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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HHOLBAFO_00001	1.73e-235	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHOLBAFO_00002	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HHOLBAFO_00003	2e-142	-	-	-	-	-	-	-	-
HHOLBAFO_00004	3.04e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HHOLBAFO_00005	2.89e-152	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HHOLBAFO_00006	2.44e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHOLBAFO_00007	4.35e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HHOLBAFO_00008	1.87e-132	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HHOLBAFO_00009	1.2e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HHOLBAFO_00010	7.57e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HHOLBAFO_00011	5.77e-255	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HHOLBAFO_00013	1.27e-48	-	-	-	-	-	-	-	-
HHOLBAFO_00015	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HHOLBAFO_00016	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HHOLBAFO_00017	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HHOLBAFO_00018	5.02e-228	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOLBAFO_00019	3.85e-191	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHOLBAFO_00021	2.49e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HHOLBAFO_00022	4.3e-170	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00023	1.22e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HHOLBAFO_00024	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHOLBAFO_00025	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
HHOLBAFO_00026	8.85e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
HHOLBAFO_00027	1.3e-151	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHOLBAFO_00028	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HHOLBAFO_00029	7.17e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HHOLBAFO_00030	1.14e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HHOLBAFO_00031	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHOLBAFO_00032	3.08e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHOLBAFO_00033	2.4e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHOLBAFO_00034	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHOLBAFO_00035	1.9e-312	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HHOLBAFO_00036	3.11e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HHOLBAFO_00037	4.02e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHOLBAFO_00038	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HHOLBAFO_00039	2.71e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHOLBAFO_00040	2.58e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HHOLBAFO_00041	1.55e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HHOLBAFO_00042	7.72e-122	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HHOLBAFO_00043	2.67e-274	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HHOLBAFO_00044	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HHOLBAFO_00045	3.65e-117	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHOLBAFO_00046	4.54e-144	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HHOLBAFO_00047	1.09e-74	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHOLBAFO_00048	4.1e-172	yqeM	-	-	Q	-	-	-	Methyltransferase
HHOLBAFO_00049	3.78e-270	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HHOLBAFO_00050	9.71e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HHOLBAFO_00051	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HHOLBAFO_00052	5.62e-155	csrR	-	-	K	-	-	-	response regulator
HHOLBAFO_00053	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLBAFO_00054	2.56e-296	-	-	-	V	-	-	-	MatE
HHOLBAFO_00055	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HHOLBAFO_00056	1.03e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHOLBAFO_00057	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HHOLBAFO_00058	6.89e-176	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHOLBAFO_00059	9.61e-116	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOLBAFO_00060	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HHOLBAFO_00061	2.58e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHOLBAFO_00062	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHOLBAFO_00063	5.91e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HHOLBAFO_00064	7.39e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHOLBAFO_00065	0.0	-	-	-	S	-	-	-	membrane
HHOLBAFO_00066	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HHOLBAFO_00067	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HHOLBAFO_00068	5.19e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHOLBAFO_00069	7.33e-136	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HHOLBAFO_00070	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HHOLBAFO_00071	8.69e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HHOLBAFO_00072	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HHOLBAFO_00073	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HHOLBAFO_00074	1.48e-219	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHOLBAFO_00075	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HHOLBAFO_00076	4.76e-19	-	-	-	-	-	-	-	-
HHOLBAFO_00077	1.34e-201	-	-	-	-	-	-	-	-
HHOLBAFO_00078	3.88e-225	-	-	-	-	-	-	-	-
HHOLBAFO_00079	2.22e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
HHOLBAFO_00080	1.51e-258	-	-	-	S	-	-	-	Phage integrase family
HHOLBAFO_00081	1.17e-95	-	-	-	-	-	-	-	-
HHOLBAFO_00082	8.82e-23	-	-	-	S	-	-	-	zinc-ribbon domain
HHOLBAFO_00083	1.1e-22	-	-	-	K	-	-	-	Helix-turn-helix
HHOLBAFO_00085	1.73e-104	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HHOLBAFO_00092	3.96e-180	-	-	-	S	-	-	-	DNA metabolic process
HHOLBAFO_00093	3.34e-208	-	-	-	S	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HHOLBAFO_00094	1.68e-86	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHOLBAFO_00095	1.47e-32	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HHOLBAFO_00099	1.28e-127	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
HHOLBAFO_00102	4.36e-198	-	-	-	S	-	-	-	HNH endonuclease
HHOLBAFO_00103	4.19e-101	-	-	-	S	-	-	-	Phage terminase, small subunit
HHOLBAFO_00104	0.0	-	-	-	S	-	-	-	Phage Terminase
HHOLBAFO_00106	4.32e-297	-	-	-	S	-	-	-	Phage portal protein
HHOLBAFO_00107	4.85e-87	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HHOLBAFO_00108	1.09e-254	-	-	-	S	-	-	-	peptidase activity
HHOLBAFO_00109	4.29e-64	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HHOLBAFO_00110	1.52e-29	-	-	-	S	-	-	-	Phage head-tail joining protein
HHOLBAFO_00111	1.01e-48	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HHOLBAFO_00112	4.68e-55	-	-	-	-	-	-	-	-
HHOLBAFO_00113	6.14e-135	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
HHOLBAFO_00115	2.14e-19	-	-	-	-	-	-	-	-
HHOLBAFO_00116	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HHOLBAFO_00117	2.55e-199	-	-	-	S	-	-	-	Phage tail protein
HHOLBAFO_00118	3.38e-134	-	-	-	M	-	-	-	Prophage endopeptidase tail
HHOLBAFO_00119	1.59e-12	spoIVFA	-	GT2,GT4	D	ko:K05802,ko:K06401,ko:K20444,ko:K22051	-	ko00000,ko01000,ko01005,ko02000	peptidase
HHOLBAFO_00123	9.61e-64	-	-	-	-	-	-	-	-
HHOLBAFO_00127	1.77e-117	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HHOLBAFO_00128	2.91e-18	-	-	-	-	-	-	-	-
HHOLBAFO_00129	2.46e-102	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HHOLBAFO_00130	1.85e-84	-	-	-	L	-	-	-	Transposase
HHOLBAFO_00131	1.44e-41	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HHOLBAFO_00133	8.72e-147	-	-	-	K	-	-	-	Transcriptional regulator
HHOLBAFO_00134	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HHOLBAFO_00135	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HHOLBAFO_00136	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HHOLBAFO_00137	6.91e-25	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HHOLBAFO_00138	2.42e-262	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HHOLBAFO_00139	4.24e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HHOLBAFO_00140	8.07e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHOLBAFO_00141	9.52e-205	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHOLBAFO_00142	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHOLBAFO_00143	3.3e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHOLBAFO_00144	3.42e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HHOLBAFO_00145	3.27e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HHOLBAFO_00146	4.92e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HHOLBAFO_00147	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HHOLBAFO_00149	4.19e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HHOLBAFO_00150	3.16e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHOLBAFO_00151	1.7e-281	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHOLBAFO_00152	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHOLBAFO_00153	7.64e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHOLBAFO_00154	1.06e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHOLBAFO_00155	7.64e-166	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HHOLBAFO_00156	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HHOLBAFO_00157	1.53e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHOLBAFO_00158	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HHOLBAFO_00159	9.12e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HHOLBAFO_00160	1e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HHOLBAFO_00161	1.18e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HHOLBAFO_00162	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HHOLBAFO_00163	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHOLBAFO_00164	1.27e-214	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHOLBAFO_00165	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHOLBAFO_00166	1.62e-165	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHOLBAFO_00167	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HHOLBAFO_00168	6.36e-257	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHOLBAFO_00169	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHOLBAFO_00170	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHOLBAFO_00171	1.15e-67	-	-	-	-	-	-	-	-
HHOLBAFO_00172	6.01e-34	-	-	-	-	-	-	-	-
HHOLBAFO_00173	8.38e-169	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HHOLBAFO_00174	9.44e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HHOLBAFO_00175	4.79e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HHOLBAFO_00176	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HHOLBAFO_00177	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHOLBAFO_00178	2.78e-158	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HHOLBAFO_00179	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HHOLBAFO_00180	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HHOLBAFO_00181	1.78e-113	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHOLBAFO_00182	2.22e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HHOLBAFO_00183	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HHOLBAFO_00184	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHOLBAFO_00185	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
HHOLBAFO_00186	8.43e-190	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
HHOLBAFO_00187	1.12e-51	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
HHOLBAFO_00188	6.34e-163	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
HHOLBAFO_00189	2.01e-82	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HHOLBAFO_00190	2.75e-89	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
HHOLBAFO_00191	7.6e-161	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHOLBAFO_00192	1.19e-99	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
HHOLBAFO_00193	1.11e-41	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HHOLBAFO_00195	1.74e-111	-	-	-	K	-	-	-	GNAT family
HHOLBAFO_00196	7.37e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HHOLBAFO_00197	7.54e-205	yvgN	-	-	S	-	-	-	Aldo keto reductase
HHOLBAFO_00198	4.49e-185	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHOLBAFO_00199	1.44e-165	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HHOLBAFO_00201	1.55e-74	-	-	-	-	-	-	-	-
HHOLBAFO_00203	3.24e-10	-	-	-	-	-	-	-	-
HHOLBAFO_00204	3.43e-101	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
HHOLBAFO_00205	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00206	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHOLBAFO_00207	1.79e-243	ampC	-	-	V	-	-	-	Beta-lactamase
HHOLBAFO_00208	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHOLBAFO_00209	2.31e-63	-	-	-	-	-	-	-	-
HHOLBAFO_00210	7.49e-181	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HHOLBAFO_00211	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HHOLBAFO_00212	5.15e-142	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HHOLBAFO_00213	1.26e-206	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHOLBAFO_00214	1.07e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHOLBAFO_00215	3.1e-246	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHOLBAFO_00216	2.12e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHOLBAFO_00217	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHOLBAFO_00218	4.71e-251	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HHOLBAFO_00219	7.81e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HHOLBAFO_00220	5.22e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HHOLBAFO_00221	3.82e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HHOLBAFO_00222	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHOLBAFO_00223	1.31e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHOLBAFO_00224	1.23e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHOLBAFO_00225	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHOLBAFO_00226	7.25e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHOLBAFO_00227	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHOLBAFO_00228	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HHOLBAFO_00229	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HHOLBAFO_00230	7.68e-275	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HHOLBAFO_00231	2.7e-233	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HHOLBAFO_00232	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HHOLBAFO_00233	2.82e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HHOLBAFO_00235	4.67e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HHOLBAFO_00236	4.61e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HHOLBAFO_00237	5.45e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLBAFO_00238	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
HHOLBAFO_00240	2.62e-300	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HHOLBAFO_00241	1.9e-109	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HHOLBAFO_00242	5.1e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HHOLBAFO_00243	2.3e-173	-	-	-	S	-	-	-	Membrane
HHOLBAFO_00244	1.74e-189	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHOLBAFO_00245	2.8e-20	-	-	-	S	-	-	-	YjcQ protein
HHOLBAFO_00248	3.25e-223	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOLBAFO_00249	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHOLBAFO_00250	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHOLBAFO_00251	2.77e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HHOLBAFO_00252	1.67e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHOLBAFO_00253	4.6e-277	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HHOLBAFO_00254	1.91e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HHOLBAFO_00255	7.42e-14	-	-	-	M	-	-	-	LysM domain
HHOLBAFO_00256	1.52e-50	-	-	-	-	-	-	-	-
HHOLBAFO_00257	1.79e-18	-	-	-	S	-	-	-	zinc-ribbon domain
HHOLBAFO_00259	2.56e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHOLBAFO_00260	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHOLBAFO_00261	1.89e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HHOLBAFO_00262	5.3e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HHOLBAFO_00263	1.56e-231	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HHOLBAFO_00264	1.12e-186	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HHOLBAFO_00265	9.04e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HHOLBAFO_00266	1.09e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HHOLBAFO_00267	2.81e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00268	1.84e-202	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLBAFO_00269	2.71e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HHOLBAFO_00270	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HHOLBAFO_00271	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
HHOLBAFO_00272	1.79e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHOLBAFO_00273	1.88e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HHOLBAFO_00274	7.88e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHOLBAFO_00275	2.08e-280	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HHOLBAFO_00276	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHOLBAFO_00277	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHOLBAFO_00278	3.58e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHOLBAFO_00279	3.61e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHOLBAFO_00280	3.75e-219	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
HHOLBAFO_00281	9.66e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HHOLBAFO_00282	7.69e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HHOLBAFO_00283	6.93e-300	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHOLBAFO_00284	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHOLBAFO_00285	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HHOLBAFO_00286	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHOLBAFO_00287	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HHOLBAFO_00288	2.16e-209	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHOLBAFO_00289	9.07e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
HHOLBAFO_00290	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHOLBAFO_00291	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HHOLBAFO_00292	9.85e-282	-	-	-	P	-	-	-	Chloride transporter, ClC family
HHOLBAFO_00293	7.99e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HHOLBAFO_00294	7.44e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HHOLBAFO_00295	7.28e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHOLBAFO_00296	2.25e-121	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HHOLBAFO_00297	1.75e-193	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HHOLBAFO_00298	8.71e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HHOLBAFO_00299	5.99e-67	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHOLBAFO_00300	4.62e-92	-	-	-	-	-	-	-	-
HHOLBAFO_00301	4.41e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HHOLBAFO_00302	1.4e-236	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HHOLBAFO_00303	4.68e-180	-	-	-	-	-	-	-	-
HHOLBAFO_00304	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HHOLBAFO_00305	2.23e-121	-	-	-	M	-	-	-	PFAM NLP P60 protein
HHOLBAFO_00306	1.71e-181	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HHOLBAFO_00307	4.08e-249	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HHOLBAFO_00308	1.82e-226	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HHOLBAFO_00309	1.01e-210	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HHOLBAFO_00310	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HHOLBAFO_00315	2.06e-201	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HHOLBAFO_00316	6.46e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHOLBAFO_00317	2.24e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HHOLBAFO_00318	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HHOLBAFO_00319	1.18e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHOLBAFO_00320	9.59e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HHOLBAFO_00321	5.37e-138	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HHOLBAFO_00322	6.93e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HHOLBAFO_00323	3.4e-116	-	-	-	GM	-	-	-	epimerase
HHOLBAFO_00324	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HHOLBAFO_00325	7.2e-108	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HHOLBAFO_00326	1.49e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HHOLBAFO_00327	2.08e-265	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HHOLBAFO_00328	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHOLBAFO_00329	8.49e-121	-	-	-	S	-	-	-	module of peptide synthetase
HHOLBAFO_00330	2.07e-190	-	-	-	C	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_00331	2.67e-286	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
HHOLBAFO_00332	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HHOLBAFO_00333	5.7e-144	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HHOLBAFO_00334	6.46e-289	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
HHOLBAFO_00335	1.23e-308	uidA	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HHOLBAFO_00336	1.43e-241	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HHOLBAFO_00337	3.29e-153	-	-	-	G	-	-	-	Glycosyl hydrolases family 28
HHOLBAFO_00338	7.22e-154	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
HHOLBAFO_00339	5.94e-274	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HHOLBAFO_00340	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HHOLBAFO_00341	2.54e-275	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HHOLBAFO_00342	1.47e-195	-	-	-	V	-	-	-	MatE
HHOLBAFO_00343	1.68e-109	-	-	-	K	-	-	-	FCD domain
HHOLBAFO_00344	8.82e-49	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HHOLBAFO_00345	1.47e-304	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HHOLBAFO_00346	9.27e-309	-	5.1.2.7	-	S	ko:K21619	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	tagaturonate epimerase
HHOLBAFO_00347	6.26e-290	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HHOLBAFO_00350	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHOLBAFO_00351	2.13e-106	usp5	-	-	T	-	-	-	universal stress protein
HHOLBAFO_00352	3.07e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HHOLBAFO_00353	6.61e-181	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLBAFO_00354	2.02e-126	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_00355	5.62e-228	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHOLBAFO_00356	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HHOLBAFO_00357	5.27e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHOLBAFO_00358	6.15e-161	-	-	-	S	-	-	-	Membrane
HHOLBAFO_00359	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HHOLBAFO_00360	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HHOLBAFO_00361	2.49e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HHOLBAFO_00362	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HHOLBAFO_00363	7.25e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHOLBAFO_00364	1.9e-231	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HHOLBAFO_00365	6.55e-183	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HHOLBAFO_00366	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HHOLBAFO_00367	1.21e-48	-	-	-	-	-	-	-	-
HHOLBAFO_00368	6.87e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00369	4.27e-155	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLBAFO_00370	3.12e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HHOLBAFO_00371	9.08e-71	-	-	-	-	-	-	-	-
HHOLBAFO_00372	2.73e-213	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_00373	4.97e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHOLBAFO_00374	4.17e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HHOLBAFO_00375	1.16e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HHOLBAFO_00376	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HHOLBAFO_00377	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HHOLBAFO_00378	5.76e-59	-	-	-	-	-	-	-	-
HHOLBAFO_00379	9.34e-266	-	-	-	S	-	-	-	Putative metallopeptidase domain
HHOLBAFO_00380	4.5e-260	-	-	-	S	-	-	-	associated with various cellular activities
HHOLBAFO_00381	8.13e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HHOLBAFO_00382	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HHOLBAFO_00384	7.76e-160	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HHOLBAFO_00385	3.05e-73	-	-	-	-	-	-	-	-
HHOLBAFO_00386	3.55e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HHOLBAFO_00387	9.3e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHOLBAFO_00388	3.97e-137	-	-	-	-	-	-	-	-
HHOLBAFO_00389	9.16e-35	-	-	-	-	-	-	-	-
HHOLBAFO_00390	6.76e-215	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HHOLBAFO_00391	3.91e-281	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHOLBAFO_00392	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HHOLBAFO_00393	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HHOLBAFO_00394	4.81e-157	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00395	6.69e-208	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HHOLBAFO_00396	4.36e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLBAFO_00397	6.45e-240	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HHOLBAFO_00398	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HHOLBAFO_00399	2.25e-57	-	-	-	-	-	-	-	-
HHOLBAFO_00400	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHOLBAFO_00401	3.92e-109	-	-	-	L	-	-	-	nuclease
HHOLBAFO_00402	1.46e-207	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HHOLBAFO_00403	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HHOLBAFO_00404	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHOLBAFO_00405	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHOLBAFO_00406	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HHOLBAFO_00407	7.54e-285	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HHOLBAFO_00408	5.94e-75	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHOLBAFO_00409	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHOLBAFO_00410	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHOLBAFO_00411	1.31e-190	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HHOLBAFO_00412	5.82e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHOLBAFO_00413	5.32e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHOLBAFO_00414	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HHOLBAFO_00416	3.8e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHOLBAFO_00417	1.52e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHOLBAFO_00418	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HHOLBAFO_00419	9.75e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHOLBAFO_00420	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHOLBAFO_00421	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHOLBAFO_00422	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HHOLBAFO_00423	1.7e-151	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHOLBAFO_00424	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHOLBAFO_00425	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HHOLBAFO_00426	2.16e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HHOLBAFO_00427	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HHOLBAFO_00428	1.47e-266	-	-	-	E	-	-	-	Major Facilitator Superfamily
HHOLBAFO_00429	6.3e-81	-	-	-	-	-	-	-	-
HHOLBAFO_00430	2.85e-77	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHOLBAFO_00431	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HHOLBAFO_00432	1.05e-202	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HHOLBAFO_00433	2e-08	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HHOLBAFO_00434	6.99e-32	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HHOLBAFO_00435	6.74e-143	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HHOLBAFO_00436	3.79e-54	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HHOLBAFO_00437	1.54e-138	-	-	-	L	-	-	-	Integrase
HHOLBAFO_00438	4.58e-59	-	-	-	K	-	-	-	transcriptional regulator
HHOLBAFO_00439	1e-09	-	-	-	GM	-	-	-	NmrA-like family
HHOLBAFO_00440	4.06e-29	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HHOLBAFO_00442	1.19e-97	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HHOLBAFO_00443	8.69e-96	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
HHOLBAFO_00444	9.54e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
HHOLBAFO_00445	1.11e-206	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HHOLBAFO_00446	6.02e-137	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HHOLBAFO_00447	9.01e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00448	4.6e-131	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HHOLBAFO_00449	9.99e-183	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HHOLBAFO_00450	5.58e-248	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HHOLBAFO_00451	1.76e-279	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HHOLBAFO_00452	1.33e-227	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHOLBAFO_00453	2.93e-259	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HHOLBAFO_00454	1.83e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HHOLBAFO_00455	1.52e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HHOLBAFO_00456	1.14e-213	yvgN	-	-	C	-	-	-	Aldo keto reductase
HHOLBAFO_00457	1.14e-203	-	-	-	S	-	-	-	DUF218 domain
HHOLBAFO_00458	1.06e-35	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HHOLBAFO_00459	3.71e-122	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HHOLBAFO_00460	1.49e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HHOLBAFO_00461	5e-112	-	-	-	S	-	-	-	Phage minor capsid protein 2
HHOLBAFO_00462	6.24e-41	-	-	-	S	-	-	-	Phage minor capsid protein 2
HHOLBAFO_00465	1.81e-274	-	-	-	E	-	-	-	Aminotransferase
HHOLBAFO_00466	8.72e-89	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HHOLBAFO_00467	1.23e-66	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HHOLBAFO_00468	2.23e-280	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HHOLBAFO_00469	1.59e-117	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HHOLBAFO_00470	1.74e-41	-	-	-	S	-	-	-	Fic/DOC family
HHOLBAFO_00471	2.97e-108	-	-	-	S	-	-	-	Fic/DOC family
HHOLBAFO_00472	5.52e-105	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HHOLBAFO_00473	1.27e-123	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HHOLBAFO_00474	1.1e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HHOLBAFO_00475	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
HHOLBAFO_00476	7.15e-154	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
HHOLBAFO_00477	2.15e-114	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HHOLBAFO_00478	2.4e-61	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HHOLBAFO_00479	3.21e-10	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HHOLBAFO_00480	3.57e-56	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HHOLBAFO_00481	5.63e-60	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HHOLBAFO_00482	4.89e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HHOLBAFO_00484	1.87e-306	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HHOLBAFO_00485	6.56e-134	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HHOLBAFO_00486	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HHOLBAFO_00488	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HHOLBAFO_00489	4.38e-306	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HHOLBAFO_00490	6.88e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HHOLBAFO_00491	1.84e-104	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HHOLBAFO_00492	1.21e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HHOLBAFO_00493	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HHOLBAFO_00494	2.26e-91	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HHOLBAFO_00495	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HHOLBAFO_00496	1.71e-121	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HHOLBAFO_00497	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHOLBAFO_00498	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHOLBAFO_00499	7.47e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHOLBAFO_00500	8.93e-218	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HHOLBAFO_00501	6.14e-196	-	-	-	D	-	-	-	DNA integration
