biosynthesis
PLHLKKDO_03611 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
PLHLKKDO_03612 8.6e-220 ycsN - - S - - - Oxidoreductase
PLHLKKDO_03613 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
PLHLKKDO_03614 0.0 ydaB - - IQ - - - acyl-CoA ligase
PLHLKKDO_03615 1.43e-127 ydaC - - Q - - - Methyltransferase domain
PLHLKKDO_03616 3.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_03617 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
PLHLKKDO_03618 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PLHLKKDO_03619 5.24e-101 ydaG - - S - - - general stress protein
PLHLKKDO_03620 4.39e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PLHLKKDO_03621 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
PLHLKKDO_03622 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PLHLKKDO_03623 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PLHLKKDO_03624 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
PLHLKKDO_03625 1.33e-194 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
PLHLKKDO_03626 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
PLHLKKDO_03627 7.86e-304 ydaM - - M - - - Glycosyl transferase family group 2
PLHLKKDO_03628 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
PLHLKKDO_03629 0.0 ydaO - - E - - - amino acid
PLHLKKDO_03630 3.08e-102 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PLHLKKDO_03631 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PLHLKKDO_03633 1.84e-34 - - - - - - - -
PLHLKKDO_03634 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
PLHLKKDO_03636 2.14e-53 - - - - - - - -
PLHLKKDO_03637 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PLHLKKDO_03638 1.67e-42 ydaS - - S - - - membrane
PLHLKKDO_03639 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
PLHLKKDO_03640 1.75e-189 ydbA - - P - - - EcsC protein family
PLHLKKDO_03641 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
PLHLKKDO_03642 7.58e-79 ydbB - - G - - - Cupin domain
PLHLKKDO_03643 1.28e-82 ydbC - - S - - - Domain of unknown function (DUF4937
PLHLKKDO_03644 2.24e-197 ydbD - - P ko:K07217 - ko00000 Catalase
PLHLKKDO_03645 4.28e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PLHLKKDO_03646 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PLHLKKDO_03647 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PLHLKKDO_03648 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PLHLKKDO_03649 4.41e-229 ydbI - - S - - - AI-2E family transporter
PLHLKKDO_03650 1.08e-217 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_03651 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PLHLKKDO_03652 9.32e-70 ydbL - - - - - - -
PLHLKKDO_03653 3.54e-278 ydbM - - I - - - acyl-CoA dehydrogenase
PLHLKKDO_03654 1.49e-26 - - - S - - - Fur-regulated basic protein B
PLHLKKDO_03655 2.1e-11 - - - S - - - Fur-regulated basic protein A
PLHLKKDO_03656 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PLHLKKDO_03657 4.19e-75 ydbP - - CO - - - Thioredoxin
PLHLKKDO_03658 8.43e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PLHLKKDO_03659 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PLHLKKDO_03660 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PLHLKKDO_03661 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
PLHLKKDO_03662 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
PLHLKKDO_03663 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
PLHLKKDO_03664 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PLHLKKDO_03665 1.9e-233 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
PLHLKKDO_03666 1.39e-279 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PLHLKKDO_03667 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PLHLKKDO_03668 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
PLHLKKDO_03669 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
PLHLKKDO_03670 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
PLHLKKDO_03671 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PLHLKKDO_03672 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
PLHLKKDO_03673 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
PLHLKKDO_03674 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PLHLKKDO_03675 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLHLKKDO_03676 7.57e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
PLHLKKDO_03677 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
PLHLKKDO_03678 4.55e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
PLHLKKDO_03679 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
PLHLKKDO_03680 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PLHLKKDO_03681 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PLHLKKDO_03682 2.15e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
PLHLKKDO_03683 1.95e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
PLHLKKDO_03684 1.9e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
PLHLKKDO_03685 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
PLHLKKDO_03686 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
PLHLKKDO_03687 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_03688 1.33e-161 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PLHLKKDO_03689 9.36e-310 yfnA - - E ko:K03294 - ko00000 amino acid
PLHLKKDO_03690 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PLHLKKDO_03691 5.14e-161 yfmS - - NT - - - chemotaxis protein
PLHLKKDO_03692 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PLHLKKDO_03693 3.75e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
