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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KHOLMADN_00001	2.62e-08	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
KHOLMADN_00002	1.49e-48	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
KHOLMADN_00003	5.79e-167	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KHOLMADN_00004	3.07e-54	-	-	-	I	-	-	-	Alpha/beta hydrolase family
KHOLMADN_00005	1.54e-138	-	-	-	L	-	-	-	Integrase
KHOLMADN_00006	2.63e-58	-	-	-	K	-	-	-	transcriptional regulator
KHOLMADN_00007	2.82e-08	-	-	-	GM	-	-	-	NmrA-like family
KHOLMADN_00008	3.85e-30	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
KHOLMADN_00009	2.36e-98	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KHOLMADN_00010	6.11e-96	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
KHOLMADN_00011	7.28e-101	ywnA	-	-	K	-	-	-	Transcriptional regulator
KHOLMADN_00012	4.71e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
KHOLMADN_00013	6.29e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KHOLMADN_00014	6.34e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00015	3.1e-129	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
KHOLMADN_00016	1.45e-157	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
KHOLMADN_00017	3.93e-248	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
KHOLMADN_00018	1.76e-279	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
KHOLMADN_00019	3.27e-228	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHOLMADN_00020	2.93e-259	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
KHOLMADN_00021	5.86e-190	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
KHOLMADN_00022	4.36e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KHOLMADN_00023	7.7e-212	yvgN	-	-	C	-	-	-	Aldo keto reductase
KHOLMADN_00024	1.02e-206	-	-	-	S	-	-	-	DUF218 domain
KHOLMADN_00026	7.8e-124	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KHOLMADN_00027	1.49e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KHOLMADN_00028	1.24e-162	-	-	-	S	-	-	-	Phage minor capsid protein 2
KHOLMADN_00031	8.25e-271	-	-	-	E	-	-	-	Aminotransferase
KHOLMADN_00032	8.71e-139	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
KHOLMADN_00033	8.33e-311	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
KHOLMADN_00034	7.89e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
KHOLMADN_00035	1.98e-40	-	-	-	S	-	-	-	Fic/DOC family
KHOLMADN_00036	4.94e-76	-	-	-	S	-	-	-	Fic/DOC family
KHOLMADN_00037	2.02e-117	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KHOLMADN_00038	3.51e-137	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KHOLMADN_00039	5.43e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
KHOLMADN_00040	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
KHOLMADN_00041	2.91e-153	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
KHOLMADN_00042	2.34e-42	odh	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD NADP octopine nopaline dehydrogenase
KHOLMADN_00043	8.78e-69	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
KHOLMADN_00044	2.37e-15	odh	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD NADP octopine nopaline dehydrogenase
KHOLMADN_00045	2.34e-10	odh	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
KHOLMADN_00046	3.59e-11	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KHOLMADN_00047	3.57e-56	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KHOLMADN_00048	3.66e-43	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KHOLMADN_00050	4.11e-310	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
KHOLMADN_00051	4.66e-100	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KHOLMADN_00052	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
KHOLMADN_00054	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
KHOLMADN_00055	3.75e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
KHOLMADN_00056	6.88e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
KHOLMADN_00057	1.64e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
KHOLMADN_00058	3.75e-100	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
KHOLMADN_00059	8.29e-08	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
KHOLMADN_00060	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
KHOLMADN_00061	7.86e-92	-	-	-	S	-	-	-	Belongs to the HesB IscA family
KHOLMADN_00062	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
KHOLMADN_00063	2.53e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
KHOLMADN_00064	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHOLMADN_00065	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHOLMADN_00066	1.24e-132	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHOLMADN_00067	8.93e-218	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
KHOLMADN_00068	1.24e-195	-	-	-	D	-	-	-	DNA integration
KHOLMADN_00069	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHOLMADN_00070	8.52e-211	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
KHOLMADN_00071	5.87e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHOLMADN_00072	6.95e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHOLMADN_00073	4.96e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
KHOLMADN_00074	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
KHOLMADN_00075	1.17e-215	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
KHOLMADN_00076	5.71e-145	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
KHOLMADN_00077	1.69e-277	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
KHOLMADN_00078	2.71e-197	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
KHOLMADN_00079	1.34e-139	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
KHOLMADN_00080	9.19e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHOLMADN_00081	1.78e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHOLMADN_00082	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00083	8.09e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KHOLMADN_00084	1.49e-201	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
KHOLMADN_00085	5.68e-297	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
KHOLMADN_00086	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHOLMADN_00087	1.83e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KHOLMADN_00088	1.33e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
KHOLMADN_00089	3.8e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
KHOLMADN_00090	2.27e-67	-	-	-	M	-	-	-	Lysin motif
KHOLMADN_00091	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KHOLMADN_00092	1.56e-253	-	-	-	S	-	-	-	Helix-turn-helix domain
KHOLMADN_00094	2.89e-112	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHOLMADN_00095	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KHOLMADN_00096	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHOLMADN_00097	3.96e-181	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHOLMADN_00098	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHOLMADN_00099	4.04e-173	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
KHOLMADN_00100	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
KHOLMADN_00101	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
KHOLMADN_00102	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KHOLMADN_00104	1.15e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KHOLMADN_00105	1.16e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHOLMADN_00106	1.38e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KHOLMADN_00107	5.64e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
KHOLMADN_00108	3.38e-293	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
KHOLMADN_00109	3.01e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHOLMADN_00110	2.3e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KHOLMADN_00111	1.01e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KHOLMADN_00112	2.87e-219	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHOLMADN_00113	1.34e-279	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KHOLMADN_00114	7.42e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KHOLMADN_00115	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHOLMADN_00116	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KHOLMADN_00117	7.15e-232	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KHOLMADN_00118	7.03e-216	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHOLMADN_00119	2.75e-165	-	-	-	EGP	-	-	-	Major Facilitator
KHOLMADN_00120	2.54e-120	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
KHOLMADN_00121	2.72e-261	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHOLMADN_00122	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHOLMADN_00123	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KHOLMADN_00124	3.59e-240	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
KHOLMADN_00125	1.25e-198	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KHOLMADN_00126	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHOLMADN_00127	5.17e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
KHOLMADN_00128	9.35e-101	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHOLMADN_00129	3.53e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
KHOLMADN_00130	1.44e-82	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
KHOLMADN_00131	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
KHOLMADN_00132	1.02e-161	-	-	-	F	-	-	-	glutamine amidotransferase
KHOLMADN_00133	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KHOLMADN_00134	1.89e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KHOLMADN_00135	3.91e-244	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
KHOLMADN_00136	5.07e-189	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
KHOLMADN_00137	3.47e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
KHOLMADN_00138	6.46e-215	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
KHOLMADN_00139	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
KHOLMADN_00141	6.45e-202	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
KHOLMADN_00142	1.37e-35	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
KHOLMADN_00143	9.55e-222	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
KHOLMADN_00145	2.14e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KHOLMADN_00146	1.19e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00147	1.32e-146	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLMADN_00148	5.39e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
KHOLMADN_00150	1.58e-102	-	-	-	S	-	-	-	MmgE/PrpD family
KHOLMADN_00151	3.62e-215	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
KHOLMADN_00152	1.71e-184	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
KHOLMADN_00153	2.15e-100	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
KHOLMADN_00154	6.91e-98	yxeN	-	-	U	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
KHOLMADN_00155	1.03e-59	yxeL	-	-	K	-	-	-	acetyltransferase
KHOLMADN_00156	2.22e-78	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
KHOLMADN_00157	6.85e-258	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
KHOLMADN_00158	1.28e-275	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KHOLMADN_00159	1.14e-105	-	-	-	K	-	-	-	Transcriptional regulator
KHOLMADN_00160	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHOLMADN_00161	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHOLMADN_00162	4.23e-76	-	-	-	-	-	-	-	-
KHOLMADN_00163	4.11e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KHOLMADN_00164	5.15e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
KHOLMADN_00165	1.62e-70	-	-	-	-	-	-	-	-
KHOLMADN_00167	1.37e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KHOLMADN_00168	4.88e-282	-	-	-	P	-	-	-	Chloride transporter, ClC family
KHOLMADN_00169	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KHOLMADN_00170	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHOLMADN_00171	9.07e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
KHOLMADN_00172	2.63e-210	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHOLMADN_00173	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
KHOLMADN_00174	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHOLMADN_00175	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
KHOLMADN_00176	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHOLMADN_00177	9.41e-298	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KHOLMADN_00178	2.68e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
KHOLMADN_00179	6.4e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KHOLMADN_00180	1.93e-220	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
KHOLMADN_00181	2.09e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHOLMADN_00182	8.79e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHOLMADN_00183	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHOLMADN_00184	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHOLMADN_00185	7.99e-299	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
KHOLMADN_00186	9.19e-244	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHOLMADN_00187	1.04e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
KHOLMADN_00188	7.28e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHOLMADN_00189	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
KHOLMADN_00190	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
KHOLMADN_00191	4.68e-298	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
KHOLMADN_00192	3.88e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KHOLMADN_00193	2.81e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00194	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLMADN_00195	9.04e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
KHOLMADN_00196	1.37e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
KHOLMADN_00197	1.56e-231	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
KHOLMADN_00198	4.18e-147	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
KHOLMADN_00199	4.66e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KHOLMADN_00200	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHOLMADN_00201	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KHOLMADN_00203	4.68e-27	-	-	-	S	-	-	-	zinc-ribbon domain
KHOLMADN_00204	1.13e-52	-	-	-	-	-	-	-	-
KHOLMADN_00205	2.39e-12	-	-	-	M	-	-	-	LysM domain
KHOLMADN_00206	1.11e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KHOLMADN_00207	1.87e-276	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
KHOLMADN_00208	1.67e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHOLMADN_00209	6.81e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KHOLMADN_00210	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KHOLMADN_00211	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHOLMADN_00213	8.27e-188	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHOLMADN_00214	2.3e-173	-	-	-	S	-	-	-	Membrane
KHOLMADN_00215	1.52e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
KHOLMADN_00216	2.31e-110	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KHOLMADN_00217	5.06e-298	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
KHOLMADN_00219	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