HHOLBAFO_00502	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHOLBAFO_00503	4.22e-211	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HHOLBAFO_00504	1.18e-179	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHOLBAFO_00505	6.95e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHOLBAFO_00506	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HHOLBAFO_00507	1.65e-134	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HHOLBAFO_00508	1.66e-215	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HHOLBAFO_00509	1.99e-145	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HHOLBAFO_00510	1.97e-276	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HHOLBAFO_00511	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HHOLBAFO_00512	1.34e-139	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HHOLBAFO_00513	1.12e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHOLBAFO_00514	7.26e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHOLBAFO_00515	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00516	4.18e-282	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHOLBAFO_00517	1.81e-202	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HHOLBAFO_00518	2.41e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HHOLBAFO_00519	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHOLBAFO_00520	1.29e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HHOLBAFO_00521	1.33e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HHOLBAFO_00522	3.8e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HHOLBAFO_00523	2.27e-67	-	-	-	M	-	-	-	Lysin motif
HHOLBAFO_00524	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HHOLBAFO_00525	1.34e-254	-	-	-	S	-	-	-	Helix-turn-helix domain
HHOLBAFO_00526	2.89e-112	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHOLBAFO_00527	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HHOLBAFO_00528	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHOLBAFO_00529	2.79e-181	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHOLBAFO_00530	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHOLBAFO_00531	7.32e-176	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HHOLBAFO_00532	2.55e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HHOLBAFO_00533	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HHOLBAFO_00534	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HHOLBAFO_00536	5.68e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HHOLBAFO_00537	1.16e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHOLBAFO_00538	2.3e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HHOLBAFO_00539	8.69e-23	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HHOLBAFO_00540	2.01e-108	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HHOLBAFO_00541	3.95e-230	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HHOLBAFO_00542	1.23e-251	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHOLBAFO_00543	8.98e-274	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HHOLBAFO_00544	1.01e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHOLBAFO_00545	2.87e-219	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHOLBAFO_00546	1.9e-279	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHOLBAFO_00547	2.59e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHOLBAFO_00548	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHOLBAFO_00549	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HHOLBAFO_00550	8.7e-233	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHOLBAFO_00551	4.07e-215	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHOLBAFO_00552	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HHOLBAFO_00553	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLBAFO_00554	2.34e-302	yycH	-	-	S	-	-	-	YycH protein
HHOLBAFO_00555	9.32e-182	yycI	-	-	S	-	-	-	YycH protein
HHOLBAFO_00556	1.57e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HHOLBAFO_00557	1.29e-267	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HHOLBAFO_00558	1.43e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHOLBAFO_00559	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
HHOLBAFO_00560	1.55e-223	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HHOLBAFO_00561	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HHOLBAFO_00562	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HHOLBAFO_00563	4.45e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HHOLBAFO_00564	4.7e-141	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
HHOLBAFO_00566	8.96e-11	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00567	1.02e-40	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00568	1.41e-242	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHOLBAFO_00569	7.45e-231	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HHOLBAFO_00570	8.98e-228	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_00571	3.5e-271	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HHOLBAFO_00572	7.83e-46	-	-	-	-	-	-	-	-
HHOLBAFO_00573	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HHOLBAFO_00574	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHOLBAFO_00575	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HHOLBAFO_00576	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HHOLBAFO_00577	1.04e-209	-	-	-	C	-	-	-	Aldo keto reductase
HHOLBAFO_00578	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HHOLBAFO_00579	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HHOLBAFO_00580	7.38e-226	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HHOLBAFO_00581	2.41e-116	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HHOLBAFO_00582	1.39e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHOLBAFO_00583	8.33e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHOLBAFO_00584	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HHOLBAFO_00585	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHOLBAFO_00586	5.85e-169	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHOLBAFO_00587	3.58e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHOLBAFO_00588	7.37e-16	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
HHOLBAFO_00589	8.02e-62	-	-	-	-	-	-	-	-
HHOLBAFO_00590	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HHOLBAFO_00591	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HHOLBAFO_00592	3.16e-196	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HHOLBAFO_00593	2.73e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHOLBAFO_00594	7.93e-137	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HHOLBAFO_00595	1.05e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HHOLBAFO_00596	6.55e-311	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHOLBAFO_00597	3.1e-247	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HHOLBAFO_00598	1.08e-154	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HHOLBAFO_00599	5.01e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHOLBAFO_00600	3.78e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHOLBAFO_00601	7.53e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HHOLBAFO_00602	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHOLBAFO_00603	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HHOLBAFO_00604	1.75e-276	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HHOLBAFO_00605	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HHOLBAFO_00606	3.66e-315	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHOLBAFO_00609	1.25e-140	-	-	-	-	-	-	-	-
HHOLBAFO_00610	4.52e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HHOLBAFO_00611	2.33e-209	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLBAFO_00612	6.68e-77	-	-	-	GM	-	-	-	NmrA-like family
HHOLBAFO_00613	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HHOLBAFO_00614	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HHOLBAFO_00615	1.12e-247	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HHOLBAFO_00616	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLBAFO_00617	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHOLBAFO_00618	2.71e-50	nlhH_1	-	-	I	ko:K01066	-	ko00000,ko01000	acetylesterase activity
HHOLBAFO_00620	3.92e-99	mleR	-	-	K	-	-	-	LysR family
HHOLBAFO_00621	3.78e-290	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HHOLBAFO_00622	2.47e-234	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HHOLBAFO_00623	3.53e-117	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HHOLBAFO_00624	9.29e-283	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHOLBAFO_00625	1.06e-268	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HHOLBAFO_00626	4.12e-287	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HHOLBAFO_00627	2.63e-208	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HHOLBAFO_00628	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HHOLBAFO_00629	6.93e-155	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HHOLBAFO_00630	2.62e-239	-	-	-	I	-	-	-	Alpha beta
HHOLBAFO_00631	1.66e-137	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HHOLBAFO_00632	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHOLBAFO_00634	2.99e-217	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HHOLBAFO_00635	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HHOLBAFO_00636	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HHOLBAFO_00637	2.07e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HHOLBAFO_00638	1.57e-314	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HHOLBAFO_00639	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HHOLBAFO_00640	1.3e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HHOLBAFO_00641	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HHOLBAFO_00642	7.71e-94	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HHOLBAFO_00643	1.15e-77	-	-	-	-	-	-	-	-
HHOLBAFO_00644	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHOLBAFO_00645	1.87e-283	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HHOLBAFO_00646	5.89e-29	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
HHOLBAFO_00647	1.44e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HHOLBAFO_00648	2.24e-140	-	-	-	S	-	-	-	VIT family
HHOLBAFO_00649	9.24e-151	-	-	-	S	-	-	-	membrane
HHOLBAFO_00650	1.25e-208	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HHOLBAFO_00651	8.41e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HHOLBAFO_00652	1.72e-40	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HHOLBAFO_00653	7.5e-159	-	-	-	S	-	-	-	Putative threonine/serine exporter
HHOLBAFO_00654	4.05e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HHOLBAFO_00655	2.47e-146	-	-	-	I	-	-	-	phosphatase
HHOLBAFO_00656	2.95e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HHOLBAFO_00658	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HHOLBAFO_00659	6.66e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HHOLBAFO_00665	5.13e-115	-	-	-	IQ	-	-	-	reductase
HHOLBAFO_00666	5.86e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHOLBAFO_00667	3.92e-68	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HHOLBAFO_00668	2.77e-92	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
HHOLBAFO_00669	2.01e-46	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HHOLBAFO_00670	3.01e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HHOLBAFO_00671	4.84e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
HHOLBAFO_00672	2.65e-245	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HHOLBAFO_00673	2e-239	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HHOLBAFO_00675	4.23e-283	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHOLBAFO_00676	1.1e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00677	1.55e-315	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HHOLBAFO_00678	7.34e-271	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HHOLBAFO_00679	5.42e-184	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HHOLBAFO_00680	6.1e-172	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HHOLBAFO_00681	3.3e-209	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HHOLBAFO_00682	7.2e-187	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HHOLBAFO_00683	1.47e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HHOLBAFO_00684	3.53e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHOLBAFO_00685	3.23e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HHOLBAFO_00686	6.97e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHOLBAFO_00687	4.9e-218	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HHOLBAFO_00688	6.47e-168	epsB	-	-	M	-	-	-	biosynthesis protein
HHOLBAFO_00689	1.01e-150	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HHOLBAFO_00690	8e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HHOLBAFO_00691	1.46e-114	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HHOLBAFO_00692	1.43e-88	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
HHOLBAFO_00693	2.08e-74	-	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HHOLBAFO_00694	8.05e-100	-	-	-	-	-	-	-	-
HHOLBAFO_00696	1.47e-36	epsJ2	-	-	S	-	-	-	Glycosyltransferase like family 2
HHOLBAFO_00697	1.21e-51	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HHOLBAFO_00698	1.41e-172	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HHOLBAFO_00699	4.85e-91	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
HHOLBAFO_00700	0.000304	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HHOLBAFO_00701	9.8e-126	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HHOLBAFO_00702	8.57e-132	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HHOLBAFO_00703	6.48e-120	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
HHOLBAFO_00704	7.15e-157	vanR	-	-	K	-	-	-	response regulator
HHOLBAFO_00705	2.09e-265	hpk31	-	-	T	-	-	-	Histidine kinase
HHOLBAFO_00706	2.32e-260	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHOLBAFO_00707	6.89e-177	-	-	-	E	-	-	-	AzlC protein
HHOLBAFO_00708	4.31e-76	-	-	-	S	-	-	-	branched-chain amino acid
HHOLBAFO_00709	1.89e-130	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HHOLBAFO_00710	3.91e-289	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HHOLBAFO_00711	3.23e-10	-	-	-	K	-	-	-	transcriptional regulator
HHOLBAFO_00712	1.64e-222	ydbI	-	-	K	-	-	-	AI-2E family transporter
HHOLBAFO_00713	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HHOLBAFO_00714	3.36e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHOLBAFO_00715	7.98e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHOLBAFO_00716	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHOLBAFO_00717	7.67e-219	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
HHOLBAFO_00718	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HHOLBAFO_00719	3.55e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HHOLBAFO_00720	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHOLBAFO_00721	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHOLBAFO_00722	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHOLBAFO_00723	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHOLBAFO_00724	1.13e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HHOLBAFO_00725	6.26e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHOLBAFO_00726	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HHOLBAFO_00727	2.39e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
HHOLBAFO_00728	2.41e-156	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HHOLBAFO_00730	6.87e-82	-	-	-	S	-	-	-	YjbR
HHOLBAFO_00731	3.97e-113	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HHOLBAFO_00732	2.59e-17	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HHOLBAFO_00733	1.97e-111	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HHOLBAFO_00734	1.94e-109	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLBAFO_00735	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHOLBAFO_00736	8.8e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HHOLBAFO_00737	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHOLBAFO_00738	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHOLBAFO_00739	4.92e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHOLBAFO_00740	7.88e-233	camS	-	-	S	-	-	-	sex pheromone