PLHLKKDO_03694 1.44e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
PLHLKKDO_03695 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
PLHLKKDO_03696 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PLHLKKDO_03697 1.2e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
PLHLKKDO_03698 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
PLHLKKDO_03699 6.98e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
PLHLKKDO_03700 3.46e-268 - - - G - - - Major Facilitator Superfamily
PLHLKKDO_03701 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
PLHLKKDO_03702 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PLHLKKDO_03703 3.47e-222 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_03704 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_03705 7.58e-217 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PLHLKKDO_03706 4.26e-31 - - - S - - - Protein of unknown function (DUF3212)
PLHLKKDO_03707 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
PLHLKKDO_03708 3.34e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
PLHLKKDO_03709 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PLHLKKDO_03710 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PLHLKKDO_03711 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
PLHLKKDO_03712 1.97e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
PLHLKKDO_03713 1.53e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PLHLKKDO_03714 7.21e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PLHLKKDO_03715 1.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PLHLKKDO_03716 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
PLHLKKDO_03717 2.51e-159 yflK - - S - - - protein conserved in bacteria
PLHLKKDO_03718 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
PLHLKKDO_03719 2.82e-26 yflI - - - - - - -
PLHLKKDO_03720 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
PLHLKKDO_03721 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PLHLKKDO_03722 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PLHLKKDO_03723 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PLHLKKDO_03724 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
PLHLKKDO_03725 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
PLHLKKDO_03726 9.97e-246 yfkT - - E ko:K06309 - ko00000 Spore germination protein
PLHLKKDO_03728 6.53e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
PLHLKKDO_03729 3.61e-299 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
PLHLKKDO_03730 2.2e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
PLHLKKDO_03731 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03732 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
PLHLKKDO_03733 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
PLHLKKDO_03734 6.16e-160 frp - - C - - - nitroreductase
PLHLKKDO_03735 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PLHLKKDO_03736 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PLHLKKDO_03737 1.03e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_03738 2.97e-41 yfkK - - S - - - Belongs to the UPF0435 family
PLHLKKDO_03739 5.04e-109 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PLHLKKDO_03740 4.21e-66 yfkI - - S - - - gas vesicle protein
PLHLKKDO_03741 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
PLHLKKDO_03742 1.64e-12 - - - - - - - -
PLHLKKDO_03743 3.84e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PLHLKKDO_03744 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
PLHLKKDO_03745 3.69e-189 yfkD - - S - - - YfkD-like protein
PLHLKKDO_03746 8.97e-191 yfkC - - M - - - Mechanosensitive ion channel
PLHLKKDO_03747 1.76e-283 yfkA - - S - - - YfkB-like domain
PLHLKKDO_03748 3.26e-36 yfjT - - - - - - -
PLHLKKDO_03749 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
PLHLKKDO_03750 1.38e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PLHLKKDO_03751 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
PLHLKKDO_03752 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PLHLKKDO_03753 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PLHLKKDO_03754 3.04e-59 - - - S - - - YfzA-like protein
PLHLKKDO_03755 1.25e-236 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PLHLKKDO_03756 1.47e-105 yfjM - - S - - - Psort location Cytoplasmic, score
PLHLKKDO_03757 1.94e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PLHLKKDO_03758 4.37e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PLHLKKDO_03759 6.94e-264 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PLHLKKDO_03760 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PLHLKKDO_03761 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
PLHLKKDO_03762 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
PLHLKKDO_03763 1.23e-73 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
PLHLKKDO_03764 1.34e-109 - - - S - - - Family of unknown function (DUF5381)
PLHLKKDO_03765 1.45e-159 yfjC - - - - - - -
PLHLKKDO_03766 5.94e-242 yfjB - - - - - - -
PLHLKKDO_03767 1.87e-59 yfjA - - S - - - Belongs to the WXG100 family
PLHLKKDO_03768 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PLHLKKDO_03769 8.69e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
PLHLKKDO_03770 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03771 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
PLHLKKDO_03772 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PLHLKKDO_03773 3.34e-83 yfiD3 - - S - - - DoxX
PLHLKKDO_03774 4.21e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
PLHLKKDO_03776 1.98e-271 baeS - - T - - - Histidine kinase
