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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IIAPEOEC_00001	1.37e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IIAPEOEC_00003	1.62e-70	-	-	-	-	-	-	-	-
IIAPEOEC_00004	5.15e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IIAPEOEC_00005	4.11e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIAPEOEC_00006	4.23e-76	-	-	-	-	-	-	-	-
IIAPEOEC_00007	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIAPEOEC_00008	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIAPEOEC_00009	1.14e-105	-	-	-	K	-	-	-	Transcriptional regulator
IIAPEOEC_00010	1.28e-275	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IIAPEOEC_00011	6.85e-258	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IIAPEOEC_00012	2.22e-78	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IIAPEOEC_00013	1.03e-59	yxeL	-	-	K	-	-	-	acetyltransferase
IIAPEOEC_00014	6.91e-98	yxeN	-	-	U	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
IIAPEOEC_00015	2.15e-100	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IIAPEOEC_00016	1.71e-184	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
IIAPEOEC_00017	3.62e-215	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
IIAPEOEC_00018	1.58e-102	-	-	-	S	-	-	-	MmgE/PrpD family
IIAPEOEC_00020	5.39e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
IIAPEOEC_00021	1.32e-146	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
IIAPEOEC_00022	1.19e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00023	2.14e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IIAPEOEC_00025	9.55e-222	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
IIAPEOEC_00026	1.37e-35	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
IIAPEOEC_00027	6.45e-202	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IIAPEOEC_00029	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IIAPEOEC_00030	6.46e-215	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IIAPEOEC_00031	3.47e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
IIAPEOEC_00032	5.07e-189	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
IIAPEOEC_00033	3.91e-244	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IIAPEOEC_00034	1.89e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IIAPEOEC_00035	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IIAPEOEC_00036	1.02e-161	-	-	-	F	-	-	-	glutamine amidotransferase
IIAPEOEC_00037	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IIAPEOEC_00038	1.44e-82	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IIAPEOEC_00039	3.53e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IIAPEOEC_00040	9.35e-101	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIAPEOEC_00041	5.17e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IIAPEOEC_00042	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIAPEOEC_00043	1.25e-198	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IIAPEOEC_00044	3.59e-240	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IIAPEOEC_00045	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IIAPEOEC_00046	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIAPEOEC_00047	2.72e-261	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIAPEOEC_00048	2.54e-120	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IIAPEOEC_00049	2.75e-165	-	-	-	EGP	-	-	-	Major Facilitator
IIAPEOEC_00050	7.03e-216	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIAPEOEC_00051	7.15e-232	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IIAPEOEC_00052	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IIAPEOEC_00053	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IIAPEOEC_00054	7.42e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IIAPEOEC_00055	1.34e-279	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IIAPEOEC_00056	2.87e-219	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIAPEOEC_00057	1.01e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IIAPEOEC_00058	2.3e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIAPEOEC_00059	7.39e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IIAPEOEC_00060	3.38e-293	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
IIAPEOEC_00061	5.64e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
IIAPEOEC_00062	1.38e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IIAPEOEC_00063	1.16e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIAPEOEC_00064	1.15e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IIAPEOEC_00066	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IIAPEOEC_00067	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IIAPEOEC_00068	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IIAPEOEC_00069	4.04e-173	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IIAPEOEC_00070	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIAPEOEC_00071	3.96e-181	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIAPEOEC_00072	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIAPEOEC_00073	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IIAPEOEC_00074	2.89e-112	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIAPEOEC_00076	1.56e-253	-	-	-	S	-	-	-	Helix-turn-helix domain
IIAPEOEC_00077	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IIAPEOEC_00078	2.27e-67	-	-	-	M	-	-	-	Lysin motif
IIAPEOEC_00079	3.8e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IIAPEOEC_00080	1.33e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IIAPEOEC_00081	1.83e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IIAPEOEC_00082	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIAPEOEC_00083	5.68e-297	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IIAPEOEC_00084	1.49e-201	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IIAPEOEC_00085	8.09e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIAPEOEC_00086	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00087	1.78e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIAPEOEC_00088	9.19e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIAPEOEC_00089	1.34e-139	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IIAPEOEC_00090	2.71e-197	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
IIAPEOEC_00091	1.69e-277	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
IIAPEOEC_00092	5.71e-145	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
IIAPEOEC_00093	1.17e-215	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IIAPEOEC_00094	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
IIAPEOEC_00095	4.96e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IIAPEOEC_00096	6.95e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIAPEOEC_00097	5.87e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIAPEOEC_00098	8.52e-211	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IIAPEOEC_00099	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIAPEOEC_00100	1.24e-195	-	-	-	D	-	-	-	DNA integration
IIAPEOEC_00101	8.93e-218	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IIAPEOEC_00102	1.24e-132	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIAPEOEC_00103	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIAPEOEC_00104	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIAPEOEC_00105	2.53e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
IIAPEOEC_00106	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IIAPEOEC_00107	7.86e-92	-	-	-	S	-	-	-	Belongs to the HesB IscA family
IIAPEOEC_00108	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IIAPEOEC_00109	8.29e-08	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IIAPEOEC_00110	3.75e-100	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IIAPEOEC_00111	1.64e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IIAPEOEC_00112	6.88e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
IIAPEOEC_00113	3.75e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
IIAPEOEC_00114	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
IIAPEOEC_00116	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IIAPEOEC_00117	4.66e-100	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IIAPEOEC_00118	4.11e-310	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IIAPEOEC_00120	3.66e-43	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IIAPEOEC_00121	3.57e-56	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IIAPEOEC_00122	3.59e-11	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IIAPEOEC_00123	2.34e-10	odh	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
IIAPEOEC_00124	2.37e-15	odh	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD NADP octopine nopaline dehydrogenase
IIAPEOEC_00125	8.78e-69	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
IIAPEOEC_00126	2.34e-42	odh	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD NADP octopine nopaline dehydrogenase
IIAPEOEC_00127	2.91e-153	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
IIAPEOEC_00128	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
IIAPEOEC_00129	5.43e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IIAPEOEC_00130	3.51e-137	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IIAPEOEC_00131	2.02e-117	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IIAPEOEC_00132	4.94e-76	-	-	-	S	-	-	-	Fic/DOC family
IIAPEOEC_00133	1.98e-40	-	-	-	S	-	-	-	Fic/DOC family
IIAPEOEC_00134	7.89e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
IIAPEOEC_00135	8.33e-311	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
IIAPEOEC_00136	8.71e-139	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
IIAPEOEC_00137	8.25e-271	-	-	-	E	-	-	-	Aminotransferase
IIAPEOEC_00140	1.24e-162	-	-	-	S	-	-	-	Phage minor capsid protein 2
IIAPEOEC_00141	1.49e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IIAPEOEC_00142	7.8e-124	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IIAPEOEC_00144	1.02e-206	-	-	-	S	-	-	-	DUF218 domain
IIAPEOEC_00145	7.7e-212	yvgN	-	-	C	-	-	-	Aldo keto reductase
IIAPEOEC_00146	4.36e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IIAPEOEC_00147	5.86e-190	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IIAPEOEC_00148	2.93e-259	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IIAPEOEC_00149	3.27e-228	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIAPEOEC_00150	1.76e-279	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IIAPEOEC_00151	3.93e-248	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IIAPEOEC_00152	1.45e-157	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
IIAPEOEC_00153	3.1e-129	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
IIAPEOEC_00154	6.34e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00155	6.29e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIAPEOEC_00156	4.71e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
IIAPEOEC_00157	7.28e-101	ywnA	-	-	K	-	-	-	Transcriptional regulator
IIAPEOEC_00158	6.11e-96	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
IIAPEOEC_00159	2.36e-98	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IIAPEOEC_00160	3.85e-30	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
IIAPEOEC_00161	2.82e-08	-	-	-	GM	-	-	-	NmrA-like family
IIAPEOEC_00162	2.63e-58	-	-	-	K	-	-	-	transcriptional regulator
IIAPEOEC_00163	1.54e-138	-	-	-	L	-	-	-	Integrase
IIAPEOEC_00164	3.07e-54	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IIAPEOEC_00165	5.79e-167	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IIAPEOEC_00166	1.49e-48	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
IIAPEOEC_00167	2.62e-08	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
IIAPEOEC_00168	4.88e-282	-	-	-	P	-	-	-	Chloride transporter, ClC family
IIAPEOEC_00169	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIAPEOEC_00170	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIAPEOEC_00171	9.07e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
IIAPEOEC_00172	2.63e-210	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIAPEOEC_00173	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IIAPEOEC_00174	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIAPEOEC_00175	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IIAPEOEC_00176	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIAPEOEC_00177	9.41e-298	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIAPEOEC_00178	2.68e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IIAPEOEC_00179	6.4e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IIAPEOEC_00180	1.93e-220	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
IIAPEOEC_00181	2.09e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIAPEOEC_00182	8.79e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIAPEOEC_00183	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIAPEOEC_00184	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIAPEOEC_00185	7.99e-299	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IIAPEOEC_00186	9.19e-244	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIAPEOEC_00187	1.04e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IIAPEOEC_00188	7.28e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIAPEOEC_00189	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
IIAPEOEC_00190	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
IIAPEOEC_00191	4.68e-298	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IIAPEOEC_00192	3.88e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IIAPEOEC_00193	2.81e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00194	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IIAPEOEC_00195	9.04e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
IIAPEOEC_00196	1.37e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IIAPEOEC_00197	1.56e-231	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IIAPEOEC_00198	4.18e-147	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IIAPEOEC_00199	4.66e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IIAPEOEC_00200	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIAPEOEC_00201	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IIAPEOEC_00203	4.68e-27	-	-	-	S	-	-	-	zinc-ribbon domain
IIAPEOEC_00204	1.13e-52	-	-	-	-	-	-	-	-
IIAPEOEC_00205	2.39e-12	-	-	-	M	-	-	-	LysM domain
IIAPEOEC_00206	1.11e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IIAPEOEC_00207	1.87e-276	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
IIAPEOEC_00208	1.67e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIAPEOEC_00209	6.81e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IIAPEOEC_00210	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIAPEOEC_00211	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIAPEOEC_00213	8.27e-188	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIAPEOEC_00214	2.3e-173	-	-	-	S	-	-	-	Membrane
IIAPEOEC_00215	1.52e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
IIAPEOEC_00216	2.31e-110	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IIAPEOEC_00217	5.06e-298	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IIAPEOEC_00219	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
IIAPEOEC_00220	3.84e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIAPEOEC_00221	2.19e-270	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IIAPEOEC_00222	5.45e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
IIAPEOEC_00224	9.85e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IIAPEOEC_00225	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IIAPEOEC_00226	5.45e-233	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IIAPEOEC_00227	5.65e-277	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
IIAPEOEC_00228	3.29e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IIAPEOEC_00229	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IIAPEOEC_00230	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIAPEOEC_00231	7.25e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIAPEOEC_00232	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIAPEOEC_00233	1.18e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIAPEOEC_00234	1.25e-76	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IIAPEOEC_00235	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIAPEOEC_00236	9.39e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IIAPEOEC_00237	1.1e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IIAPEOEC_00238	7.81e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IIAPEOEC_00239	9.94e-253	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IIAPEOEC_00240	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIAPEOEC_00241	2.58e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIAPEOEC_00242	4.59e-248	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIAPEOEC_00243	1.77e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIAPEOEC_00244	4.39e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIAPEOEC_00245	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IIAPEOEC_00246	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
IIAPEOEC_00247	7.49e-181	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
IIAPEOEC_00248	2.31e-63	-	-	-	-	-	-	-	-
IIAPEOEC_00249	2.11e-200	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIAPEOEC_00250	9.07e-146	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIAPEOEC_00251	1.26e-243	ampC	-	-	V	-	-	-	Beta-lactamase
IIAPEOEC_00252	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IIAPEOEC_00253	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00254	1.02e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
IIAPEOEC_00255	3.24e-10	-	-	-	-	-	-	-	-
IIAPEOEC_00257	1.55e-74	-	-	-	-	-	-	-	-
IIAPEOEC_00259	2.13e-167	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
IIAPEOEC_00260	4.49e-185	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIAPEOEC_00261	7.54e-205	yvgN	-	-	S	-	-	-	Aldo keto reductase
IIAPEOEC_00262	7.9e-153	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IIAPEOEC_00263	3.38e-109	-	-	-	K	-	-	-	GNAT family
IIAPEOEC_00266	3.55e-123	-	-	-	-	-	-	-	-
IIAPEOEC_00267	4.06e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
IIAPEOEC_00268	1.44e-228	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIAPEOEC_00270	2.12e-145	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
IIAPEOEC_00273	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
IIAPEOEC_00275	5.87e-239	-	-	-	EGP	-	-	-	Major Facilitator
IIAPEOEC_00277	6.02e-68	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IIAPEOEC_00278	2.49e-73	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IIAPEOEC_00279	2.31e-56	-	-	-	S	-	-	-	Protein conserved in bacteria
IIAPEOEC_00280	2.6e-124	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
IIAPEOEC_00281	1.24e-57	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IIAPEOEC_00282	6.41e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
IIAPEOEC_00283	4.53e-238	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAPEOEC_00284	4.9e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
IIAPEOEC_00285	9.84e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIAPEOEC_00286	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IIAPEOEC_00287	4.34e-198	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIAPEOEC_00288	8.64e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIAPEOEC_00289	1.91e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIAPEOEC_00290	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIAPEOEC_00291	1.89e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00293	5.48e-70	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
IIAPEOEC_00294	4.39e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IIAPEOEC_00295	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIAPEOEC_00296	5.82e-277	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIAPEOEC_00297	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIAPEOEC_00298	9.05e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
IIAPEOEC_00299	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIAPEOEC_00300	1.17e-269	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIAPEOEC_00301	2.23e-11	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIAPEOEC_00302	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIAPEOEC_00303	3.39e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IIAPEOEC_00304	1.63e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IIAPEOEC_00305	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IIAPEOEC_00306	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IIAPEOEC_00307	1.34e-122	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IIAPEOEC_00308	4.62e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IIAPEOEC_00309	5.91e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIAPEOEC_00310	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IIAPEOEC_00311	1.08e-62	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
IIAPEOEC_00312	1.04e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IIAPEOEC_00313	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IIAPEOEC_00314	1.96e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IIAPEOEC_00315	2.57e-64	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IIAPEOEC_00316	4.97e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIAPEOEC_00317	2.14e-123	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
IIAPEOEC_00318	9.96e-212	-	-	-	L	-	-	-	PFAM Integrase catalytic region
IIAPEOEC_00319	8.69e-98	-	-	-	-	-	-	-	-
IIAPEOEC_00320	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IIAPEOEC_00321	9.87e-238	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
IIAPEOEC_00322	2.39e-98	-	-	-	P	-	-	-	ArsC family
IIAPEOEC_00323	3.13e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIAPEOEC_00324	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIAPEOEC_00325	2.69e-158	-	-	-	S	-	-	-	repeat protein
IIAPEOEC_00326	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
IIAPEOEC_00327	3.62e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IIAPEOEC_00328	0.0	-	-	-	S	-	-	-	amidohydrolase
IIAPEOEC_00329	1.39e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIAPEOEC_00330	2.64e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IIAPEOEC_00331	3.8e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIAPEOEC_00332	2.68e-08	-	-	-	-	-	-	-	-
IIAPEOEC_00333	2.12e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IIAPEOEC_00334	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IIAPEOEC_00335	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIAPEOEC_00337	3.58e-142	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
IIAPEOEC_00338	4.13e-185	ylmH	-	-	S	-	-	-	S4 domain protein
IIAPEOEC_00339	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IIAPEOEC_00340	1.5e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IIAPEOEC_00341	4.99e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIAPEOEC_00342	7.72e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIAPEOEC_00343	7.09e-189	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIAPEOEC_00344	8.4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIAPEOEC_00345	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIAPEOEC_00346	5.43e-228	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIAPEOEC_00347	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IIAPEOEC_00348	1.06e-30	ftsL	-	-	D	-	-	-	Cell division protein FtsL
IIAPEOEC_00349	8.91e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIAPEOEC_00350	3.12e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IIAPEOEC_00351	9.82e-76	-	-	-	-	-	-	-	-
IIAPEOEC_00352	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IIAPEOEC_00353	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IIAPEOEC_00354	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIAPEOEC_00355	5.1e-204	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
IIAPEOEC_00356	5.17e-249	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IIAPEOEC_00357	3.12e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIAPEOEC_00358	7.8e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIAPEOEC_00359	3.03e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IIAPEOEC_00360	1.58e-145	yjbH	-	-	Q	-	-	-	Thioredoxin
IIAPEOEC_00361	9.03e-258	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IIAPEOEC_00362	2.07e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IIAPEOEC_00363	6.49e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIAPEOEC_00384	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IIAPEOEC_00385	5.26e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IIAPEOEC_00386	1.31e-209	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIAPEOEC_00387	5.87e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIAPEOEC_00388	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IIAPEOEC_00389	2.31e-69	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
IIAPEOEC_00390	2.5e-258	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIAPEOEC_00391	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIAPEOEC_00392	4.45e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIAPEOEC_00393	8.42e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IIAPEOEC_00394	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IIAPEOEC_00395	9.05e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IIAPEOEC_00396	4.12e-50	-	-	-	-	-	-	-	-
IIAPEOEC_00397	0.0	ydaO	-	-	E	-	-	-	amino acid
IIAPEOEC_00398	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIAPEOEC_00399	1.15e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIAPEOEC_00400	1.56e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIAPEOEC_00401	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IIAPEOEC_00402	4.74e-221	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIAPEOEC_00403	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IIAPEOEC_00404	3.12e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IIAPEOEC_00405	1.1e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IIAPEOEC_00406	6.46e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIAPEOEC_00407	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IIAPEOEC_00408	6.55e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIAPEOEC_00409	5.52e-91	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIAPEOEC_00410	3.12e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIAPEOEC_00411	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IIAPEOEC_00412	8.84e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IIAPEOEC_00413	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIAPEOEC_00414	4.39e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIAPEOEC_00415	4.1e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IIAPEOEC_00416	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIAPEOEC_00418	2.87e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIAPEOEC_00419	3.75e-141	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IIAPEOEC_00420	6.55e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IIAPEOEC_00421	2.1e-270	arcT	-	-	E	-	-	-	Aminotransferase
IIAPEOEC_00422	1.67e-272	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IIAPEOEC_00423	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IIAPEOEC_00424	2.33e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
IIAPEOEC_00425	4.08e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
IIAPEOEC_00426	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIAPEOEC_00427	2.51e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
IIAPEOEC_00428	1.17e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IIAPEOEC_00429	1.31e-218	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIAPEOEC_00430	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IIAPEOEC_00431	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIAPEOEC_00432	4.7e-188	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IIAPEOEC_00433	2.83e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIAPEOEC_00434	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IIAPEOEC_00435	6.77e-247	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IIAPEOEC_00436	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IIAPEOEC_00437	2.59e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIAPEOEC_00438	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IIAPEOEC_00439	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIAPEOEC_00440	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIAPEOEC_00441	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIAPEOEC_00443	6.57e-107	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIAPEOEC_00444	5.41e-47	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IIAPEOEC_00445	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIAPEOEC_00446	1.48e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIAPEOEC_00447	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IIAPEOEC_00448	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IIAPEOEC_00449	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IIAPEOEC_00450	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IIAPEOEC_00451	7.75e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
IIAPEOEC_00452	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IIAPEOEC_00453	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIAPEOEC_00454	6.43e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIAPEOEC_00455	1.82e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IIAPEOEC_00456	1.96e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIAPEOEC_00457	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIAPEOEC_00458	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IIAPEOEC_00459	1.01e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IIAPEOEC_00460	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IIAPEOEC_00461	1.87e-133	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IIAPEOEC_00462	1.19e-171	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IIAPEOEC_00463	5.96e-264	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IIAPEOEC_00464	3.68e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIAPEOEC_00465	6.42e-154	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
IIAPEOEC_00466	1.45e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
IIAPEOEC_00467	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IIAPEOEC_00468	1.93e-204	-	-	-	EG	-	-	-	EamA-like transporter family
IIAPEOEC_00469	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IIAPEOEC_00470	1.05e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
IIAPEOEC_00471	2.8e-135	-	-	-	K	-	-	-	acetyltransferase
IIAPEOEC_00472	4.62e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IIAPEOEC_00473	5.92e-164	sptS	-	-	T	-	-	-	Histidine kinase
IIAPEOEC_00474	1.16e-101	dltr	-	-	K	-	-	-	response regulator
IIAPEOEC_00475	7.85e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
IIAPEOEC_00476	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IIAPEOEC_00477	0.0	-	1.7.2.5	-	P	ko:K04561	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Cytochrome C and Quinol oxidase polypeptide I
IIAPEOEC_00479	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IIAPEOEC_00481	3.13e-154	-	-	-	-	-	-	-	-
IIAPEOEC_00482	2.28e-133	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IIAPEOEC_00483	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
IIAPEOEC_00484	4.42e-221	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
IIAPEOEC_00485	1.1e-07	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
IIAPEOEC_00487	8.67e-114	-	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IIAPEOEC_00488	4.61e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIAPEOEC_00489	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00490	1.19e-72	-	-	-	S	-	-	-	FMN_bind
IIAPEOEC_00491	1.19e-81	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIAPEOEC_00492	1.01e-164	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
IIAPEOEC_00493	5.66e-71	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
IIAPEOEC_00494	1.92e-60	cpg2	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
IIAPEOEC_00495	8.83e-99	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIAPEOEC_00496	1.09e-62	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIAPEOEC_00497	2.29e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IIAPEOEC_00498	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IIAPEOEC_00499	4.1e-48	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IIAPEOEC_00500	3.44e-198	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IIAPEOEC_00501	6.25e-78	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IIAPEOEC_00502	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
IIAPEOEC_00503	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIAPEOEC_00505	9.15e-194	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IIAPEOEC_00506	3.77e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIAPEOEC_00507	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
IIAPEOEC_00508	7.77e-261	-	-	-	EGP	-	-	-	Major Facilitator
IIAPEOEC_00509	4.45e-274	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
IIAPEOEC_00510	2.38e-171	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
IIAPEOEC_00511	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IIAPEOEC_00512	1.59e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIAPEOEC_00513	3.58e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
IIAPEOEC_00514	1.8e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
IIAPEOEC_00515	1.04e-17	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIAPEOEC_00516	2.94e-54	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIAPEOEC_00517	1.46e-106	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IIAPEOEC_00518	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
IIAPEOEC_00519	2.95e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IIAPEOEC_00520	2.95e-133	-	-	-	NU	-	-	-	mannosyl-glycoprotein
IIAPEOEC_00521	1.28e-237	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IIAPEOEC_00522	1.33e-46	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IIAPEOEC_00523	1.71e-104	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IIAPEOEC_00524	2.51e-40	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IIAPEOEC_00525	4.46e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
IIAPEOEC_00526	2.2e-151	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IIAPEOEC_00527	2.93e-135	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIAPEOEC_00528	4.89e-201	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IIAPEOEC_00529	1.85e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIAPEOEC_00531	6.37e-48	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
IIAPEOEC_00532	3.43e-88	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
IIAPEOEC_00533	5.37e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IIAPEOEC_00534	4.15e-145	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IIAPEOEC_00535	4.28e-182	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IIAPEOEC_00536	7.4e-181	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IIAPEOEC_00537	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIAPEOEC_00538	4.25e-236	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIAPEOEC_00539	3.58e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
IIAPEOEC_00540	2.34e-141	-	-	-	-	-	-	-	-
IIAPEOEC_00541	1.06e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IIAPEOEC_00542	2.89e-152	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IIAPEOEC_00543	2.44e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IIAPEOEC_00544	4.35e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IIAPEOEC_00545	3.23e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
IIAPEOEC_00546	1.2e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IIAPEOEC_00547	7.57e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
IIAPEOEC_00548	3.48e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
IIAPEOEC_00550	2.68e-50	-	-	-	-	-	-	-	-
IIAPEOEC_00552	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IIAPEOEC_00553	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IIAPEOEC_00554	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IIAPEOEC_00555	3.39e-226	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IIAPEOEC_00556	2.22e-190	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IIAPEOEC_00558	1.23e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
IIAPEOEC_00559	8.67e-170	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00560	5.8e-270	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IIAPEOEC_00561	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIAPEOEC_00562	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
IIAPEOEC_00563	8.85e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
IIAPEOEC_00564	3.73e-151	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIAPEOEC_00565	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IIAPEOEC_00566	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IIAPEOEC_00567	3.67e-175	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
IIAPEOEC_00568	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIAPEOEC_00569	7.57e-208	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIAPEOEC_00570	2.8e-135	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIAPEOEC_00571	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIAPEOEC_00572	3.15e-311	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
IIAPEOEC_00573	3.11e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IIAPEOEC_00574	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIAPEOEC_00575	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IIAPEOEC_00576	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIAPEOEC_00577	5.12e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IIAPEOEC_00578	1.55e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IIAPEOEC_00579	4.65e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IIAPEOEC_00580	6.3e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IIAPEOEC_00581	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IIAPEOEC_00582	6.58e-120	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIAPEOEC_00583	2.63e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IIAPEOEC_00584	1.62e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIAPEOEC_00585	1.67e-171	yqeM	-	-	Q	-	-	-	Methyltransferase
IIAPEOEC_00586	2.18e-269	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IIAPEOEC_00587	9.71e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IIAPEOEC_00588	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IIAPEOEC_00589	5.62e-155	csrR	-	-	K	-	-	-	response regulator
IIAPEOEC_00590	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIAPEOEC_00591	1.8e-296	-	-	-	V	-	-	-	MatE
IIAPEOEC_00592	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IIAPEOEC_00593	9.66e-198	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIAPEOEC_00594	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IIAPEOEC_00595	5.66e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIAPEOEC_00596	4.08e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IIAPEOEC_00597	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIAPEOEC_00598	2.58e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIAPEOEC_00599	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIAPEOEC_00600	2.93e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IIAPEOEC_00601	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIAPEOEC_00602	0.0	-	-	-	S	-	-	-	membrane
IIAPEOEC_00603	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IIAPEOEC_00604	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IIAPEOEC_00605	4.27e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIAPEOEC_00606	1.21e-134	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
IIAPEOEC_00607	4.99e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IIAPEOEC_00608	8.69e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IIAPEOEC_00609	1.7e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IIAPEOEC_00610	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IIAPEOEC_00611	5.79e-217	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIAPEOEC_00612	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IIAPEOEC_00613	4.76e-19	-	-	-	-	-	-	-	-
IIAPEOEC_00614	1.1e-200	-	-	-	-	-	-	-	-
IIAPEOEC_00615	1.58e-224	-	-	-	-	-	-	-	-
IIAPEOEC_00616	6.11e-118	-	-	-	S	-	-	-	Protein conserved in bacteria
IIAPEOEC_00617	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IIAPEOEC_00618	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
IIAPEOEC_00619	1.97e-129	-	-	-	-	-	-	-	-
IIAPEOEC_00620	7.11e-172	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IIAPEOEC_00621	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IIAPEOEC_00622	2.06e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
IIAPEOEC_00623	9.48e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIAPEOEC_00624	9.46e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IIAPEOEC_00625	1.77e-298	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IIAPEOEC_00626	3.09e-25	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IIAPEOEC_00627	1.86e-262	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IIAPEOEC_00628	2.99e-57	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
IIAPEOEC_00629	5.16e-57	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
IIAPEOEC_00630	2.45e-41	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
IIAPEOEC_00631	4.69e-230	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IIAPEOEC_00632	2.59e-229	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
IIAPEOEC_00633	2.74e-272	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIAPEOEC_00634	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IIAPEOEC_00635	9.63e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IIAPEOEC_00636	3.23e-270	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IIAPEOEC_00637	1.07e-129	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
IIAPEOEC_00638	3.63e-271	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
IIAPEOEC_00639	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IIAPEOEC_00640	1.48e-270	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IIAPEOEC_00641	7.61e-203	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
IIAPEOEC_00642	7.37e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IIAPEOEC_00643	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIAPEOEC_00644	1.52e-300	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIAPEOEC_00645	1.05e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIAPEOEC_00646	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIAPEOEC_00647	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IIAPEOEC_00648	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IIAPEOEC_00649	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IIAPEOEC_00651	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IIAPEOEC_00652	3.96e-28	-	-	-	-	-	-	-	-
IIAPEOEC_00653	9.13e-17	-	-	-	-	-	-	-	-
IIAPEOEC_00654	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IIAPEOEC_00656	7.61e-299	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
IIAPEOEC_00657	3.44e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
IIAPEOEC_00658	6.38e-118	-	-	-	GM	-	-	-	NAD(P)H-binding
IIAPEOEC_00659	7.06e-58	-	-	-	GM	-	-	-	NAD(P)H-binding
IIAPEOEC_00660	2.24e-196	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IIAPEOEC_00662	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IIAPEOEC_00664	3.49e-133	-	-	-	G	-	-	-	Major Facilitator Superfamily
IIAPEOEC_00665	3.55e-64	-	-	-	G	-	-	-	Major Facilitator Superfamily
IIAPEOEC_00666	7.56e-15	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
IIAPEOEC_00667	8.14e-162	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IIAPEOEC_00668	3.39e-84	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IIAPEOEC_00669	4.48e-131	-	-	-	-	-	-	-	-
IIAPEOEC_00670	4.17e-96	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IIAPEOEC_00671	8.24e-153	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IIAPEOEC_00672	2.65e-247	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IIAPEOEC_00673	2.06e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IIAPEOEC_00674	7.13e-276	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
IIAPEOEC_00675	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAPEOEC_00676	1.49e-225	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IIAPEOEC_00677	3.15e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IIAPEOEC_00678	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
IIAPEOEC_00679	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IIAPEOEC_00680	2e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
IIAPEOEC_00681	9.38e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IIAPEOEC_00682	1.46e-300	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IIAPEOEC_00683	2.14e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IIAPEOEC_00684	1.76e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IIAPEOEC_00685	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IIAPEOEC_00686	7.31e-163	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IIAPEOEC_00687	2.3e-50	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IIAPEOEC_00688	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IIAPEOEC_00689	2.03e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIAPEOEC_00690	1.39e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIAPEOEC_00691	9.61e-106	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IIAPEOEC_00692	1.15e-229	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IIAPEOEC_00693	1.5e-85	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IIAPEOEC_00694	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
IIAPEOEC_00695	1.26e-210	-	-	-	C	-	-	-	Aldo keto reductase
IIAPEOEC_00696	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IIAPEOEC_00697	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IIAPEOEC_00698	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIAPEOEC_00699	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
IIAPEOEC_00700	4.71e-47	-	-	-	-	-	-	-	-
IIAPEOEC_00701	8.98e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIAPEOEC_00702	3.13e-228	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAPEOEC_00703	3.77e-176	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
IIAPEOEC_00704	2.3e-26	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
IIAPEOEC_00705	1.72e-243	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIAPEOEC_00706	4.06e-140	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
IIAPEOEC_00707	7.69e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
IIAPEOEC_00708	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IIAPEOEC_00709	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IIAPEOEC_00710	2.29e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIAPEOEC_00711	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
IIAPEOEC_00712	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIAPEOEC_00713	1.92e-269	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IIAPEOEC_00714	4.51e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IIAPEOEC_00715	9.32e-182	yycI	-	-	S	-	-	-	YycH protein
IIAPEOEC_00716	1.16e-302	yycH	-	-	S	-	-	-	YycH protein
IIAPEOEC_00717	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIAPEOEC_00718	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IIAPEOEC_00721	3.97e-64	-	-	-	-	-	-	-	-
IIAPEOEC_00722	1.26e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
IIAPEOEC_00723	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IIAPEOEC_00724	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IIAPEOEC_00725	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IIAPEOEC_00726	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIAPEOEC_00727	1.7e-151	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIAPEOEC_00728	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IIAPEOEC_00729	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIAPEOEC_00730	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIAPEOEC_00731	9.75e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIAPEOEC_00732	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IIAPEOEC_00733	1.52e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIAPEOEC_00734	3.8e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIAPEOEC_00735	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IIAPEOEC_00736	5.32e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIAPEOEC_00737	1.43e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIAPEOEC_00738	4.39e-189	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
IIAPEOEC_00739	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIAPEOEC_00740	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIAPEOEC_00741	2.23e-73	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
IIAPEOEC_00742	1.2e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IIAPEOEC_00743	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IIAPEOEC_00744	3.96e-274	-	-	-	G	-	-	-	Transporter, major facilitator family protein
IIAPEOEC_00745	4.39e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IIAPEOEC_00746	5.78e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IIAPEOEC_00747	2.34e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IIAPEOEC_00748	8.61e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IIAPEOEC_00749	7.63e-230	-	-	-	K	-	-	-	WYL domain
IIAPEOEC_00750	3.96e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
IIAPEOEC_00751	3.18e-46	-	-	-	-	-	-	-	-
IIAPEOEC_00754	5.35e-84	-	-	-	-	-	-	-	-
IIAPEOEC_00755	1.36e-142	yicL	-	-	EG	-	-	-	EamA-like transporter family
IIAPEOEC_00756	1.45e-107	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
IIAPEOEC_00757	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IIAPEOEC_00758	5.05e-210	-	-	-	K	-	-	-	LysR substrate binding domain
IIAPEOEC_00759	9.52e-205	rssA	-	-	S	-	-	-	Phospholipase, patatin family
IIAPEOEC_00760	6.03e-270	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IIAPEOEC_00761	5.79e-233	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
IIAPEOEC_00762	2.06e-30	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IIAPEOEC_00763	4.77e-116	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
IIAPEOEC_00764	2.09e-243	flp	-	-	V	-	-	-	Beta-lactamase
IIAPEOEC_00765	1.87e-289	-	-	-	-	-	-	-	-
IIAPEOEC_00767	1.7e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIAPEOEC_00768	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIAPEOEC_00769	1.85e-207	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
IIAPEOEC_00770	8.78e-206	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IIAPEOEC_00771	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIAPEOEC_00773	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IIAPEOEC_00775	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IIAPEOEC_00776	5.91e-299	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IIAPEOEC_00778	5.21e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
IIAPEOEC_00779	6.9e-126	-	-	-	K	-	-	-	Virulence activator alpha C-term
IIAPEOEC_00780	1.54e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IIAPEOEC_00782	8.99e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IIAPEOEC_00784	7.33e-184	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IIAPEOEC_00785	8.82e-51	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIAPEOEC_00786	8.47e-67	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIAPEOEC_00787	1.22e-32	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIAPEOEC_00788	1.65e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
IIAPEOEC_00790	7.48e-301	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
IIAPEOEC_00791	8.67e-44	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
IIAPEOEC_00792	3.57e-117	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
IIAPEOEC_00793	7.97e-41	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IIAPEOEC_00794	2.8e-96	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
IIAPEOEC_00795	1.99e-95	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IIAPEOEC_00796	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IIAPEOEC_00797	3.26e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IIAPEOEC_00798	1.29e-196	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IIAPEOEC_00799	7.42e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IIAPEOEC_00800	0.0	-	-	-	L	-	-	-	DNA helicase
IIAPEOEC_00801	7.63e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIAPEOEC_00802	3.57e-282	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IIAPEOEC_00803	5.3e-239	-	-	-	-	-	-	-	-
IIAPEOEC_00804	8.66e-161	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
IIAPEOEC_00805	2.27e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
IIAPEOEC_00806	1.36e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
IIAPEOEC_00807	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIAPEOEC_00808	7.76e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IIAPEOEC_00809	3.77e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIAPEOEC_00810	8.42e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIAPEOEC_00811	9.13e-202	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IIAPEOEC_00812	7.82e-210	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IIAPEOEC_00813	1.29e-119	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IIAPEOEC_00814	2.31e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
IIAPEOEC_00815	6.12e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IIAPEOEC_00816	2.72e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIAPEOEC_00817	1.73e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIAPEOEC_00818	2.88e-75	-	-	-	-	-	-	-	-
IIAPEOEC_00819	1.37e-182	yidA	-	-	S	-	-	-	hydrolase
IIAPEOEC_00820	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
IIAPEOEC_00821	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IIAPEOEC_00822	7.45e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIAPEOEC_00823	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIAPEOEC_00824	5.09e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIAPEOEC_00825	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IIAPEOEC_00826	4.56e-62	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
IIAPEOEC_00827	3.63e-83	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
IIAPEOEC_00828	3.63e-156	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IIAPEOEC_00829	7.41e-61	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIAPEOEC_00830	9.6e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IIAPEOEC_00831	3.15e-201	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IIAPEOEC_00832	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIAPEOEC_00833	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIAPEOEC_00834	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIAPEOEC_00835	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIAPEOEC_00836	5.83e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IIAPEOEC_00837	4.51e-148	-	-	-	S	-	-	-	(CBS) domain
IIAPEOEC_00838	3.8e-130	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIAPEOEC_00839	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIAPEOEC_00840	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
IIAPEOEC_00841	1.19e-73	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IIAPEOEC_00842	4.54e-111	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
IIAPEOEC_00843	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIAPEOEC_00844	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IIAPEOEC_00845	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIAPEOEC_00846	1.52e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIAPEOEC_00847	1.07e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIAPEOEC_00848	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IIAPEOEC_00849	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IIAPEOEC_00850	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IIAPEOEC_00851	8.51e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIAPEOEC_00852	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAPEOEC_00853	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAPEOEC_00854	2.4e-172	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IIAPEOEC_00855	6.09e-275	-	-	-	-	-	-	-	-
IIAPEOEC_00856	1.77e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
IIAPEOEC_00857	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIAPEOEC_00858	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIAPEOEC_00859	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIAPEOEC_00860	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IIAPEOEC_00861	3.41e-152	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIAPEOEC_00862	3.16e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IIAPEOEC_00863	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIAPEOEC_00864	1.35e-202	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIAPEOEC_00865	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIAPEOEC_00866	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIAPEOEC_00867	2.49e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIAPEOEC_00868	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIAPEOEC_00869	1.11e-37	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IIAPEOEC_00870	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIAPEOEC_00871	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIAPEOEC_00872	1.5e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIAPEOEC_00873	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIAPEOEC_00874	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIAPEOEC_00875	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIAPEOEC_00876	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIAPEOEC_00877	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIAPEOEC_00878	2.08e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIAPEOEC_00879	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IIAPEOEC_00880	4.09e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IIAPEOEC_00881	1.84e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIAPEOEC_00882	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIAPEOEC_00883	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIAPEOEC_00884	2.6e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IIAPEOEC_00885	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIAPEOEC_00886	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIAPEOEC_00887	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAPEOEC_00888	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IIAPEOEC_00889	2.39e-190	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAPEOEC_00890	2.06e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAPEOEC_00891	2.37e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAPEOEC_00892	2.6e-184	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIAPEOEC_00893	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIAPEOEC_00894	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IIAPEOEC_00895	1.1e-258	-	-	-	S	-	-	-	interspecies interaction between organisms
IIAPEOEC_00896	4.28e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
IIAPEOEC_00897	9.5e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IIAPEOEC_00898	3.74e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIAPEOEC_00899	4.32e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IIAPEOEC_00900	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IIAPEOEC_00901	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIAPEOEC_00902	6.46e-232	camS	-	-	S	-	-	-	sex pheromone
IIAPEOEC_00903	4.92e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIAPEOEC_00904	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIAPEOEC_00905	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIAPEOEC_00906	2.52e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IIAPEOEC_00907	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIAPEOEC_00908	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIAPEOEC_00909	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
IIAPEOEC_00910	1.29e-181	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IIAPEOEC_00911	3.07e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIAPEOEC_00912	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IIAPEOEC_00913	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IIAPEOEC_00914	1.32e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IIAPEOEC_00915	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIAPEOEC_00916	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IIAPEOEC_00917	4.79e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IIAPEOEC_00918	3.3e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IIAPEOEC_00919	1.24e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
IIAPEOEC_00920	5.46e-135	-	-	-	-	-	-	-	-
IIAPEOEC_00922	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIAPEOEC_00923	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIAPEOEC_00924	3.22e-254	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIAPEOEC_00925	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IIAPEOEC_00926	5.67e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIAPEOEC_00927	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIAPEOEC_00928	1.04e-213	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIAPEOEC_00929	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIAPEOEC_00930	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IIAPEOEC_00931	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIAPEOEC_00932	1e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IIAPEOEC_00933	9.12e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IIAPEOEC_00934	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IIAPEOEC_00935	5.11e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIAPEOEC_00936	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IIAPEOEC_00937	7.64e-166	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IIAPEOEC_00938	1.29e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIAPEOEC_00939	7.64e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIAPEOEC_00940	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIAPEOEC_00941	1.7e-281	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIAPEOEC_00942	1.9e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IIAPEOEC_00943	8.46e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IIAPEOEC_00945	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IIAPEOEC_00946	5.75e-98	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IIAPEOEC_00947	1.14e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IIAPEOEC_00948	2.81e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IIAPEOEC_00949	3.3e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIAPEOEC_00950	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIAPEOEC_00951	2e-206	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIAPEOEC_00952	8.07e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIAPEOEC_00953	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IIAPEOEC_00954	1.7e-262	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IIAPEOEC_00955	4.44e-134	-	-	-	-	-	-	-	-
IIAPEOEC_00956	9.3e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIAPEOEC_00957	1.76e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IIAPEOEC_00958	3.05e-73	-	-	-	-	-	-	-	-
IIAPEOEC_00959	5.24e-158	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
IIAPEOEC_00961	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IIAPEOEC_00962	8.13e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IIAPEOEC_00963	3.7e-259	-	-	-	S	-	-	-	associated with various cellular activities
IIAPEOEC_00964	4.63e-266	-	-	-	S	-	-	-	Putative metallopeptidase domain
IIAPEOEC_00965	5.76e-59	-	-	-	-	-	-	-	-
IIAPEOEC_00966	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IIAPEOEC_00967	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IIAPEOEC_00968	1.16e-118	ymdB	-	-	S	-	-	-	Macro domain protein
IIAPEOEC_00969	1.02e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IIAPEOEC_00970	9.63e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIAPEOEC_00971	4.73e-214	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAPEOEC_00972	9.08e-71	-	-	-	-	-	-	-	-
IIAPEOEC_00973	8.93e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IIAPEOEC_00974	1.01e-153	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IIAPEOEC_00975	3.97e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_00976	1.21e-48	-	-	-	-	-	-	-	-
IIAPEOEC_00977	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IIAPEOEC_00978	6.55e-183	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IIAPEOEC_00979	7.74e-231	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IIAPEOEC_00980	1.71e-284	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIAPEOEC_00981	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IIAPEOEC_00982	2.49e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IIAPEOEC_00983	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IIAPEOEC_00984	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IIAPEOEC_00985	6.15e-161	-	-	-	S	-	-	-	Membrane
IIAPEOEC_00986	1.29e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIAPEOEC_00987	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IIAPEOEC_00988	2.45e-222	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IIAPEOEC_00989	9.33e-91	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIAPEOEC_00990	5.95e-23	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIAPEOEC_00991	6.2e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
IIAPEOEC_00992	6.11e-106	usp5	-	-	T	-	-	-	universal stress protein
IIAPEOEC_00993	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IIAPEOEC_00994	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IIAPEOEC_00995	2.08e-265	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
IIAPEOEC_00996	1.81e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
IIAPEOEC_00997	4.33e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IIAPEOEC_00998	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IIAPEOEC_00999	2.79e-115	-	-	-	GM	-	-	-	epimerase
IIAPEOEC_01000	6.93e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IIAPEOEC_01001	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IIAPEOEC_01002	1.5e-254	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IIAPEOEC_01003	6.57e-244	arcT	-	-	E	-	-	-	Dipeptidase
IIAPEOEC_01004	4.48e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IIAPEOEC_01005	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
IIAPEOEC_01006	8.65e-271	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
IIAPEOEC_01007	0.0	fusA1	-	-	J	-	-	-	elongation factor G
IIAPEOEC_01008	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIAPEOEC_01009	2.18e-144	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IIAPEOEC_01010	5.72e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIAPEOEC_01011	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IIAPEOEC_01012	2.7e-204	-	-	-	EG	-	-	-	EamA-like transporter family
IIAPEOEC_01013	7.83e-242	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
IIAPEOEC_01014	5.43e-190	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IIAPEOEC_01015	2.4e-172	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IIAPEOEC_01016	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IIAPEOEC_01017	1.91e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IIAPEOEC_01018	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IIAPEOEC_01019	5.33e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IIAPEOEC_01020	8.67e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IIAPEOEC_01021	9.62e-270	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IIAPEOEC_01022	6.91e-259	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIAPEOEC_01023	7.88e-119	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IIAPEOEC_01024	2e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IIAPEOEC_01025	1.65e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IIAPEOEC_01026	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IIAPEOEC_01027	7.22e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IIAPEOEC_01028	1.08e-112	-	-	-	K	-	-	-	FR47-like protein
IIAPEOEC_01029	5.02e-44	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IIAPEOEC_01030	4.67e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF998)
IIAPEOEC_01031	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
IIAPEOEC_01033	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
IIAPEOEC_01034	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IIAPEOEC_01035	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIAPEOEC_01036	3.51e-183	yceF	-	-	P	ko:K05794	-	ko00000	membrane
IIAPEOEC_01037	1.53e-210	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IIAPEOEC_01038	1.26e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IIAPEOEC_01039	7.52e-300	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IIAPEOEC_01040	3.25e-191	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
IIAPEOEC_01041	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
IIAPEOEC_01042	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IIAPEOEC_01043	1.51e-40	-	-	-	-	-	-	-	-
IIAPEOEC_01044	7.69e-142	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
IIAPEOEC_01045	2.3e-129	dpsB	-	-	P	-	-	-	Belongs to the Dps family
IIAPEOEC_01046	3.19e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
IIAPEOEC_01047	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IIAPEOEC_01048	1.24e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IIAPEOEC_01049	2.8e-230	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
IIAPEOEC_01050	1.12e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IIAPEOEC_01051	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_01052	1.44e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IIAPEOEC_01053	3.57e-22	-	-	-	-	-	-	-	-
IIAPEOEC_01054	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IIAPEOEC_01055	4.46e-238	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
IIAPEOEC_01056	9.46e-96	-	-	-	O	-	-	-	OsmC-like protein
IIAPEOEC_01057	9.06e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IIAPEOEC_01058	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
IIAPEOEC_01059	1.84e-201	-	-	-	-	-	-	-	-
IIAPEOEC_01060	4.83e-10	-	-	-	-	-	-	-	-
IIAPEOEC_01061	3.62e-77	-	-	-	-	-	-	-	-
IIAPEOEC_01062	7.24e-97	uspA3	-	-	T	-	-	-	universal stress protein
IIAPEOEC_01064	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
IIAPEOEC_01065	2.72e-314	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
IIAPEOEC_01066	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIAPEOEC_01067	8.01e-174	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
IIAPEOEC_01068	9.05e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IIAPEOEC_01069	4.84e-157	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IIAPEOEC_01070	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIAPEOEC_01071	3.38e-146	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
IIAPEOEC_01073	7.33e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
IIAPEOEC_01074	3.23e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IIAPEOEC_01075	1.95e-163	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IIAPEOEC_01076	2.22e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IIAPEOEC_01077	3.38e-137	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IIAPEOEC_01078	2.9e-63	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IIAPEOEC_01079	1.46e-115	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IIAPEOEC_01080	3.66e-190	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
IIAPEOEC_01081	1.35e-164	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IIAPEOEC_01082	1.36e-212	-	-	-	K	-	-	-	LysR substrate binding domain
IIAPEOEC_01083	1.64e-220	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IIAPEOEC_01084	3.3e-106	lytE	-	-	M	-	-	-	Lysin motif
IIAPEOEC_01085	1.44e-191	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IIAPEOEC_01086	1.36e-261	oatA	-	-	I	-	-	-	Acyltransferase
IIAPEOEC_01087	2.55e-68	-	-	-	-	-	-	-	-
IIAPEOEC_01088	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIAPEOEC_01089	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIAPEOEC_01090	1.14e-149	ybbR	-	-	S	-	-	-	YbbR-like protein
IIAPEOEC_01091	2.67e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIAPEOEC_01092	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IIAPEOEC_01093	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IIAPEOEC_01094	1.11e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIAPEOEC_01095	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IIAPEOEC_01096	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IIAPEOEC_01097	1.07e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIAPEOEC_01098	2.02e-140	-	-	-	-	-	-	-	-
IIAPEOEC_01099	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IIAPEOEC_01100	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIAPEOEC_01101	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IIAPEOEC_01102	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IIAPEOEC_01103	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IIAPEOEC_01104	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIAPEOEC_01105	8.38e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIAPEOEC_01106	4.22e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IIAPEOEC_01107	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIAPEOEC_01108	3.82e-23	-	-	-	-	-	-	-	-
IIAPEOEC_01109	2.16e-26	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
IIAPEOEC_01110	2.77e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IIAPEOEC_01111	5.09e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IIAPEOEC_01112	1.62e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
IIAPEOEC_01113	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
IIAPEOEC_01114	2.94e-148	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IIAPEOEC_01115	4.63e-174	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IIAPEOEC_01116	8.95e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
IIAPEOEC_01117	1.74e-178	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IIAPEOEC_01118	5.63e-196	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIAPEOEC_01119	1.61e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IIAPEOEC_01120	5.35e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIAPEOEC_01121	1.23e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIAPEOEC_01122	1.66e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IIAPEOEC_01123	6.87e-295	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IIAPEOEC_01124	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIAPEOEC_01125	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIAPEOEC_01126	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IIAPEOEC_01127	3.87e-282	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IIAPEOEC_01128	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IIAPEOEC_01129	3.19e-66	ylxQ	-	-	J	-	-	-	ribosomal protein
IIAPEOEC_01130	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIAPEOEC_01131	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIAPEOEC_01132	3.22e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIAPEOEC_01133	1.69e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IIAPEOEC_01134	9.07e-313	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IIAPEOEC_01135	3.04e-66	-	-	-	IQ	ko:K18333	ko00051,ko01120,map00051,map01120	ko00000,ko00001	KR domain
IIAPEOEC_01136	2.07e-24	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IIAPEOEC_01137	1.6e-74	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IIAPEOEC_01138	5.19e-83	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IIAPEOEC_01139	2.54e-287	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
IIAPEOEC_01141	6.73e-86	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
IIAPEOEC_01142	2.36e-222	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIAPEOEC_01143	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IIAPEOEC_01144	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IIAPEOEC_01145	7.76e-146	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IIAPEOEC_01146	1.79e-71	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
IIAPEOEC_01147	7.77e-204	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
IIAPEOEC_01148	4.01e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IIAPEOEC_01149	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
IIAPEOEC_01150	1e-215	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIAPEOEC_01152	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIAPEOEC_01153	1.78e-167	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
IIAPEOEC_01154	1.36e-136	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IIAPEOEC_01155	6.44e-240	-	-	-	I	-	-	-	Alpha beta
IIAPEOEC_01156	4.01e-154	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
IIAPEOEC_01157	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
IIAPEOEC_01158	2.63e-208	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
IIAPEOEC_01159	7.76e-188	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IIAPEOEC_01160	0.0	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IIAPEOEC_01161	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
IIAPEOEC_01162	7.54e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
IIAPEOEC_01163	3.93e-60	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
IIAPEOEC_01164	1.61e-250	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IIAPEOEC_01165	1.21e-266	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
IIAPEOEC_01166	3e-223	citR	-	-	K	-	-	-	sugar-binding domain protein
IIAPEOEC_01167	3.17e-314	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IIAPEOEC_01168	5.68e-211	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IIAPEOEC_01169	1.58e-314	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IIAPEOEC_01170	5.36e-282	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IIAPEOEC_01171	2.48e-117	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IIAPEOEC_01172	4.64e-235	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
IIAPEOEC_01173	1.26e-288	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
IIAPEOEC_01174	1.37e-99	mleR	-	-	K	-	-	-	LysR family
IIAPEOEC_01175	1.16e-307	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
IIAPEOEC_01176	2.35e-119	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
IIAPEOEC_01177	4.61e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IIAPEOEC_01178	1.66e-215	-	-	-	-	-	-	-	-
IIAPEOEC_01179	4.69e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
IIAPEOEC_01180	4.22e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IIAPEOEC_01181	3.22e-135	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
IIAPEOEC_01182	8.63e-93	-	-	-	F	-	-	-	Nudix hydrolase
IIAPEOEC_01183	2.84e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IIAPEOEC_01184	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IIAPEOEC_01185	1.58e-226	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IIAPEOEC_01186	3.29e-146	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
IIAPEOEC_01187	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IIAPEOEC_01188	6.91e-234	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
IIAPEOEC_01189	4.22e-214	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
IIAPEOEC_01190	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIAPEOEC_01191	6.63e-94	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
IIAPEOEC_01192	1.18e-140	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IIAPEOEC_01194	1.57e-260	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
IIAPEOEC_01195	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IIAPEOEC_01196	5.66e-231	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IIAPEOEC_01197	3.76e-193	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIAPEOEC_01198	1.6e-171	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_01200	4.39e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IIAPEOEC_01201	1.02e-295	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
IIAPEOEC_01202	6.52e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IIAPEOEC_01203	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IIAPEOEC_01204	1.54e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IIAPEOEC_01205	1.13e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IIAPEOEC_01206	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IIAPEOEC_01207	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIAPEOEC_01208	7.75e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIAPEOEC_01209	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIAPEOEC_01210	1.51e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IIAPEOEC_01211	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IIAPEOEC_01212	1.33e-219	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
IIAPEOEC_01213	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIAPEOEC_01214	4.81e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIAPEOEC_01215	6.79e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IIAPEOEC_01216	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IIAPEOEC_01217	1.41e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
IIAPEOEC_01218	9.93e-17	-	-	-	K	-	-	-	transcriptional regulator
IIAPEOEC_01219	4.62e-288	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IIAPEOEC_01220	2.68e-130	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
IIAPEOEC_01221	4.31e-76	-	-	-	S	-	-	-	branched-chain amino acid
IIAPEOEC_01222	6.89e-177	-	-	-	E	-	-	-	AzlC protein
IIAPEOEC_01223	2.83e-261	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIAPEOEC_01224	4.91e-264	hpk31	-	-	T	-	-	-	Histidine kinase
IIAPEOEC_01225	1.68e-155	vanR	-	-	K	-	-	-	response regulator
IIAPEOEC_01226	7.97e-77	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
IIAPEOEC_01229	1.41e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIAPEOEC_01230	5.43e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIAPEOEC_01231	4.59e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IIAPEOEC_01232	1.07e-203	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IIAPEOEC_01233	2.92e-245	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IIAPEOEC_01235	4.71e-96	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
IIAPEOEC_01236	5.51e-116	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
IIAPEOEC_01237	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
IIAPEOEC_01238	7.65e-39	-	-	-	S	ko:K08987	-	ko00000	membrane
IIAPEOEC_01239	3.68e-67	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
IIAPEOEC_01240	6.27e-68	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
IIAPEOEC_01241	1.28e-132	-	-	-	Q	-	-	-	Methyltransferase domain
IIAPEOEC_01243	3.19e-132	-	-	-	S	-	-	-	CAAX protease self-immunity
IIAPEOEC_01244	1.29e-120	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IIAPEOEC_01245	2.11e-171	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IIAPEOEC_01247	2.29e-18	-	-	-	K	-	-	-	Transcriptional regulator
IIAPEOEC_01248	3.27e-129	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IIAPEOEC_01249	2.67e-274	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIAPEOEC_01250	1.17e-131	-	-	-	-	-	-	-	-
IIAPEOEC_01251	2.41e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IIAPEOEC_01252	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IIAPEOEC_01253	1.01e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IIAPEOEC_01254	1.95e-175	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IIAPEOEC_01255	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIAPEOEC_01256	4.51e-206	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IIAPEOEC_01257	1.8e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IIAPEOEC_01258	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
IIAPEOEC_01259	7.29e-242	mocA	-	-	S	-	-	-	Oxidoreductase
IIAPEOEC_01260	4.79e-307	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IIAPEOEC_01262	2.78e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
IIAPEOEC_01263	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IIAPEOEC_01264	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IIAPEOEC_01265	1.44e-79	-	-	-	M	-	-	-	Glycosyl transferase 4-like
IIAPEOEC_01266	8.42e-114	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
IIAPEOEC_01267	1.88e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IIAPEOEC_01268	7.37e-148	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IIAPEOEC_01269	8.81e-166	epsB	-	-	M	-	-	-	biosynthesis protein
IIAPEOEC_01270	2.08e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIAPEOEC_01271	9.9e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIAPEOEC_01272	2.03e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IIAPEOEC_01273	3.53e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIAPEOEC_01274	1.78e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IIAPEOEC_01275	5.29e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IIAPEOEC_01276	6.65e-209	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IIAPEOEC_01277	3.53e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IIAPEOEC_01278	5.42e-184	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IIAPEOEC_01279	2.1e-270	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
IIAPEOEC_01280	4.55e-315	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IIAPEOEC_01281	9.02e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_01282	5.16e-284	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIAPEOEC_01284	2.84e-239	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IIAPEOEC_01286	4.3e-314	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIAPEOEC_01287	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
IIAPEOEC_01288	5.01e-276	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIAPEOEC_01289	1.29e-190	-	-	-	S	-	-	-	HNH endonuclease
IIAPEOEC_01290	2.43e-100	-	-	-	S	-	-	-	Phage terminase, small subunit
IIAPEOEC_01291	0.0	-	-	-	S	-	-	-	Phage Terminase
IIAPEOEC_01293	7.8e-300	-	-	-	S	-	-	-	Phage portal protein
IIAPEOEC_01294	6.88e-87	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
IIAPEOEC_01295	6.31e-254	-	-	-	S	-	-	-	peptidase activity
IIAPEOEC_01296	4.29e-64	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IIAPEOEC_01297	1.26e-29	-	-	-	S	-	-	-	Phage head-tail joining protein
IIAPEOEC_01298	2.49e-49	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IIAPEOEC_01299	1.9e-54	-	-	-	-	-	-	-	-
IIAPEOEC_01300	4.54e-144	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
IIAPEOEC_01302	2.14e-19	-	-	-	-	-	-	-	-
IIAPEOEC_01303	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
IIAPEOEC_01304	3.77e-201	-	-	-	S	-	-	-	Phage tail protein
IIAPEOEC_01305	4.34e-135	-	-	-	M	-	-	-	Prophage endopeptidase tail
IIAPEOEC_01306	4.81e-47	spoIVFA	-	GT2,GT4	D	ko:K05802,ko:K06401,ko:K20444,ko:K22051	-	ko00000,ko01000,ko01005,ko02000	peptidase
IIAPEOEC_01310	1.47e-69	-	-	-	-	-	-	-	-
IIAPEOEC_01313	2.37e-33	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
IIAPEOEC_01314	4.37e-258	-	-	-	S	-	-	-	peptidoglycan catabolic process
IIAPEOEC_01315	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IIAPEOEC_01316	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIAPEOEC_01317	4.68e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIAPEOEC_01318	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
IIAPEOEC_01319	9.16e-105	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IIAPEOEC_01321	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IIAPEOEC_01322	3.07e-239	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
IIAPEOEC_01323	4.16e-211	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
IIAPEOEC_01324	3.86e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIAPEOEC_01325	7.3e-212	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IIAPEOEC_01326	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IIAPEOEC_01327	3.45e-144	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IIAPEOEC_01328	1.03e-142	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IIAPEOEC_01329	7.63e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
IIAPEOEC_01330	3.27e-123	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IIAPEOEC_01331	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIAPEOEC_01332	1.3e-262	yacL	-	-	S	-	-	-	domain protein
IIAPEOEC_01333	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIAPEOEC_01334	3.92e-129	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IIAPEOEC_01335	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IIAPEOEC_01336	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIAPEOEC_01337	3.52e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIAPEOEC_01338	1.2e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IIAPEOEC_01339	2.06e-282	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IIAPEOEC_01340	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IIAPEOEC_01341	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIAPEOEC_01342	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIAPEOEC_01343	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IIAPEOEC_01344	9.48e-204	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IIAPEOEC_01345	3.36e-110	-	-	-	L	-	-	-	nuclease
IIAPEOEC_01346	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIAPEOEC_01347	1.96e-52	-	-	-	-	-	-	-	-
IIAPEOEC_01348	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IIAPEOEC_01349	6.45e-240	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
IIAPEOEC_01350	2.16e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIAPEOEC_01351	2.34e-208	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IIAPEOEC_01352	2.38e-157	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_01353	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IIAPEOEC_01354	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IIAPEOEC_01355	3.57e-289	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIAPEOEC_01356	1.43e-66	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIAPEOEC_01357	8.05e-136	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIAPEOEC_01358	9.16e-35	-	-	-	-	-	-	-	-
IIAPEOEC_01359	6.33e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIAPEOEC_01360	1.73e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIAPEOEC_01361	7.21e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIAPEOEC_01362	3.13e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IIAPEOEC_01363	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
IIAPEOEC_01364	4.12e-164	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
IIAPEOEC_01365	1.48e-218	-	-	-	GK	-	-	-	ROK family
IIAPEOEC_01366	1.31e-53	-	-	-	-	-	-	-	-
IIAPEOEC_01367	6.95e-105	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IIAPEOEC_01369	8.32e-109	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
IIAPEOEC_01371	2.76e-218	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
IIAPEOEC_01372	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IIAPEOEC_01373	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
IIAPEOEC_01374	5.43e-231	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIAPEOEC_01375	4.56e-80	-	-	-	-	-	-	-	-
IIAPEOEC_01376	1.4e-282	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IIAPEOEC_01377	6.63e-122	-	-	-	V	-	-	-	VanZ like family
IIAPEOEC_01378	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIAPEOEC_01379	3.92e-83	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IIAPEOEC_01380	1.89e-41	-	-	-	-	-	-	-	-
IIAPEOEC_01381	1.31e-212	-	-	-	H	-	-	-	geranyltranstransferase activity
IIAPEOEC_01383	3.55e-172	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IIAPEOEC_01384	1.11e-208	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
IIAPEOEC_01385	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IIAPEOEC_01386	1.51e-97	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
IIAPEOEC_01387	3.56e-187	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
IIAPEOEC_01388	1.47e-287	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIAPEOEC_01389	1.78e-240	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIAPEOEC_01390	2.51e-98	yphH	-	-	S	-	-	-	Cupin domain
IIAPEOEC_01391	4.74e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIAPEOEC_01392	1.34e-197	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IIAPEOEC_01393	1.08e-64	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IIAPEOEC_01394	3.08e-125	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IIAPEOEC_01395	2.39e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IIAPEOEC_01396	2.76e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IIAPEOEC_01397	6.64e-173	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IIAPEOEC_01398	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IIAPEOEC_01399	4.16e-144	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
IIAPEOEC_01401	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIAPEOEC_01402	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IIAPEOEC_01403	2.21e-255	-	-	-	-	-	-	-	-
IIAPEOEC_01404	3.06e-203	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IIAPEOEC_01405	4.03e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IIAPEOEC_01406	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IIAPEOEC_01407	1.87e-101	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IIAPEOEC_01410	3.91e-31	-	-	-	-	-	-	-	-
IIAPEOEC_01411	2.23e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IIAPEOEC_01412	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IIAPEOEC_01413	0.0	-	-	-	EGP	-	-	-	Major Facilitator
IIAPEOEC_01414	1.06e-123	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IIAPEOEC_01415	5.67e-65	-	-	-	-	-	-	-	-
IIAPEOEC_01416	1.26e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIAPEOEC_01417	4.23e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIAPEOEC_01418	4.39e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IIAPEOEC_01419	6.62e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IIAPEOEC_01420	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IIAPEOEC_01421	9.88e-57	-	-	-	-	-	-	-	-
IIAPEOEC_01422	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IIAPEOEC_01423	9.22e-37	-	-	-	S	-	-	-	Domain of unknown function DUF302
IIAPEOEC_01424	3.25e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIAPEOEC_01425	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IIAPEOEC_01426	8.2e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
IIAPEOEC_01427	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IIAPEOEC_01429	7.78e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_01430	2.08e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
IIAPEOEC_01431	8.52e-216	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIAPEOEC_01432	6.44e-129	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
IIAPEOEC_01433	9.92e-26	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IIAPEOEC_01434	9.97e-95	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IIAPEOEC_01435	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IIAPEOEC_01436	2.3e-239	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IIAPEOEC_01437	5.18e-210	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
IIAPEOEC_01438	3.3e-122	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IIAPEOEC_01440	5.97e-219	yueF	-	-	S	-	-	-	AI-2E family transporter
IIAPEOEC_01441	6.59e-204	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IIAPEOEC_01442	4.14e-09	-	-	-	-	-	-	-	-
IIAPEOEC_01443	8.17e-67	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
IIAPEOEC_01445	1.66e-305	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IIAPEOEC_01446	7.32e-247	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
IIAPEOEC_01447	1.4e-27	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIAPEOEC_01448	4.47e-113	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
IIAPEOEC_01449	6.36e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAPEOEC_01450	2.8e-256	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IIAPEOEC_01451	3.35e-134	-	-	-	C	-	-	-	aldo keto reductase
IIAPEOEC_01452	1.56e-137	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
IIAPEOEC_01454	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIAPEOEC_01455	6.35e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IIAPEOEC_01456	6.21e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
IIAPEOEC_01457	9.18e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IIAPEOEC_01458	8.58e-146	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IIAPEOEC_01459	5.8e-124	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IIAPEOEC_01460	1.63e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIAPEOEC_01461	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IIAPEOEC_01462	9.76e-87	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIAPEOEC_01463	1.16e-242	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIAPEOEC_01464	5.5e-80	-	-	-	-	-	-	-	-
IIAPEOEC_01466	1.12e-94	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IIAPEOEC_01467	4.62e-210	-	-	-	L	-	-	-	Z1 domain
IIAPEOEC_01468	1.05e-149	-	-	-	-	-	-	-	-
IIAPEOEC_01469	3.13e-49	-	-	-	-	-	-	-	-
IIAPEOEC_01470	5.22e-88	-	-	-	-	-	-	-	-
IIAPEOEC_01472	4.52e-176	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
IIAPEOEC_01473	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IIAPEOEC_01474	7.63e-72	-	-	-	S	-	-	-	MazG-like family
IIAPEOEC_01475	1.47e-136	-	-	-	I	-	-	-	PAP2 superfamily
IIAPEOEC_01476	1.11e-94	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IIAPEOEC_01477	1.28e-46	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IIAPEOEC_01478	2.11e-31	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IIAPEOEC_01479	5.84e-123	-	-	-	-	-	-	-	-
IIAPEOEC_01480	2e-284	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIAPEOEC_01481	1.06e-207	-	-	-	V	-	-	-	Beta-lactamase enzyme family
IIAPEOEC_01482	0.0	potE	-	-	E	-	-	-	Amino Acid
IIAPEOEC_01483	1.37e-300	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IIAPEOEC_01484	1.21e-89	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
IIAPEOEC_01485	2.4e-314	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IIAPEOEC_01486	1.24e-130	-	-	-	K	-	-	-	DNA-templated transcription, initiation
IIAPEOEC_01488	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
IIAPEOEC_01489	6.59e-76	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
IIAPEOEC_01492	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IIAPEOEC_01493	3.7e-148	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIAPEOEC_01494	1.79e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IIAPEOEC_01495	1.41e-114	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
IIAPEOEC_01496	4.06e-58	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
IIAPEOEC_01497	5.54e-144	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IIAPEOEC_01498	1.89e-74	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
IIAPEOEC_01500	6.53e-139	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IIAPEOEC_01501	1.35e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IIAPEOEC_01502	1.18e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIAPEOEC_01503	1.34e-126	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IIAPEOEC_01504	1.11e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IIAPEOEC_01505	6.46e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIAPEOEC_01506	1.02e-201	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IIAPEOEC_01511	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
IIAPEOEC_01512	2.49e-211	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IIAPEOEC_01513	2.12e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IIAPEOEC_01514	7.99e-126	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
IIAPEOEC_01515	4.22e-299	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
IIAPEOEC_01516	2.23e-121	-	-	-	M	-	-	-	PFAM NLP P60 protein
IIAPEOEC_01517	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IIAPEOEC_01518	1.34e-179	-	-	-	-	-	-	-	-
IIAPEOEC_01519	1.4e-236	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IIAPEOEC_01520	1.26e-271	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IIAPEOEC_01521	1.32e-91	-	-	-	-	-	-	-	-
IIAPEOEC_01522	5.99e-67	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IIAPEOEC_01523	1.06e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IIAPEOEC_01524	5.87e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IIAPEOEC_01525	1.34e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
IIAPEOEC_01526	1.13e-226	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIAPEOEC_01527	2.58e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IIAPEOEC_01528	1.27e-290	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IIAPEOEC_01529	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIAPEOEC_01530	2.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IIAPEOEC_01531	5.36e-07	-	-	-	-	-	-	-	-
IIAPEOEC_01532	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IIAPEOEC_01533	6.85e-164	-	-	-	F	-	-	-	NUDIX domain
IIAPEOEC_01534	7.08e-142	pncA	-	-	Q	-	-	-	Isochorismatase family
IIAPEOEC_01535	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIAPEOEC_01536	3.84e-124	-	-	-	S	-	-	-	Pfam:DUF3816
IIAPEOEC_01537	3.72e-83	-	-	-	L	-	-	-	Resolvase, N-terminal domain
IIAPEOEC_01538	3.01e-116	-	-	-	L	-	-	-	Probable transposase
IIAPEOEC_01539	7.8e-181	-	-	-	G	-	-	-	MucBP domain
IIAPEOEC_01540	7.22e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIAPEOEC_01541	6.05e-206	-	-	-	EG	-	-	-	EamA-like transporter family
IIAPEOEC_01542	6.84e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IIAPEOEC_01543	3.67e-05	-	-	-	S	-	-	-	Protein of unknown function DUF262
IIAPEOEC_01549	1.88e-54	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
IIAPEOEC_01550	2.4e-180	-	-	-	S	-	-	-	calcium ion binding
IIAPEOEC_01551	9.69e-99	-	-	-	S	-	-	-	Single-strand binding protein family
IIAPEOEC_01552	2.88e-218	-	-	-	S	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
IIAPEOEC_01553	2.36e-224	-	-	-	S	-	-	-	DNA metabolic process
IIAPEOEC_01562	7.82e-154	-	-	-	S	-	-	-	DNA binding
IIAPEOEC_01563	7.18e-80	-	-	-	K	-	-	-	Peptidase S24-like
IIAPEOEC_01564	1.46e-78	-	-	-	-	-	-	-	-
IIAPEOEC_01565	3.71e-129	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
IIAPEOEC_01566	3.76e-06	-	-	-	-	-	-	-	-
IIAPEOEC_01567	2.26e-23	-	-	-	L	-	-	-	nuclease
IIAPEOEC_01568	1.32e-47	-	-	-	-	-	-	-	-
IIAPEOEC_01569	4.51e-260	-	-	-	S	-	-	-	Phage integrase family
IIAPEOEC_01570	3.7e-139	-	-	-	S	-	-	-	VIT family
IIAPEOEC_01571	7.13e-110	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
IIAPEOEC_01572	1.18e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
IIAPEOEC_01573	8.89e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IIAPEOEC_01574	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIAPEOEC_01575	1.35e-76	-	-	-	-	-	-	-	-
IIAPEOEC_01576	1.49e-91	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IIAPEOEC_01577	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IIAPEOEC_01578	6.43e-148	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IIAPEOEC_01579	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IIAPEOEC_01580	3.52e-160	-	-	-	K	-	-	-	transcriptional regulator, ArsR family
IIAPEOEC_01581	2.44e-217	abf	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
IIAPEOEC_01582	1.62e-215	lacY	-	-	G	ko:K02532	-	ko00000,ko02000	Oligosaccharide H symporter
IIAPEOEC_01583	9.98e-252	XK27_08315	-	-	M	-	-	-	Sulfatase
IIAPEOEC_01584	2.78e-190	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IIAPEOEC_01585	2.53e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
IIAPEOEC_01587	8.93e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IIAPEOEC_01588	7.03e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
IIAPEOEC_01589	3.86e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IIAPEOEC_01590	2.23e-47	-	-	-	M	-	-	-	biosynthesis protein
IIAPEOEC_01591	8.2e-81	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IIAPEOEC_01592	5.44e-89	-	-	-	-	-	-	-	-
IIAPEOEC_01593	2.47e-106	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IIAPEOEC_01594	5.17e-93	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
IIAPEOEC_01595	3.14e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IIAPEOEC_01596	3.75e-275	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IIAPEOEC_01597	6.08e-85	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
IIAPEOEC_01598	2.07e-196	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
IIAPEOEC_01599	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIAPEOEC_01600	8.91e-166	-	-	-	-	-	-	-	-
IIAPEOEC_01601	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIAPEOEC_01602	3.13e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IIAPEOEC_01603	6.61e-186	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IIAPEOEC_01604	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IIAPEOEC_01605	0.0	potE	-	-	E	-	-	-	Amino Acid
IIAPEOEC_01606	1.58e-239	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IIAPEOEC_01607	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
IIAPEOEC_01608	1.25e-208	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IIAPEOEC_01609	8.41e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
IIAPEOEC_01610	1.72e-40	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IIAPEOEC_01611	7.5e-159	-	-	-	S	-	-	-	Putative threonine/serine exporter
IIAPEOEC_01612	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IIAPEOEC_01613	2.47e-146	-	-	-	I	-	-	-	phosphatase
IIAPEOEC_01614	3.45e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IIAPEOEC_01616	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IIAPEOEC_01617	6.66e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
IIAPEOEC_01623	1.06e-12	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIAPEOEC_01624	1.51e-92	-	-	-	IQ	-	-	-	reductase
IIAPEOEC_01625	7.14e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IIAPEOEC_01626	1.12e-67	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IIAPEOEC_01627	6.64e-81	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
IIAPEOEC_01628	6.92e-97	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
IIAPEOEC_01629	3.27e-168	XK27_07210	-	-	S	-	-	-	B3 4 domain
IIAPEOEC_01630	8.7e-71	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
IIAPEOEC_01632	3.55e-62	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IIAPEOEC_01633	2.42e-06	-	-	-	K	-	-	-	LysR substrate binding domain
IIAPEOEC_01634	3.86e-71	-	-	-	C	-	-	-	Aldo keto reductase
IIAPEOEC_01635	4.15e-05	-	-	-	S	-	-	-	CsbD-like
IIAPEOEC_01637	2.12e-36	-	-	-	C	-	-	-	Aldo/keto reductase family
IIAPEOEC_01638	2.02e-116	-	-	-	P	-	-	-	Cadmium resistance transporter
IIAPEOEC_01639	8.37e-42	ydzE	-	-	EG	-	-	-	spore germination
IIAPEOEC_01640	8.58e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IIAPEOEC_01641	2.62e-300	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IIAPEOEC_01644	1.13e-09	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IIAPEOEC_01646	1.25e-11	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIAPEOEC_01647	4.15e-65	-	-	-	-	-	-	-	-
IIAPEOEC_01648	1.64e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IIAPEOEC_01649	1.88e-310	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIAPEOEC_01650	4.28e-273	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IIAPEOEC_01651	1.67e-138	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIAPEOEC_01652	2.73e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIAPEOEC_01653	4.49e-196	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IIAPEOEC_01654	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
IIAPEOEC_01655	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IIAPEOEC_01656	8.02e-62	-	-	-	-	-	-	-	-
IIAPEOEC_01657	7.37e-16	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
IIAPEOEC_01658	1.03e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIAPEOEC_01659	5.85e-169	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIAPEOEC_01660	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIAPEOEC_01661	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IIAPEOEC_01662	2.3e-49	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
IIAPEOEC_01667	3.08e-53	-	-	-	L	-	-	-	MULE transposase domain
IIAPEOEC_01668	2.8e-189	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
IIAPEOEC_01669	3.65e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
IIAPEOEC_01670	2e-129	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IIAPEOEC_01672	8.37e-27	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIAPEOEC_01673	7.36e-204	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IIAPEOEC_01674	1.16e-60	ywjB	-	-	H	-	-	-	RibD C-terminal domain
IIAPEOEC_01675	4.39e-148	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIAPEOEC_01676	6.11e-88	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IIAPEOEC_01677	1.75e-58	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IIAPEOEC_01678	1.85e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
IIAPEOEC_01679	1.08e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
IIAPEOEC_01680	2.15e-86	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
IIAPEOEC_01681	5.81e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIAPEOEC_01682	1.74e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIAPEOEC_01683	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
IIAPEOEC_01684	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IIAPEOEC_01685	7.18e-151	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
IIAPEOEC_01686	8.03e-61	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IIAPEOEC_01687	4.18e-34	nlhH_1	-	-	I	ko:K01066	-	ko00000,ko01000	acetylesterase activity
IIAPEOEC_01688	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIAPEOEC_01689	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IIAPEOEC_01690	9.61e-249	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
IIAPEOEC_01691	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IIAPEOEC_01692	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
IIAPEOEC_01693	3.84e-76	-	-	-	GM	-	-	-	NmrA-like family
IIAPEOEC_01694	3.32e-209	-	-	-	K	-	-	-	LysR substrate binding domain
IIAPEOEC_01695	1.84e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
IIAPEOEC_01696	1.25e-140	-	-	-	-	-	-	-	-
IIAPEOEC_01698	2.41e-76	-	-	-	-	-	-	-	-
IIAPEOEC_01699	1.42e-234	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IIAPEOEC_01700	2.77e-21	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
IIAPEOEC_01701	4.59e-100	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
IIAPEOEC_01702	7.78e-126	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IIAPEOEC_01703	1.75e-134	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAPEOEC_01704	1.38e-128	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IIAPEOEC_01705	5.23e-69	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IIAPEOEC_01706	0.0	-	-	-	E	-	-	-	amino acid
IIAPEOEC_01707	7.08e-205	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IIAPEOEC_01708	1.25e-32	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IIAPEOEC_01709	1.07e-300	-	-	-	F	ko:K03458	-	ko00000	Permease
IIAPEOEC_01710	9.88e-205	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
IIAPEOEC_01711	1.22e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIAPEOEC_01712	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IIAPEOEC_01713	1.02e-141	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IIAPEOEC_01714	9.64e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IIAPEOEC_01715	2.04e-141	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
IIAPEOEC_01716	6.61e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IIAPEOEC_01717	3.65e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IIAPEOEC_01718	1.4e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IIAPEOEC_01719	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IIAPEOEC_01720	6.2e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IIAPEOEC_01721	3.35e-79	-	-	-	L	-	-	-	Resolvase, N terminal domain
IIAPEOEC_01725	2.92e-257	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
IIAPEOEC_01726	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
IIAPEOEC_01727	8.03e-170	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IIAPEOEC_01728	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IIAPEOEC_01729	3.39e-194	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IIAPEOEC_01730	4.13e-22	-	-	-	G	-	-	-	Major Facilitator
IIAPEOEC_01731	3.31e-39	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IIAPEOEC_01732	1.99e-76	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IIAPEOEC_01733	9.9e-69	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IIAPEOEC_01734	4.7e-100	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IIAPEOEC_01735	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
IIAPEOEC_01736	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
IIAPEOEC_01737	1.47e-195	-	-	-	D	-	-	-	nuclear chromosome segregation
IIAPEOEC_01738	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IIAPEOEC_01739	1.53e-208	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IIAPEOEC_01742	3.84e-148	-	-	-	-	-	-	-	-
IIAPEOEC_01743	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IIAPEOEC_01744	1.82e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IIAPEOEC_01745	1.53e-287	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IIAPEOEC_01746	6.44e-139	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IIAPEOEC_01747	2.89e-251	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IIAPEOEC_01748	2.91e-63	-	-	-	C	-	-	-	FMN binding
IIAPEOEC_01751	8.72e-279	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IIAPEOEC_01752	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IIAPEOEC_01753	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAPEOEC_01754	7.53e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IIAPEOEC_01755	1.54e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAPEOEC_01756	8.66e-313	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIAPEOEC_01757	1.2e-82	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IIAPEOEC_01758	2.46e-102	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
IIAPEOEC_01759	1.53e-19	-	-	-	-	-	-	-	-
IIAPEOEC_01760	1.29e-299	-	-	-	L	ko:K07485	-	ko00000	Transposase
IIAPEOEC_01764	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIAPEOEC_01765	3.28e-21	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IIAPEOEC_01766	6.95e-53	-	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIAPEOEC_01767	4.46e-211	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IIAPEOEC_01768	1.67e-204	-	-	-	L	-	-	-	Integrase core domain
IIAPEOEC_01769	2.79e-139	-	-	-	L	-	-	-	Bacterial dnaA protein
IIAPEOEC_01770	2.49e-31	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIAPEOEC_01771	2.96e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
IIAPEOEC_01781	8.43e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
IIAPEOEC_01782	2.29e-68	-	-	-	S	-	-	-	Cupredoxin-like domain
IIAPEOEC_01783	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IIAPEOEC_01784	7.26e-35	-	-	-	EGP	-	-	-	Major Facilitator
IIAPEOEC_01785	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
IIAPEOEC_01786	1.22e-205	XK27_09800	-	-	I	-	-	-	Acyltransferase family
IIAPEOEC_01787	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IIAPEOEC_01788	6.61e-136	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IIAPEOEC_01789	2.2e-80	-	-	-	M	-	-	-	Glycosyl transferases group 1
IIAPEOEC_01790	2.78e-223	epsH	-	-	M	-	-	-	Glycosyl transferase family 2
IIAPEOEC_01791	4.26e-225	-	-	-	S	-	-	-	Protein conserved in bacteria
IIAPEOEC_01792	2.23e-221	-	-	-	S	-	-	-	EpsG family
IIAPEOEC_01793	1.44e-87	-	-	-	S	-	-	-	Flavodoxin
IIAPEOEC_01794	1.08e-51	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIAPEOEC_01795	8.75e-134	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIAPEOEC_01796	5.03e-181	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IIAPEOEC_01797	4.44e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IIAPEOEC_01798	4.8e-119	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
IIAPEOEC_01801	1.63e-82	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
IIAPEOEC_01802	7.62e-142	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IIAPEOEC_01803	4.29e-35	yitW	-	-	S	-	-	-	DNA methyltransferase
IIAPEOEC_01804	6.78e-225	-	-	-	-	-	-	-	-
IIAPEOEC_01805	5.74e-285	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIAPEOEC_01806	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIAPEOEC_01807	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IIAPEOEC_01808	8.13e-206	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
IIAPEOEC_01809	2.32e-233	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIAPEOEC_01810	1.38e-61	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIAPEOEC_01811	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IIAPEOEC_01812	8.34e-101	-	-	-	-	-	-	-	-
IIAPEOEC_01813	1.05e-59	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
IIAPEOEC_01814	9.03e-79	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
IIAPEOEC_01815	7.07e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IIAPEOEC_01816	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIAPEOEC_01817	2.33e-51	-	-	-	S	-	-	-	Cytochrome B5
IIAPEOEC_01818	1.97e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IIAPEOEC_01819	4.65e-58	yodA	-	-	S	-	-	-	Tautomerase enzyme
IIAPEOEC_01820	3.79e-07	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
IIAPEOEC_01822	2.69e-148	pnb	-	-	C	-	-	-	nitroreductase
IIAPEOEC_01823	2.39e-106	-	-	-	S	-	-	-	Carboxymuconolactone decarboxylase family
IIAPEOEC_01827	5.28e-13	-	-	-	-	-	-	-	-
IIAPEOEC_01829	4.78e-296	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IIAPEOEC_01830	1.02e-256	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IIAPEOEC_01833	3.07e-12	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IIAPEOEC_01834	2.64e-51	-	-	-	-	-	-	-	-
IIAPEOEC_01835	1.85e-120	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IIAPEOEC_01836	1.53e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIAPEOEC_01837	7.44e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IIAPEOEC_01838	7.99e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IIAPEOEC_01839	2.01e-87	-	-	-	M	-	-	-	LysM domain protein
IIAPEOEC_01840	2e-109	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
IIAPEOEC_01841	7.69e-100	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IIAPEOEC_01842	4.74e-23	-	-	-	-	-	-	-	-
IIAPEOEC_01843	1.39e-40	-	-	-	S	-	-	-	Transglycosylase associated protein
IIAPEOEC_01844	8.47e-106	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIAPEOEC_01845	3.04e-32	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
IIAPEOEC_01846	1.31e-121	-	-	-	-	-	-	-	-
IIAPEOEC_01847	9.78e-73	-	-	-	K	-	-	-	Transcriptional regulator
IIAPEOEC_01849	2.91e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IIAPEOEC_01851	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IIAPEOEC_01852	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
IIAPEOEC_01853	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IIAPEOEC_01854	1.76e-146	-	-	-	K	-	-	-	Transcriptional regulator
IIAPEOEC_01855	2.21e-229	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAPEOEC_01858	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IIAPEOEC_01859	2.7e-18	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IIAPEOEC_01860	4.58e-246	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIAPEOEC_01861	7.74e-278	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IIAPEOEC_01862	4.73e-42	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IIAPEOEC_01863	2.35e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IIAPEOEC_01864	6.08e-42	-	-	-	S	-	-	-	Cytochrome B5
IIAPEOEC_01865	9.82e-18	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
IIAPEOEC_01866	1.07e-23	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
IIAPEOEC_01868	1.02e-19	-	-	-	-	-	-	-	-
IIAPEOEC_01869	7.87e-88	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
IIAPEOEC_01870	2.84e-97	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IIAPEOEC_01871	5.2e-143	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IIAPEOEC_01873	1.58e-57	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IIAPEOEC_01874	5.36e-61	-	-	-	M	-	-	-	Acetyltransferase (Isoleucine patch superfamily)
IIAPEOEC_01875	1.8e-151	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
IIAPEOEC_01876	6.35e-99	-	-	-	O	-	-	-	Bacterial dnaA protein
IIAPEOEC_01877	7.85e-139	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IIAPEOEC_01880	2.95e-22	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IIAPEOEC_01881	7.34e-27	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase