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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CMMIBCOG_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMMIBCOG_00002	1.88e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMMIBCOG_00003	2.23e-298	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMMIBCOG_00004	1.01e-115	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
CMMIBCOG_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMMIBCOG_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMMIBCOG_00007	5.13e-106	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
CMMIBCOG_00008	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
CMMIBCOG_00009	2.21e-97	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CMMIBCOG_00013	9.19e-86	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
CMMIBCOG_00014	1.15e-239	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CMMIBCOG_00015	6.78e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
CMMIBCOG_00016	2.88e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
CMMIBCOG_00017	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CMMIBCOG_00018	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CMMIBCOG_00019	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMMIBCOG_00020	2.64e-262	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CMMIBCOG_00021	1.49e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
CMMIBCOG_00022	1.1e-82	-	-	-	I	-	-	-	Sterol carrier protein
CMMIBCOG_00023	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CMMIBCOG_00024	3.8e-47	-	-	-	-	-	-	-	-
CMMIBCOG_00025	4.49e-188	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
CMMIBCOG_00026	1.73e-303	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
CMMIBCOG_00027	9.26e-90	crgA	-	-	D	-	-	-	Involved in cell division
CMMIBCOG_00028	1.12e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
CMMIBCOG_00029	3.33e-267	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CMMIBCOG_00030	3.3e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
CMMIBCOG_00031	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
CMMIBCOG_00032	4.29e-227	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
CMMIBCOG_00033	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
CMMIBCOG_00034	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CMMIBCOG_00035	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
CMMIBCOG_00036	1.57e-108	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
CMMIBCOG_00037	2.6e-168	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
CMMIBCOG_00038	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
CMMIBCOG_00039	1.02e-282	-	-	-	T	-	-	-	Histidine kinase
CMMIBCOG_00040	2.69e-146	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CMMIBCOG_00041	1.11e-244	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
CMMIBCOG_00042	4.32e-213	-	-	-	EG	-	-	-	EamA-like transporter family
CMMIBCOG_00044	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CMMIBCOG_00045	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
CMMIBCOG_00046	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
CMMIBCOG_00047	1.58e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
CMMIBCOG_00048	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
CMMIBCOG_00049	2.94e-242	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
CMMIBCOG_00051	6.21e-88	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMMIBCOG_00052	4.06e-218	-	-	-	EG	-	-	-	EamA-like transporter family
CMMIBCOG_00053	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CMMIBCOG_00054	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CMMIBCOG_00055	2.14e-262	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
CMMIBCOG_00056	1.49e-312	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMMIBCOG_00057	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
CMMIBCOG_00058	7.39e-111	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMMIBCOG_00059	4.34e-66	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMMIBCOG_00060	6.67e-241	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CMMIBCOG_00061	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
CMMIBCOG_00062	2.21e-147	-	-	-	S	-	-	-	Protein of unknown function, DUF624
CMMIBCOG_00063	0.0	-	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
CMMIBCOG_00064	8.71e-296	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_00065	5.08e-209	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00066	1.74e-191	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00067	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
CMMIBCOG_00068	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
CMMIBCOG_00069	2.65e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CMMIBCOG_00070	1.02e-257	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CMMIBCOG_00071	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
CMMIBCOG_00072	7e-54	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
CMMIBCOG_00073	3.44e-239	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMMIBCOG_00074	4.62e-15	-	-	-	S	-	-	-	Protein of unknown function, DUF624
CMMIBCOG_00075	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
CMMIBCOG_00076	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CMMIBCOG_00077	3.48e-310	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
CMMIBCOG_00078	2.32e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00079	7.49e-234	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CMMIBCOG_00080	0.0	-	-	-	M	-	-	-	domain protein
CMMIBCOG_00081	4.02e-277	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
CMMIBCOG_00082	6.5e-115	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00083	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CMMIBCOG_00084	1.79e-214	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CMMIBCOG_00085	1.06e-168	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
CMMIBCOG_00086	6.92e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
CMMIBCOG_00087	7.76e-231	-	-	-	C	-	-	-	Aldo/keto reductase family
CMMIBCOG_00088	3.21e-75	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CMMIBCOG_00089	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CMMIBCOG_00090	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
CMMIBCOG_00091	2.72e-147	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMMIBCOG_00092	9.49e-302	-	-	-	G	-	-	-	MFS/sugar transport protein
CMMIBCOG_00093	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
CMMIBCOG_00094	1.21e-136	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
CMMIBCOG_00095	6.58e-293	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
CMMIBCOG_00096	2.53e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CMMIBCOG_00098	1.91e-267	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CMMIBCOG_00099	1.14e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMMIBCOG_00100	4.79e-103	-	-	-	S	-	-	-	FMN_bind
CMMIBCOG_00101	6.93e-116	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00102	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CMMIBCOG_00103	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CMMIBCOG_00104	4.95e-288	-	-	-	S	-	-	-	Putative ABC-transporter type IV
CMMIBCOG_00105	2.38e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CMMIBCOG_00108	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
CMMIBCOG_00109	1.37e-249	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
CMMIBCOG_00110	5.68e-151	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_00111	1.23e-252	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMMIBCOG_00112	1.45e-302	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
CMMIBCOG_00113	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
CMMIBCOG_00114	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
CMMIBCOG_00115	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CMMIBCOG_00116	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
CMMIBCOG_00117	4.83e-177	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
CMMIBCOG_00118	4.06e-42	-	-	-	S	-	-	-	granule-associated protein
CMMIBCOG_00119	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
CMMIBCOG_00120	1.31e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
CMMIBCOG_00121	4.39e-315	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_00123	5.95e-214	-	-	-	P	ko:K02025,ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00124	1.61e-185	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00125	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
CMMIBCOG_00126	0.0	-	3.2.1.187	GH121	DG	ko:K18206	-	ko00000,ko01000	Bacterial Ig-like domain (group 4)
CMMIBCOG_00127	0.0	-	-	-	G	-	-	-	Bacterial Ig-like domain (group 4)
CMMIBCOG_00128	1.14e-263	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
CMMIBCOG_00129	1.64e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMMIBCOG_00130	8.12e-134	-	-	-	-	-	-	-	-
CMMIBCOG_00131	1.08e-287	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
CMMIBCOG_00132	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CMMIBCOG_00134	1.24e-181	-	-	-	D	-	-	-	bacterial-type flagellum organization
CMMIBCOG_00135	1.46e-237	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
CMMIBCOG_00136	1.5e-162	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
CMMIBCOG_00137	1.4e-117	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
CMMIBCOG_00138	3.15e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
CMMIBCOG_00139	1.8e-79	-	-	-	U	-	-	-	TadE-like protein
CMMIBCOG_00140	6.79e-73	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
CMMIBCOG_00141	9.99e-273	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
CMMIBCOG_00142	6.51e-249	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CMMIBCOG_00143	1.57e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_00144	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
CMMIBCOG_00145	3.71e-135	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMMIBCOG_00146	7.1e-175	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
CMMIBCOG_00147	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
CMMIBCOG_00148	5.73e-264	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMMIBCOG_00149	8.81e-148	-	-	-	-	-	-	-	-
CMMIBCOG_00150	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CMMIBCOG_00151	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CMMIBCOG_00152	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
CMMIBCOG_00153	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
CMMIBCOG_00154	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
CMMIBCOG_00155	1.09e-249	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMMIBCOG_00156	1.24e-263	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
CMMIBCOG_00157	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_00158	1.98e-213	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00159	5.47e-211	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00160	4.6e-234	-	-	-	G	-	-	-	beta-fructofuranosidase activity
CMMIBCOG_00161	1.11e-130	-	-	-	S	-	-	-	Protein of unknown function, DUF624
CMMIBCOG_00162	2.13e-68	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
CMMIBCOG_00163	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
CMMIBCOG_00164	1.1e-276	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Myo-inositol-1-phosphate synthase
CMMIBCOG_00165	2.8e-301	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
CMMIBCOG_00166	3.6e-244	-	-	-	I	-	-	-	PAP2 superfamily
CMMIBCOG_00167	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMMIBCOG_00168	1.89e-148	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMMIBCOG_00169	2.05e-258	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CMMIBCOG_00170	8.76e-238	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CMMIBCOG_00171	6.22e-52	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
CMMIBCOG_00172	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMMIBCOG_00173	5.02e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CMMIBCOG_00174	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
CMMIBCOG_00175	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
CMMIBCOG_00176	2.72e-82	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
CMMIBCOG_00177	7.75e-126	-	-	-	S	-	-	-	GtrA-like protein
CMMIBCOG_00178	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMMIBCOG_00179	1.24e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
CMMIBCOG_00180	1.86e-242	-	-	-	-	-	-	-	-
CMMIBCOG_00181	1.63e-189	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
CMMIBCOG_00182	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMMIBCOG_00185	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CMMIBCOG_00186	4.48e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
CMMIBCOG_00187	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CMMIBCOG_00188	2.1e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CMMIBCOG_00189	6.6e-259	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
CMMIBCOG_00190	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMMIBCOG_00191	7.29e-224	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
CMMIBCOG_00192	1.31e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
CMMIBCOG_00193	5.23e-277	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CMMIBCOG_00194	3.99e-278	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_00195	1.68e-205	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00196	1.12e-188	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00197	4.12e-274	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CMMIBCOG_00198	4.81e-235	-	-	-	S	-	-	-	CAAX protease self-immunity
CMMIBCOG_00199	1.96e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
CMMIBCOG_00200	5.84e-293	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00201	2.18e-289	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00202	2.71e-160	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_00203	1.13e-293	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00204	2.8e-107	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
CMMIBCOG_00205	2.76e-163	gntR	-	-	K	-	-	-	FCD
CMMIBCOG_00206	2.35e-304	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
CMMIBCOG_00207	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00208	1.82e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
CMMIBCOG_00209	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
CMMIBCOG_00210	1.52e-136	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
CMMIBCOG_00211	4.14e-199	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CMMIBCOG_00212	2.18e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMMIBCOG_00213	5.05e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
CMMIBCOG_00214	7.94e-83	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CMMIBCOG_00215	3.03e-233	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
CMMIBCOG_00216	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMMIBCOG_00217	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CMMIBCOG_00218	3.99e-194	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
CMMIBCOG_00219	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
CMMIBCOG_00220	8.37e-126	-	-	-	-	-	-	-	-
CMMIBCOG_00221	1.54e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
CMMIBCOG_00222	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
CMMIBCOG_00223	8.48e-178	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMMIBCOG_00224	8.1e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
CMMIBCOG_00225	1.52e-149	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
CMMIBCOG_00226	5.15e-172	-	-	-	-	-	-	-	-
CMMIBCOG_00227	6.03e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMMIBCOG_00228	4.15e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
CMMIBCOG_00229	6.57e-247	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
CMMIBCOG_00230	6.07e-102	-	-	-	K	-	-	-	MerR, DNA binding
CMMIBCOG_00231	1.02e-155	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMMIBCOG_00232	1.18e-178	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CMMIBCOG_00233	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMMIBCOG_00234	3.58e-301	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00235	6.37e-296	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00238	2.98e-224	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
CMMIBCOG_00239	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CMMIBCOG_00240	4.78e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMMIBCOG_00241	1.15e-157	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CMMIBCOG_00242	9.59e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMMIBCOG_00243	3.95e-166	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00244	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
CMMIBCOG_00245	3.73e-212	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
CMMIBCOG_00246	6.81e-293	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
CMMIBCOG_00247	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
CMMIBCOG_00248	1.19e-61	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CMMIBCOG_00249	3.53e-52	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
CMMIBCOG_00250	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMMIBCOG_00251	1.07e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CMMIBCOG_00252	1.62e-294	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
CMMIBCOG_00254	3.48e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CMMIBCOG_00255	3.23e-177	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CMMIBCOG_00256	5.21e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMMIBCOG_00257	1.18e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMMIBCOG_00258	4.85e-185	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
CMMIBCOG_00259	0.0	-	-	-	-	-	-	-	-
CMMIBCOG_00260	6.21e-207	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
CMMIBCOG_00261	9.8e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CMMIBCOG_00262	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
CMMIBCOG_00263	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
CMMIBCOG_00264	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
CMMIBCOG_00265	1.77e-107	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMMIBCOG_00266	0.0	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
CMMIBCOG_00268	1.89e-151	-	-	-	-	-	-	-	-
CMMIBCOG_00269	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMMIBCOG_00270	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CMMIBCOG_00271	8.51e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
CMMIBCOG_00272	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CMMIBCOG_00273	1.53e-217	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
CMMIBCOG_00274	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
CMMIBCOG_00275	4e-235	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
CMMIBCOG_00276	7.53e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CMMIBCOG_00277	8.36e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CMMIBCOG_00278	2.17e-146	-	-	-	D	-	-	-	nuclear chromosome segregation
CMMIBCOG_00279	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CMMIBCOG_00280	2.1e-268	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CMMIBCOG_00281	1.44e-281	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CMMIBCOG_00282	1.22e-157	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMMIBCOG_00283	1.61e-277	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
CMMIBCOG_00284	2.31e-166	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
CMMIBCOG_00285	1.75e-255	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
CMMIBCOG_00286	1.5e-208	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CMMIBCOG_00287	1.92e-218	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
CMMIBCOG_00288	6.41e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMMIBCOG_00289	9.44e-186	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
CMMIBCOG_00290	2.72e-314	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
CMMIBCOG_00291	5.91e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMMIBCOG_00292	5.66e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMMIBCOG_00293	2.65e-232	-	-	-	T	-	-	-	Forkhead associated domain
CMMIBCOG_00294	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
CMMIBCOG_00295	2.9e-49	-	-	-	-	-	-	-	-
CMMIBCOG_00296	2.61e-117	-	-	-	NO	-	-	-	SAF
CMMIBCOG_00297	2.78e-41	-	-	-	S	-	-	-	Putative regulatory protein
CMMIBCOG_00298	4.38e-129	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
CMMIBCOG_00299	7.21e-145	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CMMIBCOG_00300	4.21e-215	-	-	-	-	-	-	-	-
CMMIBCOG_00301	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMMIBCOG_00305	7.79e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
CMMIBCOG_00306	1.73e-269	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CMMIBCOG_00307	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
CMMIBCOG_00308	2.61e-78	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
CMMIBCOG_00309	2.09e-267	dapC	-	-	E	-	-	-	Aminotransferase class I and II
CMMIBCOG_00311	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CMMIBCOG_00312	2.8e-231	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00313	3.26e-179	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00314	1.45e-198	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
CMMIBCOG_00315	1.05e-194	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMMIBCOG_00316	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
CMMIBCOG_00317	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00318	3.77e-297	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
CMMIBCOG_00319	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
CMMIBCOG_00320	0.0	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
CMMIBCOG_00322	6.16e-283	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMMIBCOG_00323	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
CMMIBCOG_00324	3.87e-237	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMMIBCOG_00325	1.63e-146	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
CMMIBCOG_00326	3e-158	-	-	-	-	-	-	-	-
CMMIBCOG_00327	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
CMMIBCOG_00328	2.26e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMMIBCOG_00329	1.21e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CMMIBCOG_00330	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
CMMIBCOG_00331	2.55e-100	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMMIBCOG_00332	1.93e-273	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
CMMIBCOG_00333	9.26e-300	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMMIBCOG_00334	5.19e-251	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
CMMIBCOG_00335	8.4e-234	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CMMIBCOG_00336	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CMMIBCOG_00337	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CMMIBCOG_00338	1.64e-151	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMMIBCOG_00339	3.02e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CMMIBCOG_00340	8.86e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMMIBCOG_00341	2.71e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMMIBCOG_00342	3.44e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMMIBCOG_00343	5.42e-75	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMMIBCOG_00344	2.74e-147	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMMIBCOG_00345	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMMIBCOG_00346	1.37e-50	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CMMIBCOG_00347	5.52e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMMIBCOG_00348	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMMIBCOG_00349	1.81e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMMIBCOG_00350	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMMIBCOG_00351	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMMIBCOG_00352	3.93e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMMIBCOG_00353	5.66e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMMIBCOG_00354	1.86e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMMIBCOG_00355	5.14e-130	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMMIBCOG_00356	1.24e-35	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
CMMIBCOG_00357	4.21e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
CMMIBCOG_00358	7.19e-315	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMMIBCOG_00359	1.05e-127	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMMIBCOG_00360	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMMIBCOG_00361	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
CMMIBCOG_00362	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMMIBCOG_00363	1.48e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMMIBCOG_00364	6.43e-238	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMMIBCOG_00365	1.21e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CMMIBCOG_00366	3.16e-233	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMMIBCOG_00368	1.14e-106	-	-	-	-	-	-	-	-
CMMIBCOG_00369	4.21e-243	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CMMIBCOG_00370	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMMIBCOG_00371	1.9e-98	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMMIBCOG_00372	4.09e-240	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMMIBCOG_00373	4.81e-276	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
CMMIBCOG_00374	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMMIBCOG_00375	2.31e-140	-	-	-	-	-	-	-	-
CMMIBCOG_00376	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
CMMIBCOG_00377	3.43e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMMIBCOG_00378	1.88e-279	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMMIBCOG_00379	0.0	-	-	-	T	-	-	-	GHKL domain
CMMIBCOG_00380	2.94e-195	-	-	-	T	-	-	-	LytTr DNA-binding domain
CMMIBCOG_00381	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
CMMIBCOG_00382	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
CMMIBCOG_00383	3.44e-204	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
CMMIBCOG_00384	8.45e-264	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CMMIBCOG_00385	4.35e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMMIBCOG_00387	2.38e-239	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
CMMIBCOG_00388	1.44e-230	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
CMMIBCOG_00389	0.0	-	-	-	U	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
CMMIBCOG_00390	8.95e-129	-	-	-	Q	-	-	-	Isochorismatase family
CMMIBCOG_00391	1.04e-271	-	-	-	S	-	-	-	Choline/ethanolamine kinase
CMMIBCOG_00392	0.0	-	-	-	E	ko:K16238	-	ko00000,ko02000	Amino acid permease
CMMIBCOG_00393	0.0	-	-	-	H	-	-	-	Aminotransferase class-III
CMMIBCOG_00394	1.32e-178	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
CMMIBCOG_00395	2.9e-157	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CMMIBCOG_00396	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
CMMIBCOG_00397	2.28e-194	pspC	-	-	KT	-	-	-	PspC domain
CMMIBCOG_00398	2e-123	-	-	-	-	-	-	-	-
CMMIBCOG_00399	9.07e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
CMMIBCOG_00400	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
CMMIBCOG_00401	3.78e-271	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
CMMIBCOG_00403	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CMMIBCOG_00404	8.47e-264	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
CMMIBCOG_00405	1.83e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMMIBCOG_00406	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
CMMIBCOG_00407	8.62e-133	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
CMMIBCOG_00408	9.07e-275	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
CMMIBCOG_00409	3.36e-55	-	-	-	-	-	-	-	-
CMMIBCOG_00410	5.66e-279	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CMMIBCOG_00411	1.71e-212	-	-	-	S	-	-	-	CHAP domain
CMMIBCOG_00412	2.57e-118	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
CMMIBCOG_00413	1.49e-241	-	-	-	T	-	-	-	Universal stress protein family
CMMIBCOG_00414	9.14e-96	-	-	-	O	-	-	-	OsmC-like protein
CMMIBCOG_00415	4.15e-233	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMMIBCOG_00416	1.71e-166	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
CMMIBCOG_00417	1.79e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
CMMIBCOG_00419	1.49e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CMMIBCOG_00420	7.01e-213	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMMIBCOG_00424	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
CMMIBCOG_00425	9.34e-201	-	-	-	-	-	-	-	-
CMMIBCOG_00426	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
CMMIBCOG_00427	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
CMMIBCOG_00428	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
CMMIBCOG_00429	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
CMMIBCOG_00430	5.75e-205	-	-	-	P	-	-	-	VTC domain
CMMIBCOG_00431	2.54e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
CMMIBCOG_00432	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
CMMIBCOG_00433	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
CMMIBCOG_00434	3.15e-230	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CMMIBCOG_00435	0.0	-	-	-	S	-	-	-	AI-2E family transporter
CMMIBCOG_00436	2.68e-293	-	-	-	M	-	-	-	Glycosyl transferase family 21
CMMIBCOG_00437	9.63e-297	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
CMMIBCOG_00438	8.02e-255	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMMIBCOG_00439	1.72e-128	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CMMIBCOG_00440	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMMIBCOG_00441	2.51e-150	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
CMMIBCOG_00442	2.05e-198	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CMMIBCOG_00443	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CMMIBCOG_00444	5.18e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
CMMIBCOG_00445	1.86e-210	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
CMMIBCOG_00446	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
CMMIBCOG_00447	1.9e-231	-	-	-	V	-	-	-	Beta-lactamase
CMMIBCOG_00448	8.35e-94	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
CMMIBCOG_00449	1.26e-132	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
CMMIBCOG_00450	1.36e-67	-	-	-	G	ko:K17326	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
CMMIBCOG_00451	6.86e-213	-	-	-	G	ko:K17326	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
CMMIBCOG_00452	5.81e-222	-	-	-	U	ko:K17327	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00453	5.39e-192	-	-	-	G	ko:K17328	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00454	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00455	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
CMMIBCOG_00456	0.0	-	-	-	O	-	-	-	Highly conserved protein containing a thioredoxin domain
CMMIBCOG_00457	8.21e-295	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
CMMIBCOG_00458	0.0	-	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolase family 10
CMMIBCOG_00459	8.53e-69	-	-	-	L	-	-	-	Integrase core domain
CMMIBCOG_00460	1.56e-226	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