PLHLKKDO_03777 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
PLHLKKDO_03778 7.89e-217 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PLHLKKDO_03779 4.18e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PLHLKKDO_03780 5.45e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PLHLKKDO_03781 2.21e-127 padR - - K - - - transcriptional
PLHLKKDO_03782 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PLHLKKDO_03783 2.29e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PLHLKKDO_03784 9.43e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
PLHLKKDO_03785 0.0 yfiU - - EGP - - - the major facilitator superfamily
PLHLKKDO_03786 1.04e-103 yfiV - - K - - - transcriptional
PLHLKKDO_03787 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PLHLKKDO_03788 5e-227 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PLHLKKDO_03789 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_03790 7.05e-227 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLHLKKDO_03791 2.09e-212 yfhB - - S - - - PhzF family
PLHLKKDO_03792 2.87e-138 yfhC - - C - - - nitroreductase
PLHLKKDO_03793 8.86e-35 yfhD - - S - - - YfhD-like protein
PLHLKKDO_03795 2.19e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
PLHLKKDO_03796 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
PLHLKKDO_03797 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
PLHLKKDO_03798 8.17e-267 yfhI - - EGP - - - -transporter
PLHLKKDO_03799 7.57e-26 sspK - - S ko:K06428 - ko00000 reproduction
PLHLKKDO_03800 8.95e-60 yfhJ - - S - - - WVELL protein
PLHLKKDO_03801 2.32e-115 yfhK - - T - - - Bacterial SH3 domain homologues
PLHLKKDO_03802 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
PLHLKKDO_03803 1.08e-215 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
PLHLKKDO_03804 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PLHLKKDO_03805 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
PLHLKKDO_03806 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
PLHLKKDO_03807 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
PLHLKKDO_03808 4.96e-48 yfhS - - - - - - -
PLHLKKDO_03809 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PLHLKKDO_03810 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
PLHLKKDO_03811 2.01e-49 ygaB - - S - - - YgaB-like protein
PLHLKKDO_03812 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
PLHLKKDO_03813 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
PLHLKKDO_03814 2.65e-238 ygaE - - S - - - Membrane
PLHLKKDO_03815 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PLHLKKDO_03816 8.36e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
PLHLKKDO_03817 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
PLHLKKDO_03818 3.38e-73 ygzB - - S - - - UPF0295 protein
PLHLKKDO_03819 2.36e-214 ygxA - - S - - - Nucleotidyltransferase-like
PLHLKKDO_03820 1.43e-226 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PLHLKKDO_03821 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
PLHLKKDO_03822 2.4e-161 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
PLHLKKDO_03823 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PLHLKKDO_03824 5.46e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PLHLKKDO_03825 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
PLHLKKDO_03826 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PLHLKKDO_03827 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PLHLKKDO_03828 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PLHLKKDO_03829 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PLHLKKDO_03830 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
PLHLKKDO_03831 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
PLHLKKDO_03832 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PLHLKKDO_03833 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PLHLKKDO_03834 1.55e-192 ydjC - - S - - - Abhydrolase domain containing 18
PLHLKKDO_03835 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
PLHLKKDO_03836 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
PLHLKKDO_03837 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
PLHLKKDO_03838 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
PLHLKKDO_03839 9.24e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
PLHLKKDO_03840 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PLHLKKDO_03841 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
PLHLKKDO_03842 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
PLHLKKDO_03843 1.37e-248 - - - S - - - Ion transport 2 domain protein
PLHLKKDO_03844 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PLHLKKDO_03845 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
PLHLKKDO_03846 1.79e-84 ydjM - - M - - - Lytic transglycolase
PLHLKKDO_03847 9.38e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
PLHLKKDO_03849 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
PLHLKKDO_03850 1.85e-204 - - - I - - - Alpha/beta hydrolase family
PLHLKKDO_03851 7.12e-229 yeaA - - S - - - Protein of unknown function (DUF4003)
PLHLKKDO_03852 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
PLHLKKDO_03853 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PLHLKKDO_03854 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PLHLKKDO_03855 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
PLHLKKDO_03856 1.36e-286 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PLHLKKDO_03857 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
PLHLKKDO_03858 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PLHLKKDO_03859 3.8e-112 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PLHLKKDO_03860 0.0 - - - S - - - Domain of unknown function (DUF4179)