KHOLMADN_00220	3.84e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KHOLMADN_00221	2.19e-270	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KHOLMADN_00222	5.45e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
KHOLMADN_00224	9.85e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KHOLMADN_00225	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
KHOLMADN_00226	5.45e-233	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
KHOLMADN_00227	5.65e-277	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
KHOLMADN_00228	3.29e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
KHOLMADN_00229	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KHOLMADN_00230	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHOLMADN_00231	7.25e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHOLMADN_00232	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHOLMADN_00233	1.18e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHOLMADN_00234	1.25e-76	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHOLMADN_00235	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHOLMADN_00236	9.39e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KHOLMADN_00237	1.1e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
KHOLMADN_00238	7.81e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
KHOLMADN_00239	9.94e-253	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
KHOLMADN_00240	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHOLMADN_00241	2.58e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHOLMADN_00242	4.59e-248	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KHOLMADN_00243	1.77e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHOLMADN_00244	4.39e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHOLMADN_00245	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
KHOLMADN_00246	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
KHOLMADN_00247	7.49e-181	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
KHOLMADN_00248	2.31e-63	-	-	-	-	-	-	-	-
KHOLMADN_00249	2.11e-200	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHOLMADN_00250	9.07e-146	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHOLMADN_00251	1.26e-243	ampC	-	-	V	-	-	-	Beta-lactamase
KHOLMADN_00252	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
KHOLMADN_00253	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00254	1.02e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
KHOLMADN_00255	3.24e-10	-	-	-	-	-	-	-	-
KHOLMADN_00257	1.55e-74	-	-	-	-	-	-	-	-
KHOLMADN_00259	2.13e-167	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
KHOLMADN_00260	4.49e-185	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHOLMADN_00261	7.54e-205	yvgN	-	-	S	-	-	-	Aldo keto reductase
KHOLMADN_00262	7.9e-153	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
KHOLMADN_00263	3.38e-109	-	-	-	K	-	-	-	GNAT family
KHOLMADN_00266	3.55e-123	-	-	-	-	-	-	-	-
KHOLMADN_00267	4.06e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
KHOLMADN_00268	1.44e-228	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
KHOLMADN_00270	2.12e-145	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
KHOLMADN_00273	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
KHOLMADN_00275	5.87e-239	-	-	-	EGP	-	-	-	Major Facilitator
KHOLMADN_00277	6.02e-68	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
KHOLMADN_00278	2.49e-73	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
KHOLMADN_00279	2.31e-56	-	-	-	S	-	-	-	Protein conserved in bacteria
KHOLMADN_00280	2.6e-124	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
KHOLMADN_00281	1.24e-57	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
KHOLMADN_00282	6.41e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
KHOLMADN_00283	4.53e-238	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHOLMADN_00284	4.9e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
KHOLMADN_00285	9.84e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHOLMADN_00286	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
KHOLMADN_00287	4.34e-198	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
KHOLMADN_00288	8.64e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KHOLMADN_00289	1.91e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHOLMADN_00290	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHOLMADN_00291	1.89e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00293	5.48e-70	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
KHOLMADN_00294	4.39e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
KHOLMADN_00295	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHOLMADN_00296	5.82e-277	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHOLMADN_00297	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHOLMADN_00298	9.05e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
KHOLMADN_00299	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHOLMADN_00300	1.17e-269	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KHOLMADN_00301	2.23e-11	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KHOLMADN_00302	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHOLMADN_00303	3.39e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
KHOLMADN_00304	1.63e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KHOLMADN_00305	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
KHOLMADN_00306	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
KHOLMADN_00307	1.34e-122	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
KHOLMADN_00308	4.62e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KHOLMADN_00309	5.91e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHOLMADN_00310	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
KHOLMADN_00311	1.08e-62	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
KHOLMADN_00312	1.04e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KHOLMADN_00313	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
KHOLMADN_00314	1.96e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
KHOLMADN_00315	2.57e-64	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
KHOLMADN_00316	4.97e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHOLMADN_00317	2.14e-123	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
KHOLMADN_00318	9.96e-212	-	-	-	L	-	-	-	PFAM Integrase catalytic region
KHOLMADN_00319	8.69e-98	-	-	-	-	-	-	-	-
KHOLMADN_00320	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
KHOLMADN_00321	9.87e-238	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
KHOLMADN_00322	2.39e-98	-	-	-	P	-	-	-	ArsC family
KHOLMADN_00323	3.13e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHOLMADN_00324	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KHOLMADN_00325	2.69e-158	-	-	-	S	-	-	-	repeat protein
KHOLMADN_00326	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
KHOLMADN_00327	3.62e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KHOLMADN_00328	0.0	-	-	-	S	-	-	-	amidohydrolase
KHOLMADN_00329	1.39e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KHOLMADN_00330	2.64e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
KHOLMADN_00331	3.8e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHOLMADN_00332	2.68e-08	-	-	-	-	-	-	-	-
KHOLMADN_00333	2.12e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
KHOLMADN_00334	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
KHOLMADN_00335	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHOLMADN_00337	3.58e-142	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
KHOLMADN_00338	4.13e-185	ylmH	-	-	S	-	-	-	S4 domain protein
KHOLMADN_00339	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
KHOLMADN_00340	1.5e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHOLMADN_00341	4.99e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHOLMADN_00342	7.72e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KHOLMADN_00343	7.09e-189	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KHOLMADN_00344	8.4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHOLMADN_00345	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHOLMADN_00346	5.43e-228	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHOLMADN_00347	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KHOLMADN_00348	1.06e-30	ftsL	-	-	D	-	-	-	Cell division protein FtsL
KHOLMADN_00349	8.91e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHOLMADN_00350	3.12e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
KHOLMADN_00351	9.82e-76	-	-	-	-	-	-	-	-
KHOLMADN_00352	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
KHOLMADN_00353	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KHOLMADN_00354	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHOLMADN_00355	5.1e-204	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
KHOLMADN_00356	5.17e-249	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
KHOLMADN_00357	3.12e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KHOLMADN_00358	7.8e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHOLMADN_00359	3.03e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
KHOLMADN_00360	1.58e-145	yjbH	-	-	Q	-	-	-	Thioredoxin
KHOLMADN_00361	9.03e-258	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KHOLMADN_00362	2.07e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KHOLMADN_00363	6.49e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KHOLMADN_00365	3.67e-05	-	-	-	S	-	-	-	Protein of unknown function DUF262
KHOLMADN_00371	1.88e-54	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
KHOLMADN_00372	2.4e-180	-	-	-	S	-	-	-	calcium ion binding
KHOLMADN_00373	9.69e-99	-	-	-	S	-	-	-	Single-strand binding protein family
KHOLMADN_00374	2.88e-218	-	-	-	S	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
KHOLMADN_00375	2.36e-224	-	-	-	S	-	-	-	DNA metabolic process
KHOLMADN_00384	7.82e-154	-	-	-	S	-	-	-	DNA binding
KHOLMADN_00385	7.18e-80	-	-	-	K	-	-	-	Peptidase S24-like
KHOLMADN_00386	1.46e-78	-	-	-	-	-	-	-	-
KHOLMADN_00387	3.71e-129	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
KHOLMADN_00388	3.76e-06	-	-	-	-	-	-	-	-
KHOLMADN_00389	2.26e-23	-	-	-	L	-	-	-	nuclease
KHOLMADN_00390	1.32e-47	-	-	-	-	-	-	-	-
KHOLMADN_00391	4.51e-260	-	-	-	S	-	-	-	Phage integrase family
KHOLMADN_00392	6.11e-118	-	-	-	S	-	-	-	Protein conserved in bacteria
KHOLMADN_00393	1.58e-224	-	-	-	-	-	-	-	-
KHOLMADN_00394	1.1e-200	-	-	-	-	-	-	-	-
KHOLMADN_00395	4.76e-19	-	-	-	-	-	-	-	-
KHOLMADN_00396	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KHOLMADN_00397	5.79e-217	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHOLMADN_00398	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
KHOLMADN_00399	1.7e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
KHOLMADN_00400	8.69e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
KHOLMADN_00401	4.99e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
KHOLMADN_00402	1.21e-134	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
KHOLMADN_00403	4.27e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHOLMADN_00404	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KHOLMADN_00405	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KHOLMADN_00406	0.0	-	-	-	S	-	-	-	membrane
KHOLMADN_00407	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHOLMADN_00408	2.93e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
KHOLMADN_00409	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHOLMADN_00410	2.58e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHOLMADN_00411	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KHOLMADN_00412	4.08e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KHOLMADN_00413	5.66e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHOLMADN_00414	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
KHOLMADN_00415	9.66e-198	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHOLMADN_00416	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHOLMADN_00417	1.8e-296	-	-	-	V	-	-	-	MatE
KHOLMADN_00418	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KHOLMADN_00419	5.62e-155	csrR	-	-	K	-	-	-	response regulator
KHOLMADN_00420	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
KHOLMADN_00421	9.71e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
KHOLMADN_00422	2.18e-269	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
KHOLMADN_00423	1.67e-171	yqeM	-	-	Q	-	-	-	Methyltransferase
KHOLMADN_00424	1.62e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHOLMADN_00425	2.63e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
KHOLMADN_00426	6.58e-120	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHOLMADN_00427	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
KHOLMADN_00428	6.3e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
KHOLMADN_00429	4.65e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
KHOLMADN_00430	1.55e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KHOLMADN_00431	5.12e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KHOLMADN_00432	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHOLMADN_00433	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
KHOLMADN_00434	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHOLMADN_00435	3.11e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
KHOLMADN_00436	3.15e-311	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
KHOLMADN_00437	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHOLMADN_00438	2.8e-135	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHOLMADN_00439	7.57e-208	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KHOLMADN_00440	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHOLMADN_00441	3.67e-175	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
KHOLMADN_00442	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KHOLMADN_00443	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KHOLMADN_00444	3.73e-151	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHOLMADN_00445	8.85e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
KHOLMADN_00446	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
KHOLMADN_00447	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHOLMADN_00448	5.8e-270	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KHOLMADN_00449	8.67e-170	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00450	1.23e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
KHOLMADN_00452	2.22e-190	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHOLMADN_00453	3.39e-226	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
KHOLMADN_00454	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
KHOLMADN_00455	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KHOLMADN_00456	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
KHOLMADN_00458	2.68e-50	-	-	-	-	-	-	-	-
KHOLMADN_00460	3.48e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
KHOLMADN_00461	7.57e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
KHOLMADN_00462	1.2e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KHOLMADN_00463	3.23e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