CMMIBCOG_00461	2.4e-271	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
CMMIBCOG_00462	1.37e-215	-	-	-	F	-	-	-	Inosine-uridine preferring nucleoside hydrolase
CMMIBCOG_00463	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
CMMIBCOG_00464	2.55e-287	xylR	-	-	GK	-	-	-	ROK family
CMMIBCOG_00465	6.81e-126	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CMMIBCOG_00466	3.02e-102	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
CMMIBCOG_00467	2.48e-138	-	-	-	S	ko:K07149	-	ko00000	Membrane
CMMIBCOG_00468	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
CMMIBCOG_00469	2.8e-316	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
CMMIBCOG_00470	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
CMMIBCOG_00471	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
CMMIBCOG_00472	2.4e-232	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
CMMIBCOG_00473	3.24e-293	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
CMMIBCOG_00474	1.81e-231	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00475	5.86e-200	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00476	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
CMMIBCOG_00477	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
CMMIBCOG_00478	2.08e-143	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
CMMIBCOG_00479	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
CMMIBCOG_00480	5.14e-287	xylR	-	-	GK	-	-	-	ROK family
CMMIBCOG_00482	2.63e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
CMMIBCOG_00483	4.95e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMMIBCOG_00484	3.12e-221	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMMIBCOG_00485	6.78e-279	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
CMMIBCOG_00486	8.89e-199	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CMMIBCOG_00487	3.09e-249	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CMMIBCOG_00488	4.85e-192	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
CMMIBCOG_00489	8.3e-160	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00490	2.44e-147	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
CMMIBCOG_00491	1.27e-253	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
CMMIBCOG_00492	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CMMIBCOG_00493	2.33e-157	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CMMIBCOG_00494	2.61e-210	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMMIBCOG_00495	0.0	-	-	-	L	-	-	-	PIF1-like helicase
CMMIBCOG_00496	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMMIBCOG_00497	1.03e-127	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
CMMIBCOG_00498	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
CMMIBCOG_00499	5.71e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
CMMIBCOG_00500	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
CMMIBCOG_00501	9.11e-216	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
CMMIBCOG_00502	5.2e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMMIBCOG_00503	2.95e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMMIBCOG_00504	4.32e-241	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
CMMIBCOG_00505	7.75e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
CMMIBCOG_00506	9.94e-229	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
CMMIBCOG_00507	5e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CMMIBCOG_00508	8.68e-207	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
CMMIBCOG_00509	7.62e-206	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
CMMIBCOG_00510	1.13e-202	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
CMMIBCOG_00511	1.26e-221	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00512	5.24e-187	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00513	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMMIBCOG_00514	1.2e-185	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
CMMIBCOG_00515	3.12e-290	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CMMIBCOG_00516	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00517	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_00518	8.78e-157	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
CMMIBCOG_00519	8.45e-184	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
CMMIBCOG_00520	3.81e-107	-	-	-	S	-	-	-	SnoaL-like domain
CMMIBCOG_00521	2.71e-185	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CMMIBCOG_00522	2.4e-308	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMMIBCOG_00523	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CMMIBCOG_00524	8.06e-213	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00525	1.09e-200	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00526	3.37e-177	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
CMMIBCOG_00527	1.46e-177	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00528	2.45e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
CMMIBCOG_00529	4.68e-280	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
CMMIBCOG_00530	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00531	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CMMIBCOG_00532	1.29e-117	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMMIBCOG_00533	4.58e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMMIBCOG_00534	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
CMMIBCOG_00535	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMMIBCOG_00536	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMMIBCOG_00537	1.5e-276	-	-	-	P	-	-	-	Citrate transporter
CMMIBCOG_00539	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
CMMIBCOG_00543	3.74e-148	-	-	-	K	-	-	-	acetyltransferase
CMMIBCOG_00544	1.13e-140	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00545	3.03e-157	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00546	2.49e-194	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
CMMIBCOG_00547	2.05e-203	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
CMMIBCOG_00548	3.63e-257	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CMMIBCOG_00549	7.46e-201	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
CMMIBCOG_00550	7.88e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMMIBCOG_00551	4.35e-134	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
CMMIBCOG_00552	3.87e-283	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
CMMIBCOG_00553	1.8e-97	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
CMMIBCOG_00554	9.91e-22	-	-	-	P	-	-	-	Belongs to the ABC transporter superfamily
CMMIBCOG_00555	7.85e-59	-	-	-	O	-	-	-	Glutaredoxin
CMMIBCOG_00556	1.89e-178	hflK	-	-	O	-	-	-	prohibitin homologues
CMMIBCOG_00557	8.71e-17	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CMMIBCOG_00558	2.01e-98	-	-	-	-	-	-	-	-
CMMIBCOG_00559	1.97e-172	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00560	1.89e-207	-	-	-	M	-	-	-	Conserved repeat domain
CMMIBCOG_00561	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CMMIBCOG_00562	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMMIBCOG_00563	7.75e-233	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
CMMIBCOG_00564	2.09e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMMIBCOG_00565	2.74e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMMIBCOG_00566	7.41e-117	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
CMMIBCOG_00567	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
CMMIBCOG_00568	1.9e-258	-	2.7.1.83	-	G	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
CMMIBCOG_00569	4.55e-242	yeiI	2.7.1.15, 2.7.1.45, 2.7.1.83	-	G	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
CMMIBCOG_00570	1.06e-165	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
CMMIBCOG_00571	4.27e-273	-	-	-	C	ko:K19954	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
CMMIBCOG_00572	8.1e-236	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
CMMIBCOG_00573	5.47e-314	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMMIBCOG_00574	8.42e-299	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
CMMIBCOG_00575	1.07e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CMMIBCOG_00576	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMMIBCOG_00577	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
CMMIBCOG_00578	3.2e-49	-	-	-	-	-	-	-	-
CMMIBCOG_00579	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
CMMIBCOG_00580	1.97e-175	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
CMMIBCOG_00581	7.98e-294	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CMMIBCOG_00582	2.64e-289	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
CMMIBCOG_00583	8.99e-254	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
CMMIBCOG_00585	5.25e-241	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
CMMIBCOG_00587	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMMIBCOG_00588	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMMIBCOG_00589	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMMIBCOG_00590	2.12e-295	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMMIBCOG_00591	2.2e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMMIBCOG_00592	1.21e-98	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMMIBCOG_00593	2.95e-305	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
CMMIBCOG_00594	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CMMIBCOG_00595	1.42e-218	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CMMIBCOG_00596	8.88e-138	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CMMIBCOG_00598	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
CMMIBCOG_00599	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CMMIBCOG_00600	7.42e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMMIBCOG_00601	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMMIBCOG_00602	1.23e-172	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CMMIBCOG_00603	3.54e-229	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMMIBCOG_00604	1.29e-158	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
CMMIBCOG_00605	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
CMMIBCOG_00606	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
CMMIBCOG_00607	8.18e-206	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
CMMIBCOG_00608	5.14e-34	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
CMMIBCOG_00609	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CMMIBCOG_00610	7.66e-181	-	-	-	C	-	-	-	FMN binding
CMMIBCOG_00611	1.11e-77	-	-	-	-	-	-	-	-
CMMIBCOG_00612	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
CMMIBCOG_00613	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
CMMIBCOG_00614	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
CMMIBCOG_00616	0.0	-	-	-	S	-	-	-	PGAP1-like protein
CMMIBCOG_00617	2.86e-103	-	-	-	-	-	-	-	-
CMMIBCOG_00618	5.88e-233	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
CMMIBCOG_00619	5.1e-242	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
CMMIBCOG_00620	1.34e-120	-	-	-	-	-	-	-	-
CMMIBCOG_00621	3.01e-224	-	-	-	S	-	-	-	Protein of unknown function DUF58
CMMIBCOG_00622	1.86e-233	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
CMMIBCOG_00623	9.46e-176	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMMIBCOG_00624	1.2e-117	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
CMMIBCOG_00625	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMMIBCOG_00626	1.74e-38	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
CMMIBCOG_00627	8.75e-169	-	-	-	-	-	-	-	-
CMMIBCOG_00628	3.53e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
CMMIBCOG_00629	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
CMMIBCOG_00630	6.1e-88	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
CMMIBCOG_00631	1.23e-243	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
CMMIBCOG_00632	1.36e-242	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
CMMIBCOG_00633	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
CMMIBCOG_00634	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
CMMIBCOG_00635	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
CMMIBCOG_00636	2.21e-315	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
CMMIBCOG_00637	4.91e-180	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
CMMIBCOG_00638	3.57e-299	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
CMMIBCOG_00639	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
CMMIBCOG_00640	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CMMIBCOG_00641	0.0	glnP	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00642	1.01e-179	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00643	1.57e-176	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
CMMIBCOG_00644	3.59e-196	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
CMMIBCOG_00645	1.04e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00646	4.31e-258	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00647	4.93e-244	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
CMMIBCOG_00648	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
CMMIBCOG_00649	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
CMMIBCOG_00650	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMMIBCOG_00651	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CMMIBCOG_00652	1.25e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMMIBCOG_00653	9.35e-161	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMMIBCOG_00654	5.76e-308	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMMIBCOG_00657	2.92e-315	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CMMIBCOG_00658	1.23e-151	safC	-	-	S	-	-	-	O-methyltransferase
CMMIBCOG_00659	1.18e-226	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
CMMIBCOG_00660	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
CMMIBCOG_00661	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
CMMIBCOG_00662	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
CMMIBCOG_00663	2.25e-109	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
CMMIBCOG_00664	1.06e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
CMMIBCOG_00665	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
CMMIBCOG_00666	1.88e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
CMMIBCOG_00667	0.0	ykoD	-	-	P	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMMIBCOG_00668	1.1e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CMMIBCOG_00669	2.42e-245	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
CMMIBCOG_00670	1.28e-182	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMMIBCOG_00671	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CMMIBCOG_00672	1.74e-168	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CMMIBCOG_00673	0.0	-	-	-	T	-	-	-	Histidine kinase
CMMIBCOG_00674	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
CMMIBCOG_00675	1.32e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMMIBCOG_00676	9.44e-259	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMMIBCOG_00677	2.34e-35	-	-	-	S	-	-	-	Inner membrane component domain
CMMIBCOG_00678	2.7e-17	-	-	-	-	-	-	-	-
CMMIBCOG_00679	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
CMMIBCOG_00680	6.02e-182	-	-	-	-	-	-	-	-
CMMIBCOG_00682	2.18e-228	-	-	-	S	-	-	-	Conserved hypothetical protein 698
CMMIBCOG_00683	5.23e-290	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter family protein
CMMIBCOG_00684	5.61e-223	-	-	-	C	ko:K07138	-	ko00000	Domain of unknown function (DUF362)
CMMIBCOG_00685	4.4e-144	-	-	-	F	-	-	-	uridine kinase
CMMIBCOG_00686	6.77e-118	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CMMIBCOG_00687	7.92e-185	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
CMMIBCOG_00688	8.74e-241	-	-	-	L	-	-	-	Phage integrase family
CMMIBCOG_00689	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
CMMIBCOG_00690	2.63e-168	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction enzyme, S subunit K01154
CMMIBCOG_00691	4.88e-154	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00692	3.3e-94	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00693	6.72e-106	-	-	-	O	ko:K09935	-	ko00000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00694	1.7e-66	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
CMMIBCOG_00695	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CMMIBCOG_00696	1.15e-182	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CMMIBCOG_00697	5.12e-206	-	-	-	G	-	-	-	Phosphoglycerate mutase family
CMMIBCOG_00698	4.09e-290	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
CMMIBCOG_00699	2.2e-163	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
CMMIBCOG_00700	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
CMMIBCOG_00701	8.21e-174	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
CMMIBCOG_00702	2.12e-182	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00703	6.03e-47	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00704	0.0	-	-	-	S	-	-	-	Putative esterase
CMMIBCOG_00705	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
CMMIBCOG_00706	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMMIBCOG_00707	2.06e-189	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMMIBCOG_00708	1.1e-276	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
CMMIBCOG_00709	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMMIBCOG_00710	5.43e-233	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
CMMIBCOG_00711	2.77e-185	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
CMMIBCOG_00712	4.15e-108	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMMIBCOG_00713	2.12e-135	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
CMMIBCOG_00714	3.78e-181	-	-	-	E	-	-	-	AzlC protein
CMMIBCOG_00715	1.96e-71	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
CMMIBCOG_00716	0.0	cstA	-	-	T	ko:K06200	-	ko00000	5TM C-terminal transporter carbon starvation CstA
CMMIBCOG_00717	1.2e-53	-	-	-	S	-	-	-	Selenoprotein, putative
CMMIBCOG_00718	2.63e-228	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
CMMIBCOG_00719	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
CMMIBCOG_00720	5.84e-134	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
CMMIBCOG_00721	1.42e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMMIBCOG_00722	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMMIBCOG_00723	7.13e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMMIBCOG_00724	4.86e-97	-	-	-	D	-	-	-	Septum formation initiator
CMMIBCOG_00725	1.62e-133	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
CMMIBCOG_00726	4.49e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
CMMIBCOG_00728	9.11e-120	-	-	-	-	-	-	-	-
CMMIBCOG_00729	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
CMMIBCOG_00730	1.12e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
CMMIBCOG_00731	2.04e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMMIBCOG_00732	6.91e-203	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
CMMIBCOG_00733	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
CMMIBCOG_00734	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
CMMIBCOG_00735	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
CMMIBCOG_00736	1.12e-217	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
CMMIBCOG_00738	4.81e-299	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
CMMIBCOG_00739	5.69e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
CMMIBCOG_00740	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
CMMIBCOG_00741	2.18e-289	-	-	-	-	-	-	-	-
CMMIBCOG_00742	6.14e-93	-	-	-	S	-	-	-	Zincin-like metallopeptidase
CMMIBCOG_00743	2.56e-196	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
CMMIBCOG_00744	5.92e-115	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
CMMIBCOG_00745	1.99e-238	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
CMMIBCOG_00746	1.74e-165	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
CMMIBCOG_00747	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMMIBCOG_00748	8.46e-133	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
CMMIBCOG_00749	3.22e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CMMIBCOG_00750	3.19e-179	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
CMMIBCOG_00751	7.98e-205	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00752	3.89e-229	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
CMMIBCOG_00753	9.54e-208	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMMIBCOG_00754	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CMMIBCOG_00755	2.2e-149	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMMIBCOG_00756	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMMIBCOG_00757	2.78e-225	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
CMMIBCOG_00758	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
CMMIBCOG_00760	1.44e-25	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CMMIBCOG_00762	2.38e-246	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
CMMIBCOG_00763	3.03e-147	ehuA	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00764	7.84e-159	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
CMMIBCOG_00765	2.6e-131	tcyA/tcyB	-	-	E	ko:K02029,ko:K02030,ko:K02424,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_00766	1.68e-44	-	-	-	F	-	-	-	DNA helicase
CMMIBCOG_00767	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CMMIBCOG_00768	1.16e-308	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
CMMIBCOG_00769	1.9e-45	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
CMMIBCOG_00770	1.38e-66	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	COG0732 Restriction endonuclease S subunits
CMMIBCOG_00771	1.2e-133	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMMIBCOG_00772	9.81e-38	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
CMMIBCOG_00773	1.33e-211	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
CMMIBCOG_00774	8.64e-156	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
CMMIBCOG_00775	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMMIBCOG_00776	6.46e-211	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
CMMIBCOG_00777	1.75e-149	-	-	-	L	-	-	-	NUDIX domain
CMMIBCOG_00778	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
CMMIBCOG_00779	1.18e-271	-	-	-	-	-	-	-	-
CMMIBCOG_00781	8.33e-171	-	-	-	L	-	-	-	Phage integrase family
CMMIBCOG_00782	5.98e-91	-	-	-	-	-	-	-	-
CMMIBCOG_00783	1.4e-18	-	-	-	-	-	-	-	-
CMMIBCOG_00784	1.66e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
CMMIBCOG_00785	2.91e-19	-	-	-	-	-	-	-	-
CMMIBCOG_00787	3.04e-98	-	-	-	-	-	-	-	-
CMMIBCOG_00789	1.76e-27	-	-	-	-	-	-	-	-
CMMIBCOG_00794	1.94e-83	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	single-stranded DNA-binding protein
CMMIBCOG_00795	7.38e-61	-	-	-	-	-	-	-	-
CMMIBCOG_00797	1.08e-224	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
CMMIBCOG_00799	4.96e-64	-	-	-	V	-	-	-	HNH endonuclease
CMMIBCOG_00800	2.37e-31	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CMMIBCOG_00809	7.94e-61	-	-	-	-	-	-	-	-
CMMIBCOG_00812	7.5e-25	-	-	-	K	-	-	-	Helix-turn-helix domain
CMMIBCOG_00813	4.14e-197	-	-	-	J	-	-	-	tRNA 5'-leader removal
CMMIBCOG_00814	8.04e-70	-	-	-	V	-	-	-	HNH nucleases
CMMIBCOG_00815	5.93e-16	-	-	-	S	-	-	-	HNH endonuclease
CMMIBCOG_00816	1.32e-39	-	-	-	-	-	-	-	-
CMMIBCOG_00817	2.02e-285	-	-	-	S	-	-	-	Terminase
CMMIBCOG_00818	1.28e-231	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
CMMIBCOG_00819	9.04e-119	-	-	-	-	-	-	-	-
CMMIBCOG_00821	3.78e-30	-	-	-	-	-	-	-	-
CMMIBCOG_00822	1.47e-159	-	-	-	S	-	-	-	Phage capsid family
CMMIBCOG_00823	4.25e-85	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
CMMIBCOG_00824	1.64e-59	-	-	-	-	-	-	-	-
CMMIBCOG_00825	1.45e-42	-	-	-	-	-	-	-	-
CMMIBCOG_00826	1.87e-79	-	-	-	-	-	-	-	-
CMMIBCOG_00827	1.29e-140	-	-	-	-	-	-	-	-
CMMIBCOG_00828	2.15e-82	-	-	-	-	-	-	-	-
CMMIBCOG_00830	3.19e-202	-	-	-	S	-	-	-	phage tail tape measure protein
CMMIBCOG_00831	5e-147	-	-	-	-	-	-	-	-
CMMIBCOG_00832	6.81e-142	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CMMIBCOG_00836	2.5e-86	-	-	-	-	-	-	-	-
CMMIBCOG_00838	1.23e-41	-	-	-	-	-	-	-	-
CMMIBCOG_00839	6.17e-28	-	-	-	-	-	-	-	-
CMMIBCOG_00840	2.56e-191	-	-	-	L	-	-	-	DNA integration
CMMIBCOG_00841	1.62e-23	-	-	-	-	-	-	-	-
CMMIBCOG_00842	6.82e-245	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CMMIBCOG_00843	3.62e-39	-	-	-	S	-	-	-	Putative phage holin Dp-1
CMMIBCOG_00844	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CMMIBCOG_00846	5.33e-92	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMMIBCOG_00847	3.28e-100	-	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CMMIBCOG_00848	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CMMIBCOG_00849	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
CMMIBCOG_00850	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
CMMIBCOG_00851	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMMIBCOG_00852	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
CMMIBCOG_00853	4.99e-311	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
CMMIBCOG_00854	2.66e-138	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMMIBCOG_00855	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CMMIBCOG_00856	5.35e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
CMMIBCOG_00857	8.69e-277	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CMMIBCOG_00858	2.58e-192	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CMMIBCOG_00859	3.17e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMMIBCOG_00860	1.97e-74	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
CMMIBCOG_00861	9.46e-167	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
CMMIBCOG_00862	8.09e-79	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
CMMIBCOG_00863	6.83e-50	-	-	-	-	-	-	-	-
CMMIBCOG_00864	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMMIBCOG_00865	1.06e-106	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMMIBCOG_00866	2.36e-253	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMMIBCOG_00867	3.69e-95	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
CMMIBCOG_00868	4.7e-282	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CMMIBCOG_00869	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CMMIBCOG_00870	3.9e-105	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
CMMIBCOG_00871	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
CMMIBCOG_00872	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMMIBCOG_00873	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
CMMIBCOG_00874	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
CMMIBCOG_00875	6.13e-299	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
CMMIBCOG_00876	1.14e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
CMMIBCOG_00877	7.57e-304	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CMMIBCOG_00878	6.78e-128	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
CMMIBCOG_00879	1.6e-140	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CMMIBCOG_00880	5.57e-310	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CMMIBCOG_00881	8.29e-206	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
CMMIBCOG_00883	3.98e-187	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CMMIBCOG_00884	1.49e-73	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
CMMIBCOG_00885	2.86e-267	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
CMMIBCOG_00886	1.14e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMMIBCOG_00887	0.0	corC	-	-	S	-	-	-	CBS domain
CMMIBCOG_00888	2.58e-228	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMMIBCOG_00889	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
CMMIBCOG_00890	4.86e-260	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
CMMIBCOG_00891	4.16e-57	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
CMMIBCOG_00892	0.0	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CMMIBCOG_00893	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00895	1.12e-286	-	-	-	G	-	-	-	Transmembrane secretion effector
CMMIBCOG_00896	4.33e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_00897	3.96e-53	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CMMIBCOG_00898	2.67e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
CMMIBCOG_00899	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMMIBCOG_00901	2.96e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMMIBCOG_00902	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CMMIBCOG_00903	3.74e-41	-	-	-	EGP	ko:K08177,ko:K19577	-	ko00000,ko02000	Major facilitator Superfamily
CMMIBCOG_00904	2.36e-34	yhjX	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major facilitator Superfamily
CMMIBCOG_00905	1.08e-249	-	-	-	S	ko:K06889	-	ko00000	alpha beta
CMMIBCOG_00906	1.29e-127	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CMMIBCOG_00907	2.44e-120	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMMIBCOG_00908	1e-76	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMMIBCOG_00909	1.11e-96	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMMIBCOG_00911	8.14e-290	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
CMMIBCOG_00912	3.02e-174	-	-	-	S	-	-	-	UPF0126 domain
CMMIBCOG_00913	7.89e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CMMIBCOG_00914	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMMIBCOG_00915	3.15e-298	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
CMMIBCOG_00916	9.78e-188	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
CMMIBCOG_00917	0.0	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
CMMIBCOG_00918	7.44e-278	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
CMMIBCOG_00919	0.0	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
CMMIBCOG_00920	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
CMMIBCOG_00921	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
CMMIBCOG_00922	3.85e-98	-	-	-	-	-	-	-	-
CMMIBCOG_00923	0.0	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
CMMIBCOG_00924	2.73e-203	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_00925	2.79e-253	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CMMIBCOG_00926	1.67e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
CMMIBCOG_00927	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CMMIBCOG_00928	1.42e-202	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
CMMIBCOG_00929	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
CMMIBCOG_00930	8.48e-241	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CMMIBCOG_00931	1.06e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
CMMIBCOG_00932	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMMIBCOG_00933	1.44e-228	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
CMMIBCOG_00934	5.08e-198	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
CMMIBCOG_00935	8.22e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMMIBCOG_00936	9.36e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMMIBCOG_00937	6.03e-210	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
CMMIBCOG_00938	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CMMIBCOG_00939	9.59e-141	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CMMIBCOG_00940	4.36e-89	arsC	1.20.4.1, 2.8.4.2	-	T	ko:K03741,ko:K18701	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMMIBCOG_00941	9.78e-281	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00942	3.66e-157	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CMMIBCOG_00943	6.64e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMMIBCOG_00944	4.13e-180	-	-	-	S	-	-	-	SdpI/YhfL protein family