PLHLKKDO_03861 2.81e-282 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PLHLKKDO_03862 5.85e-165 yebC - - M - - - Membrane
PLHLKKDO_03864 1.08e-119 yebE - - S - - - UPF0316 protein
PLHLKKDO_03865 3.13e-38 yebG - - S - - - NETI protein
PLHLKKDO_03866 7.63e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PLHLKKDO_03867 9e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PLHLKKDO_03868 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PLHLKKDO_03869 2.78e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
PLHLKKDO_03870 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PLHLKKDO_03871 6.66e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PLHLKKDO_03872 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PLHLKKDO_03873 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PLHLKKDO_03874 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PLHLKKDO_03875 4.22e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PLHLKKDO_03876 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
PLHLKKDO_03877 1.4e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
PLHLKKDO_03878 1.29e-94 - - - K - - - helix_turn_helix ASNC type
PLHLKKDO_03879 9.05e-296 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
PLHLKKDO_03880 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
PLHLKKDO_03881 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
PLHLKKDO_03882 7.03e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
PLHLKKDO_03883 7.62e-68 yerC - - S - - - protein conserved in bacteria
PLHLKKDO_03884 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
PLHLKKDO_03886 7.43e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PLHLKKDO_03887 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
PLHLKKDO_03888 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PLHLKKDO_03889 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
PLHLKKDO_03890 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
PLHLKKDO_03891 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
PLHLKKDO_03892 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLHLKKDO_03893 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PLHLKKDO_03894 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PLHLKKDO_03895 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PLHLKKDO_03896 2.43e-189 yerO - - K - - - Transcriptional regulator
PLHLKKDO_03897 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLHLKKDO_03898 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PLHLKKDO_03899 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PLHLKKDO_03900 2.31e-194 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
PLHLKKDO_03901 8.68e-60 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
PLHLKKDO_03902 3.45e-123 - - - - - - - -
PLHLKKDO_03903 6.17e-111 - - - V - - - Restriction endonuclease
PLHLKKDO_03905 1.05e-122 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PLHLKKDO_03906 6.94e-54 - - - S - - - Immunity protein 22
PLHLKKDO_03907 8.28e-228 - - - S - - - Bacterial EndoU nuclease
PLHLKKDO_03909 2.44e-127 - - - L - - - endonuclease activity
PLHLKKDO_03910 2.99e-212 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
PLHLKKDO_03911 9.61e-269 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
PLHLKKDO_03913 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
PLHLKKDO_03915 9.93e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
PLHLKKDO_03916 8.23e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
PLHLKKDO_03917 1.23e-195 yesF - - GM - - - NAD(P)H-binding
PLHLKKDO_03918 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
PLHLKKDO_03919 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
PLHLKKDO_03920 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
PLHLKKDO_03921 4.15e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
PLHLKKDO_03923 6.29e-133 yesL - - S - - - Protein of unknown function, DUF624
PLHLKKDO_03924 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_03925 2.81e-257 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
PLHLKKDO_03926 1.38e-312 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PLHLKKDO_03927 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PLHLKKDO_03928 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PLHLKKDO_03929 1.96e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
PLHLKKDO_03930 0.0 yesS - - K - - - Transcriptional regulator
PLHLKKDO_03931 3.56e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
PLHLKKDO_03932 1.41e-169 yesU - - S - - - Domain of unknown function (DUF1961)
PLHLKKDO_03933 3.44e-146 - - - S - - - Protein of unknown function, DUF624
PLHLKKDO_03934 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
PLHLKKDO_03935 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
PLHLKKDO_03936 3.13e-83 - - - E - - - GDSL-like Lipase/Acylhydrolase
PLHLKKDO_03937 3.62e-45 - - - E - - - GDSL-like Lipase/Acylhydrolase
PLHLKKDO_03938 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
PLHLKKDO_03939 0.0 yetA - - - - - - -
PLHLKKDO_03940 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PLHLKKDO_03941 9.71e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
PLHLKKDO_03942 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PLHLKKDO_03943 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
PLHLKKDO_03944 1.49e-156 yetF - - S - - - membrane
PLHLKKDO_03945 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
PLHLKKDO_03946 7.08e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PLHLKKDO_03947 9.79e-45 - - - - - - - -
PLHLKKDO_03948 3.08e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PLHLKKDO_03949 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
PLHLKKDO_03950 2.1e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
PLHLKKDO_03951 2.26e-115 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
PLHLKKDO_03952 1.78e-265 yetM - - CH - - - FAD binding domain
PLHLKKDO_03954 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
PLHLKKDO_03955 2.64e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
PLHLKKDO_03956 1.46e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PLHLKKDO_03957 7.86e-211 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
PLHLKKDO_03958 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
PLHLKKDO_03959 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PLHLKKDO_03960 7.59e-304 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PLHLKKDO_03961 1.44e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03962 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PLHLKKDO_03963 2.56e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
PLHLKKDO_03964 3.29e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
PLHLKKDO_03965 9.03e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PLHLKKDO_03966 3.25e-109 - - - K - - - Acetyltransferase (GNAT) domain
PLHLKKDO_03968 3.33e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
PLHLKKDO_03969 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PLHLKKDO_03970 2.89e-161 - - - - - - - -
PLHLKKDO_03971 9.21e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PLHLKKDO_03972 4.24e-308 ydhD - - M - - - Glycosyl hydrolase
PLHLKKDO_03973 5.24e-158 ydhC - - K - - - FCD
PLHLKKDO_03974 7.2e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
PLHLKKDO_03975 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
PLHLKKDO_03976 1.9e-89 - - - K - - - Winged helix DNA-binding domain
PLHLKKDO_03977 1.51e-145 ydgI - - C - - - nitroreductase
PLHLKKDO_03978 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
PLHLKKDO_03979 2.92e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PLHLKKDO_03980 1.2e-117 - - - S - - - DinB family
PLHLKKDO_03981 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PLHLKKDO_03982 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
PLHLKKDO_03983 2.46e-68 yycN - - K - - - Acetyltransferase
PLHLKKDO_03984 1.93e-68 - - - S - - - DoxX-like family
PLHLKKDO_03985 3.71e-122 ydgC - - K - - - Bacterial regulatory proteins, tetR family
PLHLKKDO_03986 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
PLHLKKDO_03987 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
PLHLKKDO_03988 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PLHLKKDO_03989 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
PLHLKKDO_03990 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
PLHLKKDO_03992 5.33e-39 - - - - - - - -
PLHLKKDO_03993 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
PLHLKKDO_03994 3.78e-74 ydfQ - - CO - - - Thioredoxin
PLHLKKDO_03995 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
PLHLKKDO_03996 9.11e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PLHLKKDO_03997 2.83e-144 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
PLHLKKDO_03998 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PLHLKKDO_03999 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
PLHLKKDO_04000 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
PLHLKKDO_04001 3.8e-223 - - - S - - - Alpha/beta hydrolase family
PLHLKKDO_04003 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
PLHLKKDO_04004 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PLHLKKDO_04005 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PLHLKKDO_04007 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PLHLKKDO_04008 1.56e-156 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PLHLKKDO_04009 4.04e-149 ydfE - - S - - - Flavin reductase like domain
PLHLKKDO_04010 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PLHLKKDO_04011 2.3e-202 - - - EG - - - EamA-like transporter family
PLHLKKDO_04012 1.01e-184 - - - J - - - GNAT acetyltransferase
PLHLKKDO_04013 9.07e-297 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PLHLKKDO_04014 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
PLHLKKDO_04015 2.16e-135 ydeS - - K - - - Transcriptional regulator
PLHLKKDO_04016 2.09e-252 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
PLHLKKDO_04017 7.99e-195 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PLHLKKDO_04018 2.49e-73 - - - K - - - HxlR-like helix-turn-helix
PLHLKKDO_04019 1.39e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
PLHLKKDO_04020 1.06e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
PLHLKKDO_04021 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PLHLKKDO_04022 6.34e-195 ydeK - - EG - - - -transporter
PLHLKKDO_04023 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
PLHLKKDO_04024 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
PLHLKKDO_04025 8.72e-133 - - - - - - - -
PLHLKKDO_04026 2.25e-132 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
PLHLKKDO_04027 9.2e-70 ydeH - - - - - - -
PLHLKKDO_04028 1.88e-277 ydeG - - EGP - - - Major facilitator superfamily
PLHLKKDO_04029 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PLHLKKDO_04030 1.12e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
PLHLKKDO_04031 3.23e-220 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PLHLKKDO_04032 1.31e-210 - - - K - - - AraC-like ligand binding domain
