ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NPDJDOHC_00001 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00002 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00003 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00004 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NPDJDOHC_00005 5.93e-283 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NPDJDOHC_00006 1.17e-307 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NPDJDOHC_00007 2.05e-176 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NPDJDOHC_00008 2.88e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPDJDOHC_00009 6.11e-229 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NPDJDOHC_00010 1.29e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_00011 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NPDJDOHC_00012 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NPDJDOHC_00013 2.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPDJDOHC_00015 1.11e-243 yueF - - S - - - transporter activity
NPDJDOHC_00017 3.89e-77 - - - S - - - YolD-like protein
NPDJDOHC_00018 1.7e-301 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPDJDOHC_00019 2.81e-115 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NPDJDOHC_00020 5.96e-81 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NPDJDOHC_00021 5.45e-231 yqkA - - K - - - GrpB protein
NPDJDOHC_00022 9.32e-81 yqkB - - S - - - Belongs to the HesB IscA family
NPDJDOHC_00023 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
NPDJDOHC_00024 1.05e-228 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NPDJDOHC_00025 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
NPDJDOHC_00026 2.27e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NPDJDOHC_00027 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
NPDJDOHC_00028 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NPDJDOHC_00029 6.7e-286 yqxK - - L - - - DNA helicase
NPDJDOHC_00030 8.39e-78 ansR - - K - - - Transcriptional regulator
NPDJDOHC_00031 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NPDJDOHC_00032 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NPDJDOHC_00033 3.55e-316 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NPDJDOHC_00034 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NPDJDOHC_00035 1.96e-30 - - - - - - - -
NPDJDOHC_00036 4.38e-47 yqkK - - - - - - -
NPDJDOHC_00038 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NPDJDOHC_00039 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NPDJDOHC_00040 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
NPDJDOHC_00041 7.9e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NPDJDOHC_00042 4.26e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NPDJDOHC_00043 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NPDJDOHC_00044 6.08e-274 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NPDJDOHC_00045 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NPDJDOHC_00046 2.36e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NPDJDOHC_00047 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPDJDOHC_00048 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NPDJDOHC_00049 1.01e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
NPDJDOHC_00050 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NPDJDOHC_00051 5.77e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NPDJDOHC_00052 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NPDJDOHC_00053 1.31e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
NPDJDOHC_00054 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NPDJDOHC_00055 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPDJDOHC_00056 5.04e-203 ypuA - - S - - - Secreted protein
NPDJDOHC_00057 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPDJDOHC_00058 1.42e-107 ccdC1 - - O - - - Protein of unknown function (DUF1453)
NPDJDOHC_00059 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NPDJDOHC_00060 4.92e-71 ypuD - - - - - - -
NPDJDOHC_00061 2.76e-270 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NPDJDOHC_00062 9.75e-145 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NPDJDOHC_00063 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NPDJDOHC_00064 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NPDJDOHC_00065 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPDJDOHC_00066 1.99e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NPDJDOHC_00068 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPDJDOHC_00069 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPDJDOHC_00070 1.51e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
NPDJDOHC_00071 1.14e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NPDJDOHC_00072 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NPDJDOHC_00073 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NPDJDOHC_00074 7.38e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NPDJDOHC_00075 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NPDJDOHC_00076 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NPDJDOHC_00077 6.24e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NPDJDOHC_00078 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_00079 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_00080 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NPDJDOHC_00081 1.02e-256 rsiX - - - - - - -
NPDJDOHC_00082 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPDJDOHC_00083 1.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPDJDOHC_00084 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NPDJDOHC_00085 1.14e-257 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NPDJDOHC_00086 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NPDJDOHC_00087 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NPDJDOHC_00088 2.1e-139 ypbE - - M - - - Lysin motif
NPDJDOHC_00089 6.69e-112 ypbF - - S - - - Protein of unknown function (DUF2663)
NPDJDOHC_00090 1.4e-190 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NPDJDOHC_00091 4.07e-138 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NPDJDOHC_00092 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NPDJDOHC_00093 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NPDJDOHC_00094 1.11e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NPDJDOHC_00095 4.58e-214 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NPDJDOHC_00096 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
NPDJDOHC_00097 8.8e-33 ypfA - - M - - - Flagellar protein YcgR
NPDJDOHC_00098 6.52e-05 ypfA - - M - - - type IV pilus assembly PilZ
NPDJDOHC_00099 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
NPDJDOHC_00100 4.97e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NPDJDOHC_00101 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NPDJDOHC_00102 6.18e-240 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPDJDOHC_00103 1.87e-12 - - - S - - - YpzI-like protein
NPDJDOHC_00104 6.19e-136 yphA - - - - - - -
NPDJDOHC_00105 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NPDJDOHC_00106 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NPDJDOHC_00107 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
NPDJDOHC_00108 5.88e-174 yphF - - - - - - -
NPDJDOHC_00109 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NPDJDOHC_00110 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPDJDOHC_00111 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NPDJDOHC_00112 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NPDJDOHC_00113 9.74e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NPDJDOHC_00114 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPDJDOHC_00115 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NPDJDOHC_00116 1.47e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NPDJDOHC_00117 3.47e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NPDJDOHC_00118 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NPDJDOHC_00119 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NPDJDOHC_00120 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NPDJDOHC_00121 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPDJDOHC_00122 6.09e-214 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NPDJDOHC_00123 2.11e-170 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NPDJDOHC_00124 3.43e-155 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NPDJDOHC_00125 3.12e-293 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NPDJDOHC_00126 1.97e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NPDJDOHC_00127 9.08e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NPDJDOHC_00128 5.29e-262 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NPDJDOHC_00129 7.29e-304 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPDJDOHC_00130 6.42e-300 ypiA - - S - - - COG0457 FOG TPR repeat
NPDJDOHC_00131 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
NPDJDOHC_00132 9.97e-103 ypiF - - S - - - Protein of unknown function (DUF2487)
NPDJDOHC_00133 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NPDJDOHC_00134 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NPDJDOHC_00135 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NPDJDOHC_00136 9.19e-137 ypjA - - S - - - membrane
NPDJDOHC_00137 2.05e-182 ypjB - - S - - - sporulation protein
NPDJDOHC_00138 3.63e-292 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NPDJDOHC_00139 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NPDJDOHC_00140 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NPDJDOHC_00141 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPDJDOHC_00142 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NPDJDOHC_00143 1.56e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NPDJDOHC_00144 1.87e-271 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NPDJDOHC_00145 2.16e-282 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPDJDOHC_00146 9.42e-232 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPDJDOHC_00147 3.42e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NPDJDOHC_00148 3.44e-203 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NPDJDOHC_00149 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NPDJDOHC_00150 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NPDJDOHC_00151 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NPDJDOHC_00152 2.03e-106 ypmB - - S - - - protein conserved in bacteria
NPDJDOHC_00153 1.78e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NPDJDOHC_00154 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NPDJDOHC_00155 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NPDJDOHC_00156 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPDJDOHC_00157 4.43e-120 ypoC - - - - - - -
NPDJDOHC_00158 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NPDJDOHC_00159 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPDJDOHC_00160 2e-239 yppC - - S - - - Protein of unknown function (DUF2515)
NPDJDOHC_00161 0.000542 - - - - ko:K06430 - ko00000 -
NPDJDOHC_00165 3.1e-86 yppG - - S - - - YppG-like protein
NPDJDOHC_00166 9.14e-96 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NPDJDOHC_00167 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NPDJDOHC_00168 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NPDJDOHC_00169 1.99e-302 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NPDJDOHC_00171 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
NPDJDOHC_00172 3.27e-129 ypsA - - S - - - Belongs to the UPF0398 family
NPDJDOHC_00173 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPDJDOHC_00174 4.86e-281 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NPDJDOHC_00175 7.1e-102 yqgA - - - - - - -
NPDJDOHC_00176 6.91e-31 - - - S - - - YpzG-like protein
NPDJDOHC_00178 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NPDJDOHC_00179 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NPDJDOHC_00180 2e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPDJDOHC_00181 1.77e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
NPDJDOHC_00182 1.78e-06 - - - S - - - Bacillus cereus group antimicrobial protein
NPDJDOHC_00183 1.32e-131 yrdC - - Q - - - Isochorismatase family
NPDJDOHC_00184 2.34e-128 ydfR - - S - - - Protein of unknown function (DUF421)
NPDJDOHC_00185 2.17e-12 - - - S - - - Bacillus cereus group antimicrobial protein
NPDJDOHC_00186 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
NPDJDOHC_00187 3.46e-143 - - - J - - - Acetyltransferase (GNAT) domain
NPDJDOHC_00188 6.51e-271 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NPDJDOHC_00189 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NPDJDOHC_00190 0.0 ypbR - - S - - - Dynamin family
NPDJDOHC_00191 7.03e-53 ypbS - - S - - - Protein of unknown function (DUF2533)
NPDJDOHC_00192 2.44e-10 - - - - - - - -
NPDJDOHC_00193 8.18e-211 ypcP - - L - - - 5'3' exonuclease
NPDJDOHC_00195 7.37e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NPDJDOHC_00196 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NPDJDOHC_00197 3.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NPDJDOHC_00198 6.59e-40 ypeQ - - S - - - Zinc-finger
NPDJDOHC_00199 7.93e-50 - - - S - - - Protein of unknown function (DUF2564)
NPDJDOHC_00200 1.27e-17 degR - - - - - - -
NPDJDOHC_00201 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NPDJDOHC_00202 1.56e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NPDJDOHC_00203 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NPDJDOHC_00204 2.67e-116 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NPDJDOHC_00205 5.04e-132 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NPDJDOHC_00206 2.1e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NPDJDOHC_00207 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NPDJDOHC_00208 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
NPDJDOHC_00209 3.12e-175 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NPDJDOHC_00210 6.48e-148 ypjP - - S - - - YpjP-like protein
NPDJDOHC_00211 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPDJDOHC_00212 5.2e-118 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPDJDOHC_00213 1.71e-150 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NPDJDOHC_00214 3.69e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NPDJDOHC_00215 1.97e-231 yplP - - K - - - Transcriptional regulator
NPDJDOHC_00216 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NPDJDOHC_00217 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
NPDJDOHC_00218 4.04e-149 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NPDJDOHC_00219 2.58e-176 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NPDJDOHC_00220 4.79e-127 ypmS - - S - - - protein conserved in bacteria
NPDJDOHC_00221 8.22e-90 ypoP - - K - - - transcriptional
NPDJDOHC_00222 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPDJDOHC_00223 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NPDJDOHC_00224 1.02e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NPDJDOHC_00225 0.0 yokA - - L - - - Recombinase
NPDJDOHC_00226 1.34e-167 - - - S - - - A nuclease of the HNH/ENDO VII superfamily with conserved WHH
NPDJDOHC_00227 9.7e-133 yokK - - S - - - SMI1 / KNR4 family
NPDJDOHC_00229 3.39e-110 - - - S ko:K07090 - ko00000 response to heat
NPDJDOHC_00230 2.69e-254 - 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_00231 2.85e-128 - - - T - - - helix_turn_helix, Lux Regulon
NPDJDOHC_00232 8.27e-293 - 1.8.5.4 - S ko:K17218 ko00920,map00920 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
NPDJDOHC_00233 0.0 baeB 3.1.2.6 - P ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Rhodanese Homology Domain
NPDJDOHC_00234 1.2e-115 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPDJDOHC_00235 1.49e-273 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NPDJDOHC_00239 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NPDJDOHC_00240 2e-285 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NPDJDOHC_00241 5.69e-234 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NPDJDOHC_00242 9.32e-92 cgeA - - - ko:K06319 - ko00000 -
NPDJDOHC_00243 6.96e-64 cgeC - - - ko:K06321 - ko00000 -
NPDJDOHC_00244 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NPDJDOHC_00245 7.24e-188 yiiD - - K ko:K06323 - ko00000 acetyltransferase
NPDJDOHC_00247 1.76e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPDJDOHC_00248 1.19e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NPDJDOHC_00249 2.3e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NPDJDOHC_00250 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NPDJDOHC_00251 1.31e-208 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NPDJDOHC_00252 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NPDJDOHC_00253 8.43e-64 yokU - - S - - - YokU-like protein, putative antitoxin
NPDJDOHC_00254 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
NPDJDOHC_00255 1.9e-161 yodN - - - - - - -
NPDJDOHC_00257 9.77e-34 yozD - - S - - - YozD-like protein
NPDJDOHC_00258 3.86e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NPDJDOHC_00259 4.03e-73 yodL - - S - - - YodL-like
NPDJDOHC_00261 1.82e-162 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NPDJDOHC_00262 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NPDJDOHC_00263 1.68e-50 yodI - - - - - - -
NPDJDOHC_00264 3.16e-168 yodH - - Q - - - Methyltransferase
NPDJDOHC_00265 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NPDJDOHC_00266 8.67e-170 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_00267 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NPDJDOHC_00268 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
NPDJDOHC_00269 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPDJDOHC_00270 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
NPDJDOHC_00271 2.39e-225 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NPDJDOHC_00272 4.37e-143 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NPDJDOHC_00273 3.3e-139 yodC - - C - - - nitroreductase
NPDJDOHC_00274 1.2e-74 yodB - - K - - - transcriptional
NPDJDOHC_00275 2.74e-92 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
NPDJDOHC_00276 2.59e-89 iolK - - S - - - tautomerase
NPDJDOHC_00278 4.87e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NPDJDOHC_00279 1.03e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NPDJDOHC_00280 1.05e-30 - - - - - - - -
NPDJDOHC_00281 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
NPDJDOHC_00282 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NPDJDOHC_00283 8.69e-195 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPDJDOHC_00284 2.76e-316 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NPDJDOHC_00286 1.64e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPDJDOHC_00287 4.23e-288 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NPDJDOHC_00288 1.34e-296 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NPDJDOHC_00289 9.26e-145 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NPDJDOHC_00290 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NPDJDOHC_00291 0.0 yojO - - P - - - Von Willebrand factor
NPDJDOHC_00292 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NPDJDOHC_00293 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NPDJDOHC_00294 1.99e-183 - - - S - - - Metallo-beta-lactamase superfamily
NPDJDOHC_00295 2.26e-218 yocS - - S ko:K03453 - ko00000 -transporter
NPDJDOHC_00296 5.08e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NPDJDOHC_00297 3.49e-214 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NPDJDOHC_00298 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NPDJDOHC_00299 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NPDJDOHC_00300 4.69e-43 yozC - - - - - - -
NPDJDOHC_00302 5.32e-75 yozO - - S - - - Bacterial PH domain
NPDJDOHC_00303 6.36e-50 yocN - - - - - - -
NPDJDOHC_00304 9.63e-60 yozN - - - - - - -
NPDJDOHC_00305 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NPDJDOHC_00306 3.51e-13 yocN - - - - - - -
NPDJDOHC_00307 2.71e-13 yocL - - - - - - -
NPDJDOHC_00308 5.24e-78 yocK - - T - - - general stress protein
NPDJDOHC_00310 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPDJDOHC_00311 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NPDJDOHC_00312 5.08e-170 yocH - - M - - - COG1388 FOG LysM repeat
NPDJDOHC_00314 3.47e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NPDJDOHC_00315 1.6e-123 yocC - - - - - - -
NPDJDOHC_00316 6.89e-186 - - - J - - - Protein required for attachment to host cells
NPDJDOHC_00317 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
NPDJDOHC_00318 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPDJDOHC_00319 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NPDJDOHC_00320 3.86e-119 yobW - - - - - - -
NPDJDOHC_00321 2.41e-175 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NPDJDOHC_00322 4.57e-123 yobS - - K - - - Transcriptional regulator
NPDJDOHC_00323 3.17e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NPDJDOHC_00324 3.67e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NPDJDOHC_00325 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NPDJDOHC_00326 1.7e-115 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NPDJDOHC_00327 1.45e-60 - - - - - - - -
NPDJDOHC_00328 2.41e-130 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NPDJDOHC_00330 8.57e-22 yoaF - - - - - - -
NPDJDOHC_00331 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPDJDOHC_00332 3.78e-249 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPDJDOHC_00333 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NPDJDOHC_00334 1.81e-260 yoaB - - EGP - - - the major facilitator superfamily
NPDJDOHC_00335 2.4e-182 yoxB - - - - - - -
NPDJDOHC_00336 1.45e-57 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPDJDOHC_00337 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_00338 6.26e-289 - - - K - - - helix_turn_helix, arabinose operon control protein
NPDJDOHC_00339 4.49e-184 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NPDJDOHC_00340 1.66e-61 - - - L - - - Transposase
NPDJDOHC_00341 1.5e-101 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NPDJDOHC_00342 3.37e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NPDJDOHC_00343 7.2e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPDJDOHC_00344 3.58e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPDJDOHC_00345 7.8e-207 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_00346 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NPDJDOHC_00347 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NPDJDOHC_00348 5.3e-241 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NPDJDOHC_00349 2.42e-204 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_00350 1.36e-07 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPDJDOHC_00351 3.29e-67 - - - K - - - Helix-turn-helix domain
NPDJDOHC_00352 5.85e-257 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
NPDJDOHC_00353 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NPDJDOHC_00354 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
NPDJDOHC_00355 3.97e-125 - - - L - - - Integrase
NPDJDOHC_00357 4.66e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NPDJDOHC_00358 3.69e-312 yoeA - - V - - - MATE efflux family protein
NPDJDOHC_00359 2.44e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NPDJDOHC_00360 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NPDJDOHC_00361 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_00362 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
NPDJDOHC_00363 1.67e-85 yngL - - S - - - Protein of unknown function (DUF1360)
NPDJDOHC_00364 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NPDJDOHC_00365 6.51e-269 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NPDJDOHC_00366 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPDJDOHC_00367 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NPDJDOHC_00368 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NPDJDOHC_00369 8.91e-217 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NPDJDOHC_00370 7.4e-180 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NPDJDOHC_00371 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPDJDOHC_00372 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
NPDJDOHC_00373 1.93e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NPDJDOHC_00374 5.53e-96 yngA - - S - - - membrane
NPDJDOHC_00375 6.17e-191 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NPDJDOHC_00376 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NPDJDOHC_00377 1.44e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPDJDOHC_00378 7.76e-169 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NPDJDOHC_00379 1.94e-247 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NPDJDOHC_00380 3.48e-289 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NPDJDOHC_00381 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
NPDJDOHC_00382 8.91e-162 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NPDJDOHC_00383 2.23e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NPDJDOHC_00384 8.63e-180 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NPDJDOHC_00385 4.25e-291 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NPDJDOHC_00386 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_00387 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_00388 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_00389 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NPDJDOHC_00390 0.0 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
NPDJDOHC_00391 1.61e-165 - - - T - - - Transcriptional regulatory protein, C terminal
NPDJDOHC_00392 8.94e-317 - - - T - - - Histidine kinase
NPDJDOHC_00393 1.8e-70 yvlA - - S - - - Domain of unknown function (DUF4870)
NPDJDOHC_00394 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
NPDJDOHC_00395 3.74e-282 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
NPDJDOHC_00397 0.0 yndJ - - S - - - YndJ-like protein
NPDJDOHC_00398 2.4e-52 - - - S - - - Domain of unknown function (DUF4166)
NPDJDOHC_00399 1.59e-205 yndG - - S - - - DoxX-like family
NPDJDOHC_00400 2.27e-288 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
NPDJDOHC_00401 1.57e-234 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
NPDJDOHC_00402 2.71e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_00403 1.23e-274 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
NPDJDOHC_00404 1.84e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
NPDJDOHC_00405 2.88e-249 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NPDJDOHC_00406 2.82e-234 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
NPDJDOHC_00407 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NPDJDOHC_00408 1.82e-63 ynfC - - - - - - -
NPDJDOHC_00409 3.81e-20 - - - - - - - -
NPDJDOHC_00410 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPDJDOHC_00411 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPDJDOHC_00412 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NPDJDOHC_00413 9.09e-121 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPDJDOHC_00414 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
NPDJDOHC_00415 4.68e-71 yneQ - - - - - - -
NPDJDOHC_00416 1.24e-98 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NPDJDOHC_00417 1.48e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NPDJDOHC_00419 3.46e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NPDJDOHC_00420 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NPDJDOHC_00421 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NPDJDOHC_00422 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NPDJDOHC_00423 1.04e-83 cotM - - O ko:K06335 - ko00000 Spore coat protein
NPDJDOHC_00424 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
NPDJDOHC_00425 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NPDJDOHC_00426 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NPDJDOHC_00427 3.14e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NPDJDOHC_00428 1.28e-32 ynzD - - S - - - Spo0E like sporulation regulatory protein
NPDJDOHC_00429 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NPDJDOHC_00430 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NPDJDOHC_00431 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NPDJDOHC_00432 2.33e-43 ynzC - - S - - - UPF0291 protein
NPDJDOHC_00433 5.22e-145 yneB - - L - - - resolvase
NPDJDOHC_00434 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NPDJDOHC_00435 1.35e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPDJDOHC_00437 2.25e-95 yndM - - S - - - Protein of unknown function (DUF2512)
NPDJDOHC_00438 6.29e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
NPDJDOHC_00439 1.74e-11 - - - - - - - -
NPDJDOHC_00440 9.79e-192 yndL - - S - - - Replication protein
NPDJDOHC_00441 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NPDJDOHC_00442 0.0 yobO - - M - - - Pectate lyase superfamily protein
NPDJDOHC_00444 7.75e-126 yvgO - - - - - - -
NPDJDOHC_00445 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NPDJDOHC_00446 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
NPDJDOHC_00447 4.15e-258 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDJDOHC_00448 3.75e-158 - - - S - - - Domain of unknown function (DUF3885)
NPDJDOHC_00450 1.25e-97 - - - - - - - -
NPDJDOHC_00451 7.16e-132 - - - J - - - Acetyltransferase (GNAT) domain
NPDJDOHC_00452 5.71e-190 yoaP - - K - - - YoaP-like
NPDJDOHC_00453 2.36e-06 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NPDJDOHC_00454 1.07e-239 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NPDJDOHC_00455 3.03e-74 dinB - - S - - - DinB family
NPDJDOHC_00456 2.21e-27 - - - - - - - -
NPDJDOHC_00461 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NPDJDOHC_00462 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NPDJDOHC_00463 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NPDJDOHC_00464 3.29e-280 xylR - - GK - - - ROK family
NPDJDOHC_00465 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NPDJDOHC_00466 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
NPDJDOHC_00467 2.11e-275 mrjp - - G - - - Major royal jelly protein
NPDJDOHC_00469 2.12e-123 - - - - - - - -
NPDJDOHC_00470 4.59e-21 - - - - - - - -
NPDJDOHC_00471 1.27e-10 - - - L - - - Arm DNA-binding domain
NPDJDOHC_00472 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NPDJDOHC_00473 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NPDJDOHC_00474 1.01e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NPDJDOHC_00475 1.15e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPDJDOHC_00476 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NPDJDOHC_00477 3.22e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NPDJDOHC_00478 2.72e-142 ymaB - - S - - - MutT family
NPDJDOHC_00479 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPDJDOHC_00480 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPDJDOHC_00481 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NPDJDOHC_00482 9.42e-29 ymzA - - - - - - -