CMMIBCOG_00945	3.2e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CMMIBCOG_00946	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMMIBCOG_00947	5.36e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CMMIBCOG_00950	1.81e-81	-	-	-	-	-	-	-	-
CMMIBCOG_00951	9.76e-125	-	-	-	M	-	-	-	Peptidase family M23
CMMIBCOG_00952	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
CMMIBCOG_00953	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
CMMIBCOG_00954	1.58e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
CMMIBCOG_00955	2.74e-266	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
CMMIBCOG_00956	5.78e-139	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
CMMIBCOG_00957	3.58e-93	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CMMIBCOG_00958	2.71e-316	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMMIBCOG_00959	3.94e-88	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMMIBCOG_00960	2.98e-182	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
CMMIBCOG_00961	2.54e-169	-	-	-	-	-	-	-	-
CMMIBCOG_00963	6.91e-298	-	-	-	K	-	-	-	Fic/DOC family
CMMIBCOG_00964	4.75e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
CMMIBCOG_00965	0.0	-	-	-	M	-	-	-	domain protein
CMMIBCOG_00968	1.72e-210	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
CMMIBCOG_00969	1.48e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CMMIBCOG_00970	1.93e-182	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
CMMIBCOG_00971	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CMMIBCOG_00972	4.58e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
CMMIBCOG_00973	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
CMMIBCOG_00974	2.13e-228	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CMMIBCOG_00975	7.17e-119	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
CMMIBCOG_00976	5.66e-189	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
CMMIBCOG_00977	7.04e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
CMMIBCOG_00978	1.13e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMMIBCOG_00980	5.47e-152	yoaP	-	-	E	-	-	-	YoaP-like
CMMIBCOG_00981	7.51e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMMIBCOG_00982	3.51e-154	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CMMIBCOG_00983	2.39e-93	-	-	-	K	-	-	-	MerR family regulatory protein
CMMIBCOG_00984	2.21e-253	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
CMMIBCOG_00985	1.31e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
CMMIBCOG_00986	7.46e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00987	4.38e-71	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CMMIBCOG_00988	3.16e-234	-	-	-	P	-	-	-	Cation efflux family
CMMIBCOG_00991	8.26e-181	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
CMMIBCOG_00992	7.03e-197	-	-	-	-	-	-	-	-
CMMIBCOG_00993	1.75e-182	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
CMMIBCOG_00994	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CMMIBCOG_00995	2.69e-231	-	-	-	S	-	-	-	IMP dehydrogenase activity
CMMIBCOG_00997	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
CMMIBCOG_00998	4.55e-143	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
CMMIBCOG_00999	4.53e-88	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMMIBCOG_01001	2.77e-19	-	-	-	-	-	-	-	-
CMMIBCOG_01002	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01003	2.58e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
CMMIBCOG_01004	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01005	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CMMIBCOG_01006	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMMIBCOG_01007	7.91e-230	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
CMMIBCOG_01008	6.25e-216	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CMMIBCOG_01009	2.1e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CMMIBCOG_01010	1.24e-279	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
CMMIBCOG_01011	3.16e-188	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMMIBCOG_01012	1.74e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
CMMIBCOG_01013	4.39e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMMIBCOG_01014	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
CMMIBCOG_01015	3.3e-260	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CMMIBCOG_01016	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
CMMIBCOG_01017	3.96e-251	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMMIBCOG_01018	4.09e-253	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMMIBCOG_01019	1.44e-202	-	-	-	G	-	-	-	Fructosamine kinase
CMMIBCOG_01020	1.68e-198	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CMMIBCOG_01021	2.51e-161	-	-	-	S	-	-	-	PAC2 family
CMMIBCOG_01024	5e-116	-	-	-	K	-	-	-	Putative zinc ribbon domain
CMMIBCOG_01025	4.89e-159	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
CMMIBCOG_01026	8.8e-37	-	-	-	L	-	-	-	DNA integration
CMMIBCOG_01027	2.55e-79	-	-	-	-	-	-	-	-
CMMIBCOG_01028	6.17e-144	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMMIBCOG_01029	5.45e-99	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
CMMIBCOG_01030	5.93e-43	-	-	-	-	-	-	-	-
CMMIBCOG_01031	6.36e-22	-	-	-	-	-	-	-	-
CMMIBCOG_01037	1.2e-180	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
CMMIBCOG_01038	6.43e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
CMMIBCOG_01039	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
CMMIBCOG_01040	1.79e-71	-	-	-	-	-	-	-	-
CMMIBCOG_01041	0.0	-	-	-	K	-	-	-	WYL domain
CMMIBCOG_01042	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CMMIBCOG_01044	1.56e-93	-	-	-	-	-	-	-	-
CMMIBCOG_01045	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CMMIBCOG_01046	2.81e-183	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CMMIBCOG_01047	8.03e-206	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMMIBCOG_01048	1.69e-48	-	-	-	-	-	-	-	-
CMMIBCOG_01049	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
CMMIBCOG_01050	0.0	-	-	-	-	-	-	-	-
CMMIBCOG_01051	1.1e-205	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CMMIBCOG_01052	5.48e-281	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CMMIBCOG_01053	5.27e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMMIBCOG_01054	3.98e-83	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
CMMIBCOG_01055	3.38e-256	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMMIBCOG_01056	1.34e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMMIBCOG_01057	2.73e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CMMIBCOG_01058	2.38e-172	yebC	-	-	K	-	-	-	transcriptional regulatory protein
CMMIBCOG_01059	2.88e-144	pgsA1	2.7.8.11, 2.7.8.5	-	I	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
CMMIBCOG_01060	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMMIBCOG_01061	3.22e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
CMMIBCOG_01062	2.68e-64	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
CMMIBCOG_01063	2.27e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
CMMIBCOG_01064	8.44e-134	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMMIBCOG_01065	1.24e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
CMMIBCOG_01066	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
CMMIBCOG_01067	2.25e-137	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
CMMIBCOG_01068	4.83e-231	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMMIBCOG_01069	2.25e-207	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CMMIBCOG_01070	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CMMIBCOG_01071	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CMMIBCOG_01072	1.12e-95	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CMMIBCOG_01073	5.63e-178	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CMMIBCOG_01074	1.12e-287	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CMMIBCOG_01075	5.62e-228	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
CMMIBCOG_01076	6.26e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CMMIBCOG_01077	2.04e-172	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CMMIBCOG_01079	6.23e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMMIBCOG_01080	7.95e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CMMIBCOG_01081	1.49e-108	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMMIBCOG_01082	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
CMMIBCOG_01083	2.51e-157	-	-	-	-	-	-	-	-
CMMIBCOG_01085	1.67e-241	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMMIBCOG_01086	1.1e-180	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMMIBCOG_01087	5.54e-131	-	-	-	-	-	-	-	-
CMMIBCOG_01088	5.01e-311	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CMMIBCOG_01089	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMMIBCOG_01090	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
CMMIBCOG_01091	4.16e-297	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
CMMIBCOG_01092	1.33e-139	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
CMMIBCOG_01093	9.7e-223	-	-	-	G	-	-	-	Fic/DOC family
CMMIBCOG_01094	1.77e-186	-	-	-	-	-	-	-	-
CMMIBCOG_01095	2.01e-208	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
CMMIBCOG_01096	5.35e-216	-	-	-	S	-	-	-	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CMMIBCOG_01097	1.32e-99	-	3.4.13.22	-	S	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CMMIBCOG_01098	2.81e-123	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
CMMIBCOG_01099	5.7e-06	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
CMMIBCOG_01100	1.48e-122	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
CMMIBCOG_01101	0.0	-	-	-	S	-	-	-	Histidine phosphatase superfamily (branch 2)
CMMIBCOG_01102	1.95e-60	-	-	-	L	-	-	-	transposition
CMMIBCOG_01103	8.53e-30	-	-	-	C	-	-	-	Acetamidase/Formamidase family
CMMIBCOG_01104	5.29e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
CMMIBCOG_01105	2.89e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_01106	5.59e-160	-	-	-	S	-	-	-	ABC-2 family transporter protein
CMMIBCOG_01107	1.24e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CMMIBCOG_01108	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CMMIBCOG_01109	4.06e-241	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMMIBCOG_01110	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
CMMIBCOG_01111	1.25e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
CMMIBCOG_01112	4.79e-173	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
CMMIBCOG_01113	2.65e-246	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
CMMIBCOG_01114	2.38e-218	-	-	-	L	-	-	-	Tetratricopeptide repeat
CMMIBCOG_01115	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMMIBCOG_01116	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
CMMIBCOG_01117	1.85e-89	-	-	-	S	-	-	-	Putative ABC-transporter type IV
CMMIBCOG_01118	4.08e-123	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CMMIBCOG_01119	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
CMMIBCOG_01120	4.33e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
CMMIBCOG_01121	5.46e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CMMIBCOG_01122	5.7e-236	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CMMIBCOG_01123	1.66e-306	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
CMMIBCOG_01124	5.02e-228	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
CMMIBCOG_01125	1.33e-273	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CMMIBCOG_01126	4.71e-263	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CMMIBCOG_01127	7.69e-148	-	-	-	-	-	-	-	-
CMMIBCOG_01128	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
CMMIBCOG_01129	9.1e-261	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMMIBCOG_01130	7.78e-202	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMMIBCOG_01131	6.62e-128	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
CMMIBCOG_01132	2.06e-25	-	-	-	-	-	-	-	-
CMMIBCOG_01134	2.76e-15	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
CMMIBCOG_01135	2.27e-146	-	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
CMMIBCOG_01137	7.24e-08	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
CMMIBCOG_01138	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CMMIBCOG_01139	5.03e-183	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
CMMIBCOG_01140	7.43e-314	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CMMIBCOG_01141	1.66e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
CMMIBCOG_01142	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
CMMIBCOG_01143	1.27e-186	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CMMIBCOG_01144	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_01145	9.26e-110	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CMMIBCOG_01146	8.24e-261	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CMMIBCOG_01147	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMMIBCOG_01148	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
CMMIBCOG_01149	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CMMIBCOG_01150	0.0	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
CMMIBCOG_01151	6.33e-186	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_01152	8.28e-281	-	-	-	E	-	-	-	Aminotransferase class I and II
CMMIBCOG_01153	3.28e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CMMIBCOG_01154	9.03e-258	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
CMMIBCOG_01155	5.48e-189	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CMMIBCOG_01156	3.73e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
CMMIBCOG_01157	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMMIBCOG_01158	3.38e-140	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMMIBCOG_01159	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01160	6.53e-53	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	homocysteine catabolic process
CMMIBCOG_01161	7.93e-141	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
CMMIBCOG_01162	6.42e-237	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
CMMIBCOG_01163	3.14e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMMIBCOG_01164	6.51e-162	-	-	-	S	-	-	-	alpha beta
CMMIBCOG_01165	3.25e-40	-	-	-	-	-	-	-	-
CMMIBCOG_01166	2.41e-259	-	-	-	L	-	-	-	Transposase
CMMIBCOG_01167	4.57e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CMMIBCOG_01168	3.69e-283	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
CMMIBCOG_01169	1.51e-234	-	-	-	-	-	-	-	-
CMMIBCOG_01170	8.63e-166	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CMMIBCOG_01171	6.74e-213	-	-	-	L	ko:K09384	-	ko00000	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CMMIBCOG_01172	3.05e-73	-	-	-	S	-	-	-	MazG-like family
CMMIBCOG_01173	4.23e-58	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
CMMIBCOG_01174	9.16e-105	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
CMMIBCOG_01175	2.68e-32	-	-	-	-	-	-	-	-
CMMIBCOG_01176	1.31e-288	-	-	-	L	-	-	-	Phage integrase family
CMMIBCOG_01177	6.67e-43	-	-	-	L	-	-	-	Excisionase from transposon Tn916
CMMIBCOG_01178	4.28e-254	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01179	1.18e-149	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
CMMIBCOG_01180	1.6e-129	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01181	3.98e-153	-	-	-	-	-	-	-	-
CMMIBCOG_01182	2.54e-98	-	-	-	-	-	-	-	-
CMMIBCOG_01183	5.74e-59	-	-	-	-	-	-	-	-
CMMIBCOG_01184	8.04e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMMIBCOG_01185	1.66e-162	-	-	-	KLT	-	-	-	serine threonine protein kinase
