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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IKIEMMBD_00001	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IKIEMMBD_00002	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IKIEMMBD_00003	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
IKIEMMBD_00004	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IKIEMMBD_00005	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
IKIEMMBD_00006	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IKIEMMBD_00007	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IKIEMMBD_00008	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IKIEMMBD_00009	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKIEMMBD_00010	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
IKIEMMBD_00011	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IKIEMMBD_00012	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IKIEMMBD_00013	2.04e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IKIEMMBD_00014	2.58e-192	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IKIEMMBD_00015	2.27e-98	-	-	-	S	-	-	-	Bacterial PH domain
IKIEMMBD_00016	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
IKIEMMBD_00017	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IKIEMMBD_00018	1.52e-143	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
IKIEMMBD_00019	1.78e-225	yyaD	-	-	S	-	-	-	Membrane
IKIEMMBD_00020	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00021	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IKIEMMBD_00022	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IKIEMMBD_00023	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IKIEMMBD_00024	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IKIEMMBD_00025	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IKIEMMBD_00026	1.91e-183	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IKIEMMBD_00027	2.49e-229	ccpB	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00028	5.7e-87	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKIEMMBD_00029	7.68e-129	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
IKIEMMBD_00030	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
IKIEMMBD_00031	1.42e-213	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IKIEMMBD_00032	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
IKIEMMBD_00033	3.45e-315	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_00034	2.12e-137	yyaP	-	-	H	-	-	-	RibD C-terminal domain
IKIEMMBD_00035	1.28e-86	-	-	-	S	-	-	-	YjbR
IKIEMMBD_00036	2.72e-119	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
IKIEMMBD_00037	1.74e-124	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
IKIEMMBD_00038	2.07e-90	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IKIEMMBD_00039	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
IKIEMMBD_00040	5.08e-163	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IKIEMMBD_00041	8.22e-96	yybC	-	-	-	-	-	-	-
IKIEMMBD_00042	3.1e-101	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IKIEMMBD_00043	9.21e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00044	2.49e-276	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_00045	1.2e-163	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
IKIEMMBD_00046	5.02e-87	-	-	-	S	-	-	-	SnoaL-like domain
IKIEMMBD_00047	5.62e-181	-	-	-	-	-	-	-	-
IKIEMMBD_00048	4.38e-142	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
IKIEMMBD_00049	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_00051	3.67e-80	-	-	-	-	-	-	-	-
IKIEMMBD_00052	1.4e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
IKIEMMBD_00053	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00054	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
IKIEMMBD_00056	1.5e-204	yybS	-	-	S	-	-	-	membrane
IKIEMMBD_00057	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IKIEMMBD_00058	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IKIEMMBD_00059	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IKIEMMBD_00060	2.32e-280	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
IKIEMMBD_00061	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
IKIEMMBD_00063	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IKIEMMBD_00064	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IKIEMMBD_00065	1.34e-98	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKIEMMBD_00066	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IKIEMMBD_00071	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_00072	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_00073	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00074	6.94e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00075	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IKIEMMBD_00076	1.56e-277	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IKIEMMBD_00077	3.11e-42	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IKIEMMBD_00078	1.07e-96	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IKIEMMBD_00079	6.75e-122	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
IKIEMMBD_00080	2.14e-213	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IKIEMMBD_00081	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IKIEMMBD_00082	2.89e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
IKIEMMBD_00083	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IKIEMMBD_00084	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IKIEMMBD_00086	3.54e-238	-	-	-	S	-	-	-	aspartate phosphatase
IKIEMMBD_00087	3.69e-111	yycN	-	-	K	-	-	-	Acetyltransferase
IKIEMMBD_00088	1.96e-168	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IKIEMMBD_00089	5.11e-265	yycP	-	-	-	-	-	-	-
IKIEMMBD_00090	4.53e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IKIEMMBD_00092	8.21e-67	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IKIEMMBD_00093	1.43e-54	-	-	-	S	-	-	-	LlaJI restriction endonuclease
IKIEMMBD_00094	6.97e-115	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
IKIEMMBD_00095	3.24e-203	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
IKIEMMBD_00096	3.2e-186	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
IKIEMMBD_00098	2.89e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IKIEMMBD_00099	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
IKIEMMBD_00100	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IKIEMMBD_00101	5.49e-152	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IKIEMMBD_00102	4.13e-24	-	-	-	-	-	-	-	-
IKIEMMBD_00103	6.34e-165	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_00104	9.47e-24	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_00105	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IKIEMMBD_00106	1.11e-237	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
IKIEMMBD_00107	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
IKIEMMBD_00108	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
IKIEMMBD_00109	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IKIEMMBD_00110	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IKIEMMBD_00111	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IKIEMMBD_00112	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
IKIEMMBD_00113	4.71e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IKIEMMBD_00114	1.21e-243	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
IKIEMMBD_00115	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
IKIEMMBD_00116	6.51e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
IKIEMMBD_00117	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IKIEMMBD_00118	5.01e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_00119	3.91e-130	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IKIEMMBD_00120	6.05e-250	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
IKIEMMBD_00121	1.08e-285	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IKIEMMBD_00122	4.03e-99	yxaI	-	-	S	-	-	-	membrane protein domain
IKIEMMBD_00123	3.24e-82	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
IKIEMMBD_00124	5.06e-114	yxaL	-	-	S	-	-	-	PQQ-like domain
IKIEMMBD_00125	5.51e-30	yxaI	-	-	S	-	-	-	membrane protein domain
IKIEMMBD_00127	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IKIEMMBD_00128	3.66e-275	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IKIEMMBD_00129	1.45e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IKIEMMBD_00131	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
IKIEMMBD_00132	5.91e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IKIEMMBD_00133	2.39e-61	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
IKIEMMBD_00135	2.04e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IKIEMMBD_00136	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IKIEMMBD_00137	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IKIEMMBD_00138	4.9e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IKIEMMBD_00139	1.23e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IKIEMMBD_00140	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IKIEMMBD_00141	1.23e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IKIEMMBD_00142	1.63e-295	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
IKIEMMBD_00143	1.55e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IKIEMMBD_00144	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
IKIEMMBD_00145	1.09e-186	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IKIEMMBD_00146	4.02e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IKIEMMBD_00147	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_00148	7.73e-231	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_00149	1.1e-180	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_00150	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IKIEMMBD_00151	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IKIEMMBD_00152	4.99e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IKIEMMBD_00153	9.65e-91	-	-	-	-	-	-	-	-
IKIEMMBD_00154	7.57e-28	yxeD	-	-	-	-	-	-	-
IKIEMMBD_00155	7.32e-42	yxeE	-	-	-	-	-	-	-
IKIEMMBD_00158	1.34e-192	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
IKIEMMBD_00159	6.41e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IKIEMMBD_00160	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKIEMMBD_00161	2.99e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKIEMMBD_00162	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IKIEMMBD_00163	7.75e-135	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IKIEMMBD_00164	9.69e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_00165	1.67e-271	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IKIEMMBD_00166	6.54e-316	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
IKIEMMBD_00167	6.34e-255	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
IKIEMMBD_00168	9.11e-198	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
IKIEMMBD_00169	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IKIEMMBD_00170	1.18e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IKIEMMBD_00171	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IKIEMMBD_00172	4.02e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
IKIEMMBD_00173	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IKIEMMBD_00174	1.14e-229	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IKIEMMBD_00175	2.61e-298	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
IKIEMMBD_00176	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IKIEMMBD_00177	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
IKIEMMBD_00178	4.06e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IKIEMMBD_00179	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IKIEMMBD_00180	1.78e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
IKIEMMBD_00181	5.43e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
IKIEMMBD_00182	1.22e-155	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
IKIEMMBD_00184	2.81e-26	-	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00186	4.99e-291	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
IKIEMMBD_00187	2.65e-102	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
IKIEMMBD_00188	2.29e-63	-	-	-	-	-	-	-	-
IKIEMMBD_00189	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_00190	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IKIEMMBD_00191	9.93e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
IKIEMMBD_00192	2.77e-35	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IKIEMMBD_00193	3.52e-113	-	-	-	-	-	-	-	-
IKIEMMBD_00195	2.01e-75	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IKIEMMBD_00196	2.2e-28	-	-	-	-	-	-	-	-
IKIEMMBD_00197	1.7e-209	yxxF	-	-	EG	-	-	-	EamA-like transporter family
IKIEMMBD_00198	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
IKIEMMBD_00200	3.31e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
IKIEMMBD_00201	1.31e-70	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IKIEMMBD_00202	8.65e-275	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IKIEMMBD_00203	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IKIEMMBD_00204	3.8e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
IKIEMMBD_00205	3.07e-142	-	-	-	-	-	-	-	-
IKIEMMBD_00206	2.31e-192	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IKIEMMBD_00207	3.06e-184	bglS	-	-	M	-	-	-	licheninase activity
IKIEMMBD_00208	8.14e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IKIEMMBD_00209	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IKIEMMBD_00210	6.54e-63	yxiS	-	-	-	-	-	-	-
IKIEMMBD_00211	1.4e-131	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
IKIEMMBD_00212	2.98e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IKIEMMBD_00213	3.9e-182	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
IKIEMMBD_00214	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
IKIEMMBD_00215	6.34e-166	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IKIEMMBD_00216	1.39e-149	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IKIEMMBD_00217	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IKIEMMBD_00218	6.32e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IKIEMMBD_00219	7.42e-278	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IKIEMMBD_00220	2.88e-111	yxjI	-	-	S	-	-	-	LURP-one-related
IKIEMMBD_00223	5.24e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IKIEMMBD_00224	9.01e-147	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
IKIEMMBD_00225	1.13e-257	-	-	-	T	-	-	-	Signal transduction histidine kinase
IKIEMMBD_00226	5.82e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
IKIEMMBD_00227	2.47e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IKIEMMBD_00228	1.17e-98	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
IKIEMMBD_00229	6.56e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IKIEMMBD_00230	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IKIEMMBD_00231	3.89e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IKIEMMBD_00232	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IKIEMMBD_00233	7.49e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
IKIEMMBD_00235	0.0	-	-	-	O	-	-	-	Peptidase family M48
IKIEMMBD_00236	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
IKIEMMBD_00237	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IKIEMMBD_00238	8.19e-244	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
IKIEMMBD_00239	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
IKIEMMBD_00240	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
IKIEMMBD_00241	3.58e-200	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IKIEMMBD_00242	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
IKIEMMBD_00243	1.29e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_00244	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
IKIEMMBD_00245	2.92e-42	-	-	-	-	-	-	-	-
IKIEMMBD_00246	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
IKIEMMBD_00247	2.35e-210	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_00248	5.4e-177	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IKIEMMBD_00249	2.59e-276	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
IKIEMMBD_00250	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IKIEMMBD_00251	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IKIEMMBD_00252	8.94e-28	yxzF	-	-	-	-	-	-	-
IKIEMMBD_00253	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IKIEMMBD_00254	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
IKIEMMBD_00255	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKIEMMBD_00256	1.58e-50	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_00257	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IKIEMMBD_00258	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IKIEMMBD_00259	6.86e-177	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_00260	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IKIEMMBD_00261	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_00262	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
IKIEMMBD_00263	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_00264	1.34e-208	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IKIEMMBD_00265	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
IKIEMMBD_00266	2.27e-164	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
IKIEMMBD_00267	5.58e-64	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IKIEMMBD_00268	1.44e-116	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IKIEMMBD_00269	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
IKIEMMBD_00270	3.02e-295	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IKIEMMBD_00271	3.57e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00272	8.23e-157	ywaF	-	-	S	-	-	-	Integral membrane protein
IKIEMMBD_00273	4.41e-215	gspA	-	-	M	-	-	-	General stress
IKIEMMBD_00274	9.07e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IKIEMMBD_00275	1.69e-311	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_00276	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IKIEMMBD_00277	4.27e-310	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKIEMMBD_00278	3.41e-159	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
IKIEMMBD_00279	4.01e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
IKIEMMBD_00280	6.63e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
IKIEMMBD_00281	3.13e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
IKIEMMBD_00282	4.31e-277	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
IKIEMMBD_00283	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
IKIEMMBD_00284	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IKIEMMBD_00285	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00286	1.32e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IKIEMMBD_00287	1.74e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IKIEMMBD_00288	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
IKIEMMBD_00289	2.42e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
IKIEMMBD_00290	4.4e-308	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
IKIEMMBD_00291	1.8e-141	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IKIEMMBD_00292	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKIEMMBD_00293	4.29e-64	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
IKIEMMBD_00295	3.42e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
IKIEMMBD_00296	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
IKIEMMBD_00297	1.31e-289	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IKIEMMBD_00298	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IKIEMMBD_00299	5.11e-49	ydaS	-	-	S	-	-	-	membrane
IKIEMMBD_00300	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IKIEMMBD_00301	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IKIEMMBD_00302	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IKIEMMBD_00303	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IKIEMMBD_00304	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
IKIEMMBD_00305	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IKIEMMBD_00306	9.4e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
IKIEMMBD_00307	8.11e-237	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKIEMMBD_00308	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IKIEMMBD_00310	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IKIEMMBD_00311	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
IKIEMMBD_00312	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_00313	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IKIEMMBD_00314	6.19e-39	ywdA	-	-	-	-	-	-	-
IKIEMMBD_00315	2.21e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IKIEMMBD_00316	6.52e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IKIEMMBD_00317	5.06e-145	ywdD	-	-	-	-	-	-	-
IKIEMMBD_00319	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
IKIEMMBD_00320	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IKIEMMBD_00321	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IKIEMMBD_00322	4.4e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
IKIEMMBD_00323	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
IKIEMMBD_00324	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
IKIEMMBD_00325	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IKIEMMBD_00326	1.15e-186	spsA	-	-	M	-	-	-	Spore Coat
IKIEMMBD_00327	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
IKIEMMBD_00328	7.52e-284	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
IKIEMMBD_00329	1.72e-209	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
IKIEMMBD_00330	6.52e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
IKIEMMBD_00331	4.64e-169	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
IKIEMMBD_00332	1.41e-240	spsG	-	-	M	-	-	-	Spore Coat
IKIEMMBD_00333	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IKIEMMBD_00334	5.26e-233	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IKIEMMBD_00335	1.41e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IKIEMMBD_00336	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
IKIEMMBD_00337	3.7e-101	-	-	-	-	-	-	-	-
IKIEMMBD_00338	2.11e-310	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IKIEMMBD_00339	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IKIEMMBD_00340	1.11e-249	rocB	-	-	E	-	-	-	arginine degradation protein
IKIEMMBD_00341	5.88e-146	rocB	-	-	E	-	-	-	arginine degradation protein
IKIEMMBD_00342	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IKIEMMBD_00343	1.55e-274	ywfA	-	-	EGP	-	-	-	-transporter
IKIEMMBD_00344	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IKIEMMBD_00345	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IKIEMMBD_00346	4.47e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_00347	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IKIEMMBD_00348	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IKIEMMBD_00349	1.56e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IKIEMMBD_00350	2.77e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
IKIEMMBD_00351	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
IKIEMMBD_00352	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
IKIEMMBD_00353	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_00354	4.16e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IKIEMMBD_00355	2.5e-201	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
IKIEMMBD_00356	6.58e-146	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
IKIEMMBD_00357	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
IKIEMMBD_00358	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
IKIEMMBD_00359	4.94e-114	ywgA	-	-	-	ko:K09388	-	ko00000	-
IKIEMMBD_00360	7.42e-102	yffB	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00361	2.62e-301	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
IKIEMMBD_00363	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IKIEMMBD_00364	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00365	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
IKIEMMBD_00366	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
IKIEMMBD_00367	7.83e-123	ywhD	-	-	S	-	-	-	YwhD family
IKIEMMBD_00368	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IKIEMMBD_00369	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IKIEMMBD_00370	1.73e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IKIEMMBD_00371	2.17e-37	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
IKIEMMBD_00373	1.32e-106	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IKIEMMBD_00374	3.63e-279	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
IKIEMMBD_00375	4.57e-304	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
IKIEMMBD_00377	7.81e-316	-	-	-	L	-	-	-	Peptidase, M16
IKIEMMBD_00378	2.32e-274	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
IKIEMMBD_00379	1.98e-296	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
IKIEMMBD_00380	1.75e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IKIEMMBD_00382	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
IKIEMMBD_00383	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
IKIEMMBD_00384	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00385	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IKIEMMBD_00386	2.78e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IKIEMMBD_00387	2.3e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
IKIEMMBD_00388	1.84e-179	ywiC	-	-	S	-	-	-	YwiC-like protein
IKIEMMBD_00389	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
IKIEMMBD_00390	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IKIEMMBD_00391	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
IKIEMMBD_00392	3.94e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
IKIEMMBD_00393	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
IKIEMMBD_00394	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IKIEMMBD_00395	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IKIEMMBD_00396	2.24e-123	ywjB	-	-	H	-	-	-	RibD C-terminal domain
IKIEMMBD_00397	1.32e-57	ywjC	-	-	-	-	-	-	-
IKIEMMBD_00398	1.63e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IKIEMMBD_00399	4.74e-287	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IKIEMMBD_00400	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
IKIEMMBD_00401	3.48e-268	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
IKIEMMBD_00402	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IKIEMMBD_00403	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IKIEMMBD_00404	2.24e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
IKIEMMBD_00405	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
IKIEMMBD_00406	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
IKIEMMBD_00407	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IKIEMMBD_00408	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IKIEMMBD_00409	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
IKIEMMBD_00410	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IKIEMMBD_00411	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IKIEMMBD_00412	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IKIEMMBD_00413	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IKIEMMBD_00414	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IKIEMMBD_00415	1.72e-116	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IKIEMMBD_00416	1.39e-88	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKIEMMBD_00417	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IKIEMMBD_00418	4.89e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IKIEMMBD_00420	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IKIEMMBD_00421	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
IKIEMMBD_00422	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
IKIEMMBD_00423	7.37e-251	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IKIEMMBD_00424	9.2e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IKIEMMBD_00425	4.54e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IKIEMMBD_00426	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
IKIEMMBD_00427	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IKIEMMBD_00428	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IKIEMMBD_00429	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IKIEMMBD_00430	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
IKIEMMBD_00431	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IKIEMMBD_00432	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IKIEMMBD_00433	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IKIEMMBD_00434	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IKIEMMBD_00435	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IKIEMMBD_00436	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IKIEMMBD_00437	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IKIEMMBD_00438	3.89e-72	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IKIEMMBD_00439	8.36e-113	ywmA	-	-	-	-	-	-	-
IKIEMMBD_00440	4.54e-45	ywzB	-	-	S	-	-	-	membrane
IKIEMMBD_00441	1.97e-173	ywmB	-	-	S	-	-	-	TATA-box binding
IKIEMMBD_00442	1e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IKIEMMBD_00443	4.84e-234	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
IKIEMMBD_00444	1.56e-156	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IKIEMMBD_00445	1.44e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IKIEMMBD_00447	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IKIEMMBD_00448	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IKIEMMBD_00449	3.1e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IKIEMMBD_00450	1.59e-109	ywmF	-	-	S	-	-	-	Peptidase M50
IKIEMMBD_00451	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
IKIEMMBD_00452	6.58e-11	-	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IKIEMMBD_00454	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
IKIEMMBD_00455	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
IKIEMMBD_00456	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IKIEMMBD_00457	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00458	6.14e-147	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IKIEMMBD_00459	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IKIEMMBD_00460	6.61e-182	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
IKIEMMBD_00461	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IKIEMMBD_00462	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
IKIEMMBD_00463	5.2e-21	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IKIEMMBD_00464	5.19e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
IKIEMMBD_00465	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IKIEMMBD_00466	1.9e-94	ywnJ	-	-	S	-	-	-	VanZ like family
IKIEMMBD_00467	4.23e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
IKIEMMBD_00468	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
IKIEMMBD_00469	6.5e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
IKIEMMBD_00470	5.04e-101	-	-	-	-	-	-	-	-
IKIEMMBD_00471	1.04e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
IKIEMMBD_00472	3.11e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
IKIEMMBD_00473	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
IKIEMMBD_00474	3.47e-304	ywoF	-	-	P	-	-	-	Right handed beta helix region
IKIEMMBD_00475	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_00476	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
IKIEMMBD_00477	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
IKIEMMBD_00478	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
IKIEMMBD_00479	4.85e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IKIEMMBD_00480	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IKIEMMBD_00481	7.42e-255	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
IKIEMMBD_00482	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IKIEMMBD_00483	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IKIEMMBD_00484	1.21e-08	ywpD	-	-	T	-	-	-	Histidine kinase
IKIEMMBD_00485	5.86e-123	ywpD	-	-	T	-	-	-	Histidine kinase
IKIEMMBD_00486	4.46e-66	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IKIEMMBD_00487	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
IKIEMMBD_00488	3.56e-86	ywpG	-	-	-	-	-	-	-
IKIEMMBD_00489	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IKIEMMBD_00490	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IKIEMMBD_00491	1.77e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IKIEMMBD_00492	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IKIEMMBD_00493	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
IKIEMMBD_00494	3.6e-25	-	-	-	-	-	-	-	-
IKIEMMBD_00495	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IKIEMMBD_00496	5.89e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IKIEMMBD_00497	5.03e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
IKIEMMBD_00498	1.82e-310	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IKIEMMBD_00499	1.99e-194	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
IKIEMMBD_00501	4.26e-51	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
IKIEMMBD_00502	1.68e-311	ywqJ	-	-	S	-	-	-	Pre-toxin TG
IKIEMMBD_00503	2.49e-62	-	-	-	-	-	-	-	-
IKIEMMBD_00504	2.67e-65	-	-	-	-	-	-	-	-
IKIEMMBD_00506	1.31e-13	-	-	-	-	-	-	-	-
IKIEMMBD_00507	5.73e-103	-	-	-	-	-	-	-	-
IKIEMMBD_00508	1.87e-158	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IKIEMMBD_00509	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00510	2.39e-126	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
IKIEMMBD_00512	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
IKIEMMBD_00513	4.53e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
IKIEMMBD_00514	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IKIEMMBD_00515	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IKIEMMBD_00516	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
IKIEMMBD_00517	8.79e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IKIEMMBD_00518	2.17e-16	-	-	-	-	-	-	-	-
IKIEMMBD_00519	4.57e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IKIEMMBD_00520	3.77e-181	cotB	-	-	-	ko:K06325	-	ko00000	-
IKIEMMBD_00521	1.06e-162	ywrJ	-	-	-	-	-	-	-
IKIEMMBD_00522	1.68e-281	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IKIEMMBD_00523	6.78e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
IKIEMMBD_00524	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IKIEMMBD_00525	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IKIEMMBD_00526	2.15e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
IKIEMMBD_00527	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
IKIEMMBD_00528	2.05e-121	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
IKIEMMBD_00529	1.28e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
IKIEMMBD_00530	1.93e-202	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IKIEMMBD_00531	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IKIEMMBD_00532	3.24e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IKIEMMBD_00533	4.35e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IKIEMMBD_00534	3.81e-227	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IKIEMMBD_00535	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
IKIEMMBD_00536	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
IKIEMMBD_00537	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IKIEMMBD_00538	4.62e-29	ywtC	-	-	-	-	-	-	-
IKIEMMBD_00539	3.92e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IKIEMMBD_00540	7.24e-205	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IKIEMMBD_00541	2.11e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00542	3.04e-313	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IKIEMMBD_00543	3.49e-270	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IKIEMMBD_00544	1.38e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IKIEMMBD_00545	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IKIEMMBD_00546	4.72e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IKIEMMBD_00547	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IKIEMMBD_00548	1.42e-235	tarL	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IKIEMMBD_00549	6.69e-110	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	M	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IKIEMMBD_00550	5.68e-186	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IKIEMMBD_00551	1.46e-134	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IKIEMMBD_00552	1.09e-116	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IKIEMMBD_00553	7.91e-110	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IKIEMMBD_00554	1.32e-73	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
IKIEMMBD_00555	6.32e-167	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IKIEMMBD_00556	1.46e-134	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IKIEMMBD_00557	1.49e-102	-	-	-	-	-	-	-	-
IKIEMMBD_00558	6.73e-165	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IKIEMMBD_00559	3.08e-181	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IKIEMMBD_00560	1.95e-167	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
IKIEMMBD_00561	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IKIEMMBD_00562	3.9e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IKIEMMBD_00564	3.43e-118	-	-	-	M	-	-	-	Glycosyl transferases group 1
IKIEMMBD_00565	1.48e-103	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IKIEMMBD_00566	1.01e-272	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IKIEMMBD_00567	2.85e-212	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IKIEMMBD_00568	9.07e-16	-	-	-	-	-	-	-	-
IKIEMMBD_00569	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
IKIEMMBD_00570	9.13e-265	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IKIEMMBD_00571	3.23e-109	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IKIEMMBD_00572	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IKIEMMBD_00573	5.94e-315	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKIEMMBD_00574	1.63e-278	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
IKIEMMBD_00575	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IKIEMMBD_00576	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
IKIEMMBD_00577	1.36e-145	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
IKIEMMBD_00578	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IKIEMMBD_00579	4.13e-297	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
IKIEMMBD_00580	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IKIEMMBD_00581	5.04e-225	yvhJ	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00582	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
IKIEMMBD_00583	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IKIEMMBD_00584	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKIEMMBD_00585	2.15e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00586	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IKIEMMBD_00587	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
IKIEMMBD_00588	9.99e-166	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
IKIEMMBD_00589	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
IKIEMMBD_00590	1.06e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
IKIEMMBD_00591	3.5e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
IKIEMMBD_00592	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
IKIEMMBD_00593	1.97e-199	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
IKIEMMBD_00594	4.19e-93	yviE	-	-	-	-	-	-	-
IKIEMMBD_00595	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IKIEMMBD_00596	2.58e-41	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IKIEMMBD_00597	8.01e-202	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IKIEMMBD_00598	1.1e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
IKIEMMBD_00599	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IKIEMMBD_00600	2.45e-89	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
IKIEMMBD_00601	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
IKIEMMBD_00602	9.14e-88	-	-	-	-	-	-	-	-
IKIEMMBD_00603	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IKIEMMBD_00604	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IKIEMMBD_00605	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IKIEMMBD_00606	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IKIEMMBD_00607	5.16e-72	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IKIEMMBD_00608	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
IKIEMMBD_00609	1.1e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IKIEMMBD_00610	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IKIEMMBD_00611	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
IKIEMMBD_00612	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IKIEMMBD_00613	5.01e-294	yvkA	-	-	P	-	-	-	-transporter
IKIEMMBD_00614	9.63e-130	yvkB	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00615	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
IKIEMMBD_00616	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00617	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IKIEMMBD_00618	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IKIEMMBD_00619	2.02e-101	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IKIEMMBD_00620	2.25e-45	yvkN	-	-	-	-	-	-	-
IKIEMMBD_00621	8.09e-65	yvlA	-	-	-	-	-	-	-
IKIEMMBD_00622	5.8e-221	yvlB	-	-	S	-	-	-	Putative adhesin
IKIEMMBD_00623	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IKIEMMBD_00624	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
IKIEMMBD_00625	6.05e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
IKIEMMBD_00626	8.46e-112	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IKIEMMBD_00627	2.49e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
IKIEMMBD_00628	1.88e-292	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IKIEMMBD_00629	9.4e-110	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IKIEMMBD_00630	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
IKIEMMBD_00631	1.75e-170	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
IKIEMMBD_00632	3.66e-167	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IKIEMMBD_00633	9.39e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IKIEMMBD_00634	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IKIEMMBD_00635	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IKIEMMBD_00636	6.16e-210	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
IKIEMMBD_00637	1.06e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IKIEMMBD_00638	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IKIEMMBD_00639	1.1e-153	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
IKIEMMBD_00640	2.49e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
IKIEMMBD_00641	2.82e-280	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IKIEMMBD_00642	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IKIEMMBD_00643	2.47e-290	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IKIEMMBD_00644	2.87e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IKIEMMBD_00645	1.15e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IKIEMMBD_00646	6.55e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IKIEMMBD_00647	2.29e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IKIEMMBD_00648	7.74e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
IKIEMMBD_00649	3.99e-116	-	-	-	S	-	-	-	Predicted membrane protein (DUF2339)
IKIEMMBD_00650	6.85e-91	-	-	-	-	-	-	-	-
IKIEMMBD_00652	3.87e-87	-	-	-	-	-	-	-	-
IKIEMMBD_00653	1.5e-110	-	-	-	-	-	-	-	-
IKIEMMBD_00654	0.0	-	-	-	-	-	-	-	-
IKIEMMBD_00656	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IKIEMMBD_00657	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
IKIEMMBD_00658	8.8e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
IKIEMMBD_00659	1.18e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IKIEMMBD_00660	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IKIEMMBD_00661	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IKIEMMBD_00662	2.73e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IKIEMMBD_00663	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IKIEMMBD_00664	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
IKIEMMBD_00665	4.83e-184	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
IKIEMMBD_00666	5.4e-43	-	-	-	-	-	-	-	-
IKIEMMBD_00667	3.84e-171	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_00668	1.96e-251	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IKIEMMBD_00669	5.21e-180	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_00670	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IKIEMMBD_00671	2.7e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IKIEMMBD_00672	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IKIEMMBD_00673	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IKIEMMBD_00674	4.54e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IKIEMMBD_00675	1.54e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IKIEMMBD_00676	1.32e-222	yvdE	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00677	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
IKIEMMBD_00678	1.4e-300	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IKIEMMBD_00679	1.74e-310	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IKIEMMBD_00680	6.84e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IKIEMMBD_00681	9.74e-198	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IKIEMMBD_00682	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
IKIEMMBD_00683	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IKIEMMBD_00684	3.92e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IKIEMMBD_00685	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IKIEMMBD_00687	2.71e-233	-	-	-	S	-	-	-	Patatin-like phospholipase
IKIEMMBD_00688	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
IKIEMMBD_00689	1.12e-121	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
IKIEMMBD_00690	4.21e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
IKIEMMBD_00691	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IKIEMMBD_00692	2.75e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00693	0.0	ybeC	-	-	E	-	-	-	amino acid
IKIEMMBD_00694	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IKIEMMBD_00695	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
IKIEMMBD_00696	7.19e-86	-	-	-	-	-	-	-	-
IKIEMMBD_00697	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
IKIEMMBD_00698	1.51e-163	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IKIEMMBD_00699	2.13e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
IKIEMMBD_00700	3.13e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IKIEMMBD_00702	9.08e-243	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
IKIEMMBD_00703	3.33e-84	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
IKIEMMBD_00704	3.57e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
IKIEMMBD_00705	6.82e-159	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IKIEMMBD_00706	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IKIEMMBD_00707	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IKIEMMBD_00708	1.4e-284	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
IKIEMMBD_00709	1.25e-201	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
IKIEMMBD_00710	4.48e-278	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IKIEMMBD_00711	8.82e-265	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
IKIEMMBD_00712	3.35e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IKIEMMBD_00713	5.7e-261	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
IKIEMMBD_00714	2.53e-241	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IKIEMMBD_00715	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKIEMMBD_00716	3.19e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IKIEMMBD_00717	1.1e-74	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IKIEMMBD_00718	2.6e-279	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IKIEMMBD_00719	4.36e-240	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
IKIEMMBD_00720	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
IKIEMMBD_00721	4.75e-304	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IKIEMMBD_00722	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IKIEMMBD_00723	3.25e-144	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
IKIEMMBD_00724	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_00725	3.86e-286	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IKIEMMBD_00726	2.15e-300	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IKIEMMBD_00727	1.28e-192	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IKIEMMBD_00728	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
IKIEMMBD_00729	2.91e-316	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
IKIEMMBD_00730	1.19e-262	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
IKIEMMBD_00731	2.08e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
IKIEMMBD_00733	6.37e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
IKIEMMBD_00734	5.01e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IKIEMMBD_00735	7.15e-257	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_00736	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKIEMMBD_00737	7.47e-174	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IKIEMMBD_00738	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IKIEMMBD_00739	1.45e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IKIEMMBD_00740	4.44e-251	-	-	-	S	-	-	-	Glycosyl hydrolase
IKIEMMBD_00741	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IKIEMMBD_00742	5.59e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
IKIEMMBD_00743	6.96e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00744	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKIEMMBD_00745	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
IKIEMMBD_00746	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IKIEMMBD_00747	5.69e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IKIEMMBD_00748	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IKIEMMBD_00749	1.62e-276	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IKIEMMBD_00750	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IKIEMMBD_00751	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
IKIEMMBD_00752	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IKIEMMBD_00753	2.8e-105	yvbK	-	-	K	-	-	-	acetyltransferase
IKIEMMBD_00754	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IKIEMMBD_00755	3.95e-157	yvbI	-	-	M	-	-	-	Membrane
IKIEMMBD_00756	1.03e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
IKIEMMBD_00757	7.95e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
IKIEMMBD_00758	1.74e-130	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IKIEMMBD_00759	9.25e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IKIEMMBD_00760	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IKIEMMBD_00761	1.74e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IKIEMMBD_00762	9.67e-137	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IKIEMMBD_00763	1.15e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IKIEMMBD_00764	8.21e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IKIEMMBD_00765	6.3e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IKIEMMBD_00766	2.27e-218	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IKIEMMBD_00767	2.26e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IKIEMMBD_00768	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IKIEMMBD_00769	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
IKIEMMBD_00770	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IKIEMMBD_00771	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
IKIEMMBD_00772	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
IKIEMMBD_00773	4.04e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
IKIEMMBD_00774	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
IKIEMMBD_00775	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
IKIEMMBD_00776	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IKIEMMBD_00777	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IKIEMMBD_00779	1.61e-181	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_00780	9.58e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IKIEMMBD_00781	5.85e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
IKIEMMBD_00782	4.07e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
IKIEMMBD_00783	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
IKIEMMBD_00784	2.95e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IKIEMMBD_00785	2.83e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IKIEMMBD_00786	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
IKIEMMBD_00787	3.66e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
IKIEMMBD_00788	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IKIEMMBD_00789	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IKIEMMBD_00790	5.71e-136	bdbD	-	-	O	-	-	-	Thioredoxin
IKIEMMBD_00791	6.67e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
IKIEMMBD_00792	2.34e-139	yvgT	-	-	S	-	-	-	membrane
IKIEMMBD_00794	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IKIEMMBD_00795	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IKIEMMBD_00796	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IKIEMMBD_00797	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
IKIEMMBD_00798	9.32e-112	yvgO	-	-	-	-	-	-	-
IKIEMMBD_00799	2.63e-202	yvgN	-	-	S	-	-	-	reductase
IKIEMMBD_00800	7.09e-153	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
IKIEMMBD_00801	4.07e-173	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
IKIEMMBD_00802	3.46e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
IKIEMMBD_00803	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
IKIEMMBD_00804	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IKIEMMBD_00805	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
IKIEMMBD_00806	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IKIEMMBD_00807	2.2e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IKIEMMBD_00808	1.21e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_00809	1.37e-225	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_00810	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IKIEMMBD_00811	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
IKIEMMBD_00812	5.42e-158	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_00813	7.7e-273	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IKIEMMBD_00814	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
IKIEMMBD_00815	5.34e-291	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IKIEMMBD_00816	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
IKIEMMBD_00817	7.02e-128	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
IKIEMMBD_00818	6.16e-33	-	-	-	-	-	-	-	-
IKIEMMBD_00819	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_00820	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
IKIEMMBD_00821	1.09e-218	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
IKIEMMBD_00822	3.51e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_00823	2.1e-218	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IKIEMMBD_00824	4.47e-235	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_00825	8.62e-308	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IKIEMMBD_00826	5.32e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
IKIEMMBD_00827	7.59e-287	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_00828	1.07e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
IKIEMMBD_00829	2.44e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IKIEMMBD_00830	2.59e-104	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IKIEMMBD_00831	2.33e-40	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IKIEMMBD_00832	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
IKIEMMBD_00833	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_00834	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKIEMMBD_00835	3.48e-249	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
IKIEMMBD_00836	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IKIEMMBD_00837	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IKIEMMBD_00838	1.06e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
IKIEMMBD_00839	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IKIEMMBD_00840	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_00841	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_00842	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_00843	3.58e-301	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IKIEMMBD_00844	1.07e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
IKIEMMBD_00845	8.69e-194	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_00846	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
IKIEMMBD_00847	4.94e-88	-	-	-	S	-	-	-	YusW-like protein
IKIEMMBD_00848	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IKIEMMBD_00849	7.12e-62	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
IKIEMMBD_00850	3.28e-201	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
IKIEMMBD_00851	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_00852	2.93e-85	yusQ	-	-	S	-	-	-	Tautomerase enzyme
IKIEMMBD_00853	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
IKIEMMBD_00854	4.47e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
IKIEMMBD_00855	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
IKIEMMBD_00856	2.23e-54	-	-	-	-	-	-	-	-
IKIEMMBD_00857	6.98e-211	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IKIEMMBD_00858	3.75e-12	-	-	-	S	-	-	-	YuzL-like protein
IKIEMMBD_00859	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
IKIEMMBD_00860	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
IKIEMMBD_00861	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IKIEMMBD_00862	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IKIEMMBD_00863	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IKIEMMBD_00864	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
IKIEMMBD_00865	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
IKIEMMBD_00866	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
IKIEMMBD_00867	8.84e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
IKIEMMBD_00868	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IKIEMMBD_00869	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
IKIEMMBD_00870	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IKIEMMBD_00871	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IKIEMMBD_00872	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IKIEMMBD_00873	4.3e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
IKIEMMBD_00874	1.14e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IKIEMMBD_00875	2.55e-100	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
IKIEMMBD_00876	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
IKIEMMBD_00877	7.18e-86	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKIEMMBD_00878	3.35e-56	-	-	-	-	-	-	-	-
IKIEMMBD_00880	4.36e-263	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
IKIEMMBD_00881	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
IKIEMMBD_00882	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IKIEMMBD_00883	5.79e-307	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IKIEMMBD_00884	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IKIEMMBD_00885	4.58e-215	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IKIEMMBD_00886	5.31e-206	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
IKIEMMBD_00887	6.13e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IKIEMMBD_00888	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IKIEMMBD_00889	1.32e-217	bsn	-	-	L	-	-	-	Ribonuclease
IKIEMMBD_00890	1.38e-293	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IKIEMMBD_00891	8.51e-306	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IKIEMMBD_00893	4.52e-237	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IKIEMMBD_00894	7.22e-142	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
IKIEMMBD_00895	4.78e-185	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IKIEMMBD_00896	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IKIEMMBD_00897	2.16e-125	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IKIEMMBD_00898	1.41e-79	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IKIEMMBD_00899	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IKIEMMBD_00900	1.65e-285	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IKIEMMBD_00901	8.08e-298	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
IKIEMMBD_00902	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
IKIEMMBD_00903	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IKIEMMBD_00904	1.52e-79	yunG	-	-	-	-	-	-	-
IKIEMMBD_00905	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
IKIEMMBD_00906	7.59e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IKIEMMBD_00907	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IKIEMMBD_00908	1.39e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
IKIEMMBD_00909	2.46e-171	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
IKIEMMBD_00910	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
IKIEMMBD_00911	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IKIEMMBD_00912	1.29e-142	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IKIEMMBD_00913	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00914	1.96e-98	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
IKIEMMBD_00915	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IKIEMMBD_00916	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IKIEMMBD_00917	1.55e-253	yutH	-	-	S	-	-	-	Spore coat protein
IKIEMMBD_00918	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IKIEMMBD_00919	1.05e-250	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IKIEMMBD_00920	4.96e-219	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IKIEMMBD_00921	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
IKIEMMBD_00922	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
IKIEMMBD_00923	6.61e-75	yuzD	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00924	4.54e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IKIEMMBD_00925	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
IKIEMMBD_00926	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IKIEMMBD_00927	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IKIEMMBD_00928	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
IKIEMMBD_00929	6.88e-116	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKIEMMBD_00930	6.97e-150	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
IKIEMMBD_00931	6.68e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IKIEMMBD_00933	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
IKIEMMBD_00934	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IKIEMMBD_00935	1.97e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
IKIEMMBD_00936	2.69e-150	yuiC	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00937	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
IKIEMMBD_00938	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IKIEMMBD_00939	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
IKIEMMBD_00940	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
IKIEMMBD_00941	1.94e-156	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
IKIEMMBD_00942	1.04e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
IKIEMMBD_00943	1.43e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_00944	8.56e-290	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IKIEMMBD_00945	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
IKIEMMBD_00946	3.83e-229	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
IKIEMMBD_00947	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_00948	4.08e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
IKIEMMBD_00949	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
IKIEMMBD_00950	3.85e-260	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IKIEMMBD_00951	1.03e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
IKIEMMBD_00952	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
IKIEMMBD_00953	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
IKIEMMBD_00954	4.28e-271	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
IKIEMMBD_00955	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IKIEMMBD_00956	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
IKIEMMBD_00957	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
IKIEMMBD_00958	3.53e-170	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_00959	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IKIEMMBD_00960	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
IKIEMMBD_00961	1.05e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
IKIEMMBD_00962	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
IKIEMMBD_00963	2.05e-42	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
IKIEMMBD_00964	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
IKIEMMBD_00965	2.19e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IKIEMMBD_00966	3.27e-134	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
IKIEMMBD_00967	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IKIEMMBD_00968	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
IKIEMMBD_00969	1.35e-07	-	-	-	-	-	-	-	-
IKIEMMBD_00970	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
IKIEMMBD_00971	5.77e-169	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
IKIEMMBD_00973	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_00974	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKIEMMBD_00975	7.81e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
IKIEMMBD_00976	9.92e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
IKIEMMBD_00977	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKIEMMBD_00978	2.47e-101	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKIEMMBD_00979	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKIEMMBD_00980	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKIEMMBD_00981	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKIEMMBD_00982	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IKIEMMBD_00983	2.46e-22	-	-	-	-	-	-	-	-
IKIEMMBD_00984	7.99e-309	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
IKIEMMBD_00985	8.13e-214	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IKIEMMBD_00986	6.39e-237	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IKIEMMBD_00987	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_00988	6.34e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
IKIEMMBD_00989	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IKIEMMBD_00990	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IKIEMMBD_00991	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