PLHLKKDO_04033 6.87e-182 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PLHLKKDO_04034 1.45e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
PLHLKKDO_04035 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
PLHLKKDO_04036 1.07e-241 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
PLHLKKDO_04037 1.21e-52 - - - - - - - -
PLHLKKDO_04038 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
PLHLKKDO_04039 6.13e-176 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PLHLKKDO_04040 2.85e-58 - - - - - - - -
PLHLKKDO_04041 8.04e-96 - - - J - - - Acetyltransferase (GNAT) domain
PLHLKKDO_04044 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
PLHLKKDO_04045 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
PLHLKKDO_04046 1.04e-122 gerD - - - ko:K06294 - ko00000 -
PLHLKKDO_04047 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PLHLKKDO_04048 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PLHLKKDO_04049 6.98e-89 ybaK - - S - - - Protein of unknown function (DUF2521)
PLHLKKDO_04050 6.15e-186 ybaJ - - Q - - - Methyltransferase domain
PLHLKKDO_04051 2.48e-83 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PLHLKKDO_04052 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PLHLKKDO_04053 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PLHLKKDO_04054 1.87e-176 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PLHLKKDO_04055 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PLHLKKDO_04056 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PLHLKKDO_04057 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
PLHLKKDO_04058 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PLHLKKDO_04059 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PLHLKKDO_04060 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PLHLKKDO_04061 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
PLHLKKDO_04062 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PLHLKKDO_04063 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PLHLKKDO_04064 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PLHLKKDO_04065 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PLHLKKDO_04066 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PLHLKKDO_04067 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
PLHLKKDO_04068 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PLHLKKDO_04069 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PLHLKKDO_04070 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PLHLKKDO_04071 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PLHLKKDO_04072 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PLHLKKDO_04073 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PLHLKKDO_04074 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PLHLKKDO_04075 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PLHLKKDO_04076 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PLHLKKDO_04077 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PLHLKKDO_04078 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PLHLKKDO_04079 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PLHLKKDO_04080 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PLHLKKDO_04081 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PLHLKKDO_04082 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PLHLKKDO_04083 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PLHLKKDO_04084 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PLHLKKDO_04085 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PLHLKKDO_04086 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PLHLKKDO_04087 2.04e-227 ybaC - - S - - - Alpha/beta hydrolase family
PLHLKKDO_04088 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PLHLKKDO_04089 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PLHLKKDO_04090 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PLHLKKDO_04091 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PLHLKKDO_04092 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
PLHLKKDO_04093 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PLHLKKDO_04094 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PLHLKKDO_04095 2.08e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
PLHLKKDO_04096 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PLHLKKDO_04097 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PLHLKKDO_04098 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PLHLKKDO_04099 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PLHLKKDO_04100 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PLHLKKDO_04101 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PLHLKKDO_04102 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
PLHLKKDO_04103 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
PLHLKKDO_04104 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PLHLKKDO_04105 1.68e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PLHLKKDO_04106 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PLHLKKDO_04107 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
PLHLKKDO_04108 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PLHLKKDO_04109 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PLHLKKDO_04110 7.42e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PLHLKKDO_04111 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
PLHLKKDO_04112 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PLHLKKDO_04113 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PLHLKKDO_04114 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
PLHLKKDO_04115 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PLHLKKDO_04116 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
PLHLKKDO_04117 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
PLHLKKDO_04118 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PLHLKKDO_04119 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PLHLKKDO_04120 1.81e-41 yazB - - K - - - transcriptional
PLHLKKDO_04121 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PLHLKKDO_04122 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PLHLKKDO_04123 3.88e-204 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PLHLKKDO_04124 1.08e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
PLHLKKDO_04125 5.98e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
PLHLKKDO_04126 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PLHLKKDO_04127 1.26e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PLHLKKDO_04128 1.7e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
PLHLKKDO_04129 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PLHLKKDO_04130 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PLHLKKDO_04131 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PLHLKKDO_04132 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
PLHLKKDO_04133 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PLHLKKDO_04134 6.92e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
PLHLKKDO_04135 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PLHLKKDO_04136 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
PLHLKKDO_04139 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PLHLKKDO_04140 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
PLHLKKDO_04141 5.21e-138 yabQ - - S - - - spore cortex biosynthesis protein
PLHLKKDO_04142 1.91e-66 yabP - - S - - - Sporulation protein YabP
PLHLKKDO_04143 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PLHLKKDO_04144 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PLHLKKDO_04145 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PLHLKKDO_04146 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
PLHLKKDO_04147 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PLHLKKDO_04148 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
PLHLKKDO_04149 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PLHLKKDO_04150 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PLHLKKDO_04151 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PLHLKKDO_04152 1.43e-306 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PLHLKKDO_04153 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PLHLKKDO_04154 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
PLHLKKDO_04155 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
PLHLKKDO_04156 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PLHLKKDO_04157 5.32e-53 veg - - S - - - protein conserved in bacteria
PLHLKKDO_04158 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
PLHLKKDO_04159 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PLHLKKDO_04160 1.05e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PLHLKKDO_04161 4.1e-278 yabE - - T - - - protein conserved in bacteria
PLHLKKDO_04162 4.85e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
PLHLKKDO_04163 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PLHLKKDO_04164 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
PLHLKKDO_04165 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PLHLKKDO_04166 5.95e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
PLHLKKDO_04167 1.14e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
PLHLKKDO_04168 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
PLHLKKDO_04169 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
PLHLKKDO_04170 9.28e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PLHLKKDO_04171 1.48e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
PLHLKKDO_04172 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
PLHLKKDO_04173 9.43e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PLHLKKDO_04174 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
PLHLKKDO_04175 1.02e-259 yaaN - - P - - - Belongs to the TelA family
PLHLKKDO_04176 2.7e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PLHLKKDO_04177 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
PLHLKKDO_04178 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
PLHLKKDO_04179 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
PLHLKKDO_04180 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PLHLKKDO_04181 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PLHLKKDO_04182 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PLHLKKDO_04183 3e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PLHLKKDO_04184 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
PLHLKKDO_04185 3.65e-276 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
PLHLKKDO_04186 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
PLHLKKDO_04187 1.52e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
PLHLKKDO_04189 3.98e-295 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PLHLKKDO_04190 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PLHLKKDO_04191 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PLHLKKDO_04192 5.05e-314 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PLHLKKDO_04193 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PLHLKKDO_04194 2.6e-233 yaaC - - S - - - YaaC-like Protein
PLHLKKDO_04195 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)