KHOLMADN_00464	4.35e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KHOLMADN_00465	2.44e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHOLMADN_00466	2.89e-152	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KHOLMADN_00467	1.06e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
KHOLMADN_00468	2.34e-141	-	-	-	-	-	-	-	-
KHOLMADN_00469	3.58e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
KHOLMADN_00470	4.25e-236	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHOLMADN_00471	1.87e-133	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
KHOLMADN_00472	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KHOLMADN_00473	1.01e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHOLMADN_00474	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KHOLMADN_00475	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHOLMADN_00476	1.96e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHOLMADN_00477	1.82e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
KHOLMADN_00478	6.43e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHOLMADN_00479	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHOLMADN_00480	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
KHOLMADN_00481	7.75e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
KHOLMADN_00482	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KHOLMADN_00483	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHOLMADN_00484	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KHOLMADN_00485	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KHOLMADN_00486	1.48e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHOLMADN_00487	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHOLMADN_00488	5.41e-47	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
KHOLMADN_00489	6.57e-107	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHOLMADN_00491	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHOLMADN_00492	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHOLMADN_00493	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHOLMADN_00494	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
KHOLMADN_00495	2.59e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHOLMADN_00496	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
KHOLMADN_00497	6.77e-247	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KHOLMADN_00498	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
KHOLMADN_00499	2.83e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHOLMADN_00500	4.7e-188	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
KHOLMADN_00501	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KHOLMADN_00502	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHOLMADN_00503	1.31e-218	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KHOLMADN_00504	1.17e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHOLMADN_00505	2.51e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
KHOLMADN_00506	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHOLMADN_00507	4.08e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
KHOLMADN_00508	2.33e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
KHOLMADN_00509	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
KHOLMADN_00510	1.67e-272	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
KHOLMADN_00511	2.1e-270	arcT	-	-	E	-	-	-	Aminotransferase
KHOLMADN_00512	6.55e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
KHOLMADN_00513	3.75e-141	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
KHOLMADN_00514	2.87e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHOLMADN_00516	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KHOLMADN_00517	4.1e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
KHOLMADN_00518	4.39e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHOLMADN_00519	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHOLMADN_00520	8.84e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
KHOLMADN_00521	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
KHOLMADN_00522	3.12e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KHOLMADN_00523	5.52e-91	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KHOLMADN_00524	6.55e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KHOLMADN_00525	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
KHOLMADN_00526	6.46e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHOLMADN_00527	1.1e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
KHOLMADN_00528	3.12e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
KHOLMADN_00529	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
KHOLMADN_00530	4.74e-221	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KHOLMADN_00531	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
KHOLMADN_00532	1.56e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHOLMADN_00533	1.15e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHOLMADN_00534	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHOLMADN_00535	0.0	ydaO	-	-	E	-	-	-	amino acid
KHOLMADN_00536	4.12e-50	-	-	-	-	-	-	-	-
KHOLMADN_00537	9.05e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
KHOLMADN_00538	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
KHOLMADN_00539	8.42e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
KHOLMADN_00540	4.45e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHOLMADN_00541	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHOLMADN_00542	2.5e-258	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHOLMADN_00543	2.31e-69	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
KHOLMADN_00544	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
KHOLMADN_00545	5.87e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHOLMADN_00546	1.31e-209	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHOLMADN_00547	5.26e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
KHOLMADN_00548	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KHOLMADN_00549	2.3e-50	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
KHOLMADN_00550	7.31e-163	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
KHOLMADN_00551	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
KHOLMADN_00552	1.76e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
KHOLMADN_00553	2.14e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHOLMADN_00554	1.46e-300	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
KHOLMADN_00555	9.38e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
KHOLMADN_00556	2e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
KHOLMADN_00557	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
KHOLMADN_00558	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
KHOLMADN_00559	3.15e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
KHOLMADN_00560	1.49e-225	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KHOLMADN_00561	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHOLMADN_00562	7.13e-276	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
KHOLMADN_00563	2.06e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHOLMADN_00564	2.65e-247	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
KHOLMADN_00565	8.24e-153	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KHOLMADN_00566	4.17e-96	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KHOLMADN_00567	4.48e-131	-	-	-	-	-	-	-	-
KHOLMADN_00568	3.39e-84	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHOLMADN_00569	8.14e-162	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHOLMADN_00570	7.56e-15	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
KHOLMADN_00571	3.55e-64	-	-	-	G	-	-	-	Major Facilitator Superfamily
KHOLMADN_00572	3.49e-133	-	-	-	G	-	-	-	Major Facilitator Superfamily
KHOLMADN_00574	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
KHOLMADN_00576	2.24e-196	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KHOLMADN_00577	7.06e-58	-	-	-	GM	-	-	-	NAD(P)H-binding
KHOLMADN_00578	6.38e-118	-	-	-	GM	-	-	-	NAD(P)H-binding
KHOLMADN_00579	3.44e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
KHOLMADN_00580	7.61e-299	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
KHOLMADN_00582	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
KHOLMADN_00583	9.13e-17	-	-	-	-	-	-	-	-
KHOLMADN_00584	3.96e-28	-	-	-	-	-	-	-	-
KHOLMADN_00585	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KHOLMADN_00587	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHOLMADN_00588	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
KHOLMADN_00589	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
KHOLMADN_00590	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KHOLMADN_00591	1.05e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KHOLMADN_00592	1.52e-300	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHOLMADN_00593	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHOLMADN_00594	7.37e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
KHOLMADN_00595	7.61e-203	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
KHOLMADN_00596	1.48e-270	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
KHOLMADN_00597	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
KHOLMADN_00598	3.63e-271	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
KHOLMADN_00599	1.07e-129	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
KHOLMADN_00600	3.23e-270	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KHOLMADN_00601	9.63e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
KHOLMADN_00602	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
KHOLMADN_00603	2.74e-272	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KHOLMADN_00604	2.59e-229	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
KHOLMADN_00605	4.69e-230	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
KHOLMADN_00606	2.45e-41	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
KHOLMADN_00607	5.16e-57	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
KHOLMADN_00608	2.99e-57	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
KHOLMADN_00609	1.86e-262	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
KHOLMADN_00610	3.09e-25	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
KHOLMADN_00611	1.77e-298	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
KHOLMADN_00612	9.46e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHOLMADN_00613	9.48e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KHOLMADN_00614	2.06e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
KHOLMADN_00615	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KHOLMADN_00616	7.11e-172	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
KHOLMADN_00617	1.97e-129	-	-	-	-	-	-	-	-
KHOLMADN_00618	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
KHOLMADN_00619	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
KHOLMADN_00620	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KHOLMADN_00621	2.03e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHOLMADN_00622	1.39e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHOLMADN_00623	9.61e-106	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
KHOLMADN_00624	1.15e-229	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KHOLMADN_00625	1.5e-85	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
KHOLMADN_00626	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
KHOLMADN_00627	1.26e-210	-	-	-	C	-	-	-	Aldo keto reductase
KHOLMADN_00628	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
KHOLMADN_00629	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KHOLMADN_00630	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHOLMADN_00631	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
KHOLMADN_00632	4.71e-47	-	-	-	-	-	-	-	-
KHOLMADN_00633	8.98e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KHOLMADN_00634	3.13e-228	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHOLMADN_00635	3.77e-176	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
KHOLMADN_00636	2.3e-26	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
KHOLMADN_00637	1.72e-243	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHOLMADN_00638	4.06e-140	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
KHOLMADN_00639	7.69e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
KHOLMADN_00640	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KHOLMADN_00641	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
KHOLMADN_00642	2.29e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
KHOLMADN_00643	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
KHOLMADN_00644	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHOLMADN_00645	1.92e-269	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
KHOLMADN_00646	4.51e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
KHOLMADN_00647	9.32e-182	yycI	-	-	S	-	-	-	YycH protein
KHOLMADN_00648	1.16e-302	yycH	-	-	S	-	-	-	YycH protein
KHOLMADN_00649	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KHOLMADN_00650	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KHOLMADN_00653	3.97e-64	-	-	-	-	-	-	-	-
KHOLMADN_00654	1.26e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
KHOLMADN_00655	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KHOLMADN_00656	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KHOLMADN_00657	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
KHOLMADN_00658	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHOLMADN_00659	1.7e-151	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KHOLMADN_00660	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KHOLMADN_00661	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHOLMADN_00662	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHOLMADN_00663	9.75e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHOLMADN_00664	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
KHOLMADN_00665	1.52e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHOLMADN_00666	3.8e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHOLMADN_00667	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
KHOLMADN_00668	5.32e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KHOLMADN_00669	1.43e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHOLMADN_00670	4.39e-189	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
KHOLMADN_00671	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHOLMADN_00672	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KHOLMADN_00673	1.33e-46	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KHOLMADN_00674	1.28e-237	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
KHOLMADN_00675	2.95e-133	-	-	-	NU	-	-	-	mannosyl-glycoprotein
KHOLMADN_00676	2.95e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KHOLMADN_00677	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
KHOLMADN_00678	1.46e-106	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KHOLMADN_00679	2.94e-54	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KHOLMADN_00680	1.04e-17	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KHOLMADN_00681	1.8e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
KHOLMADN_00682	3.58e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