NPDJDOHC_00483 1.47e-59 - - - - - - - -
NPDJDOHC_00484 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NPDJDOHC_00485 7.63e-221 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPDJDOHC_00486 2.08e-77 ymaF - - S - - - YmaF family
NPDJDOHC_00488 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NPDJDOHC_00489 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NPDJDOHC_00490 7.27e-106 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NPDJDOHC_00491 1.18e-164 ymaC - - S - - - Replication protein
NPDJDOHC_00492 3.03e-06 - - - - - - - -
NPDJDOHC_00493 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NPDJDOHC_00494 2.78e-82 ymzB - - - - - - -
NPDJDOHC_00495 2.21e-153 yoaK - - S - - - Membrane
NPDJDOHC_00496 1.81e-103 nucB - - M - - - Deoxyribonuclease NucA/NucB
NPDJDOHC_00497 4.12e-295 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NPDJDOHC_00498 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
NPDJDOHC_00499 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NPDJDOHC_00500 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00501 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00502 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NPDJDOHC_00503 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NPDJDOHC_00504 4.51e-189 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
NPDJDOHC_00505 6.55e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NPDJDOHC_00506 5.27e-49 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
NPDJDOHC_00507 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NPDJDOHC_00508 4.5e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
NPDJDOHC_00509 1.21e-209 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NPDJDOHC_00510 1.72e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
NPDJDOHC_00512 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPDJDOHC_00513 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPDJDOHC_00514 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
NPDJDOHC_00515 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NPDJDOHC_00516 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NPDJDOHC_00517 7.42e-276 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPDJDOHC_00518 7.41e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NPDJDOHC_00519 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NPDJDOHC_00520 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NPDJDOHC_00521 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NPDJDOHC_00522 1.34e-279 pbpX - - V - - - Beta-lactamase
NPDJDOHC_00523 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPDJDOHC_00524 8.03e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NPDJDOHC_00525 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPDJDOHC_00526 2.46e-180 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NPDJDOHC_00527 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
NPDJDOHC_00528 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
NPDJDOHC_00529 2.12e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NPDJDOHC_00530 4.28e-312 ymfH - - S - - - zinc protease
NPDJDOHC_00531 1.12e-306 albE - - S - - - Peptidase M16
NPDJDOHC_00532 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NPDJDOHC_00533 1.2e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NPDJDOHC_00534 2.71e-297 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_00535 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_00536 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NPDJDOHC_00537 6.32e-42 - - - S - - - YlzJ-like protein
NPDJDOHC_00538 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NPDJDOHC_00539 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPDJDOHC_00540 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPDJDOHC_00541 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NPDJDOHC_00542 1.22e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPDJDOHC_00543 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NPDJDOHC_00544 9.9e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NPDJDOHC_00545 2.17e-56 ymxH - - S - - - YlmC YmxH family
NPDJDOHC_00546 2.51e-300 mlpA - - S - - - Belongs to the peptidase M16 family
NPDJDOHC_00547 3.56e-233 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NPDJDOHC_00548 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NPDJDOHC_00549 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPDJDOHC_00550 4.5e-233 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NPDJDOHC_00551 8.95e-222 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPDJDOHC_00552 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPDJDOHC_00553 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NPDJDOHC_00554 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPDJDOHC_00555 6.16e-63 ylxQ - - J - - - ribosomal protein
NPDJDOHC_00556 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NPDJDOHC_00557 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NPDJDOHC_00558 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NPDJDOHC_00559 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPDJDOHC_00560 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPDJDOHC_00561 9.82e-298 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NPDJDOHC_00562 8.01e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NPDJDOHC_00563 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NPDJDOHC_00564 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPDJDOHC_00565 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPDJDOHC_00566 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NPDJDOHC_00567 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPDJDOHC_00568 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NPDJDOHC_00569 7.41e-97 ylxL - - - - - - -
NPDJDOHC_00570 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPDJDOHC_00571 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NPDJDOHC_00572 1.45e-143 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NPDJDOHC_00573 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NPDJDOHC_00574 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NPDJDOHC_00575 4.97e-249 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NPDJDOHC_00576 5.68e-203 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NPDJDOHC_00577 3.37e-251 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NPDJDOHC_00578 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NPDJDOHC_00579 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NPDJDOHC_00580 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NPDJDOHC_00581 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NPDJDOHC_00582 1.48e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NPDJDOHC_00583 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NPDJDOHC_00584 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NPDJDOHC_00585 1.08e-250 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NPDJDOHC_00586 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NPDJDOHC_00587 6.59e-81 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NPDJDOHC_00588 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NPDJDOHC_00589 1.54e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NPDJDOHC_00590 1.72e-266 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NPDJDOHC_00591 3.43e-89 ylxF - - S - - - MgtE intracellular N domain
NPDJDOHC_00592 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NPDJDOHC_00593 5.19e-309 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NPDJDOHC_00594 4.35e-126 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NPDJDOHC_00595 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NPDJDOHC_00596 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NPDJDOHC_00597 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NPDJDOHC_00598 2.63e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NPDJDOHC_00599 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NPDJDOHC_00600 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NPDJDOHC_00601 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPDJDOHC_00602 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPDJDOHC_00603 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NPDJDOHC_00604 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPDJDOHC_00605 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPDJDOHC_00606 4.8e-221 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NPDJDOHC_00607 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NPDJDOHC_00608 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NPDJDOHC_00609 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NPDJDOHC_00610 0.0 ylqG - - - - - - -
NPDJDOHC_00611 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPDJDOHC_00612 5.09e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPDJDOHC_00613 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPDJDOHC_00614 2.93e-178 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NPDJDOHC_00615 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPDJDOHC_00616 3.41e-80 ylqD - - S - - - YlqD protein
NPDJDOHC_00617 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NPDJDOHC_00618 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NPDJDOHC_00619 1.47e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPDJDOHC_00620 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPDJDOHC_00621 1.34e-185 - - - S - - - Phosphotransferase enzyme family
NPDJDOHC_00622 2.28e-225 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPDJDOHC_00623 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NPDJDOHC_00624 3.02e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPDJDOHC_00625 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPDJDOHC_00626 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NPDJDOHC_00627 3.22e-219 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NPDJDOHC_00628 7.71e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPDJDOHC_00629 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NPDJDOHC_00630 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPDJDOHC_00631 4.14e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NPDJDOHC_00632 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NPDJDOHC_00633 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NPDJDOHC_00634 3.65e-78 yloU - - S - - - protein conserved in bacteria
NPDJDOHC_00635 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NPDJDOHC_00636 6.68e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NPDJDOHC_00637 6.15e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NPDJDOHC_00638 1.08e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPDJDOHC_00639 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NPDJDOHC_00640 5.2e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NPDJDOHC_00641 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NPDJDOHC_00642 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPDJDOHC_00643 4.76e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPDJDOHC_00644 5e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPDJDOHC_00645 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPDJDOHC_00646 9.26e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPDJDOHC_00647 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPDJDOHC_00648 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NPDJDOHC_00649 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NPDJDOHC_00650 1.51e-198 yloC - - S - - - stress-induced protein
NPDJDOHC_00651 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NPDJDOHC_00652 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NPDJDOHC_00653 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NPDJDOHC_00654 1.76e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NPDJDOHC_00655 2.06e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NPDJDOHC_00656 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NPDJDOHC_00657 4.53e-286 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NPDJDOHC_00658 8.54e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NPDJDOHC_00659 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NPDJDOHC_00661 2.2e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPDJDOHC_00662 3.66e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPDJDOHC_00663 7.67e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPDJDOHC_00664 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NPDJDOHC_00665 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NPDJDOHC_00666 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NPDJDOHC_00667 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPDJDOHC_00668 6.51e-217 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NPDJDOHC_00669 3.42e-297 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NPDJDOHC_00670 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPDJDOHC_00671 2.65e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NPDJDOHC_00672 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPDJDOHC_00673 6.48e-87 ylyA - - T - - - COG1734 DnaK suppressor protein
NPDJDOHC_00674 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPDJDOHC_00675 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NPDJDOHC_00676 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
NPDJDOHC_00677 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NPDJDOHC_00678 7.98e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPDJDOHC_00679 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NPDJDOHC_00680 5.76e-207 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NPDJDOHC_00681 7.13e-52 ylmC - - S - - - sporulation protein
NPDJDOHC_00682 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NPDJDOHC_00683 2.06e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NPDJDOHC_00684 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPDJDOHC_00685 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPDJDOHC_00686 2.02e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NPDJDOHC_00687 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NPDJDOHC_00689 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPDJDOHC_00690 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPDJDOHC_00691 9.33e-180 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPDJDOHC_00692 1.17e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NPDJDOHC_00693 5.69e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPDJDOHC_00694 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NPDJDOHC_00695 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPDJDOHC_00696 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPDJDOHC_00697 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPDJDOHC_00698 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NPDJDOHC_00699 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NPDJDOHC_00700 2.4e-68 ftsL - - D - - - Essential cell division protein
NPDJDOHC_00701 3.5e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPDJDOHC_00702 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NPDJDOHC_00703 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NPDJDOHC_00704 6.13e-213 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPDJDOHC_00705 1.38e-117 ylbP - - K - - - n-acetyltransferase
NPDJDOHC_00706 1.33e-112 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NPDJDOHC_00707 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NPDJDOHC_00708 1.7e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NPDJDOHC_00709 1.34e-297 ylbM - - S - - - Belongs to the UPF0348 family
NPDJDOHC_00710 5.31e-241 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NPDJDOHC_00711 1.23e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NPDJDOHC_00712 1.02e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NPDJDOHC_00713 1.01e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPDJDOHC_00714 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NPDJDOHC_00716 2.78e-57 ylbG - - S - - - UPF0298 protein
NPDJDOHC_00717 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
NPDJDOHC_00718 1.73e-48 ylbE - - S - - - YlbE-like protein
NPDJDOHC_00719 1.52e-89 ylbD - - S - - - Putative coat protein
NPDJDOHC_00720 2.8e-255 ylbC - - S - - - protein with SCP PR1 domains
NPDJDOHC_00721 3.35e-96 ylbB - - T - - - COG0517 FOG CBS domain
NPDJDOHC_00722 1.75e-80 ylbA - - S - - - YugN-like family
NPDJDOHC_00723 5.32e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NPDJDOHC_00724 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NPDJDOHC_00725 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NPDJDOHC_00726 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPDJDOHC_00727 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NPDJDOHC_00728 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPDJDOHC_00729 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NPDJDOHC_00730 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NPDJDOHC_00731 1.05e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NPDJDOHC_00732 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
NPDJDOHC_00733 6.57e-224 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NPDJDOHC_00734 3.02e-111 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NPDJDOHC_00735 8.09e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NPDJDOHC_00736 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPDJDOHC_00737 6.78e-46 ylaI - - S - - - protein conserved in bacteria
NPDJDOHC_00738 2.44e-65 - - - S - - - YlaH-like protein
NPDJDOHC_00739 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NPDJDOHC_00740 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
NPDJDOHC_00741 3.48e-63 ylaE - - - - - - -
NPDJDOHC_00743 8.11e-121 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NPDJDOHC_00744 5.38e-61 ylaB - - - - - - -
NPDJDOHC_00745 5.66e-184 - - - - - - - -
NPDJDOHC_00746 2.3e-255 ylaA - - - - - - -
NPDJDOHC_00747 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NPDJDOHC_00748 1.3e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
NPDJDOHC_00749 9.88e-197 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NPDJDOHC_00750 3.33e-33 ykzI - - - - - - -
NPDJDOHC_00751 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
NPDJDOHC_00752 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
NPDJDOHC_00753 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NPDJDOHC_00754 4.87e-193 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NPDJDOHC_00755 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NPDJDOHC_00756 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPDJDOHC_00757 7.27e-302 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPDJDOHC_00758 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPDJDOHC_00759 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPDJDOHC_00760 8.9e-272 - - - V - - - Beta-lactamase
NPDJDOHC_00761 0.0 - - - IQ - - - Phosphopantetheine attachment site
NPDJDOHC_00762 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00763 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00764 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00765 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00766 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
NPDJDOHC_00767 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_00768 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NPDJDOHC_00769 1.88e-136 ykyA - - L - - - Putative cell-wall binding lipoprotein
NPDJDOHC_00770 1.08e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NPDJDOHC_00771 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPDJDOHC_00772 5.48e-190 ykrA - - S - - - hydrolases of the HAD superfamily
NPDJDOHC_00773 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
NPDJDOHC_00774 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPDJDOHC_00775 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NPDJDOHC_00776 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NPDJDOHC_00777 1.58e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NPDJDOHC_00778 5.87e-313 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NPDJDOHC_00779 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NPDJDOHC_00780 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NPDJDOHC_00781 6.35e-18 - - - S - - - Uncharacterized protein YkpC
NPDJDOHC_00782 2.95e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NPDJDOHC_00783 1.6e-216 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPDJDOHC_00784 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPDJDOHC_00785 4.47e-51 ykoA - - - - - - -
NPDJDOHC_00786 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NPDJDOHC_00787 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NPDJDOHC_00788 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NPDJDOHC_00789 1.18e-172 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_00790 1.09e-271 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NPDJDOHC_00791 2.9e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_00792 2e-246 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NPDJDOHC_00793 7.2e-144 yknW - - S - - - Yip1 domain
NPDJDOHC_00794 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NPDJDOHC_00795 7.17e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NPDJDOHC_00796 3.21e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NPDJDOHC_00797 1.29e-314 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NPDJDOHC_00798 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NPDJDOHC_00799 1.72e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NPDJDOHC_00800 2.53e-218 yknT - - - ko:K06437 - ko00000 -
NPDJDOHC_00801 7.46e-127 rok - - K - - - Repressor of ComK
NPDJDOHC_00802 8.45e-106 ykuV - - CO - - - thiol-disulfide
NPDJDOHC_00803 1.54e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NPDJDOHC_00804 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
NPDJDOHC_00805 2.39e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPDJDOHC_00806 2.49e-130 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPDJDOHC_00807 3.19e-105 fld - - C ko:K03839 - ko00000 Flavodoxin
NPDJDOHC_00808 2.47e-222 ykuO - - - - - - -
NPDJDOHC_00809 3.15e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
NPDJDOHC_00810 1.32e-215 ccpC - - K - - - Transcriptional regulator
NPDJDOHC_00811 8.55e-99 ykuL - - S - - - CBS domain
NPDJDOHC_00812 4.54e-37 ykzF - - S - - - Antirepressor AbbA
NPDJDOHC_00813 5.29e-121 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
NPDJDOHC_00814 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
NPDJDOHC_00815 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
NPDJDOHC_00816 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_00817 1.02e-203 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NPDJDOHC_00818 8.88e-117 ykuD - - S - - - protein conserved in bacteria
NPDJDOHC_00819 9.69e-310 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_00820 5.07e-108 ykyB - - S - - - YkyB-like protein
NPDJDOHC_00821 4.07e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NPDJDOHC_00822 6.38e-15 - - - - - - - -
NPDJDOHC_00823 2.81e-276 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NPDJDOHC_00824 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_00825 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NPDJDOHC_00826 2.37e-177 ykwD - - J - - - protein with SCP PR1 domains
NPDJDOHC_00827 4.13e-86 - - - - - - - -
NPDJDOHC_00828 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NPDJDOHC_00829 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NPDJDOHC_00830 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NPDJDOHC_00831 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_00832 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPDJDOHC_00833 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NPDJDOHC_00834 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_00835 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NPDJDOHC_00836 2.12e-226 ykvZ - - K - - - Transcriptional regulator
NPDJDOHC_00838 9.91e-265 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NPDJDOHC_00839 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NPDJDOHC_00840 6.28e-116 stoA - - CO - - - thiol-disulfide
NPDJDOHC_00841 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPDJDOHC_00842 1.77e-143 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NPDJDOHC_00843 7.17e-39 - - - - - - - -
NPDJDOHC_00844 5.43e-35 ykvS - - S - - - protein conserved in bacteria
NPDJDOHC_00845 4.38e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
NPDJDOHC_00846 3.24e-44 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NPDJDOHC_00847 1.89e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NPDJDOHC_00848 6.24e-78 ykvN - - K - - - Transcriptional regulator
NPDJDOHC_00850 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NPDJDOHC_00851 1.76e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NPDJDOHC_00852 8.23e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NPDJDOHC_00853 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NPDJDOHC_00854 2.05e-257 - - - - - - - -
NPDJDOHC_00855 6.6e-233 ykvI - - S - - - membrane
NPDJDOHC_00856 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NPDJDOHC_00857 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NPDJDOHC_00858 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NPDJDOHC_00859 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NPDJDOHC_00860 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NPDJDOHC_00862 6.37e-125 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NPDJDOHC_00863 2.33e-149 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NPDJDOHC_00864 1.4e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NPDJDOHC_00865 4.05e-291 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NPDJDOHC_00866 7.65e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NPDJDOHC_00867 9.87e-194 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPDJDOHC_00868 1.04e-288 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NPDJDOHC_00869 9.34e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NPDJDOHC_00871 1.17e-116 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPDJDOHC_00872 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_00873 4.95e-246 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NPDJDOHC_00874 3.07e-32 ykzE - - - - - - -
NPDJDOHC_00875 1.74e-149 - - - S - - - Protein of unknown function (DUF421)
NPDJDOHC_00876 1.62e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NPDJDOHC_00877 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NPDJDOHC_00878 6.86e-163 ykrK - - S - - - Domain of unknown function (DUF1836)
NPDJDOHC_00879 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NPDJDOHC_00880 2.53e-250 ykrI - - S - - - Anti-sigma factor N-terminus
NPDJDOHC_00881 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPDJDOHC_00882 3.54e-174 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NPDJDOHC_00883 1.43e-131 ykoX - - S - - - membrane-associated protein
NPDJDOHC_00884 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NPDJDOHC_00885 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NPDJDOHC_00886 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
NPDJDOHC_00887 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NPDJDOHC_00888 5.25e-37 ykoL - - - - - - -
NPDJDOHC_00889 1.11e-23 - - - - - - - -
NPDJDOHC_00890 1.23e-69 tnrA - - K - - - transcriptional
NPDJDOHC_00891 8.66e-310 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NPDJDOHC_00893 1.13e-312 ydhD - - M - - - Glycosyl hydrolase
NPDJDOHC_00894 1.19e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NPDJDOHC_00895 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_00896 6.53e-171 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NPDJDOHC_00897 5.66e-193 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPDJDOHC_00898 1.09e-227 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NPDJDOHC_00899 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NPDJDOHC_00900 2.53e-161 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NPDJDOHC_00901 4.16e-279 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_00902 1.72e-192 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
NPDJDOHC_00903 1.82e-277 - - - M - - - Glycosyl transferase family 2
NPDJDOHC_00905 1.83e-86 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NPDJDOHC_00906 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
NPDJDOHC_00907 7.54e-115 ohrR - - K - - - COG1846 Transcriptional regulators
NPDJDOHC_00908 5.88e-94 ohrA - - O - - - Organic hydroperoxide resistance protein
NPDJDOHC_00909 1.37e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPDJDOHC_00910 3.73e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPDJDOHC_00911 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NPDJDOHC_00912 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NPDJDOHC_00913 7.06e-70 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NPDJDOHC_00914 1.34e-132 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPDJDOHC_00915 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
NPDJDOHC_00916 4.37e-206 ykgA - - E - - - Amidinotransferase
NPDJDOHC_00917 1.46e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NPDJDOHC_00918 1.39e-232 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_00919 2.89e-222 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPDJDOHC_00920 4.18e-262 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NPDJDOHC_00921 5.87e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NPDJDOHC_00922 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NPDJDOHC_00923 6.75e-245 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_00924 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPDJDOHC_00925 2.4e-205 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPDJDOHC_00926 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NPDJDOHC_00928 0.0 yubD - - P - - - Major Facilitator Superfamily
NPDJDOHC_00929 2.36e-279 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPDJDOHC_00931 6.62e-231 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NPDJDOHC_00932 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPDJDOHC_00933 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NPDJDOHC_00934 2.3e-312 steT - - E ko:K03294 - ko00000 amino acid
NPDJDOHC_00935 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NPDJDOHC_00936 8.61e-227 pit - - P ko:K03306 - ko00000 phosphate transporter
NPDJDOHC_00937 2.79e-174 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NPDJDOHC_00938 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NPDJDOHC_00939 5.16e-217 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NPDJDOHC_00940 4.7e-52 xhlB - - S - - - SPP1 phage holin
NPDJDOHC_00941 3.87e-51 xhlA - - S - - - Haemolysin XhlA
NPDJDOHC_00942 7.18e-184 xepA - - - - - - -
NPDJDOHC_00943 5.6e-41 xkdX - - - - - - -
NPDJDOHC_00945 9.95e-50 - - - - - - - -
NPDJDOHC_00946 1.24e-47 xtmA - - - ko:K07474 - ko00000 -
NPDJDOHC_00947 1.07e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NPDJDOHC_00951 9.14e-198 xkdC - - L - - - Bacterial dnaA protein
NPDJDOHC_00952 1.69e-22 xkdB - - K - - - sequence-specific DNA binding
NPDJDOHC_00954 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
NPDJDOHC_00955 6.51e-145 xkdA - - E - - - IrrE N-terminal-like domain
NPDJDOHC_00956 7.87e-144 yjqB - - S - - - phage-related replication protein
NPDJDOHC_00957 9.51e-81 yjqA - - S - - - Bacterial PH domain
NPDJDOHC_00958 8.26e-222 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NPDJDOHC_00960 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NPDJDOHC_00961 4.32e-105 yjoA - - S - - - DinB family
NPDJDOHC_00962 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NPDJDOHC_00963 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NPDJDOHC_00964 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
NPDJDOHC_00965 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NPDJDOHC_00966 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
NPDJDOHC_00967 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NPDJDOHC_00968 7.49e-281 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NPDJDOHC_00969 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NPDJDOHC_00970 8.91e-121 yjlB - - S - - - Cupin domain
NPDJDOHC_00971 7.42e-230 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NPDJDOHC_00972 4.76e-170 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_00973 3.55e-159 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NPDJDOHC_00974 1.43e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NPDJDOHC_00975 1.73e-40 - - - - - - - -
NPDJDOHC_00976 2.64e-287 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NPDJDOHC_00977 7.66e-292 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NPDJDOHC_00978 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
NPDJDOHC_00979 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NPDJDOHC_00980 6.05e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
NPDJDOHC_00981 1.87e-93 yjgA - - T - - - Protein of unknown function (DUF2809)
NPDJDOHC_00982 1.91e-31 yjfB - - S - - - Putative motility protein
NPDJDOHC_00984 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NPDJDOHC_00986 2.14e-192 - - - N - - - Kelch motif
NPDJDOHC_00987 1.29e-164 - - - S - - - Haloacid dehalogenase-like hydrolase
NPDJDOHC_00988 1.02e-179 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NPDJDOHC_00989 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NPDJDOHC_00990 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_00991 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPDJDOHC_00992 3.42e-280 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPDJDOHC_00993 3.61e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NPDJDOHC_00994 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NPDJDOHC_00995 8.39e-285 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NPDJDOHC_00996 3.68e-107 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NPDJDOHC_00997 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
NPDJDOHC_00998 2.2e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NPDJDOHC_00999 1.13e-217 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
NPDJDOHC_01002 1.7e-176 - - - - - - - -
NPDJDOHC_01005 1.18e-122 - - - - - - - -
NPDJDOHC_01006 0.0 - - - S - - - Bacterial EndoU nuclease
NPDJDOHC_01007 1.05e-75 - - - - - - - -
NPDJDOHC_01008 6.79e-06 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
NPDJDOHC_01009 2.43e-18 - - - - - - - -
NPDJDOHC_01011 1.76e-108 - - - - - - - -
NPDJDOHC_01013 0.0 - - - S - - - Bacterial EndoU nuclease
NPDJDOHC_01014 1.14e-41 - - - - - - - -
NPDJDOHC_01016 2.82e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NPDJDOHC_01017 3.37e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NPDJDOHC_01018 8.63e-165 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NPDJDOHC_01019 2.43e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NPDJDOHC_01020 3.66e-98 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPDJDOHC_01021 4.32e-48 - - - K - - - SpoVT / AbrB like domain
NPDJDOHC_01022 2.48e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NPDJDOHC_01023 1.13e-160 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NPDJDOHC_01024 1.57e-185 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
NPDJDOHC_01025 1.49e-49 - - - - - - - -
NPDJDOHC_01026 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NPDJDOHC_01027 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
NPDJDOHC_01028 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NPDJDOHC_01030 1.24e-74 yjcA - - S - - - Protein of unknown function (DUF1360)
NPDJDOHC_01031 3.02e-74 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
NPDJDOHC_01032 1.98e-36 cotW - - - ko:K06341 - ko00000 -
NPDJDOHC_01033 2.33e-103 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NPDJDOHC_01034 5.2e-122 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NPDJDOHC_01035 1.79e-109 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NPDJDOHC_01036 2.9e-126 yjbX - - S - - - Spore coat protein
NPDJDOHC_01037 1.68e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NPDJDOHC_01038 4.49e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NPDJDOHC_01039 8.18e-243 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NPDJDOHC_01040 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NPDJDOHC_01041 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
NPDJDOHC_01042 6.85e-279 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NPDJDOHC_01043 8.09e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NPDJDOHC_01044 4.88e-178 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NPDJDOHC_01045 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPDJDOHC_01046 5.48e-186 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NPDJDOHC_01047 8.54e-214 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NPDJDOHC_01048 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPDJDOHC_01049 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NPDJDOHC_01050 3.5e-81 yjbL - - S - - - Belongs to the UPF0738 family
NPDJDOHC_01051 4.41e-131 yjbK - - S - - - protein conserved in bacteria
NPDJDOHC_01052 1.32e-153 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPDJDOHC_01053 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NPDJDOHC_01054 1.49e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NPDJDOHC_01055 3.14e-27 - - - - - - - -
NPDJDOHC_01056 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NPDJDOHC_01057 4.36e-286 coiA - - S ko:K06198 - ko00000 Competence protein
NPDJDOHC_01058 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NPDJDOHC_01059 1.18e-142 yjbE - - P - - - Integral membrane protein TerC family
NPDJDOHC_01060 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPDJDOHC_01061 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPDJDOHC_01062 1.5e-299 - - - S - - - Putative glycosyl hydrolase domain
NPDJDOHC_01063 2.19e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_01064 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_01065 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPDJDOHC_01066 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPDJDOHC_01067 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NPDJDOHC_01068 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NPDJDOHC_01069 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
NPDJDOHC_01070 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPDJDOHC_01071 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPDJDOHC_01072 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NPDJDOHC_01073 8.8e-239 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_01074 7.17e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_01075 1.84e-190 yjaZ - - O - - - Zn-dependent protease
NPDJDOHC_01076 2.71e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPDJDOHC_01077 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPDJDOHC_01078 2.82e-44 yjzB - - - - - - -
NPDJDOHC_01079 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NPDJDOHC_01080 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NPDJDOHC_01081 2.12e-137 yjaV - - - - - - -
NPDJDOHC_01082 1.4e-181 yjaU - - I - - - carboxylic ester hydrolase activity
NPDJDOHC_01083 5.24e-33 yjzD - - S - - - Protein of unknown function (DUF2929)
NPDJDOHC_01084 7.21e-39 yjzC - - S - - - YjzC-like protein
NPDJDOHC_01085 3.02e-227 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPDJDOHC_01086 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NPDJDOHC_01087 1.69e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NPDJDOHC_01088 1.19e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NPDJDOHC_01089 1.88e-177 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NPDJDOHC_01090 5.39e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NPDJDOHC_01091 9.02e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NPDJDOHC_01092 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
NPDJDOHC_01093 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NPDJDOHC_01094 1.42e-106 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NPDJDOHC_01095 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NPDJDOHC_01096 9.1e-188 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NPDJDOHC_01097 1.52e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NPDJDOHC_01098 1.49e-11 - - - - - - - -
NPDJDOHC_01099 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
NPDJDOHC_01100 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
NPDJDOHC_01101 1.61e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NPDJDOHC_01102 9.52e-204 yitS - - S - - - protein conserved in bacteria
NPDJDOHC_01104 5.82e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NPDJDOHC_01105 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NPDJDOHC_01106 9.67e-225 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
NPDJDOHC_01107 1.59e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NPDJDOHC_01108 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NPDJDOHC_01109 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NPDJDOHC_01110 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
NPDJDOHC_01111 1.42e-113 yisX - - S - - - Pentapeptide repeats (9 copies)
NPDJDOHC_01112 5.37e-117 yisT - - S - - - DinB family
NPDJDOHC_01113 4.22e-209 yisR - - K - - - Transcriptional regulator
NPDJDOHC_01114 2.25e-312 yisQ - - V - - - Mate efflux family protein
NPDJDOHC_01115 1.19e-174 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NPDJDOHC_01116 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NPDJDOHC_01117 2.35e-127 yisN - - S - - - Protein of unknown function (DUF2777)
NPDJDOHC_01118 2.22e-78 yisL - - S - - - UPF0344 protein
NPDJDOHC_01119 1.13e-220 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NPDJDOHC_01120 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
NPDJDOHC_01121 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NPDJDOHC_01122 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
NPDJDOHC_01123 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NPDJDOHC_01124 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NPDJDOHC_01125 1.67e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NPDJDOHC_01126 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NPDJDOHC_01127 2.64e-67 yisB - - V - - - COG1403 Restriction endonuclease
NPDJDOHC_01128 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NPDJDOHC_01129 5.72e-284 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPDJDOHC_01130 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NPDJDOHC_01131 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NPDJDOHC_01132 1.81e-162 ydfS - - S - - - Protein of unknown function (DUF421)
NPDJDOHC_01133 4.38e-123 yhjR - - S - - - Rubrerythrin
NPDJDOHC_01134 2.72e-142 - - - K - - - QacR-like protein, C-terminal region
NPDJDOHC_01135 2.27e-269 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_01136 4.19e-263 yhjN - - S ko:K07120 - ko00000 membrane
NPDJDOHC_01137 1.03e-123 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NPDJDOHC_01138 0.0 yhjG - - CH - - - FAD binding domain
NPDJDOHC_01139 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NPDJDOHC_01140 2.83e-145 yhjE - - S - - - SNARE associated Golgi protein
NPDJDOHC_01141 4.12e-79 yhjD - - - - - - -
NPDJDOHC_01142 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
NPDJDOHC_01143 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPDJDOHC_01144 2.2e-68 - - - S - - - Belongs to the UPF0145 family
NPDJDOHC_01145 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
NPDJDOHC_01146 8e-166 yrpD - - S - - - Domain of unknown function, YrpD
NPDJDOHC_01147 3.6e-122 - - - S - - - MepB protein
NPDJDOHC_01148 8.17e-90 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NPDJDOHC_01149 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NPDJDOHC_01150 7.64e-142 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NPDJDOHC_01151 5.7e-44 yhzC - - S - - - IDEAL
NPDJDOHC_01152 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_01153 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NPDJDOHC_01154 1.18e-278 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NPDJDOHC_01155 1.86e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NPDJDOHC_01156 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NPDJDOHC_01157 8.08e-259 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NPDJDOHC_01158 4.42e-136 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NPDJDOHC_01159 2.83e-205 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NPDJDOHC_01160 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NPDJDOHC_01161 1.11e-301 yhfN - - O - - - Peptidase M48
NPDJDOHC_01162 2.38e-86 yhfM - - - - - - -
NPDJDOHC_01163 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NPDJDOHC_01164 1.14e-145 yhfK - - GM - - - NmrA-like family
NPDJDOHC_01165 3.9e-243 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NPDJDOHC_01166 1.7e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NPDJDOHC_01167 3.36e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPDJDOHC_01168 5.41e-253 yhfE - - G - - - peptidase M42
NPDJDOHC_01170 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPDJDOHC_01171 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NPDJDOHC_01172 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_01173 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NPDJDOHC_01174 7.76e-233 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NPDJDOHC_01175 2.2e-260 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NPDJDOHC_01176 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NPDJDOHC_01177 4.58e-119 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NPDJDOHC_01178 4.16e-313 yhfA - - C - - - membrane
NPDJDOHC_01179 2.26e-288 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NPDJDOHC_01180 6.35e-164 ecsC - - S - - - EcsC protein family
NPDJDOHC_01181 7.81e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NPDJDOHC_01182 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NPDJDOHC_01183 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NPDJDOHC_01184 5.28e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NPDJDOHC_01185 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
NPDJDOHC_01186 2.55e-24 - - - - - - - -
NPDJDOHC_01187 4.74e-55 yhaH - - S - - - YtxH-like protein
NPDJDOHC_01188 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NPDJDOHC_01189 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
NPDJDOHC_01190 1.29e-123 yhaK - - S - - - Putative zincin peptidase
NPDJDOHC_01191 5.57e-187 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPDJDOHC_01192 3.48e-44 yhaL - - S - - - Sporulation protein YhaL
NPDJDOHC_01193 4.29e-227 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NPDJDOHC_01194 0.0 yhaN - - L - - - AAA domain
NPDJDOHC_01195 9.48e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NPDJDOHC_01196 3.55e-279 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NPDJDOHC_01197 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_01198 5.99e-21 - - - S - - - YhzD-like protein
NPDJDOHC_01199 6.34e-179 yhaR - - I - - - enoyl-CoA hydratase
NPDJDOHC_01201 4.58e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NPDJDOHC_01202 2.43e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NPDJDOHC_01203 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
NPDJDOHC_01204 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NPDJDOHC_01205 1.03e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NPDJDOHC_01206 1.82e-260 yhaZ - - L - - - DNA alkylation repair enzyme
NPDJDOHC_01207 9.85e-72 yheA - - S - - - Belongs to the UPF0342 family
NPDJDOHC_01208 2.01e-266 yheB - - S - - - Belongs to the UPF0754 family
NPDJDOHC_01209 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
NPDJDOHC_01210 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
NPDJDOHC_01211 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
NPDJDOHC_01212 1.15e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NPDJDOHC_01214 6.96e-145 yheG - - GM - - - NAD(P)H-binding
NPDJDOHC_01215 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NPDJDOHC_01216 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NPDJDOHC_01218 4.31e-111 - - - T - - - universal stress protein
NPDJDOHC_01219 2.29e-125 ymcC - - S - - - Membrane
NPDJDOHC_01220 1.22e-114 pksA - - K - - - Transcriptional regulator
NPDJDOHC_01221 1.24e-199 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NPDJDOHC_01222 1.46e-202 nodB1 - - G - - - deacetylase
NPDJDOHC_01223 7.18e-181 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NPDJDOHC_01224 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NPDJDOHC_01225 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
NPDJDOHC_01226 1.97e-169 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NPDJDOHC_01227 4.27e-89 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPDJDOHC_01228 2.12e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPDJDOHC_01229 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NPDJDOHC_01230 2.84e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPDJDOHC_01231 1.47e-288 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NPDJDOHC_01232 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NPDJDOHC_01233 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NPDJDOHC_01234 1.59e-142 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NPDJDOHC_01235 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NPDJDOHC_01236 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
NPDJDOHC_01237 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
NPDJDOHC_01238 1.78e-268 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NPDJDOHC_01239 8.9e-317 yhdG - - E ko:K03294 - ko00000 amino acid
NPDJDOHC_01240 2.73e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_01241 5.96e-264 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NPDJDOHC_01242 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_01243 5.53e-178 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NPDJDOHC_01244 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NPDJDOHC_01245 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NPDJDOHC_01246 0.0 ygxB - - M - - - Conserved TM helix
NPDJDOHC_01247 3.25e-97 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NPDJDOHC_01248 1.27e-298 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NPDJDOHC_01249 1.46e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
NPDJDOHC_01250 6.98e-53 yhdB - - S - - - YhdB-like protein
NPDJDOHC_01251 1.76e-118 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NPDJDOHC_01252 3.15e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPDJDOHC_01253 2.18e-267 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_01254 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NPDJDOHC_01255 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NPDJDOHC_01256 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPDJDOHC_01257 2.83e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NPDJDOHC_01258 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NPDJDOHC_01259 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPDJDOHC_01260 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPDJDOHC_01261 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
NPDJDOHC_01262 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
NPDJDOHC_01263 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
NPDJDOHC_01264 5.19e-222 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NPDJDOHC_01265 8.19e-140 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NPDJDOHC_01266 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NPDJDOHC_01267 8.36e-154 yhcQ - - M - - - Spore coat protein
NPDJDOHC_01268 1.72e-209 yhcP - - - - - - -
NPDJDOHC_01269 2.3e-123 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPDJDOHC_01270 1.99e-81 yhcM - - - - - - -
NPDJDOHC_01271 9.51e-296 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPDJDOHC_01272 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NPDJDOHC_01273 2.13e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NPDJDOHC_01274 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NPDJDOHC_01275 3.3e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPDJDOHC_01276 2.35e-215 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_01277 6.21e-163 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_01278 1.64e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_01279 2.33e-66 - - - - - - - -
NPDJDOHC_01280 1.41e-72 yhcC - - - - - - -
NPDJDOHC_01281 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NPDJDOHC_01282 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NPDJDOHC_01283 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NPDJDOHC_01284 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NPDJDOHC_01285 4.34e-281 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NPDJDOHC_01286 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NPDJDOHC_01287 1.23e-07 - - - - - - - -
NPDJDOHC_01288 2.47e-95 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NPDJDOHC_01289 1.49e-87 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NPDJDOHC_01290 3.4e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
NPDJDOHC_01291 8.36e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPDJDOHC_01292 2.13e-226 yhbB - - S - - - Putative amidase domain
NPDJDOHC_01293 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NPDJDOHC_01294 1.64e-148 yhzB - - S - - - B3/4 domain
NPDJDOHC_01296 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_01297 3.16e-107 ygaO - - - - - - -
NPDJDOHC_01298 1.18e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPDJDOHC_01299 7.7e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NPDJDOHC_01300 3.01e-188 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NPDJDOHC_01301 4.48e-232 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NPDJDOHC_01302 1.1e-180 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NPDJDOHC_01303 2.52e-238 - - - S ko:K07045 - ko00000 Amidohydrolase
NPDJDOHC_01304 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NPDJDOHC_01307 0.0 ygaK - - C - - - Berberine and berberine like
NPDJDOHC_01308 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NPDJDOHC_01309 2.07e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NPDJDOHC_01310 0.0 - - - C - - - Na+/H+ antiporter family
NPDJDOHC_01327 1.46e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NPDJDOHC_01328 1.6e-279 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NPDJDOHC_01329 1.68e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NPDJDOHC_01330 4.6e-108 yuaE - - S - - - DinB superfamily
NPDJDOHC_01331 1.67e-141 - - - S - - - MOSC domain
NPDJDOHC_01332 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NPDJDOHC_01333 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NPDJDOHC_01334 3.51e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NPDJDOHC_01335 2.03e-122 yuaB - - - - - - -
NPDJDOHC_01336 2.6e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NPDJDOHC_01337 1.62e-194 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPDJDOHC_01338 1.52e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NPDJDOHC_01339 5.74e-161 - - - G - - - Cupin
NPDJDOHC_01340 1.64e-72 yjcN - - - - - - -
NPDJDOHC_01342 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NPDJDOHC_01343 6.02e-252 yubA - - S - - - transporter activity
NPDJDOHC_01344 2.84e-239 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NPDJDOHC_01345 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NPDJDOHC_01346 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NPDJDOHC_01347 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NPDJDOHC_01348 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NPDJDOHC_01349 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NPDJDOHC_01350 3.28e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NPDJDOHC_01351 1.61e-55 - - - - - - - -
NPDJDOHC_01352 6.26e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NPDJDOHC_01353 1.83e-101 yugU - - S - - - Uncharacterised protein family UPF0047
NPDJDOHC_01354 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NPDJDOHC_01355 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NPDJDOHC_01356 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NPDJDOHC_01357 1.24e-22 - - - - - - - -
NPDJDOHC_01358 2.44e-35 mstX - - S - - - Membrane-integrating protein Mistic
NPDJDOHC_01359 8.37e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NPDJDOHC_01360 2.09e-95 yugN - - S - - - YugN-like family
NPDJDOHC_01362 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NPDJDOHC_01363 6.81e-134 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NPDJDOHC_01364 2.15e-152 ycaC - - Q - - - Isochorismatase family
NPDJDOHC_01365 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NPDJDOHC_01366 4.92e-288 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NPDJDOHC_01367 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NPDJDOHC_01368 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NPDJDOHC_01369 2.59e-270 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NPDJDOHC_01370 3.75e-109 alaR - - K - - - Transcriptional regulator
NPDJDOHC_01371 9.89e-201 yugF - - I - - - Hydrolase
NPDJDOHC_01372 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
NPDJDOHC_01373 8.16e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NPDJDOHC_01374 7.71e-294 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_01375 2.05e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NPDJDOHC_01376 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NPDJDOHC_01377 2.25e-264 yuxJ - - EGP - - - Major facilitator superfamily
NPDJDOHC_01378 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NPDJDOHC_01379 1.85e-95 yuxK - - S - - - protein conserved in bacteria
NPDJDOHC_01380 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
NPDJDOHC_01381 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NPDJDOHC_01382 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NPDJDOHC_01383 1.74e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NPDJDOHC_01384 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_01385 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NPDJDOHC_01386 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NPDJDOHC_01388 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NPDJDOHC_01389 5.39e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPDJDOHC_01390 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPDJDOHC_01391 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPDJDOHC_01392 6.08e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPDJDOHC_01393 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPDJDOHC_01394 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NPDJDOHC_01395 1.45e-85 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NPDJDOHC_01396 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPDJDOHC_01397 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_01399 6.39e-199 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
NPDJDOHC_01400 2.66e-11 - - - S - - - DegQ (SacQ) family
NPDJDOHC_01401 7.9e-72 yuzC - - - - - - -
NPDJDOHC_01402 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NPDJDOHC_01403 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPDJDOHC_01404 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NPDJDOHC_01405 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
NPDJDOHC_01406 5.46e-51 yueH - - S - - - YueH-like protein
NPDJDOHC_01407 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NPDJDOHC_01408 1.14e-239 yueF - - S - - - transporter activity
NPDJDOHC_01409 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
NPDJDOHC_01410 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NPDJDOHC_01411 8.67e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_01412 1.38e-102 yueC - - S - - - Family of unknown function (DUF5383)
NPDJDOHC_01413 0.0 yueB - - S - - - type VII secretion protein EsaA
NPDJDOHC_01414 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPDJDOHC_01415 3.38e-277 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NPDJDOHC_01416 9.1e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NPDJDOHC_01417 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
NPDJDOHC_01418 3.81e-294 yukF - - QT - - - Transcriptional regulator
NPDJDOHC_01419 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NPDJDOHC_01420 1.84e-172 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NPDJDOHC_01421 2.82e-48 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NPDJDOHC_01422 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_01423 5.21e-225 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NPDJDOHC_01424 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NPDJDOHC_01425 4.07e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NPDJDOHC_01426 1.1e-174 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_01427 1.53e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
NPDJDOHC_01428 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NPDJDOHC_01429 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NPDJDOHC_01430 2.01e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NPDJDOHC_01431 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NPDJDOHC_01432 2.47e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NPDJDOHC_01433 7.23e-155 yuiC - - S - - - protein conserved in bacteria
NPDJDOHC_01434 8.54e-46 yuiB - - S - - - Putative membrane protein
NPDJDOHC_01435 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NPDJDOHC_01436 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NPDJDOHC_01438 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPDJDOHC_01439 5.68e-40 - - - - - - - -
NPDJDOHC_01440 5.08e-94 - - - CP - - - Membrane
NPDJDOHC_01441 4.11e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NPDJDOHC_01443 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
NPDJDOHC_01445 5.25e-125 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NPDJDOHC_01446 3.83e-179 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_01447 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NPDJDOHC_01448 5.54e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPDJDOHC_01449 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPDJDOHC_01450 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
NPDJDOHC_01451 1.46e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NPDJDOHC_01452 8.37e-76 yuzD - - S - - - protein conserved in bacteria
NPDJDOHC_01453 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NPDJDOHC_01454 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NPDJDOHC_01455 4.08e-218 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPDJDOHC_01456 1.19e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NPDJDOHC_01457 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NPDJDOHC_01458 5.4e-251 yutH - - S - - - Spore coat protein
NPDJDOHC_01459 2.59e-110 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NPDJDOHC_01460 4.31e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPDJDOHC_01461 3.25e-97 yutE - - S - - - Protein of unknown function DUF86
NPDJDOHC_01462 3.71e-62 yutD - - S - - - protein conserved in bacteria
NPDJDOHC_01463 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NPDJDOHC_01464 1e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NPDJDOHC_01465 2.87e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NPDJDOHC_01466 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NPDJDOHC_01467 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NPDJDOHC_01468 1.54e-218 yunF - - S - - - Protein of unknown function DUF72
NPDJDOHC_01469 7.74e-83 - - - S - - - phosphoglycolate phosphatase activity
NPDJDOHC_01470 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NPDJDOHC_01471 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NPDJDOHC_01472 6.36e-97 - - - - - - - -
NPDJDOHC_01474 4.47e-276 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_01475 2.64e-305 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NPDJDOHC_01476 1.3e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NPDJDOHC_01477 2.46e-218 bsn - - L - - - Ribonuclease
NPDJDOHC_01478 1.41e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_01479 5.89e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NPDJDOHC_01480 2.63e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NPDJDOHC_01481 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NPDJDOHC_01482 5.26e-203 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NPDJDOHC_01483 1.36e-315 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NPDJDOHC_01484 2.84e-239 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NPDJDOHC_01485 2.01e-213 - - - K - - - helix_turn_helix, mercury resistance
NPDJDOHC_01488 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NPDJDOHC_01489 4.91e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NPDJDOHC_01490 7.94e-168 - - - Q - - - ubiE/COQ5 methyltransferase family
NPDJDOHC_01491 2.94e-111 yncE - - S - - - Protein of unknown function (DUF2691)
NPDJDOHC_01492 5.3e-203 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NPDJDOHC_01493 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NPDJDOHC_01494 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NPDJDOHC_01495 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPDJDOHC_01496 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NPDJDOHC_01497 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NPDJDOHC_01498 8.85e-85 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NPDJDOHC_01499 4.46e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NPDJDOHC_01500 1.46e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NPDJDOHC_01501 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPDJDOHC_01502 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
NPDJDOHC_01503 1.64e-72 yusE - - CO - - - Thioredoxin
NPDJDOHC_01504 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NPDJDOHC_01505 7.61e-56 yusG - - S - - - Protein of unknown function (DUF2553)
NPDJDOHC_01506 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NPDJDOHC_01507 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NPDJDOHC_01508 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NPDJDOHC_01509 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NPDJDOHC_01510 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NPDJDOHC_01511 1.12e-216 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NPDJDOHC_01512 2.25e-58 - - - - - - - -
NPDJDOHC_01513 4.46e-72 yusN - - M - - - Coat F domain
NPDJDOHC_01514 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NPDJDOHC_01515 0.0 yusP - - P - - - Major facilitator superfamily
NPDJDOHC_01516 1.57e-89 yusQ - - S - - - Tautomerase enzyme
NPDJDOHC_01517 7.69e-171 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_01518 2.44e-206 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
NPDJDOHC_01519 1.3e-207 - - - K - - - Transcriptional regulator
NPDJDOHC_01520 1.29e-179 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NPDJDOHC_01521 1.78e-242 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPDJDOHC_01522 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
NPDJDOHC_01523 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NPDJDOHC_01524 3.77e-60 - - - S - - - YusW-like protein
NPDJDOHC_01525 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NPDJDOHC_01526 5.7e-199 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_01527 4.66e-105 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NPDJDOHC_01528 8.31e-309 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPDJDOHC_01529 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_01530 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_01531 4.63e-33 - - - - - - - -
NPDJDOHC_01532 3.11e-201 yuxN - - K - - - Transcriptional regulator
NPDJDOHC_01533 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPDJDOHC_01534 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
NPDJDOHC_01535 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NPDJDOHC_01536 1.12e-246 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NPDJDOHC_01537 1.04e-269 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NPDJDOHC_01538 7.15e-140 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPDJDOHC_01539 8.56e-248 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_01540 1.54e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NPDJDOHC_01541 2.12e-194 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NPDJDOHC_01542 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NPDJDOHC_01543 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NPDJDOHC_01544 7.41e-294 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_01545 3.23e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NPDJDOHC_01546 4.6e-290 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NPDJDOHC_01547 8.32e-233 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_01548 1.16e-215 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NPDJDOHC_01549 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_01550 2.28e-220 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NPDJDOHC_01551 0.0 yvrG - - T - - - Histidine kinase
NPDJDOHC_01552 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_01553 1.67e-50 - - - - - - - -
NPDJDOHC_01554 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NPDJDOHC_01555 1.88e-21 - - - S - - - YvrJ protein family
NPDJDOHC_01556 1.08e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NPDJDOHC_01557 7.16e-90 yvrL - - S - - - Regulatory protein YrvL
NPDJDOHC_01558 2.4e-189 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NPDJDOHC_01559 1.17e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_01560 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_01561 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NPDJDOHC_01562 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NPDJDOHC_01563 1.06e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NPDJDOHC_01564 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NPDJDOHC_01565 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NPDJDOHC_01566 6e-215 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NPDJDOHC_01567 2.89e-180 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NPDJDOHC_01568 2.84e-127 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
NPDJDOHC_01569 1.06e-148 yfiK - - K - - - Regulator
NPDJDOHC_01570 4.66e-257 - - - T - - - Histidine kinase
NPDJDOHC_01571 4.97e-220 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NPDJDOHC_01572 3.65e-251 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NPDJDOHC_01573 4.36e-263 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NPDJDOHC_01574 1.77e-200 yvgN - - S - - - reductase
NPDJDOHC_01575 9.69e-114 yvgO - - - - - - -
NPDJDOHC_01576 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NPDJDOHC_01577 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NPDJDOHC_01578 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NPDJDOHC_01579 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NPDJDOHC_01580 2.24e-139 yvgT - - S - - - membrane
NPDJDOHC_01581 2.42e-193 - - - S - - - Metallo-peptidase family M12
NPDJDOHC_01582 1.83e-96 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NPDJDOHC_01583 3.33e-140 bdbD - - O - - - Thioredoxin
NPDJDOHC_01584 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NPDJDOHC_01585 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NPDJDOHC_01586 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
NPDJDOHC_01587 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NPDJDOHC_01588 8.97e-252 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NPDJDOHC_01589 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPDJDOHC_01590 2.17e-209 - - - K - - - Helix-turn-helix XRE-family like proteins
NPDJDOHC_01591 9.17e-284 - - - EGP - - - Major Facilitator Superfamily
NPDJDOHC_01592 9.11e-92 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NPDJDOHC_01593 4.33e-189 - - - S ko:K07045 - ko00000 Amidohydrolase
NPDJDOHC_01594 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDJDOHC_01595 1.49e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
NPDJDOHC_01596 9.08e-235 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDJDOHC_01597 1.56e-181 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NPDJDOHC_01598 1.42e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NPDJDOHC_01599 4.4e-158 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NPDJDOHC_01600 3.16e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NPDJDOHC_01601 7.17e-172 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NPDJDOHC_01602 1.57e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NPDJDOHC_01603 6.64e-211 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
NPDJDOHC_01604 4.79e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDJDOHC_01605 1.1e-70 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NPDJDOHC_01607 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NPDJDOHC_01608 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPDJDOHC_01609 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NPDJDOHC_01610 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NPDJDOHC_01611 1.64e-47 yvzC - - K - - - transcriptional
NPDJDOHC_01612 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NPDJDOHC_01613 4.28e-97 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NPDJDOHC_01614 2.97e-70 yvaP - - K - - - transcriptional
NPDJDOHC_01615 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NPDJDOHC_01616 4.69e-159 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NPDJDOHC_01617 1.44e-180 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NPDJDOHC_01618 3.92e-163 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NPDJDOHC_01619 4.62e-163 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_01620 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NPDJDOHC_01621 6.83e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPDJDOHC_01622 2.39e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NPDJDOHC_01623 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NPDJDOHC_01624 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NPDJDOHC_01625 2.64e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NPDJDOHC_01626 6.83e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPDJDOHC_01627 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NPDJDOHC_01628 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NPDJDOHC_01629 1.01e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NPDJDOHC_01630 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NPDJDOHC_01631 1.32e-157 yvbI - - M - - - Membrane
NPDJDOHC_01632 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NPDJDOHC_01633 1.11e-106 yvbK - - K - - - acetyltransferase
NPDJDOHC_01634 1.14e-271 - - - EGP - - - Major facilitator Superfamily
NPDJDOHC_01635 1.02e-230 - - - - - - - -
NPDJDOHC_01636 1.9e-163 - - - S - - - GlcNAc-PI de-N-acetylase
NPDJDOHC_01637 2.89e-185 - - - C - - - WbqC-like protein family
NPDJDOHC_01638 3.92e-192 - - - M - - - Protein involved in cellulose biosynthesis
NPDJDOHC_01639 1.41e-305 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NPDJDOHC_01640 8.95e-222 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
NPDJDOHC_01641 1.19e-278 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NPDJDOHC_01642 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPDJDOHC_01643 1.12e-308 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NPDJDOHC_01644 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPDJDOHC_01645 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NPDJDOHC_01646 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPDJDOHC_01647 2.8e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NPDJDOHC_01648 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPDJDOHC_01649 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NPDJDOHC_01651 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPDJDOHC_01652 2.33e-262 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NPDJDOHC_01653 5.33e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDJDOHC_01655 9.08e-202 yvbU - - K - - - Transcriptional regulator
NPDJDOHC_01656 2.22e-204 yvbV - - EG - - - EamA-like transporter family
NPDJDOHC_01657 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NPDJDOHC_01658 0.0 - - - - - - - -
NPDJDOHC_01659 1.91e-235 yhjM - - K - - - Transcriptional regulator
NPDJDOHC_01660 1.55e-149 - - - S ko:K07149 - ko00000 Membrane
NPDJDOHC_01661 1.08e-215 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NPDJDOHC_01662 8.05e-197 gntR - - K - - - RpiR family transcriptional regulator
NPDJDOHC_01663 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NPDJDOHC_01664 2.89e-292 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NPDJDOHC_01665 1.23e-173 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPDJDOHC_01666 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NPDJDOHC_01667 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPDJDOHC_01668 4.23e-289 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPDJDOHC_01669 5.36e-157 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NPDJDOHC_01670 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NPDJDOHC_01671 7.14e-313 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NPDJDOHC_01672 9.82e-45 yvfG - - S - - - YvfG protein
NPDJDOHC_01673 7.27e-243 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NPDJDOHC_01674 3.31e-283 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NPDJDOHC_01675 6.08e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NPDJDOHC_01676 9.52e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NPDJDOHC_01677 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPDJDOHC_01678 1.68e-255 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NPDJDOHC_01679 4.18e-263 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NPDJDOHC_01680 2.04e-252 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NPDJDOHC_01681 1.46e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NPDJDOHC_01682 3.27e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NPDJDOHC_01683 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NPDJDOHC_01684 4.01e-283 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NPDJDOHC_01685 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NPDJDOHC_01686 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NPDJDOHC_01687 2.87e-156 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NPDJDOHC_01688 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NPDJDOHC_01689 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NPDJDOHC_01690 1.7e-128 ywjB - - H - - - RibD C-terminal domain
NPDJDOHC_01691 1.84e-146 yyaS - - S ko:K07149 - ko00000 Membrane
NPDJDOHC_01692 1.15e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPDJDOHC_01693 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NPDJDOHC_01695 2.64e-54 - - - S - - - Protein of unknown function (DUF1433)
NPDJDOHC_01696 4.11e-57 - - - I - - - Pfam Lipase (class 3)
NPDJDOHC_01697 2.8e-16 - - - S - - - Protein of unknown function (DUF1433)
NPDJDOHC_01698 0.0 - - - I - - - Pfam Lipase (class 3)
NPDJDOHC_01699 3.92e-47 - - - - - - - -
NPDJDOHC_01701 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NPDJDOHC_01702 2.45e-286 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
NPDJDOHC_01703 4.69e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NPDJDOHC_01704 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPDJDOHC_01705 3.34e-210 yraN - - K - - - Transcriptional regulator
NPDJDOHC_01706 6.58e-276 yraM - - S - - - PrpF protein
NPDJDOHC_01707 0.0 - - - EGP - - - Sugar (and other) transporter
NPDJDOHC_01708 1.32e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NPDJDOHC_01709 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NPDJDOHC_01710 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NPDJDOHC_01711 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NPDJDOHC_01712 2.51e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPDJDOHC_01713 5.54e-105 - - - M - - - Ribonuclease
NPDJDOHC_01714 6.92e-184 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NPDJDOHC_01715 2.76e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NPDJDOHC_01716 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NPDJDOHC_01717 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NPDJDOHC_01718 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NPDJDOHC_01719 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NPDJDOHC_01720 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPDJDOHC_01721 1.86e-204 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NPDJDOHC_01722 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NPDJDOHC_01723 2.02e-247 sasA - - T - - - Histidine kinase
NPDJDOHC_01724 3.99e-158 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_01725 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NPDJDOHC_01726 1.71e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NPDJDOHC_01727 2.39e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NPDJDOHC_01728 4.81e-169 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NPDJDOHC_01729 2.51e-150 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NPDJDOHC_01730 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NPDJDOHC_01731 9.92e-302 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NPDJDOHC_01732 1.83e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NPDJDOHC_01733 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NPDJDOHC_01734 3.56e-178 yvpB - - NU - - - protein conserved in bacteria
NPDJDOHC_01735 1.07e-115 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NPDJDOHC_01736 8.12e-158 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NPDJDOHC_01737 1.84e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPDJDOHC_01738 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPDJDOHC_01739 1.27e-290 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPDJDOHC_01740 9.42e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPDJDOHC_01741 1.05e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NPDJDOHC_01742 1.54e-136 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NPDJDOHC_01743 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NPDJDOHC_01744 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
NPDJDOHC_01745 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NPDJDOHC_01746 5.54e-219 yvlB - - S - - - Putative adhesin
NPDJDOHC_01747 4.87e-66 yvlA - - - - - - -
NPDJDOHC_01748 1.78e-51 yvkN - - - - - - -
NPDJDOHC_01749 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPDJDOHC_01750 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPDJDOHC_01751 2.59e-45 csbA - - S - - - protein conserved in bacteria
NPDJDOHC_01752 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NPDJDOHC_01753 2.32e-144 yvkB - - K - - - Transcriptional regulator
NPDJDOHC_01754 1.45e-298 yvkA - - P - - - -transporter
NPDJDOHC_01755 9.15e-284 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPDJDOHC_01756 4.26e-74 swrA - - S - - - Swarming motility protein
NPDJDOHC_01757 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NPDJDOHC_01758 9.32e-309 ywoF - - P - - - Right handed beta helix region
NPDJDOHC_01759 7.34e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NPDJDOHC_01760 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NPDJDOHC_01761 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NPDJDOHC_01762 4.82e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NPDJDOHC_01763 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPDJDOHC_01764 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPDJDOHC_01765 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPDJDOHC_01766 1.35e-89 - - - - - - - -
NPDJDOHC_01767 1.1e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NPDJDOHC_01768 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NPDJDOHC_01769 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NPDJDOHC_01770 9.78e-173 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPDJDOHC_01771 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NPDJDOHC_01772 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NPDJDOHC_01773 5.9e-110 yviE - - - - - - -
NPDJDOHC_01774 8.44e-209 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NPDJDOHC_01775 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NPDJDOHC_01776 2.2e-105 yvyG - - NOU - - - FlgN protein
NPDJDOHC_01777 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NPDJDOHC_01778 5.47e-98 yvyF - - S - - - flagellar protein
NPDJDOHC_01779 2.13e-101 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NPDJDOHC_01780 2.14e-58 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NPDJDOHC_01781 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NPDJDOHC_01782 8.81e-204 degV - - S - - - protein conserved in bacteria
NPDJDOHC_01783 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPDJDOHC_01784 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NPDJDOHC_01785 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NPDJDOHC_01786 2.6e-240 yvhJ - - K - - - Transcriptional regulator
NPDJDOHC_01787 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NPDJDOHC_01788 1.2e-305 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NPDJDOHC_01789 6.92e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NPDJDOHC_01790 8.95e-151 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NPDJDOHC_01791 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NPDJDOHC_01792 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPDJDOHC_01793 7.03e-289 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NPDJDOHC_01794 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPDJDOHC_01795 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NPDJDOHC_01796 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NPDJDOHC_01797 0.0 lytB - - D - - - Stage II sporulation protein
NPDJDOHC_01798 3.22e-65 - - - - - - - -
NPDJDOHC_01799 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NPDJDOHC_01800 1.88e-272 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPDJDOHC_01801 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NPDJDOHC_01802 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPDJDOHC_01803 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NPDJDOHC_01804 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPDJDOHC_01805 0.0 - - - M - - - Glycosyltransferase like family 2
NPDJDOHC_01806 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NPDJDOHC_01807 6.38e-184 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPDJDOHC_01808 1.57e-280 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPDJDOHC_01809 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPDJDOHC_01810 2.43e-243 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NPDJDOHC_01811 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NPDJDOHC_01812 4.65e-256 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NPDJDOHC_01813 1.09e-274 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NPDJDOHC_01814 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
NPDJDOHC_01815 4.54e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPDJDOHC_01816 9.77e-231 ywtF_2 - - K - - - Transcriptional regulator
NPDJDOHC_01817 3.88e-204 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NPDJDOHC_01818 4.5e-80 yttA - - S - - - Pfam Transposase IS66
NPDJDOHC_01819 2.85e-306 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPDJDOHC_01820 4.04e-29 ywtC - - - - - - -
NPDJDOHC_01821 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NPDJDOHC_01822 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NPDJDOHC_01823 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NPDJDOHC_01824 2.54e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NPDJDOHC_01825 1.08e-247 - - - E - - - Spore germination protein
NPDJDOHC_01826 2.25e-263 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
NPDJDOHC_01827 1.1e-230 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NPDJDOHC_01828 1.77e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPDJDOHC_01829 5.83e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NPDJDOHC_01830 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NPDJDOHC_01831 1.87e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NPDJDOHC_01832 1.2e-208 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NPDJDOHC_01833 2.49e-117 batE - - T - - - Sh3 type 3 domain protein
NPDJDOHC_01834 1.5e-124 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NPDJDOHC_01835 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NPDJDOHC_01836 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NPDJDOHC_01837 5.35e-215 alsR - - K - - - LysR substrate binding domain
NPDJDOHC_01838 1.27e-307 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NPDJDOHC_01839 3.43e-163 ywrJ - - - - - - -
NPDJDOHC_01840 1.22e-192 cotB - - - ko:K06325 - ko00000 -
NPDJDOHC_01841 4.09e-273 cotH - - M ko:K06330 - ko00000 Spore Coat
NPDJDOHC_01842 1.16e-31 - - - - - - - -
NPDJDOHC_01843 6.96e-145 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NPDJDOHC_01844 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NPDJDOHC_01845 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NPDJDOHC_01846 4.38e-134 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NPDJDOHC_01847 8.99e-116 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NPDJDOHC_01848 4.5e-175 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NPDJDOHC_01849 9.61e-121 - - - - - - - -
NPDJDOHC_01850 2.28e-63 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
NPDJDOHC_01851 6.63e-137 - - - S - - - Domain of unknown function (DUF1851)
NPDJDOHC_01852 1.34e-95 - - - S - - - LXG domain of WXG superfamily
NPDJDOHC_01853 4.55e-121 - - - - - - - -
NPDJDOHC_01854 2.05e-66 - - - - - - - -
NPDJDOHC_01855 0.0 ywqJ - - S - - - Pre-toxin TG
NPDJDOHC_01856 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
NPDJDOHC_01859 1.84e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
NPDJDOHC_01860 9.43e-316 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPDJDOHC_01861 7.76e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NPDJDOHC_01862 2.69e-158 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NPDJDOHC_01863 3.53e-152 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NPDJDOHC_01864 1.74e-21 - - - - - - - -
NPDJDOHC_01865 0.0 ywqB - - S - - - SWIM zinc finger
NPDJDOHC_01866 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NPDJDOHC_01867 9.52e-205 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NPDJDOHC_01868 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NPDJDOHC_01869 1.79e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NPDJDOHC_01870 4.49e-82 ywpG - - - - - - -
NPDJDOHC_01871 9.16e-91 ywpF - - S - - - YwpF-like protein
NPDJDOHC_01872 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPDJDOHC_01873 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPDJDOHC_01874 8.07e-259 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NPDJDOHC_01875 1.14e-188 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NPDJDOHC_01876 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NPDJDOHC_01877 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NPDJDOHC_01878 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NPDJDOHC_01879 3.58e-93 ywoH - - K - - - transcriptional
NPDJDOHC_01880 2.89e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_01881 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NPDJDOHC_01882 1.98e-312 ywoD - - EGP - - - Major facilitator superfamily
NPDJDOHC_01883 1.37e-133 yjgF - - Q - - - Isochorismatase family
NPDJDOHC_01884 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NPDJDOHC_01885 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NPDJDOHC_01886 2.09e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NPDJDOHC_01887 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NPDJDOHC_01888 8.06e-96 ywnJ - - S - - - VanZ like family
NPDJDOHC_01889 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NPDJDOHC_01890 4.77e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NPDJDOHC_01892 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
NPDJDOHC_01893 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPDJDOHC_01894 2.4e-80 ywnC - - S - - - Family of unknown function (DUF5362)
NPDJDOHC_01895 6.44e-158 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NPDJDOHC_01896 1.08e-88 ywnA - - K - - - Transcriptional regulator
NPDJDOHC_01897 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NPDJDOHC_01898 1.85e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NPDJDOHC_01899 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NPDJDOHC_01900 2.51e-18 csbD - - K - - - CsbD-like
NPDJDOHC_01901 3.66e-108 ywmF - - S - - - Peptidase M50
NPDJDOHC_01902 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NPDJDOHC_01903 1.31e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NPDJDOHC_01904 1.1e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NPDJDOHC_01906 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NPDJDOHC_01907 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NPDJDOHC_01908 3.47e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NPDJDOHC_01909 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPDJDOHC_01910 1.44e-175 ywmB - - S - - - TATA-box binding
NPDJDOHC_01911 2.25e-45 ywzB - - S - - - membrane
NPDJDOHC_01912 1.76e-118 ywmA - - - - - - -
NPDJDOHC_01913 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NPDJDOHC_01914 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPDJDOHC_01915 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPDJDOHC_01916 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPDJDOHC_01917 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPDJDOHC_01918 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPDJDOHC_01919 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPDJDOHC_01920 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NPDJDOHC_01921 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NPDJDOHC_01922 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPDJDOHC_01923 3.07e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPDJDOHC_01924 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
NPDJDOHC_01925 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NPDJDOHC_01926 2.08e-101 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPDJDOHC_01927 1.17e-119 mntP - - P - - - Probably functions as a manganese efflux pump
NPDJDOHC_01928 6.77e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPDJDOHC_01929 5.15e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NPDJDOHC_01930 2.05e-156 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NPDJDOHC_01931 7.26e-80 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NPDJDOHC_01933 4.19e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPDJDOHC_01934 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPDJDOHC_01935 9.07e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPDJDOHC_01936 1.04e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NPDJDOHC_01937 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NPDJDOHC_01938 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NPDJDOHC_01939 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NPDJDOHC_01940 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NPDJDOHC_01941 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NPDJDOHC_01942 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NPDJDOHC_01943 3.9e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPDJDOHC_01944 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NPDJDOHC_01945 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NPDJDOHC_01946 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NPDJDOHC_01947 8.11e-121 ywjG - - S - - - Domain of unknown function (DUF2529)
NPDJDOHC_01948 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPDJDOHC_01949 6.53e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPDJDOHC_01950 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NPDJDOHC_01951 2.18e-288 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NPDJDOHC_01952 1.25e-238 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NPDJDOHC_01953 7.93e-59 ywjC - - - - - - -
NPDJDOHC_01954 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NPDJDOHC_01955 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPDJDOHC_01956 1.05e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPDJDOHC_01957 1.45e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NPDJDOHC_01958 8.29e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NPDJDOHC_01959 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NPDJDOHC_01960 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPDJDOHC_01961 2.49e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NPDJDOHC_01962 2.72e-181 ywiC - - S - - - YwiC-like protein
NPDJDOHC_01963 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NPDJDOHC_01964 1.05e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NPDJDOHC_01965 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NPDJDOHC_01966 1.14e-96 ywiB - - S - - - protein conserved in bacteria
NPDJDOHC_01968 5.69e-314 ywhL - - CO - - - amine dehydrogenase activity
NPDJDOHC_01969 1.99e-299 ywhK - - CO - - - amine dehydrogenase activity
NPDJDOHC_01970 1.16e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NPDJDOHC_01972 9.15e-41 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
NPDJDOHC_01973 2.41e-45 - - - - - - - -
NPDJDOHC_01974 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
NPDJDOHC_01976 2.07e-101 - - - CP - - - Membrane
NPDJDOHC_01979 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NPDJDOHC_01980 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NPDJDOHC_01981 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NPDJDOHC_01982 7.67e-109 - - - - - - - -
NPDJDOHC_01983 3.32e-124 ywhD - - S - - - YwhD family
NPDJDOHC_01984 2.31e-154 ywhC - - S - - - Peptidase family M50
NPDJDOHC_01985 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NPDJDOHC_01986 1.02e-93 ywhA - - K - - - Transcriptional regulator
NPDJDOHC_01987 2.71e-316 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
NPDJDOHC_01988 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
NPDJDOHC_01989 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NPDJDOHC_01990 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NPDJDOHC_01991 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NPDJDOHC_01992 4.58e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
NPDJDOHC_01993 3.23e-121 - - - S - - - membrane
NPDJDOHC_01994 8.51e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_01995 1.79e-216 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
NPDJDOHC_01998 1.21e-230 - - - - - - - -
NPDJDOHC_02000 1.58e-204 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NPDJDOHC_02001 3.89e-211 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_02002 1.85e-217 - - - S - - - Conserved hypothetical protein 698
NPDJDOHC_02003 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NPDJDOHC_02004 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NPDJDOHC_02005 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NPDJDOHC_02006 1.33e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NPDJDOHC_02007 1.41e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NPDJDOHC_02008 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NPDJDOHC_02009 8.05e-181 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_02010 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NPDJDOHC_02011 1.4e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NPDJDOHC_02012 4.24e-288 ywfA - - EGP - - - -transporter
NPDJDOHC_02013 2.17e-268 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NPDJDOHC_02014 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NPDJDOHC_02015 0.0 rocB - - E - - - arginine degradation protein
NPDJDOHC_02016 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NPDJDOHC_02017 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NPDJDOHC_02018 3.44e-211 - - - T - - - Histidine kinase
NPDJDOHC_02019 2.59e-162 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_02020 5.52e-61 - - - S - - - Putative adhesin
NPDJDOHC_02021 9.66e-110 - - - - - - - -
NPDJDOHC_02022 1.48e-153 - - - S - - - ABC-2 family transporter protein
NPDJDOHC_02023 2.28e-222 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_02024 8.08e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NPDJDOHC_02025 2.86e-209 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPDJDOHC_02026 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPDJDOHC_02027 6.9e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPDJDOHC_02028 2.97e-244 spsG - - M - - - Spore Coat
NPDJDOHC_02029 2.22e-177 spsF - - M ko:K07257 - ko00000 Spore Coat
NPDJDOHC_02030 3.01e-275 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NPDJDOHC_02031 9.93e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NPDJDOHC_02032 5.29e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NPDJDOHC_02033 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NPDJDOHC_02034 9.06e-184 spsA - - M - - - Spore Coat
NPDJDOHC_02035 1.49e-89 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NPDJDOHC_02036 3.75e-77 ywdK - - S - - - small membrane protein
NPDJDOHC_02037 1.19e-294 ywdJ - - F - - - Xanthine uracil
NPDJDOHC_02038 3.04e-62 ywdI - - S - - - Family of unknown function (DUF5327)
NPDJDOHC_02039 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPDJDOHC_02040 1.52e-197 ywdF - - S - - - Glycosyltransferase like family 2
NPDJDOHC_02042 3.46e-116 ywdD - - - - - - -
NPDJDOHC_02043 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NPDJDOHC_02044 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NPDJDOHC_02045 3.52e-26 ywdA - - - - - - -
NPDJDOHC_02046 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NPDJDOHC_02047 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_02048 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NPDJDOHC_02050 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NPDJDOHC_02051 7.25e-240 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDJDOHC_02052 1.55e-72 - - - L - - - COG2963 Transposase and inactivated derivatives
NPDJDOHC_02053 2.32e-172 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
NPDJDOHC_02054 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NPDJDOHC_02055 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NPDJDOHC_02056 1.2e-106 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NPDJDOHC_02057 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NPDJDOHC_02058 8.22e-85 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NPDJDOHC_02059 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NPDJDOHC_02060 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPDJDOHC_02061 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NPDJDOHC_02062 5.74e-48 ydaS - - S - - - membrane
NPDJDOHC_02063 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NPDJDOHC_02064 6.52e-292 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPDJDOHC_02065 5.1e-83 gtcA - - S - - - GtrA-like protein
NPDJDOHC_02066 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
NPDJDOHC_02068 7.5e-168 - - - H - - - Methionine biosynthesis protein MetW
NPDJDOHC_02069 1.03e-173 - - - S - - - Streptomycin biosynthesis protein StrF
NPDJDOHC_02070 3.09e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NPDJDOHC_02071 9.68e-313 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NPDJDOHC_02072 5.18e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NPDJDOHC_02073 2.35e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NPDJDOHC_02074 4.83e-202 ywbI - - K - - - Transcriptional regulator
NPDJDOHC_02075 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NPDJDOHC_02076 6.47e-144 ywbG - - M - - - effector of murein hydrolase
NPDJDOHC_02077 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NPDJDOHC_02078 1.02e-183 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NPDJDOHC_02079 3.65e-221 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NPDJDOHC_02080 1.53e-286 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NPDJDOHC_02081 1.29e-88 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NPDJDOHC_02082 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPDJDOHC_02083 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NPDJDOHC_02084 4.43e-209 gspA - - M - - - General stress
NPDJDOHC_02085 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NPDJDOHC_02086 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NPDJDOHC_02087 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NPDJDOHC_02088 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_02089 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NPDJDOHC_02090 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_02091 1.31e-290 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPDJDOHC_02092 1.41e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NPDJDOHC_02093 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPDJDOHC_02094 2.9e-68 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_02095 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPDJDOHC_02096 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NPDJDOHC_02097 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NPDJDOHC_02098 4.77e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NPDJDOHC_02099 2e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_02100 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_02101 9.23e-214 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NPDJDOHC_02102 3.3e-79 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NPDJDOHC_02103 2.8e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NPDJDOHC_02104 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_02105 6.75e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_02106 7.31e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPDJDOHC_02107 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NPDJDOHC_02108 3.93e-217 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NPDJDOHC_02109 2.17e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NPDJDOHC_02110 6.75e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NPDJDOHC_02111 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NPDJDOHC_02112 2.75e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NPDJDOHC_02113 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NPDJDOHC_02114 1.85e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPDJDOHC_02115 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NPDJDOHC_02116 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NPDJDOHC_02117 9.56e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NPDJDOHC_02118 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NPDJDOHC_02119 4.75e-289 cimH - - C - - - COG3493 Na citrate symporter
NPDJDOHC_02120 1.2e-200 yxkH - - G - - - Polysaccharide deacetylase
NPDJDOHC_02121 6.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NPDJDOHC_02122 2.66e-217 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NPDJDOHC_02123 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPDJDOHC_02124 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
NPDJDOHC_02125 3.94e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NPDJDOHC_02126 8.44e-303 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NPDJDOHC_02129 7.42e-112 yxjI - - S - - - LURP-one-related
NPDJDOHC_02130 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NPDJDOHC_02131 2.65e-215 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NPDJDOHC_02132 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPDJDOHC_02133 3.75e-126 - - - T - - - Domain of unknown function (DUF4163)
NPDJDOHC_02134 1.61e-68 yxiS - - - - - - -
NPDJDOHC_02135 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NPDJDOHC_02136 2.84e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NPDJDOHC_02137 8.45e-187 bglS - - M - - - licheninase activity
NPDJDOHC_02138 1.19e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NPDJDOHC_02139 2.21e-283 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NPDJDOHC_02140 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NPDJDOHC_02143 4.25e-82 - - - S - - - SMI1-KNR4 cell-wall
NPDJDOHC_02144 4.01e-118 yxiI - - S - - - Protein of unknown function (DUF2716)
NPDJDOHC_02146 5.75e-98 yxiG - - - - - - -
NPDJDOHC_02147 2.34e-93 yxxG - - - - - - -
NPDJDOHC_02149 1.2e-260 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NPDJDOHC_02150 1.78e-209 yxxF - - EG - - - EamA-like transporter family
NPDJDOHC_02151 1.26e-96 yxiE - - T - - - Belongs to the universal stress protein A family
NPDJDOHC_02152 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NPDJDOHC_02153 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_02154 0.0 - - - L - - - HKD family nuclease
NPDJDOHC_02155 1.44e-86 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NPDJDOHC_02156 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NPDJDOHC_02157 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NPDJDOHC_02158 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NPDJDOHC_02159 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NPDJDOHC_02160 1.41e-302 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NPDJDOHC_02161 2.13e-228 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NPDJDOHC_02162 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NPDJDOHC_02163 4.69e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NPDJDOHC_02164 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPDJDOHC_02165 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPDJDOHC_02166 6.05e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NPDJDOHC_02167 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
NPDJDOHC_02170 2.06e-42 yxeE - - - - - - -
NPDJDOHC_02171 5.09e-35 yxeD - - - - - - -
NPDJDOHC_02172 1.34e-20 - - - - - - - -
NPDJDOHC_02174 4.49e-232 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NPDJDOHC_02175 1.55e-72 - - - L - - - COG2963 Transposase and inactivated derivatives
NPDJDOHC_02176 3.3e-172 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
NPDJDOHC_02177 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NPDJDOHC_02178 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NPDJDOHC_02179 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NPDJDOHC_02180 4.77e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NPDJDOHC_02181 7.3e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
NPDJDOHC_02182 1.84e-64 yqfZ - - M ko:K06417 - ko00000 LysM domain
NPDJDOHC_02183 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NPDJDOHC_02184 3.34e-80 yqfX - - S - - - membrane
NPDJDOHC_02185 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NPDJDOHC_02186 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NPDJDOHC_02187 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NPDJDOHC_02188 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
NPDJDOHC_02189 4.23e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NPDJDOHC_02190 1.2e-314 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPDJDOHC_02191 4.16e-89 yqfQ - - S - - - YqfQ-like protein
NPDJDOHC_02192 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NPDJDOHC_02193 7.93e-271 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPDJDOHC_02194 2.97e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NPDJDOHC_02195 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NPDJDOHC_02196 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPDJDOHC_02197 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPDJDOHC_02198 3.33e-113 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NPDJDOHC_02199 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPDJDOHC_02200 5.89e-145 ccpN - - K - - - CBS domain
NPDJDOHC_02201 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NPDJDOHC_02202 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NPDJDOHC_02203 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NPDJDOHC_02204 6e-24 - - - S - - - YqzL-like protein
NPDJDOHC_02205 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPDJDOHC_02206 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NPDJDOHC_02207 6.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NPDJDOHC_02208 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPDJDOHC_02209 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NPDJDOHC_02210 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NPDJDOHC_02211 8.17e-286 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NPDJDOHC_02212 3.57e-61 yqfC - - S - - - sporulation protein YqfC
NPDJDOHC_02213 7.93e-89 yqfB - - - - - - -
NPDJDOHC_02214 4.48e-189 yqfA - - S - - - UPF0365 protein
NPDJDOHC_02215 3.28e-296 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NPDJDOHC_02216 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NPDJDOHC_02217 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NPDJDOHC_02218 8.3e-203 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NPDJDOHC_02219 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NPDJDOHC_02220 1.75e-181 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPDJDOHC_02221 6.58e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NPDJDOHC_02222 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPDJDOHC_02223 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NPDJDOHC_02224 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPDJDOHC_02225 5.74e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPDJDOHC_02226 2.04e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NPDJDOHC_02227 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPDJDOHC_02228 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
NPDJDOHC_02229 9.09e-280 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NPDJDOHC_02230 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NPDJDOHC_02231 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NPDJDOHC_02232 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NPDJDOHC_02233 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NPDJDOHC_02234 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NPDJDOHC_02235 1.51e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NPDJDOHC_02236 1.19e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPDJDOHC_02237 1.02e-179 yqeM - - Q - - - Methyltransferase
NPDJDOHC_02238 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPDJDOHC_02239 1.68e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NPDJDOHC_02240 7.09e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPDJDOHC_02241 3.12e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NPDJDOHC_02242 2.52e-202 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPDJDOHC_02243 1.17e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NPDJDOHC_02244 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NPDJDOHC_02246 1.85e-180 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NPDJDOHC_02247 1.2e-182 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NPDJDOHC_02248 2.92e-138 yqeD - - S - - - SNARE associated Golgi protein
NPDJDOHC_02249 1.68e-18 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NPDJDOHC_02250 4.18e-282 - - - EGP - - - Transmembrane secretion effector
NPDJDOHC_02251 5.58e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPDJDOHC_02252 1.72e-209 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
NPDJDOHC_02253 6.92e-123 - - - K - - - Transcriptional regulator PadR-like family
NPDJDOHC_02254 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
NPDJDOHC_02255 2.67e-308 yrkQ - - T - - - Histidine kinase
NPDJDOHC_02256 2.5e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
NPDJDOHC_02258 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
NPDJDOHC_02259 3.27e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
NPDJDOHC_02260 1.63e-131 yqaC - - F - - - adenylate kinase activity
NPDJDOHC_02261 3.54e-113 - - - K - - - acetyltransferase
NPDJDOHC_02262 1.42e-122 - - - S - - - DinB family
NPDJDOHC_02264 3.71e-193 supH - - S - - - hydrolase
NPDJDOHC_02265 3.29e-193 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NPDJDOHC_02266 1.23e-169 - - - K - - - Helix-turn-helix domain, rpiR family
NPDJDOHC_02267 4.54e-243 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NPDJDOHC_02268 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_02269 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NPDJDOHC_02270 2.06e-234 romA - - S - - - Beta-lactamase superfamily domain
NPDJDOHC_02271 1.96e-108 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPDJDOHC_02272 1.94e-213 yybE - - K - - - Transcriptional regulator
NPDJDOHC_02273 2.38e-273 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_02274 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NPDJDOHC_02275 3.36e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NPDJDOHC_02276 1.33e-122 yrhH - - Q - - - methyltransferase
NPDJDOHC_02277 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NPDJDOHC_02278 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NPDJDOHC_02279 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NPDJDOHC_02280 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NPDJDOHC_02281 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
NPDJDOHC_02282 3.31e-47 yrhC - - S - - - YrhC-like protein
NPDJDOHC_02283 1.17e-271 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NPDJDOHC_02284 7.96e-219 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NPDJDOHC_02285 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPDJDOHC_02286 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NPDJDOHC_02287 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
NPDJDOHC_02288 1.85e-126 yrrS - - S - - - Protein of unknown function (DUF1510)
NPDJDOHC_02289 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NPDJDOHC_02290 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPDJDOHC_02291 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NPDJDOHC_02292 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NPDJDOHC_02293 1.33e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NPDJDOHC_02294 4.01e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NPDJDOHC_02295 2.82e-259 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPDJDOHC_02296 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
NPDJDOHC_02297 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPDJDOHC_02298 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
NPDJDOHC_02299 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPDJDOHC_02300 2.82e-238 yrrI - - S - - - AI-2E family transporter
NPDJDOHC_02301 2.8e-171 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NPDJDOHC_02302 1.56e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NPDJDOHC_02303 2.38e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NPDJDOHC_02304 7.94e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NPDJDOHC_02305 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
NPDJDOHC_02306 8.4e-42 yrzR - - - - - - -
NPDJDOHC_02307 1.76e-107 yrrD - - S - - - protein conserved in bacteria
NPDJDOHC_02308 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPDJDOHC_02309 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
NPDJDOHC_02310 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPDJDOHC_02311 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NPDJDOHC_02312 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_02313 1.85e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NPDJDOHC_02314 1.18e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NPDJDOHC_02315 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPDJDOHC_02316 7.37e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NPDJDOHC_02319 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NPDJDOHC_02320 3.48e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPDJDOHC_02321 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPDJDOHC_02322 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPDJDOHC_02323 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NPDJDOHC_02324 4.68e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NPDJDOHC_02325 2.65e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NPDJDOHC_02326 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NPDJDOHC_02327 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
NPDJDOHC_02328 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPDJDOHC_02329 2.03e-143 yrbG - - S - - - membrane
NPDJDOHC_02330 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
NPDJDOHC_02331 1.78e-51 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NPDJDOHC_02332 2.01e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NPDJDOHC_02333 4.96e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NPDJDOHC_02334 1.39e-28 yrzS - - S - - - Protein of unknown function (DUF2905)
NPDJDOHC_02335 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPDJDOHC_02336 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPDJDOHC_02337 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NPDJDOHC_02339 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPDJDOHC_02340 2.6e-263 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NPDJDOHC_02341 1.04e-272 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NPDJDOHC_02342 9.86e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NPDJDOHC_02343 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NPDJDOHC_02344 5.11e-288 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NPDJDOHC_02345 3.02e-124 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NPDJDOHC_02346 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NPDJDOHC_02347 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NPDJDOHC_02348 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPDJDOHC_02349 3.64e-140 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NPDJDOHC_02350 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NPDJDOHC_02351 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NPDJDOHC_02352 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NPDJDOHC_02353 3.59e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NPDJDOHC_02354 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NPDJDOHC_02355 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NPDJDOHC_02356 1.68e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NPDJDOHC_02357 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NPDJDOHC_02358 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NPDJDOHC_02359 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NPDJDOHC_02360 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NPDJDOHC_02361 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NPDJDOHC_02362 2.67e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NPDJDOHC_02363 1.27e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NPDJDOHC_02364 2.04e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NPDJDOHC_02365 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPDJDOHC_02366 1.53e-35 - - - - - - - -
NPDJDOHC_02367 1.89e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NPDJDOHC_02368 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NPDJDOHC_02369 1.62e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NPDJDOHC_02370 1.2e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NPDJDOHC_02371 9.78e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NPDJDOHC_02372 4.44e-224 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NPDJDOHC_02373 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NPDJDOHC_02374 9.08e-317 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NPDJDOHC_02375 8.26e-116 ysxD - - - - - - -
NPDJDOHC_02376 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NPDJDOHC_02377 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NPDJDOHC_02378 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NPDJDOHC_02379 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPDJDOHC_02380 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPDJDOHC_02381 2.34e-241 ysoA - - H - - - Tetratricopeptide repeat
NPDJDOHC_02382 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPDJDOHC_02383 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPDJDOHC_02384 3.68e-256 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NPDJDOHC_02385 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NPDJDOHC_02386 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NPDJDOHC_02387 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NPDJDOHC_02388 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NPDJDOHC_02393 1.21e-120 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NPDJDOHC_02394 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPDJDOHC_02395 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NPDJDOHC_02396 7.73e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NPDJDOHC_02397 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NPDJDOHC_02398 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NPDJDOHC_02399 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_02400 2.67e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NPDJDOHC_02401 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NPDJDOHC_02402 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NPDJDOHC_02403 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NPDJDOHC_02404 6.01e-104 yslB - - S - - - Protein of unknown function (DUF2507)
NPDJDOHC_02405 1.49e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NPDJDOHC_02406 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPDJDOHC_02407 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NPDJDOHC_02408 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NPDJDOHC_02409 5.22e-229 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
NPDJDOHC_02410 8.64e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NPDJDOHC_02411 7.4e-180 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NPDJDOHC_02412 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_02413 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPDJDOHC_02414 1.77e-165 ywbB - - S - - - Protein of unknown function (DUF2711)
NPDJDOHC_02415 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
NPDJDOHC_02416 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPDJDOHC_02417 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NPDJDOHC_02418 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
NPDJDOHC_02419 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NPDJDOHC_02420 7.57e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPDJDOHC_02421 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPDJDOHC_02422 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPDJDOHC_02423 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPDJDOHC_02424 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NPDJDOHC_02425 4.53e-264 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NPDJDOHC_02426 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
NPDJDOHC_02427 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NPDJDOHC_02428 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NPDJDOHC_02429 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NPDJDOHC_02430 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NPDJDOHC_02431 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
NPDJDOHC_02432 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NPDJDOHC_02433 2.09e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NPDJDOHC_02434 1.85e-182 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NPDJDOHC_02435 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NPDJDOHC_02436 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NPDJDOHC_02437 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NPDJDOHC_02438 1.71e-241 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NPDJDOHC_02439 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
NPDJDOHC_02440 9.71e-90 ysdB - - S - - - Sigma-w pathway protein YsdB
NPDJDOHC_02441 8.03e-58 ysdA - - S - - - Membrane
NPDJDOHC_02442 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPDJDOHC_02443 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NPDJDOHC_02444 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPDJDOHC_02445 1.08e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NPDJDOHC_02446 2.76e-69 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
NPDJDOHC_02447 1.05e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NPDJDOHC_02448 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_02449 2.52e-194 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NPDJDOHC_02450 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPDJDOHC_02451 5.94e-199 ytxC - - S - - - YtxC-like family
NPDJDOHC_02452 4.64e-142 ytxB - - S - - - SNARE associated Golgi protein
NPDJDOHC_02453 1.42e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NPDJDOHC_02454 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NPDJDOHC_02455 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPDJDOHC_02456 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NPDJDOHC_02457 1.09e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPDJDOHC_02458 1.69e-89 ytcD - - K - - - Transcriptional regulator
NPDJDOHC_02459 4.15e-261 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NPDJDOHC_02460 1.93e-206 ytbE - - S - - - reductase
NPDJDOHC_02461 1.52e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPDJDOHC_02462 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
NPDJDOHC_02463 9.87e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPDJDOHC_02464 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPDJDOHC_02465 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NPDJDOHC_02466 2.9e-167 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_02467 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NPDJDOHC_02468 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NPDJDOHC_02469 1.42e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NPDJDOHC_02470 2.33e-84 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NPDJDOHC_02471 5.65e-96 ytwI - - S - - - membrane
NPDJDOHC_02472 9.96e-248 ytvI - - S - - - sporulation integral membrane protein YtvI
NPDJDOHC_02473 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NPDJDOHC_02474 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NPDJDOHC_02475 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPDJDOHC_02476 1.15e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NPDJDOHC_02477 1.53e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPDJDOHC_02478 1.48e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NPDJDOHC_02479 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NPDJDOHC_02480 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
NPDJDOHC_02481 2.64e-114 ytrI - - - - - - -
NPDJDOHC_02482 7.04e-32 - - - - - - - -
NPDJDOHC_02483 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NPDJDOHC_02484 1.06e-63 ytpI - - S - - - YtpI-like protein
NPDJDOHC_02485 6.77e-305 ytoI - - K - - - transcriptional regulator containing CBS domains
NPDJDOHC_02486 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
NPDJDOHC_02487 2.06e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_02489 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NPDJDOHC_02490 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPDJDOHC_02491 4.03e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NPDJDOHC_02492 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPDJDOHC_02493 7.8e-237 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NPDJDOHC_02494 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPDJDOHC_02495 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
NPDJDOHC_02496 3.82e-158 ytfI - - S - - - Protein of unknown function (DUF2953)
NPDJDOHC_02497 2.77e-114 yteJ - - S - - - RDD family
NPDJDOHC_02498 2.23e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NPDJDOHC_02499 8.09e-197 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPDJDOHC_02500 0.0 ytcJ - - S - - - amidohydrolase
NPDJDOHC_02501 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NPDJDOHC_02502 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NPDJDOHC_02503 1.47e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPDJDOHC_02504 1.42e-268 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NPDJDOHC_02505 1.68e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NPDJDOHC_02506 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPDJDOHC_02507 1.85e-199 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NPDJDOHC_02508 3.57e-143 yttP - - K - - - Transcriptional regulator
NPDJDOHC_02509 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NPDJDOHC_02510 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
NPDJDOHC_02511 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPDJDOHC_02512 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NPDJDOHC_02513 1.96e-136 yokH - - G - - - SMI1 / KNR4 family
NPDJDOHC_02515 6.45e-132 - - - - - - - -
NPDJDOHC_02517 7.51e-116 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NPDJDOHC_02519 1.99e-39 - - - S - - - Phage-like element PBSX protein XtrA
NPDJDOHC_02520 2.93e-41 - - - - - - - -
NPDJDOHC_02521 1.4e-44 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NPDJDOHC_02522 9.55e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NPDJDOHC_02524 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NPDJDOHC_02526 1.29e-180 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NPDJDOHC_02527 6.08e-194 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPDJDOHC_02528 7.76e-191 - - - K - - - Transcriptional regulator
NPDJDOHC_02529 9.98e-161 ygaZ - - E - - - AzlC protein
NPDJDOHC_02530 3.06e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NPDJDOHC_02531 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPDJDOHC_02532 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NPDJDOHC_02533 2.96e-157 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NPDJDOHC_02534 5.07e-151 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NPDJDOHC_02535 3.49e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NPDJDOHC_02536 3.66e-156 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NPDJDOHC_02537 1.82e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NPDJDOHC_02538 2.06e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NPDJDOHC_02539 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NPDJDOHC_02540 5.9e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
NPDJDOHC_02541 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NPDJDOHC_02542 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPDJDOHC_02543 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NPDJDOHC_02544 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NPDJDOHC_02545 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPDJDOHC_02546 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
NPDJDOHC_02547 5.47e-76 ytpP - - CO - - - Thioredoxin
NPDJDOHC_02548 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NPDJDOHC_02549 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NPDJDOHC_02550 9.96e-69 ytzB - - S - - - small secreted protein
NPDJDOHC_02551 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NPDJDOHC_02552 6.76e-212 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NPDJDOHC_02553 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPDJDOHC_02554 6.69e-61 ytzH - - S - - - YtzH-like protein
NPDJDOHC_02555 2.93e-199 ytmP - - M - - - Phosphotransferase
NPDJDOHC_02556 6.37e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NPDJDOHC_02557 5.36e-219 ytlQ - - - - - - -
NPDJDOHC_02558 3.82e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NPDJDOHC_02559 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NPDJDOHC_02560 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NPDJDOHC_02561 1.48e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NPDJDOHC_02562 9.45e-281 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NPDJDOHC_02563 2.31e-166 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NPDJDOHC_02564 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NPDJDOHC_02565 8.68e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NPDJDOHC_02566 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPDJDOHC_02567 9.17e-300 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NPDJDOHC_02568 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NPDJDOHC_02569 2.14e-36 yteV - - S - - - Sporulation protein Cse60
NPDJDOHC_02570 1.35e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_02571 1.44e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NPDJDOHC_02572 6.79e-219 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NPDJDOHC_02573 1.01e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NPDJDOHC_02574 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NPDJDOHC_02575 2.06e-112 - - - M - - - Acetyltransferase (GNAT) domain
NPDJDOHC_02576 6.05e-69 ytwF - - P - - - Sulfurtransferase
NPDJDOHC_02577 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NPDJDOHC_02578 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
NPDJDOHC_02579 8.76e-177 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NPDJDOHC_02580 2.46e-271 yttB - - EGP - - - Major facilitator superfamily
NPDJDOHC_02581 2.13e-169 ywaF - - S - - - Integral membrane protein
NPDJDOHC_02582 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NPDJDOHC_02583 2.3e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_02584 2.23e-224 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NPDJDOHC_02585 1.57e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_02586 4.75e-288 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NPDJDOHC_02587 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_02588 1.7e-214 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NPDJDOHC_02589 3.18e-236 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NPDJDOHC_02590 2.06e-232 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NPDJDOHC_02591 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_02592 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NPDJDOHC_02594 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
NPDJDOHC_02595 0.0 - - - IQ - - - AMP-binding enzyme
NPDJDOHC_02596 5.31e-265 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NPDJDOHC_02597 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_02598 0.0 - - - Q ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_02599 3.89e-241 - - - C - - - Nitroreductase
NPDJDOHC_02600 7.18e-170 aveG - - Q - - - Thioesterase domain
NPDJDOHC_02601 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_02602 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NPDJDOHC_02603 1.08e-137 ytqB - - J - - - Putative rRNA methylase
NPDJDOHC_02605 1.1e-186 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
NPDJDOHC_02606 2.45e-272 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NPDJDOHC_02607 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NPDJDOHC_02608 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NPDJDOHC_02609 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NPDJDOHC_02610 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NPDJDOHC_02611 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPDJDOHC_02612 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NPDJDOHC_02613 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
NPDJDOHC_02614 4.02e-192 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NPDJDOHC_02615 3.88e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NPDJDOHC_02616 2.6e-185 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NPDJDOHC_02617 2.19e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NPDJDOHC_02618 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NPDJDOHC_02619 2.12e-80 ytkC - - S - - - Bacteriophage holin family
NPDJDOHC_02620 3.12e-100 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NPDJDOHC_02622 4.4e-101 ytkA - - S - - - YtkA-like
NPDJDOHC_02623 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPDJDOHC_02624 8.41e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NPDJDOHC_02625 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NPDJDOHC_02626 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NPDJDOHC_02627 2.22e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NPDJDOHC_02628 3.85e-237 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NPDJDOHC_02629 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NPDJDOHC_02630 1.74e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NPDJDOHC_02631 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NPDJDOHC_02632 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NPDJDOHC_02633 7.53e-201 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NPDJDOHC_02634 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NPDJDOHC_02635 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NPDJDOHC_02636 1.28e-170 yteA - - T - - - COG1734 DnaK suppressor protein
NPDJDOHC_02637 7.73e-104 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NPDJDOHC_02661 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPDJDOHC_02662 2.83e-237 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NPDJDOHC_02663 5.06e-113 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NPDJDOHC_02664 4.41e-214 ydhU - - P ko:K07217 - ko00000 Catalase
NPDJDOHC_02665 0.0 ybeC - - E - - - amino acid
NPDJDOHC_02666 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
NPDJDOHC_02667 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NPDJDOHC_02668 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NPDJDOHC_02669 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NPDJDOHC_02670 3.96e-155 - - - K ko:K05799 - ko00000,ko03000 FCD
NPDJDOHC_02671 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NPDJDOHC_02672 1.11e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NPDJDOHC_02673 4.3e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
NPDJDOHC_02675 0.0 pbpE - - V - - - Beta-lactamase
NPDJDOHC_02678 4.77e-291 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NPDJDOHC_02679 2.79e-155 ydhC - - K - - - FCD
NPDJDOHC_02680 2e-26 - 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NPDJDOHC_02681 4.32e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NPDJDOHC_02682 6.92e-190 - - - Q - - - ubiE/COQ5 methyltransferase family
NPDJDOHC_02683 2.44e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NPDJDOHC_02684 1.61e-194 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPDJDOHC_02685 1.29e-196 bltR - - K - - - helix_turn_helix, mercury resistance
NPDJDOHC_02686 2.62e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NPDJDOHC_02687 9e-158 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NPDJDOHC_02688 2.73e-201 - - - K - - - Helix-turn-helix XRE-family like proteins
NPDJDOHC_02689 8.62e-292 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPDJDOHC_02690 8.22e-270 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NPDJDOHC_02691 7.09e-251 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NPDJDOHC_02692 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NPDJDOHC_02693 5.71e-131 ynaD - - J - - - Acetyltransferase (GNAT) domain
NPDJDOHC_02694 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NPDJDOHC_02695 1.04e-174 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
NPDJDOHC_02696 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NPDJDOHC_02697 1.19e-143 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPDJDOHC_02698 1.96e-281 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_02699 2.95e-50 yraG - - - ko:K06440 - ko00000 -
NPDJDOHC_02700 2.86e-85 yraF - - M - - - Spore coat protein
NPDJDOHC_02701 1.29e-283 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPDJDOHC_02702 3.54e-35 yraE - - - ko:K06440 - ko00000 -
NPDJDOHC_02703 1.25e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
NPDJDOHC_02704 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPDJDOHC_02705 3.17e-203 ydeK - - EG - - - -transporter
NPDJDOHC_02706 1.2e-132 ydeS - - K - - - Transcriptional regulator
NPDJDOHC_02707 1.36e-253 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
NPDJDOHC_02708 7.73e-139 - - - S - - - SNARE associated Golgi protein
NPDJDOHC_02709 9.62e-248 - - - T - - - COG0642 Signal transduction histidine kinase
NPDJDOHC_02710 1.06e-159 - - - T - - - Transcriptional regulator
NPDJDOHC_02711 3.6e-145 - - - I - - - Ribosomal RNA adenine dimethylase
NPDJDOHC_02713 4.37e-148 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
NPDJDOHC_02714 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NPDJDOHC_02715 3.51e-291 nhaC_1 - - C - - - antiporter
NPDJDOHC_02716 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NPDJDOHC_02717 6.64e-260 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NPDJDOHC_02718 8.2e-219 - - - S - - - Sodium Bile acid symporter family
NPDJDOHC_02719 1.69e-298 - - - G - - - Haloacid dehalogenase-like hydrolase
NPDJDOHC_02720 5.46e-193 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NPDJDOHC_02721 9.13e-191 - - - Q - - - ubiE/COQ5 methyltransferase family
NPDJDOHC_02722 3.94e-250 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPDJDOHC_02723 4.51e-111 - - - F - - - nucleoside 2-deoxyribosyltransferase
NPDJDOHC_02724 2.23e-75 ydeH - - - - - - -
NPDJDOHC_02725 6.11e-256 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NPDJDOHC_02727 6.3e-192 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
NPDJDOHC_02728 2.2e-116 ykkA - - S - - - Protein of unknown function (DUF664)
NPDJDOHC_02730 4.01e-132 yrkC - - G - - - Cupin domain
NPDJDOHC_02732 2.69e-257 trkA - - P ko:K07222 - ko00000 Oxidoreductase
NPDJDOHC_02733 1.17e-219 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NPDJDOHC_02734 5.28e-104 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPDJDOHC_02735 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
NPDJDOHC_02738 1.48e-86 - - - G - - - Cupin domain
NPDJDOHC_02739 4.3e-111 - - - S - - - DinB superfamily
NPDJDOHC_02740 1.84e-236 - - - S - - - Patatin-like phospholipase
NPDJDOHC_02741 4.93e-303 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_02742 1.18e-222 ybfA - - K - - - FR47-like protein
NPDJDOHC_02743 9.96e-69 - - - K - - - Transcriptional regulator PadR-like family
NPDJDOHC_02744 1.18e-139 - - - S - - - Protein of unknown function (DUF2812)
NPDJDOHC_02745 9.82e-164 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NPDJDOHC_02746 2.16e-167 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
NPDJDOHC_02747 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
NPDJDOHC_02748 4.1e-254 yrkH - - P - - - Rhodanese Homology Domain
NPDJDOHC_02749 3.94e-133 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
NPDJDOHC_02750 1.17e-84 - - - P - - - Rhodanese Homology Domain
NPDJDOHC_02751 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
NPDJDOHC_02752 2.63e-53 yrkD - - S - - - protein conserved in bacteria
NPDJDOHC_02753 2.51e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
NPDJDOHC_02754 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NPDJDOHC_02755 1.13e-252 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NPDJDOHC_02756 6.06e-75 - - - K - - - Transcriptional regulator
NPDJDOHC_02757 1.62e-227 - - - C - - - COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NPDJDOHC_02758 2.13e-233 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NPDJDOHC_02759 2.48e-173 - - - C ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
NPDJDOHC_02760 7.04e-133 - - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
NPDJDOHC_02761 1.4e-147 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NPDJDOHC_02762 3.48e-98 ywnA - - K - - - Transcriptional regulator
NPDJDOHC_02763 1.59e-85 - - - S - - - YjbR
NPDJDOHC_02764 4.48e-98 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
NPDJDOHC_02765 8.64e-112 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
NPDJDOHC_02766 5.16e-66 ohrR - - K - - - Transcriptional regulator
NPDJDOHC_02767 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
NPDJDOHC_02768 2.73e-201 - - - S - - - Serine aminopeptidase, S33
NPDJDOHC_02769 1.16e-93 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
NPDJDOHC_02770 5.42e-182 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
NPDJDOHC_02771 4.71e-98 - - - S - - - SnoaL-like polyketide cyclase
NPDJDOHC_02772 3.44e-127 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
NPDJDOHC_02780 1.81e-77 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NPDJDOHC_02781 1.78e-21 - - - - - - - -
NPDJDOHC_02782 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NPDJDOHC_02783 4.22e-143 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NPDJDOHC_02784 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPDJDOHC_02785 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NPDJDOHC_02786 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NPDJDOHC_02787 2.17e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NPDJDOHC_02788 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NPDJDOHC_02789 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NPDJDOHC_02790 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NPDJDOHC_02791 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NPDJDOHC_02792 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NPDJDOHC_02793 7.21e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPDJDOHC_02794 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NPDJDOHC_02795 5.81e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPDJDOHC_02796 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NPDJDOHC_02797 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NPDJDOHC_02798 6.83e-109 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NPDJDOHC_02799 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPDJDOHC_02800 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPDJDOHC_02801 5.31e-259 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NPDJDOHC_02802 2.25e-74 ydbP - - CO - - - Thioredoxin
NPDJDOHC_02803 8.5e-116 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPDJDOHC_02804 2.8e-79 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPDJDOHC_02805 6.58e-14 - - - S - - - Fur-regulated basic protein A
NPDJDOHC_02806 1.13e-15 - - - S - - - Fur-regulated basic protein B
NPDJDOHC_02807 3.47e-267 ydbM - - I - - - acyl-CoA dehydrogenase
NPDJDOHC_02808 2.29e-70 ydbL - - - - - - -
NPDJDOHC_02809 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPDJDOHC_02810 1.67e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_02811 8.61e-231 ydbI - - S - - - AI-2E family transporter
NPDJDOHC_02812 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPDJDOHC_02813 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NPDJDOHC_02814 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NPDJDOHC_02815 4.65e-256 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NPDJDOHC_02816 1.64e-199 ydbD - - P ko:K07217 - ko00000 Catalase
NPDJDOHC_02817 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
NPDJDOHC_02818 7.98e-86 ydbB - - G - - - Cupin domain
NPDJDOHC_02819 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
NPDJDOHC_02820 2.29e-183 ydbA - - P - - - EcsC protein family
NPDJDOHC_02821 7.05e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NPDJDOHC_02822 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
NPDJDOHC_02823 1.95e-45 ydaT - - - - - - -
NPDJDOHC_02825 1.6e-289 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NPDJDOHC_02826 1.29e-54 - - - - - - - -
NPDJDOHC_02827 1.79e-131 - - - - - - - -
NPDJDOHC_02828 7.56e-116 - - - - - - - -
NPDJDOHC_02830 5.42e-12 - - - - - - - -
NPDJDOHC_02832 5.37e-271 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NPDJDOHC_02833 6.3e-60 - - - - - - - -
NPDJDOHC_02835 1.45e-98 - - - K - - - acetyltransferase
NPDJDOHC_02836 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NPDJDOHC_02837 3.34e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NPDJDOHC_02838 0.0 ydaO - - E - - - amino acid
NPDJDOHC_02839 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
NPDJDOHC_02840 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
NPDJDOHC_02841 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
NPDJDOHC_02842 7.99e-191 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
NPDJDOHC_02843 4.53e-264 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NPDJDOHC_02844 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPDJDOHC_02845 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NPDJDOHC_02846 5.59e-64 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NPDJDOHC_02847 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NPDJDOHC_02848 1.83e-101 ydaG - - S - - - general stress protein
NPDJDOHC_02849 1.07e-153 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPDJDOHC_02850 1.17e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NPDJDOHC_02851 9.37e-208 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_02852 0.0 ydaB - - IQ - - - acyl-CoA ligase
NPDJDOHC_02853 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NPDJDOHC_02854 7.67e-223 ycsN - - S - - - Oxidoreductase
NPDJDOHC_02855 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NPDJDOHC_02856 5.95e-75 yczJ - - S - - - biosynthesis
NPDJDOHC_02858 5.71e-152 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NPDJDOHC_02859 2.93e-170 kipR - - K - - - Transcriptional regulator
NPDJDOHC_02860 7.58e-244 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NPDJDOHC_02861 4.86e-177 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NPDJDOHC_02862 2.15e-195 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NPDJDOHC_02863 3.24e-272 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NPDJDOHC_02864 6.12e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NPDJDOHC_02865 4.66e-178 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NPDJDOHC_02867 1.74e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NPDJDOHC_02868 4.59e-270 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NPDJDOHC_02869 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NPDJDOHC_02870 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NPDJDOHC_02871 9.6e-73 - - - - - - - -
NPDJDOHC_02872 1.49e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NPDJDOHC_02873 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NPDJDOHC_02874 2.05e-131 ycnI - - S - - - protein conserved in bacteria
NPDJDOHC_02875 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_02876 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NPDJDOHC_02877 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPDJDOHC_02878 2.65e-288 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPDJDOHC_02879 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPDJDOHC_02880 1.37e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NPDJDOHC_02881 3.39e-60 ycnE - - S - - - Monooxygenase
NPDJDOHC_02882 4.14e-176 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
NPDJDOHC_02883 3.14e-197 ycnC - - K - - - Transcriptional regulator
NPDJDOHC_02884 0.0 ycnB - - EGP - - - the major facilitator superfamily
NPDJDOHC_02885 1.18e-224 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NPDJDOHC_02886 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_02887 3.45e-213 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_02888 1.91e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_02889 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NPDJDOHC_02892 1.09e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NPDJDOHC_02893 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
NPDJDOHC_02894 9.08e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_02895 0.0 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NPDJDOHC_02896 4.84e-160 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NPDJDOHC_02897 0.0 yxeQ - - S - - - MmgE/PrpD family
NPDJDOHC_02898 6.14e-280 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NPDJDOHC_02899 1.38e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_02900 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NPDJDOHC_02901 1.56e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NPDJDOHC_02902 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPDJDOHC_02903 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDJDOHC_02904 7.92e-250 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NPDJDOHC_02905 1.3e-305 gerKC - - S ko:K06297 - ko00000 spore germination
NPDJDOHC_02906 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NPDJDOHC_02908 0.0 yclG - - M - - - Pectate lyase superfamily protein
NPDJDOHC_02909 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NPDJDOHC_02910 3.51e-102 yclD - - - - - - -
NPDJDOHC_02911 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
NPDJDOHC_02912 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NPDJDOHC_02913 1.46e-131 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NPDJDOHC_02914 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NPDJDOHC_02915 2.8e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NPDJDOHC_02916 3.03e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NPDJDOHC_02917 8.3e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NPDJDOHC_02918 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
NPDJDOHC_02919 1.11e-168 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NPDJDOHC_02920 0.0 ycxD - - K - - - GntR family transcriptional regulator
NPDJDOHC_02921 8.2e-219 ycxC - - EG - - - EamA-like transporter family
NPDJDOHC_02923 2.38e-86 - - - S - - - YcxB-like protein
NPDJDOHC_02924 0.0 - - - E - - - Aminotransferase class I and II
NPDJDOHC_02925 3.05e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NPDJDOHC_02926 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NPDJDOHC_02927 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_02928 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_02929 1.01e-84 hxlR - - K - - - transcriptional
NPDJDOHC_02930 3.82e-140 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NPDJDOHC_02931 2.67e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NPDJDOHC_02932 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
NPDJDOHC_02933 5.81e-92 nin - - S - - - Competence protein J (ComJ)
NPDJDOHC_02934 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NPDJDOHC_02935 3.31e-68 - - - S - - - Protein of unknown function (DUF2680)
NPDJDOHC_02936 9.31e-97 yckC - - S - - - membrane
NPDJDOHC_02937 7.79e-285 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPDJDOHC_02938 4.25e-291 yciC - - S - - - GTPases (G3E family)
NPDJDOHC_02939 2.09e-287 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NPDJDOHC_02940 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
NPDJDOHC_02941 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPDJDOHC_02942 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NPDJDOHC_02943 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NPDJDOHC_02944 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NPDJDOHC_02945 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NPDJDOHC_02946 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NPDJDOHC_02947 3.14e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPDJDOHC_02948 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NPDJDOHC_02949 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NPDJDOHC_02950 2.23e-191 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NPDJDOHC_02951 2.41e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NPDJDOHC_02952 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NPDJDOHC_02953 1.66e-304 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_02954 7.21e-193 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
NPDJDOHC_02955 4.05e-142 tmrB - - S - - - AAA domain
NPDJDOHC_02956 2.77e-06 - - - S - - - Bacillus cereus group antimicrobial protein
NPDJDOHC_02957 5.46e-193 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPDJDOHC_02958 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NPDJDOHC_02959 5.64e-315 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NPDJDOHC_02960 4.54e-196 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NPDJDOHC_02961 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
NPDJDOHC_02962 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NPDJDOHC_02963 0.0 mdr - - EGP - - - the major facilitator superfamily
NPDJDOHC_02964 1.39e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NPDJDOHC_02965 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
NPDJDOHC_02966 1.32e-107 ycgB - - - - - - -
NPDJDOHC_02967 8.03e-294 ycgA - - S - - - Membrane
NPDJDOHC_02968 5.82e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NPDJDOHC_02969 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NPDJDOHC_02970 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NPDJDOHC_02971 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NPDJDOHC_02972 1.1e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NPDJDOHC_02973 1.17e-246 yceH - - P - - - Belongs to the TelA family
NPDJDOHC_02974 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NPDJDOHC_02975 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NPDJDOHC_02976 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NPDJDOHC_02977 3.63e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NPDJDOHC_02978 2.86e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NPDJDOHC_02979 1.2e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDJDOHC_02980 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NPDJDOHC_02981 6.92e-171 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NPDJDOHC_02982 4.44e-215 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NPDJDOHC_02983 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NPDJDOHC_02984 9.39e-183 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NPDJDOHC_02985 2.45e-249 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NPDJDOHC_02986 6.25e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NPDJDOHC_02987 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NPDJDOHC_02988 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NPDJDOHC_02989 3.39e-228 ycdA - - S - - - Domain of unknown function (DUF5105)
NPDJDOHC_02990 4.79e-222 yccK - - C - - - Aldo keto reductase
NPDJDOHC_02991 2.04e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
NPDJDOHC_02992 9.81e-149 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NPDJDOHC_02993 1.24e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NPDJDOHC_02994 1.54e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NPDJDOHC_02995 2.61e-315 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NPDJDOHC_02996 7.62e-270 ycbU - - E - - - Selenocysteine lyase
NPDJDOHC_02997 1.25e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPDJDOHC_02998 8.93e-163 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPDJDOHC_02999 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NPDJDOHC_03000 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NPDJDOHC_03001 1.33e-104 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NPDJDOHC_03002 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
NPDJDOHC_03003 3.92e-76 ydfQ - - CO - - - Thioredoxin
NPDJDOHC_03004 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
NPDJDOHC_03005 7.8e-238 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NPDJDOHC_03006 8.46e-146 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NPDJDOHC_03007 4.47e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPDJDOHC_03008 5.89e-36 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NPDJDOHC_03009 1e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NPDJDOHC_03010 1.6e-281 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_03011 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NPDJDOHC_03012 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NPDJDOHC_03013 6.39e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NPDJDOHC_03014 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NPDJDOHC_03015 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NPDJDOHC_03016 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPDJDOHC_03017 3.47e-246 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NPDJDOHC_03018 1.09e-57 ybfN - - - - - - -
NPDJDOHC_03019 7.49e-195 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NPDJDOHC_03020 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
NPDJDOHC_03021 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPDJDOHC_03022 9.69e-273 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPDJDOHC_03023 4.68e-259 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NPDJDOHC_03024 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
NPDJDOHC_03025 2.44e-45 - - - - - - - -
NPDJDOHC_03026 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
NPDJDOHC_03028 2.02e-267 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
NPDJDOHC_03029 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
NPDJDOHC_03030 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NPDJDOHC_03031 1.04e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NPDJDOHC_03032 5.14e-22 - - - S - - - Protein of unknown function (DUF2651)
NPDJDOHC_03035 0.0 ybeC - - E - - - amino acid
NPDJDOHC_03036 7.84e-55 ybyB - - - - - - -
NPDJDOHC_03037 1.42e-150 yqeB - - - - - - -
NPDJDOHC_03038 1.75e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NPDJDOHC_03039 2.68e-105 - - - S - - - Domain of unknown function (DUF4879)
NPDJDOHC_03040 2.34e-35 - - - - - - - -
NPDJDOHC_03041 7.79e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NPDJDOHC_03042 1.8e-269 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NPDJDOHC_03043 3.5e-220 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NPDJDOHC_03044 5.23e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NPDJDOHC_03045 1.99e-261 - - - T - - - COG4585 Signal transduction histidine kinase
NPDJDOHC_03046 7.56e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NPDJDOHC_03047 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NPDJDOHC_03048 3.52e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NPDJDOHC_03049 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NPDJDOHC_03050 7.37e-136 yxaC - - M - - - effector of murein hydrolase
NPDJDOHC_03051 3.09e-208 dkgB - - S - - - Aldo/keto reductase family
NPDJDOHC_03053 4.5e-15 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NPDJDOHC_03054 0.0 - - - V ko:K02004,ko:K11632 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NPDJDOHC_03055 3.96e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_03056 3.07e-240 - - - T ko:K19168 - ko00000,ko02048 Histidine kinase
NPDJDOHC_03057 2.14e-163 - - - T ko:K11630 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_03059 7.92e-35 ybdN - - - - - - -
NPDJDOHC_03060 1.27e-141 - - - S - - - ABC-2 family transporter protein
NPDJDOHC_03061 1.64e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NPDJDOHC_03062 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPDJDOHC_03063 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPDJDOHC_03064 1.64e-303 ybbR - - S - - - protein conserved in bacteria
NPDJDOHC_03065 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPDJDOHC_03066 1.11e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NPDJDOHC_03067 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NPDJDOHC_03073 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
NPDJDOHC_03074 3.15e-113 ybbJ - - J - - - acetyltransferase
NPDJDOHC_03075 1.2e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NPDJDOHC_03076 1.83e-313 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_03077 1.95e-316 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NPDJDOHC_03078 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NPDJDOHC_03079 3.46e-304 ybbC - - S - - - protein conserved in bacteria
NPDJDOHC_03080 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NPDJDOHC_03081 2.1e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NPDJDOHC_03082 2.19e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_03083 7.1e-230 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDJDOHC_03084 4.6e-151 ybbA - - S ko:K07017 - ko00000 Putative esterase
NPDJDOHC_03085 1.87e-223 ybaS - - S - - - Na -dependent transporter
NPDJDOHC_03086 1e-290 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NPDJDOHC_03087 1.69e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NPDJDOHC_03088 8.07e-233 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
NPDJDOHC_03089 1.27e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPDJDOHC_03090 5.49e-282 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NPDJDOHC_03093 2.25e-239 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NPDJDOHC_03094 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NPDJDOHC_03095 1.02e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NPDJDOHC_03096 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NPDJDOHC_03097 3.92e-246 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPDJDOHC_03098 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NPDJDOHC_03099 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NPDJDOHC_03100 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPDJDOHC_03101 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NPDJDOHC_03102 8.18e-163 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPDJDOHC_03103 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NPDJDOHC_03104 4.09e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NPDJDOHC_03105 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPDJDOHC_03106 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPDJDOHC_03107 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
NPDJDOHC_03110 8.34e-86 - - - - - - - -
NPDJDOHC_03111 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NPDJDOHC_03112 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NPDJDOHC_03113 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NPDJDOHC_03114 2.29e-225 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NPDJDOHC_03115 5.98e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
NPDJDOHC_03116 7.04e-149 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NPDJDOHC_03117 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPDJDOHC_03118 8.16e-165 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NPDJDOHC_03119 1.94e-224 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NPDJDOHC_03120 0.0 oatA - - I - - - Acyltransferase family
NPDJDOHC_03121 1.68e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
NPDJDOHC_03122 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NPDJDOHC_03123 1.74e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NPDJDOHC_03124 3.92e-83 ydjM - - M - - - Lytic transglycolase
NPDJDOHC_03125 2.12e-196 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NPDJDOHC_03127 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
NPDJDOHC_03128 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NPDJDOHC_03129 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NPDJDOHC_03130 3.04e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPDJDOHC_03131 2.39e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NPDJDOHC_03132 6.89e-278 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NPDJDOHC_03133 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NPDJDOHC_03134 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NPDJDOHC_03135 2.81e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NPDJDOHC_03136 0.0 - - - S - - - Domain of unknown function (DUF4179)
NPDJDOHC_03137 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NPDJDOHC_03138 1.42e-173 yebC - - M - - - Membrane
NPDJDOHC_03140 2.66e-120 yebE - - S - - - UPF0316 protein
NPDJDOHC_03141 6.56e-40 yebG - - S - - - NETI protein
NPDJDOHC_03142 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPDJDOHC_03143 3.9e-288 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPDJDOHC_03144 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPDJDOHC_03145 2.13e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NPDJDOHC_03146 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPDJDOHC_03147 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPDJDOHC_03148 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPDJDOHC_03149 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPDJDOHC_03150 4.57e-245 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NPDJDOHC_03151 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPDJDOHC_03152 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NPDJDOHC_03153 1.85e-303 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NPDJDOHC_03154 4.18e-34 - - - S - - - Protein of unknown function (DUF2892)
NPDJDOHC_03155 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NPDJDOHC_03156 7.32e-248 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NPDJDOHC_03157 2.03e-67 yerC - - S - - - protein conserved in bacteria
NPDJDOHC_03158 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NPDJDOHC_03159 1.51e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NPDJDOHC_03160 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NPDJDOHC_03161 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPDJDOHC_03162 2.74e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NPDJDOHC_03163 5.83e-254 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NPDJDOHC_03164 5.01e-159 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NPDJDOHC_03165 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPDJDOHC_03166 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPDJDOHC_03167 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPDJDOHC_03168 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPDJDOHC_03169 1.63e-199 yerO - - K - - - Transcriptional regulator
NPDJDOHC_03170 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NPDJDOHC_03171 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPDJDOHC_03172 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPDJDOHC_03173 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
NPDJDOHC_03174 4.67e-299 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NPDJDOHC_03175 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NPDJDOHC_03177 2.53e-286 - - - V ko:K07451 - ko00000,ko01000,ko02048 Domain of unknown function (DUF3578)
NPDJDOHC_03178 1.42e-118 - - - S - - - Protein of unknown function, DUF600
NPDJDOHC_03179 2.84e-108 - - - S - - - Protein of unknown function, DUF600
NPDJDOHC_03180 1.06e-110 - - - S - - - Protein of unknown function, DUF600
NPDJDOHC_03181 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
NPDJDOHC_03182 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
NPDJDOHC_03184 4.61e-61 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NPDJDOHC_03185 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
NPDJDOHC_03186 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NPDJDOHC_03187 3.17e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
NPDJDOHC_03188 5.92e-05 - - - - - - - -
NPDJDOHC_03189 8.99e-157 yetF - - S - - - membrane
NPDJDOHC_03190 5.49e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NPDJDOHC_03191 2.27e-86 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPDJDOHC_03192 7.98e-200 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPDJDOHC_03193 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
NPDJDOHC_03194 1.82e-73 - - - H - - - riboflavin kinase activity
NPDJDOHC_03195 1.54e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NPDJDOHC_03196 2.08e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NPDJDOHC_03197 2.19e-267 yetM - - CH - - - FAD binding domain
NPDJDOHC_03198 2.38e-252 yetN - - S - - - Protein of unknown function (DUF3900)
NPDJDOHC_03199 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NPDJDOHC_03201 5.83e-67 - - - K - - - Winged helix DNA-binding domain
NPDJDOHC_03202 7.9e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NPDJDOHC_03203 2.27e-163 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NPDJDOHC_03204 4.77e-130 - - - S - - - protein homooligomerization
NPDJDOHC_03205 1.98e-167 - - - - - - - -
NPDJDOHC_03206 7.91e-247 - - - S - - - ATP diphosphatase activity
NPDJDOHC_03207 0.0 - - - S ko:K09136 - ko00000,ko03009 YcaO cyclodehydratase, ATP-ad Mg2+-binding
NPDJDOHC_03208 5.49e-196 - - - C - - - Nitroreductase family
NPDJDOHC_03209 3.67e-150 - - - S - - - CAAX protease self-immunity
NPDJDOHC_03210 7.44e-190 - 2.1.1.163, 2.1.1.201 - Q ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 methyltransferase
NPDJDOHC_03212 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NPDJDOHC_03213 6.17e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NPDJDOHC_03214 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NPDJDOHC_03215 6.89e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NPDJDOHC_03216 5.31e-287 yfnE - - S - - - Glycosyltransferase like family 2
NPDJDOHC_03217 1.46e-240 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NPDJDOHC_03218 2.7e-278 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_03219 4.33e-315 yfnA - - E ko:K03294 - ko00000 amino acid
NPDJDOHC_03220 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPDJDOHC_03221 2.85e-169 yfmS - - NT - - - chemotaxis protein
NPDJDOHC_03222 2.1e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NPDJDOHC_03223 9.2e-270 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NPDJDOHC_03224 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPDJDOHC_03225 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NPDJDOHC_03226 1.25e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NPDJDOHC_03227 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPDJDOHC_03228 3.91e-268 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NPDJDOHC_03229 3.25e-26 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
NPDJDOHC_03230 1.19e-43 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
NPDJDOHC_03231 2.54e-243 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NPDJDOHC_03232 4.44e-31 - - - S - - - Protein of unknown function (DUF3212)
NPDJDOHC_03233 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
NPDJDOHC_03234 8.27e-311 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NPDJDOHC_03235 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NPDJDOHC_03236 7.54e-41 - - - Q - - - PFAM Collagen triple helix
NPDJDOHC_03237 3.19e-117 - - - Q - - - PFAM Collagen triple helix
NPDJDOHC_03238 2.96e-188 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
NPDJDOHC_03239 2.34e-121 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
NPDJDOHC_03240 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NPDJDOHC_03241 8.33e-156 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NPDJDOHC_03242 8.33e-228 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NPDJDOHC_03243 2.01e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NPDJDOHC_03244 5.08e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NPDJDOHC_03245 1.49e-279 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NPDJDOHC_03246 3.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NPDJDOHC_03247 5.28e-160 yflK - - S - - - protein conserved in bacteria
NPDJDOHC_03248 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
NPDJDOHC_03249 1.98e-26 yflI - - - - - - -
NPDJDOHC_03250 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
NPDJDOHC_03251 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NPDJDOHC_03252 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NPDJDOHC_03253 7.03e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NPDJDOHC_03254 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NPDJDOHC_03255 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NPDJDOHC_03256 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NPDJDOHC_03257 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
NPDJDOHC_03258 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
NPDJDOHC_03259 3.27e-315 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_03260 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NPDJDOHC_03261 2.89e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NPDJDOHC_03262 1.45e-158 frp - - C - - - nitroreductase
NPDJDOHC_03263 6e-167 yibF - - S - - - YibE/F-like protein
NPDJDOHC_03264 8.4e-260 yibE - - S - - - YibE/F-like protein
NPDJDOHC_03266 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NPDJDOHC_03267 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NPDJDOHC_03268 1.58e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NPDJDOHC_03269 6.12e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPDJDOHC_03270 1.82e-177 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPDJDOHC_03271 8.51e-253 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_03272 2.53e-42 yfkK - - S - - - Belongs to the UPF0435 family
NPDJDOHC_03273 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPDJDOHC_03274 1.29e-70 yfkI - - S - - - gas vesicle protein
NPDJDOHC_03275 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NPDJDOHC_03276 6.71e-12 - - - - - - - -
NPDJDOHC_03277 2.61e-281 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_03278 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NPDJDOHC_03279 5.66e-186 yfkD - - S - - - YfkD-like protein
NPDJDOHC_03280 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
NPDJDOHC_03281 2.06e-282 yfkA - - S - - - YfkB-like domain
NPDJDOHC_03282 7.99e-37 yfjT - - - - - - -
NPDJDOHC_03283 1.07e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NPDJDOHC_03284 2.05e-195 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NPDJDOHC_03286 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NPDJDOHC_03287 7.59e-212 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPDJDOHC_03288 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPDJDOHC_03289 2.97e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPDJDOHC_03290 1.42e-122 yfjM - - S - - - Psort location Cytoplasmic, score
NPDJDOHC_03291 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPDJDOHC_03292 9.2e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPDJDOHC_03293 6.13e-278 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPDJDOHC_03294 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPDJDOHC_03295 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NPDJDOHC_03296 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NPDJDOHC_03297 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPDJDOHC_03298 2.69e-179 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NPDJDOHC_03299 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NPDJDOHC_03300 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
NPDJDOHC_03301 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NPDJDOHC_03302 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NPDJDOHC_03303 1.36e-82 yfiD3 - - S - - - DoxX
NPDJDOHC_03304 3.46e-207 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NPDJDOHC_03305 2.03e-221 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPDJDOHC_03306 5.62e-126 padR - - K - - - transcriptional
NPDJDOHC_03307 1.26e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NPDJDOHC_03308 7.2e-241 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NPDJDOHC_03309 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NPDJDOHC_03310 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NPDJDOHC_03311 1.24e-132 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NPDJDOHC_03312 0.0 yfiU - - EGP - - - the major facilitator superfamily
NPDJDOHC_03313 1.38e-108 yfiV - - K - - - transcriptional
NPDJDOHC_03314 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPDJDOHC_03315 3.35e-214 yfhB - - S - - - PhzF family
NPDJDOHC_03316 8.22e-138 yfhC - - C - - - nitroreductase
NPDJDOHC_03317 3.61e-34 yfhD - - S - - - YfhD-like protein
NPDJDOHC_03319 1.08e-217 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NPDJDOHC_03320 3.14e-183 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NPDJDOHC_03321 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
NPDJDOHC_03322 1.42e-268 yfhI - - EGP - - - -transporter
NPDJDOHC_03324 2.1e-217 mpr - - M - - - Belongs to the peptidase S1B family
NPDJDOHC_03325 3.12e-60 yfhJ - - S - - - WVELL protein
NPDJDOHC_03326 2.94e-124 yfhK - - T - - - Bacterial SH3 domain homologues
NPDJDOHC_03327 6.28e-59 yfhL - - S - - - SdpI/YhfL protein family
NPDJDOHC_03328 5.82e-220 - - - S - - - Alpha/beta hydrolase family
NPDJDOHC_03329 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NPDJDOHC_03330 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NPDJDOHC_03331 2.52e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NPDJDOHC_03332 3.2e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NPDJDOHC_03333 2.54e-50 yfhS - - - - - - -
NPDJDOHC_03334 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPDJDOHC_03335 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NPDJDOHC_03336 1.4e-49 ygaB - - S - - - YgaB-like protein
NPDJDOHC_03337 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NPDJDOHC_03338 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NPDJDOHC_03339 1.58e-240 ygaE - - S - - - Membrane
NPDJDOHC_03340 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NPDJDOHC_03341 3.41e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NPDJDOHC_03342 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NPDJDOHC_03343 4.67e-75 ygzB - - S - - - UPF0295 protein
NPDJDOHC_03344 2.75e-213 ygxA - - S - - - Nucleotidyltransferase-like
NPDJDOHC_03345 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPDJDOHC_03346 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPDJDOHC_03347 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
NPDJDOHC_03348 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPDJDOHC_03349 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NPDJDOHC_03350 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPDJDOHC_03351 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPDJDOHC_03352 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPDJDOHC_03353 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPDJDOHC_03354 8.37e-145 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NPDJDOHC_03355 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPDJDOHC_03356 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPDJDOHC_03357 1.68e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NPDJDOHC_03358 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NPDJDOHC_03359 1.18e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NPDJDOHC_03360 1.23e-190 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NPDJDOHC_03361 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
NPDJDOHC_03362 1.86e-114 yhhY - - K - - - FR47-like protein
NPDJDOHC_03363 1.67e-225 yyaD - - S - - - Membrane
NPDJDOHC_03364 3.13e-46 yyzM - - S - - - protein conserved in bacteria
NPDJDOHC_03365 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPDJDOHC_03366 2.3e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPDJDOHC_03367 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NPDJDOHC_03368 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPDJDOHC_03369 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPDJDOHC_03370 4.09e-142 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NPDJDOHC_03371 1.55e-133 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPDJDOHC_03372 1.52e-189 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NPDJDOHC_03373 1.19e-232 ccpB - - K - - - Transcriptional regulator
NPDJDOHC_03374 5.93e-89 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPDJDOHC_03375 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NPDJDOHC_03376 7.58e-213 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NPDJDOHC_03377 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NPDJDOHC_03378 0.0 - 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NPDJDOHC_03380 5.52e-92 ynaF - - - - - - -
NPDJDOHC_03381 1.02e-106 - - - - - - - -
NPDJDOHC_03382 9.78e-38 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
NPDJDOHC_03383 7.43e-130 - - - - - - - -
NPDJDOHC_03384 3.96e-184 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NPDJDOHC_03385 6.24e-214 - - - K - - - Transcriptional regulator
NPDJDOHC_03386 7.04e-89 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NPDJDOHC_03387 2.02e-212 - - - M - - - Domain of Unknown Function (DUF1259)
NPDJDOHC_03388 6.58e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
NPDJDOHC_03389 3.2e-100 yybA - - K - - - transcriptional
NPDJDOHC_03390 3.4e-197 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NPDJDOHC_03391 8.26e-91 - - - K - - - Winged helix DNA-binding domain
NPDJDOHC_03392 1.7e-148 ydgI - - C - - - nitroreductase
NPDJDOHC_03393 9.61e-75 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NPDJDOHC_03394 9.22e-213 yybE - - K - - - Transcriptional regulator
NPDJDOHC_03395 3.29e-279 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NPDJDOHC_03396 1.13e-129 - - - E - - - LysE type translocator
NPDJDOHC_03397 4.38e-209 - - - K - - - LysR substrate binding domain
NPDJDOHC_03398 4.47e-22 - - - G - - - Major Facilitator Superfamily
NPDJDOHC_03399 5.5e-209 - - - G - - - Major Facilitator Superfamily
NPDJDOHC_03400 5.75e-119 - - - S - - - PFAM DinB family protein
NPDJDOHC_03401 4.15e-153 - - - K - - - FCD domain
NPDJDOHC_03402 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NPDJDOHC_03403 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NPDJDOHC_03404 2.14e-199 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPDJDOHC_03405 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NPDJDOHC_03406 4.56e-87 yybR - - K - - - Transcriptional regulator
NPDJDOHC_03407 1.88e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
NPDJDOHC_03409 3.68e-206 yybS - - S - - - membrane
NPDJDOHC_03410 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NPDJDOHC_03411 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NPDJDOHC_03412 1.99e-165 - - - KLT - - - COG0515 Serine threonine protein kinase
NPDJDOHC_03413 1.85e-158 - - - S - - - GlcNAc-PI de-N-acetylase
NPDJDOHC_03414 0.0 - - - M - - - Glycosyltransferase Family 4
NPDJDOHC_03415 2.05e-300 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
NPDJDOHC_03416 1.2e-263 - - - S - - - Ecdysteroid kinase
NPDJDOHC_03417 1.55e-315 - - - M - - - Glycosyltransferase Family 4
NPDJDOHC_03418 7.2e-56 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase activity
NPDJDOHC_03419 3.6e-25 yycC - - K - - - YycC-like protein
NPDJDOHC_03421 1.88e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NPDJDOHC_03422 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NPDJDOHC_03423 4.87e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPDJDOHC_03424 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPDJDOHC_03429 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_03430 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_03431 0.0 yycH - - S - - - protein conserved in bacteria
NPDJDOHC_03432 1.77e-197 yycI - - S - - - protein conserved in bacteria
NPDJDOHC_03433 9.84e-192 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NPDJDOHC_03434 4.87e-280 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPDJDOHC_03435 8.72e-15 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_03436 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NPDJDOHC_03437 3.19e-248 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
NPDJDOHC_03438 0.0 - - - - - - - -
NPDJDOHC_03439 4.27e-257 - - - S - - - Major Facilitator Superfamily
NPDJDOHC_03440 0.0 - - - S - - - ABC transporter
NPDJDOHC_03441 4.53e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
NPDJDOHC_03442 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NPDJDOHC_03443 6.09e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NPDJDOHC_03444 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NPDJDOHC_03445 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NPDJDOHC_03446 1.47e-265 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NPDJDOHC_03448 4.31e-115 yycN - - K - - - Acetyltransferase
NPDJDOHC_03449 3.31e-237 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NPDJDOHC_03450 8.65e-174 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NPDJDOHC_03451 1.65e-286 yycP - - - - - - -
NPDJDOHC_03454 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPDJDOHC_03455 1.91e-241 - - - - - - - -
NPDJDOHC_03456 1.72e-305 - - - T - - - Putative serine esterase (DUF676)
NPDJDOHC_03457 9.72e-11 - - - - - - - -
NPDJDOHC_03458 0.0 - - - L - - - ATPase involved in DNA repair
NPDJDOHC_03460 5.15e-08 - - - L - - - resolvase
NPDJDOHC_03462 3.74e-242 - - - S - - - Fusaric acid resistance protein-like
NPDJDOHC_03463 8.91e-248 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NPDJDOHC_03464 7.31e-126 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NPDJDOHC_03465 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NPDJDOHC_03466 9.17e-205 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NPDJDOHC_03467 4.71e-112 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NPDJDOHC_03468 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NPDJDOHC_03469 5.26e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NPDJDOHC_03470 1.44e-294 - - - S - - - Fic/DOC family
NPDJDOHC_03471 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NPDJDOHC_03472 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NPDJDOHC_03473 5.06e-167 - - - E - - - Ring-cleavage extradiol dioxygenase
NPDJDOHC_03474 2.33e-98 yxaI - - S - - - membrane protein domain
NPDJDOHC_03475 1.07e-262 - - - EGP - - - Major Facilitator Superfamily
NPDJDOHC_03476 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NPDJDOHC_03477 3.04e-86 - - - S - - - Family of unknown function (DUF5391)
NPDJDOHC_03478 8.79e-192 yxaL - - S - - - PQQ-like domain
NPDJDOHC_03479 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NPDJDOHC_03480 2.61e-282 yxbF - - K - - - Bacterial regulatory proteins, tetR family
NPDJDOHC_03481 3.84e-259 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NPDJDOHC_03482 3.03e-257 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_03483 7.82e-134 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPDJDOHC_03484 1.51e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NPDJDOHC_03485 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NPDJDOHC_03486 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPDJDOHC_03487 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NPDJDOHC_03488 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NPDJDOHC_03489 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPDJDOHC_03490 6.21e-203 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NPDJDOHC_03491 2.92e-233 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NPDJDOHC_03492 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NPDJDOHC_03493 3.53e-227 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NPDJDOHC_03494 3.29e-297 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NPDJDOHC_03495 2.68e-252 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NPDJDOHC_03496 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NPDJDOHC_03497 8.8e-203 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NPDJDOHC_03498 1.46e-206 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NPDJDOHC_03499 1.89e-170 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NPDJDOHC_03500 1.36e-167 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
NPDJDOHC_03501 3.2e-212 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_03502 6.65e-178 yvrH - - T - - - Transcriptional regulator
NPDJDOHC_03503 0.0 - - - T - - - Histidine kinase
NPDJDOHC_03504 4.84e-161 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDJDOHC_03505 6.81e-225 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NPDJDOHC_03506 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NPDJDOHC_03507 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NPDJDOHC_03508 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
NPDJDOHC_03509 9.5e-208 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NPDJDOHC_03510 6.1e-204 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NPDJDOHC_03511 1.02e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NPDJDOHC_03512 4.3e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPDJDOHC_03513 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPDJDOHC_03514 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPDJDOHC_03515 3.42e-68 yqzD - - - - - - -
NPDJDOHC_03516 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NPDJDOHC_03517 8e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPDJDOHC_03518 5.38e-11 yqgO - - - - - - -
NPDJDOHC_03519 3.9e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NPDJDOHC_03520 1.23e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NPDJDOHC_03521 1.3e-286 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NPDJDOHC_03522 1.32e-256 yqgU - - - - - - -
NPDJDOHC_03523 2.99e-65 dglA - - S - - - Thiamine-binding protein
NPDJDOHC_03524 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
NPDJDOHC_03525 5.96e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NPDJDOHC_03526 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NPDJDOHC_03527 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NPDJDOHC_03529 1.5e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPDJDOHC_03530 6.5e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NPDJDOHC_03531 4.53e-239 yqxL - - P - - - Mg2 transporter protein
NPDJDOHC_03532 1.34e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NPDJDOHC_03533 2.62e-239 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NPDJDOHC_03534 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NPDJDOHC_03535 2.37e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
NPDJDOHC_03536 6.31e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NPDJDOHC_03537 9.51e-90 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NPDJDOHC_03538 1.2e-83 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NPDJDOHC_03539 2e-36 yqzE - - S - - - YqzE-like protein
NPDJDOHC_03540 1.69e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
NPDJDOHC_03541 5.91e-159 yqxM - - - ko:K19433 - ko00000 -
NPDJDOHC_03542 3.27e-103 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NPDJDOHC_03543 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NPDJDOHC_03544 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NPDJDOHC_03545 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NPDJDOHC_03546 1.11e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
NPDJDOHC_03547 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NPDJDOHC_03548 2.44e-266 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NPDJDOHC_03549 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NPDJDOHC_03550 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NPDJDOHC_03551 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NPDJDOHC_03552 6.72e-206 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NPDJDOHC_03553 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NPDJDOHC_03554 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NPDJDOHC_03555 7.65e-83 yqhP - - - - - - -
NPDJDOHC_03556 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
NPDJDOHC_03557 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
NPDJDOHC_03558 1.27e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NPDJDOHC_03559 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPDJDOHC_03560 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
NPDJDOHC_03561 5.39e-222 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NPDJDOHC_03562 5.93e-113 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NPDJDOHC_03563 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NPDJDOHC_03564 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NPDJDOHC_03565 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NPDJDOHC_03566 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NPDJDOHC_03567 3.48e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NPDJDOHC_03568 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NPDJDOHC_03569 2.32e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPDJDOHC_03570 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NPDJDOHC_03571 1.93e-87 yqhY - - S - - - protein conserved in bacteria
NPDJDOHC_03572 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPDJDOHC_03573 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPDJDOHC_03574 6.82e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPDJDOHC_03575 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPDJDOHC_03576 8.13e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NPDJDOHC_03577 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPDJDOHC_03578 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NPDJDOHC_03579 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NPDJDOHC_03580 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NPDJDOHC_03581 3.22e-306 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NPDJDOHC_03582 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NPDJDOHC_03583 5.23e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPDJDOHC_03586 3.37e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NPDJDOHC_03588 6.93e-147 - - - K - - - Protein of unknown function (DUF1232)
NPDJDOHC_03589 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
NPDJDOHC_03591 1.69e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NPDJDOHC_03592 1.9e-175 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NPDJDOHC_03593 1.38e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NPDJDOHC_03594 3.72e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NPDJDOHC_03595 1.93e-264 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NPDJDOHC_03596 1.85e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NPDJDOHC_03597 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NPDJDOHC_03598 6.92e-206 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NPDJDOHC_03599 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
NPDJDOHC_03600 0.0 bkdR - - KT - - - Transcriptional regulator
NPDJDOHC_03601 2.03e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NPDJDOHC_03602 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NPDJDOHC_03603 1.2e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NPDJDOHC_03604 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPDJDOHC_03605 8.24e-224 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPDJDOHC_03606 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPDJDOHC_03607 7.91e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPDJDOHC_03608 1.48e-219 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPDJDOHC_03609 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
NPDJDOHC_03610 5.83e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NPDJDOHC_03611 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NPDJDOHC_03612 2.58e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NPDJDOHC_03613 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NPDJDOHC_03614 5.47e-125 yqjB - - S - - - protein conserved in bacteria
NPDJDOHC_03616 9.74e-98 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NPDJDOHC_03617 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPDJDOHC_03618 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NPDJDOHC_03619 1.01e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPDJDOHC_03620 1.3e-34 yqzJ - - - - - - -
NPDJDOHC_03621 1.16e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPDJDOHC_03622 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPDJDOHC_03623 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPDJDOHC_03624 1.18e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPDJDOHC_03625 2.72e-190 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPDJDOHC_03626 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NPDJDOHC_03627 5.5e-67 - - - S - - - GlpM protein
NPDJDOHC_03628 1.36e-212 - - - K - - - LysR substrate binding domain
NPDJDOHC_03629 5.26e-123 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NPDJDOHC_03630 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NPDJDOHC_03633 0.0 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPDJDOHC_03634 4.81e-169 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NPDJDOHC_03635 6.38e-183 pdaB - - G - - - Polysaccharide deacetylase
NPDJDOHC_03636 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NPDJDOHC_03637 6.81e-103 gerD - - - ko:K06294 - ko00000 -
NPDJDOHC_03638 2.21e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NPDJDOHC_03639 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NPDJDOHC_03640 3.22e-103 ybaK - - S - - - Protein of unknown function (DUF2521)
NPDJDOHC_03641 8.36e-113 yizA - - S - - - Damage-inducible protein DinB
NPDJDOHC_03642 7.48e-187 ybaJ - - Q - - - Methyltransferase domain
NPDJDOHC_03643 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NPDJDOHC_03644 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPDJDOHC_03645 9.1e-184 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPDJDOHC_03646 1.37e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPDJDOHC_03647 1.26e-192 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPDJDOHC_03648 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPDJDOHC_03649 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NPDJDOHC_03650 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPDJDOHC_03651 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPDJDOHC_03652 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPDJDOHC_03653 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NPDJDOHC_03654 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPDJDOHC_03655 1.4e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NPDJDOHC_03656 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPDJDOHC_03657 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPDJDOHC_03658 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NPDJDOHC_03659 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NPDJDOHC_03660 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPDJDOHC_03661 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPDJDOHC_03662 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPDJDOHC_03663 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPDJDOHC_03664 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPDJDOHC_03665 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPDJDOHC_03666 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPDJDOHC_03667 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPDJDOHC_03668 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPDJDOHC_03669 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NPDJDOHC_03670 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPDJDOHC_03671 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPDJDOHC_03672 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPDJDOHC_03673 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPDJDOHC_03674 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPDJDOHC_03675 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPDJDOHC_03676 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NPDJDOHC_03677 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPDJDOHC_03678 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NPDJDOHC_03679 1.78e-243 ybaC - - S - - - Alpha/beta hydrolase family
NPDJDOHC_03680 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPDJDOHC_03681 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPDJDOHC_03682 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPDJDOHC_03683 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPDJDOHC_03684 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NPDJDOHC_03685 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPDJDOHC_03686 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPDJDOHC_03687 4.37e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NPDJDOHC_03688 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPDJDOHC_03689 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPDJDOHC_03690 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPDJDOHC_03691 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPDJDOHC_03692 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NPDJDOHC_03693 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPDJDOHC_03694 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NPDJDOHC_03695 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NPDJDOHC_03696 2.48e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPDJDOHC_03697 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPDJDOHC_03698 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NPDJDOHC_03699 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NPDJDOHC_03700 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPDJDOHC_03701 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NPDJDOHC_03702 3.02e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NPDJDOHC_03703 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NPDJDOHC_03704 7.66e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NPDJDOHC_03705 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPDJDOHC_03706 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NPDJDOHC_03707 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NPDJDOHC_03708 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NPDJDOHC_03709 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NPDJDOHC_03710 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NPDJDOHC_03711 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPDJDOHC_03712 6.1e-40 yazB - - K - - - transcriptional
NPDJDOHC_03713 8.2e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NPDJDOHC_03714 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPDJDOHC_03715 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NPDJDOHC_03716 1.53e-210 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NPDJDOHC_03717 1.31e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NPDJDOHC_03718 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPDJDOHC_03719 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NPDJDOHC_03720 3.86e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NPDJDOHC_03721 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPDJDOHC_03722 1.41e-178 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NPDJDOHC_03723 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPDJDOHC_03724 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NPDJDOHC_03725 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPDJDOHC_03726 1.4e-237 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NPDJDOHC_03727 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NPDJDOHC_03728 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NPDJDOHC_03731 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NPDJDOHC_03732 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NPDJDOHC_03733 1.18e-134 yabQ - - S - - - spore cortex biosynthesis protein
NPDJDOHC_03734 5.47e-66 yabP - - S - - - Sporulation protein YabP
NPDJDOHC_03735 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NPDJDOHC_03736 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NPDJDOHC_03737 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPDJDOHC_03738 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NPDJDOHC_03739 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPDJDOHC_03740 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
NPDJDOHC_03741 6.07e-137 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPDJDOHC_03742 3.72e-138 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NPDJDOHC_03743 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPDJDOHC_03744 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPDJDOHC_03745 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NPDJDOHC_03746 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NPDJDOHC_03747 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NPDJDOHC_03748 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NPDJDOHC_03749 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
NPDJDOHC_03750 5.32e-53 veg - - S - - - protein conserved in bacteria
NPDJDOHC_03751 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
NPDJDOHC_03752 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPDJDOHC_03753 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPDJDOHC_03754 2.49e-310 yabE - - T - - - protein conserved in bacteria
NPDJDOHC_03755 2.22e-186 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NPDJDOHC_03756 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPDJDOHC_03757 2.69e-30 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NPDJDOHC_03758 4.93e-211 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPDJDOHC_03759 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NPDJDOHC_03760 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NPDJDOHC_03761 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
NPDJDOHC_03762 9e-189 yaaT - - S - - - stage 0 sporulation protein
NPDJDOHC_03763 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NPDJDOHC_03764 1.04e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NPDJDOHC_03765 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
NPDJDOHC_03766 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPDJDOHC_03767 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NPDJDOHC_03768 4.58e-249 yaaN - - P - - - Belongs to the TelA family
NPDJDOHC_03769 1.24e-137 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NPDJDOHC_03770 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
NPDJDOHC_03771 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_03772 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_03773 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NPDJDOHC_03774 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NPDJDOHC_03775 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
NPDJDOHC_03776 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPDJDOHC_03777 2.41e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPDJDOHC_03778 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPDJDOHC_03779 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPDJDOHC_03780 1.05e-130 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NPDJDOHC_03781 3.03e-279 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NPDJDOHC_03782 1.41e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NPDJDOHC_03783 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NPDJDOHC_03785 4.55e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NPDJDOHC_03786 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPDJDOHC_03787 4.94e-140 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NPDJDOHC_03788 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NPDJDOHC_03789 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NPDJDOHC_03790 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NPDJDOHC_03791 3e-236 yaaC - - S - - - YaaC-like Protein
NPDJDOHC_03792 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_03793 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_03794 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDJDOHC_03795 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)