CMMIBCOG_01186	7.72e-177	-	3.6.3.44	-	V	ko:K06147,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
CMMIBCOG_01187	1.23e-201	-	3.6.3.44	-	V	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
CMMIBCOG_01188	2.91e-202	-	-	-	O	-	-	-	Thioredoxin
CMMIBCOG_01189	4.13e-166	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01190	6.54e-169	-	-	-	S	-	-	-	DUF218 domain
CMMIBCOG_01191	2.43e-301	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMMIBCOG_01192	9.85e-299	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
CMMIBCOG_01193	5.46e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
CMMIBCOG_01194	4.15e-209	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMMIBCOG_01195	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
CMMIBCOG_01196	1.28e-41	-	-	-	-	-	-	-	-
CMMIBCOG_01197	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CMMIBCOG_01198	1.58e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
CMMIBCOG_01199	3.32e-200	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMMIBCOG_01200	3.14e-192	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
CMMIBCOG_01201	4.13e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMMIBCOG_01202	1.59e-144	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01203	1.52e-98	-	-	-	-	-	-	-	-
CMMIBCOG_01205	1e-161	-	-	-	V	-	-	-	Abi-like protein
CMMIBCOG_01206	4.25e-26	-	-	-	V	-	-	-	Abi-like protein
CMMIBCOG_01207	5.99e-168	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
CMMIBCOG_01208	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CMMIBCOG_01209	1.27e-174	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CMMIBCOG_01210	7.15e-94	-	-	-	L	-	-	-	Helix-turn-helix domain
CMMIBCOG_01212	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
CMMIBCOG_01213	9.33e-309	dinF	-	-	V	-	-	-	MatE
CMMIBCOG_01214	7.75e-130	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMMIBCOG_01215	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMMIBCOG_01216	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CMMIBCOG_01217	8.5e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
CMMIBCOG_01218	1.37e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
CMMIBCOG_01219	1.02e-299	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
CMMIBCOG_01220	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
CMMIBCOG_01221	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
CMMIBCOG_01222	2.53e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
CMMIBCOG_01223	2.63e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
CMMIBCOG_01224	5.19e-308	-	-	-	T	-	-	-	Domain of unknown function (DUF4173)
CMMIBCOG_01225	4.22e-287	-	-	-	G	-	-	-	Major Facilitator Superfamily
CMMIBCOG_01226	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
CMMIBCOG_01227	3.32e-226	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMMIBCOG_01228	2.58e-152	-	-	-	-	-	-	-	-
CMMIBCOG_01229	1.81e-251	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CMMIBCOG_01230	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
CMMIBCOG_01231	8.22e-154	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
CMMIBCOG_01232	9.61e-93	-	-	-	L	-	-	-	Helix-turn-helix domain
CMMIBCOG_01233	8.73e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
CMMIBCOG_01234	4.49e-129	-	-	-	-	-	-	-	-
CMMIBCOG_01235	3.23e-247	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CMMIBCOG_01236	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMMIBCOG_01237	5.45e-153	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMMIBCOG_01238	4.3e-158	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
CMMIBCOG_01239	4.97e-271	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMMIBCOG_01240	7.07e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
CMMIBCOG_01241	3.83e-104	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMMIBCOG_01242	1.17e-125	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
CMMIBCOG_01243	1.29e-159	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMMIBCOG_01244	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
CMMIBCOG_01245	1.6e-246	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMMIBCOG_01246	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CMMIBCOG_01247	5.72e-200	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
CMMIBCOG_01248	6.83e-228	-	-	-	EG	-	-	-	EamA-like transporter family
CMMIBCOG_01249	1.18e-169	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CMMIBCOG_01250	2.34e-132	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
CMMIBCOG_01251	3.12e-310	-	-	-	T	-	-	-	Histidine kinase
CMMIBCOG_01252	8.7e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CMMIBCOG_01253	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
CMMIBCOG_01254	3.27e-150	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CMMIBCOG_01255	2.58e-311	-	-	-	T	-	-	-	Histidine kinase
CMMIBCOG_01256	4.04e-241	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_01257	5.91e-280	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMMIBCOG_01258	1.01e-290	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMMIBCOG_01259	1.12e-230	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CMMIBCOG_01260	1.45e-150	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
CMMIBCOG_01261	9.06e-317	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
CMMIBCOG_01262	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CMMIBCOG_01263	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
CMMIBCOG_01264	2.14e-98	-	-	-	-	-	-	-	-
CMMIBCOG_01265	5.58e-309	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMMIBCOG_01266	1.09e-171	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
CMMIBCOG_01267	3.66e-194	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
CMMIBCOG_01268	1.67e-219	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
CMMIBCOG_01269	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
CMMIBCOG_01270	1.43e-224	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
CMMIBCOG_01271	5.9e-206	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01272	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CMMIBCOG_01273	3.23e-219	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
CMMIBCOG_01274	3e-46	-	-	-	-	-	-	-	-
CMMIBCOG_01275	3.22e-247	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
CMMIBCOG_01276	9.2e-244	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
CMMIBCOG_01277	9.58e-92	-	-	-	-	-	-	-	-
CMMIBCOG_01278	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
CMMIBCOG_01279	1.5e-295	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
CMMIBCOG_01280	1.83e-202	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
CMMIBCOG_01281	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
CMMIBCOG_01282	2.21e-313	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CMMIBCOG_01283	3.58e-197	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
CMMIBCOG_01284	3.42e-195	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
CMMIBCOG_01285	9.23e-219	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
CMMIBCOG_01286	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMMIBCOG_01287	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
CMMIBCOG_01288	1.14e-140	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMMIBCOG_01289	1.51e-184	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
CMMIBCOG_01290	7.14e-256	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMMIBCOG_01291	4.21e-116	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMMIBCOG_01292	8.38e-239	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CMMIBCOG_01293	5.29e-238	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CMMIBCOG_01294	1.51e-52	-	-	-	-	-	-	-	-
CMMIBCOG_01295	7.63e-124	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CMMIBCOG_01296	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMMIBCOG_01297	1.72e-242	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
CMMIBCOG_01298	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
CMMIBCOG_01299	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
CMMIBCOG_01300	2.24e-127	-	-	-	F	-	-	-	NUDIX domain
CMMIBCOG_01301	8.16e-102	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMMIBCOG_01302	5.7e-287	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CMMIBCOG_01303	9.28e-219	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
CMMIBCOG_01305	3.48e-315	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
CMMIBCOG_01306	5.61e-181	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
CMMIBCOG_01307	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CMMIBCOG_01308	1.05e-273	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMMIBCOG_01309	4.97e-259	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
CMMIBCOG_01310	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMMIBCOG_01311	1.38e-251	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMMIBCOG_01312	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMMIBCOG_01313	6.85e-197	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMMIBCOG_01314	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
CMMIBCOG_01315	2.83e-79	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CMMIBCOG_01316	3.32e-241	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMMIBCOG_01317	3.88e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CMMIBCOG_01318	0.0	-	-	-	L	-	-	-	DNA helicase
CMMIBCOG_01319	8.36e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
CMMIBCOG_01320	2.49e-110	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMMIBCOG_01321	8.85e-72	-	-	-	M	-	-	-	Lysin motif
CMMIBCOG_01322	6.88e-170	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMMIBCOG_01323	3.34e-192	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMMIBCOG_01324	3.25e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CMMIBCOG_01325	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMMIBCOG_01326	1.62e-145	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
CMMIBCOG_01327	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
CMMIBCOG_01328	1.65e-244	-	-	-	-	-	-	-	-
CMMIBCOG_01329	1.62e-234	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
CMMIBCOG_01330	7.96e-129	-	-	-	-	-	-	-	-
CMMIBCOG_01331	5.66e-72	-	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
CMMIBCOG_01333	1.24e-152	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_01334	6.36e-280	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
CMMIBCOG_01335	2.75e-184	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CMMIBCOG_01336	6.42e-309	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
CMMIBCOG_01337	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CMMIBCOG_01338	2.38e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
CMMIBCOG_01339	1.77e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CMMIBCOG_01340	1.15e-163	-	-	-	-	-	-	-	-
CMMIBCOG_01341	4.56e-142	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
CMMIBCOG_01342	1.36e-287	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMMIBCOG_01343	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CMMIBCOG_01344	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
CMMIBCOG_01345	2.04e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CMMIBCOG_01346	5.38e-119	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMMIBCOG_01347	6.05e-65	-	-	-	V	-	-	-	DivIVA protein
CMMIBCOG_01348	9.14e-55	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
CMMIBCOG_01349	5.84e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CMMIBCOG_01350	4.66e-279	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMMIBCOG_01351	3.09e-309	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMMIBCOG_01352	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
CMMIBCOG_01353	3.3e-137	-	-	-	S	ko:K02664	-	ko00000,ko02035,ko02044	Pilus assembly protein, PilO
CMMIBCOG_01354	6.91e-212	-	-	-	NU	-	-	-	PFAM Fimbrial assembly family protein
CMMIBCOG_01355	6.5e-246	pilM	-	-	NU	ko:K02662	-	ko00000,ko02035,ko02044	Type IV pilus assembly protein PilM;
CMMIBCOG_01356	1.33e-195	pppA	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Bacterial Peptidase A24 N-terminal domain
CMMIBCOG_01357	7.95e-93	-	-	-	-	-	-	-	-
CMMIBCOG_01358	0.0	-	-	-	-	-	-	-	-
CMMIBCOG_01359	1.23e-293	tapC	-	-	U	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
CMMIBCOG_01360	9.26e-93	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	Prokaryotic N-terminal methylation motif
CMMIBCOG_01361	1.55e-135	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
CMMIBCOG_01362	3.4e-175	-	-	-	NU	ko:K02671	-	ko00000,ko02035,ko02044	Prokaryotic N-terminal methylation motif
CMMIBCOG_01363	0.0	pilB	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
CMMIBCOG_01364	0.0	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
CMMIBCOG_01365	0.0	-	-	-	-	-	-	-	-
CMMIBCOG_01366	4.66e-198	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CMMIBCOG_01367	6.69e-172	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CMMIBCOG_01368	1.75e-193	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CMMIBCOG_01369	3.37e-79	-	-	-	S	-	-	-	Thiamine-binding protein
CMMIBCOG_01370	1.78e-244	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CMMIBCOG_01371	1.8e-306	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
CMMIBCOG_01372	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
CMMIBCOG_01373	1.43e-189	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01374	1.43e-261	-	-	-	P	-	-	-	NMT1/THI5 like
CMMIBCOG_01375	6.32e-292	-	-	-	F	-	-	-	nucleoside hydrolase
CMMIBCOG_01376	8.46e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMMIBCOG_01377	4.14e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CMMIBCOG_01378	0.0	-	-	-	I	-	-	-	acetylesterase activity
CMMIBCOG_01379	1.93e-286	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CMMIBCOG_01380	1.19e-277	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CMMIBCOG_01381	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
CMMIBCOG_01383	3.68e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
CMMIBCOG_01384	2.86e-196	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CMMIBCOG_01385	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
CMMIBCOG_01386	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CMMIBCOG_01387	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
CMMIBCOG_01388	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
CMMIBCOG_01389	1.67e-221	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
CMMIBCOG_01390	6.1e-151	-	-	-	S	-	-	-	Vitamin K epoxide reductase
CMMIBCOG_01391	3.63e-216	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
CMMIBCOG_01392	1.07e-186	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CMMIBCOG_01393	1.5e-29	-	-	-	S	ko:K07001	-	ko00000	lipid catabolic process
CMMIBCOG_01394	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CMMIBCOG_01395	1.95e-226	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
CMMIBCOG_01396	2.29e-204	-	-	-	S	-	-	-	Patatin-like phospholipase
CMMIBCOG_01397	4.36e-239	-	-	-	K	-	-	-	LysR substrate binding domain protein
CMMIBCOG_01398	1.35e-306	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
CMMIBCOG_01399	7.31e-154	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
CMMIBCOG_01400	2.78e-46	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIBCOG_01401	3.25e-193	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIBCOG_01402	2.57e-123	cas4	3.1.12.1	-	L	ko:K07464,ko:K15342	-	ko00000,ko01000,ko02048,ko03400	Domain of unknown function DUF83
CMMIBCOG_01403	6.73e-183	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
CMMIBCOG_01404	5.96e-270	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csd1)
CMMIBCOG_01405	5.26e-130	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
CMMIBCOG_01406	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
CMMIBCOG_01407	3.29e-160	-	-	-	S	-	-	-	Fic/DOC family
CMMIBCOG_01408	2.08e-23	-	-	-	S	-	-	-	Fic/DOC family
CMMIBCOG_01409	1.48e-111	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
CMMIBCOG_01411	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMMIBCOG_01412	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
CMMIBCOG_01413	8.41e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
CMMIBCOG_01414	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
CMMIBCOG_01415	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CMMIBCOG_01416	2.85e-135	-	-	-	K	-	-	-	MarR family
CMMIBCOG_01417	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
CMMIBCOG_01418	1.12e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_01419	2.53e-254	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CMMIBCOG_01420	1.21e-231	-	-	-	G	-	-	-	Transporter major facilitator family protein
CMMIBCOG_01421	0.0	-	3.2.1.40	-	E	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
CMMIBCOG_01422	4.89e-273	-	-	-	U	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
CMMIBCOG_01423	4.38e-147	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
CMMIBCOG_01424	7e-18	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMMIBCOG_01425	5.7e-279	-	-	-	U	ko:K08168,ko:K18926	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
CMMIBCOG_01426	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
CMMIBCOG_01427	3.56e-280	-	-	-	P	-	-	-	Major Facilitator Superfamily
CMMIBCOG_01428	1.53e-286	-	-	-	M	-	-	-	Belongs to the D-alanine--D-alanine ligase family
CMMIBCOG_01429	4.03e-73	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_01430	9.19e-42	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_01431	1.42e-306	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CMMIBCOG_01432	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 43
CMMIBCOG_01433	0.0	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CMMIBCOG_01435	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
CMMIBCOG_01436	4.32e-284	-	-	-	G	-	-	-	MFS/sugar transport protein
CMMIBCOG_01437	1.9e-174	-	-	-	K	-	-	-	transcriptional regulator
CMMIBCOG_01438	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
CMMIBCOG_01439	6.02e-305	-	-	-	G	-	-	-	Transporter major facilitator family protein
CMMIBCOG_01440	1.99e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_01441	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
CMMIBCOG_01442	3.74e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMMIBCOG_01443	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
CMMIBCOG_01444	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
CMMIBCOG_01445	5.91e-199	-	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
CMMIBCOG_01446	7.49e-178	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMMIBCOG_01447	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
CMMIBCOG_01448	1.05e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMMIBCOG_01449	8.4e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMMIBCOG_01451	2.41e-259	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
CMMIBCOG_01452	4.43e-163	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
CMMIBCOG_01453	6.35e-229	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
CMMIBCOG_01454	3.15e-298	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
CMMIBCOG_01455	3.68e-96	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
CMMIBCOG_01456	4.24e-246	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
CMMIBCOG_01457	0.0	-	3.6.4.12	-	L	ko:K03658	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01458	1.05e-30	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
CMMIBCOG_01459	1.63e-283	-	-	-	L	ko:K07496	-	ko00000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01460	2.03e-92	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CMMIBCOG_01461	4.72e-134	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
CMMIBCOG_01462	0.0	-	-	-	V	-	-	-	Domain of unknown function (DUF3427)
CMMIBCOG_01463	2.94e-99	-	-	-	-	-	-	-	-
CMMIBCOG_01464	1.05e-97	-	-	-	S	-	-	-	Bacterial PH domain
CMMIBCOG_01465	7.08e-315	-	-	-	S	-	-	-	zinc finger
CMMIBCOG_01467	5.31e-17	-	-	-	-	-	-	-	-
CMMIBCOG_01468	2.44e-05	-	-	-	-	-	-	-	-
CMMIBCOG_01469	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CMMIBCOG_01470	3.3e-158	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMMIBCOG_01471	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMMIBCOG_01472	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
CMMIBCOG_01473	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMMIBCOG_01474	6.79e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMMIBCOG_01475	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
CMMIBCOG_01476	6.79e-52	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
CMMIBCOG_01477	4.54e-171	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CMMIBCOG_01478	4.01e-314	-	-	-	G	-	-	-	Major Facilitator Superfamily
CMMIBCOG_01479	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
CMMIBCOG_01480	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
CMMIBCOG_01481	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
CMMIBCOG_01482	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
CMMIBCOG_01483	1.1e-301	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
CMMIBCOG_01484	2.31e-282	-	-	-	S	-	-	-	Protein of unknown function DUF58
CMMIBCOG_01485	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
CMMIBCOG_01486	7e-210	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
CMMIBCOG_01487	2.2e-148	-	-	-	B	-	-	-	Belongs to the OprB family
CMMIBCOG_01488	1.82e-129	-	-	-	T	-	-	-	Forkhead associated domain
CMMIBCOG_01489	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMMIBCOG_01490	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMMIBCOG_01491	5.8e-137	-	-	-	-	-	-	-	-
CMMIBCOG_01492	5.19e-232	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
CMMIBCOG_01493	2.24e-162	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMMIBCOG_01494	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
CMMIBCOG_01495	1.32e-57	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
CMMIBCOG_01496	5.53e-30	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Drug resistance MFS transporter, drug H antiporter-2 family
CMMIBCOG_01497	1.45e-297	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
CMMIBCOG_01498	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
CMMIBCOG_01499	1.13e-181	-	-	-	K	-	-	-	DeoR C terminal sensor domain
CMMIBCOG_01500	1.41e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
CMMIBCOG_01501	4.15e-280	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
CMMIBCOG_01502	0.0	pon1	-	-	M	-	-	-	Transglycosylase
CMMIBCOG_01503	3.02e-170	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
CMMIBCOG_01504	2.12e-274	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
CMMIBCOG_01505	7.25e-133	-	-	-	J	-	-	-	TM2 domain
CMMIBCOG_01506	9.62e-247	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CMMIBCOG_01507	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
CMMIBCOG_01508	4.34e-301	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
CMMIBCOG_01509	1.66e-92	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
CMMIBCOG_01510	1.26e-266	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
CMMIBCOG_01511	2.6e-196	-	-	-	I	-	-	-	Alpha/beta hydrolase family
CMMIBCOG_01512	2.77e-147	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
CMMIBCOG_01513	3.24e-77	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
CMMIBCOG_01514	1.07e-220	-	-	-	S	ko:K21688	-	ko00000	G5
CMMIBCOG_01515	4.23e-115	-	-	-	-	-	-	-	-
CMMIBCOG_01516	2.32e-94	-	-	-	-	-	-	-	-
CMMIBCOG_01517	4.77e-38	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
CMMIBCOG_01518	4.61e-95	-	-	-	-	-	-	-	-
CMMIBCOG_01519	1.06e-123	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
CMMIBCOG_01520	0.0	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
CMMIBCOG_01521	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
CMMIBCOG_01522	5.43e-189	-	-	-	P	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01523	2.74e-209	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01524	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_01525	8.42e-237	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CMMIBCOG_01526	2.41e-259	-	-	-	L	-	-	-	Transposase
CMMIBCOG_01527	4.57e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CMMIBCOG_01528	3.69e-283	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
CMMIBCOG_01529	1.51e-234	-	-	-	-	-	-	-	-
CMMIBCOG_01530	1.63e-235	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMMIBCOG_01531	5.46e-86	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_01532	1.04e-175	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_01533	4.31e-207	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
CMMIBCOG_01534	1.49e-185	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01535	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
CMMIBCOG_01536	1.66e-72	yccF	-	-	S	-	-	-	Inner membrane component domain
CMMIBCOG_01537	4.85e-190	-	-	-	V	-	-	-	Abi-like protein
CMMIBCOG_01539	9.4e-107	-	-	-	K	-	-	-	SIR2-like domain
CMMIBCOG_01540	6.91e-99	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
CMMIBCOG_01541	2.39e-97	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
CMMIBCOG_01542	7.34e-80	-	-	-	K	-	-	-	Helix-turn-helix domain protein
CMMIBCOG_01545	5.55e-26	-	-	-	L	-	-	-	Helix-turn-helix domain
CMMIBCOG_01546	8.31e-63	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CMMIBCOG_01547	1.62e-51	-	-	-	L	-	-	-	PFAM Integrase catalytic
CMMIBCOG_01548	1.56e-226	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
CMMIBCOG_01549	6.64e-177	-	-	-	L	-	-	-	PFAM Integrase catalytic
CMMIBCOG_01550	1.99e-56	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CMMIBCOG_01551	5.48e-162	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
CMMIBCOG_01552	4.11e-112	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
CMMIBCOG_01553	6.53e-159	-	-	-	-	-	-	-	-
CMMIBCOG_01554	9.03e-106	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CMMIBCOG_01555	1.06e-119	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CMMIBCOG_01556	3.61e-113	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
CMMIBCOG_01557	4.57e-27	-	-	-	M	-	-	-	PFAM Glycosyl transferase, group 1
CMMIBCOG_01558	7.97e-271	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
CMMIBCOG_01559	2.47e-272	-	-	-	M	-	-	-	Domain of unknown function (DUF1972)
CMMIBCOG_01560	1.61e-258	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01561	1.11e-304	-	-	-	M	ko:K00713	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferases group 1
CMMIBCOG_01562	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
CMMIBCOG_01563	3.16e-252	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
CMMIBCOG_01564	1.37e-141	-	-	-	H	-	-	-	Hexapeptide repeat of succinyl-transferase
CMMIBCOG_01565	1.66e-269	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
CMMIBCOG_01566	8.25e-249	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01568	4.04e-226	-	-	-	S	-	-	-	EpsG family
CMMIBCOG_01570	9.52e-86	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
CMMIBCOG_01571	4.8e-66	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
CMMIBCOG_01573	3.71e-182	-	-	-	V	-	-	-	Abi-like protein
CMMIBCOG_01574	1.22e-258	-	-	-	-	-	-	-	-
CMMIBCOG_01575	2.41e-259	-	-	-	L	-	-	-	Transposase
CMMIBCOG_01576	4.57e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CMMIBCOG_01577	3.69e-283	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
CMMIBCOG_01578	1.51e-234	-	-	-	-	-	-	-	-
CMMIBCOG_01579	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
CMMIBCOG_01580	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
CMMIBCOG_01581	1.93e-242	staP	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
CMMIBCOG_01582	2.52e-63	-	-	-	-	-	-	-	-
CMMIBCOG_01583	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
CMMIBCOG_01584	4.1e-310	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
CMMIBCOG_01585	3.49e-155	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
CMMIBCOG_01586	2.98e-212	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
CMMIBCOG_01587	8.95e-308	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CMMIBCOG_01588	6.55e-251	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMMIBCOG_01589	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01590	7.16e-233	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
CMMIBCOG_01591	2.5e-206	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01592	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_01593	3.48e-163	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CMMIBCOG_01594	6.62e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CMMIBCOG_01595	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
CMMIBCOG_01596	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
CMMIBCOG_01597	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
CMMIBCOG_01598	5.01e-164	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
CMMIBCOG_01599	0.0	araB	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
CMMIBCOG_01600	6.03e-270	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMMIBCOG_01601	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
CMMIBCOG_01602	6.71e-241	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMMIBCOG_01603	6.85e-307	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
CMMIBCOG_01604	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMMIBCOG_01605	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
CMMIBCOG_01606	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
CMMIBCOG_01607	9.75e-85	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
CMMIBCOG_01609	1.16e-155	-	-	-	S	-	-	-	CYTH
CMMIBCOG_01610	9.17e-217	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
CMMIBCOG_01611	1.19e-233	-	-	-	-	-	-	-	-
CMMIBCOG_01612	2.72e-266	-	-	-	-	-	-	-	-
CMMIBCOG_01613	2.27e-192	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
CMMIBCOG_01614	1.32e-156	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CMMIBCOG_01615	2.85e-60	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CMMIBCOG_01616	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMMIBCOG_01617	5.5e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMMIBCOG_01618	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMMIBCOG_01619	3.82e-190	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMMIBCOG_01620	6.4e-93	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMMIBCOG_01621	9.64e-42	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMMIBCOG_01622	6.89e-190	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CMMIBCOG_01623	1.2e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CMMIBCOG_01625	1.21e-13	-	-	-	K	-	-	-	BetR domain
CMMIBCOG_01630	1.12e-35	-	-	-	-	-	-	-	-
CMMIBCOG_01631	1.62e-20	-	-	-	-	-	-	-	-
CMMIBCOG_01634	1.85e-125	-	-	-	L	-	-	-	HNH endonuclease
CMMIBCOG_01635	1.53e-53	-	-	-	-	-	-	-	-
CMMIBCOG_01636	5.59e-298	-	-	-	S	-	-	-	Terminase
CMMIBCOG_01637	5.22e-203	-	-	-	S	-	-	-	Phage portal protein
CMMIBCOG_01638	2.65e-269	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
CMMIBCOG_01639	2.21e-56	-	-	-	-	-	-	-	-
CMMIBCOG_01640	1.13e-47	-	-	-	-	-	-	-	-
CMMIBCOG_01641	4.48e-78	-	-	-	-	-	-	-	-
CMMIBCOG_01642	7.05e-72	-	-	-	-	-	-	-	-
CMMIBCOG_01643	6.57e-49	-	-	-	-	-	-	-	-
CMMIBCOG_01644	1.65e-259	-	-	-	NT	-	-	-	phage tail tape measure protein
CMMIBCOG_01647	3.85e-24	-	-	-	-	-	-	-	-
CMMIBCOG_01648	1.6e-94	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
CMMIBCOG_01649	1.5e-13	xhlB	-	-	S	-	-	-	SPP1 phage holin
CMMIBCOG_01650	2.15e-113	-	-	-	L	-	-	-	Phage integrase family
CMMIBCOG_01651	0.0	frc	2.8.3.15, 2.8.3.16	-	C	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CMMIBCOG_01652	8.22e-248	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CMMIBCOG_01653	0.0	oxc	4.1.1.8	-	EH	ko:K01577	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
CMMIBCOG_01654	3.8e-224	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CMMIBCOG_01655	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
CMMIBCOG_01656	2.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CMMIBCOG_01657	8.22e-154	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
CMMIBCOG_01658	9.61e-93	-	-	-	L	-	-	-	Helix-turn-helix domain
CMMIBCOG_01659	8.64e-120	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
CMMIBCOG_01660	1.09e-173	-	-	-	-	-	-	-	-
CMMIBCOG_01661	1.1e-172	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
CMMIBCOG_01662	9.55e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMMIBCOG_01663	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CMMIBCOG_01664	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMMIBCOG_01665	0.0	-	-	-	S	-	-	-	domain protein
CMMIBCOG_01666	1.99e-90	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
CMMIBCOG_01667	1.09e-104	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
CMMIBCOG_01668	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CMMIBCOG_01669	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
CMMIBCOG_01670	1.43e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
CMMIBCOG_01671	1.4e-261	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CMMIBCOG_01672	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMMIBCOG_01673	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMMIBCOG_01674	1.58e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMMIBCOG_01675	1.46e-167	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CMMIBCOG_01676	2.55e-168	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
CMMIBCOG_01677	1.21e-134	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMMIBCOG_01678	9.8e-262	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
CMMIBCOG_01679	1.84e-186	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Heavy metal translocating P-type atpase
CMMIBCOG_01680	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMMIBCOG_01681	1.66e-210	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
CMMIBCOG_01682	2.91e-189	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CMMIBCOG_01683	2.82e-105	-	-	-	-	-	-	-	-
CMMIBCOG_01684	1.05e-265	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CMMIBCOG_01685	4.7e-68	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
CMMIBCOG_01687	1.1e-177	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMMIBCOG_01689	1.16e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CMMIBCOG_01690	3.05e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMMIBCOG_01691	3.97e-107	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
CMMIBCOG_01692	7.12e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CMMIBCOG_01693	3.76e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMMIBCOG_01694	3.94e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMMIBCOG_01695	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
CMMIBCOG_01696	4.54e-215	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
CMMIBCOG_01697	3.02e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CMMIBCOG_01698	6.68e-85	-	-	-	-	-	-	-	-
CMMIBCOG_01699	1.76e-258	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CMMIBCOG_01700	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
CMMIBCOG_01701	3.77e-249	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CMMIBCOG_01702	1.89e-190	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
CMMIBCOG_01703	1.05e-310	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMMIBCOG_01704	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
CMMIBCOG_01705	2.31e-210	-	-	-	I	-	-	-	Acyltransferase family
CMMIBCOG_01706	8.88e-193	-	-	GT2	M	ko:K13670	-	ko00000,ko01000	Glycosyltransferase like family 2
CMMIBCOG_01707	2.46e-236	-	-	-	S	-	-	-	Glucosyl transferase GtrII
CMMIBCOG_01708	3.52e-142	-	1.1.1.339	-	GM	ko:K19180	ko00523,ko01130,map00523,map01130	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
CMMIBCOG_01709	6.26e-254	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CMMIBCOG_01710	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CMMIBCOG_01711	3e-221	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CMMIBCOG_01712	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CMMIBCOG_01713	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
CMMIBCOG_01714	4.28e-125	-	-	-	-	-	-	-	-
CMMIBCOG_01715	1.61e-16	-	-	-	-	-	-	-	-
CMMIBCOG_01716	1.49e-133	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
CMMIBCOG_01717	3.13e-242	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
CMMIBCOG_01718	2.18e-76	-	-	-	-	-	-	-	-
CMMIBCOG_01720	2.95e-117	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMMIBCOG_01721	5.97e-62	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMMIBCOG_01722	2.08e-42	yuxJ	-	-	EGP	-	-	-	Major facilitator Superfamily
CMMIBCOG_01724	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
CMMIBCOG_01725	5.52e-301	-	-	-	V	-	-	-	ABC transporter permease
CMMIBCOG_01726	4.32e-209	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CMMIBCOG_01727	7.48e-191	-	-	-	T	ko:K06950	-	ko00000	HD domain
CMMIBCOG_01728	1.17e-214	-	-	-	S	-	-	-	Glutamine amidotransferase domain
CMMIBCOG_01729	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CMMIBCOG_01730	8.42e-236	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
CMMIBCOG_01731	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminus
CMMIBCOG_01732	1.77e-27	-	-	-	G	-	-	-	Alpha galactosidase A
CMMIBCOG_01733	2.55e-288	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMMIBCOG_01734	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01735	6.8e-162	-	-	-	-	-	-	-	-
CMMIBCOG_01736	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMMIBCOG_01737	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMMIBCOG_01738	7.33e-272	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
CMMIBCOG_01740	3.18e-197	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMMIBCOG_01741	1.2e-293	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
CMMIBCOG_01742	7.99e-196	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01743	4.05e-215	-	-	-	G	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01744	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_01745	6.84e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMMIBCOG_01746	2.23e-266	-	-	-	M	-	-	-	probably involved in cell wall
CMMIBCOG_01747	6.66e-268	-	-	-	M	-	-	-	probably involved in cell wall
CMMIBCOG_01748	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
CMMIBCOG_01749	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
CMMIBCOG_01750	2.4e-240	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
CMMIBCOG_01751	5.62e-297	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
CMMIBCOG_01752	5.46e-192	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMMIBCOG_01753	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
CMMIBCOG_01754	1.6e-220	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CMMIBCOG_01755	1.13e-220	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
CMMIBCOG_01756	7.7e-196	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01757	3.86e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_01758	8.58e-271	-	-	-	GK	-	-	-	ROK family
CMMIBCOG_01759	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
CMMIBCOG_01760	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01761	8.11e-175	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
CMMIBCOG_01763	0.0	lacZ3	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
CMMIBCOG_01764	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMMIBCOG_01765	2.28e-138	-	-	-	-	-	-	-	-
CMMIBCOG_01766	1.04e-245	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMMIBCOG_01767	1.84e-21	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Glycosyl hydrolase family 26
CMMIBCOG_01768	1.1e-161	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
CMMIBCOG_01770	5.91e-167	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
CMMIBCOG_01771	6.08e-63	-	-	-	-	-	-	-	-
CMMIBCOG_01772	1.61e-146	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
CMMIBCOG_01773	1.17e-227	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
CMMIBCOG_01774	7.78e-89	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMMIBCOG_01775	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CMMIBCOG_01776	1.08e-157	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CMMIBCOG_01777	1.74e-197	-	-	-	S	ko:K07133	-	ko00000	AAA domain
CMMIBCOG_01778	1.73e-176	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
CMMIBCOG_01779	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
CMMIBCOG_01780	5.73e-136	-	-	-	S	-	-	-	Protein of unknown function, DUF624
CMMIBCOG_01781	5.87e-192	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMMIBCOG_01782	7.45e-197	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01783	1.03e-220	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CMMIBCOG_01784	9.58e-227	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
CMMIBCOG_01785	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
CMMIBCOG_01786	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_01787	4.5e-173	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
CMMIBCOG_01788	3.85e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
CMMIBCOG_01789	1.02e-66	nfrA	-	-	C	-	-	-	Nitroreductase family
CMMIBCOG_01790	6.3e-88	nfrA	-	-	C	-	-	-	Nitroreductase family
CMMIBCOG_01792	5.31e-17	-	-	-	-	-	-	-	-
CMMIBCOG_01793	5.27e-186	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
CMMIBCOG_01794	3.8e-291	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
CMMIBCOG_01795	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMMIBCOG_01796	1.19e-33	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
CMMIBCOG_01798	7.79e-205	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01799	5.46e-203	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01800	2.78e-309	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMMIBCOG_01801	3.13e-296	-	-	-	GK	-	-	-	ROK family
CMMIBCOG_01802	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
CMMIBCOG_01803	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
CMMIBCOG_01804	7.48e-193	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
CMMIBCOG_01805	8.25e-142	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
CMMIBCOG_01806	1.58e-06	-	-	-	L	-	-	-	Transposase, Mutator family
CMMIBCOG_01807	3.59e-115	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
CMMIBCOG_01808	1.37e-107	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
CMMIBCOG_01809	1.19e-158	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMMIBCOG_01810	1.37e-115	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
CMMIBCOG_01811	7.82e-150	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01812	1.13e-150	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMMIBCOG_01813	2.76e-186	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
CMMIBCOG_01814	1.85e-117	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CMMIBCOG_01815	2.1e-142	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CMMIBCOG_01817	5.31e-17	-	-	-	-	-	-	-	-
CMMIBCOG_01818	1.65e-109	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
CMMIBCOG_01819	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
CMMIBCOG_01820	3.31e-174	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CMMIBCOG_01821	2.08e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
CMMIBCOG_01822	2.37e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
CMMIBCOG_01823	9.19e-222	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMMIBCOG_01824	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
CMMIBCOG_01825	1.26e-268	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMMIBCOG_01826	8.76e-169	-	-	-	K	-	-	-	LytTr DNA-binding domain
CMMIBCOG_01827	1.24e-174	-	-	-	T	-	-	-	GHKL domain
CMMIBCOG_01828	2.62e-272	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
CMMIBCOG_01829	3.18e-62	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
CMMIBCOG_01830	2e-79	-	-	-	-	-	-	-	-
CMMIBCOG_01831	2.2e-178	-	-	-	-	-	-	-	-
CMMIBCOG_01832	9.28e-224	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CMMIBCOG_01833	6.66e-306	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CMMIBCOG_01834	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
CMMIBCOG_01835	8.22e-154	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
CMMIBCOG_01836	9.61e-93	-	-	-	L	-	-	-	Helix-turn-helix domain
CMMIBCOG_01837	5.41e-127	-	-	-	S	-	-	-	GtrA-like protein
CMMIBCOG_01838	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
CMMIBCOG_01839	6.77e-154	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score
CMMIBCOG_01840	1e-103	ypeA	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01841	1.76e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMMIBCOG_01842	1.31e-268	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
CMMIBCOG_01843	1.48e-302	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CMMIBCOG_01844	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
CMMIBCOG_01845	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CMMIBCOG_01846	2.24e-06	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
CMMIBCOG_01847	1.08e-17	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
CMMIBCOG_01848	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
CMMIBCOG_01849	2.89e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
CMMIBCOG_01851	5.31e-17	-	-	-	-	-	-	-	-
CMMIBCOG_01852	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
CMMIBCOG_01853	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
CMMIBCOG_01854	3.13e-211	-	-	-	O	-	-	-	Thioredoxin
CMMIBCOG_01856	8.59e-254	rpfB	-	-	S	ko:K21688	-	ko00000	G5
CMMIBCOG_01857	7.35e-221	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMMIBCOG_01858	7.59e-215	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CMMIBCOG_01859	8.42e-142	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
CMMIBCOG_01860	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
CMMIBCOG_01861	2.21e-156	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
CMMIBCOG_01862	0.0	-	-	-	M	-	-	-	Conserved repeat domain
CMMIBCOG_01863	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
CMMIBCOG_01864	0.0	-	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
CMMIBCOG_01865	6.29e-17	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CMMIBCOG_01866	1.85e-156	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CMMIBCOG_01868	5.61e-20	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
CMMIBCOG_01869	6.95e-231	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMMIBCOG_01870	1.49e-271	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CMMIBCOG_01871	3.04e-221	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
CMMIBCOG_01872	4.45e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
CMMIBCOG_01873	2.6e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
CMMIBCOG_01874	2.26e-244	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
CMMIBCOG_01875	1.39e-57	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMMIBCOG_01876	2.68e-19	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family