KHOLMADN_00683	1.59e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KHOLMADN_00684	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
KHOLMADN_00685	2.38e-171	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
KHOLMADN_00686	4.45e-274	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
KHOLMADN_00687	7.77e-261	-	-	-	EGP	-	-	-	Major Facilitator
KHOLMADN_00688	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
KHOLMADN_00689	3.77e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KHOLMADN_00690	9.15e-194	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KHOLMADN_00692	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHOLMADN_00693	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
KHOLMADN_00694	6.25e-78	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KHOLMADN_00695	3.44e-198	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
KHOLMADN_00696	4.1e-48	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
KHOLMADN_00697	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
KHOLMADN_00698	2.29e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
KHOLMADN_00699	1.09e-62	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHOLMADN_00700	8.83e-99	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHOLMADN_00701	1.92e-60	cpg2	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
KHOLMADN_00702	5.66e-71	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
KHOLMADN_00703	1.01e-164	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
KHOLMADN_00704	1.69e-81	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHOLMADN_00705	1.19e-72	-	-	-	S	-	-	-	FMN_bind
KHOLMADN_00706	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00707	4.61e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLMADN_00708	8.67e-114	-	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHOLMADN_00710	1.1e-07	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
KHOLMADN_00711	4.42e-221	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
KHOLMADN_00712	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
KHOLMADN_00713	2.28e-133	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KHOLMADN_00714	3.13e-154	-	-	-	-	-	-	-	-
KHOLMADN_00716	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
KHOLMADN_00717	0.0	-	1.7.2.5	-	P	ko:K04561	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Cytochrome C and Quinol oxidase polypeptide I
KHOLMADN_00718	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KHOLMADN_00719	7.85e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
KHOLMADN_00720	1.16e-101	dltr	-	-	K	-	-	-	response regulator
KHOLMADN_00721	5.92e-164	sptS	-	-	T	-	-	-	Histidine kinase
KHOLMADN_00722	4.62e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KHOLMADN_00723	2.8e-135	-	-	-	K	-	-	-	acetyltransferase
KHOLMADN_00724	1.05e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
KHOLMADN_00725	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHOLMADN_00726	1.93e-204	-	-	-	EG	-	-	-	EamA-like transporter family
KHOLMADN_00727	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KHOLMADN_00728	1.45e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
KHOLMADN_00729	6.42e-154	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
KHOLMADN_00730	3.68e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHOLMADN_00731	5.96e-264	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KHOLMADN_00732	1.19e-171	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
KHOLMADN_00733	2.23e-73	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
KHOLMADN_00734	1.2e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KHOLMADN_00735	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KHOLMADN_00736	3.96e-274	-	-	-	G	-	-	-	Transporter, major facilitator family protein
KHOLMADN_00737	4.39e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KHOLMADN_00738	5.78e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KHOLMADN_00739	2.34e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
KHOLMADN_00740	8.61e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
KHOLMADN_00741	7.63e-230	-	-	-	K	-	-	-	WYL domain
KHOLMADN_00742	3.96e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
KHOLMADN_00743	3.18e-46	-	-	-	-	-	-	-	-
KHOLMADN_00746	5.35e-84	-	-	-	-	-	-	-	-
KHOLMADN_00747	1.36e-142	yicL	-	-	EG	-	-	-	EamA-like transporter family
KHOLMADN_00748	1.45e-107	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
KHOLMADN_00749	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KHOLMADN_00750	5.05e-210	-	-	-	K	-	-	-	LysR substrate binding domain
KHOLMADN_00751	9.52e-205	rssA	-	-	S	-	-	-	Phospholipase, patatin family
KHOLMADN_00752	6.03e-270	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
KHOLMADN_00753	5.79e-233	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
KHOLMADN_00754	2.06e-30	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KHOLMADN_00755	4.77e-116	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
KHOLMADN_00756	2.09e-243	flp	-	-	V	-	-	-	Beta-lactamase
KHOLMADN_00757	1.87e-289	-	-	-	-	-	-	-	-
KHOLMADN_00759	1.7e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KHOLMADN_00760	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHOLMADN_00761	1.85e-207	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
KHOLMADN_00762	8.78e-206	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KHOLMADN_00763	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KHOLMADN_00765	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
KHOLMADN_00767	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHOLMADN_00768	5.91e-299	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
KHOLMADN_00770	5.21e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
KHOLMADN_00771	6.9e-126	-	-	-	K	-	-	-	Virulence activator alpha C-term
KHOLMADN_00772	1.54e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
KHOLMADN_00774	8.99e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
KHOLMADN_00776	7.33e-184	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
KHOLMADN_00777	8.82e-51	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KHOLMADN_00778	8.47e-67	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KHOLMADN_00779	1.22e-32	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KHOLMADN_00780	1.65e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
KHOLMADN_00782	7.48e-301	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
KHOLMADN_00783	8.67e-44	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
KHOLMADN_00784	3.57e-117	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
KHOLMADN_00785	7.97e-41	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
KHOLMADN_00786	2.8e-96	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
KHOLMADN_00787	1.99e-95	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
KHOLMADN_00788	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
KHOLMADN_00789	3.26e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
KHOLMADN_00790	1.29e-196	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KHOLMADN_00791	7.42e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KHOLMADN_00792	0.0	-	-	-	L	-	-	-	DNA helicase
KHOLMADN_00793	7.63e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KHOLMADN_00794	3.57e-282	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
KHOLMADN_00795	5.3e-239	-	-	-	-	-	-	-	-
KHOLMADN_00796	8.66e-161	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
KHOLMADN_00797	2.27e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
KHOLMADN_00798	1.36e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
KHOLMADN_00799	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHOLMADN_00800	7.76e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
KHOLMADN_00801	3.77e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHOLMADN_00802	8.42e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHOLMADN_00803	9.13e-202	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHOLMADN_00804	7.82e-210	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KHOLMADN_00805	1.29e-119	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KHOLMADN_00806	2.31e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
KHOLMADN_00807	6.12e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
KHOLMADN_00808	2.72e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHOLMADN_00809	1.73e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHOLMADN_00810	2.88e-75	-	-	-	-	-	-	-	-
KHOLMADN_00811	1.37e-182	yidA	-	-	S	-	-	-	hydrolase
KHOLMADN_00812	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
KHOLMADN_00813	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
KHOLMADN_00814	7.45e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KHOLMADN_00815	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHOLMADN_00816	5.09e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHOLMADN_00817	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
KHOLMADN_00818	4.56e-62	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
KHOLMADN_00819	3.63e-83	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
KHOLMADN_00820	3.63e-156	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
KHOLMADN_00821	7.41e-61	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHOLMADN_00822	9.6e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KHOLMADN_00823	3.15e-201	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KHOLMADN_00824	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHOLMADN_00825	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KHOLMADN_00826	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHOLMADN_00827	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHOLMADN_00828	5.83e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
KHOLMADN_00829	4.51e-148	-	-	-	S	-	-	-	(CBS) domain
KHOLMADN_00830	3.8e-130	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHOLMADN_00831	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHOLMADN_00832	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
KHOLMADN_00833	1.19e-73	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
KHOLMADN_00834	4.54e-111	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
KHOLMADN_00835	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHOLMADN_00836	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHOLMADN_00837	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHOLMADN_00838	1.52e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHOLMADN_00839	1.07e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHOLMADN_00840	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KHOLMADN_00841	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHOLMADN_00842	2.52e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
KHOLMADN_00843	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHOLMADN_00844	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHOLMADN_00845	4.92e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHOLMADN_00846	6.46e-232	camS	-	-	S	-	-	-	sex pheromone
KHOLMADN_00847	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHOLMADN_00848	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KHOLMADN_00849	4.32e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHOLMADN_00850	3.74e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHOLMADN_00851	9.5e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
KHOLMADN_00852	4.28e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
KHOLMADN_00853	1.1e-258	-	-	-	S	-	-	-	interspecies interaction between organisms
KHOLMADN_00854	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KHOLMADN_00855	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHOLMADN_00856	2.6e-184	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHOLMADN_00857	2.37e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHOLMADN_00858	2.06e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHOLMADN_00859	2.39e-190	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHOLMADN_00860	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
KHOLMADN_00861	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHOLMADN_00862	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHOLMADN_00863	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHOLMADN_00864	2.6e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
KHOLMADN_00865	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHOLMADN_00866	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHOLMADN_00867	1.84e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHOLMADN_00868	4.09e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KHOLMADN_00869	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
KHOLMADN_00870	2.08e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHOLMADN_00871	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHOLMADN_00872	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHOLMADN_00873	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHOLMADN_00874	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHOLMADN_00875	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHOLMADN_00876	1.5e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHOLMADN_00877	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHOLMADN_00878	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHOLMADN_00879	1.11e-37	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KHOLMADN_00880	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHOLMADN_00881	2.49e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHOLMADN_00882	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHOLMADN_00883	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHOLMADN_00884	1.35e-202	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHOLMADN_00885	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHOLMADN_00886	3.16e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KHOLMADN_00887	3.41e-152	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHOLMADN_00888	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KHOLMADN_00889	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHOLMADN_00890	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHOLMADN_00891	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHOLMADN_00892	1.77e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
KHOLMADN_00893	6.09e-275	-	-	-	-	-	-	-	-
KHOLMADN_00894	2.4e-172	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
KHOLMADN_00895	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHOLMADN_00896	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHOLMADN_00897	8.51e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLMADN_00898	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHOLMADN_00899	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
KHOLMADN_00901	1.12e-94	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KHOLMADN_00902	1.7e-262	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KHOLMADN_00903	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