IKIEMMBD_00992	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_00993	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
IKIEMMBD_00994	1.08e-242	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
IKIEMMBD_00996	8.49e-150	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
IKIEMMBD_00997	2.92e-90	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
IKIEMMBD_00998	1.06e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_00999	6.99e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IKIEMMBD_01000	1.53e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
IKIEMMBD_01001	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
IKIEMMBD_01002	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_01003	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
IKIEMMBD_01004	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IKIEMMBD_01005	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
IKIEMMBD_01006	8.16e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
IKIEMMBD_01007	2.27e-290	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
IKIEMMBD_01008	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IKIEMMBD_01010	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
IKIEMMBD_01011	3.56e-233	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
IKIEMMBD_01012	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
IKIEMMBD_01013	2.16e-48	-	-	-	-	-	-	-	-
IKIEMMBD_01014	2.77e-149	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
IKIEMMBD_01015	2.52e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IKIEMMBD_01016	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IKIEMMBD_01017	3.79e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
IKIEMMBD_01018	3.52e-48	-	-	-	-	-	-	-	-
IKIEMMBD_01019	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IKIEMMBD_01020	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IKIEMMBD_01021	2.29e-295	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IKIEMMBD_01022	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IKIEMMBD_01023	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IKIEMMBD_01024	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
IKIEMMBD_01025	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IKIEMMBD_01026	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IKIEMMBD_01027	4.94e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
IKIEMMBD_01028	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
IKIEMMBD_01029	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IKIEMMBD_01030	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
IKIEMMBD_01031	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IKIEMMBD_01033	3.95e-113	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
IKIEMMBD_01034	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
IKIEMMBD_01035	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IKIEMMBD_01036	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
IKIEMMBD_01037	1.25e-299	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
IKIEMMBD_01038	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IKIEMMBD_01039	5.83e-118	yuaB	-	-	-	-	-	-	-
IKIEMMBD_01040	5.02e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
IKIEMMBD_01041	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IKIEMMBD_01042	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
IKIEMMBD_01043	4.08e-137	yuaD	-	-	-	-	-	-	-
IKIEMMBD_01044	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
IKIEMMBD_01045	5.63e-108	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
IKIEMMBD_01046	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
IKIEMMBD_01047	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
IKIEMMBD_01048	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IKIEMMBD_01049	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IKIEMMBD_01071	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IKIEMMBD_01072	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IKIEMMBD_01073	1.84e-238	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
IKIEMMBD_01074	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IKIEMMBD_01075	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IKIEMMBD_01076	2.31e-100	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
IKIEMMBD_01077	7.43e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
IKIEMMBD_01078	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
IKIEMMBD_01079	2.82e-262	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
IKIEMMBD_01081	2.05e-297	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
IKIEMMBD_01082	3.15e-230	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
IKIEMMBD_01083	1.67e-309	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IKIEMMBD_01084	1.7e-196	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IKIEMMBD_01085	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IKIEMMBD_01086	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IKIEMMBD_01087	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IKIEMMBD_01088	1.15e-195	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IKIEMMBD_01089	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IKIEMMBD_01090	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IKIEMMBD_01091	7.07e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IKIEMMBD_01092	9.26e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IKIEMMBD_01093	1.5e-179	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IKIEMMBD_01094	6.39e-297	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IKIEMMBD_01095	9.65e-194	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IKIEMMBD_01096	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
IKIEMMBD_01097	1.2e-240	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IKIEMMBD_01098	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IKIEMMBD_01099	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IKIEMMBD_01100	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IKIEMMBD_01101	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IKIEMMBD_01102	6.79e-95	ytkA	-	-	S	-	-	-	YtkA-like
IKIEMMBD_01104	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IKIEMMBD_01105	3.2e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
IKIEMMBD_01106	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IKIEMMBD_01107	1.09e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IKIEMMBD_01108	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IKIEMMBD_01109	7.95e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IKIEMMBD_01110	6.67e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IKIEMMBD_01111	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
IKIEMMBD_01112	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IKIEMMBD_01113	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IKIEMMBD_01114	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IKIEMMBD_01115	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IKIEMMBD_01116	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IKIEMMBD_01117	5.49e-191	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
IKIEMMBD_01118	1.09e-272	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
IKIEMMBD_01119	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
IKIEMMBD_01120	1.36e-243	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
IKIEMMBD_01121	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
IKIEMMBD_01123	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
IKIEMMBD_01124	1.03e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_01125	3.35e-222	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IKIEMMBD_01126	1.94e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
IKIEMMBD_01127	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_01128	8.05e-296	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IKIEMMBD_01129	7.76e-168	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_01130	1.07e-237	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
IKIEMMBD_01131	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_01132	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
IKIEMMBD_01133	2.32e-77	yttA	-	-	S	-	-	-	Pfam Transposase IS66
IKIEMMBD_01134	2.01e-267	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
IKIEMMBD_01135	5.43e-183	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IKIEMMBD_01136	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
IKIEMMBD_01137	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IKIEMMBD_01138	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
IKIEMMBD_01139	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IKIEMMBD_01140	8.93e-185	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IKIEMMBD_01141	4.75e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IKIEMMBD_01142	3.66e-312	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IKIEMMBD_01143	2.64e-243	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_01144	1.95e-220	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
IKIEMMBD_01145	9.13e-179	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IKIEMMBD_01146	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IKIEMMBD_01147	3.28e-278	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IKIEMMBD_01148	1.62e-160	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IKIEMMBD_01149	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IKIEMMBD_01150	1.57e-279	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IKIEMMBD_01151	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
IKIEMMBD_01152	6.19e-193	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IKIEMMBD_01153	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IKIEMMBD_01154	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_01155	5.35e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IKIEMMBD_01156	2.78e-277	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IKIEMMBD_01157	1.94e-93	yteS	-	-	G	-	-	-	transport
IKIEMMBD_01158	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
IKIEMMBD_01159	2.2e-149	yteU	-	-	S	-	-	-	Integral membrane protein
IKIEMMBD_01160	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
IKIEMMBD_01161	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
IKIEMMBD_01162	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
IKIEMMBD_01163	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKIEMMBD_01164	1.23e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IKIEMMBD_01165	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
IKIEMMBD_01166	8.04e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IKIEMMBD_01167	4.1e-254	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
IKIEMMBD_01168	1.73e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IKIEMMBD_01169	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
IKIEMMBD_01170	6.05e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IKIEMMBD_01171	4.29e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IKIEMMBD_01172	4.04e-211	ytlQ	-	-	-	-	-	-	-
IKIEMMBD_01173	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IKIEMMBD_01174	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IKIEMMBD_01175	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
IKIEMMBD_01176	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
IKIEMMBD_01177	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IKIEMMBD_01178	7.23e-192	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IKIEMMBD_01179	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IKIEMMBD_01180	6.75e-67	ytzB	-	-	S	-	-	-	small secreted protein
IKIEMMBD_01181	9.11e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
IKIEMMBD_01182	2.86e-102	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
IKIEMMBD_01183	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
IKIEMMBD_01184	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
IKIEMMBD_01185	7.25e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IKIEMMBD_01186	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IKIEMMBD_01187	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IKIEMMBD_01188	9.66e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IKIEMMBD_01189	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
IKIEMMBD_01190	3.17e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
IKIEMMBD_01191	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IKIEMMBD_01192	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IKIEMMBD_01193	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IKIEMMBD_01194	1.31e-160	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IKIEMMBD_01195	2.69e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
IKIEMMBD_01196	1.77e-151	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
IKIEMMBD_01197	3.46e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IKIEMMBD_01198	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IKIEMMBD_01199	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IKIEMMBD_01201	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IKIEMMBD_01202	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
IKIEMMBD_01203	1.13e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IKIEMMBD_01204	1.2e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_01205	1.52e-197	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IKIEMMBD_01206	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IKIEMMBD_01207	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IKIEMMBD_01208	1.22e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IKIEMMBD_01209	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IKIEMMBD_01210	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IKIEMMBD_01211	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IKIEMMBD_01212	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
IKIEMMBD_01213	5.66e-188	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IKIEMMBD_01214	1.13e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
IKIEMMBD_01215	7.91e-110	yteJ	-	-	S	-	-	-	RDD family
IKIEMMBD_01216	5.03e-150	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
IKIEMMBD_01217	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
IKIEMMBD_01218	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IKIEMMBD_01219	2.55e-222	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
IKIEMMBD_01220	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IKIEMMBD_01221	9.5e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
IKIEMMBD_01222	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IKIEMMBD_01223	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IKIEMMBD_01225	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_01226	4.53e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
IKIEMMBD_01227	2.77e-220	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
IKIEMMBD_01228	3.42e-129	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IKIEMMBD_01229	9.11e-195	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IKIEMMBD_01230	1.08e-187	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IKIEMMBD_01231	3.35e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IKIEMMBD_01232	4.57e-153	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IKIEMMBD_01233	5.43e-182	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IKIEMMBD_01234	2.51e-236	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKIEMMBD_01235	5.26e-63	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
IKIEMMBD_01236	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKIEMMBD_01237	2.31e-164	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
IKIEMMBD_01238	1.16e-303	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IKIEMMBD_01239	2.61e-205	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IKIEMMBD_01240	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
IKIEMMBD_01241	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
IKIEMMBD_01242	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
IKIEMMBD_01243	1.15e-39	-	-	-	-	-	-	-	-
IKIEMMBD_01244	5.12e-112	ytrI	-	-	-	-	-	-	-
IKIEMMBD_01245	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
IKIEMMBD_01246	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IKIEMMBD_01247	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IKIEMMBD_01248	1.46e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IKIEMMBD_01249	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IKIEMMBD_01250	6.6e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IKIEMMBD_01251	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IKIEMMBD_01252	1.1e-80	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
IKIEMMBD_01253	2.24e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
IKIEMMBD_01254	9.38e-95	ytwI	-	-	S	-	-	-	membrane
IKIEMMBD_01255	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IKIEMMBD_01256	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
IKIEMMBD_01257	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
IKIEMMBD_01258	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_01259	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
IKIEMMBD_01260	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IKIEMMBD_01261	3.88e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IKIEMMBD_01262	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IKIEMMBD_01263	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IKIEMMBD_01264	4.54e-205	ytbE	-	-	S	-	-	-	reductase
IKIEMMBD_01265	4.27e-257	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
IKIEMMBD_01266	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_01267	7.03e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IKIEMMBD_01268	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IKIEMMBD_01269	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IKIEMMBD_01270	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
IKIEMMBD_01271	1.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IKIEMMBD_01272	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
IKIEMMBD_01273	9.91e-205	ytxC	-	-	S	-	-	-	YtxC-like family
IKIEMMBD_01275	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IKIEMMBD_01276	1.2e-190	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IKIEMMBD_01277	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_01278	3.95e-166	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
IKIEMMBD_01279	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IKIEMMBD_01280	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IKIEMMBD_01282	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IKIEMMBD_01283	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IKIEMMBD_01284	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IKIEMMBD_01285	2.57e-59	ysdA	-	-	S	-	-	-	Membrane
IKIEMMBD_01286	2.29e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
IKIEMMBD_01287	8.77e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
IKIEMMBD_01288	4.56e-241	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IKIEMMBD_01289	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IKIEMMBD_01290	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
IKIEMMBD_01291	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IKIEMMBD_01292	6.06e-187	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
IKIEMMBD_01293	2.62e-282	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IKIEMMBD_01294	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IKIEMMBD_01295	6.77e-219	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IKIEMMBD_01296	7.39e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
IKIEMMBD_01297	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
IKIEMMBD_01298	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
IKIEMMBD_01300	5.13e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
IKIEMMBD_01301	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
IKIEMMBD_01302	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
IKIEMMBD_01303	2.62e-262	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
IKIEMMBD_01304	4.37e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
IKIEMMBD_01305	3.13e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IKIEMMBD_01306	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IKIEMMBD_01307	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IKIEMMBD_01308	2.96e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IKIEMMBD_01309	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IKIEMMBD_01310	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
IKIEMMBD_01311	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
IKIEMMBD_01312	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IKIEMMBD_01313	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
IKIEMMBD_01314	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IKIEMMBD_01315	2.44e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_01316	6.3e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
IKIEMMBD_01317	1.28e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
IKIEMMBD_01318	3.02e-228	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
IKIEMMBD_01320	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
IKIEMMBD_01321	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IKIEMMBD_01322	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IKIEMMBD_01323	1.61e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IKIEMMBD_01324	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IKIEMMBD_01325	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
IKIEMMBD_01326	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IKIEMMBD_01327	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IKIEMMBD_01328	2.65e-102	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
IKIEMMBD_01329	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_01330	9.26e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IKIEMMBD_01331	5.25e-193	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IKIEMMBD_01332	1.62e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
IKIEMMBD_01333	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IKIEMMBD_01334	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IKIEMMBD_01335	2.34e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IKIEMMBD_01337	5.58e-182	ysnF	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_01338	2.16e-103	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
IKIEMMBD_01340	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IKIEMMBD_01341	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IKIEMMBD_01342	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IKIEMMBD_01343	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IKIEMMBD_01344	7.43e-256	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IKIEMMBD_01345	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IKIEMMBD_01346	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IKIEMMBD_01347	3.19e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
IKIEMMBD_01348	7.28e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IKIEMMBD_01349	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IKIEMMBD_01350	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
IKIEMMBD_01351	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IKIEMMBD_01352	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IKIEMMBD_01353	3.35e-116	ysxD	-	-	-	-	-	-	-
IKIEMMBD_01354	2.74e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IKIEMMBD_01355	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
IKIEMMBD_01356	7.63e-221	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IKIEMMBD_01357	2.91e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IKIEMMBD_01358	1.51e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
IKIEMMBD_01359	2.04e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IKIEMMBD_01360	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
IKIEMMBD_01361	3.26e-250	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IKIEMMBD_01362	1.53e-35	-	-	-	-	-	-	-	-
IKIEMMBD_01363	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IKIEMMBD_01364	6.38e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IKIEMMBD_01365	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IKIEMMBD_01366	7.4e-212	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
IKIEMMBD_01367	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
IKIEMMBD_01368	1.97e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
IKIEMMBD_01369	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
IKIEMMBD_01370	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IKIEMMBD_01371	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
IKIEMMBD_01372	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IKIEMMBD_01373	6.84e-185	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IKIEMMBD_01374	1.5e-186	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IKIEMMBD_01375	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
IKIEMMBD_01376	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IKIEMMBD_01377	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
IKIEMMBD_01378	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IKIEMMBD_01379	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
IKIEMMBD_01380	5.59e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IKIEMMBD_01381	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IKIEMMBD_01382	2.89e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IKIEMMBD_01383	1.18e-121	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
IKIEMMBD_01384	5.56e-289	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IKIEMMBD_01385	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
IKIEMMBD_01386	4.34e-203	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
IKIEMMBD_01387	7.94e-273	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IKIEMMBD_01388	4.02e-216	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
IKIEMMBD_01389	1.47e-69	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IKIEMMBD_01390	2.37e-162	yebC	-	-	K	-	-	-	transcriptional regulatory protein
IKIEMMBD_01391	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
IKIEMMBD_01392	1.47e-66	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
IKIEMMBD_01394	3.17e-150	yrzF	-	-	T	-	-	-	serine threonine protein kinase
IKIEMMBD_01395	1.67e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IKIEMMBD_01396	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
IKIEMMBD_01397	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
IKIEMMBD_01398	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IKIEMMBD_01399	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IKIEMMBD_01400	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
IKIEMMBD_01401	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IKIEMMBD_01402	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IKIEMMBD_01403	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
IKIEMMBD_01404	1.07e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
IKIEMMBD_01405	1.23e-144	yrbG	-	-	S	-	-	-	membrane
IKIEMMBD_01406	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKIEMMBD_01407	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
IKIEMMBD_01408	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IKIEMMBD_01409	3.77e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IKIEMMBD_01410	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IKIEMMBD_01411	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IKIEMMBD_01412	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IKIEMMBD_01413	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IKIEMMBD_01414	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IKIEMMBD_01415	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
IKIEMMBD_01417	8.6e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IKIEMMBD_01418	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IKIEMMBD_01419	1.61e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IKIEMMBD_01420	2.44e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IKIEMMBD_01421	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_01422	1.87e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IKIEMMBD_01423	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IKIEMMBD_01424	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
IKIEMMBD_01425	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IKIEMMBD_01426	1.23e-108	yrrD	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_01427	8.4e-42	yrzR	-	-	-	-	-	-	-
IKIEMMBD_01428	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
IKIEMMBD_01429	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IKIEMMBD_01430	6.53e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IKIEMMBD_01431	1.01e-184	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IKIEMMBD_01432	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IKIEMMBD_01433	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
IKIEMMBD_01434	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IKIEMMBD_01435	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IKIEMMBD_01436	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IKIEMMBD_01437	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IKIEMMBD_01438	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IKIEMMBD_01439	5.69e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
IKIEMMBD_01440	9.33e-224	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IKIEMMBD_01441	7.66e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
IKIEMMBD_01442	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IKIEMMBD_01443	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IKIEMMBD_01444	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
IKIEMMBD_01445	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
IKIEMMBD_01446	7.02e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
IKIEMMBD_01447	3.44e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
IKIEMMBD_01448	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IKIEMMBD_01449	1.66e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
IKIEMMBD_01450	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IKIEMMBD_01451	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
IKIEMMBD_01452	6.05e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IKIEMMBD_01453	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IKIEMMBD_01454	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IKIEMMBD_01455	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
IKIEMMBD_01457	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
IKIEMMBD_01458	1.42e-113	yrhH	-	-	Q	-	-	-	methyltransferase
IKIEMMBD_01459	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
IKIEMMBD_01460	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IKIEMMBD_01461	6.07e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
IKIEMMBD_01462	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
IKIEMMBD_01463	4.99e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
IKIEMMBD_01464	8.2e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_01465	1.19e-193	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
IKIEMMBD_01466	4.63e-136	yrhP	-	-	E	-	-	-	LysE type translocator
IKIEMMBD_01467	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IKIEMMBD_01468	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
IKIEMMBD_01469	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IKIEMMBD_01470	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
IKIEMMBD_01471	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IKIEMMBD_01472	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IKIEMMBD_01473	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IKIEMMBD_01474	6.46e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IKIEMMBD_01475	5.86e-254	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
IKIEMMBD_01476	3.03e-40	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
IKIEMMBD_01477	9.08e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IKIEMMBD_01478	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
IKIEMMBD_01479	1.05e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
IKIEMMBD_01480	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IKIEMMBD_01481	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
IKIEMMBD_01482	1.2e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
IKIEMMBD_01483	5.45e-86	-	-	-	E	-	-	-	Glyoxalase-like domain
IKIEMMBD_01485	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
IKIEMMBD_01486	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
IKIEMMBD_01487	1.84e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
IKIEMMBD_01488	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKIEMMBD_01489	5.73e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IKIEMMBD_01490	5.95e-263	yraM	-	-	S	-	-	-	PrpF protein
IKIEMMBD_01491	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_01492	9.19e-287	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IKIEMMBD_01493	8.13e-238	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
IKIEMMBD_01494	1.69e-119	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_01495	1.8e-167	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IKIEMMBD_01497	5.63e-161	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
IKIEMMBD_01498	3.41e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IKIEMMBD_01499	7.32e-247	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IKIEMMBD_01500	1.21e-211	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
IKIEMMBD_01501	1.17e-117	yrdA	-	-	S	-	-	-	DinB family
IKIEMMBD_01503	2.99e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
IKIEMMBD_01504	7.38e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
IKIEMMBD_01506	1.01e-294	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IKIEMMBD_01507	2.73e-33	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
IKIEMMBD_01508	4.13e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
IKIEMMBD_01509	1.88e-175	azlC	-	-	E	-	-	-	AzlC protein
IKIEMMBD_01510	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
IKIEMMBD_01511	2.37e-290	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IKIEMMBD_01512	9.9e-208	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
IKIEMMBD_01513	1.75e-87	yodA	-	-	S	-	-	-	tautomerase
IKIEMMBD_01514	3.32e-210	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
IKIEMMBD_01515	4.11e-252	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
IKIEMMBD_01516	5.71e-203	-	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_01517	2e-215	yrdR	-	-	EG	-	-	-	EamA-like transporter family
IKIEMMBD_01518	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
IKIEMMBD_01519	1.39e-295	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IKIEMMBD_01520	1.71e-105	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
IKIEMMBD_01521	1.26e-267	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_01522	8.04e-191	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IKIEMMBD_01524	1.82e-137	yrkC	-	-	G	-	-	-	Cupin domain
IKIEMMBD_01525	1.65e-28	-	-	-	-	-	-	-	-
IKIEMMBD_01526	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_01527	1.96e-108	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
IKIEMMBD_01528	2.28e-126	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
IKIEMMBD_01529	1.4e-261	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
IKIEMMBD_01530	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
IKIEMMBD_01531	4.55e-156	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IKIEMMBD_01532	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
IKIEMMBD_01533	2.33e-125	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
IKIEMMBD_01534	1.49e-131	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IKIEMMBD_01535	1.19e-279	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IKIEMMBD_01536	3.4e-162	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
IKIEMMBD_01537	4.23e-305	yrkQ	-	-	T	-	-	-	Histidine kinase
IKIEMMBD_01538	6.16e-90	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
IKIEMMBD_01539	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKIEMMBD_01540	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IKIEMMBD_01541	1.1e-169	-	-	-	-	-	-	-	-
IKIEMMBD_01542	3.1e-216	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
IKIEMMBD_01543	1.62e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
IKIEMMBD_01544	6.58e-174	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IKIEMMBD_01545	9.11e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IKIEMMBD_01547	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
IKIEMMBD_01548	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IKIEMMBD_01549	4.01e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IKIEMMBD_01550	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
IKIEMMBD_01551	1.01e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IKIEMMBD_01552	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IKIEMMBD_01553	6.61e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IKIEMMBD_01554	1.63e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
IKIEMMBD_01555	1.1e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IKIEMMBD_01556	3.85e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
IKIEMMBD_01557	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IKIEMMBD_01558	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IKIEMMBD_01559	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
IKIEMMBD_01560	4.06e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IKIEMMBD_01561	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IKIEMMBD_01562	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IKIEMMBD_01563	3.88e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
IKIEMMBD_01564	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
IKIEMMBD_01565	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IKIEMMBD_01566	6.84e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IKIEMMBD_01567	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IKIEMMBD_01568	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IKIEMMBD_01569	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IKIEMMBD_01570	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IKIEMMBD_01571	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
IKIEMMBD_01572	1.38e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IKIEMMBD_01573	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
IKIEMMBD_01574	1.18e-200	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
IKIEMMBD_01575	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IKIEMMBD_01576	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
IKIEMMBD_01577	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
IKIEMMBD_01578	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
IKIEMMBD_01579	3.13e-79	yqfB	-	-	-	-	-	-	-
IKIEMMBD_01580	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
IKIEMMBD_01581	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
IKIEMMBD_01582	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
IKIEMMBD_01584	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
IKIEMMBD_01585	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IKIEMMBD_01586	4.75e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IKIEMMBD_01587	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IKIEMMBD_01588	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IKIEMMBD_01589	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
IKIEMMBD_01590	1.24e-185	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IKIEMMBD_01591	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IKIEMMBD_01592	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IKIEMMBD_01593	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
IKIEMMBD_01594	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IKIEMMBD_01595	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
IKIEMMBD_01596	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IKIEMMBD_01597	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IKIEMMBD_01598	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IKIEMMBD_01599	2.81e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IKIEMMBD_01600	6.25e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IKIEMMBD_01601	1.01e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IKIEMMBD_01602	7.31e-52	yqfQ	-	-	S	-	-	-	YqfQ-like protein
IKIEMMBD_01603	6.32e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IKIEMMBD_01604	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IKIEMMBD_01605	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
IKIEMMBD_01606	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IKIEMMBD_01607	2.47e-106	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
IKIEMMBD_01608	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
IKIEMMBD_01609	2.04e-81	yqfX	-	-	S	-	-	-	membrane
IKIEMMBD_01610	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IKIEMMBD_01611	2.84e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
IKIEMMBD_01612	2.74e-168	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IKIEMMBD_01613	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
IKIEMMBD_01614	6.48e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
IKIEMMBD_01615	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
IKIEMMBD_01616	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IKIEMMBD_01617	5.26e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IKIEMMBD_01618	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IKIEMMBD_01619	8.71e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IKIEMMBD_01620	8.04e-189	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IKIEMMBD_01621	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IKIEMMBD_01622	6.33e-93	yqzC	-	-	S	-	-	-	YceG-like family
IKIEMMBD_01623	3.42e-68	yqzD	-	-	-	-	-	-	-
IKIEMMBD_01625	9.8e-258	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
IKIEMMBD_01626	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IKIEMMBD_01627	1.88e-135	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IKIEMMBD_01628	3.38e-14	yqgO	-	-	-	-	-	-	-
IKIEMMBD_01629	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
IKIEMMBD_01630	8.83e-43	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
IKIEMMBD_01631	1.33e-229	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IKIEMMBD_01632	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IKIEMMBD_01633	2.5e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
IKIEMMBD_01634	8.99e-255	yqgU	-	-	-	-	-	-	-
IKIEMMBD_01635	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
IKIEMMBD_01636	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
IKIEMMBD_01637	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
IKIEMMBD_01638	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
IKIEMMBD_01639	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
IKIEMMBD_01641	2.49e-192	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IKIEMMBD_01642	9.56e-304	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IKIEMMBD_01643	8.73e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
IKIEMMBD_01644	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IKIEMMBD_01645	1.02e-217	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
IKIEMMBD_01646	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
IKIEMMBD_01647	3.65e-89	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
IKIEMMBD_01648	1.03e-77	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
IKIEMMBD_01649	5.84e-46	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IKIEMMBD_01650	6.26e-56	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
IKIEMMBD_01651	3.33e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
IKIEMMBD_01652	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IKIEMMBD_01653	8e-156	yqxM	-	-	-	ko:K19433	-	ko00000	-
IKIEMMBD_01654	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
IKIEMMBD_01655	6.08e-180	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
IKIEMMBD_01656	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
IKIEMMBD_01657	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
IKIEMMBD_01658	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
IKIEMMBD_01659	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IKIEMMBD_01660	1.11e-260	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
IKIEMMBD_01661	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IKIEMMBD_01662	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IKIEMMBD_01663	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
IKIEMMBD_01664	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IKIEMMBD_01665	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IKIEMMBD_01666	1.41e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IKIEMMBD_01667	5.18e-81	yqhP	-	-	-	-	-	-	-
IKIEMMBD_01668	5.16e-221	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
IKIEMMBD_01669	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
IKIEMMBD_01670	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
IKIEMMBD_01671	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IKIEMMBD_01672	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IKIEMMBD_01673	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
IKIEMMBD_01674	5.79e-217	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
IKIEMMBD_01675	1.63e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
IKIEMMBD_01676	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
IKIEMMBD_01677	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
IKIEMMBD_01678	3.11e-256	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
IKIEMMBD_01679	2.58e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
IKIEMMBD_01680	7.6e-149	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
IKIEMMBD_01681	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
IKIEMMBD_01682	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IKIEMMBD_01683	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IKIEMMBD_01684	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_01685	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IKIEMMBD_01686	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IKIEMMBD_01687	3.55e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IKIEMMBD_01688	3.12e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IKIEMMBD_01689	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IKIEMMBD_01690	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IKIEMMBD_01691	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
IKIEMMBD_01692	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IKIEMMBD_01693	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IKIEMMBD_01694	2.54e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
IKIEMMBD_01695	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IKIEMMBD_01697	1.63e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IKIEMMBD_01698	4.74e-37	-	-	-	-	-	-	-	-
IKIEMMBD_01699	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
IKIEMMBD_01700	8.31e-169	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IKIEMMBD_01701	7.76e-279	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IKIEMMBD_01702	5.91e-200	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
IKIEMMBD_01703	1.42e-267	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
IKIEMMBD_01704	6.46e-265	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IKIEMMBD_01705	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
IKIEMMBD_01706	7.23e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IKIEMMBD_01707	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
IKIEMMBD_01708	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
IKIEMMBD_01709	5e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
IKIEMMBD_01710	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IKIEMMBD_01711	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
IKIEMMBD_01712	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IKIEMMBD_01713	2.24e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IKIEMMBD_01714	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IKIEMMBD_01715	1.32e-288	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKIEMMBD_01716	6.12e-193	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
IKIEMMBD_01717	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_01718	4.23e-214	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IKIEMMBD_01719	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
IKIEMMBD_01720	4.11e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IKIEMMBD_01721	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IKIEMMBD_01722	5.2e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IKIEMMBD_01723	1.55e-224	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
IKIEMMBD_01724	2.41e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_01726	9.42e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
IKIEMMBD_01727	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IKIEMMBD_01728	2.14e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
IKIEMMBD_01729	5.08e-183	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
IKIEMMBD_01730	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKIEMMBD_01731	2.51e-32	yqzJ	-	-	-	-	-	-	-
IKIEMMBD_01732	1.57e-300	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKIEMMBD_01733	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IKIEMMBD_01734	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IKIEMMBD_01735	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IKIEMMBD_01736	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IKIEMMBD_01737	1.29e-186	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IKIEMMBD_01738	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IKIEMMBD_01739	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IKIEMMBD_01740	3.96e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IKIEMMBD_01741	3.66e-226	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IKIEMMBD_01742	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_01743	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
IKIEMMBD_01744	1.09e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IKIEMMBD_01745	7.72e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKIEMMBD_01747	2.85e-285	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
IKIEMMBD_01749	1.35e-302	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKIEMMBD_01750	2.66e-65	yqiX	-	-	S	-	-	-	YolD-like protein
IKIEMMBD_01751	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IKIEMMBD_01752	6.7e-73	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
IKIEMMBD_01753	1.87e-247	yqkA	-	-	K	-	-	-	GrpB protein
IKIEMMBD_01754	3.57e-72	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
IKIEMMBD_01755	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
IKIEMMBD_01756	5.8e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IKIEMMBD_01757	6.61e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
IKIEMMBD_01758	5.13e-215	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
IKIEMMBD_01759	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
IKIEMMBD_01760	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
IKIEMMBD_01761	4.16e-280	yqxK	-	-	L	-	-	-	DNA helicase
IKIEMMBD_01762	1.29e-76	ansR	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_01763	1.46e-237	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
IKIEMMBD_01764	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
IKIEMMBD_01765	8.88e-317	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IKIEMMBD_01766	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IKIEMMBD_01767	7.27e-42	yqkK	-	-	-	-	-	-	-
IKIEMMBD_01768	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IKIEMMBD_01769	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IKIEMMBD_01770	2.25e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
IKIEMMBD_01771	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
IKIEMMBD_01772	6.8e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IKIEMMBD_01773	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IKIEMMBD_01774	3.37e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IKIEMMBD_01775	3e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
IKIEMMBD_01776	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IKIEMMBD_01777	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKIEMMBD_01778	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
IKIEMMBD_01779	7.71e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
IKIEMMBD_01780	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
IKIEMMBD_01781	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
IKIEMMBD_01782	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IKIEMMBD_01783	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IKIEMMBD_01784	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
IKIEMMBD_01785	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IKIEMMBD_01786	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
IKIEMMBD_01787	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IKIEMMBD_01793	2.61e-34	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IKIEMMBD_01795	6.1e-11	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
IKIEMMBD_01796	3.82e-09	-	-	-	S	-	-	-	SNARE associated Golgi protein
IKIEMMBD_01798	1.28e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
IKIEMMBD_01799	3.39e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IKIEMMBD_01800	5.98e-72	ypuD	-	-	-	-	-	-	-
IKIEMMBD_01801	6.91e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IKIEMMBD_01802	1.24e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IKIEMMBD_01803	1.27e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IKIEMMBD_01804	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IKIEMMBD_01805	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKIEMMBD_01806	5.92e-119	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
IKIEMMBD_01807	9.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IKIEMMBD_01808	9.54e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IKIEMMBD_01809	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
IKIEMMBD_01810	6.81e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IKIEMMBD_01811	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
IKIEMMBD_01812	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
IKIEMMBD_01813	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IKIEMMBD_01814	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IKIEMMBD_01815	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
IKIEMMBD_01816	4.67e-279	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IKIEMMBD_01817	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_01818	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_01819	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_01820	6.68e-244	rsiX	-	-	-	-	-	-	-
IKIEMMBD_01821	4.79e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IKIEMMBD_01822	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IKIEMMBD_01823	3.59e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IKIEMMBD_01824	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
IKIEMMBD_01825	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
IKIEMMBD_01826	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IKIEMMBD_01827	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
IKIEMMBD_01828	8.61e-143	ypbE	-	-	M	-	-	-	Lysin motif
IKIEMMBD_01829	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
IKIEMMBD_01830	3.56e-187	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IKIEMMBD_01831	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IKIEMMBD_01832	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IKIEMMBD_01833	6.04e-223	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
IKIEMMBD_01834	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
IKIEMMBD_01835	6.93e-208	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
IKIEMMBD_01836	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
IKIEMMBD_01837	4.63e-144	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
IKIEMMBD_01838	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
IKIEMMBD_01839	1.73e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IKIEMMBD_01840	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IKIEMMBD_01841	5.43e-234	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IKIEMMBD_01842	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
IKIEMMBD_01843	1.11e-133	yphA	-	-	-	-	-	-	-
IKIEMMBD_01844	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
IKIEMMBD_01845	8.69e-40	ypzH	-	-	-	-	-	-	-
IKIEMMBD_01846	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IKIEMMBD_01847	2.57e-230	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IKIEMMBD_01848	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
IKIEMMBD_01849	4.31e-176	yphF	-	-	-	-	-	-	-
IKIEMMBD_01850	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IKIEMMBD_01851	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IKIEMMBD_01852	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IKIEMMBD_01853	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IKIEMMBD_01854	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IKIEMMBD_01855	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IKIEMMBD_01856	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IKIEMMBD_01857	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IKIEMMBD_01858	3.03e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
IKIEMMBD_01859	2.91e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IKIEMMBD_01860	1.11e-260	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IKIEMMBD_01861	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IKIEMMBD_01862	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IKIEMMBD_01863	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IKIEMMBD_01864	2.95e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IKIEMMBD_01865	1.57e-150	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
IKIEMMBD_01866	6.3e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IKIEMMBD_01867	3.82e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IKIEMMBD_01868	1.29e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IKIEMMBD_01869	1.71e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IKIEMMBD_01870	1.64e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IKIEMMBD_01871	8.74e-298	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
IKIEMMBD_01872	7.45e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
IKIEMMBD_01873	1.86e-98	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
IKIEMMBD_01874	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
IKIEMMBD_01875	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
IKIEMMBD_01876	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
IKIEMMBD_01877	1.27e-123	ypjA	-	-	S	-	-	-	membrane
IKIEMMBD_01878	2.79e-182	ypjB	-	-	S	-	-	-	sporulation protein
IKIEMMBD_01879	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IKIEMMBD_01880	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
IKIEMMBD_01881	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IKIEMMBD_01882	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
IKIEMMBD_01883	1.89e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
IKIEMMBD_01884	4.05e-266	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
IKIEMMBD_01885	3.7e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IKIEMMBD_01886	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IKIEMMBD_01887	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IKIEMMBD_01888	5.47e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IKIEMMBD_01889	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IKIEMMBD_01890	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IKIEMMBD_01891	6.21e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
IKIEMMBD_01892	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_01893	1.25e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IKIEMMBD_01894	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
IKIEMMBD_01895	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
IKIEMMBD_01896	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IKIEMMBD_01897	1.43e-121	ypoC	-	-	-	-	-	-	-
IKIEMMBD_01898	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IKIEMMBD_01899	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IKIEMMBD_01900	1.85e-240	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
IKIEMMBD_01903	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
IKIEMMBD_01904	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
IKIEMMBD_01905	4.14e-66	yppG	-	-	S	-	-	-	YppG-like protein
IKIEMMBD_01906	4.33e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IKIEMMBD_01907	5.3e-110	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
IKIEMMBD_01908	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IKIEMMBD_01909	2.41e-299	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
IKIEMMBD_01910	3.28e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IKIEMMBD_01911	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IKIEMMBD_01912	6.69e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IKIEMMBD_01914	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
IKIEMMBD_01915	3.12e-174	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_01916	2.08e-203	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IKIEMMBD_01917	1.29e-236	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
IKIEMMBD_01918	6.67e-236	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
IKIEMMBD_01919	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
IKIEMMBD_01920	5.8e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IKIEMMBD_01921	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IKIEMMBD_01922	3.88e-127	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IKIEMMBD_01923	3.51e-291	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IKIEMMBD_01924	4.01e-260	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
IKIEMMBD_01925	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
IKIEMMBD_01926	0.0	ypbR	-	-	S	-	-	-	Dynamin family
IKIEMMBD_01927	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
IKIEMMBD_01928	1.08e-11	-	-	-	-	-	-	-	-
IKIEMMBD_01929	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
IKIEMMBD_01930	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
IKIEMMBD_01931	1.27e-86	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
IKIEMMBD_01932	3.27e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IKIEMMBD_01933	2.31e-162	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
IKIEMMBD_01934	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
IKIEMMBD_01935	8.67e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
IKIEMMBD_01936	1.17e-22	degR	-	-	-	-	-	-	-
IKIEMMBD_01937	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IKIEMMBD_01938	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IKIEMMBD_01940	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IKIEMMBD_01941	2.58e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IKIEMMBD_01942	1.91e-137	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IKIEMMBD_01943	6.98e-205	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
IKIEMMBD_01944	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IKIEMMBD_01945	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
IKIEMMBD_01946	1.76e-186	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
IKIEMMBD_01947	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
IKIEMMBD_01948	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IKIEMMBD_01949	6.98e-201	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IKIEMMBD_01950	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IKIEMMBD_01951	8.12e-144	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IKIEMMBD_01952	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
IKIEMMBD_01953	8.1e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_01954	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IKIEMMBD_01955	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
IKIEMMBD_01956	1.48e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IKIEMMBD_01957	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IKIEMMBD_01958	1.95e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_01959	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
IKIEMMBD_01960	9.55e-288	mepA	-	-	V	-	-	-	MATE efflux family protein
IKIEMMBD_01961	2.39e-93	ypoP	-	-	K	-	-	-	transcriptional
IKIEMMBD_01962	8.41e-134	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IKIEMMBD_01963	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IKIEMMBD_01964	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IKIEMMBD_01965	7.73e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
IKIEMMBD_01966	6.67e-237	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
IKIEMMBD_01967	5.57e-86	cgeA	-	-	-	ko:K06319	-	ko00000	-
IKIEMMBD_01968	8.72e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
IKIEMMBD_01969	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
IKIEMMBD_01970	9.78e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
IKIEMMBD_01972	9.36e-317	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IKIEMMBD_01973	4.64e-159	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IKIEMMBD_01974	2.71e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IKIEMMBD_01975	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
IKIEMMBD_01976	1.24e-195	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
IKIEMMBD_01977	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
IKIEMMBD_01978	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
IKIEMMBD_01979	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IKIEMMBD_01980	1.29e-159	yodN	-	-	-	-	-	-	-
IKIEMMBD_01982	1.49e-33	yozD	-	-	S	-	-	-	YozD-like protein
IKIEMMBD_01983	1.64e-137	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IKIEMMBD_01984	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
IKIEMMBD_01985	2.08e-12	-	-	-	-	-	-	-	-
IKIEMMBD_01986	3.4e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IKIEMMBD_01987	7.71e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IKIEMMBD_01988	4.86e-41	yodI	-	-	-	-	-	-	-
IKIEMMBD_01989	3.69e-167	yodH	-	-	Q	-	-	-	Methyltransferase
IKIEMMBD_01990	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IKIEMMBD_01991	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKIEMMBD_01992	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IKIEMMBD_01993	1.18e-223	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IKIEMMBD_01994	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
IKIEMMBD_01995	1.11e-139	yodC	-	-	C	-	-	-	nitroreductase
IKIEMMBD_01996	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
IKIEMMBD_01997	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
IKIEMMBD_01998	1.08e-288	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IKIEMMBD_01999	1.95e-14	-	-	-	-	-	-	-	-
IKIEMMBD_02000	7.43e-107	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
IKIEMMBD_02001	1.35e-206	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
IKIEMMBD_02002	1.85e-58	-	-	-	-	-	-	-	-
IKIEMMBD_02003	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
IKIEMMBD_02004	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
IKIEMMBD_02005	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IKIEMMBD_02006	2.8e-311	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
IKIEMMBD_02008	3.54e-140	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IKIEMMBD_02009	1.61e-293	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
IKIEMMBD_02010	1.3e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IKIEMMBD_02011	7.31e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IKIEMMBD_02012	1.33e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
IKIEMMBD_02013	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
IKIEMMBD_02014	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IKIEMMBD_02015	2.59e-264	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IKIEMMBD_02016	3.31e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
IKIEMMBD_02017	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IKIEMMBD_02018	9.22e-210	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
IKIEMMBD_02019	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
IKIEMMBD_02020	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IKIEMMBD_02021	1.91e-42	yozC	-	-	-	-	-	-	-
IKIEMMBD_02022	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
IKIEMMBD_02023	1.83e-49	yocN	-	-	-	-	-	-	-
IKIEMMBD_02024	2.94e-55	yozN	-	-	-	-	-	-	-
IKIEMMBD_02025	4.47e-113	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IKIEMMBD_02026	2.02e-43	-	-	-	-	-	-	-	-
IKIEMMBD_02027	3.02e-70	yocL	-	-	-	-	-	-	-
IKIEMMBD_02028	4.07e-107	yocK	-	-	T	-	-	-	general stress protein
IKIEMMBD_02029	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IKIEMMBD_02030	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IKIEMMBD_02031	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
IKIEMMBD_02032	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKIEMMBD_02033	3.51e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_02034	3.28e-257	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
IKIEMMBD_02035	7.83e-240	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
IKIEMMBD_02036	1.8e-120	yocC	-	-	-	-	-	-	-
IKIEMMBD_02037	2.6e-185	-	-	-	-	-	-	-	-
IKIEMMBD_02038	3.27e-118	yozB	-	-	S	ko:K08976	-	ko00000	membrane
IKIEMMBD_02039	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IKIEMMBD_02040	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
IKIEMMBD_02041	3.01e-120	yobW	-	-	-	-	-	-	-
IKIEMMBD_02042	9.35e-226	yobV	-	-	K	-	-	-	WYL domain
IKIEMMBD_02043	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IKIEMMBD_02044	2.84e-166	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IKIEMMBD_02045	1.26e-126	yobS	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_02046	4.16e-180	-	-	-	J	-	-	-	FR47-like protein
IKIEMMBD_02047	3.03e-174	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IKIEMMBD_02048	8.66e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
IKIEMMBD_02049	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
IKIEMMBD_02050	2.8e-132	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
IKIEMMBD_02051	1.13e-20	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IKIEMMBD_02052	1.95e-26	-	-	-	-	-	-	-	-
IKIEMMBD_02054	7.88e-135	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IKIEMMBD_02056	1.1e-23	-	-	-	-	-	-	-	-
IKIEMMBD_02057	3.23e-86	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
IKIEMMBD_02058	5e-134	-	-	-	-	-	-	-	-
IKIEMMBD_02059	4.81e-152	-	-	-	O	-	-	-	Subtilase family
IKIEMMBD_02061	1.85e-49	-	-	-	-	-	-	-	-
IKIEMMBD_02062	1.03e-85	-	-	-	O	-	-	-	Torsin
IKIEMMBD_02064	1.56e-12	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IKIEMMBD_02070	7.35e-17	-	-	-	-	-	-	-	-
IKIEMMBD_02071	1.07e-156	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
IKIEMMBD_02072	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
IKIEMMBD_02075	4.72e-211	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
IKIEMMBD_02076	1.15e-145	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
IKIEMMBD_02077	5.63e-102	yoaW	-	-	-	-	-	-	-
IKIEMMBD_02078	1.06e-200	yoaV	-	-	EG	-	-	-	EamA-like transporter family
IKIEMMBD_02079	1.11e-201	yoaU	-	-	K	-	-	-	LysR substrate binding domain
IKIEMMBD_02080	5.46e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
IKIEMMBD_02081	7.38e-50	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_02082	1.31e-97	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
IKIEMMBD_02083	1.73e-216	yoaR	-	-	V	-	-	-	vancomycin resistance protein
IKIEMMBD_02084	9.96e-109	-	-	-	-	-	-	-	-
IKIEMMBD_02085	1.23e-86	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
IKIEMMBD_02086	1.11e-182	yoaP	-	-	K	-	-	-	YoaP-like
IKIEMMBD_02088	1.47e-291	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IKIEMMBD_02091	1.4e-168	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
IKIEMMBD_02092	3.38e-251	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
IKIEMMBD_02093	7.3e-145	yoaK	-	-	S	-	-	-	Membrane
IKIEMMBD_02094	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
IKIEMMBD_02095	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
IKIEMMBD_02096	1.68e-291	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
IKIEMMBD_02097	4.77e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
IKIEMMBD_02098	1.17e-12	-	-	-	-	-	-	-	-
IKIEMMBD_02099	1.99e-114	degA	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_02100	3.73e-193	-	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
IKIEMMBD_02101	3.41e-259	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
IKIEMMBD_02102	5.83e-216	-	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IKIEMMBD_02103	3.48e-43	yoaF	-	-	-	-	-	-	-
IKIEMMBD_02104	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IKIEMMBD_02105	5.57e-233	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IKIEMMBD_02106	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IKIEMMBD_02107	4.51e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
IKIEMMBD_02108	7.89e-160	-	3.1.1.3	-	I	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	Lipase (class 3)
IKIEMMBD_02109	4.19e-301	-	-	-	S	-	-	-	Arylsulfotransferase (ASST)
IKIEMMBD_02110	2.91e-116	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IKIEMMBD_02111	5.65e-161	yoxB	-	-	-	-	-	-	-
IKIEMMBD_02112	1.7e-54	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
IKIEMMBD_02113	9.27e-159	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_02114	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IKIEMMBD_02115	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IKIEMMBD_02116	3.86e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IKIEMMBD_02117	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_02118	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
IKIEMMBD_02119	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IKIEMMBD_02120	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IKIEMMBD_02121	4.34e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_02122	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IKIEMMBD_02123	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
IKIEMMBD_02124	1.14e-124	-	-	-	L	-	-	-	Integrase
IKIEMMBD_02126	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
IKIEMMBD_02127	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
IKIEMMBD_02128	4.72e-241	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IKIEMMBD_02129	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IKIEMMBD_02130	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_02131	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_02132	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_02133	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_02134	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
IKIEMMBD_02135	2.48e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IKIEMMBD_02136	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
IKIEMMBD_02137	6.59e-51	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
IKIEMMBD_02138	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IKIEMMBD_02139	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IKIEMMBD_02140	1.91e-314	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
IKIEMMBD_02141	1.23e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
IKIEMMBD_02142	2.86e-213	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
IKIEMMBD_02143	6.03e-175	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
IKIEMMBD_02144	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IKIEMMBD_02145	2.47e-294	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
IKIEMMBD_02146	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
IKIEMMBD_02147	5.53e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IKIEMMBD_02148	1.42e-102	yngA	-	-	S	-	-	-	membrane
IKIEMMBD_02149	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IKIEMMBD_02150	9.85e-317	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
IKIEMMBD_02152	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
IKIEMMBD_02153	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IKIEMMBD_02154	1.06e-75	ynfC	-	-	-	-	-	-	-
IKIEMMBD_02155	1.82e-18	-	-	-	-	-	-	-	-
IKIEMMBD_02156	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IKIEMMBD_02157	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IKIEMMBD_02158	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
IKIEMMBD_02159	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IKIEMMBD_02160	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IKIEMMBD_02161	1.63e-71	yneQ	-	-	-	-	-	-	-
IKIEMMBD_02162	1.4e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IKIEMMBD_02163	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
IKIEMMBD_02165	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
IKIEMMBD_02166	2.53e-118	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IKIEMMBD_02167	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IKIEMMBD_02168	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
IKIEMMBD_02169	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
IKIEMMBD_02170	2.35e-84	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
IKIEMMBD_02171	1.14e-96	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
IKIEMMBD_02172	7.21e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
IKIEMMBD_02173	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
IKIEMMBD_02174	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
IKIEMMBD_02175	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IKIEMMBD_02176	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IKIEMMBD_02177	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
IKIEMMBD_02178	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IKIEMMBD_02179	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
IKIEMMBD_02180	3.8e-143	yneB	-	-	L	-	-	-	resolvase
IKIEMMBD_02181	2.44e-64	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IKIEMMBD_02182	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IKIEMMBD_02183	4.44e-104	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IKIEMMBD_02184	1.32e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IKIEMMBD_02185	8e-176	yndL	-	-	S	-	-	-	Replication protein
IKIEMMBD_02187	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
IKIEMMBD_02188	2.44e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
IKIEMMBD_02189	2.52e-196	yndG	-	-	S	-	-	-	DoxX-like family
IKIEMMBD_02190	5.57e-151	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IKIEMMBD_02191	2.94e-96	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IKIEMMBD_02192	1.95e-250	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
IKIEMMBD_02193	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IKIEMMBD_02196	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
IKIEMMBD_02197	8.92e-96	-	-	-	-	-	-	-	-
IKIEMMBD_02198	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
IKIEMMBD_02201	7.38e-159	-	-	-	S	-	-	-	Domain of unknown function, YrpD
IKIEMMBD_02202	1.86e-208	-	-	-	S	-	-	-	Thymidylate synthase
IKIEMMBD_02205	7.54e-22	-	-	-	-	-	-	-	-
IKIEMMBD_02206	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
IKIEMMBD_02207	9.48e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
IKIEMMBD_02208	1.77e-280	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IKIEMMBD_02209	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IKIEMMBD_02210	2.51e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
IKIEMMBD_02211	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
IKIEMMBD_02212	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IKIEMMBD_02213	6.82e-273	xylR	-	-	GK	-	-	-	ROK family
IKIEMMBD_02214	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IKIEMMBD_02215	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IKIEMMBD_02216	4.15e-108	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
IKIEMMBD_02219	1.23e-138	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IKIEMMBD_02220	5.85e-32	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IKIEMMBD_02222	1.85e-92	-	-	-	S	-	-	-	CAAX protease self-immunity
IKIEMMBD_02224	4.28e-128	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IKIEMMBD_02225	1.23e-180	ynaC	-	-	-	-	-	-	-
IKIEMMBD_02226	2.05e-116	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
IKIEMMBD_02227	2.39e-50	-	-	-	-	-	-	-	-
IKIEMMBD_02229	3.06e-14	-	-	-	-	-	-	-	-
IKIEMMBD_02230	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IKIEMMBD_02231	2.85e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
IKIEMMBD_02232	1.67e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IKIEMMBD_02233	1.05e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IKIEMMBD_02234	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
IKIEMMBD_02235	8.15e-150	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IKIEMMBD_02236	2.24e-141	-	-	-	-	-	-	-	-
IKIEMMBD_02237	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKIEMMBD_02238	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKIEMMBD_02239	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IKIEMMBD_02240	1.2e-30	ymzA	-	-	-	-	-	-	-
IKIEMMBD_02241	1.63e-31	-	-	-	-	-	-	-	-
IKIEMMBD_02242	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IKIEMMBD_02243	1.13e-222	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IKIEMMBD_02244	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
IKIEMMBD_02246	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IKIEMMBD_02247	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
IKIEMMBD_02248	6.98e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
IKIEMMBD_02249	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
IKIEMMBD_02251	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
IKIEMMBD_02252	1.88e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IKIEMMBD_02253	8.03e-81	ymzB	-	-	-	-	-	-	-
IKIEMMBD_02254	1.18e-295	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IKIEMMBD_02255	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
IKIEMMBD_02256	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
IKIEMMBD_02257	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
IKIEMMBD_02258	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
IKIEMMBD_02259	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
IKIEMMBD_02260	3.15e-176	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
IKIEMMBD_02261	5.01e-184	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
IKIEMMBD_02262	1.61e-312	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
IKIEMMBD_02263	7.23e-302	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IKIEMMBD_02264	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
IKIEMMBD_02265	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IKIEMMBD_02266	1.4e-237	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
IKIEMMBD_02268	2.17e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IKIEMMBD_02270	4.02e-167	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
IKIEMMBD_02271	3.43e-140	pksA	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_02272	9.3e-126	ymcC	-	-	S	-	-	-	Membrane
IKIEMMBD_02274	3.04e-88	-	-	-	S	-	-	-	Regulatory protein YrvL
IKIEMMBD_02275	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IKIEMMBD_02276	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IKIEMMBD_02277	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
IKIEMMBD_02278	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
IKIEMMBD_02279	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IKIEMMBD_02280	5.89e-278	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IKIEMMBD_02281	2.04e-253	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IKIEMMBD_02282	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
IKIEMMBD_02283	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
IKIEMMBD_02284	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IKIEMMBD_02285	4e-280	pbpX	-	-	V	-	-	-	Beta-lactamase
IKIEMMBD_02286	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IKIEMMBD_02287	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IKIEMMBD_02288	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IKIEMMBD_02289	3.05e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
IKIEMMBD_02290	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
IKIEMMBD_02291	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IKIEMMBD_02292	1.49e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IKIEMMBD_02293	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
IKIEMMBD_02294	2.23e-297	albE	-	-	S	-	-	-	Peptidase M16
IKIEMMBD_02295	2.82e-263	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_02296	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_02297	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IKIEMMBD_02298	8.23e-43	-	-	-	S	-	-	-	YlzJ-like protein
IKIEMMBD_02299	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
IKIEMMBD_02300	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IKIEMMBD_02301	6.39e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IKIEMMBD_02302	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IKIEMMBD_02303	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IKIEMMBD_02304	9.94e-142	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IKIEMMBD_02305	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
IKIEMMBD_02306	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
IKIEMMBD_02307	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
IKIEMMBD_02308	2.15e-234	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
IKIEMMBD_02309	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IKIEMMBD_02310	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IKIEMMBD_02311	1.34e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IKIEMMBD_02312	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IKIEMMBD_02313	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IKIEMMBD_02314	7.83e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
IKIEMMBD_02315	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IKIEMMBD_02316	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
IKIEMMBD_02317	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
IKIEMMBD_02318	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IKIEMMBD_02319	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IKIEMMBD_02320	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IKIEMMBD_02321	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IKIEMMBD_02322	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IKIEMMBD_02323	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IKIEMMBD_02324	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IKIEMMBD_02325	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IKIEMMBD_02326	5.55e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IKIEMMBD_02327	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IKIEMMBD_02328	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IKIEMMBD_02329	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IKIEMMBD_02330	1.34e-98	ylxL	-	-	-	-	-	-	-
IKIEMMBD_02331	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKIEMMBD_02332	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IKIEMMBD_02333	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IKIEMMBD_02334	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
IKIEMMBD_02335	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
IKIEMMBD_02336	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IKIEMMBD_02337	6.33e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
IKIEMMBD_02338	3.27e-255	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
IKIEMMBD_02339	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IKIEMMBD_02340	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IKIEMMBD_02341	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
IKIEMMBD_02342	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
IKIEMMBD_02343	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
IKIEMMBD_02344	5.54e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
IKIEMMBD_02345	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
IKIEMMBD_02346	2.28e-252	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IKIEMMBD_02347	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IKIEMMBD_02348	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
IKIEMMBD_02349	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
IKIEMMBD_02350	3.99e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
IKIEMMBD_02351	4.26e-310	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
IKIEMMBD_02352	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
IKIEMMBD_02353	7.27e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
IKIEMMBD_02354	1.22e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IKIEMMBD_02355	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
IKIEMMBD_02356	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IKIEMMBD_02357	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
IKIEMMBD_02358	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
IKIEMMBD_02359	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
IKIEMMBD_02360	9.37e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IKIEMMBD_02361	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IKIEMMBD_02362	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IKIEMMBD_02363	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IKIEMMBD_02364	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
IKIEMMBD_02365	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IKIEMMBD_02366	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IKIEMMBD_02367	2.98e-214	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
IKIEMMBD_02368	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IKIEMMBD_02369	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IKIEMMBD_02370	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
IKIEMMBD_02371	0.0	ylqG	-	-	-	-	-	-	-
IKIEMMBD_02372	1.18e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IKIEMMBD_02373	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IKIEMMBD_02374	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IKIEMMBD_02375	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IKIEMMBD_02376	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IKIEMMBD_02377	3.98e-79	ylqD	-	-	S	-	-	-	YlqD protein
IKIEMMBD_02378	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IKIEMMBD_02379	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IKIEMMBD_02380	3.95e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IKIEMMBD_02381	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IKIEMMBD_02382	1.67e-114	-	-	-	-	-	-	-	-
IKIEMMBD_02383	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IKIEMMBD_02384	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IKIEMMBD_02385	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IKIEMMBD_02386	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IKIEMMBD_02387	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IKIEMMBD_02388	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IKIEMMBD_02389	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IKIEMMBD_02390	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IKIEMMBD_02391	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IKIEMMBD_02392	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IKIEMMBD_02393	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IKIEMMBD_02394	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
IKIEMMBD_02395	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02396	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IKIEMMBD_02397	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IKIEMMBD_02398	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IKIEMMBD_02399	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IKIEMMBD_02400	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IKIEMMBD_02401	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IKIEMMBD_02402	6.19e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IKIEMMBD_02403	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IKIEMMBD_02404	4.98e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IKIEMMBD_02405	4.8e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IKIEMMBD_02406	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IKIEMMBD_02407	5.13e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IKIEMMBD_02408	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IKIEMMBD_02409	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IKIEMMBD_02410	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
IKIEMMBD_02411	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
IKIEMMBD_02412	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
IKIEMMBD_02413	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IKIEMMBD_02414	5.37e-107	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
IKIEMMBD_02415	5.9e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
IKIEMMBD_02416	3.56e-186	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IKIEMMBD_02417	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IKIEMMBD_02418	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IKIEMMBD_02419	2.98e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
IKIEMMBD_02420	1.46e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IKIEMMBD_02421	2.57e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IKIEMMBD_02422	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IKIEMMBD_02423	3e-221	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IKIEMMBD_02424	4.31e-182	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IKIEMMBD_02425	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
IKIEMMBD_02426	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IKIEMMBD_02427	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IKIEMMBD_02428	7.29e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IKIEMMBD_02429	1.3e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
IKIEMMBD_02430	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IKIEMMBD_02431	2.38e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IKIEMMBD_02432	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IKIEMMBD_02433	1.58e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IKIEMMBD_02434	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IKIEMMBD_02435	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
IKIEMMBD_02436	2.12e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
IKIEMMBD_02437	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
IKIEMMBD_02438	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IKIEMMBD_02439	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IKIEMMBD_02440	3.58e-201	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
IKIEMMBD_02441	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
IKIEMMBD_02442	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
IKIEMMBD_02443	1.57e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IKIEMMBD_02444	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKIEMMBD_02445	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKIEMMBD_02446	1.06e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IKIEMMBD_02447	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
IKIEMMBD_02448	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IKIEMMBD_02449	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IKIEMMBD_02450	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
IKIEMMBD_02451	2.13e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02452	1.35e-143	ylxW	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02453	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IKIEMMBD_02454	2.16e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
IKIEMMBD_02455	3.84e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IKIEMMBD_02456	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IKIEMMBD_02457	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IKIEMMBD_02458	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IKIEMMBD_02459	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IKIEMMBD_02460	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
IKIEMMBD_02461	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IKIEMMBD_02462	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
IKIEMMBD_02463	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IKIEMMBD_02464	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IKIEMMBD_02465	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IKIEMMBD_02466	9.23e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IKIEMMBD_02467	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
IKIEMMBD_02468	1.35e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IKIEMMBD_02469	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IKIEMMBD_02470	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
IKIEMMBD_02472	8.66e-294	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IKIEMMBD_02473	3.18e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IKIEMMBD_02474	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IKIEMMBD_02475	5.5e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
IKIEMMBD_02476	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IKIEMMBD_02477	3.51e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
IKIEMMBD_02478	5.1e-51	ylbG	-	-	S	-	-	-	UPF0298 protein
IKIEMMBD_02479	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
IKIEMMBD_02480	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
IKIEMMBD_02481	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
IKIEMMBD_02482	1.53e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
IKIEMMBD_02483	9.77e-64	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
IKIEMMBD_02484	2e-15	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
IKIEMMBD_02485	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
IKIEMMBD_02486	8.54e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
IKIEMMBD_02487	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IKIEMMBD_02488	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IKIEMMBD_02489	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IKIEMMBD_02490	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IKIEMMBD_02491	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IKIEMMBD_02492	2e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IKIEMMBD_02493	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IKIEMMBD_02494	2.16e-265	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IKIEMMBD_02495	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
IKIEMMBD_02496	1e-218	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IKIEMMBD_02497	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IKIEMMBD_02498	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
IKIEMMBD_02499	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IKIEMMBD_02500	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02501	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
IKIEMMBD_02502	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IKIEMMBD_02503	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
IKIEMMBD_02504	4.02e-56	ylaE	-	-	-	-	-	-	-
IKIEMMBD_02506	3.56e-115	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_02507	1.44e-56	ylaB	-	-	-	-	-	-	-
IKIEMMBD_02508	0.0	ylaA	-	-	-	-	-	-	-
IKIEMMBD_02509	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IKIEMMBD_02510	2.88e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IKIEMMBD_02511	1.48e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
IKIEMMBD_02512	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
IKIEMMBD_02513	4.48e-35	ykzI	-	-	-	-	-	-	-
IKIEMMBD_02514	5.28e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IKIEMMBD_02515	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IKIEMMBD_02516	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
IKIEMMBD_02517	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
IKIEMMBD_02518	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IKIEMMBD_02519	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKIEMMBD_02520	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IKIEMMBD_02521	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IKIEMMBD_02522	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
IKIEMMBD_02523	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IKIEMMBD_02524	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IKIEMMBD_02525	1.18e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
IKIEMMBD_02526	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IKIEMMBD_02527	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IKIEMMBD_02528	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IKIEMMBD_02529	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IKIEMMBD_02530	1.45e-199	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
IKIEMMBD_02531	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IKIEMMBD_02532	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
IKIEMMBD_02533	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
IKIEMMBD_02534	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
IKIEMMBD_02535	4.19e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
IKIEMMBD_02536	4.75e-214	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IKIEMMBD_02537	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IKIEMMBD_02538	5.43e-52	ykoA	-	-	-	-	-	-	-
IKIEMMBD_02539	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IKIEMMBD_02540	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IKIEMMBD_02541	8.21e-215	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
IKIEMMBD_02542	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_02543	3.33e-266	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IKIEMMBD_02544	3.53e-159	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_02545	2.34e-233	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IKIEMMBD_02546	5.97e-147	yknW	-	-	S	-	-	-	Yip1 domain
IKIEMMBD_02547	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IKIEMMBD_02548	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IKIEMMBD_02549	6.92e-45	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IKIEMMBD_02550	3.83e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
IKIEMMBD_02551	4.89e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
IKIEMMBD_02552	4.29e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
IKIEMMBD_02553	7.59e-245	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IKIEMMBD_02554	1.86e-141	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IKIEMMBD_02555	5.72e-199	yknT	-	-	-	ko:K06437	-	ko00000	-
IKIEMMBD_02556	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
IKIEMMBD_02557	6.25e-106	ykuV	-	-	CO	-	-	-	thiol-disulfide
IKIEMMBD_02558	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
IKIEMMBD_02559	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
IKIEMMBD_02560	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
IKIEMMBD_02561	7.99e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IKIEMMBD_02562	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IKIEMMBD_02563	1.3e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IKIEMMBD_02564	2.12e-223	ykuO	-	-	-	-	-	-	-
IKIEMMBD_02565	7.72e-114	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
IKIEMMBD_02566	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_02567	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
IKIEMMBD_02568	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
IKIEMMBD_02569	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
IKIEMMBD_02570	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02571	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
IKIEMMBD_02572	2.13e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_02573	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
IKIEMMBD_02574	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02575	3.62e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_02576	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
IKIEMMBD_02577	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
IKIEMMBD_02578	1.05e-22	-	-	-	-	-	-	-	-
IKIEMMBD_02579	1.78e-284	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IKIEMMBD_02580	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_02581	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IKIEMMBD_02582	5.36e-172	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
IKIEMMBD_02583	5.71e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IKIEMMBD_02584	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IKIEMMBD_02585	1.4e-163	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKIEMMBD_02586	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
IKIEMMBD_02587	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_02588	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IKIEMMBD_02589	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
IKIEMMBD_02590	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_02591	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
IKIEMMBD_02592	2.69e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_02593	1.11e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IKIEMMBD_02594	3.99e-09	-	-	-	-	-	-	-	-
IKIEMMBD_02595	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IKIEMMBD_02596	5.57e-115	stoA	-	-	CO	-	-	-	thiol-disulfide
IKIEMMBD_02597	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKIEMMBD_02598	5.26e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
IKIEMMBD_02599	2.6e-39	-	-	-	-	-	-	-	-
IKIEMMBD_02600	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02601	8.95e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
IKIEMMBD_02602	3.02e-205	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
IKIEMMBD_02603	7.56e-48	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
IKIEMMBD_02604	1.01e-270	-	-	-	M	-	-	-	Glycosyl transferases group 1
IKIEMMBD_02605	2.2e-171	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IKIEMMBD_02606	2.8e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_02607	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IKIEMMBD_02608	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IKIEMMBD_02609	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
IKIEMMBD_02610	6.42e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IKIEMMBD_02611	7.06e-229	ykvI	-	-	S	-	-	-	membrane
IKIEMMBD_02612	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IKIEMMBD_02613	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IKIEMMBD_02614	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IKIEMMBD_02615	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IKIEMMBD_02616	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IKIEMMBD_02617	2.38e-94	eag	-	-	-	-	-	-	-
IKIEMMBD_02619	3.6e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
IKIEMMBD_02620	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IKIEMMBD_02621	7.5e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IKIEMMBD_02622	1.77e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IKIEMMBD_02623	1.09e-291	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IKIEMMBD_02624	6.56e-294	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IKIEMMBD_02625	5.71e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IKIEMMBD_02626	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IKIEMMBD_02627	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IKIEMMBD_02629	2.27e-114	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IKIEMMBD_02630	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_02631	1.12e-242	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
IKIEMMBD_02632	2.94e-27	ykzE	-	-	-	-	-	-	-
IKIEMMBD_02634	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
IKIEMMBD_02635	6.57e-198	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IKIEMMBD_02636	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
IKIEMMBD_02637	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
IKIEMMBD_02638	1.41e-199	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
IKIEMMBD_02639	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKIEMMBD_02640	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IKIEMMBD_02641	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
IKIEMMBD_02642	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
IKIEMMBD_02643	2.49e-77	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
IKIEMMBD_02644	1.25e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IKIEMMBD_02645	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
IKIEMMBD_02646	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
IKIEMMBD_02647	0.0	ykoS	-	-	-	-	-	-	-
IKIEMMBD_02648	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IKIEMMBD_02649	1.44e-128	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
IKIEMMBD_02650	1.33e-278	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IKIEMMBD_02651	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IKIEMMBD_02652	2.51e-35	ykoL	-	-	-	-	-	-	-
IKIEMMBD_02653	3.3e-25	-	-	-	-	-	-	-	-
IKIEMMBD_02654	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
IKIEMMBD_02655	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
IKIEMMBD_02657	1.45e-08	-	-	-	-	-	-	-	-
IKIEMMBD_02658	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IKIEMMBD_02659	5.55e-145	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IKIEMMBD_02660	2.46e-306	ykoH	-	-	T	-	-	-	Histidine kinase
IKIEMMBD_02661	3.03e-159	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_02662	9.94e-142	ykoF	-	-	S	-	-	-	YKOF-related Family
IKIEMMBD_02663	6.62e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IKIEMMBD_02664	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_02665	3.12e-174	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IKIEMMBD_02666	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IKIEMMBD_02667	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IKIEMMBD_02668	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IKIEMMBD_02669	4.76e-128	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IKIEMMBD_02670	8.05e-106	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
IKIEMMBD_02671	2.21e-115	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IKIEMMBD_02672	1.72e-90	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IKIEMMBD_02673	1.08e-315	-	-	-	Q	-	-	-	Beta-ketoacyl synthase
IKIEMMBD_02674	4.97e-113	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	PFAM Acyl transferase
IKIEMMBD_02675	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
IKIEMMBD_02676	7.85e-312	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
IKIEMMBD_02677	0.0	-	-	-	Q	ko:K16123,ko:K16124	ko01054,map01054	ko00000,ko00001,ko01008	Non-ribosomal peptide synthetase modules and related proteins
IKIEMMBD_02678	7.13e-62	nrsA	-	-	Q	-	-	-	Thioesterase domain
IKIEMMBD_02679	8.31e-151	-	-	-	Q	-	-	-	cytochrome P450
IKIEMMBD_02680	7.64e-28	-	-	-	M	-	-	-	Glycosyl transferase family 2
IKIEMMBD_02681	6.71e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IKIEMMBD_02682	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
IKIEMMBD_02683	1.39e-92	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IKIEMMBD_02684	3.38e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IKIEMMBD_02685	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IKIEMMBD_02686	9.63e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IKIEMMBD_02687	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IKIEMMBD_02688	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IKIEMMBD_02689	2.08e-127	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IKIEMMBD_02690	6.41e-102	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
IKIEMMBD_02691	6.55e-166	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IKIEMMBD_02692	3.55e-14	-	-	-	-	-	-	-	-
IKIEMMBD_02693	5.35e-289	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IKIEMMBD_02694	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
IKIEMMBD_02695	2.08e-204	ykgA	-	-	E	-	-	-	Amidinotransferase
IKIEMMBD_02696	2.22e-258	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
IKIEMMBD_02697	4.88e-236	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IKIEMMBD_02698	2e-207	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IKIEMMBD_02699	1.89e-254	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IKIEMMBD_02700	6.49e-223	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
IKIEMMBD_02702	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IKIEMMBD_02703	1.64e-237	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IKIEMMBD_02704	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKIEMMBD_02705	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKIEMMBD_02706	1.15e-195	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
IKIEMMBD_02707	6.73e-178	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
IKIEMMBD_02708	8.43e-285	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IKIEMMBD_02710	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IKIEMMBD_02711	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IKIEMMBD_02712	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IKIEMMBD_02713	3.66e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IKIEMMBD_02714	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
IKIEMMBD_02715	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
IKIEMMBD_02716	1.97e-174	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
IKIEMMBD_02717	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
IKIEMMBD_02719	3.2e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IKIEMMBD_02720	3.87e-51	xhlB	-	-	S	-	-	-	SPP1 phage holin
IKIEMMBD_02721	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
IKIEMMBD_02722	2.21e-193	xepA	-	-	-	-	-	-	-
IKIEMMBD_02723	2.68e-32	xkdX	-	-	-	-	-	-	-
IKIEMMBD_02724	1.56e-60	xkdW	-	-	S	-	-	-	XkdW protein
IKIEMMBD_02725	0.0	-	-	-	-	-	-	-	-
IKIEMMBD_02726	4.43e-56	-	-	-	-	-	-	-	-
IKIEMMBD_02727	6.51e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IKIEMMBD_02728	4.2e-242	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IKIEMMBD_02729	1.33e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IKIEMMBD_02730	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
IKIEMMBD_02731	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
IKIEMMBD_02732	1.77e-158	xkdP	-	-	S	-	-	-	Lysin motif
IKIEMMBD_02733	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
IKIEMMBD_02734	3.34e-101	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
IKIEMMBD_02735	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
IKIEMMBD_02736	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
IKIEMMBD_02737	9.26e-98	xkdJ	-	-	-	-	-	-	-
IKIEMMBD_02738	1.96e-113	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IKIEMMBD_02739	1.23e-84	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
IKIEMMBD_02740	9.07e-80	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
IKIEMMBD_02741	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
IKIEMMBD_02742	2.71e-174	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
IKIEMMBD_02743	0.0	yqbA	-	-	S	-	-	-	portal protein
IKIEMMBD_02744	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
IKIEMMBD_02745	1.13e-177	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
IKIEMMBD_02746	3.31e-109	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IKIEMMBD_02750	3.55e-151	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
IKIEMMBD_02751	3.07e-202	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
IKIEMMBD_02753	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IKIEMMBD_02754	1.79e-143	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IKIEMMBD_02755	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
IKIEMMBD_02756	5.99e-143	yjqB	-	-	S	-	-	-	Pfam:DUF867
IKIEMMBD_02757	3.87e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
IKIEMMBD_02758	2.65e-218	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IKIEMMBD_02759	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
IKIEMMBD_02761	2.87e-270	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IKIEMMBD_02762	6.08e-314	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
IKIEMMBD_02763	3.55e-101	yjoA	-	-	S	-	-	-	DinB family
IKIEMMBD_02764	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IKIEMMBD_02765	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IKIEMMBD_02766	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
IKIEMMBD_02767	9.87e-238	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IKIEMMBD_02768	1.86e-287	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
IKIEMMBD_02769	1.34e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IKIEMMBD_02770	2.76e-273	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IKIEMMBD_02771	6.98e-241	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
IKIEMMBD_02772	1.2e-240	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
IKIEMMBD_02773	7.52e-315	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
IKIEMMBD_02774	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IKIEMMBD_02775	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IKIEMMBD_02776	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IKIEMMBD_02777	5.79e-117	yjlB	-	-	S	-	-	-	Cupin domain
IKIEMMBD_02778	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
IKIEMMBD_02779	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IKIEMMBD_02780	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
IKIEMMBD_02781	4.82e-186	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IKIEMMBD_02782	1.11e-41	-	-	-	-	-	-	-	-
IKIEMMBD_02783	4.84e-277	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IKIEMMBD_02784	1.85e-283	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IKIEMMBD_02786	2.61e-147	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IKIEMMBD_02788	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IKIEMMBD_02789	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IKIEMMBD_02790	4.08e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
IKIEMMBD_02791	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
IKIEMMBD_02792	7.02e-214	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
IKIEMMBD_02793	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
IKIEMMBD_02794	5.02e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
IKIEMMBD_02795	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
IKIEMMBD_02797	1.46e-221	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IKIEMMBD_02798	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
IKIEMMBD_02799	5.97e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
IKIEMMBD_02800	2.89e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IKIEMMBD_02802	3.61e-117	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IKIEMMBD_02803	5.34e-75	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
IKIEMMBD_02804	1.03e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IKIEMMBD_02805	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_02806	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
IKIEMMBD_02807	0.000141	-	-	-	-	-	-	-	-
IKIEMMBD_02808	2.81e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IKIEMMBD_02809	1.27e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IKIEMMBD_02810	8.3e-156	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IKIEMMBD_02814	9.03e-305	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
IKIEMMBD_02815	3.27e-41	-	-	-	-	-	-	-	-
IKIEMMBD_02816	2.03e-43	-	-	-	-	-	-	-	-
IKIEMMBD_02817	2.37e-19	-	-	-	-	-	-	-	-
IKIEMMBD_02819	4.27e-273	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
IKIEMMBD_02820	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
IKIEMMBD_02821	1.06e-279	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IKIEMMBD_02822	9.39e-272	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IKIEMMBD_02823	1.06e-174	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
IKIEMMBD_02824	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
IKIEMMBD_02825	2.22e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKIEMMBD_02826	6.31e-51	-	-	-	-	-	-	-	-
IKIEMMBD_02827	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IKIEMMBD_02828	1.55e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
IKIEMMBD_02831	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IKIEMMBD_02832	2.34e-66	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
IKIEMMBD_02833	9.3e-32	cotW	-	-	-	ko:K06341	-	ko00000	-
IKIEMMBD_02834	1.23e-95	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
IKIEMMBD_02835	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
IKIEMMBD_02836	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
IKIEMMBD_02837	3.63e-104	yjbX	-	-	S	-	-	-	Spore coat protein
IKIEMMBD_02838	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IKIEMMBD_02839	3.98e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IKIEMMBD_02840	7.21e-237	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IKIEMMBD_02841	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IKIEMMBD_02842	1.8e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
IKIEMMBD_02843	6.31e-275	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
IKIEMMBD_02844	5.7e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
IKIEMMBD_02845	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IKIEMMBD_02846	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IKIEMMBD_02847	8.09e-181	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IKIEMMBD_02848	1.49e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IKIEMMBD_02849	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IKIEMMBD_02850	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
IKIEMMBD_02851	3.77e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
IKIEMMBD_02852	7.32e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02853	2.94e-128	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IKIEMMBD_02854	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
IKIEMMBD_02855	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IKIEMMBD_02857	2.68e-28	-	-	-	-	-	-	-	-
IKIEMMBD_02858	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IKIEMMBD_02859	1.03e-280	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IKIEMMBD_02860	6.34e-147	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IKIEMMBD_02861	2.03e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
IKIEMMBD_02862	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IKIEMMBD_02863	2.65e-133	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKIEMMBD_02864	1.18e-267	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IKIEMMBD_02865	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IKIEMMBD_02866	3.22e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IKIEMMBD_02867	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKIEMMBD_02868	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKIEMMBD_02869	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IKIEMMBD_02870	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
IKIEMMBD_02871	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
IKIEMMBD_02872	3.49e-196	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKIEMMBD_02873	6.73e-216	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKIEMMBD_02874	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
IKIEMMBD_02875	3.43e-236	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IKIEMMBD_02876	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IKIEMMBD_02877	1.06e-189	yjaZ	-	-	O	-	-	-	Zn-dependent protease
IKIEMMBD_02878	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IKIEMMBD_02879	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IKIEMMBD_02880	2.67e-38	yjzB	-	-	-	-	-	-	-
IKIEMMBD_02881	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
IKIEMMBD_02882	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
IKIEMMBD_02883	3.01e-131	yjaV	-	-	-	-	-	-	-
IKIEMMBD_02884	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
IKIEMMBD_02885	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IKIEMMBD_02886	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
IKIEMMBD_02887	2.47e-224	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IKIEMMBD_02888	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
IKIEMMBD_02889	2.33e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IKIEMMBD_02890	3.81e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
IKIEMMBD_02891	7.35e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IKIEMMBD_02892	8.64e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IKIEMMBD_02893	7.11e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IKIEMMBD_02894	8.57e-112	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
IKIEMMBD_02895	6.07e-127	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
IKIEMMBD_02896	2e-191	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
IKIEMMBD_02897	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
IKIEMMBD_02898	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
IKIEMMBD_02899	4.85e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IKIEMMBD_02900	1.52e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IKIEMMBD_02901	1.92e-08	-	-	-	-	-	-	-	-
IKIEMMBD_02902	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
IKIEMMBD_02903	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
IKIEMMBD_02904	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IKIEMMBD_02905	1.07e-200	yitS	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_02906	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IKIEMMBD_02907	6.52e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
IKIEMMBD_02908	1.06e-120	-	-	-	-	-	-	-	-
IKIEMMBD_02909	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IKIEMMBD_02910	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IKIEMMBD_02911	1.17e-217	-	-	-	-	-	-	-	-
IKIEMMBD_02912	4.16e-122	-	-	-	-	-	-	-	-
IKIEMMBD_02913	2.75e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
IKIEMMBD_02914	2.48e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
IKIEMMBD_02915	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IKIEMMBD_02916	1.7e-90	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IKIEMMBD_02917	5.24e-196	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IKIEMMBD_02918	4.1e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_02919	1.02e-281	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IKIEMMBD_02920	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IKIEMMBD_02921	1.75e-179	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
IKIEMMBD_02922	1.01e-157	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
IKIEMMBD_02923	3.87e-184	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IKIEMMBD_02924	1.6e-294	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IKIEMMBD_02925	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IKIEMMBD_02926	1.3e-198	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IKIEMMBD_02927	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
IKIEMMBD_02928	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKIEMMBD_02929	1.28e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
IKIEMMBD_02930	4.92e-120	yisT	-	-	S	-	-	-	DinB family
IKIEMMBD_02931	6.75e-245	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IKIEMMBD_02932	1.83e-235	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IKIEMMBD_02933	3.88e-205	yisR	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_02934	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
IKIEMMBD_02935	4.6e-191	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
IKIEMMBD_02936	8.83e-114	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
IKIEMMBD_02937	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IKIEMMBD_02938	4.12e-129	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
IKIEMMBD_02939	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IKIEMMBD_02940	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
IKIEMMBD_02941	7.64e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IKIEMMBD_02942	2.29e-223	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IKIEMMBD_02943	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IKIEMMBD_02944	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
IKIEMMBD_02945	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
IKIEMMBD_02946	2.88e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
IKIEMMBD_02947	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
IKIEMMBD_02948	3.35e-87	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
IKIEMMBD_02949	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
IKIEMMBD_02950	6.4e-65	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
IKIEMMBD_02951	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
IKIEMMBD_02952	5.69e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IKIEMMBD_02953	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IKIEMMBD_02954	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
IKIEMMBD_02955	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
IKIEMMBD_02956	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
IKIEMMBD_02957	1.65e-268	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IKIEMMBD_02958	5.88e-258	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
IKIEMMBD_02959	4.36e-239	yhjM	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_02960	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IKIEMMBD_02961	5.31e-205	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
IKIEMMBD_02962	1.33e-255	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IKIEMMBD_02963	7.35e-272	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
IKIEMMBD_02964	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IKIEMMBD_02965	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
IKIEMMBD_02966	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IKIEMMBD_02967	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
IKIEMMBD_02968	4.13e-78	yhjD	-	-	-	-	-	-	-
IKIEMMBD_02969	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IKIEMMBD_02970	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKIEMMBD_02971	1.68e-55	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
IKIEMMBD_02972	8.19e-213	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IKIEMMBD_02973	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
IKIEMMBD_02974	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
IKIEMMBD_02975	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_02976	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IKIEMMBD_02977	5.29e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
IKIEMMBD_02978	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IKIEMMBD_02979	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IKIEMMBD_02980	8.58e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IKIEMMBD_02981	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
IKIEMMBD_02982	1.13e-222	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IKIEMMBD_02983	1.97e-231	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
IKIEMMBD_02984	1.21e-99	-	-	-	K	-	-	-	acetyltransferase
IKIEMMBD_02985	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IKIEMMBD_02986	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
IKIEMMBD_02987	2.78e-85	yhfM	-	-	-	-	-	-	-
IKIEMMBD_02988	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IKIEMMBD_02989	3.02e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
IKIEMMBD_02990	5.54e-243	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IKIEMMBD_02991	3.43e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IKIEMMBD_02992	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKIEMMBD_02993	6.22e-93	-	-	-	S	-	-	-	ASCH
IKIEMMBD_02994	2.68e-253	yhfE	-	-	G	-	-	-	peptidase M42
IKIEMMBD_02995	1.61e-178	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
IKIEMMBD_02996	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IKIEMMBD_02997	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
IKIEMMBD_02998	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_02999	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IKIEMMBD_03000	3.41e-231	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IKIEMMBD_03001	3.17e-260	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IKIEMMBD_03002	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IKIEMMBD_03003	2.18e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IKIEMMBD_03004	1.33e-23	-	-	-	C	-	-	-	Rubrerythrin
IKIEMMBD_03005	8.08e-316	yhfA	-	-	C	-	-	-	membrane
IKIEMMBD_03006	8.91e-291	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IKIEMMBD_03007	1.18e-160	ecsC	-	-	S	-	-	-	EcsC protein family
IKIEMMBD_03008	1.27e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IKIEMMBD_03009	1.1e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
IKIEMMBD_03010	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IKIEMMBD_03011	2.06e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IKIEMMBD_03012	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
IKIEMMBD_03013	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
IKIEMMBD_03014	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
IKIEMMBD_03015	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
IKIEMMBD_03016	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
IKIEMMBD_03017	6.57e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IKIEMMBD_03018	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
IKIEMMBD_03019	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
IKIEMMBD_03020	0.0	yhaN	-	-	L	-	-	-	AAA domain
IKIEMMBD_03021	1.34e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
IKIEMMBD_03022	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
IKIEMMBD_03023	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_03024	1.1e-34	-	-	-	S	-	-	-	YhzD-like protein
IKIEMMBD_03025	1.32e-171	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
IKIEMMBD_03027	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IKIEMMBD_03028	2.63e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
IKIEMMBD_03029	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
IKIEMMBD_03030	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IKIEMMBD_03031	1.58e-262	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IKIEMMBD_03032	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IKIEMMBD_03033	6.89e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
IKIEMMBD_03034	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IKIEMMBD_03035	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IKIEMMBD_03036	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
IKIEMMBD_03037	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IKIEMMBD_03038	7.48e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
IKIEMMBD_03039	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IKIEMMBD_03040	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IKIEMMBD_03041	3.16e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
IKIEMMBD_03042	3.45e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IKIEMMBD_03043	3.16e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IKIEMMBD_03044	4.69e-199	nodB1	-	-	G	-	-	-	deacetylase
IKIEMMBD_03045	1.69e-179	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IKIEMMBD_03046	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
IKIEMMBD_03047	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
IKIEMMBD_03048	3.15e-173	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IKIEMMBD_03049	3.38e-86	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IKIEMMBD_03050	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IKIEMMBD_03051	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IKIEMMBD_03052	5.1e-284	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IKIEMMBD_03053	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
IKIEMMBD_03054	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IKIEMMBD_03055	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IKIEMMBD_03056	9.58e-244	yhdN	-	-	C	-	-	-	Aldo keto reductase
IKIEMMBD_03057	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_03058	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
IKIEMMBD_03059	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
IKIEMMBD_03060	7.13e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKIEMMBD_03061	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKIEMMBD_03062	5e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IKIEMMBD_03063	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
IKIEMMBD_03064	1.92e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_03065	1.06e-260	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IKIEMMBD_03066	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_03067	1.05e-199	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IKIEMMBD_03068	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IKIEMMBD_03069	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
IKIEMMBD_03070	8.32e-304	ygxB	-	-	M	-	-	-	Conserved TM helix
IKIEMMBD_03071	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
IKIEMMBD_03072	1.66e-272	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IKIEMMBD_03073	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IKIEMMBD_03074	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
IKIEMMBD_03075	1.34e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
IKIEMMBD_03076	1.9e-144	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKIEMMBD_03077	1.54e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_03078	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
IKIEMMBD_03079	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IKIEMMBD_03080	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IKIEMMBD_03081	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IKIEMMBD_03082	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IKIEMMBD_03083	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IKIEMMBD_03084	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IKIEMMBD_03085	2.5e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
IKIEMMBD_03086	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IKIEMMBD_03087	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
IKIEMMBD_03088	1.94e-217	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IKIEMMBD_03089	3.07e-135	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IKIEMMBD_03090	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IKIEMMBD_03091	9.74e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
IKIEMMBD_03092	3.96e-227	yhcP	-	-	-	-	-	-	-
IKIEMMBD_03093	6.46e-103	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IKIEMMBD_03094	1.13e-70	yhcM	-	-	-	-	-	-	-
IKIEMMBD_03095	1.76e-299	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKIEMMBD_03096	7.08e-251	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
IKIEMMBD_03097	2.49e-191	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IKIEMMBD_03098	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IKIEMMBD_03099	2.83e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IKIEMMBD_03100	1.46e-209	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_03101	7.64e-155	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_03102	1.95e-78	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_03103	5.86e-69	-	-	-	-	-	-	-	-
IKIEMMBD_03104	3.95e-59	yhcC	-	-	-	-	-	-	-
IKIEMMBD_03105	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
IKIEMMBD_03106	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IKIEMMBD_03107	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
IKIEMMBD_03108	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
IKIEMMBD_03109	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
IKIEMMBD_03110	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
IKIEMMBD_03111	4.08e-110	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IKIEMMBD_03112	2.29e-96	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IKIEMMBD_03113	9.75e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
IKIEMMBD_03114	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IKIEMMBD_03115	4.79e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
IKIEMMBD_03116	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IKIEMMBD_03117	1.11e-146	yhzB	-	-	S	-	-	-	B3/4 domain
IKIEMMBD_03119	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_03120	6.58e-101	ygaO	-	-	-	-	-	-	-
IKIEMMBD_03121	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IKIEMMBD_03124	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
IKIEMMBD_03125	5.86e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IKIEMMBD_03126	6.93e-217	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
IKIEMMBD_03127	1.74e-176	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IKIEMMBD_03128	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IKIEMMBD_03130	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
IKIEMMBD_03131	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IKIEMMBD_03132	2.31e-105	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
IKIEMMBD_03133	1.33e-19	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
IKIEMMBD_03134	1.58e-36	-	-	-	-	-	-	-	-
IKIEMMBD_03135	2.13e-183	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
IKIEMMBD_03152	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IKIEMMBD_03153	2.36e-214	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
IKIEMMBD_03154	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
IKIEMMBD_03155	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IKIEMMBD_03156	1.69e-112	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
IKIEMMBD_03157	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IKIEMMBD_03158	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
IKIEMMBD_03159	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
IKIEMMBD_03160	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IKIEMMBD_03161	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
IKIEMMBD_03162	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
IKIEMMBD_03163	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_03164	1.73e-48	yfhS	-	-	-	-	-	-	-
IKIEMMBD_03165	1.99e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
IKIEMMBD_03166	7.22e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
IKIEMMBD_03167	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IKIEMMBD_03168	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IKIEMMBD_03169	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
IKIEMMBD_03170	1.81e-65	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
IKIEMMBD_03171	3.58e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
IKIEMMBD_03172	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
IKIEMMBD_03173	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
IKIEMMBD_03174	1.41e-267	yfhI	-	-	EGP	-	-	-	-transporter
IKIEMMBD_03176	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
IKIEMMBD_03177	3.25e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IKIEMMBD_03178	1.13e-221	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
IKIEMMBD_03180	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
IKIEMMBD_03181	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
IKIEMMBD_03182	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
IKIEMMBD_03183	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_03184	2.1e-223	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_03185	9.42e-232	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IKIEMMBD_03186	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IKIEMMBD_03187	8.59e-103	yfiV	-	-	K	-	-	-	transcriptional
IKIEMMBD_03188	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
IKIEMMBD_03189	1.1e-125	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
IKIEMMBD_03190	1.33e-252	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IKIEMMBD_03191	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IKIEMMBD_03192	1.89e-128	padR	-	-	K	-	-	-	transcriptional
IKIEMMBD_03193	8.09e-261	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IKIEMMBD_03194	1.78e-265	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IKIEMMBD_03195	3.08e-214	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_03196	1.01e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
IKIEMMBD_03197	1.7e-272	baeS	-	-	T	-	-	-	Histidine kinase
IKIEMMBD_03199	1.72e-207	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IKIEMMBD_03200	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
IKIEMMBD_03201	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IKIEMMBD_03202	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IKIEMMBD_03203	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_03204	8.69e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IKIEMMBD_03205	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IKIEMMBD_03206	1.08e-58	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
IKIEMMBD_03207	5.56e-270	yfjB	-	-	-	-	-	-	-
IKIEMMBD_03208	4.15e-184	yfjC	-	-	-	-	-	-	-
IKIEMMBD_03209	3.52e-130	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
IKIEMMBD_03210	7.42e-75	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
IKIEMMBD_03211	2.87e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
IKIEMMBD_03212	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
IKIEMMBD_03213	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IKIEMMBD_03214	9.43e-262	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKIEMMBD_03215	2.26e-243	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IKIEMMBD_03216	2.75e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IKIEMMBD_03217	9.62e-68	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
IKIEMMBD_03218	1.68e-23	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
IKIEMMBD_03219	4.53e-239	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IKIEMMBD_03220	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKIEMMBD_03221	1.94e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IKIEMMBD_03222	4.51e-236	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
IKIEMMBD_03223	5.62e-193	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IKIEMMBD_03224	7.24e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
IKIEMMBD_03225	3.26e-36	yfjT	-	-	-	-	-	-	-
IKIEMMBD_03226	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
IKIEMMBD_03227	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
IKIEMMBD_03228	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
IKIEMMBD_03229	5.44e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
IKIEMMBD_03230	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_03231	1.6e-182	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IKIEMMBD_03232	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
IKIEMMBD_03233	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IKIEMMBD_03234	7.27e-42	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
IKIEMMBD_03235	2.53e-265	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_03236	7.78e-114	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IKIEMMBD_03237	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IKIEMMBD_03238	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
IKIEMMBD_03239	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
IKIEMMBD_03240	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IKIEMMBD_03241	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_03242	5.09e-33	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IKIEMMBD_03243	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
IKIEMMBD_03244	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
IKIEMMBD_03245	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IKIEMMBD_03246	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IKIEMMBD_03247	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IKIEMMBD_03248	6.04e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IKIEMMBD_03249	6.9e-27	yflI	-	-	-	-	-	-	-
IKIEMMBD_03250	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
IKIEMMBD_03251	5.91e-158	yflK	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_03252	2.54e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IKIEMMBD_03253	1.95e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IKIEMMBD_03254	8.08e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IKIEMMBD_03255	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IKIEMMBD_03256	6.89e-231	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
IKIEMMBD_03257	1.33e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IKIEMMBD_03258	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IKIEMMBD_03259	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IKIEMMBD_03260	2.45e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
IKIEMMBD_03261	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
IKIEMMBD_03262	3.01e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
IKIEMMBD_03263	1.6e-218	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IKIEMMBD_03264	2.73e-219	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_03265	5.76e-221	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_03266	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IKIEMMBD_03267	0.0	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
IKIEMMBD_03268	3.46e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
IKIEMMBD_03269	2.84e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
IKIEMMBD_03270	2.55e-105	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
IKIEMMBD_03271	2.42e-262	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
IKIEMMBD_03272	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IKIEMMBD_03273	2.95e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
IKIEMMBD_03274	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
IKIEMMBD_03275	1.31e-98	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
IKIEMMBD_03276	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IKIEMMBD_03277	1.47e-160	yfmS	-	-	NT	-	-	-	chemotaxis protein
IKIEMMBD_03278	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IKIEMMBD_03279	3.41e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
IKIEMMBD_03280	2.13e-167	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IKIEMMBD_03281	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_03282	2.34e-243	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IKIEMMBD_03283	1.16e-284	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
IKIEMMBD_03284	3.28e-230	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IKIEMMBD_03285	1.2e-237	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
IKIEMMBD_03286	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
IKIEMMBD_03287	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IKIEMMBD_03288	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IKIEMMBD_03289	6.1e-255	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
IKIEMMBD_03290	5.07e-38	yetM	-	-	CH	-	-	-	FAD binding domain
IKIEMMBD_03291	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IKIEMMBD_03292	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
IKIEMMBD_03293	5.77e-182	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IKIEMMBD_03294	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKIEMMBD_03295	1.57e-71	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
IKIEMMBD_03296	3.13e-158	yetF	-	-	S	-	-	-	membrane
IKIEMMBD_03297	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IKIEMMBD_03298	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IKIEMMBD_03299	1.18e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IKIEMMBD_03300	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IKIEMMBD_03301	0.0	yetA	-	-	-	-	-	-	-
IKIEMMBD_03302	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
IKIEMMBD_03303	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IKIEMMBD_03304	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IKIEMMBD_03305	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IKIEMMBD_03306	3.3e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IKIEMMBD_03307	7.52e-165	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
IKIEMMBD_03308	5.67e-168	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IKIEMMBD_03309	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_03310	6.57e-253	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
IKIEMMBD_03311	5.11e-210	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IKIEMMBD_03312	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IKIEMMBD_03313	1.44e-314	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IKIEMMBD_03314	1.62e-256	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
IKIEMMBD_03315	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_03316	1.04e-131	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
IKIEMMBD_03317	1.02e-131	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IKIEMMBD_03318	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
IKIEMMBD_03319	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
IKIEMMBD_03320	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
IKIEMMBD_03321	1.23e-195	yesF	-	-	GM	-	-	-	NAD(P)H-binding
IKIEMMBD_03322	4.95e-107	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
IKIEMMBD_03323	4.21e-131	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_03325	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
IKIEMMBD_03327	8.24e-270	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IKIEMMBD_03328	1.97e-35	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
IKIEMMBD_03329	8.78e-163	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
IKIEMMBD_03331	3.46e-127	-	-	-	L	-	-	-	endonuclease activity
IKIEMMBD_03333	1.02e-228	-	-	-	S	-	-	-	Bacterial EndoU nuclease
IKIEMMBD_03334	9.86e-54	-	-	-	S	-	-	-	Immunity protein 22
IKIEMMBD_03335	0.000169	-	-	-	-	-	-	-	-
IKIEMMBD_03336	2.97e-122	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IKIEMMBD_03338	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKIEMMBD_03339	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IKIEMMBD_03340	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IKIEMMBD_03341	4.21e-190	yerO	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_03342	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IKIEMMBD_03343	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IKIEMMBD_03344	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IKIEMMBD_03345	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKIEMMBD_03346	1.32e-159	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
IKIEMMBD_03347	8.56e-251	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
IKIEMMBD_03348	6.9e-279	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
IKIEMMBD_03349	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IKIEMMBD_03350	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IKIEMMBD_03351	4.48e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IKIEMMBD_03352	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
IKIEMMBD_03353	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_03354	6.47e-242	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
IKIEMMBD_03355	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
IKIEMMBD_03356	1.47e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
IKIEMMBD_03357	2.13e-294	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
IKIEMMBD_03358	2.51e-94	-	-	-	K	-	-	-	helix_turn_helix ASNC type
IKIEMMBD_03359	3.29e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IKIEMMBD_03360	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IKIEMMBD_03361	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IKIEMMBD_03362	1.71e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IKIEMMBD_03363	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IKIEMMBD_03364	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IKIEMMBD_03365	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IKIEMMBD_03366	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IKIEMMBD_03367	2.04e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IKIEMMBD_03368	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IKIEMMBD_03369	2.12e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IKIEMMBD_03370	1.08e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IKIEMMBD_03371	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
IKIEMMBD_03372	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
IKIEMMBD_03374	2.38e-164	yebC	-	-	M	-	-	-	Membrane
IKIEMMBD_03375	1.2e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IKIEMMBD_03376	4.16e-65	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
IKIEMMBD_03377	2.33e-106	-	-	-	-	-	-	-	-
IKIEMMBD_03378	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IKIEMMBD_03379	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
IKIEMMBD_03380	9.17e-285	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IKIEMMBD_03381	2.79e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
IKIEMMBD_03382	1.44e-197	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IKIEMMBD_03383	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IKIEMMBD_03384	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
IKIEMMBD_03385	1.68e-227	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
IKIEMMBD_03386	8.13e-199	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IKIEMMBD_03387	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
IKIEMMBD_03389	7.24e-211	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
IKIEMMBD_03390	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
IKIEMMBD_03391	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
IKIEMMBD_03392	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IKIEMMBD_03393	3.93e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
IKIEMMBD_03394	1.79e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
IKIEMMBD_03395	1.09e-174	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
IKIEMMBD_03396	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IKIEMMBD_03397	8.88e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
IKIEMMBD_03398	7.03e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IKIEMMBD_03399	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
IKIEMMBD_03400	1.69e-255	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IKIEMMBD_03401	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
IKIEMMBD_03402	2.99e-190	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
IKIEMMBD_03403	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IKIEMMBD_03404	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IKIEMMBD_03405	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IKIEMMBD_03406	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
IKIEMMBD_03407	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IKIEMMBD_03408	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IKIEMMBD_03409	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IKIEMMBD_03410	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IKIEMMBD_03411	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IKIEMMBD_03412	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IKIEMMBD_03413	1.71e-109	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IKIEMMBD_03414	1.14e-159	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
IKIEMMBD_03415	3.68e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
IKIEMMBD_03416	1.75e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IKIEMMBD_03419	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IKIEMMBD_03422	4.89e-202	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
IKIEMMBD_03423	4.76e-271	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
IKIEMMBD_03424	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IKIEMMBD_03425	9.97e-214	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
IKIEMMBD_03426	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IKIEMMBD_03427	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IKIEMMBD_03428	2.27e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKIEMMBD_03429	1.44e-68	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_03430	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_03431	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IKIEMMBD_03432	1.4e-128	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
IKIEMMBD_03433	3.52e-227	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IKIEMMBD_03434	1.61e-109	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IKIEMMBD_03436	5.54e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
IKIEMMBD_03437	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IKIEMMBD_03438	4.11e-161	-	-	-	-	-	-	-	-
IKIEMMBD_03439	7.9e-289	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IKIEMMBD_03440	7.33e-309	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
IKIEMMBD_03441	5.24e-158	ydhC	-	-	K	-	-	-	FCD
IKIEMMBD_03442	5.07e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IKIEMMBD_03443	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
IKIEMMBD_03444	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IKIEMMBD_03445	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
IKIEMMBD_03446	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
IKIEMMBD_03447	9.78e-103	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IKIEMMBD_03448	5.94e-118	-	-	-	S	-	-	-	DinB family
IKIEMMBD_03449	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IKIEMMBD_03450	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
IKIEMMBD_03451	4.53e-132	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
IKIEMMBD_03452	6.82e-240	xylT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IKIEMMBD_03453	1.16e-151	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IKIEMMBD_03454	2.55e-168	idhA	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IKIEMMBD_03455	2.79e-40	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
IKIEMMBD_03456	9.78e-112	yycN	-	-	K	-	-	-	Acetyltransferase
IKIEMMBD_03457	4.73e-69	-	-	-	S	-	-	-	DoxX-like family
IKIEMMBD_03458	1.41e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IKIEMMBD_03459	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IKIEMMBD_03460	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IKIEMMBD_03461	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IKIEMMBD_03462	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
IKIEMMBD_03463	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
IKIEMMBD_03465	3.75e-39	-	-	-	-	-	-	-	-
IKIEMMBD_03466	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IKIEMMBD_03467	2.1e-71	ydfQ	-	-	CO	-	-	-	Thioredoxin
IKIEMMBD_03468	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
IKIEMMBD_03469	4.51e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IKIEMMBD_03470	7.8e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
IKIEMMBD_03471	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IKIEMMBD_03472	1.67e-75	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
IKIEMMBD_03476	3.65e-13	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IKIEMMBD_03478	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IKIEMMBD_03479	2.27e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IKIEMMBD_03480	1.09e-222	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IKIEMMBD_03481	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
IKIEMMBD_03482	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKIEMMBD_03483	7.92e-251	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_03485	7.61e-102	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IKIEMMBD_03486	3.03e-158	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IKIEMMBD_03487	1.64e-148	ydfE	-	-	S	-	-	-	Flavin reductase like domain
IKIEMMBD_03488	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKIEMMBD_03489	3.56e-190	-	-	-	EG	-	-	-	EamA-like transporter family
IKIEMMBD_03490	1.1e-188	-	-	-	J	-	-	-	GNAT acetyltransferase
IKIEMMBD_03491	1.06e-295	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IKIEMMBD_03492	2.11e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
IKIEMMBD_03493	1.78e-134	ydeS	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_03494	9.71e-258	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IKIEMMBD_03495	6.98e-142	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
IKIEMMBD_03496	1.19e-89	ydeP	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_03497	1.96e-195	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IKIEMMBD_03498	2.13e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IKIEMMBD_03499	3.37e-135	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
IKIEMMBD_03500	1.06e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
IKIEMMBD_03501	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKIEMMBD_03502	5.21e-194	ydeK	-	-	EG	-	-	-	-transporter
IKIEMMBD_03503	4.22e-111	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IKIEMMBD_03504	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IKIEMMBD_03505	2.4e-41	-	-	-	S	-	-	-	SNARE associated Golgi protein
IKIEMMBD_03506	2.97e-135	-	-	-	-	-	-	-	-
IKIEMMBD_03507	4.53e-132	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
IKIEMMBD_03508	2.64e-69	ydeH	-	-	-	-	-	-	-
IKIEMMBD_03509	2.1e-274	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
IKIEMMBD_03510	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKIEMMBD_03511	7.88e-211	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
IKIEMMBD_03512	7.59e-219	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IKIEMMBD_03513	5.14e-212	-	-	-	K	-	-	-	AraC-like ligand binding domain
IKIEMMBD_03514	2.79e-181	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IKIEMMBD_03515	1.7e-101	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
IKIEMMBD_03516	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
IKIEMMBD_03517	7.88e-244	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
IKIEMMBD_03518	1.21e-52	-	-	-	-	-	-	-	-
IKIEMMBD_03519	1.8e-45	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IKIEMMBD_03520	1.61e-177	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IKIEMMBD_03521	6.9e-13	-	-	-	M	-	-	-	TIGRFAM YD repeat protein
IKIEMMBD_03522	9.42e-57	-	-	-	-	-	-	-	-
IKIEMMBD_03523	3.99e-96	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IKIEMMBD_03531	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IKIEMMBD_03532	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
IKIEMMBD_03533	6.26e-101	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IKIEMMBD_03534	3.78e-106	ydcG	-	-	S	-	-	-	EVE domain
IKIEMMBD_03538	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
IKIEMMBD_03539	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKIEMMBD_03540	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IKIEMMBD_03541	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
IKIEMMBD_03542	1.86e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
IKIEMMBD_03543	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IKIEMMBD_03544	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
IKIEMMBD_03545	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
IKIEMMBD_03546	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IKIEMMBD_03547	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IKIEMMBD_03548	1.19e-280	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IKIEMMBD_03549	1.9e-233	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
IKIEMMBD_03550	1.32e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IKIEMMBD_03551	1.03e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
IKIEMMBD_03552	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
IKIEMMBD_03553	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IKIEMMBD_03554	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IKIEMMBD_03555	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IKIEMMBD_03556	1.03e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IKIEMMBD_03557	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
IKIEMMBD_03558	7.78e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IKIEMMBD_03560	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
IKIEMMBD_03561	1.83e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
IKIEMMBD_03562	9.32e-70	ydbL	-	-	-	-	-	-	-
IKIEMMBD_03563	4.25e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IKIEMMBD_03564	2.28e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_03565	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
IKIEMMBD_03566	8.93e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKIEMMBD_03567	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IKIEMMBD_03568	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IKIEMMBD_03569	1.49e-252	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IKIEMMBD_03570	1.06e-195	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
IKIEMMBD_03571	1.49e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
IKIEMMBD_03572	3.61e-77	ydbB	-	-	G	-	-	-	Cupin domain
IKIEMMBD_03573	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
IKIEMMBD_03574	9.72e-187	ydbA	-	-	P	-	-	-	EcsC protein family
IKIEMMBD_03575	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IKIEMMBD_03576	1.67e-42	ydaS	-	-	S	-	-	-	membrane
IKIEMMBD_03577	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IKIEMMBD_03578	2.14e-53	-	-	-	-	-	-	-	-
IKIEMMBD_03579	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IKIEMMBD_03580	2.28e-86	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IKIEMMBD_03581	0.0	ydaO	-	-	E	-	-	-	amino acid
IKIEMMBD_03582	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
IKIEMMBD_03583	1.12e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IKIEMMBD_03584	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
IKIEMMBD_03585	1.56e-193	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IKIEMMBD_03586	5.97e-265	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IKIEMMBD_03587	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IKIEMMBD_03588	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IKIEMMBD_03589	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
IKIEMMBD_03590	7.59e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IKIEMMBD_03591	1.5e-100	ydaG	-	-	S	-	-	-	general stress protein
IKIEMMBD_03592	1.18e-127	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IKIEMMBD_03593	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
IKIEMMBD_03594	8.81e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_03595	1.53e-122	ydaC	-	-	Q	-	-	-	Methyltransferase domain
IKIEMMBD_03596	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
IKIEMMBD_03597	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
IKIEMMBD_03598	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
IKIEMMBD_03599	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
IKIEMMBD_03600	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
IKIEMMBD_03602	5.94e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
IKIEMMBD_03603	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_03604	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
IKIEMMBD_03605	9.77e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
IKIEMMBD_03606	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
IKIEMMBD_03607	1.32e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
IKIEMMBD_03608	1.1e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
IKIEMMBD_03609	1.1e-176	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IKIEMMBD_03611	2.29e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IKIEMMBD_03612	1.3e-138	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
IKIEMMBD_03613	3.44e-94	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IKIEMMBD_03615	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
IKIEMMBD_03616	5.13e-267	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
IKIEMMBD_03617	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IKIEMMBD_03618	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
IKIEMMBD_03619	9.44e-75	-	-	-	-	-	-	-	-
IKIEMMBD_03620	1.22e-137	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IKIEMMBD_03621	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
IKIEMMBD_03622	3.99e-134	ycnI	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_03623	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKIEMMBD_03624	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
IKIEMMBD_03625	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IKIEMMBD_03626	5.64e-312	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IKIEMMBD_03627	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKIEMMBD_03628	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IKIEMMBD_03629	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
IKIEMMBD_03630	2.48e-173	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IKIEMMBD_03631	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
IKIEMMBD_03632	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
IKIEMMBD_03633	3.3e-212	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
IKIEMMBD_03634	5.63e-176	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_03635	1.29e-208	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_03636	8.97e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_03637	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IKIEMMBD_03639	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IKIEMMBD_03641	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IKIEMMBD_03642	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IKIEMMBD_03643	5.43e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_03644	4.04e-277	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
IKIEMMBD_03645	5.63e-154	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IKIEMMBD_03646	3.33e-247	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
IKIEMMBD_03647	1.62e-294	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
IKIEMMBD_03648	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IKIEMMBD_03650	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
IKIEMMBD_03651	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
IKIEMMBD_03652	5.28e-200	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
IKIEMMBD_03653	6.65e-104	yclD	-	-	-	-	-	-	-
IKIEMMBD_03654	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
IKIEMMBD_03655	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IKIEMMBD_03656	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IKIEMMBD_03657	5.32e-209	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
IKIEMMBD_03658	6.84e-185	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IKIEMMBD_03659	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IKIEMMBD_03660	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IKIEMMBD_03661	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
IKIEMMBD_03662	4.76e-145	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
IKIEMMBD_03663	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
IKIEMMBD_03664	8.03e-206	ycxC	-	-	EG	-	-	-	EamA-like transporter family
IKIEMMBD_03665	7.04e-121	-	-	-	S	-	-	-	YcxB-like protein
IKIEMMBD_03666	6.26e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IKIEMMBD_03667	5.47e-178	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
IKIEMMBD_03668	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
IKIEMMBD_03669	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_03670	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKIEMMBD_03671	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
IKIEMMBD_03672	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
IKIEMMBD_03673	1.32e-125	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
IKIEMMBD_03674	1.24e-266	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IKIEMMBD_03675	3.23e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IKIEMMBD_03676	3.93e-90	nin	-	-	S	-	-	-	Competence protein J (ComJ)
IKIEMMBD_03677	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IKIEMMBD_03678	1.35e-153	-	-	-	S	-	-	-	AAA domain
IKIEMMBD_03679	9e-32	-	-	-	-	-	-	-	-
IKIEMMBD_03680	1.29e-58	-	-	-	K	-	-	-	MarR family
IKIEMMBD_03681	5.86e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
IKIEMMBD_03682	4.14e-62	yckC	-	-	S	-	-	-	membrane
IKIEMMBD_03684	3.76e-187	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IKIEMMBD_03685	4.96e-148	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IKIEMMBD_03686	6.78e-291	yciC	-	-	S	-	-	-	GTPases (G3E family)
IKIEMMBD_03687	2.97e-131	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IKIEMMBD_03688	5.58e-218	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
IKIEMMBD_03689	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IKIEMMBD_03690	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
IKIEMMBD_03691	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IKIEMMBD_03692	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IKIEMMBD_03693	4.9e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
IKIEMMBD_03694	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IKIEMMBD_03695	8.9e-247	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IKIEMMBD_03696	7.86e-208	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
IKIEMMBD_03697	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
IKIEMMBD_03698	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
IKIEMMBD_03699	4.57e-287	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
IKIEMMBD_03700	2.64e-316	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKIEMMBD_03701	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IKIEMMBD_03702	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IKIEMMBD_03703	7.76e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
IKIEMMBD_03704	3.16e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
IKIEMMBD_03705	6.04e-223	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
IKIEMMBD_03706	6.15e-185	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
IKIEMMBD_03707	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IKIEMMBD_03709	1.79e-138	tmrB	-	-	S	-	-	-	AAA domain
IKIEMMBD_03710	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IKIEMMBD_03711	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
IKIEMMBD_03712	1.96e-315	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IKIEMMBD_03713	3.07e-194	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
IKIEMMBD_03714	2.61e-146	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
IKIEMMBD_03715	3.04e-100	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IKIEMMBD_03716	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
IKIEMMBD_03717	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IKIEMMBD_03718	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IKIEMMBD_03719	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
IKIEMMBD_03720	2.72e-105	ycgB	-	-	-	-	-	-	-
IKIEMMBD_03721	0.0	ycgA	-	-	S	-	-	-	Membrane
IKIEMMBD_03722	2.4e-277	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
IKIEMMBD_03723	1.16e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IKIEMMBD_03724	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IKIEMMBD_03725	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
IKIEMMBD_03726	1.97e-60	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IKIEMMBD_03727	7.2e-262	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IKIEMMBD_03728	5.45e-278	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
IKIEMMBD_03729	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
IKIEMMBD_03730	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
IKIEMMBD_03731	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
IKIEMMBD_03732	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IKIEMMBD_03733	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IKIEMMBD_03734	3.75e-141	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
IKIEMMBD_03735	1.91e-234	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKIEMMBD_03736	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IKIEMMBD_03737	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IKIEMMBD_03738	3.93e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IKIEMMBD_03739	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IKIEMMBD_03740	3.96e-179	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
IKIEMMBD_03741	6.72e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
IKIEMMBD_03742	2.65e-123	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IKIEMMBD_03743	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_03744	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_03745	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
IKIEMMBD_03746	7.95e-221	yccK	-	-	C	-	-	-	Aldo keto reductase
IKIEMMBD_03747	3.8e-255	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IKIEMMBD_03748	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IKIEMMBD_03749	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IKIEMMBD_03750	3.2e-215	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IKIEMMBD_03751	1.01e-254	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
IKIEMMBD_03752	1.14e-73	-	-	-	S	-	-	-	RDD family
IKIEMMBD_03753	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IKIEMMBD_03754	2.92e-258	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IKIEMMBD_03755	1.88e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IKIEMMBD_03756	2.51e-302	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IKIEMMBD_03757	1.19e-259	ycbU	-	-	E	-	-	-	Selenocysteine lyase
IKIEMMBD_03758	1.34e-151	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IKIEMMBD_03759	1.26e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IKIEMMBD_03760	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IKIEMMBD_03761	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
IKIEMMBD_03762	2.59e-172	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
IKIEMMBD_03763	5.22e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
IKIEMMBD_03764	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IKIEMMBD_03765	8.21e-148	-	-	-	S	-	-	-	ABC-2 family transporter protein
IKIEMMBD_03766	1.31e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IKIEMMBD_03767	5.56e-217	ycbM	-	-	T	-	-	-	Histidine kinase
IKIEMMBD_03768	5.28e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKIEMMBD_03769	4.05e-215	eamA1	-	-	EG	-	-	-	spore germination
IKIEMMBD_03770	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
IKIEMMBD_03771	4.59e-218	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
IKIEMMBD_03772	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IKIEMMBD_03773	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
IKIEMMBD_03774	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IKIEMMBD_03775	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_03776	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IKIEMMBD_03777	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
IKIEMMBD_03778	9.96e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
IKIEMMBD_03779	9.74e-292	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IKIEMMBD_03780	7.22e-237	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IKIEMMBD_03781	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IKIEMMBD_03782	1.24e-231	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
IKIEMMBD_03783	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IKIEMMBD_03784	3.08e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IKIEMMBD_03786	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IKIEMMBD_03787	7.72e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IKIEMMBD_03788	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_03789	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKIEMMBD_03790	2.35e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
IKIEMMBD_03791	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
IKIEMMBD_03792	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
IKIEMMBD_03793	1.58e-59	ybfN	-	-	-	-	-	-	-
IKIEMMBD_03794	2.06e-188	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IKIEMMBD_03795	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
IKIEMMBD_03796	5.67e-123	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IKIEMMBD_03797	9.22e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IKIEMMBD_03799	3.4e-228	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
IKIEMMBD_03800	1.95e-272	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IKIEMMBD_03801	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
IKIEMMBD_03802	8.37e-205	ybfH	-	-	EG	-	-	-	EamA-like transporter family
IKIEMMBD_03803	7.54e-284	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
IKIEMMBD_03804	1.73e-217	ybfA	-	-	K	-	-	-	FR47-like protein
IKIEMMBD_03805	4.89e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IKIEMMBD_03806	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
IKIEMMBD_03807	2.09e-212	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
IKIEMMBD_03808	0.0	ybeC	-	-	E	-	-	-	amino acid
IKIEMMBD_03809	1.11e-54	ybyB	-	-	-	-	-	-	-
IKIEMMBD_03810	1.09e-313	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
IKIEMMBD_03811	5.27e-193	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
IKIEMMBD_03812	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
IKIEMMBD_03813	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
IKIEMMBD_03814	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IKIEMMBD_03815	1.33e-275	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
IKIEMMBD_03816	1.56e-194	ybdN	-	-	-	-	-	-	-
IKIEMMBD_03817	1.18e-179	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IKIEMMBD_03819	1.61e-218	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
IKIEMMBD_03820	1.39e-157	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
IKIEMMBD_03821	2.31e-232	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IKIEMMBD_03822	7.97e-73	-	-	-	-	-	-	-	-
IKIEMMBD_03823	9.37e-258	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IKIEMMBD_03824	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
IKIEMMBD_03825	2.96e-79	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IKIEMMBD_03826	4.6e-63	-	-	-	-	-	-	-	-
IKIEMMBD_03828	1.4e-120	ybcF	-	-	P	-	-	-	carbonic anhydrase
IKIEMMBD_03829	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
IKIEMMBD_03830	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IKIEMMBD_03831	7.9e-127	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin ABC transporter permease
IKIEMMBD_03832	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IKIEMMBD_03833	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IKIEMMBD_03834	3.41e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_03835	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IKIEMMBD_03836	1.52e-149	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IKIEMMBD_03837	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IKIEMMBD_03843	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
IKIEMMBD_03844	2.58e-113	ybbJ	-	-	J	-	-	-	acetyltransferase
IKIEMMBD_03845	1.58e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IKIEMMBD_03846	5.21e-192	ybbH	-	-	K	-	-	-	transcriptional
IKIEMMBD_03847	2.09e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IKIEMMBD_03848	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
IKIEMMBD_03849	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
IKIEMMBD_03850	1.64e-302	ybbC	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_03851	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
IKIEMMBD_03852	8.12e-213	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
IKIEMMBD_03853	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_03854	3.51e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKIEMMBD_03855	6.65e-183	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
IKIEMMBD_03856	2.34e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
IKIEMMBD_03858	2.61e-316	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IKIEMMBD_03859	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IKIEMMBD_03864	2.4e-76	-	-	-	-	-	-	-	-
IKIEMMBD_03866	5.01e-255	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IKIEMMBD_03867	3.42e-55	-	-	-	-	-	-	-	-
IKIEMMBD_03869	1.86e-23	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IKIEMMBD_03870	1.92e-40	-	-	-	-	-	-	-	-
IKIEMMBD_03872	1.88e-21	-	-	-	-	-	-	-	-
IKIEMMBD_03873	2.22e-155	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
IKIEMMBD_03874	1.6e-71	-	-	-	K	-	-	-	DNA binding
IKIEMMBD_03878	1.56e-45	-	-	-	-	-	-	-	-
IKIEMMBD_03881	3.29e-41	-	-	-	-	-	-	-	-
IKIEMMBD_03882	7.52e-17	bet	-	-	L	-	-	-	RecT family
IKIEMMBD_03883	4.38e-23	-	-	-	-	-	-	-	-
IKIEMMBD_03884	1.62e-15	-	-	-	-	-	-	-	-
IKIEMMBD_03886	9.75e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IKIEMMBD_03887	2.82e-65	bldD	-	-	K	ko:K07110,ko:K21572	-	ko00000,ko02000,ko03000	domain, Protein
IKIEMMBD_03888	2.21e-28	-	-	-	-	-	-	-	-
IKIEMMBD_03890	2.75e-35	-	-	-	L	-	-	-	Phage integrase family
IKIEMMBD_03891	3.34e-39	-	-	-	L	-	-	-	Phage integrase family
IKIEMMBD_03894	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IKIEMMBD_03895	1.23e-180	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
IKIEMMBD_03896	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
IKIEMMBD_03897	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
IKIEMMBD_03898	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IKIEMMBD_03899	9.05e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IKIEMMBD_03900	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
IKIEMMBD_03901	2.14e-186	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
IKIEMMBD_03902	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IKIEMMBD_03903	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IKIEMMBD_03904	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IKIEMMBD_03905	3.23e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKIEMMBD_03906	1.83e-193	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKIEMMBD_03907	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKIEMMBD_03908	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IKIEMMBD_03909	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKIEMMBD_03910	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IKIEMMBD_03911	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IKIEMMBD_03912	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IKIEMMBD_03913	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IKIEMMBD_03914	4.68e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IKIEMMBD_03915	6.17e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IKIEMMBD_03916	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IKIEMMBD_03917	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IKIEMMBD_03918	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IKIEMMBD_03919	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IKIEMMBD_03920	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IKIEMMBD_03921	2.58e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IKIEMMBD_03922	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IKIEMMBD_03923	1.67e-38	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IKIEMMBD_03924	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IKIEMMBD_03925	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IKIEMMBD_03926	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IKIEMMBD_03927	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IKIEMMBD_03928	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IKIEMMBD_03929	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IKIEMMBD_03930	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IKIEMMBD_03931	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IKIEMMBD_03932	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IKIEMMBD_03933	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IKIEMMBD_03934	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IKIEMMBD_03935	7.98e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IKIEMMBD_03936	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IKIEMMBD_03937	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IKIEMMBD_03938	8.78e-238	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
IKIEMMBD_03939	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IKIEMMBD_03940	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IKIEMMBD_03941	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IKIEMMBD_03942	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IKIEMMBD_03943	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
IKIEMMBD_03944	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKIEMMBD_03945	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKIEMMBD_03946	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IKIEMMBD_03947	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IKIEMMBD_03948	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IKIEMMBD_03949	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IKIEMMBD_03950	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IKIEMMBD_03951	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IKIEMMBD_03952	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IKIEMMBD_03953	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IKIEMMBD_03954	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
IKIEMMBD_03955	2.04e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IKIEMMBD_03956	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IKIEMMBD_03957	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IKIEMMBD_03958	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
IKIEMMBD_03959	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IKIEMMBD_03960	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IKIEMMBD_03961	1.05e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IKIEMMBD_03962	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
IKIEMMBD_03963	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IKIEMMBD_03964	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IKIEMMBD_03965	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
IKIEMMBD_03966	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IKIEMMBD_03967	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
IKIEMMBD_03968	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IKIEMMBD_03969	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IKIEMMBD_03979	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IKIEMMBD_03980	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IKIEMMBD_03981	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IKIEMMBD_03982	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
IKIEMMBD_03983	2.64e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IKIEMMBD_03984	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IKIEMMBD_03985	1.11e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IKIEMMBD_03986	1.54e-214	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
IKIEMMBD_03987	1.72e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
IKIEMMBD_03988	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IKIEMMBD_03989	4.4e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IKIEMMBD_03990	2.23e-194	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
IKIEMMBD_03991	7.84e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IKIEMMBD_03992	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IKIEMMBD_03993	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IKIEMMBD_03994	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
IKIEMMBD_03995	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IKIEMMBD_03996	4e-235	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IKIEMMBD_03997	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IKIEMMBD_03998	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
IKIEMMBD_04001	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IKIEMMBD_04002	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IKIEMMBD_04003	2.48e-136	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
IKIEMMBD_04004	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
IKIEMMBD_04005	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IKIEMMBD_04006	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IKIEMMBD_04007	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKIEMMBD_04008	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
IKIEMMBD_04009	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IKIEMMBD_04010	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
IKIEMMBD_04011	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IKIEMMBD_04012	4.79e-126	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IKIEMMBD_04013	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IKIEMMBD_04014	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IKIEMMBD_04015	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IKIEMMBD_04016	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
IKIEMMBD_04017	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IKIEMMBD_04018	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IKIEMMBD_04019	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
IKIEMMBD_04020	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_04021	1.84e-197	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
IKIEMMBD_04022	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IKIEMMBD_04023	1.66e-124	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IKIEMMBD_04024	4.1e-278	yabE	-	-	T	-	-	-	protein conserved in bacteria
IKIEMMBD_04025	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
IKIEMMBD_04026	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IKIEMMBD_04027	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
IKIEMMBD_04028	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IKIEMMBD_04029	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
IKIEMMBD_04030	2.7e-176	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
IKIEMMBD_04031	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IKIEMMBD_04032	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
IKIEMMBD_04033	2.42e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IKIEMMBD_04034	7.32e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
IKIEMMBD_04035	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
IKIEMMBD_04036	6.64e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IKIEMMBD_04037	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
IKIEMMBD_04038	1.02e-259	yaaN	-	-	P	-	-	-	Belongs to the TelA family
IKIEMMBD_04039	7.73e-132	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IKIEMMBD_04040	1.82e-41	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
IKIEMMBD_04041	2.16e-48	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
IKIEMMBD_04042	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IKIEMMBD_04043	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IKIEMMBD_04044	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IKIEMMBD_04045	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IKIEMMBD_04046	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IKIEMMBD_04047	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
IKIEMMBD_04048	2.11e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
IKIEMMBD_04049	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
IKIEMMBD_04050	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
IKIEMMBD_04052	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IKIEMMBD_04053	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IKIEMMBD_04054	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IKIEMMBD_04055	3.56e-314	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IKIEMMBD_04056	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IKIEMMBD_04057	2.14e-232	yaaC	-	-	S	-	-	-	YaaC-like Protein
IKIEMMBD_04058	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group