HHOLBAFO_00741	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHOLBAFO_00742	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HHOLBAFO_00743	4.32e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HHOLBAFO_00744	9.17e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHOLBAFO_00745	9.5e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HHOLBAFO_00746	6.08e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HHOLBAFO_00747	5.47e-259	-	-	-	S	-	-	-	interspecies interaction between organisms
HHOLBAFO_00748	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HHOLBAFO_00749	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHOLBAFO_00750	2.6e-184	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHOLBAFO_00751	2.37e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHOLBAFO_00752	8.38e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHOLBAFO_00753	2.91e-191	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHOLBAFO_00754	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HHOLBAFO_00755	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOLBAFO_00756	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHOLBAFO_00757	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHOLBAFO_00758	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HHOLBAFO_00759	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHOLBAFO_00760	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHOLBAFO_00761	1.36e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHOLBAFO_00762	3.5e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HHOLBAFO_00763	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HHOLBAFO_00764	3.59e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHOLBAFO_00765	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHOLBAFO_00766	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHOLBAFO_00767	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHOLBAFO_00768	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHOLBAFO_00769	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHOLBAFO_00770	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHOLBAFO_00771	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHOLBAFO_00772	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHOLBAFO_00773	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HHOLBAFO_00774	2.29e-97	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHOLBAFO_00775	2.91e-148	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHOLBAFO_00776	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHOLBAFO_00777	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHOLBAFO_00778	1.35e-202	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHOLBAFO_00779	1.6e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHOLBAFO_00780	3.16e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HHOLBAFO_00781	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHOLBAFO_00782	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HHOLBAFO_00783	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHOLBAFO_00784	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHOLBAFO_00785	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHOLBAFO_00786	1.77e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
HHOLBAFO_00787	6.09e-275	-	-	-	-	-	-	-	-
HHOLBAFO_00788	2.4e-172	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HHOLBAFO_00789	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOLBAFO_00790	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOLBAFO_00791	4.92e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLBAFO_00792	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHOLBAFO_00793	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HHOLBAFO_00794	4.68e-40	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HHOLBAFO_00795	1.32e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HHOLBAFO_00796	6.3e-243	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HHOLBAFO_00797	3.3e-23	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HHOLBAFO_00798	6.23e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HHOLBAFO_00800	9.28e-171	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_00801	3.6e-191	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHOLBAFO_00802	1.09e-228	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HHOLBAFO_00803	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HHOLBAFO_00804	1.35e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HHOLBAFO_00805	3.38e-140	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HHOLBAFO_00806	7.8e-107	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HHOLBAFO_00807	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHOLBAFO_00808	2.18e-216	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HHOLBAFO_00809	8.41e-235	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HHOLBAFO_00810	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HHOLBAFO_00811	3.29e-146	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HHOLBAFO_00812	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HHOLBAFO_00813	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HHOLBAFO_00814	2.84e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HHOLBAFO_00815	1.05e-93	-	-	-	F	-	-	-	Nudix hydrolase
HHOLBAFO_00816	3.22e-135	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HHOLBAFO_00817	2.97e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HHOLBAFO_00818	4.69e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HHOLBAFO_00819	1.07e-211	-	-	-	-	-	-	-	-
HHOLBAFO_00820	3.38e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HHOLBAFO_00821	3.47e-121	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HHOLBAFO_00822	3.58e-311	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HHOLBAFO_00823	1.24e-149	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HHOLBAFO_00824	4.62e-104	-	-	-	-	-	-	-	-
HHOLBAFO_00826	2.7e-234	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HHOLBAFO_00827	3.98e-153	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HHOLBAFO_00828	2.1e-177	-	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HHOLBAFO_00829	1.42e-133	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_00830	3.39e-127	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HHOLBAFO_00831	6.09e-68	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HHOLBAFO_00832	0.0	-	-	-	E	-	-	-	amino acid
HHOLBAFO_00833	2.92e-172	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HHOLBAFO_00834	1.57e-261	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HHOLBAFO_00835	5.45e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHOLBAFO_00836	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HHOLBAFO_00837	1.45e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HHOLBAFO_00838	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHOLBAFO_00839	1.93e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HHOLBAFO_00840	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHOLBAFO_00841	1.5e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
HHOLBAFO_00842	3.4e-136	-	-	-	K	-	-	-	acetyltransferase
HHOLBAFO_00843	4.62e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HHOLBAFO_00864	3.76e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHOLBAFO_00865	2.07e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HHOLBAFO_00866	8.66e-256	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HHOLBAFO_00867	1.58e-145	yjbH	-	-	Q	-	-	-	Thioredoxin
HHOLBAFO_00868	3.81e-156	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HHOLBAFO_00869	2.61e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHOLBAFO_00870	5.39e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HHOLBAFO_00871	2.11e-248	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HHOLBAFO_00872	1.2e-202	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HHOLBAFO_00873	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHOLBAFO_00874	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HHOLBAFO_00875	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HHOLBAFO_00876	9.82e-76	-	-	-	-	-	-	-	-
HHOLBAFO_00877	7.65e-104	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HHOLBAFO_00878	8.91e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHOLBAFO_00879	2.46e-29	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HHOLBAFO_00880	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HHOLBAFO_00881	5.43e-228	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHOLBAFO_00882	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHOLBAFO_00883	2.81e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHOLBAFO_00884	4.1e-188	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHOLBAFO_00885	1.81e-295	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHOLBAFO_00886	3.01e-292	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHOLBAFO_00887	1.5e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHOLBAFO_00888	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HHOLBAFO_00889	3.4e-184	ylmH	-	-	S	-	-	-	S4 domain protein
HHOLBAFO_00890	1.46e-141	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HHOLBAFO_00892	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHOLBAFO_00893	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HHOLBAFO_00894	1.28e-126	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HHOLBAFO_00895	2.68e-08	-	-	-	-	-	-	-	-
HHOLBAFO_00896	3.96e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHOLBAFO_00897	4.55e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HHOLBAFO_00898	3.43e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHOLBAFO_00899	0.0	-	-	-	S	-	-	-	amidohydrolase
HHOLBAFO_00900	1.26e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HHOLBAFO_00901	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HHOLBAFO_00902	9.37e-159	-	-	-	S	-	-	-	repeat protein
HHOLBAFO_00903	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHOLBAFO_00904	4.45e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHOLBAFO_00905	2.39e-98	-	-	-	P	-	-	-	ArsC family
HHOLBAFO_00906	3.3e-236	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HHOLBAFO_00907	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HHOLBAFO_00908	2.49e-97	-	-	-	-	-	-	-	-
HHOLBAFO_00909	8.59e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHOLBAFO_00910	5.2e-64	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HHOLBAFO_00911	1.96e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HHOLBAFO_00912	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HHOLBAFO_00913	3.64e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HHOLBAFO_00914	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HHOLBAFO_00915	1.81e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HHOLBAFO_00916	5.91e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHOLBAFO_00917	9.31e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HHOLBAFO_00918	1.34e-122	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HHOLBAFO_00919	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HHOLBAFO_00920	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HHOLBAFO_00921	1.63e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HHOLBAFO_00922	7.63e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HHOLBAFO_00923	3.27e-123	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HHOLBAFO_00924	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHOLBAFO_00925	1.3e-262	yacL	-	-	S	-	-	-	domain protein
HHOLBAFO_00926	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHOLBAFO_00927	1.94e-129	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HHOLBAFO_00928	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HHOLBAFO_00929	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHOLBAFO_00930	4.11e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHOLBAFO_00931	1.31e-133	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HHOLBAFO_00932	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HHOLBAFO_00933	1.01e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHOLBAFO_00934	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HHOLBAFO_00935	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHOLBAFO_00936	2.78e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHOLBAFO_00937	3.15e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HHOLBAFO_00938	6.43e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHOLBAFO_00939	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHOLBAFO_00940	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HHOLBAFO_00941	4.87e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HHOLBAFO_00942	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HHOLBAFO_00943	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HHOLBAFO_00944	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HHOLBAFO_00945	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HHOLBAFO_00946	8.56e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHOLBAFO_00947	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHOLBAFO_00948	1.28e-45	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HHOLBAFO_00949	1.14e-107	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHOLBAFO_00951	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHOLBAFO_00952	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHOLBAFO_00953	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHOLBAFO_00954	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HHOLBAFO_00955	6.36e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHOLBAFO_00956	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HHOLBAFO_00957	6.77e-247	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HHOLBAFO_00958	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HHOLBAFO_00959	2.83e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHOLBAFO_00960	1.91e-187	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HHOLBAFO_00961	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HHOLBAFO_00962	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HHOLBAFO_00963	1.86e-218	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HHOLBAFO_00964	1.66e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HHOLBAFO_00965	6.43e-202	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HHOLBAFO_00966	8.46e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHOLBAFO_00967	4.08e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HHOLBAFO_00968	1.99e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HHOLBAFO_00969	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HHOLBAFO_00970	1.74e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HHOLBAFO_00971	1.73e-269	arcT	-	-	E	-	-	-	Aminotransferase
HHOLBAFO_00972	1.13e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HHOLBAFO_00973	1.12e-142	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HHOLBAFO_00974	2.87e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHOLBAFO_00975	3.82e-23	-	-	-	-	-	-	-	-
HHOLBAFO_00976	7.58e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHOLBAFO_00977	4.22e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HHOLBAFO_00978	1.39e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHOLBAFO_00979	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHOLBAFO_00980	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HHOLBAFO_00981	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HHOLBAFO_00982	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HHOLBAFO_00983	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHOLBAFO_00984	1.28e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHOLBAFO_00985	2.02e-140	-	-	-	-	-	-	-	-
HHOLBAFO_00986	1.07e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHOLBAFO_00987	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HHOLBAFO_00988	1.71e-104	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HHOLBAFO_00989	5.29e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLBAFO_00990	9.43e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HHOLBAFO_00991	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HHOLBAFO_00992	2.67e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHOLBAFO_00993	1.61e-149	ybbR	-	-	S	-	-	-	YbbR-like protein