KHOLMADN_00904	8.07e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHOLMADN_00905	2e-206	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHOLMADN_00906	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHOLMADN_00907	3.3e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHOLMADN_00908	2.81e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KHOLMADN_00909	1.14e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
KHOLMADN_00910	5.75e-98	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KHOLMADN_00911	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KHOLMADN_00913	8.46e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KHOLMADN_00914	1.9e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHOLMADN_00915	1.7e-281	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHOLMADN_00916	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHOLMADN_00917	7.64e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHOLMADN_00918	1.29e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHOLMADN_00919	7.64e-166	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
KHOLMADN_00920	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KHOLMADN_00921	5.11e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KHOLMADN_00922	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
KHOLMADN_00923	9.12e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
KHOLMADN_00924	1e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
KHOLMADN_00925	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KHOLMADN_00926	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
KHOLMADN_00927	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHOLMADN_00928	1.04e-213	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KHOLMADN_00929	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHOLMADN_00930	5.67e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHOLMADN_00931	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KHOLMADN_00932	3.22e-254	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHOLMADN_00933	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHOLMADN_00934	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHOLMADN_00936	5.46e-135	-	-	-	-	-	-	-	-
KHOLMADN_00937	1.24e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
KHOLMADN_00938	3.3e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KHOLMADN_00939	4.79e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KHOLMADN_00940	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
KHOLMADN_00941	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHOLMADN_00942	1.32e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KHOLMADN_00943	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KHOLMADN_00944	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
KHOLMADN_00945	3.07e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHOLMADN_00946	1.29e-181	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KHOLMADN_00947	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
KHOLMADN_00948	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHOLMADN_00949	6.93e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
KHOLMADN_00950	2.79e-115	-	-	-	GM	-	-	-	epimerase
KHOLMADN_00951	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
KHOLMADN_00952	4.33e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
KHOLMADN_00953	1.81e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
KHOLMADN_00954	2.08e-265	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
KHOLMADN_00955	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHOLMADN_00956	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHOLMADN_00957	6.11e-106	usp5	-	-	T	-	-	-	universal stress protein
KHOLMADN_00958	6.2e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
KHOLMADN_00959	5.95e-23	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHOLMADN_00960	9.33e-91	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHOLMADN_00961	2.45e-222	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KHOLMADN_00962	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
KHOLMADN_00963	1.29e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHOLMADN_00964	6.15e-161	-	-	-	S	-	-	-	Membrane
KHOLMADN_00965	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KHOLMADN_00966	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
KHOLMADN_00967	2.49e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KHOLMADN_00968	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
KHOLMADN_00969	1.71e-284	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHOLMADN_00970	7.74e-231	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KHOLMADN_00971	6.55e-183	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KHOLMADN_00972	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
KHOLMADN_00973	1.21e-48	-	-	-	-	-	-	-	-
KHOLMADN_00974	3.97e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_00975	1.01e-153	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLMADN_00976	8.93e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KHOLMADN_00977	9.08e-71	-	-	-	-	-	-	-	-
KHOLMADN_00978	4.73e-214	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHOLMADN_00979	9.63e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHOLMADN_00980	1.02e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
KHOLMADN_00981	1.16e-118	ymdB	-	-	S	-	-	-	Macro domain protein
KHOLMADN_00982	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KHOLMADN_00983	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KHOLMADN_00984	5.76e-59	-	-	-	-	-	-	-	-
KHOLMADN_00985	4.63e-266	-	-	-	S	-	-	-	Putative metallopeptidase domain
KHOLMADN_00986	3.7e-259	-	-	-	S	-	-	-	associated with various cellular activities
KHOLMADN_00987	8.13e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
KHOLMADN_00988	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
KHOLMADN_00990	5.24e-158	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
KHOLMADN_00991	3.05e-73	-	-	-	-	-	-	-	-
KHOLMADN_00992	1.76e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KHOLMADN_00993	9.3e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHOLMADN_00994	4.44e-134	-	-	-	-	-	-	-	-
KHOLMADN_00995	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
KHOLMADN_00996	1.5e-254	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
KHOLMADN_00997	6.57e-244	arcT	-	-	E	-	-	-	Dipeptidase
KHOLMADN_00998	4.48e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
KHOLMADN_00999	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
KHOLMADN_01000	8.65e-271	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
KHOLMADN_01001	0.0	fusA1	-	-	J	-	-	-	elongation factor G
KHOLMADN_01002	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KHOLMADN_01003	2.18e-144	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
KHOLMADN_01004	5.72e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KHOLMADN_01005	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
KHOLMADN_01006	2.7e-204	-	-	-	EG	-	-	-	EamA-like transporter family
KHOLMADN_01007	7.83e-242	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
KHOLMADN_01008	5.43e-190	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
KHOLMADN_01009	2.4e-172	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
KHOLMADN_01010	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
KHOLMADN_01011	1.91e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
KHOLMADN_01012	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KHOLMADN_01013	5.33e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
KHOLMADN_01014	8.67e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
KHOLMADN_01015	9.62e-270	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
KHOLMADN_01016	6.91e-259	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KHOLMADN_01017	7.88e-119	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KHOLMADN_01018	2e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
KHOLMADN_01019	1.65e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
KHOLMADN_01020	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
KHOLMADN_01021	7.22e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
KHOLMADN_01022	1.08e-112	-	-	-	K	-	-	-	FR47-like protein
KHOLMADN_01023	5.02e-44	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KHOLMADN_01024	4.67e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF998)
KHOLMADN_01025	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
KHOLMADN_01027	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KHOLMADN_01028	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KHOLMADN_01029	2.16e-26	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
KHOLMADN_01030	3.82e-23	-	-	-	-	-	-	-	-
KHOLMADN_01031	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHOLMADN_01032	4.22e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
KHOLMADN_01033	8.38e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHOLMADN_01034	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHOLMADN_01035	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
KHOLMADN_01036	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KHOLMADN_01037	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KHOLMADN_01038	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KHOLMADN_01039	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHOLMADN_01040	2.02e-140	-	-	-	-	-	-	-	-
KHOLMADN_01041	1.07e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHOLMADN_01042	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
KHOLMADN_01043	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
KHOLMADN_01044	1.11e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KHOLMADN_01045	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KHOLMADN_01046	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
KHOLMADN_01047	2.67e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHOLMADN_01048	1.14e-149	ybbR	-	-	S	-	-	-	YbbR-like protein
KHOLMADN_01049	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHOLMADN_01050	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHOLMADN_01051	2.55e-68	-	-	-	-	-	-	-	-
KHOLMADN_01052	1.36e-261	oatA	-	-	I	-	-	-	Acyltransferase
KHOLMADN_01053	1.44e-191	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KHOLMADN_01054	3.3e-106	lytE	-	-	M	-	-	-	Lysin motif
KHOLMADN_01055	1.64e-220	-	-	-	S	-	-	-	Conserved hypothetical protein 698
KHOLMADN_01056	1.36e-212	-	-	-	K	-	-	-	LysR substrate binding domain
KHOLMADN_01057	1.35e-164	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KHOLMADN_01058	2.58e-190	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
KHOLMADN_01059	1.46e-115	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
KHOLMADN_01060	2.9e-63	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
KHOLMADN_01061	3.38e-137	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
KHOLMADN_01062	2.22e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KHOLMADN_01063	1.95e-163	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
KHOLMADN_01064	3.23e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
KHOLMADN_01065	7.33e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
KHOLMADN_01067	2.77e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
KHOLMADN_01068	5.09e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHOLMADN_01069	1.62e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
KHOLMADN_01070	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
KHOLMADN_01071	2.94e-148	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
KHOLMADN_01072	4.63e-174	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
KHOLMADN_01073	8.95e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
KHOLMADN_01074	1.74e-178	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KHOLMADN_01075	5.63e-196	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHOLMADN_01076	1.61e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KHOLMADN_01077	5.35e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHOLMADN_01078	1.23e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHOLMADN_01079	1.66e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
KHOLMADN_01080	6.87e-295	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
KHOLMADN_01081	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHOLMADN_01082	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHOLMADN_01083	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
KHOLMADN_01084	3.87e-282	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KHOLMADN_01085	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
KHOLMADN_01086	3.19e-66	ylxQ	-	-	J	-	-	-	ribosomal protein
KHOLMADN_01087	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHOLMADN_01088	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHOLMADN_01089	3.22e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHOLMADN_01090	1.69e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KHOLMADN_01091	9.07e-313	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
KHOLMADN_01092	3.04e-66	-	-	-	IQ	ko:K18333	ko00051,ko01120,map00051,map01120	ko00000,ko00001	KR domain
KHOLMADN_01093	2.07e-24	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
KHOLMADN_01094	1.13e-125	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KHOLMADN_01095	5.19e-83	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KHOLMADN_01096	2.54e-287	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
KHOLMADN_01098	6.73e-86	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
KHOLMADN_01099	2.36e-222	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
KHOLMADN_01100	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KHOLMADN_01101	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
KHOLMADN_01102	7.76e-146	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KHOLMADN_01103	2.92e-245	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
KHOLMADN_01105	4.71e-96	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
KHOLMADN_01106	5.51e-116	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
KHOLMADN_01107	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
KHOLMADN_01108	7.65e-39	-	-	-	S	ko:K08987	-	ko00000	membrane
KHOLMADN_01109	3.68e-67	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
KHOLMADN_01110	6.27e-68	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
KHOLMADN_01111	1.28e-132	-	-	-	Q	-	-	-	Methyltransferase domain
KHOLMADN_01113	3.19e-132	-	-	-	S	-	-	-	CAAX protease self-immunity
KHOLMADN_01114	1.29e-120	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHOLMADN_01115	2.11e-171	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KHOLMADN_01117	2.29e-18	-	-	-	K	-	-	-	Transcriptional regulator
KHOLMADN_01118	3.27e-129	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KHOLMADN_01119	2.67e-274	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KHOLMADN_01120	1.17e-131	-	-	-	-	-	-	-	-
KHOLMADN_01121	2.41e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
KHOLMADN_01122	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
KHOLMADN_01123	1.01e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
KHOLMADN_01124	1.95e-175	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KHOLMADN_01125	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KHOLMADN_01126	4.51e-206	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KHOLMADN_01127	1.8e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
KHOLMADN_01128	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
KHOLMADN_01129	7.29e-242	mocA	-	-	S	-	-	-	Oxidoreductase
KHOLMADN_01130	4.79e-307	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
KHOLMADN_01132	2.78e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
KHOLMADN_01133	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
KHOLMADN_01134	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
KHOLMADN_01135	1.65e-291	XK27_08315	-	-	M	-	-	-	Sulfatase
KHOLMADN_01136	2.42e-52	-	-	-	L	-	-	-	MULE transposase domain
KHOLMADN_01137	2.8e-189	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
KHOLMADN_01138	3.65e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
KHOLMADN_01139	2e-129	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KHOLMADN_01141	9.05e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHOLMADN_01142	8.01e-174	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
KHOLMADN_01143	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHOLMADN_01144	4.3e-311	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
KHOLMADN_01145	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
KHOLMADN_01147	7.24e-97	uspA3	-	-	T	-	-	-	universal stress protein
KHOLMADN_01148	3.62e-77	-	-	-	-	-	-	-	-
KHOLMADN_01149	4.83e-10	-	-	-	-	-	-	-	-
KHOLMADN_01150	1.84e-201	-	-	-	-	-	-	-	-
KHOLMADN_01151	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
KHOLMADN_01152	9.06e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KHOLMADN_01153	9.46e-96	-	-	-	O	-	-	-	OsmC-like protein
KHOLMADN_01154	4.46e-238	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
KHOLMADN_01155	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KHOLMADN_01156	3.57e-22	-	-	-	-	-	-	-	-
KHOLMADN_01157	1.44e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
KHOLMADN_01158	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_01159	1.12e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
KHOLMADN_01160	2.8e-230	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
KHOLMADN_01161	1.24e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KHOLMADN_01162	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
KHOLMADN_01163	3.19e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
KHOLMADN_01164	2.3e-129	dpsB	-	-	P	-	-	-	Belongs to the Dps family
KHOLMADN_01165	7.69e-142	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
KHOLMADN_01166	1.51e-40	-	-	-	-	-	-	-	-
KHOLMADN_01167	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHOLMADN_01168	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
KHOLMADN_01169	3.25e-191	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
KHOLMADN_01170	7.52e-300	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
KHOLMADN_01171	1.26e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KHOLMADN_01172	1.53e-210	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KHOLMADN_01173	3.51e-183	yceF	-	-	P	ko:K05794	-	ko00000	membrane
KHOLMADN_01174	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KHOLMADN_01175	1.79e-71	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
KHOLMADN_01176	7.77e-204	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
KHOLMADN_01177	4.01e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KHOLMADN_01178	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
KHOLMADN_01179	1e-215	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KHOLMADN_01181	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHOLMADN_01182	1.78e-167	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
KHOLMADN_01183	1.36e-136	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
KHOLMADN_01184	6.44e-240	-	-	-	I	-	-	-	Alpha beta
KHOLMADN_01185	4.01e-154	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
KHOLMADN_01186	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
KHOLMADN_01187	2.63e-208	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
KHOLMADN_01188	7.76e-188	-	-	-	I	-	-	-	Alpha/beta hydrolase family
KHOLMADN_01189	0.0	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KHOLMADN_01190	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
KHOLMADN_01191	7.54e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
KHOLMADN_01192	3.93e-60	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
KHOLMADN_01193	1.61e-250	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KHOLMADN_01194	1.21e-266	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
KHOLMADN_01195	3e-223	citR	-	-	K	-	-	-	sugar-binding domain protein
KHOLMADN_01196	3.03e-312	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KHOLMADN_01197	5.68e-211	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KHOLMADN_01198	1.58e-314	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KHOLMADN_01199	5.36e-282	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KHOLMADN_01200	2.48e-117	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KHOLMADN_01201	4.64e-235	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
KHOLMADN_01202	1.26e-288	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
KHOLMADN_01203	1.37e-99	mleR	-	-	K	-	-	-	LysR family
KHOLMADN_01204	1.16e-307	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
KHOLMADN_01205	2.35e-119	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
KHOLMADN_01206	4.61e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KHOLMADN_01207	1.66e-215	-	-	-	-	-	-	-	-
KHOLMADN_01208	4.69e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
KHOLMADN_01209	4.22e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
KHOLMADN_01210	3.22e-135	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
KHOLMADN_01211	8.63e-93	-	-	-	F	-	-	-	Nudix hydrolase
KHOLMADN_01212	2.84e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
KHOLMADN_01213	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KHOLMADN_01214	1.58e-226	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KHOLMADN_01215	3.29e-146	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
KHOLMADN_01216	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
KHOLMADN_01217	6.91e-234	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
KHOLMADN_01218	4.22e-214	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
KHOLMADN_01219	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHOLMADN_01220	6.63e-94	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
KHOLMADN_01221	1.18e-140	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
KHOLMADN_01223	1.57e-260	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
KHOLMADN_01224	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
KHOLMADN_01225	5.66e-231	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
KHOLMADN_01226	3.76e-193	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KHOLMADN_01227	1.6e-171	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_01229	4.39e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
KHOLMADN_01230	1.02e-295	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
KHOLMADN_01231	6.52e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
KHOLMADN_01232	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
KHOLMADN_01233	1.54e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHOLMADN_01234	1.13e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
KHOLMADN_01235	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHOLMADN_01236	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHOLMADN_01237	7.75e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHOLMADN_01238	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHOLMADN_01239	1.51e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
KHOLMADN_01240	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
KHOLMADN_01241	1.33e-219	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
KHOLMADN_01242	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHOLMADN_01243	4.81e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHOLMADN_01244	6.79e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHOLMADN_01245	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
KHOLMADN_01246	1.41e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
KHOLMADN_01247	9.93e-17	-	-	-	K	-	-	-	transcriptional regulator
KHOLMADN_01248	4.62e-288	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KHOLMADN_01249	2.68e-130	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
KHOLMADN_01250	4.31e-76	-	-	-	S	-	-	-	branched-chain amino acid
KHOLMADN_01251	6.89e-177	-	-	-	E	-	-	-	AzlC protein
KHOLMADN_01252	2.83e-261	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KHOLMADN_01253	4.91e-264	hpk31	-	-	T	-	-	-	Histidine kinase
KHOLMADN_01254	1.68e-155	vanR	-	-	K	-	-	-	response regulator
KHOLMADN_01255	7.97e-77	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
KHOLMADN_01258	1.41e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KHOLMADN_01259	5.43e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHOLMADN_01260	4.59e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KHOLMADN_01261	1.07e-203	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHOLMADN_01262	1.29e-190	-	-	-	S	-	-	-	HNH endonuclease
KHOLMADN_01263	2.43e-100	-	-	-	S	-	-	-	Phage terminase, small subunit
KHOLMADN_01264	0.0	-	-	-	S	-	-	-	Phage Terminase
KHOLMADN_01266	7.8e-300	-	-	-	S	-	-	-	Phage portal protein
KHOLMADN_01267	6.88e-87	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
KHOLMADN_01268	6.31e-254	-	-	-	S	-	-	-	peptidase activity
KHOLMADN_01269	4.29e-64	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KHOLMADN_01270	1.26e-29	-	-	-	S	-	-	-	Phage head-tail joining protein
KHOLMADN_01271	2.49e-49	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
KHOLMADN_01272	1.9e-54	-	-	-	-	-	-	-	-
KHOLMADN_01273	4.54e-144	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
KHOLMADN_01275	2.14e-19	-	-	-	-	-	-	-	-
KHOLMADN_01276	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
KHOLMADN_01277	3.77e-201	-	-	-	S	-	-	-	Phage tail protein
KHOLMADN_01278	4.34e-135	-	-	-	M	-	-	-	Prophage endopeptidase tail
KHOLMADN_01279	4.81e-47	spoIVFA	-	GT2,GT4	D	ko:K05802,ko:K06401,ko:K20444,ko:K22051	-	ko00000,ko01000,ko01005,ko02000	peptidase
KHOLMADN_01283	1.47e-69	-	-	-	-	-	-	-	-
KHOLMADN_01286	2.37e-33	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
KHOLMADN_01287	4.37e-258	-	-	-	S	-	-	-	peptidoglycan catabolic process
KHOLMADN_01289	1.76e-146	-	-	-	K	-	-	-	Transcriptional regulator
KHOLMADN_01290	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KHOLMADN_01291	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
KHOLMADN_01292	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
KHOLMADN_01293	1.44e-79	-	-	-	M	-	-	-	Glycosyl transferase 4-like
KHOLMADN_01294	8.42e-114	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
KHOLMADN_01295	1.88e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
KHOLMADN_01296	7.37e-148	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
KHOLMADN_01297	8.81e-166	epsB	-	-	M	-	-	-	biosynthesis protein
KHOLMADN_01298	2.08e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KHOLMADN_01299	9.9e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHOLMADN_01300	2.03e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
KHOLMADN_01301	3.53e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHOLMADN_01302	1.78e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
KHOLMADN_01303	5.29e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KHOLMADN_01304	6.65e-209	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KHOLMADN_01305	3.53e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
KHOLMADN_01306	5.42e-184	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
KHOLMADN_01307	2.1e-270	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
KHOLMADN_01308	4.55e-315	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KHOLMADN_01309	9.02e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_01310	5.16e-284	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KHOLMADN_01312	2.84e-239	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KHOLMADN_01314	4.3e-314	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHOLMADN_01315	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
KHOLMADN_01316	5.01e-276	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KHOLMADN_01317	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
KHOLMADN_01318	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHOLMADN_01319	4.68e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KHOLMADN_01320	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
KHOLMADN_01321	9.16e-105	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
KHOLMADN_01323	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
KHOLMADN_01324	3.07e-239	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
KHOLMADN_01325	4.16e-211	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
KHOLMADN_01326	3.86e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHOLMADN_01327	7.3e-212	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KHOLMADN_01328	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KHOLMADN_01329	3.45e-144	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
KHOLMADN_01330	1.03e-142	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHOLMADN_01331	7.63e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
KHOLMADN_01332	3.27e-123	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
KHOLMADN_01333	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHOLMADN_01334	1.3e-262	yacL	-	-	S	-	-	-	domain protein
KHOLMADN_01335	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHOLMADN_01336	3.92e-129	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
KHOLMADN_01337	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KHOLMADN_01338	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHOLMADN_01339	3.52e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHOLMADN_01340	1.2e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHOLMADN_01341	2.06e-282	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
KHOLMADN_01342	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KHOLMADN_01343	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHOLMADN_01344	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHOLMADN_01345	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KHOLMADN_01346	9.48e-204	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
KHOLMADN_01347	3.36e-110	-	-	-	L	-	-	-	nuclease
KHOLMADN_01348	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHOLMADN_01349	1.96e-52	-	-	-	-	-	-	-	-
KHOLMADN_01350	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KHOLMADN_01351	6.45e-240	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
KHOLMADN_01352	2.16e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLMADN_01353	2.34e-208	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLMADN_01354	2.38e-157	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_01355	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KHOLMADN_01356	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
KHOLMADN_01357	3.57e-289	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHOLMADN_01358	1.43e-66	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
KHOLMADN_01359	8.05e-136	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
KHOLMADN_01360	9.16e-35	-	-	-	-	-	-	-	-
KHOLMADN_01361	1.51e-97	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
KHOLMADN_01362	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KHOLMADN_01363	1.11e-208	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
KHOLMADN_01364	3.55e-172	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KHOLMADN_01366	1.31e-212	-	-	-	H	-	-	-	geranyltranstransferase activity
KHOLMADN_01367	1.89e-41	-	-	-	-	-	-	-	-
KHOLMADN_01368	3.92e-83	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
KHOLMADN_01369	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KHOLMADN_01370	6.63e-122	-	-	-	V	-	-	-	VanZ like family
KHOLMADN_01371	1.4e-282	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
KHOLMADN_01372	4.56e-80	-	-	-	-	-	-	-	-
KHOLMADN_01373	5.43e-231	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
KHOLMADN_01374	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
KHOLMADN_01375	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
KHOLMADN_01376	2.76e-218	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
KHOLMADN_01378	8.32e-109	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHOLMADN_01380	6.95e-105	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
KHOLMADN_01381	1.31e-53	-	-	-	-	-	-	-	-
KHOLMADN_01382	1.48e-218	-	-	-	GK	-	-	-	ROK family
KHOLMADN_01383	4.12e-164	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
KHOLMADN_01384	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
KHOLMADN_01385	3.13e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KHOLMADN_01386	7.21e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHOLMADN_01387	1.73e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHOLMADN_01388	6.33e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHOLMADN_01389	1.87e-101	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KHOLMADN_01390	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KHOLMADN_01391	4.03e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
KHOLMADN_01392	3.06e-203	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KHOLMADN_01393	2.21e-255	-	-	-	-	-	-	-	-
KHOLMADN_01394	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHOLMADN_01395	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHOLMADN_01397	4.16e-144	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
KHOLMADN_01398	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KHOLMADN_01399	6.64e-173	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KHOLMADN_01400	2.76e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KHOLMADN_01401	2.39e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
KHOLMADN_01402	3.08e-125	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KHOLMADN_01403	1.08e-64	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KHOLMADN_01404	1.34e-197	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
KHOLMADN_01405	4.74e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHOLMADN_01406	2.51e-98	yphH	-	-	S	-	-	-	Cupin domain
KHOLMADN_01407	1.78e-240	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHOLMADN_01408	1.47e-287	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KHOLMADN_01409	3.56e-187	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
KHOLMADN_01410	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
KHOLMADN_01411	8.2e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
KHOLMADN_01412	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
KHOLMADN_01413	3.25e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHOLMADN_01414	9.22e-37	-	-	-	S	-	-	-	Domain of unknown function DUF302
KHOLMADN_01415	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KHOLMADN_01416	9.88e-57	-	-	-	-	-	-	-	-
KHOLMADN_01417	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KHOLMADN_01418	6.62e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
KHOLMADN_01419	4.39e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHOLMADN_01420	4.23e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHOLMADN_01421	1.26e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHOLMADN_01422	5.67e-65	-	-	-	-	-	-	-	-
KHOLMADN_01423	1.06e-123	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
KHOLMADN_01424	0.0	-	-	-	EGP	-	-	-	Major Facilitator
KHOLMADN_01425	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
KHOLMADN_01426	2.23e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KHOLMADN_01427	3.91e-31	-	-	-	-	-	-	-	-
KHOLMADN_01430	8.17e-67	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
KHOLMADN_01431	4.14e-09	-	-	-	-	-	-	-	-
KHOLMADN_01432	6.59e-204	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
KHOLMADN_01433	5.97e-219	yueF	-	-	S	-	-	-	AI-2E family transporter
KHOLMADN_01435	3.3e-122	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KHOLMADN_01436	5.18e-210	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
KHOLMADN_01437	2.3e-239	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KHOLMADN_01438	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHOLMADN_01439	9.97e-95	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
KHOLMADN_01440	9.92e-26	-	-	-	S	-	-	-	Glycosyltransferase like family 2
KHOLMADN_01441	6.44e-129	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
KHOLMADN_01442	8.52e-216	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHOLMADN_01443	2.08e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
KHOLMADN_01444	7.78e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_01446	1.37e-300	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KHOLMADN_01447	1.21e-89	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
KHOLMADN_01448	2.4e-314	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KHOLMADN_01449	1.24e-130	-	-	-	K	-	-	-	DNA-templated transcription, initiation
KHOLMADN_01451	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
KHOLMADN_01452	6.59e-76	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
KHOLMADN_01455	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KHOLMADN_01456	3.7e-148	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLMADN_01457	1.79e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
KHOLMADN_01458	1.41e-114	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
KHOLMADN_01459	4.06e-58	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
KHOLMADN_01460	5.54e-144	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KHOLMADN_01461	1.89e-74	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
KHOLMADN_01463	5.5e-80	-	-	-	-	-	-	-	-
KHOLMADN_01464	1.16e-242	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHOLMADN_01465	9.76e-87	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHOLMADN_01466	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KHOLMADN_01467	1.63e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHOLMADN_01468	5.8e-124	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHOLMADN_01469	8.58e-146	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KHOLMADN_01470	9.18e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHOLMADN_01471	6.21e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
KHOLMADN_01472	6.35e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHOLMADN_01473	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHOLMADN_01475	1.56e-137	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
KHOLMADN_01476	3.35e-134	-	-	-	C	-	-	-	aldo keto reductase
KHOLMADN_01477	2.8e-256	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHOLMADN_01478	6.36e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHOLMADN_01479	4.47e-113	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
KHOLMADN_01480	1.4e-27	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
KHOLMADN_01481	7.32e-247	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
KHOLMADN_01482	1.66e-305	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KHOLMADN_01483	5.87e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KHOLMADN_01484	1.06e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
KHOLMADN_01485	5.99e-67	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHOLMADN_01486	1.32e-91	-	-	-	-	-	-	-	-
KHOLMADN_01487	1.26e-271	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KHOLMADN_01488	1.4e-236	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
KHOLMADN_01489	1.34e-179	-	-	-	-	-	-	-	-
KHOLMADN_01490	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
KHOLMADN_01491	2.23e-121	-	-	-	M	-	-	-	PFAM NLP P60 protein
KHOLMADN_01492	4.22e-299	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
KHOLMADN_01493	7.99e-126	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
KHOLMADN_01494	2.12e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
KHOLMADN_01495	2.49e-211	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
KHOLMADN_01496	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
KHOLMADN_01501	1.02e-201	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
KHOLMADN_01502	6.46e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHOLMADN_01503	1.11e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KHOLMADN_01504	1.34e-126	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
KHOLMADN_01505	1.18e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KHOLMADN_01506	1.35e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
KHOLMADN_01507	6.53e-139	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
KHOLMADN_01508	1.34e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
KHOLMADN_01509	1.13e-226	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHOLMADN_01510	2.58e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KHOLMADN_01511	1.27e-290	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KHOLMADN_01512	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHOLMADN_01513	2.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
KHOLMADN_01514	5.36e-07	-	-	-	-	-	-	-	-
KHOLMADN_01515	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KHOLMADN_01516	6.85e-164	-	-	-	F	-	-	-	NUDIX domain
KHOLMADN_01517	7.08e-142	pncA	-	-	Q	-	-	-	Isochorismatase family
KHOLMADN_01518	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHOLMADN_01519	3.84e-124	-	-	-	S	-	-	-	Pfam:DUF3816
KHOLMADN_01520	3.72e-83	-	-	-	L	-	-	-	Resolvase, N-terminal domain
KHOLMADN_01521	3.01e-116	-	-	-	L	-	-	-	Probable transposase
KHOLMADN_01522	7.8e-181	-	-	-	G	-	-	-	MucBP domain
KHOLMADN_01523	7.22e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHOLMADN_01524	6.05e-206	-	-	-	EG	-	-	-	EamA-like transporter family
KHOLMADN_01525	6.84e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
KHOLMADN_01526	4.62e-210	-	-	-	L	-	-	-	Z1 domain
KHOLMADN_01527	1.05e-149	-	-	-	-	-	-	-	-
KHOLMADN_01528	3.13e-49	-	-	-	-	-	-	-	-
KHOLMADN_01529	5.22e-88	-	-	-	-	-	-	-	-
KHOLMADN_01531	4.52e-176	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
KHOLMADN_01532	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
KHOLMADN_01533	7.63e-72	-	-	-	S	-	-	-	MazG-like family
KHOLMADN_01534	1.47e-136	-	-	-	I	-	-	-	PAP2 superfamily
KHOLMADN_01535	1.11e-94	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
KHOLMADN_01536	1.28e-46	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
KHOLMADN_01537	2.11e-31	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
KHOLMADN_01538	5.84e-123	-	-	-	-	-	-	-	-
KHOLMADN_01539	2e-284	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KHOLMADN_01540	1.06e-207	-	-	-	V	-	-	-	Beta-lactamase enzyme family
KHOLMADN_01541	0.0	potE	-	-	E	-	-	-	Amino Acid
KHOLMADN_01542	3.7e-139	-	-	-	S	-	-	-	VIT family
KHOLMADN_01543	7.13e-110	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
KHOLMADN_01544	1.18e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
KHOLMADN_01545	8.89e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KHOLMADN_01546	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHOLMADN_01547	1.35e-76	-	-	-	-	-	-	-	-
KHOLMADN_01548	1.49e-91	-	-	-	K	-	-	-	MerR HTH family regulatory protein
KHOLMADN_01549	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
KHOLMADN_01550	6.43e-148	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
KHOLMADN_01551	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
KHOLMADN_01552	3.52e-160	-	-	-	K	-	-	-	transcriptional regulator, ArsR family
KHOLMADN_01553	2.44e-217	abf	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
KHOLMADN_01554	1.62e-215	lacY	-	-	G	ko:K02532	-	ko00000,ko02000	Oligosaccharide H symporter
KHOLMADN_01555	6.08e-85	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
KHOLMADN_01556	3.75e-275	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
KHOLMADN_01557	3.14e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
KHOLMADN_01558	5.17e-93	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
KHOLMADN_01559	2.47e-106	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
KHOLMADN_01560	5.44e-89	-	-	-	-	-	-	-	-
KHOLMADN_01561	8.2e-81	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
KHOLMADN_01562	2.23e-47	-	-	-	M	-	-	-	biosynthesis protein
KHOLMADN_01563	3.86e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
KHOLMADN_01564	7.03e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
KHOLMADN_01565	8.93e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
KHOLMADN_01567	2.53e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
KHOLMADN_01568	2.78e-190	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
KHOLMADN_01569	9.98e-252	XK27_08315	-	-	M	-	-	-	Sulfatase
KHOLMADN_01570	2.07e-196	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
KHOLMADN_01571	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KHOLMADN_01572	8.91e-166	-	-	-	-	-	-	-	-
KHOLMADN_01573	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHOLMADN_01574	3.13e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
KHOLMADN_01575	6.61e-186	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KHOLMADN_01576	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
KHOLMADN_01577	0.0	potE	-	-	E	-	-	-	Amino Acid
KHOLMADN_01578	1.58e-239	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KHOLMADN_01579	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
KHOLMADN_01580	1.25e-208	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
KHOLMADN_01581	8.41e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
KHOLMADN_01582	1.72e-40	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
KHOLMADN_01583	7.5e-159	-	-	-	S	-	-	-	Putative threonine/serine exporter
KHOLMADN_01584	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
KHOLMADN_01585	2.47e-146	-	-	-	I	-	-	-	phosphatase
KHOLMADN_01586	3.45e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KHOLMADN_01588	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
KHOLMADN_01589	6.66e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
KHOLMADN_01595	1.06e-12	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHOLMADN_01596	1.51e-92	-	-	-	IQ	-	-	-	reductase
KHOLMADN_01597	7.14e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KHOLMADN_01598	1.12e-67	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
KHOLMADN_01599	6.64e-81	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
KHOLMADN_01600	6.92e-97	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
KHOLMADN_01601	3.27e-168	XK27_07210	-	-	S	-	-	-	B3 4 domain
KHOLMADN_01602	8.7e-71	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
KHOLMADN_01604	3.55e-62	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
KHOLMADN_01605	2.42e-06	-	-	-	K	-	-	-	LysR substrate binding domain
KHOLMADN_01606	3.86e-71	-	-	-	C	-	-	-	Aldo keto reductase
KHOLMADN_01607	4.15e-05	-	-	-	S	-	-	-	CsbD-like
KHOLMADN_01609	2.12e-36	-	-	-	C	-	-	-	Aldo/keto reductase family
KHOLMADN_01610	2.02e-116	-	-	-	P	-	-	-	Cadmium resistance transporter
KHOLMADN_01611	8.37e-42	ydzE	-	-	EG	-	-	-	spore germination
KHOLMADN_01612	8.58e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHOLMADN_01613	2.62e-300	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
KHOLMADN_01616	1.13e-09	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHOLMADN_01618	1.25e-11	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KHOLMADN_01619	4.15e-65	-	-	-	-	-	-	-	-
KHOLMADN_01620	1.64e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KHOLMADN_01621	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHOLMADN_01622	5.85e-169	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KHOLMADN_01623	1.03e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHOLMADN_01624	7.37e-16	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
KHOLMADN_01625	8.02e-62	-	-	-	-	-	-	-	-
KHOLMADN_01626	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KHOLMADN_01627	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
KHOLMADN_01628	4.49e-196	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KHOLMADN_01629	2.73e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHOLMADN_01630	1.67e-138	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KHOLMADN_01631	4.28e-273	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
KHOLMADN_01632	1.88e-310	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHOLMADN_01633	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHOLMADN_01634	7.4e-181	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KHOLMADN_01635	4.28e-182	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KHOLMADN_01636	4.15e-145	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KHOLMADN_01637	5.37e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KHOLMADN_01638	3.43e-88	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
KHOLMADN_01639	6.37e-48	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KHOLMADN_01641	1.85e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHOLMADN_01642	4.89e-201	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KHOLMADN_01643	2.93e-135	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHOLMADN_01644	2.2e-151	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KHOLMADN_01645	4.46e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
KHOLMADN_01646	8.03e-61	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
KHOLMADN_01647	7.18e-151	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
KHOLMADN_01648	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KHOLMADN_01649	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
KHOLMADN_01650	1.74e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KHOLMADN_01651	5.81e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHOLMADN_01652	2.15e-86	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
KHOLMADN_01653	1.08e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
KHOLMADN_01654	1.85e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
KHOLMADN_01655	1.75e-58	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KHOLMADN_01656	6.11e-88	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KHOLMADN_01657	4.39e-148	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KHOLMADN_01658	1.16e-60	ywjB	-	-	H	-	-	-	RibD C-terminal domain
KHOLMADN_01659	7.36e-204	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KHOLMADN_01660	8.37e-27	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHOLMADN_01662	1.25e-140	-	-	-	-	-	-	-	-
KHOLMADN_01663	1.84e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
KHOLMADN_01664	3.32e-209	-	-	-	K	-	-	-	LysR substrate binding domain
KHOLMADN_01665	3.84e-76	-	-	-	GM	-	-	-	NmrA-like family
KHOLMADN_01666	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
KHOLMADN_01667	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KHOLMADN_01668	9.61e-249	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
KHOLMADN_01669	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KHOLMADN_01670	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHOLMADN_01671	4.18e-34	nlhH_1	-	-	I	ko:K01066	-	ko00000,ko01000	acetylesterase activity
KHOLMADN_01672	0.0	-	-	-	E	-	-	-	amino acid
KHOLMADN_01673	5.23e-69	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
KHOLMADN_01674	1.38e-128	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
KHOLMADN_01675	1.75e-134	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHOLMADN_01676	7.78e-126	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KHOLMADN_01677	4.59e-100	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
KHOLMADN_01678	2.77e-21	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
KHOLMADN_01679	1.42e-234	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
KHOLMADN_01680	2.41e-76	-	-	-	-	-	-	-	-
KHOLMADN_01681	7.08e-205	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
KHOLMADN_01682	1.25e-32	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
KHOLMADN_01683	1.07e-300	-	-	-	F	ko:K03458	-	ko00000	Permease
KHOLMADN_01684	9.88e-205	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
KHOLMADN_01685	1.22e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHOLMADN_01686	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
KHOLMADN_01687	1.02e-141	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLMADN_01688	9.64e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
KHOLMADN_01689	6.2e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHOLMADN_01690	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KHOLMADN_01691	1.4e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KHOLMADN_01692	3.65e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHOLMADN_01693	6.61e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KHOLMADN_01694	2.04e-141	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
KHOLMADN_01697	2.92e-257	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
KHOLMADN_01698	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
KHOLMADN_01699	3.35e-79	-	-	-	L	-	-	-	Resolvase, N terminal domain
KHOLMADN_01701	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
KHOLMADN_01702	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
KHOLMADN_01703	4.7e-100	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
KHOLMADN_01704	9.9e-69	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
KHOLMADN_01705	1.99e-76	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
KHOLMADN_01706	3.31e-39	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
KHOLMADN_01707	4.13e-22	-	-	-	G	-	-	-	Major Facilitator
KHOLMADN_01708	3.39e-194	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
KHOLMADN_01709	0.0	yclK	-	-	T	-	-	-	Histidine kinase
KHOLMADN_01710	8.03e-170	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
KHOLMADN_01711	1.47e-195	-	-	-	D	-	-	-	nuclear chromosome segregation
KHOLMADN_01712	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
KHOLMADN_01713	1.53e-208	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KHOLMADN_01716	3.84e-148	-	-	-	-	-	-	-	-
KHOLMADN_01717	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
KHOLMADN_01722	2.3e-49	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
KHOLMADN_01723	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
KHOLMADN_01724	5.2e-143	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KHOLMADN_01725	1.82e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KHOLMADN_01726	1.53e-287	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KHOLMADN_01727	6.44e-139	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
KHOLMADN_01728	2.89e-251	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHOLMADN_01729	2.91e-63	-	-	-	C	-	-	-	FMN binding
KHOLMADN_01732	8.72e-279	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KHOLMADN_01733	1.2e-82	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
KHOLMADN_01734	8.66e-313	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHOLMADN_01735	1.54e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHOLMADN_01736	7.53e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
KHOLMADN_01737	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHOLMADN_01738	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
KHOLMADN_01739	2.46e-102	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
KHOLMADN_01740	1.53e-19	-	-	-	-	-	-	-	-
KHOLMADN_01741	1.29e-299	-	-	-	L	ko:K07485	-	ko00000	Transposase
KHOLMADN_01745	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHOLMADN_01746	3.28e-21	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KHOLMADN_01747	6.95e-53	-	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHOLMADN_01748	4.46e-211	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KHOLMADN_01758	2.96e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
KHOLMADN_01759	2.49e-31	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLMADN_01760	2.79e-139	-	-	-	L	-	-	-	Bacterial dnaA protein
KHOLMADN_01761	1.67e-204	-	-	-	L	-	-	-	Integrase core domain
KHOLMADN_01762	8.43e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
KHOLMADN_01763	2.29e-68	-	-	-	S	-	-	-	Cupredoxin-like domain
KHOLMADN_01764	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KHOLMADN_01765	7.26e-35	-	-	-	EGP	-	-	-	Major Facilitator
KHOLMADN_01766	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
KHOLMADN_01767	4.88e-151	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KHOLMADN_01768	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KHOLMADN_01769	1.09e-194	XK27_09800	-	-	I	-	-	-	Acyltransferase family
KHOLMADN_01770	2.2e-80	-	-	-	M	-	-	-	Glycosyl transferases group 1
KHOLMADN_01771	2.78e-223	epsH	-	-	M	-	-	-	Glycosyl transferase family 2
KHOLMADN_01772	4.26e-225	-	-	-	S	-	-	-	Protein conserved in bacteria
KHOLMADN_01773	2.23e-221	-	-	-	S	-	-	-	EpsG family
KHOLMADN_01774	4.44e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
KHOLMADN_01775	5.03e-181	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
KHOLMADN_01776	8.75e-134	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHOLMADN_01777	1.08e-51	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHOLMADN_01778	1.28e-87	-	-	-	S	-	-	-	Flavodoxin
KHOLMADN_01779	4.8e-119	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
KHOLMADN_01782	1.63e-82	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
KHOLMADN_01783	7.62e-142	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KHOLMADN_01784	4.29e-35	yitW	-	-	S	-	-	-	DNA methyltransferase
KHOLMADN_01785	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHOLMADN_01786	5.74e-285	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KHOLMADN_01787	6.78e-225	-	-	-	-	-	-	-	-
KHOLMADN_01788	2.32e-233	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
KHOLMADN_01789	8.13e-206	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
KHOLMADN_01790	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHOLMADN_01791	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHOLMADN_01792	3.38e-146	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
KHOLMADN_01793	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
KHOLMADN_01794	1.38e-61	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KHOLMADN_01795	8.34e-101	-	-	-	-	-	-	-	-
KHOLMADN_01796	9.03e-79	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
KHOLMADN_01797	1.05e-59	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
KHOLMADN_01798	1.97e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KHOLMADN_01799	4.65e-58	yodA	-	-	S	-	-	-	Tautomerase enzyme
KHOLMADN_01800	3.79e-07	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
KHOLMADN_01802	2.69e-148	pnb	-	-	C	-	-	-	nitroreductase
KHOLMADN_01804	5.28e-13	-	-	-	-	-	-	-	-
KHOLMADN_01807	2.39e-106	-	-	-	S	-	-	-	Carboxymuconolactone decarboxylase family
KHOLMADN_01808	4.78e-296	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
KHOLMADN_01809	1.02e-256	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
KHOLMADN_01810	1.85e-120	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
KHOLMADN_01811	1.53e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHOLMADN_01812	7.44e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KHOLMADN_01813	7.99e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
KHOLMADN_01814	2.01e-87	-	-	-	M	-	-	-	LysM domain protein
KHOLMADN_01815	2e-109	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
KHOLMADN_01816	7.69e-100	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KHOLMADN_01817	7.07e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
KHOLMADN_01818	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHOLMADN_01819	2.33e-51	-	-	-	S	-	-	-	Cytochrome B5
KHOLMADN_01820	1.31e-121	-	-	-	-	-	-	-	-
KHOLMADN_01821	3.04e-32	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
KHOLMADN_01822	8.47e-106	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KHOLMADN_01823	1.39e-40	-	-	-	S	-	-	-	Transglycosylase associated protein
KHOLMADN_01824	4.74e-23	-	-	-	-	-	-	-	-
KHOLMADN_01826	2.91e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
KHOLMADN_01828	9.78e-73	-	-	-	K	-	-	-	Transcriptional regulator
KHOLMADN_01829	2.64e-51	-	-	-	-	-	-	-	-
KHOLMADN_01830	3.07e-12	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KHOLMADN_01831	2.21e-229	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHOLMADN_01834	4.58e-246	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KHOLMADN_01835	2.35e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
KHOLMADN_01836	6.08e-42	-	-	-	S	-	-	-	Cytochrome B5
KHOLMADN_01837	9.82e-18	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
KHOLMADN_01838	1.07e-23	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
KHOLMADN_01849	1.02e-19	-	-	-	-	-	-	-	-
KHOLMADN_01850	7.87e-88	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
KHOLMADN_01854	1.58e-57	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
KHOLMADN_01855	6.35e-99	-	-	-	O	-	-	-	Bacterial dnaA protein
KHOLMADN_01856	5.36e-61	-	-	-	M	-	-	-	Acetyltransferase (Isoleucine patch superfamily)
KHOLMADN_01858	7.85e-139	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHOLMADN_01859	2.51e-40	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
KHOLMADN_01860	2.84e-97	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
KHOLMADN_01868	2.95e-22	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core