HHOLBAFO_00994	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHOLBAFO_00995	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHOLBAFO_00996	2.55e-68	-	-	-	-	-	-	-	-
HHOLBAFO_00997	1.36e-261	oatA	-	-	I	-	-	-	Acyltransferase
HHOLBAFO_00998	3.38e-190	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HHOLBAFO_00999	1.15e-106	lytE	-	-	M	-	-	-	Lysin motif
HHOLBAFO_01000	2.83e-221	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HHOLBAFO_01001	6.46e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLBAFO_01002	6.68e-165	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HHOLBAFO_01003	6.07e-189	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HHOLBAFO_01004	6.93e-114	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HHOLBAFO_01005	2.9e-63	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HHOLBAFO_01006	2.88e-48	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HHOLBAFO_01007	1.17e-66	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HHOLBAFO_01008	2.22e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HHOLBAFO_01009	1.95e-163	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HHOLBAFO_01010	3.23e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HHOLBAFO_01011	7.33e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HHOLBAFO_01013	3.82e-168	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HHOLBAFO_01014	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HHOLBAFO_01015	3.54e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HHOLBAFO_01016	2.12e-274	xylR	-	-	GK	-	-	-	ROK family
HHOLBAFO_01017	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HHOLBAFO_01018	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HHOLBAFO_01019	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
HHOLBAFO_01020	0.000206	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLBAFO_01021	6.87e-87	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLBAFO_01022	2.57e-254	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HHOLBAFO_01023	6.06e-134	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HHOLBAFO_01024	4.69e-29	-	-	-	G	-	-	-	Major Facilitator
HHOLBAFO_01025	6.17e-236	-	-	-	G	-	-	-	Major Facilitator
HHOLBAFO_01026	8.12e-37	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HHOLBAFO_01027	1.28e-78	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
HHOLBAFO_01028	9.46e-87	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HHOLBAFO_01029	1.07e-274	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HHOLBAFO_01030	3.14e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HHOLBAFO_01031	5.17e-93	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
HHOLBAFO_01032	6.13e-107	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HHOLBAFO_01033	3.85e-89	-	-	-	-	-	-	-	-
HHOLBAFO_01034	5.78e-81	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HHOLBAFO_01035	5.55e-48	-	-	-	M	-	-	-	biosynthesis protein
HHOLBAFO_01036	2.33e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HHOLBAFO_01037	2.45e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HHOLBAFO_01038	1.13e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HHOLBAFO_01040	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HHOLBAFO_01041	2.78e-190	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HHOLBAFO_01042	3.62e-189	XK27_08315	-	-	M	-	-	-	Sulfatase
HHOLBAFO_01043	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HHOLBAFO_01044	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HHOLBAFO_01045	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HHOLBAFO_01046	1.38e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HHOLBAFO_01048	8.28e-308	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HHOLBAFO_01049	2.18e-243	mocA	-	-	S	-	-	-	Oxidoreductase
HHOLBAFO_01050	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HHOLBAFO_01051	1.8e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HHOLBAFO_01052	3.71e-205	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HHOLBAFO_01053	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HHOLBAFO_01054	4.79e-176	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HHOLBAFO_01055	1.43e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HHOLBAFO_01056	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HHOLBAFO_01057	2.41e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HHOLBAFO_01058	2.11e-134	-	-	-	-	-	-	-	-
HHOLBAFO_01059	2.09e-272	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HHOLBAFO_01060	1.39e-130	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HHOLBAFO_01061	1.47e-18	-	-	-	K	-	-	-	Transcriptional regulator
HHOLBAFO_01063	1.82e-172	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HHOLBAFO_01064	4.03e-125	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHOLBAFO_01065	4.53e-132	-	-	-	S	-	-	-	CAAX protease self-immunity
HHOLBAFO_01067	1.21e-145	-	-	-	Q	-	-	-	Methyltransferase domain
HHOLBAFO_01068	1.11e-97	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HHOLBAFO_01069	3.03e-66	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
HHOLBAFO_01070	7.65e-39	-	-	-	S	ko:K08987	-	ko00000	membrane
HHOLBAFO_01071	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HHOLBAFO_01072	6.44e-115	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HHOLBAFO_01073	1.32e-95	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
HHOLBAFO_01075	3.4e-244	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HHOLBAFO_01076	1.86e-181	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HHOLBAFO_01078	2.48e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HHOLBAFO_01079	9.99e-145	-	-	-	-	-	-	-	-
HHOLBAFO_01080	6.79e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HHOLBAFO_01081	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
HHOLBAFO_01082	6.09e-50	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HHOLBAFO_01083	2.73e-60	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
HHOLBAFO_01084	4.36e-67	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HHOLBAFO_01085	2.44e-96	-	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
HHOLBAFO_01086	3.5e-80	-	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHOLBAFO_01087	2.6e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLBAFO_01088	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_01089	1.69e-72	-	-	-	S	-	-	-	FMN_bind
HHOLBAFO_01090	1.46e-31	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHOLBAFO_01091	8.92e-35	-	-	-	M	-	-	-	Rib/alpha-like repeat
HHOLBAFO_01092	2.01e-292	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HHOLBAFO_01093	1.22e-124	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_01094	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHOLBAFO_01095	1.21e-296	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHOLBAFO_01096	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HHOLBAFO_01097	1.11e-67	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HHOLBAFO_01098	6.65e-196	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HHOLBAFO_01099	2.61e-31	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HHOLBAFO_01100	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HHOLBAFO_01101	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHOLBAFO_01103	3.19e-194	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HHOLBAFO_01104	9.26e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HHOLBAFO_01105	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HHOLBAFO_01106	1.1e-260	-	-	-	EGP	-	-	-	Major Facilitator
HHOLBAFO_01107	2.15e-97	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
HHOLBAFO_01108	1.94e-168	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HHOLBAFO_01109	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
HHOLBAFO_01110	5.88e-257	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HHOLBAFO_01111	5.28e-139	-	-	-	L	-	-	-	Helix-turn-helix domain
HHOLBAFO_01112	4.52e-201	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HHOLBAFO_01113	2.56e-235	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
HHOLBAFO_01114	5.03e-141	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
HHOLBAFO_01115	4.87e-166	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
HHOLBAFO_01116	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HHOLBAFO_01117	3.21e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHOLBAFO_01118	1.59e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HHOLBAFO_01119	3.49e-169	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HHOLBAFO_01120	3.88e-22	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLBAFO_01121	6.2e-56	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLBAFO_01122	4.89e-105	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHOLBAFO_01123	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HHOLBAFO_01124	2.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HHOLBAFO_01125	3.59e-134	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HHOLBAFO_01126	1.09e-218	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HHOLBAFO_01127	1.4e-53	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HHOLBAFO_01128	1.85e-126	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HHOLBAFO_01129	2.84e-263	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHOLBAFO_01130	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHOLBAFO_01131	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HHOLBAFO_01132	3.59e-240	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HHOLBAFO_01133	3.06e-199	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HHOLBAFO_01134	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHOLBAFO_01135	5.17e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HHOLBAFO_01136	3.97e-102	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHOLBAFO_01137	3.53e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HHOLBAFO_01138	1.5e-84	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HHOLBAFO_01139	1.56e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HHOLBAFO_01140	7.47e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HHOLBAFO_01141	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HHOLBAFO_01142	9.37e-313	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HHOLBAFO_01143	7.04e-247	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HHOLBAFO_01144	2.06e-188	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HHOLBAFO_01145	7.6e-215	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HHOLBAFO_01146	2.25e-215	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HHOLBAFO_01147	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HHOLBAFO_01149	3.19e-202	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HHOLBAFO_01150	1.07e-245	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HHOLBAFO_01152	3.54e-195	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLBAFO_01153	1.19e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_01154	1.32e-146	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HHOLBAFO_01155	2.67e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HHOLBAFO_01157	2.91e-191	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HHOLBAFO_01158	8.35e-142	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HHOLBAFO_01159	1.73e-92	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLBAFO_01160	7.96e-169	tcyC2	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HHOLBAFO_01161	7.47e-235	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
HHOLBAFO_01163	1.72e-266	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HHOLBAFO_01164	1.56e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HHOLBAFO_01165	2.39e-107	-	-	-	K	-	-	-	Transcriptional regulator
HHOLBAFO_01166	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHOLBAFO_01167	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHOLBAFO_01168	1.72e-75	-	-	-	-	-	-	-	-
HHOLBAFO_01169	1.61e-169	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHOLBAFO_01170	3.03e-230	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HHOLBAFO_01171	1.33e-69	-	-	-	-	-	-	-	-
HHOLBAFO_01173	1.03e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HHOLBAFO_01174	1.01e-272	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HHOLBAFO_01175	5.09e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHOLBAFO_01176	1.62e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HHOLBAFO_01177	2.11e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HHOLBAFO_01178	2.94e-148	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HHOLBAFO_01179	1.62e-174	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HHOLBAFO_01180	8.95e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HHOLBAFO_01181	1.28e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HHOLBAFO_01182	5.63e-196	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHOLBAFO_01183	6.84e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HHOLBAFO_01184	5.35e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHOLBAFO_01185	1.01e-180	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHOLBAFO_01186	1.66e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HHOLBAFO_01187	2.4e-295	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HHOLBAFO_01188	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHOLBAFO_01189	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHOLBAFO_01190	3.26e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HHOLBAFO_01191	5.88e-176	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HHOLBAFO_01192	2.87e-263	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HHOLBAFO_01193	8.62e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHOLBAFO_01194	4.36e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HHOLBAFO_01195	7.69e-84	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HHOLBAFO_01196	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HHOLBAFO_01197	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HHOLBAFO_01198	3.87e-282	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HHOLBAFO_01199	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HHOLBAFO_01200	1.3e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HHOLBAFO_01201	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHOLBAFO_01202	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHOLBAFO_01203	1.86e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHOLBAFO_01204	5.91e-233	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HHOLBAFO_01205	1.57e-313	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HHOLBAFO_01206	1.57e-196	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HHOLBAFO_01207	8.34e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HHOLBAFO_01208	8.92e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HHOLBAFO_01209	1.49e-165	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHOLBAFO_01210	9.05e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHOLBAFO_01211	4.63e-173	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HHOLBAFO_01212	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHOLBAFO_01213	2.09e-50	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HHOLBAFO_01214	2.63e-219	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HHOLBAFO_01215	1.81e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HHOLBAFO_01217	7.24e-97	uspA3	-	-	T	-	-	-	universal stress protein
HHOLBAFO_01218	3.62e-77	-	-	-	-	-	-	-	-
HHOLBAFO_01219	4.83e-10	-	-	-	-	-	-	-	-
HHOLBAFO_01220	1.84e-201	-	-	-	-	-	-	-	-
HHOLBAFO_01221	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
HHOLBAFO_01222	1.91e-233	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HHOLBAFO_01223	9.85e-30	-	-	-	O	-	-	-	OsmC-like protein
HHOLBAFO_01224	2.04e-34	-	-	-	O	-	-	-	OsmC-like protein
HHOLBAFO_01225	5.56e-246	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HHOLBAFO_01226	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HHOLBAFO_01227	3.57e-22	-	-	-	-	-	-	-	-
HHOLBAFO_01228	5.87e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HHOLBAFO_01229	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_01230	6.78e-130	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HHOLBAFO_01231	2.8e-230	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HHOLBAFO_01232	1.24e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HHOLBAFO_01233	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HHOLBAFO_01234	1.52e-43	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HHOLBAFO_01235	1.09e-127	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HHOLBAFO_01236	3.13e-141	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
HHOLBAFO_01237	6.07e-40	-	-	-	-	-	-	-	-
HHOLBAFO_01238	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHOLBAFO_01239	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HHOLBAFO_01240	4.81e-191	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HHOLBAFO_01241	3.73e-300	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HHOLBAFO_01242	5.35e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HHOLBAFO_01243	3.91e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HHOLBAFO_01244	1.01e-182	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HHOLBAFO_01245	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HHOLBAFO_01246	1.58e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHOLBAFO_01247	9.89e-207	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HHOLBAFO_01248	9.83e-235	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HHOLBAFO_01249	5.69e-234	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_01250	3.39e-274	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
HHOLBAFO_01251	3.56e-115	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHOLBAFO_01252	1.3e-75	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HHOLBAFO_01253	2.2e-97	-	-	-	-	-	-	-	-
HHOLBAFO_01254	3.39e-84	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHOLBAFO_01255	6.48e-71	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHOLBAFO_01256	1.5e-74	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHOLBAFO_01257	2.15e-14	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
HHOLBAFO_01258	1.77e-216	-	-	-	G	-	-	-	Major Facilitator Superfamily
HHOLBAFO_01260	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HHOLBAFO_01262	2.24e-196	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HHOLBAFO_01263	1.3e-203	-	-	-	GM	-	-	-	NAD(P)H-binding
HHOLBAFO_01264	5.71e-201	-	-	-	S	-	-	-	Alpha beta hydrolase
HHOLBAFO_01265	7.61e-299	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HHOLBAFO_01267	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HHOLBAFO_01268	7.43e-16	-	-	-	-	-	-	-	-
HHOLBAFO_01269	3.46e-65	-	-	-	-	-	-	-	-
HHOLBAFO_01270	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HHOLBAFO_01272	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHOLBAFO_01273	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HHOLBAFO_01274	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HHOLBAFO_01275	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HHOLBAFO_01276	1.34e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HHOLBAFO_01277	1.85e-301	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHOLBAFO_01278	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHOLBAFO_01279	6.98e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HHOLBAFO_01280	8.81e-202	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
HHOLBAFO_01281	1.48e-270	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HHOLBAFO_01282	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HHOLBAFO_01283	3.25e-274	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HHOLBAFO_01284	2.72e-10	-	-	-	-	-	-	-	-
HHOLBAFO_01285	1.63e-195	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HHOLBAFO_01286	3.53e-20	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HHOLBAFO_01287	4.74e-23	-	-	-	-	-	-	-	-
HHOLBAFO_01288	1.39e-40	-	-	-	S	-	-	-	Transglycosylase associated protein
HHOLBAFO_01289	8.47e-106	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HHOLBAFO_01290	7.19e-31	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
HHOLBAFO_01291	6.51e-122	-	-	-	-	-	-	-	-
HHOLBAFO_01292	2.21e-42	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOLBAFO_01293	5.8e-306	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HHOLBAFO_01294	2.98e-246	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HHOLBAFO_01295	5.34e-26	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HHOLBAFO_01296	1.86e-24	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
HHOLBAFO_01297	3.25e-102	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HHOLBAFO_01298	3.43e-281	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_01299	1.14e-255	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HHOLBAFO_01300	4.12e-135	-	-	-	C	-	-	-	aldo keto reductase
HHOLBAFO_01301	1.9e-138	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HHOLBAFO_01303	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHOLBAFO_01304	1.56e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHOLBAFO_01305	5.11e-67	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HHOLBAFO_01306	4.55e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HHOLBAFO_01307	3.65e-33	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHOLBAFO_01308	6.11e-48	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHOLBAFO_01309	2.08e-75	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHOLBAFO_01310	5.22e-259	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHOLBAFO_01311	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HHOLBAFO_01312	9.76e-87	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHOLBAFO_01313	1.16e-242	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHOLBAFO_01314	6.7e-81	-	-	-	-	-	-	-	-
HHOLBAFO_01315	2.36e-216	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOLBAFO_01316	1.03e-125	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HHOLBAFO_01317	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HHOLBAFO_01318	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HHOLBAFO_01319	6.76e-222	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HHOLBAFO_01320	1.3e-194	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HHOLBAFO_01321	2.36e-118	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HHOLBAFO_01322	1.2e-122	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HHOLBAFO_01323	1.07e-129	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HHOLBAFO_01324	1.95e-119	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOLBAFO_01325	2.07e-260	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHOLBAFO_01326	5.8e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HHOLBAFO_01327	6.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HHOLBAFO_01328	5.33e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HHOLBAFO_01329	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HHOLBAFO_01330	1.91e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HHOLBAFO_01331	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HHOLBAFO_01332	4.14e-173	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HHOLBAFO_01333	1.21e-186	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HHOLBAFO_01334	1.65e-243	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HHOLBAFO_01335	2.7e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HHOLBAFO_01336	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HHOLBAFO_01337	3.31e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHOLBAFO_01338	7.6e-145	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HHOLBAFO_01339	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHOLBAFO_01340	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HHOLBAFO_01341	4.18e-269	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
HHOLBAFO_01342	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
HHOLBAFO_01343	1.05e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HHOLBAFO_01344	3.1e-242	arcT	-	-	E	-	-	-	Dipeptidase
HHOLBAFO_01345	8.65e-254	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HHOLBAFO_01346	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HHOLBAFO_01348	1.01e-99	-	-	-	-	-	-	-	-
HHOLBAFO_01349	6.16e-235	-	-	-	-	-	-	-	-
HHOLBAFO_01350	6.13e-164	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HHOLBAFO_01351	2.15e-132	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
HHOLBAFO_01352	0.0	-	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HHOLBAFO_01353	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHOLBAFO_01354	1.71e-241	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HHOLBAFO_01355	2.97e-110	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HHOLBAFO_01356	1.74e-292	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HHOLBAFO_01357	1.48e-105	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HHOLBAFO_01358	5.41e-123	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HHOLBAFO_01359	6.94e-54	-	-	-	-	-	-	-	-
HHOLBAFO_01360	3.51e-101	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	GAF domain
HHOLBAFO_01361	7.36e-234	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HHOLBAFO_01362	4.49e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HHOLBAFO_01363	2.83e-53	-	-	-	-	-	-	-	-
HHOLBAFO_01364	9.43e-233	-	-	-	-	-	-	-	-
HHOLBAFO_01365	9.59e-215	-	-	-	H	-	-	-	geranyltranstransferase activity
HHOLBAFO_01367	1.69e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHOLBAFO_01368	1.85e-207	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HHOLBAFO_01369	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HHOLBAFO_01370	2.31e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
HHOLBAFO_01371	1.67e-249	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HHOLBAFO_01372	1.12e-45	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HHOLBAFO_01373	1.6e-94	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HHOLBAFO_01374	4.13e-87	-	-	-	S	-	-	-	Flavodoxin
HHOLBAFO_01375	8.45e-218	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLBAFO_01376	2.6e-183	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HHOLBAFO_01377	2.57e-291	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HHOLBAFO_01378	8.55e-71	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HHOLBAFO_01379	1.04e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
HHOLBAFO_01380	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HHOLBAFO_01381	1.86e-180	-	-	-	EG	-	-	-	EamA-like transporter family
HHOLBAFO_01382	0.0	-	-	-	L	-	-	-	DNA helicase
HHOLBAFO_01383	7.63e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HHOLBAFO_01384	5.07e-282	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HHOLBAFO_01385	9.16e-240	-	-	-	-	-	-	-	-
HHOLBAFO_01386	9.4e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HHOLBAFO_01387	1.95e-269	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HHOLBAFO_01388	3.89e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HHOLBAFO_01389	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHOLBAFO_01390	7.76e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HHOLBAFO_01391	8.88e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHOLBAFO_01392	8.42e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHOLBAFO_01393	7.82e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HHOLBAFO_01394	2.73e-210	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HHOLBAFO_01395	1.29e-119	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HHOLBAFO_01396	2.81e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HHOLBAFO_01397	6.12e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HHOLBAFO_01398	2.72e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHOLBAFO_01399	1.73e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHOLBAFO_01400	1.89e-73	-	-	-	-	-	-	-	-
HHOLBAFO_01401	7.92e-182	yidA	-	-	S	-	-	-	hydrolase
HHOLBAFO_01402	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HHOLBAFO_01403	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HHOLBAFO_01404	9.7e-86	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHOLBAFO_01405	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHOLBAFO_01406	5.94e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHOLBAFO_01407	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HHOLBAFO_01408	8.58e-07	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HHOLBAFO_01409	6.13e-10	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HHOLBAFO_01410	5.61e-92	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HHOLBAFO_01411	2.56e-156	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HHOLBAFO_01412	2.3e-239	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHOLBAFO_01413	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHOLBAFO_01414	5.47e-94	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HHOLBAFO_01415	9.92e-26	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HHOLBAFO_01416	5.72e-130	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HHOLBAFO_01417	1.65e-213	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHOLBAFO_01418	8.46e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HHOLBAFO_01419	9.07e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_01421	3.24e-313	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HHOLBAFO_01422	4.44e-208	-	-	-	EG	-	-	-	EamA-like transporter family
HHOLBAFO_01423	1.07e-169	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHOLBAFO_01424	5.27e-179	-	-	-	G	-	-	-	MucBP domain
HHOLBAFO_01425	2.31e-125	-	-	-	S	-	-	-	Pfam:DUF3816
HHOLBAFO_01426	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHOLBAFO_01427	2.03e-141	pncA	-	-	Q	-	-	-	Isochorismatase family
HHOLBAFO_01428	4.63e-162	-	-	-	F	-	-	-	NUDIX domain
HHOLBAFO_01429	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HHOLBAFO_01430	5.36e-07	-	-	-	-	-	-	-	-
HHOLBAFO_01431	4.32e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HHOLBAFO_01432	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHOLBAFO_01433	1.8e-290	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HHOLBAFO_01434	6.07e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HHOLBAFO_01435	1.68e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHOLBAFO_01436	3.28e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HHOLBAFO_01437	2.08e-12	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HHOLBAFO_01438	3.63e-19	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HHOLBAFO_01439	3.72e-34	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HHOLBAFO_01440	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HHOLBAFO_01441	6.63e-122	-	-	-	V	-	-	-	VanZ like family
HHOLBAFO_01442	1.15e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HHOLBAFO_01443	6.24e-78	-	-	-	-	-	-	-	-
HHOLBAFO_01444	5.43e-231	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HHOLBAFO_01445	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HHOLBAFO_01446	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HHOLBAFO_01447	4.46e-135	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
HHOLBAFO_01448	1.72e-36	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
HHOLBAFO_01450	1.31e-104	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HHOLBAFO_01452	1.71e-105	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HHOLBAFO_01453	4.58e-54	-	-	-	-	-	-	-	-
HHOLBAFO_01454	1.04e-218	-	-	-	GK	-	-	-	ROK family
HHOLBAFO_01455	1.68e-163	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
HHOLBAFO_01456	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HHOLBAFO_01457	3.13e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HHOLBAFO_01458	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHOLBAFO_01459	1.73e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHOLBAFO_01460	6.33e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHOLBAFO_01462	5.57e-300	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HHOLBAFO_01463	1.21e-89	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HHOLBAFO_01464	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLBAFO_01465	7.39e-39	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HHOLBAFO_01466	7.35e-17	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLBAFO_01467	1.51e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HHOLBAFO_01469	5.89e-20	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HHOLBAFO_01470	2.44e-266	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HHOLBAFO_01471	5.78e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HHOLBAFO_01472	1.93e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HHOLBAFO_01473	1.81e-309	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HHOLBAFO_01474	8.91e-229	-	-	-	K	-	-	-	WYL domain
HHOLBAFO_01475	3.96e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HHOLBAFO_01476	2.65e-07	-	-	-	-	-	-	-	-
HHOLBAFO_01478	1.21e-44	-	-	-	-	-	-	-	-
HHOLBAFO_01479	7.83e-142	yicL	-	-	EG	-	-	-	EamA-like transporter family
HHOLBAFO_01480	7.84e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HHOLBAFO_01481	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HHOLBAFO_01482	4.33e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLBAFO_01483	1.41e-206	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HHOLBAFO_01484	5.17e-271	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HHOLBAFO_01485	1e-233	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HHOLBAFO_01486	7.03e-30	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HHOLBAFO_01487	4.77e-116	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HHOLBAFO_01488	2.09e-243	flp	-	-	V	-	-	-	Beta-lactamase
HHOLBAFO_01489	1.31e-289	-	-	-	-	-	-	-	-
HHOLBAFO_01491	4.18e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HHOLBAFO_01492	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHOLBAFO_01493	5.3e-207	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HHOLBAFO_01494	5.3e-207	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HHOLBAFO_01495	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HHOLBAFO_01497	3.39e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HHOLBAFO_01498	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHOLBAFO_01499	1e-64	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HHOLBAFO_01500	6.34e-224	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HHOLBAFO_01501	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHOLBAFO_01502	3.84e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
HHOLBAFO_01503	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHOLBAFO_01504	1.29e-296	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHOLBAFO_01505	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHOLBAFO_01506	5.13e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HHOLBAFO_01507	5.48e-70	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HHOLBAFO_01509	4.63e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_01510	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHOLBAFO_01511	7.64e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHOLBAFO_01512	8.64e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHOLBAFO_01513	1.06e-198	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHOLBAFO_01514	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HHOLBAFO_01515	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHOLBAFO_01516	6.96e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HHOLBAFO_01517	7.82e-239	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_01518	6.15e-193	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HHOLBAFO_01519	1.24e-57	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HHOLBAFO_01520	6.63e-127	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HHOLBAFO_01521	1.97e-57	-	-	-	S	-	-	-	Protein conserved in bacteria
HHOLBAFO_01522	1.6e-14	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HHOLBAFO_01523	4.53e-32	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HHOLBAFO_01524	1.56e-67	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HHOLBAFO_01528	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHOLBAFO_01529	6.93e-154	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HHOLBAFO_01530	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HHOLBAFO_01531	3.31e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HHOLBAFO_01532	3.06e-203	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HHOLBAFO_01533	1.63e-257	-	-	-	-	-	-	-	-
HHOLBAFO_01534	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHOLBAFO_01535	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHOLBAFO_01537	5.06e-145	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HHOLBAFO_01538	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HHOLBAFO_01539	4.01e-174	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HHOLBAFO_01540	2.76e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HHOLBAFO_01541	2.79e-253	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HHOLBAFO_01542	2.45e-100	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HHOLBAFO_01543	2.21e-42	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HHOLBAFO_01544	4.74e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHOLBAFO_01545	2.61e-100	yphH	-	-	S	-	-	-	Cupin domain
HHOLBAFO_01546	6.21e-241	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHOLBAFO_01547	4.21e-287	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HHOLBAFO_01548	3.56e-187	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HHOLBAFO_01549	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HHOLBAFO_01550	1.51e-147	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_01551	2.55e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HHOLBAFO_01552	9.57e-47	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HHOLBAFO_01553	2.26e-42	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HHOLBAFO_01554	9.13e-60	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HHOLBAFO_01555	3.32e-72	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HHOLBAFO_01557	5.41e-274	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HHOLBAFO_01558	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HHOLBAFO_01559	1.51e-281	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HHOLBAFO_01560	4.57e-32	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HHOLBAFO_01561	5.43e-137	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HHOLBAFO_01562	8.93e-185	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HHOLBAFO_01564	1.49e-276	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HHOLBAFO_01566	3.11e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HHOLBAFO_01567	1.14e-124	-	-	-	K	-	-	-	Virulence activator alpha C-term
HHOLBAFO_01568	1.13e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HHOLBAFO_01569	2.58e-40	-	-	-	S	-	-	-	SNARE associated Golgi protein
HHOLBAFO_01570	7.5e-302	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HHOLBAFO_01571	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHOLBAFO_01573	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HHOLBAFO_01574	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHOLBAFO_01575	2.21e-182	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HHOLBAFO_01576	3.66e-183	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HHOLBAFO_01577	5.65e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HHOLBAFO_01578	1.32e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HHOLBAFO_01579	3.43e-88	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HHOLBAFO_01580	4.78e-268	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HHOLBAFO_01581	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HHOLBAFO_01582	1.36e-243	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HHOLBAFO_01583	1.46e-87	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLBAFO_01584	2.23e-205	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HHOLBAFO_01585	1.85e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHOLBAFO_01586	9.86e-201	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HHOLBAFO_01587	2.06e-135	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHOLBAFO_01588	1.48e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HHOLBAFO_01589	1.1e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HHOLBAFO_01590	2.62e-58	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HHOLBAFO_01591	2.58e-36	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HHOLBAFO_01592	1.04e-82	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HHOLBAFO_01593	1.29e-280	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HHOLBAFO_01594	1.08e-65	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HHOLBAFO_01595	1.24e-151	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HHOLBAFO_01596	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HHOLBAFO_01597	4.02e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HHOLBAFO_01598	4.27e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HHOLBAFO_01599	1.13e-93	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHOLBAFO_01600	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HHOLBAFO_01601	1.26e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HHOLBAFO_01602	2.34e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HHOLBAFO_01603	3.99e-198	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HHOLBAFO_01604	9.65e-152	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HHOLBAFO_01605	8.51e-159	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HHOLBAFO_01606	2.93e-203	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HHOLBAFO_01608	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHOLBAFO_01610	1.74e-157	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
HHOLBAFO_01611	3.91e-126	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
HHOLBAFO_01612	5.28e-106	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
HHOLBAFO_01613	5.94e-143	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HHOLBAFO_01614	4.28e-60	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHOLBAFO_01615	1.94e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HHOLBAFO_01616	1.9e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HHOLBAFO_01617	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHOLBAFO_01618	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHOLBAFO_01619	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHOLBAFO_01620	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHOLBAFO_01621	5.83e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HHOLBAFO_01622	2.61e-147	-	-	-	S	-	-	-	(CBS) domain
HHOLBAFO_01623	2.29e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHOLBAFO_01624	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHOLBAFO_01625	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
HHOLBAFO_01626	2.4e-73	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HHOLBAFO_01627	2.74e-112	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HHOLBAFO_01628	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHOLBAFO_01629	3.01e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HHOLBAFO_01630	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHOLBAFO_01631	2.74e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHOLBAFO_01632	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHOLBAFO_01633	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HHOLBAFO_01635	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HHOLBAFO_01636	8.2e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HHOLBAFO_01637	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HHOLBAFO_01638	5.39e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHOLBAFO_01639	5.37e-36	-	-	-	S	-	-	-	Domain of unknown function DUF302
HHOLBAFO_01640	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HHOLBAFO_01641	9.88e-57	-	-	-	-	-	-	-	-
HHOLBAFO_01642	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HHOLBAFO_01643	1.62e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HHOLBAFO_01644	5.12e-285	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHOLBAFO_01645	2.1e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHOLBAFO_01646	1.26e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHOLBAFO_01647	3.23e-64	-	-	-	-	-	-	-	-
HHOLBAFO_01648	7.03e-125	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HHOLBAFO_01649	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HHOLBAFO_01650	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HHOLBAFO_01651	3.17e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HHOLBAFO_01652	3.91e-31	-	-	-	-	-	-	-	-
HHOLBAFO_01655	0.0	potE	-	-	E	-	-	-	Amino Acid
HHOLBAFO_01656	3.38e-175	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HHOLBAFO_01657	6.99e-285	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHOLBAFO_01658	3.01e-125	-	-	-	-	-	-	-	-
HHOLBAFO_01659	1.48e-151	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HHOLBAFO_01660	3.1e-138	-	-	-	I	-	-	-	PAP2 superfamily
HHOLBAFO_01661	7.63e-72	-	-	-	S	-	-	-	MazG-like family
HHOLBAFO_01662	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HHOLBAFO_01663	4.52e-176	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HHOLBAFO_01665	2.11e-87	-	-	-	-	-	-	-	-
HHOLBAFO_01666	1.12e-49	-	-	-	-	-	-	-	-
HHOLBAFO_01667	1.05e-149	-	-	-	-	-	-	-	-
HHOLBAFO_01668	1.69e-210	-	-	-	L	-	-	-	Z1 domain
HHOLBAFO_01669	1.36e-24	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HHOLBAFO_01673	4.7e-51	-	-	-	S	-	-	-	Cytochrome B5
HHOLBAFO_01674	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HHOLBAFO_01675	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HHOLBAFO_01676	1.97e-129	-	-	-	-	-	-	-	-
HHOLBAFO_01677	3.78e-167	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HHOLBAFO_01678	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOLBAFO_01679	1.45e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HHOLBAFO_01680	9.87e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLBAFO_01681	9.46e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHOLBAFO_01682	4.16e-297	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HHOLBAFO_01683	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HHOLBAFO_01684	3.29e-42	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HHOLBAFO_01685	3.46e-55	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HHOLBAFO_01686	1.48e-42	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HHOLBAFO_01687	1.15e-230	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HHOLBAFO_01688	2.59e-229	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HHOLBAFO_01689	4.07e-274	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHOLBAFO_01690	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HHOLBAFO_01691	6.78e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HHOLBAFO_01692	6.25e-268	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HHOLBAFO_01693	2.21e-229	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLBAFO_01694	9.64e-193	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HHOLBAFO_01695	3.73e-232	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HHOLBAFO_01696	8.41e-85	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HHOLBAFO_01697	2.19e-160	-	-	-	FH	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
HHOLBAFO_01698	1e-284	-	3.5.2.3, 3.5.2.5	-	F	ko:K01465,ko:K01466	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHOLBAFO_01699	2.14e-289	allC	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	Peptidase family M20/M25/M40
HHOLBAFO_01700	2.68e-160	ylbA	3.5.3.26	-	S	ko:K14977	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	protein, possibly involved in glyoxylate utilization
HHOLBAFO_01701	5.22e-255	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
HHOLBAFO_01702	2e-303	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
HHOLBAFO_01703	1.72e-271	-	-	-	C	-	-	-	Protein of unknown function (DUF1116)
HHOLBAFO_01704	1.13e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF2877)
HHOLBAFO_01705	8.04e-163	cpkA	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
HHOLBAFO_01706	3.24e-221	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HHOLBAFO_01707	4.35e-157	-	-	-	C	-	-	-	nitroreductase
HHOLBAFO_01708	1.19e-119	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HHOLBAFO_01709	3.18e-20	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HHOLBAFO_01710	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HHOLBAFO_01711	1.51e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HHOLBAFO_01712	1.31e-209	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHOLBAFO_01713	6.84e-227	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHOLBAFO_01714	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HHOLBAFO_01715	2.7e-68	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HHOLBAFO_01716	2.05e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHOLBAFO_01717	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHOLBAFO_01718	3.26e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHOLBAFO_01719	1.25e-165	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HHOLBAFO_01720	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HHOLBAFO_01721	9.05e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HHOLBAFO_01722	4.12e-50	-	-	-	-	-	-	-	-
HHOLBAFO_01723	0.0	ydaO	-	-	E	-	-	-	amino acid
HHOLBAFO_01724	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHOLBAFO_01725	1.64e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHOLBAFO_01726	3.83e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHOLBAFO_01727	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HHOLBAFO_01728	9.91e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HHOLBAFO_01729	1.5e-56	-	-	-	-	-	-	-	-
HHOLBAFO_01731	4.54e-301	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HHOLBAFO_01732	2.57e-180	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLBAFO_01733	1.38e-188	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLBAFO_01734	3.12e-193	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HHOLBAFO_01735	1.53e-128	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
HHOLBAFO_01736	0.0	-	-	-	M	-	-	-	Iron Transport-associated domain
HHOLBAFO_01737	7.54e-102	-	-	-	-	-	-	-	-
HHOLBAFO_01738	8.58e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHOLBAFO_01739	4.19e-150	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHOLBAFO_01740	6.69e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HHOLBAFO_01741	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HHOLBAFO_01742	8.88e-213	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HHOLBAFO_01743	3.86e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHOLBAFO_01744	2.69e-207	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HHOLBAFO_01745	1.07e-239	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HHOLBAFO_01746	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HHOLBAFO_01748	2.16e-103	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HHOLBAFO_01749	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HHOLBAFO_01750	1.91e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHOLBAFO_01751	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHOLBAFO_01752	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HHOLBAFO_01753	6.07e-205	-	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HHOLBAFO_01754	6.11e-148	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HHOLBAFO_01755	9.24e-94	-	-	-	S	-	-	-	Homeodomain-like domain
HHOLBAFO_01757	1.3e-126	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
HHOLBAFO_01758	3.39e-128	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HHOLBAFO_01759	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HHOLBAFO_01762	3.32e-135	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HHOLBAFO_01763	2.29e-101	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HHOLBAFO_01764	3.46e-110	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HHOLBAFO_01765	1.43e-88	-	-	-	M	-	-	-	LysM domain protein
HHOLBAFO_01766	1.41e-247	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HHOLBAFO_01767	5.31e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
HHOLBAFO_01768	9.88e-205	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HHOLBAFO_01769	1.22e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHOLBAFO_01770	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HHOLBAFO_01771	7.19e-142	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HHOLBAFO_01772	9.64e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HHOLBAFO_01773	5.43e-15	-	-	-	K	-	-	-	transcriptional regulator
HHOLBAFO_01775	1.93e-220	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHOLBAFO_01776	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HHOLBAFO_01777	8.95e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HHOLBAFO_01778	1.1e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HHOLBAFO_01779	5.09e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHOLBAFO_01780	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HHOLBAFO_01781	6.55e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHOLBAFO_01782	1.92e-91	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHOLBAFO_01783	7.65e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHOLBAFO_01784	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HHOLBAFO_01785	7.58e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HHOLBAFO_01786	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHOLBAFO_01787	4.39e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHOLBAFO_01788	4.1e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HHOLBAFO_01789	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHOLBAFO_01791	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HHOLBAFO_01792	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HHOLBAFO_01794	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HHOLBAFO_01795	4.67e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF998)
HHOLBAFO_01796	3.96e-97	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HHOLBAFO_01797	1.08e-112	-	-	-	K	-	-	-	FR47-like protein
HHOLBAFO_01798	2.94e-195	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HHOLBAFO_01799	1.27e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HHOLBAFO_01800	7.74e-202	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HHOLBAFO_01801	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
HHOLBAFO_01802	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HHOLBAFO_01803	4.05e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HHOLBAFO_01804	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HHOLBAFO_01805	9.21e-304	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HHOLBAFO_01806	1.5e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHOLBAFO_01807	1.76e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HHOLBAFO_01808	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HHOLBAFO_01809	3.4e-235	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HHOLBAFO_01810	5.65e-116	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
HHOLBAFO_01811	1.58e-196	-	-	-	EGP	-	-	-	Major Facilitator
HHOLBAFO_01812	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HHOLBAFO_01813	1.82e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HHOLBAFO_01814	1.77e-66	-	-	-	S	-	-	-	Cupredoxin-like domain
HHOLBAFO_01815	1.6e-223	-	-	-	-	-	-	-	-
HHOLBAFO_01816	5.74e-285	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HHOLBAFO_01817	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHOLBAFO_01818	9.19e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHOLBAFO_01819	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HHOLBAFO_01820	2.08e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HHOLBAFO_01821	2.57e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHOLBAFO_01822	6.61e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HHOLBAFO_01823	1.18e-35	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
HHOLBAFO_01824	1.13e-77	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
HHOLBAFO_01825	1.52e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HHOLBAFO_01826	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HHOLBAFO_01827	3.11e-166	-	-	-	-	-	-	-	-
HHOLBAFO_01828	1.21e-114	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHOLBAFO_01829	3.13e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HHOLBAFO_01830	1.33e-185	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HHOLBAFO_01831	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HHOLBAFO_01832	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
HHOLBAFO_01835	6.15e-07	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
HHOLBAFO_01836	2.76e-126	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HHOLBAFO_01838	1.29e-231	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HHOLBAFO_01839	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HHOLBAFO_01840	1.38e-120	-	-	-	-	-	-	-	-
HHOLBAFO_01842	1.81e-210	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HHOLBAFO_01843	3.3e-122	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHOLBAFO_01845	2.08e-219	yueF	-	-	S	-	-	-	AI-2E family transporter
HHOLBAFO_01846	1.89e-203	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HHOLBAFO_01847	4.14e-09	-	-	-	-	-	-	-	-
HHOLBAFO_01848	7.4e-74	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HHOLBAFO_01849	3.02e-35	yitW	-	-	S	-	-	-	DNA methyltransferase
HHOLBAFO_01850	7.62e-142	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HHOLBAFO_01851	5.72e-83	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HHOLBAFO_01854	2.07e-117	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HHOLBAFO_01855	8.35e-107	-	-	-	S	-	-	-	Carboxymuconolactone decarboxylase family
HHOLBAFO_01859	1.12e-23	-	-	-	-	-	-	-	-
HHOLBAFO_01861	1.49e-195	-	-	-	-	-	-	-	-
HHOLBAFO_01862	2.79e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHOLBAFO_01863	1.38e-251	-	-	-	S	-	-	-	Domain of unknown function (DUF4432)
HHOLBAFO_01864	4.27e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHOLBAFO_01865	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HHOLBAFO_01866	1.84e-238	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHOLBAFO_01867	0.0	potE	-	-	E	-	-	-	Amino Acid
HHOLBAFO_01868	7.18e-160	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HHOLBAFO_01869	1.01e-304	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HHOLBAFO_01870	2.75e-167	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HHOLBAFO_01871	1.45e-298	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HHOLBAFO_01872	1.56e-165	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HHOLBAFO_01873	4.65e-191	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HHOLBAFO_01874	1.45e-234	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
HHOLBAFO_01875	1.01e-143	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HHOLBAFO_01876	3.95e-250	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
HHOLBAFO_01877	6.93e-210	-	-	-	H	-	-	-	Acyl-protein synthetase, LuxE
HHOLBAFO_01878	2.4e-260	-	-	-	F	ko:K03458	-	ko00000	Permease
HHOLBAFO_01879	3.62e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HHOLBAFO_01880	1.93e-157	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HHOLBAFO_01881	3.22e-204	-	-	-	D	-	-	-	nuclear chromosome segregation
HHOLBAFO_01882	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HHOLBAFO_01883	5.56e-211	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HHOLBAFO_01886	3.15e-147	-	-	-	-	-	-	-	-
HHOLBAFO_01887	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HHOLBAFO_01888	9.14e-45	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HHOLBAFO_01889	3.7e-72	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HHOLBAFO_01890	1.2e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HHOLBAFO_01891	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HHOLBAFO_01892	1.18e-275	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HHOLBAFO_01893	5.08e-263	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HHOLBAFO_01894	1.12e-64	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HHOLBAFO_01895	1.68e-126	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HHOLBAFO_01896	1.85e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHOLBAFO_01897	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HHOLBAFO_01898	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HHOLBAFO_01899	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHOLBAFO_01900	2.06e-155	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HHOLBAFO_01901	3.15e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HHOLBAFO_01902	7.27e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HHOLBAFO_01903	1.46e-135	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HHOLBAFO_01904	2.58e-254	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHOLBAFO_01905	3.92e-58	-	-	-	C	-	-	-	FMN binding
HHOLBAFO_01906	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HHOLBAFO_01907	7.85e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HHOLBAFO_01908	6.69e-101	dltr	-	-	K	-	-	-	response regulator
HHOLBAFO_01909	3.62e-165	sptS	-	-	T	-	-	-	Histidine kinase
HHOLBAFO_01911	2.23e-197	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HHOLBAFO_01913	1.23e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HHOLBAFO_01915	9.78e-73	-	-	-	K	-	-	-	Transcriptional regulator
HHOLBAFO_01916	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HHOLBAFO_01917	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HHOLBAFO_01918	3.76e-176	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HHOLBAFO_01919	2.94e-135	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
HHOLBAFO_01920	4.53e-301	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HHOLBAFO_01921	6.01e-198	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HHOLBAFO_01922	1.79e-90	-	-	-	S	-	-	-	Protease prsW family
HHOLBAFO_01924	2.91e-114	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HHOLBAFO_01925	6e-06	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HHOLBAFO_01926	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHOLBAFO_01927	2.03e-272	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HHOLBAFO_01928	1.43e-227	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HHOLBAFO_01929	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HHOLBAFO_01930	7.46e-31	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HHOLBAFO_01932	0.000676	-	-	-	S	-	-	-	CsbD-like
HHOLBAFO_01933	4.49e-15	-	-	-	C	-	-	-	Aldo keto reductase
HHOLBAFO_01934	1.8e-48	-	-	-	C	-	-	-	Aldo keto reductase
HHOLBAFO_01935	8.67e-43	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HHOLBAFO_01937	8.01e-46	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
HHOLBAFO_01938	2.04e-252	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HHOLBAFO_01940	2.05e-239	-	-	-	EGP	-	-	-	Major Facilitator
HHOLBAFO_01941	1.97e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HHOLBAFO_01942	1.62e-58	yodA	-	-	S	-	-	-	Tautomerase enzyme
HHOLBAFO_01943	1.92e-29	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HHOLBAFO_01944	7.71e-148	pnb	-	-	C	-	-	-	nitroreductase
HHOLBAFO_01945	4.73e-32	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
HHOLBAFO_01946	9.32e-108	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HHOLBAFO_01947	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HHOLBAFO_01948	2.42e-133	-	-	-	S	-	-	-	T5orf172
HHOLBAFO_01950	2.11e-23	-	-	-	S	-	-	-	zinc-ribbon domain
HHOLBAFO_01952	8.34e-101	-	-	-	-	-	-	-	-
HHOLBAFO_01953	4.91e-154	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	sugar phosphate isomerase involved in capsule formation
HHOLBAFO_01954	6.1e-145	kdsA	2.5.1.55	-	H	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
HHOLBAFO_01955	3.3e-92	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HHOLBAFO_01956	7.65e-261	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HHOLBAFO_01962	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HHOLBAFO_01972	3.62e-154	-	-	-	L	-	-	-	MULE transposase domain
HHOLBAFO_01973	1.07e-23	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
HHOLBAFO_01974	3.35e-115	-	-	-	P	-	-	-	Cadmium resistance transporter
HHOLBAFO_01975	7.52e-65	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HHOLBAFO_01977	1.77e-73	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein