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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HEKEIKFC_00001	6.26e-156	yvbI	-	-	M	-	-	-	Membrane
HEKEIKFC_00002	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HEKEIKFC_00003	1.11e-106	yvbK	-	-	K	-	-	-	acetyltransferase
HEKEIKFC_00004	2.68e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HEKEIKFC_00005	2.8e-228	-	-	-	-	-	-	-	-
HEKEIKFC_00006	5.24e-161	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HEKEIKFC_00007	1.67e-184	-	-	-	C	-	-	-	WbqC-like protein family
HEKEIKFC_00008	3.92e-192	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
HEKEIKFC_00009	8.4e-298	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEKEIKFC_00010	2.99e-220	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
HEKEIKFC_00011	2.79e-277	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HEKEIKFC_00012	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEKEIKFC_00013	1.78e-305	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HEKEIKFC_00014	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEKEIKFC_00015	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HEKEIKFC_00016	2.58e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEKEIKFC_00017	3.98e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HEKEIKFC_00018	4.7e-237	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEKEIKFC_00019	2.95e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEKEIKFC_00021	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEKEIKFC_00022	3.31e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HEKEIKFC_00024	1.71e-241	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEKEIKFC_00025	3.72e-161	yvbU	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00026	1.58e-111	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HEKEIKFC_00027	4.71e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEKEIKFC_00028	0.0	-	-	-	-	-	-	-	-
HEKEIKFC_00029	3.55e-231	yhjM	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00030	8.98e-149	-	-	-	S	ko:K07149	-	ko00000	Membrane
HEKEIKFC_00031	2.09e-213	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HEKEIKFC_00032	1.56e-194	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
HEKEIKFC_00033	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HEKEIKFC_00034	1.37e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HEKEIKFC_00035	1.23e-173	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEKEIKFC_00036	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HEKEIKFC_00037	2.14e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEKEIKFC_00038	2.25e-284	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEKEIKFC_00039	3.1e-156	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HEKEIKFC_00040	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HEKEIKFC_00041	6.55e-309	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HEKEIKFC_00042	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
HEKEIKFC_00043	8.14e-240	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HEKEIKFC_00044	3.31e-283	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HEKEIKFC_00045	5.73e-79	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HEKEIKFC_00046	1.92e-140	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEKEIKFC_00047	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEKEIKFC_00048	2.46e-248	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEKEIKFC_00049	7.76e-259	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HEKEIKFC_00050	6.53e-249	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HEKEIKFC_00051	1.71e-262	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HEKEIKFC_00052	3.51e-272	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEKEIKFC_00053	3.89e-206	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEKEIKFC_00054	2.39e-275	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HEKEIKFC_00055	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEKEIKFC_00056	7.67e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HEKEIKFC_00057	4.08e-156	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HEKEIKFC_00058	6.96e-100	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HEKEIKFC_00059	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HEKEIKFC_00060	3.85e-125	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HEKEIKFC_00061	7.2e-144	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HEKEIKFC_00062	6.12e-116	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEKEIKFC_00063	1.01e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HEKEIKFC_00064	6.65e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEKEIKFC_00065	3.36e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEKEIKFC_00066	1.54e-50	-	-	-	IU	-	-	-	Lipase (class 3)
HEKEIKFC_00067	1.43e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEKEIKFC_00068	4.02e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEKEIKFC_00069	4.38e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEKEIKFC_00070	0.0	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HEKEIKFC_00071	3.08e-44	-	-	-	-	-	-	-	-
HEKEIKFC_00073	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HEKEIKFC_00074	2.01e-285	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HEKEIKFC_00075	1.57e-234	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HEKEIKFC_00076	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEKEIKFC_00077	3.9e-209	yraN	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00078	1e-270	yraM	-	-	S	-	-	-	PrpF protein
HEKEIKFC_00079	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HEKEIKFC_00081	3.78e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HEKEIKFC_00082	1.3e-69	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HEKEIKFC_00083	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HEKEIKFC_00084	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HEKEIKFC_00085	6.9e-232	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEKEIKFC_00086	5.54e-105	-	-	-	M	-	-	-	Ribonuclease
HEKEIKFC_00087	8.09e-183	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HEKEIKFC_00088	2.76e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HEKEIKFC_00089	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HEKEIKFC_00090	8.99e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HEKEIKFC_00091	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HEKEIKFC_00092	5.15e-113	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEKEIKFC_00093	8.99e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEKEIKFC_00094	7.1e-202	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HEKEIKFC_00095	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEKEIKFC_00096	2.63e-243	sasA	-	-	T	-	-	-	Histidine kinase
HEKEIKFC_00097	3.99e-158	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_00098	5.51e-73	-	-	-	-	-	-	-	-
HEKEIKFC_00099	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HEKEIKFC_00100	8.12e-144	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HEKEIKFC_00101	1.38e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEKEIKFC_00102	9.3e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEKEIKFC_00103	4.87e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEKEIKFC_00104	1.17e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HEKEIKFC_00105	2.61e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEKEIKFC_00106	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEKEIKFC_00107	6.03e-270	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEKEIKFC_00108	4.16e-177	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HEKEIKFC_00109	4.65e-95	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HEKEIKFC_00110	8.12e-158	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEKEIKFC_00111	1.39e-190	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEKEIKFC_00112	6e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEKEIKFC_00113	3.06e-282	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEKEIKFC_00114	9.04e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEKEIKFC_00115	1.75e-170	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HEKEIKFC_00116	1.27e-135	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HEKEIKFC_00117	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HEKEIKFC_00118	7.66e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HEKEIKFC_00119	8.1e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HEKEIKFC_00120	3.2e-218	yvlB	-	-	S	-	-	-	Putative adhesin
HEKEIKFC_00121	4.87e-66	yvlA	-	-	-	-	-	-	-
HEKEIKFC_00122	2.97e-50	yvkN	-	-	-	-	-	-	-
HEKEIKFC_00123	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEKEIKFC_00124	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEKEIKFC_00125	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_00126	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HEKEIKFC_00127	2.32e-144	yvkB	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00128	8.04e-296	yvkA	-	-	P	-	-	-	-transporter
HEKEIKFC_00129	4.5e-233	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HEKEIKFC_00130	8.77e-282	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEKEIKFC_00131	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
HEKEIKFC_00132	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HEKEIKFC_00133	4.92e-304	ywoF	-	-	P	-	-	-	Right handed beta helix region
HEKEIKFC_00134	2.48e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEKEIKFC_00135	5.86e-157	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HEKEIKFC_00136	5.11e-59	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HEKEIKFC_00137	4.82e-192	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEKEIKFC_00138	6.64e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEKEIKFC_00139	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEKEIKFC_00140	3.94e-133	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEKEIKFC_00141	1.35e-89	-	-	-	-	-	-	-	-
HEKEIKFC_00142	5.61e-10	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HEKEIKFC_00143	5.79e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HEKEIKFC_00144	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEKEIKFC_00145	1.97e-139	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEKEIKFC_00146	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEKEIKFC_00147	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HEKEIKFC_00148	2.8e-108	yviE	-	-	-	-	-	-	-
HEKEIKFC_00149	5.69e-207	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HEKEIKFC_00150	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HEKEIKFC_00151	2.2e-105	yvyG	-	-	NOU	-	-	-	FlgN protein
HEKEIKFC_00152	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HEKEIKFC_00153	1.1e-97	yvyF	-	-	S	-	-	-	flagellar protein
HEKEIKFC_00154	2.89e-99	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HEKEIKFC_00155	3.56e-57	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HEKEIKFC_00156	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEKEIKFC_00157	8.45e-202	degV	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_00158	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEKEIKFC_00159	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HEKEIKFC_00160	3.43e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HEKEIKFC_00161	1.9e-230	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00162	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HEKEIKFC_00163	2.22e-301	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HEKEIKFC_00164	2.82e-185	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HEKEIKFC_00165	1.22e-148	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HEKEIKFC_00166	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HEKEIKFC_00167	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEKEIKFC_00168	5.31e-284	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HEKEIKFC_00169	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEKEIKFC_00170	4.22e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEKEIKFC_00171	1.99e-264	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEKEIKFC_00172	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HEKEIKFC_00173	3.45e-40	-	-	-	-	-	-	-	-
HEKEIKFC_00174	2.33e-179	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEKEIKFC_00175	1.2e-234	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEKEIKFC_00176	3.04e-200	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HEKEIKFC_00177	9.74e-238	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEKEIKFC_00178	5.47e-174	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HEKEIKFC_00179	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEKEIKFC_00180	7.22e-305	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
HEKEIKFC_00181	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HEKEIKFC_00182	2.6e-183	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEKEIKFC_00183	1.21e-266	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEKEIKFC_00184	9.86e-169	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEKEIKFC_00185	5.74e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEKEIKFC_00186	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HEKEIKFC_00187	2.58e-253	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HEKEIKFC_00188	1.81e-273	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HEKEIKFC_00189	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
HEKEIKFC_00190	3.45e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEKEIKFC_00191	2.3e-229	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00192	1.3e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HEKEIKFC_00193	1.82e-76	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HEKEIKFC_00194	5.51e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEKEIKFC_00195	4.04e-29	ywtC	-	-	-	-	-	-	-
HEKEIKFC_00196	1.39e-280	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HEKEIKFC_00197	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HEKEIKFC_00198	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HEKEIKFC_00199	2.54e-241	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HEKEIKFC_00200	4.4e-247	-	-	-	E	-	-	-	Spore germination protein
HEKEIKFC_00201	1.3e-262	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HEKEIKFC_00202	4.28e-228	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HEKEIKFC_00203	5.68e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEKEIKFC_00204	3.24e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEKEIKFC_00205	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEKEIKFC_00206	5.37e-205	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEKEIKFC_00207	2.32e-206	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HEKEIKFC_00208	1.18e-115	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HEKEIKFC_00209	7.13e-123	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HEKEIKFC_00210	5.71e-191	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HEKEIKFC_00211	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HEKEIKFC_00212	2.18e-214	alsR	-	-	K	-	-	-	LysR substrate binding domain
HEKEIKFC_00213	4.73e-301	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEKEIKFC_00214	4.87e-163	ywrJ	-	-	-	-	-	-	-
HEKEIKFC_00215	6.63e-172	cotB	-	-	-	ko:K06325	-	ko00000	-
HEKEIKFC_00216	6.5e-270	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HEKEIKFC_00217	3.39e-25	-	-	-	-	-	-	-	-
HEKEIKFC_00218	1.64e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEKEIKFC_00220	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HEKEIKFC_00221	1.01e-109	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HEKEIKFC_00222	6.69e-129	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HEKEIKFC_00223	2.03e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HEKEIKFC_00224	1.76e-172	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HEKEIKFC_00225	7.91e-120	-	-	-	-	-	-	-	-
HEKEIKFC_00226	6.52e-98	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
HEKEIKFC_00227	8.47e-84	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
HEKEIKFC_00228	9.23e-297	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HEKEIKFC_00229	2.09e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HEKEIKFC_00232	9.83e-191	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HEKEIKFC_00233	5.88e-312	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEKEIKFC_00234	5.03e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HEKEIKFC_00235	6.33e-157	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HEKEIKFC_00236	1.01e-151	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HEKEIKFC_00237	1.74e-21	-	-	-	-	-	-	-	-
HEKEIKFC_00238	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HEKEIKFC_00239	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEKEIKFC_00240	7.5e-202	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HEKEIKFC_00241	1.18e-181	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HEKEIKFC_00242	5.13e-77	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HEKEIKFC_00243	4.49e-82	ywpG	-	-	-	-	-	-	-
HEKEIKFC_00244	1.07e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
HEKEIKFC_00245	1.87e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEKEIKFC_00246	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEKEIKFC_00247	3.02e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HEKEIKFC_00248	1.49e-184	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HEKEIKFC_00249	3.46e-172	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HEKEIKFC_00250	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HEKEIKFC_00251	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HEKEIKFC_00252	7.23e-93	ywoH	-	-	K	-	-	-	transcriptional
HEKEIKFC_00253	1.94e-270	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_00254	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HEKEIKFC_00255	2.31e-311	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HEKEIKFC_00256	2.67e-131	yjgF	-	-	Q	-	-	-	Isochorismatase family
HEKEIKFC_00257	1.32e-291	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HEKEIKFC_00258	1.29e-76	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HEKEIKFC_00259	1.11e-262	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEKEIKFC_00260	1.94e-130	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HEKEIKFC_00261	5.45e-94	ywnJ	-	-	S	-	-	-	VanZ like family
HEKEIKFC_00262	1.53e-187	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HEKEIKFC_00263	2.76e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HEKEIKFC_00265	5.15e-90	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HEKEIKFC_00266	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEKEIKFC_00267	1.97e-79	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HEKEIKFC_00268	5.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HEKEIKFC_00269	1.26e-87	ywnA	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00270	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEKEIKFC_00271	1.07e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HEKEIKFC_00272	1.94e-66	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HEKEIKFC_00273	7.2e-18	csbD	-	-	K	-	-	-	CsbD-like
HEKEIKFC_00274	5e-106	ywmF	-	-	S	-	-	-	Peptidase M50
HEKEIKFC_00275	6.28e-116	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEKEIKFC_00276	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEKEIKFC_00277	1.75e-184	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEKEIKFC_00279	1.75e-157	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEKEIKFC_00280	1.36e-146	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEKEIKFC_00281	3.32e-241	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HEKEIKFC_00282	4.75e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEKEIKFC_00283	3.4e-174	ywmB	-	-	S	-	-	-	TATA-box binding
HEKEIKFC_00284	1.3e-44	ywzB	-	-	S	-	-	-	membrane
HEKEIKFC_00285	6.9e-116	ywmA	-	-	-	-	-	-	-
HEKEIKFC_00286	8.24e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HEKEIKFC_00287	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEKEIKFC_00288	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEKEIKFC_00289	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEKEIKFC_00290	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEKEIKFC_00291	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEKEIKFC_00292	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEKEIKFC_00293	5.19e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HEKEIKFC_00294	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HEKEIKFC_00295	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEKEIKFC_00296	5.69e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEKEIKFC_00297	1.5e-124	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HEKEIKFC_00298	6.74e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HEKEIKFC_00299	1.2e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEKEIKFC_00300	3.91e-118	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEKEIKFC_00301	3.08e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEKEIKFC_00302	2.45e-98	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HEKEIKFC_00303	2.99e-149	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HEKEIKFC_00304	8.49e-79	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HEKEIKFC_00306	6.95e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEKEIKFC_00307	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEKEIKFC_00308	9.07e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEKEIKFC_00309	1.48e-123	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HEKEIKFC_00310	1.52e-197	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HEKEIKFC_00311	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HEKEIKFC_00312	5.56e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HEKEIKFC_00313	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HEKEIKFC_00314	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEKEIKFC_00315	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HEKEIKFC_00316	5.55e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEKEIKFC_00317	2.22e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEKEIKFC_00318	5.51e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HEKEIKFC_00319	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HEKEIKFC_00320	8.11e-121	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HEKEIKFC_00321	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEKEIKFC_00322	3.41e-75	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEKEIKFC_00323	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HEKEIKFC_00324	9.92e-285	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HEKEIKFC_00325	3.3e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HEKEIKFC_00326	6.53e-58	ywjC	-	-	-	-	-	-	-
HEKEIKFC_00327	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HEKEIKFC_00328	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEKEIKFC_00329	2.04e-134	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEKEIKFC_00330	1.45e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HEKEIKFC_00331	8.93e-124	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HEKEIKFC_00332	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HEKEIKFC_00333	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEKEIKFC_00334	2.91e-109	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HEKEIKFC_00335	4.34e-178	ywiC	-	-	S	-	-	-	YwiC-like protein
HEKEIKFC_00336	1.33e-167	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HEKEIKFC_00337	1.05e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HEKEIKFC_00338	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HEKEIKFC_00339	1.09e-94	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_00341	5.39e-76	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HEKEIKFC_00342	5.07e-188	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HEKEIKFC_00343	1e-269	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HEKEIKFC_00344	5.77e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEKEIKFC_00346	9.15e-41	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HEKEIKFC_00347	2.41e-45	-	-	-	-	-	-	-	-
HEKEIKFC_00348	1.18e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HEKEIKFC_00350	8.45e-101	-	-	-	CP	-	-	-	Membrane
HEKEIKFC_00353	1.22e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HEKEIKFC_00354	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEKEIKFC_00355	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEKEIKFC_00356	6.08e-106	-	-	-	-	-	-	-	-
HEKEIKFC_00357	9.52e-124	ywhD	-	-	S	-	-	-	YwhD family
HEKEIKFC_00358	2.31e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
HEKEIKFC_00359	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HEKEIKFC_00360	1.02e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00361	5.69e-315	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HEKEIKFC_00362	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
HEKEIKFC_00363	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HEKEIKFC_00364	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HEKEIKFC_00365	2.48e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HEKEIKFC_00366	5.36e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
HEKEIKFC_00367	4.59e-121	-	-	-	S	-	-	-	membrane
HEKEIKFC_00368	1.65e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_00369	7.27e-216	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HEKEIKFC_00372	8.13e-239	-	-	-	-	-	-	-	-
HEKEIKFC_00374	4.86e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HEKEIKFC_00375	3.89e-211	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_00376	6.89e-213	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HEKEIKFC_00377	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HEKEIKFC_00378	4.87e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HEKEIKFC_00379	1.39e-179	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HEKEIKFC_00380	3.14e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HEKEIKFC_00381	9.5e-264	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HEKEIKFC_00382	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HEKEIKFC_00383	1.56e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_00384	9.82e-176	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HEKEIKFC_00385	1.4e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HEKEIKFC_00386	7.84e-284	ywfA	-	-	EGP	-	-	-	-transporter
HEKEIKFC_00387	1.34e-262	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HEKEIKFC_00388	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEKEIKFC_00389	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HEKEIKFC_00390	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEKEIKFC_00391	2.58e-313	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEKEIKFC_00392	6.37e-77	-	-	-	-	-	-	-	-
HEKEIKFC_00393	9.44e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HEKEIKFC_00394	2.74e-207	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEKEIKFC_00395	6.14e-232	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEKEIKFC_00396	1.38e-174	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEKEIKFC_00397	3.66e-229	spsG	-	-	M	-	-	-	Spore Coat
HEKEIKFC_00398	4.11e-171	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HEKEIKFC_00399	1.67e-272	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HEKEIKFC_00400	1.45e-200	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HEKEIKFC_00401	1.39e-279	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HEKEIKFC_00402	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HEKEIKFC_00403	7.44e-183	spsA	-	-	M	-	-	-	Spore Coat
HEKEIKFC_00404	6.51e-88	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEKEIKFC_00405	1.41e-72	ywdK	-	-	S	-	-	-	small membrane protein
HEKEIKFC_00406	3.96e-293	ywdJ	-	-	F	-	-	-	Xanthine uracil
HEKEIKFC_00407	1.57e-62	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HEKEIKFC_00408	7.22e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEKEIKFC_00409	1.34e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HEKEIKFC_00410	4.13e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEKEIKFC_00411	3.52e-26	ywdA	-	-	-	-	-	-	-
HEKEIKFC_00412	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HEKEIKFC_00413	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_00414	1.57e-194	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HEKEIKFC_00416	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEKEIKFC_00417	4.5e-234	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEKEIKFC_00418	1.14e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HEKEIKFC_00419	3.11e-270	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HEKEIKFC_00420	1.51e-100	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HEKEIKFC_00421	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HEKEIKFC_00422	8.22e-85	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HEKEIKFC_00423	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HEKEIKFC_00424	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEKEIKFC_00425	2.21e-228	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HEKEIKFC_00426	5.74e-48	ydaS	-	-	S	-	-	-	membrane
HEKEIKFC_00427	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HEKEIKFC_00428	2.85e-286	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEKEIKFC_00429	1.71e-81	gtcA	-	-	S	-	-	-	GtrA-like protein
HEKEIKFC_00430	6.43e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEKEIKFC_00432	7.5e-168	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
HEKEIKFC_00433	4.9e-172	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
HEKEIKFC_00434	3.47e-142	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HEKEIKFC_00435	4.62e-82	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HEKEIKFC_00436	4.47e-214	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HEKEIKFC_00437	6.77e-145	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEKEIKFC_00438	1.12e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEKEIKFC_00439	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00440	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HEKEIKFC_00441	6.47e-144	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HEKEIKFC_00442	1.07e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HEKEIKFC_00443	1.98e-181	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HEKEIKFC_00444	1.37e-216	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HEKEIKFC_00445	3.08e-286	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HEKEIKFC_00446	1.76e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HEKEIKFC_00447	3.28e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEKEIKFC_00448	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEKEIKFC_00449	2.56e-208	gspA	-	-	M	-	-	-	General stress
HEKEIKFC_00450	1.77e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HEKEIKFC_00451	4.37e-214	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HEKEIKFC_00452	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HEKEIKFC_00453	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_00454	7.34e-293	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HEKEIKFC_00455	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_00456	1.31e-290	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEKEIKFC_00457	7.79e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HEKEIKFC_00458	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEKEIKFC_00459	1.18e-67	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_00460	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEKEIKFC_00461	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HEKEIKFC_00462	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HEKEIKFC_00463	5.36e-144	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HEKEIKFC_00464	7.77e-219	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_00465	4.83e-231	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_00466	2.64e-213	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEKEIKFC_00467	1.91e-78	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HEKEIKFC_00468	6.03e-289	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEKEIKFC_00469	1.18e-66	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_00470	7.89e-66	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_00471	7.31e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEKEIKFC_00472	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEKEIKFC_00473	3.77e-215	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HEKEIKFC_00474	5.91e-234	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEKEIKFC_00475	1.53e-266	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HEKEIKFC_00476	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEKEIKFC_00477	7.89e-246	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HEKEIKFC_00478	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HEKEIKFC_00479	1.77e-200	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEKEIKFC_00480	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HEKEIKFC_00481	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HEKEIKFC_00482	2.16e-239	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HEKEIKFC_00483	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HEKEIKFC_00484	7.85e-288	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HEKEIKFC_00485	3.44e-200	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HEKEIKFC_00486	2.51e-259	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_00487	7.01e-213	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HEKEIKFC_00488	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEKEIKFC_00489	8.94e-119	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HEKEIKFC_00490	6.54e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEKEIKFC_00491	3.3e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HEKEIKFC_00494	7.42e-112	yxjI	-	-	S	-	-	-	LURP-one-related
HEKEIKFC_00495	2.8e-278	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HEKEIKFC_00496	9.15e-207	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HEKEIKFC_00497	2.85e-267	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEKEIKFC_00498	1.25e-124	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HEKEIKFC_00499	2.38e-65	yxiS	-	-	-	-	-	-	-
HEKEIKFC_00501	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEKEIKFC_00502	1.57e-281	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HEKEIKFC_00503	2.33e-184	bglS	-	-	M	-	-	-	licheninase activity
HEKEIKFC_00504	3.41e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HEKEIKFC_00505	1.82e-282	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HEKEIKFC_00506	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEKEIKFC_00508	4.6e-28	-	-	-	-	-	-	-	-
HEKEIKFC_00510	9.96e-134	-	-	-	-	-	-	-	-
HEKEIKFC_00514	2.09e-91	yxiG	-	-	-	-	-	-	-
HEKEIKFC_00515	4.19e-87	yxxG	-	-	-	-	-	-	-
HEKEIKFC_00522	5.15e-67	-	-	-	-	-	-	-	-
HEKEIKFC_00523	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HEKEIKFC_00524	9.42e-258	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HEKEIKFC_00525	5.94e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HEKEIKFC_00526	1.26e-96	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEKEIKFC_00527	1.04e-196	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEKEIKFC_00528	0.0	-	-	-	L	-	-	-	HKD family nuclease
HEKEIKFC_00529	5.87e-86	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEKEIKFC_00530	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HEKEIKFC_00531	9.97e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HEKEIKFC_00532	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HEKEIKFC_00533	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEKEIKFC_00534	1.24e-296	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HEKEIKFC_00535	2.04e-226	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HEKEIKFC_00536	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEKEIKFC_00537	1.57e-296	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HEKEIKFC_00538	4.04e-265	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEKEIKFC_00539	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEKEIKFC_00540	2.36e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEKEIKFC_00541	1.91e-192	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HEKEIKFC_00544	3.81e-33	yxeE	-	-	-	-	-	-	-
HEKEIKFC_00545	5.09e-35	yxeD	-	-	-	-	-	-	-
HEKEIKFC_00546	4.62e-45	-	-	-	-	-	-	-	-
HEKEIKFC_00547	1.75e-229	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEKEIKFC_00548	4.9e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HEKEIKFC_00549	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEKEIKFC_00550	1.89e-181	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_00551	6.53e-223	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_00552	9.37e-159	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_00553	0.0	-	-	-	T	-	-	-	Histidine kinase
HEKEIKFC_00554	1.57e-176	yvrH	-	-	T	-	-	-	Transcriptional regulator
HEKEIKFC_00555	5.31e-211	-	-	-	V	ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_00556	1.36e-167	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	permease
HEKEIKFC_00557	1.89e-170	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_00558	3.3e-203	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HEKEIKFC_00559	1.03e-201	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HEKEIKFC_00560	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HEKEIKFC_00561	5.4e-252	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEKEIKFC_00562	1.82e-294	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HEKEIKFC_00563	3.96e-224	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEKEIKFC_00564	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HEKEIKFC_00565	6.88e-232	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEKEIKFC_00566	6.21e-203	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HEKEIKFC_00567	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEKEIKFC_00568	6.09e-175	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEKEIKFC_00569	1.43e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HEKEIKFC_00570	5.16e-88	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HEKEIKFC_00571	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HEKEIKFC_00572	2.91e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEKEIKFC_00573	6.58e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HEKEIKFC_00574	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEKEIKFC_00575	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HEKEIKFC_00576	5.18e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEKEIKFC_00577	2.73e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEKEIKFC_00578	2.9e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HEKEIKFC_00579	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEKEIKFC_00580	1.05e-69	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HEKEIKFC_00581	2.6e-279	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HEKEIKFC_00582	2.51e-260	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEKEIKFC_00583	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HEKEIKFC_00584	3.84e-234	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HEKEIKFC_00585	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HEKEIKFC_00586	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HEKEIKFC_00587	3.42e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HEKEIKFC_00588	8.04e-191	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEKEIKFC_00589	8.39e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HEKEIKFC_00590	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEKEIKFC_00591	2.38e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HEKEIKFC_00592	2.89e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEKEIKFC_00593	3.12e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HEKEIKFC_00594	2.32e-198	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEKEIKFC_00595	7.93e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEKEIKFC_00596	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HEKEIKFC_00598	3.07e-179	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HEKEIKFC_00599	8.09e-181	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HEKEIKFC_00600	8.36e-138	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HEKEIKFC_00601	4.51e-47	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HEKEIKFC_00602	1.82e-276	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HEKEIKFC_00603	5.58e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEKEIKFC_00604	6.2e-203	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HEKEIKFC_00605	1.63e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HEKEIKFC_00606	1.84e-91	psiE	-	-	S	ko:K13256	-	ko00000	Belongs to the PsiE family
HEKEIKFC_00607	1.58e-300	yrkQ	-	-	T	-	-	-	Histidine kinase
HEKEIKFC_00608	1.33e-159	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
HEKEIKFC_00609	3.14e-275	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HEKEIKFC_00610	1.56e-130	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HEKEIKFC_00611	2.23e-129	yqaC	-	-	F	-	-	-	adenylate kinase activity
HEKEIKFC_00612	5.25e-41	-	-	-	K	-	-	-	acetyltransferase
HEKEIKFC_00613	1.87e-280	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_00614	2.89e-103	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HEKEIKFC_00615	4.07e-122	-	-	-	S	-	-	-	DinB family
HEKEIKFC_00616	4.85e-189	supH	-	-	S	-	-	-	hydrolase
HEKEIKFC_00617	3.96e-185	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HEKEIKFC_00618	1.68e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HEKEIKFC_00619	1.46e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEKEIKFC_00620	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_00621	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HEKEIKFC_00622	4.86e-233	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
HEKEIKFC_00623	7.97e-108	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEKEIKFC_00624	4.38e-210	yybE	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00625	2.18e-269	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_00626	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HEKEIKFC_00627	4.77e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HEKEIKFC_00628	2.12e-119	yrhH	-	-	Q	-	-	-	methyltransferase
HEKEIKFC_00629	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HEKEIKFC_00630	3.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HEKEIKFC_00631	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HEKEIKFC_00632	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HEKEIKFC_00633	3.91e-105	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEKEIKFC_00634	9.51e-47	yrhC	-	-	S	-	-	-	YrhC-like protein
HEKEIKFC_00635	7.59e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEKEIKFC_00636	1.61e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HEKEIKFC_00637	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEKEIKFC_00638	1.35e-150	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HEKEIKFC_00639	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HEKEIKFC_00640	3.56e-124	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HEKEIKFC_00641	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HEKEIKFC_00642	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEKEIKFC_00643	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HEKEIKFC_00644	1.88e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HEKEIKFC_00645	2.2e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HEKEIKFC_00646	2.22e-151	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HEKEIKFC_00647	8.08e-259	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEKEIKFC_00648	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HEKEIKFC_00649	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEKEIKFC_00650	1.29e-54	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HEKEIKFC_00651	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEKEIKFC_00652	4.67e-237	yrrI	-	-	S	-	-	-	AI-2E family transporter
HEKEIKFC_00653	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEKEIKFC_00654	4.27e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEKEIKFC_00655	3.94e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEKEIKFC_00656	1.54e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEKEIKFC_00657	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HEKEIKFC_00658	8.4e-42	yrzR	-	-	-	-	-	-	-
HEKEIKFC_00659	1.76e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_00660	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEKEIKFC_00661	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEKEIKFC_00662	3.55e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEKEIKFC_00663	2.1e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEKEIKFC_00664	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_00665	9.19e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HEKEIKFC_00666	2.39e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEKEIKFC_00667	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEKEIKFC_00668	6.05e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HEKEIKFC_00671	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HEKEIKFC_00672	2.86e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEKEIKFC_00673	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEKEIKFC_00674	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEKEIKFC_00675	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HEKEIKFC_00676	2.14e-60	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HEKEIKFC_00677	2.18e-112	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HEKEIKFC_00678	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEKEIKFC_00679	4.04e-67	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HEKEIKFC_00680	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEKEIKFC_00681	2.03e-143	yrbG	-	-	S	-	-	-	membrane
HEKEIKFC_00682	3.7e-80	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HEKEIKFC_00683	1.03e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HEKEIKFC_00684	8.2e-293	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEKEIKFC_00685	5.79e-246	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEKEIKFC_00686	6.87e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HEKEIKFC_00687	3.57e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEKEIKFC_00688	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEKEIKFC_00689	1.03e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HEKEIKFC_00691	1.91e-62	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEKEIKFC_00692	1.48e-247	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HEKEIKFC_00693	5.79e-270	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEKEIKFC_00694	4.31e-195	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HEKEIKFC_00695	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HEKEIKFC_00696	1.06e-280	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEKEIKFC_00697	1.38e-120	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HEKEIKFC_00698	8.16e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HEKEIKFC_00699	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HEKEIKFC_00700	2.37e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEKEIKFC_00701	3.5e-138	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HEKEIKFC_00702	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HEKEIKFC_00703	1.42e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HEKEIKFC_00704	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HEKEIKFC_00705	5.1e-206	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HEKEIKFC_00706	1.39e-188	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HEKEIKFC_00707	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HEKEIKFC_00708	6.85e-155	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEKEIKFC_00709	1.76e-110	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HEKEIKFC_00710	2.51e-201	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HEKEIKFC_00711	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HEKEIKFC_00712	8.76e-131	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEKEIKFC_00713	6.56e-52	-	-	-	-	-	-	-	-
HEKEIKFC_00714	3.52e-83	-	-	-	-	-	-	-	-
HEKEIKFC_00715	1.42e-84	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEKEIKFC_00716	2.82e-33	xhlB	-	-	S	-	-	-	SPP1 phage holin
HEKEIKFC_00717	4.67e-29	bhlA	-	-	S	-	-	-	BhlA holin family
HEKEIKFC_00720	2.04e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEKEIKFC_00721	4.06e-130	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEKEIKFC_00722	1.22e-110	-	-	-	S	-	-	-	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
HEKEIKFC_00723	1.74e-14	-	-	-	M	-	-	-	Prophage endopeptidase tail
HEKEIKFC_00724	4.3e-21	-	-	-	S	-	-	-	Phage tail protein
HEKEIKFC_00725	7.45e-65	-	-	-	S	-	-	-	Phage-related minor tail protein
HEKEIKFC_00732	1.04e-146	-	-	-	S	-	-	-	Phage capsid family
HEKEIKFC_00733	7.72e-88	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HEKEIKFC_00734	5.47e-87	-	-	-	S	-	-	-	Phage portal protein
HEKEIKFC_00735	0.0	-	-	-	S	-	-	-	Terminase
HEKEIKFC_00736	1.25e-63	-	-	-	L	-	-	-	phage terminase small subunit
HEKEIKFC_00737	6.99e-42	-	-	-	V	-	-	-	HNH nucleases
HEKEIKFC_00739	4.37e-25	-	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00742	4.53e-79	-	-	-	-	-	-	-	-
HEKEIKFC_00744	9.18e-76	-	-	-	-	-	-	-	-
HEKEIKFC_00747	2.49e-105	-	-	-	-	-	-	-	-
HEKEIKFC_00748	3.98e-124	-	-	-	S	-	-	-	nuclease activity
HEKEIKFC_00750	3.89e-81	-	-	-	-	-	-	-	-
HEKEIKFC_00751	0.0	-	-	-	S	-	-	-	hydrolase activity
HEKEIKFC_00752	1.17e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HEKEIKFC_00753	5.58e-08	-	-	-	-	-	-	-	-
HEKEIKFC_00754	8.59e-221	-	-	-	S	-	-	-	AAA domain
HEKEIKFC_00755	2.77e-122	-	-	-	S	-	-	-	DNA protection
HEKEIKFC_00757	1.8e-32	-	-	-	S	-	-	-	Uncharacterized protein YqaH
HEKEIKFC_00760	1.15e-12	-	-	-	K	-	-	-	helix-turn-helix
HEKEIKFC_00761	1.43e-85	-	-	-	S	-	-	-	sequence-specific DNA binding
HEKEIKFC_00762	3.34e-101	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HEKEIKFC_00763	0.0	-	-	-	S	-	-	-	Recombinase
HEKEIKFC_00764	8.68e-90	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HEKEIKFC_00765	1.53e-126	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HEKEIKFC_00766	1.27e-208	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HEKEIKFC_00767	1.81e-171	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HEKEIKFC_00768	3.62e-305	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HEKEIKFC_00769	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEKEIKFC_00770	1.53e-35	-	-	-	-	-	-	-	-
HEKEIKFC_00771	1.81e-249	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEKEIKFC_00772	5.36e-303	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HEKEIKFC_00773	1.62e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HEKEIKFC_00774	1.4e-235	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HEKEIKFC_00775	1.62e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HEKEIKFC_00776	5.19e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEKEIKFC_00777	1.88e-186	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HEKEIKFC_00778	4.36e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEKEIKFC_00779	6.8e-115	ysxD	-	-	-	-	-	-	-
HEKEIKFC_00780	1.79e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HEKEIKFC_00781	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEKEIKFC_00782	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HEKEIKFC_00783	5.44e-295	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEKEIKFC_00784	2.18e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEKEIKFC_00785	9.14e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HEKEIKFC_00786	3.77e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEKEIKFC_00787	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEKEIKFC_00788	1.75e-254	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEKEIKFC_00789	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEKEIKFC_00790	2.75e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEKEIKFC_00791	2.06e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HEKEIKFC_00792	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HEKEIKFC_00795	6.58e-162	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HEKEIKFC_00796	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
HEKEIKFC_00797	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HEKEIKFC_00801	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HEKEIKFC_00802	1.59e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEKEIKFC_00803	1.44e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEKEIKFC_00804	4.47e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HEKEIKFC_00805	4.68e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HEKEIKFC_00806	3.77e-97	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEKEIKFC_00807	1.6e-200	-	-	-	L	-	-	-	Recombinase
HEKEIKFC_00808	3.77e-09	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEKEIKFC_00810	2.78e-22	-	-	-	-	-	-	-	-
HEKEIKFC_00812	1.16e-232	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HEKEIKFC_00815	1.94e-28	-	-	-	K	-	-	-	Helix-turn-helix domain
HEKEIKFC_00817	4.4e-07	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HEKEIKFC_00818	1.58e-86	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEKEIKFC_00819	2.95e-37	xhlB	-	-	S	-	-	-	SPP1 phage holin
HEKEIKFC_00820	1.19e-40	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HEKEIKFC_00821	1.64e-24	xkdX	-	-	-	-	-	-	-
HEKEIKFC_00823	4.93e-71	-	-	-	-	-	-	-	-
HEKEIKFC_00824	5.24e-80	-	-	-	-	-	-	-	-
HEKEIKFC_00825	3.19e-126	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
HEKEIKFC_00826	3.5e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HEKEIKFC_00827	6.47e-35	-	-	-	-	-	-	-	-
HEKEIKFC_00828	1.25e-109	-	-	-	-	-	-	-	-
HEKEIKFC_00829	5.45e-31	-	-	-	-	-	-	-	-
HEKEIKFC_00830	4.7e-55	-	-	-	M	-	-	-	LysM domain
HEKEIKFC_00831	7.34e-180	-	-	-	N	-	-	-	phage tail tape measure protein
HEKEIKFC_00832	5.77e-19	-	-	-	-	-	-	-	-
HEKEIKFC_00833	9.14e-46	-	-	-	-	-	-	-	-
HEKEIKFC_00834	1.78e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
HEKEIKFC_00835	7.33e-42	-	-	-	-	-	-	-	-
HEKEIKFC_00837	6.98e-61	-	-	-	-	-	-	-	-
HEKEIKFC_00839	1.88e-39	-	-	-	S	-	-	-	Phage Mu protein F like protein
HEKEIKFC_00841	2.29e-156	-	-	-	S	-	-	-	P22 coat protein - gene protein 5
HEKEIKFC_00842	2.44e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HEKEIKFC_00843	1.38e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HEKEIKFC_00845	2.7e-193	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HEKEIKFC_00846	3.49e-233	-	-	-	S	-	-	-	Terminase-like family
HEKEIKFC_00847	2.62e-103	yqaS	-	-	L	-	-	-	DNA packaging
HEKEIKFC_00849	9.97e-62	-	-	-	L	-	-	-	Transposase
HEKEIKFC_00853	5.15e-60	-	-	-	-	-	-	-	-
HEKEIKFC_00868	3.04e-73	-	-	-	-	-	-	-	-
HEKEIKFC_00871	1.77e-84	-	-	-	-	-	-	-	-
HEKEIKFC_00874	1.16e-23	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HEKEIKFC_00876	4.29e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HEKEIKFC_00877	5.02e-09	-	-	-	-	-	-	-	-
HEKEIKFC_00879	6.95e-71	-	-	-	L	ko:K02315	-	ko00000,ko03032	Bacterial dnaA protein
HEKEIKFC_00881	4.05e-140	recT	-	-	L	ko:K07455	-	ko00000,ko03400	Recombinational DNA repair protein (RecE pathway)
HEKEIKFC_00882	2.15e-139	-	-	-	S	-	-	-	YqaJ-like viral recombinase domain
HEKEIKFC_00887	1.06e-99	-	-	-	-	-	-	-	-
HEKEIKFC_00888	3.26e-39	-	-	-	S	-	-	-	DNA binding
HEKEIKFC_00890	5.96e-23	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEKEIKFC_00891	9.25e-32	-	-	-	K	ko:K07467	-	ko00000	sequence-specific DNA binding
HEKEIKFC_00892	1e-06	-	-	-	-	-	-	-	-
HEKEIKFC_00893	3.4e-35	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HEKEIKFC_00894	4.14e-25	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_00895	2.19e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HEKEIKFC_00896	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HEKEIKFC_00897	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HEKEIKFC_00898	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HEKEIKFC_00899	2.45e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HEKEIKFC_00900	1.23e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEKEIKFC_00901	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEKEIKFC_00902	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HEKEIKFC_00903	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HEKEIKFC_00904	1.43e-226	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HEKEIKFC_00905	1.01e-176	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HEKEIKFC_00906	7.09e-178	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HEKEIKFC_00907	1.78e-133	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_00908	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEKEIKFC_00909	8.1e-103	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HEKEIKFC_00910	9.2e-32	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HEKEIKFC_00911	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HEKEIKFC_00912	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEKEIKFC_00913	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HEKEIKFC_00914	3.5e-108	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HEKEIKFC_00915	3.48e-53	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEKEIKFC_00916	8.83e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEKEIKFC_00917	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEKEIKFC_00918	2.19e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEKEIKFC_00919	3.65e-170	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEKEIKFC_00920	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HEKEIKFC_00921	1.02e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HEKEIKFC_00922	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
HEKEIKFC_00923	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HEKEIKFC_00924	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HEKEIKFC_00925	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HEKEIKFC_00926	1.18e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HEKEIKFC_00927	1.78e-214	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HEKEIKFC_00928	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HEKEIKFC_00929	2.34e-285	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HEKEIKFC_00930	1.7e-178	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HEKEIKFC_00931	3.43e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HEKEIKFC_00932	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HEKEIKFC_00933	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HEKEIKFC_00934	2.84e-240	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HEKEIKFC_00935	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HEKEIKFC_00936	3.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HEKEIKFC_00937	5.25e-54	ysdA	-	-	S	-	-	-	Membrane
HEKEIKFC_00938	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEKEIKFC_00939	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HEKEIKFC_00940	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEKEIKFC_00941	2.09e-145	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEKEIKFC_00942	7.85e-67	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
HEKEIKFC_00943	4.27e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HEKEIKFC_00944	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_00945	2.82e-191	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HEKEIKFC_00946	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEKEIKFC_00947	1.63e-196	ytxC	-	-	S	-	-	-	YtxC-like family
HEKEIKFC_00948	4.27e-138	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HEKEIKFC_00949	2.87e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HEKEIKFC_00950	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HEKEIKFC_00951	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEKEIKFC_00952	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HEKEIKFC_00953	1.73e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEKEIKFC_00954	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_00955	1.61e-258	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HEKEIKFC_00956	3.74e-204	ytbE	-	-	S	-	-	-	reductase
HEKEIKFC_00957	4.17e-128	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEKEIKFC_00958	5.73e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEKEIKFC_00959	1.35e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEKEIKFC_00960	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEKEIKFC_00961	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HEKEIKFC_00962	1.38e-165	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_00963	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HEKEIKFC_00964	1.32e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HEKEIKFC_00965	2.02e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEKEIKFC_00966	1.58e-82	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HEKEIKFC_00967	2.3e-95	ytwI	-	-	S	-	-	-	membrane
HEKEIKFC_00968	4.05e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HEKEIKFC_00969	3.42e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HEKEIKFC_00970	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HEKEIKFC_00971	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEKEIKFC_00972	1.15e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEKEIKFC_00973	3.59e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEKEIKFC_00974	1.72e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HEKEIKFC_00975	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HEKEIKFC_00976	4.94e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HEKEIKFC_00977	2.64e-114	ytrI	-	-	-	-	-	-	-
HEKEIKFC_00978	1e-31	-	-	-	-	-	-	-	-
HEKEIKFC_00979	2.14e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HEKEIKFC_00980	3.05e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
HEKEIKFC_00981	6.77e-305	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HEKEIKFC_00982	4.86e-165	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HEKEIKFC_00983	3.41e-183	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_00985	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HEKEIKFC_00986	3.03e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEKEIKFC_00987	4.03e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HEKEIKFC_00988	3.3e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEKEIKFC_00989	3.18e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HEKEIKFC_00990	1.36e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEKEIKFC_00991	4.77e-100	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HEKEIKFC_00992	3.66e-156	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HEKEIKFC_00993	2.77e-114	yteJ	-	-	S	-	-	-	RDD family
HEKEIKFC_00994	5.25e-234	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HEKEIKFC_00995	1.91e-195	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEKEIKFC_00996	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HEKEIKFC_00997	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEKEIKFC_00998	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HEKEIKFC_00999	2.44e-286	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEKEIKFC_01000	1.85e-264	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEKEIKFC_01001	1.32e-306	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HEKEIKFC_01002	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEKEIKFC_01003	4.18e-196	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HEKEIKFC_01004	2.41e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_01005	2.48e-111	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HEKEIKFC_01006	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HEKEIKFC_01007	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEKEIKFC_01008	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEKEIKFC_01009	1.81e-132	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HEKEIKFC_01010	4.14e-60	-	-	-	D	-	-	-	nuclear chromosome segregation
HEKEIKFC_01013	7.73e-61	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HEKEIKFC_01014	7.33e-24	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEKEIKFC_01015	5.58e-21	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEKEIKFC_01017	1.85e-283	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEKEIKFC_01019	1.65e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HEKEIKFC_01021	2.49e-178	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEKEIKFC_01022	1.74e-193	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEKEIKFC_01023	7.76e-191	-	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_01024	5.77e-160	ygaZ	-	-	E	-	-	-	AzlC protein
HEKEIKFC_01025	3.06e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HEKEIKFC_01026	5.98e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEKEIKFC_01027	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEKEIKFC_01028	1.71e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HEKEIKFC_01029	7.2e-151	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HEKEIKFC_01030	1.17e-291	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HEKEIKFC_01031	1.05e-155	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HEKEIKFC_01032	5.2e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HEKEIKFC_01033	2.06e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HEKEIKFC_01034	6.28e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HEKEIKFC_01035	8.39e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HEKEIKFC_01036	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HEKEIKFC_01037	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEKEIKFC_01038	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HEKEIKFC_01039	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEKEIKFC_01040	2.43e-138	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEKEIKFC_01041	1.69e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HEKEIKFC_01042	1.57e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HEKEIKFC_01043	1.42e-102	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HEKEIKFC_01044	5.06e-259	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HEKEIKFC_01045	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
HEKEIKFC_01046	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HEKEIKFC_01047	7.89e-211	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEKEIKFC_01048	6.43e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEKEIKFC_01049	3.88e-60	ytzH	-	-	S	-	-	-	YtzH-like protein
HEKEIKFC_01050	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
HEKEIKFC_01051	8.33e-227	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HEKEIKFC_01052	2.85e-214	ytlQ	-	-	-	-	-	-	-
HEKEIKFC_01053	1.1e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEKEIKFC_01054	4.79e-222	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEKEIKFC_01055	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HEKEIKFC_01056	2.99e-290	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEKEIKFC_01057	1.5e-277	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HEKEIKFC_01058	2.58e-163	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEKEIKFC_01059	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HEKEIKFC_01060	1.01e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEKEIKFC_01061	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEKEIKFC_01062	3.73e-299	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HEKEIKFC_01063	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HEKEIKFC_01064	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HEKEIKFC_01065	3.87e-239	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_01066	6.55e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HEKEIKFC_01067	2.54e-214	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEKEIKFC_01068	2.88e-184	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEKEIKFC_01069	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HEKEIKFC_01070	1.69e-111	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HEKEIKFC_01071	6.05e-69	ytwF	-	-	P	-	-	-	Sulfurtransferase
HEKEIKFC_01072	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HEKEIKFC_01073	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HEKEIKFC_01074	1.77e-176	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HEKEIKFC_01075	2.46e-271	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HEKEIKFC_01076	1.08e-159	ywaF	-	-	S	-	-	-	Integral membrane protein
HEKEIKFC_01077	3.21e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEKEIKFC_01078	1.02e-103	yjoA	-	-	S	-	-	-	DinB family
HEKEIKFC_01079	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEKEIKFC_01081	2.37e-221	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEKEIKFC_01082	9.51e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
HEKEIKFC_01083	8.47e-141	yjqB	-	-	S	-	-	-	phage-related replication protein
HEKEIKFC_01084	7.99e-189	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
HEKEIKFC_01085	1.87e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HEKEIKFC_01086	6.52e-75	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEKEIKFC_01088	1.85e-197	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HEKEIKFC_01092	1.07e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEKEIKFC_01093	6.81e-140	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HEKEIKFC_01094	3.9e-262	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HEKEIKFC_01095	8.55e-303	xkdE3	-	-	S	-	-	-	portal protein
HEKEIKFC_01096	8.8e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HEKEIKFC_01097	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
HEKEIKFC_01098	2.17e-61	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HEKEIKFC_01099	1.66e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HEKEIKFC_01100	1.2e-77	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEKEIKFC_01101	4.28e-74	xkdJ	-	-	-	-	-	-	-
HEKEIKFC_01102	1.57e-20	-	-	-	-	-	-	-	-
HEKEIKFC_01103	2.31e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HEKEIKFC_01104	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
HEKEIKFC_01105	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HEKEIKFC_01106	4.33e-27	-	-	-	-	-	-	-	-
HEKEIKFC_01107	2.04e-284	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HEKEIKFC_01108	1.88e-144	xkdP	-	-	S	-	-	-	Lysin motif
HEKEIKFC_01109	1.87e-206	xkdQ	-	-	G	-	-	-	NLP P60 protein
HEKEIKFC_01110	2.51e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HEKEIKFC_01111	2.86e-76	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HEKEIKFC_01112	5.34e-213	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HEKEIKFC_01113	2.48e-113	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HEKEIKFC_01114	7.33e-37	-	-	-	-	-	-	-	-
HEKEIKFC_01115	2.43e-229	-	-	-	-	-	-	-	-
HEKEIKFC_01117	5.6e-41	xkdX	-	-	-	-	-	-	-
HEKEIKFC_01118	6.59e-145	xepA	-	-	-	-	-	-	-
HEKEIKFC_01119	1.11e-50	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HEKEIKFC_01120	4.7e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
HEKEIKFC_01121	5.16e-217	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEKEIKFC_01122	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HEKEIKFC_01123	1.89e-172	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HEKEIKFC_01124	7.07e-226	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HEKEIKFC_01125	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HEKEIKFC_01126	2.3e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HEKEIKFC_01127	2.31e-232	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEKEIKFC_01128	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEKEIKFC_01129	1.56e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEKEIKFC_01131	1.59e-277	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEKEIKFC_01132	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HEKEIKFC_01134	4.36e-200	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HEKEIKFC_01135	1.14e-203	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKEIKFC_01136	6.59e-227	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKEIKFC_01137	3.91e-244	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_01138	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEKEIKFC_01139	1.14e-225	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HEKEIKFC_01140	1.06e-255	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HEKEIKFC_01141	3.94e-220	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEKEIKFC_01142	2.31e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_01143	1.46e-263	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HEKEIKFC_01144	1.71e-203	ykgA	-	-	E	-	-	-	Amidinotransferase
HEKEIKFC_01145	8.79e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HEKEIKFC_01146	1.34e-132	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEKEIKFC_01147	4.09e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HEKEIKFC_01148	1.04e-65	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HEKEIKFC_01149	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HEKEIKFC_01150	7.52e-263	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEKEIKFC_01151	7.94e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEKEIKFC_01152	6.87e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HEKEIKFC_01153	2.43e-111	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HEKEIKFC_01154	1.58e-91	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HEKEIKFC_01155	3.86e-81	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEKEIKFC_01157	6.09e-276	-	-	-	M	-	-	-	Glycosyl transferase family 2
HEKEIKFC_01158	9.54e-186	-	-	-	M	-	-	-	PFAM Collagen triple helix repeat (20 copies)
HEKEIKFC_01159	1.39e-277	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_01160	2.61e-154	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HEKEIKFC_01161	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEKEIKFC_01162	1.74e-224	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEKEIKFC_01163	1.1e-190	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEKEIKFC_01164	5.36e-170	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HEKEIKFC_01165	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_01166	2.31e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HEKEIKFC_01167	5.38e-311	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HEKEIKFC_01169	8.66e-310	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HEKEIKFC_01170	1.23e-69	tnrA	-	-	K	-	-	-	transcriptional
HEKEIKFC_01171	1.11e-23	-	-	-	-	-	-	-	-
HEKEIKFC_01172	5.25e-37	ykoL	-	-	-	-	-	-	-
HEKEIKFC_01173	5.46e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HEKEIKFC_01174	5.41e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HEKEIKFC_01175	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HEKEIKFC_01176	3.42e-202	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEKEIKFC_01177	1.17e-130	ykoX	-	-	S	-	-	-	membrane-associated protein
HEKEIKFC_01178	4.82e-172	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HEKEIKFC_01179	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEKEIKFC_01180	3.5e-241	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HEKEIKFC_01181	5.7e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HEKEIKFC_01182	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HEKEIKFC_01183	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HEKEIKFC_01184	3.8e-308	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HEKEIKFC_01185	6.05e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEKEIKFC_01186	3.07e-32	ykzE	-	-	-	-	-	-	-
HEKEIKFC_01187	3.9e-243	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HEKEIKFC_01188	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_01189	8.18e-112	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEKEIKFC_01191	1.81e-250	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HEKEIKFC_01192	6e-288	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HEKEIKFC_01193	6.67e-192	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEKEIKFC_01194	4.42e-292	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEKEIKFC_01195	2.73e-289	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HEKEIKFC_01196	2.71e-174	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HEKEIKFC_01197	1.24e-144	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HEKEIKFC_01198	2.6e-124	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HEKEIKFC_01200	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEKEIKFC_01201	1.36e-100	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HEKEIKFC_01202	4.04e-169	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HEKEIKFC_01203	7.27e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HEKEIKFC_01204	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HEKEIKFC_01205	2.69e-232	ykvI	-	-	S	-	-	-	membrane
HEKEIKFC_01206	6.86e-256	-	-	-	-	-	-	-	-
HEKEIKFC_01207	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEKEIKFC_01208	8.23e-106	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HEKEIKFC_01209	2.06e-178	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEKEIKFC_01210	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEKEIKFC_01211	1e-79	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HEKEIKFC_01212	1.81e-170	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEKEIKFC_01213	2.4e-27	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEKEIKFC_01214	0.0	-	-	-	S	-	-	-	AIPR protein
HEKEIKFC_01215	2.09e-59	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HEKEIKFC_01216	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_01217	4.16e-38	-	-	-	-	-	-	-	-
HEKEIKFC_01218	1.45e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HEKEIKFC_01219	2.66e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEKEIKFC_01220	2.1e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
HEKEIKFC_01221	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HEKEIKFC_01222	4.04e-264	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HEKEIKFC_01224	1.01e-224	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_01225	2.78e-199	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HEKEIKFC_01226	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_01227	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HEKEIKFC_01228	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEKEIKFC_01229	3.63e-50	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_01230	3.53e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HEKEIKFC_01231	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEKEIKFC_01232	1.15e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HEKEIKFC_01233	2.78e-160	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HEKEIKFC_01234	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEKEIKFC_01235	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_01236	4.65e-275	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEKEIKFC_01237	6.38e-15	-	-	-	-	-	-	-	-
HEKEIKFC_01238	1.93e-213	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HEKEIKFC_01239	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
HEKEIKFC_01240	7.96e-309	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_01241	8.88e-117	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_01242	6.6e-200	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HEKEIKFC_01243	3.54e-180	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_01245	7.72e-297	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HEKEIKFC_01246	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_01247	4.35e-120	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HEKEIKFC_01248	3.09e-35	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HEKEIKFC_01249	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
HEKEIKFC_01250	1.32e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_01251	3.15e-117	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEKEIKFC_01252	1.21e-213	ykuO	-	-	-	-	-	-	-
HEKEIKFC_01253	5.1e-102	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEKEIKFC_01254	2.89e-129	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEKEIKFC_01255	9.73e-277	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEKEIKFC_01256	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HEKEIKFC_01257	6.03e-179	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HEKEIKFC_01258	1.99e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
HEKEIKFC_01259	7.46e-127	rok	-	-	K	-	-	-	Repressor of ComK
HEKEIKFC_01260	2.53e-218	yknT	-	-	-	ko:K06437	-	ko00000	-
HEKEIKFC_01261	9.94e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEKEIKFC_01262	1.71e-241	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEKEIKFC_01263	5.6e-309	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HEKEIKFC_01264	2.64e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HEKEIKFC_01265	7.17e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HEKEIKFC_01266	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEKEIKFC_01267	4.64e-140	yknW	-	-	S	-	-	-	Yip1 domain
HEKEIKFC_01268	3.37e-238	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEKEIKFC_01269	2.9e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_01270	2.98e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HEKEIKFC_01271	6.81e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_01272	4.75e-214	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HEKEIKFC_01273	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HEKEIKFC_01274	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEKEIKFC_01275	5.23e-50	ykoA	-	-	-	-	-	-	-
HEKEIKFC_01276	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEKEIKFC_01277	1.53e-207	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEKEIKFC_01278	1.2e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEKEIKFC_01279	4.47e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HEKEIKFC_01280	3.72e-235	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HEKEIKFC_01281	6.37e-60	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HEKEIKFC_01282	2.39e-312	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEKEIKFC_01283	5.27e-197	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HEKEIKFC_01284	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HEKEIKFC_01285	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEKEIKFC_01286	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEKEIKFC_01287	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HEKEIKFC_01288	2.04e-184	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HEKEIKFC_01289	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEKEIKFC_01290	7.91e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEKEIKFC_01291	5.6e-134	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HEKEIKFC_01292	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEKEIKFC_01293	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_01294	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
HEKEIKFC_01295	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_01296	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_01297	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_01298	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_01299	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HEKEIKFC_01300	9.97e-269	-	-	-	V	-	-	-	Beta-lactamase
HEKEIKFC_01301	7.79e-261	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEKEIKFC_01302	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEKEIKFC_01303	2.96e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEKEIKFC_01304	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEKEIKFC_01305	7.97e-59	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HEKEIKFC_01306	5.69e-192	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HEKEIKFC_01307	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HEKEIKFC_01308	9.4e-57	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HEKEIKFC_01309	4.72e-154	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HEKEIKFC_01310	7.89e-32	ykzI	-	-	-	-	-	-	-
HEKEIKFC_01311	8.12e-196	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HEKEIKFC_01312	7.56e-108	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HEKEIKFC_01313	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HEKEIKFC_01314	3.93e-234	ylaA	-	-	-	-	-	-	-
HEKEIKFC_01315	7.37e-59	ylaB	-	-	-	-	-	-	-
HEKEIKFC_01316	4.7e-120	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEKEIKFC_01318	1.39e-52	ylaE	-	-	-	-	-	-	-
HEKEIKFC_01319	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HEKEIKFC_01320	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HEKEIKFC_01321	2.44e-65	-	-	-	S	-	-	-	YlaH-like protein
HEKEIKFC_01322	6.78e-46	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_01323	3.84e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEKEIKFC_01324	9.42e-314	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HEKEIKFC_01325	4.13e-109	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEKEIKFC_01326	7.73e-60	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEKEIKFC_01337	2.47e-14	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_01339	3.32e-29	-	-	-	K	-	-	-	Helix-turn-helix domain
HEKEIKFC_01341	2.74e-54	-	-	-	-	-	-	-	-
HEKEIKFC_01342	1.03e-31	-	-	-	-	-	-	-	-
HEKEIKFC_01343	1.32e-230	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HEKEIKFC_01344	1.37e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEKEIKFC_01346	2.15e-204	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEKEIKFC_01347	5.98e-27	-	-	-	-	-	-	-	-
HEKEIKFC_01349	1.55e-37	-	-	-	-	-	-	-	-
HEKEIKFC_01350	1.1e-296	-	-	-	S	-	-	-	Pfam Transposase IS66
HEKEIKFC_01351	1.3e-49	-	-	-	S	-	-	-	Phage tail protein
HEKEIKFC_01352	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HEKEIKFC_01353	2.62e-11	-	-	-	S	-	-	-	endonuclease activity
HEKEIKFC_01354	9.19e-28	-	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HEKEIKFC_01355	2.12e-122	-	-	-	T	-	-	-	Nacht domain
HEKEIKFC_01357	3.85e-66	-	-	-	-	-	-	-	-
HEKEIKFC_01358	4.64e-72	-	-	-	-	-	-	-	-
HEKEIKFC_01359	2.16e-14	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
HEKEIKFC_01361	1.8e-58	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEKEIKFC_01364	2.84e-227	-	-	-	-	-	-	-	-
HEKEIKFC_01366	3.93e-65	-	-	-	-	-	-	-	-
HEKEIKFC_01375	1.25e-86	-	-	-	L	ko:K06400	-	ko00000	Recombinase zinc beta ribbon domain
HEKEIKFC_01376	4.06e-155	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEKEIKFC_01377	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HEKEIKFC_01378	3.49e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEKEIKFC_01379	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEKEIKFC_01380	8.16e-213	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HEKEIKFC_01381	2.95e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEKEIKFC_01382	3.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEKEIKFC_01383	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEKEIKFC_01384	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HEKEIKFC_01385	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HEKEIKFC_01386	7.25e-212	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HEKEIKFC_01387	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEKEIKFC_01388	1.47e-144	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEKEIKFC_01389	3.32e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HEKEIKFC_01390	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
HEKEIKFC_01394	1.72e-83	yppG	-	-	S	-	-	-	YppG-like protein
HEKEIKFC_01395	5.09e-93	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEKEIKFC_01396	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HEKEIKFC_01397	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HEKEIKFC_01398	1.83e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HEKEIKFC_01399	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HEKEIKFC_01400	1.33e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HEKEIKFC_01401	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEKEIKFC_01402	4.68e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HEKEIKFC_01403	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
HEKEIKFC_01405	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HEKEIKFC_01406	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEKEIKFC_01407	8.16e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEKEIKFC_01408	5.71e-79	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HEKEIKFC_01409	6.97e-47	-	-	-	L	-	-	-	Recombinase
HEKEIKFC_01410	8.99e-110	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HEKEIKFC_01411	7.74e-121	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HEKEIKFC_01412	1.66e-211	-	-	-	V	-	-	-	HNH endonuclease
HEKEIKFC_01413	9.97e-273	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEKEIKFC_01414	1.22e-126	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HEKEIKFC_01416	7.56e-165	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HEKEIKFC_01417	1.27e-53	-	-	-	S	-	-	-	YolD-like protein
HEKEIKFC_01418	3.21e-285	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEKEIKFC_01420	1.94e-122	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEKEIKFC_01421	5e-06	-	-	-	-	-	-	-	-
HEKEIKFC_01423	1.83e-45	-	-	-	S	-	-	-	Bacteriophage holin
HEKEIKFC_01425	3.33e-97	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEKEIKFC_01426	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
HEKEIKFC_01427	1.17e-156	-	-	-	-	-	-	-	-
HEKEIKFC_01428	0.0	-	-	-	S	-	-	-	Pfam Transposase IS66
HEKEIKFC_01429	2.42e-161	-	-	-	S	-	-	-	Phage tail protein
HEKEIKFC_01430	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HEKEIKFC_01431	2.36e-75	-	-	-	-	-	-	-	-
HEKEIKFC_01433	2.15e-50	-	-	-	-	-	-	-	-
HEKEIKFC_01434	3.53e-82	-	-	-	S	-	-	-	DNA integration
HEKEIKFC_01435	4.48e-65	-	-	-	-	-	-	-	-
HEKEIKFC_01436	1.26e-76	-	-	-	-	-	-	-	-
HEKEIKFC_01437	1.28e-103	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
HEKEIKFC_01439	1.5e-27	-	-	-	-	-	-	-	-
HEKEIKFC_01440	4.29e-65	-	-	-	-	-	-	-	-
HEKEIKFC_01442	1.42e-73	-	-	-	-	-	-	-	-
HEKEIKFC_01443	9.4e-149	-	-	-	-	-	-	-	-
HEKEIKFC_01444	1.21e-110	-	-	-	-	-	-	-	-
HEKEIKFC_01445	5.89e-70	-	-	-	-	-	-	-	-
HEKEIKFC_01448	8.56e-85	-	-	-	-	-	-	-	-
HEKEIKFC_01452	1.1e-130	-	-	-	-	-	-	-	-
HEKEIKFC_01457	6.29e-291	-	-	-	S	-	-	-	hydrolase activity
HEKEIKFC_01461	6.78e-47	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEKEIKFC_01462	0.0	-	-	-	-	-	-	-	-
HEKEIKFC_01466	1.94e-73	-	-	-	D	-	-	-	Tubulin/FtsZ family, GTPase domain
HEKEIKFC_01467	6.07e-39	-	-	-	D	-	-	-	nuclear chromosome segregation
HEKEIKFC_01470	1.23e-275	-	-	-	-	-	-	-	-
HEKEIKFC_01471	4.19e-05	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HEKEIKFC_01472	1.31e-248	-	-	-	L	-	-	-	Domain of unknown function (DUF4942)
HEKEIKFC_01478	0.000613	-	-	-	I	-	-	-	Acyltransferase family
HEKEIKFC_01480	5.36e-92	yoaW	-	-	-	-	-	-	-
HEKEIKFC_01481	6.23e-13	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HEKEIKFC_01488	2.02e-34	-	-	-	-	-	-	-	-
HEKEIKFC_01490	1.68e-41	yoaF	-	-	-	-	-	-	-
HEKEIKFC_01492	1.2e-84	-	-	-	-	-	-	-	-
HEKEIKFC_01499	2.69e-238	-	-	-	-	-	-	-	-
HEKEIKFC_01500	2.41e-31	-	-	-	-	-	-	-	-
HEKEIKFC_01501	9.24e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_01505	4.53e-55	-	-	-	-	-	-	-	-
HEKEIKFC_01506	0.000188	-	-	-	S	-	-	-	YopX protein
HEKEIKFC_01518	1.86e-94	-	-	-	-	-	-	-	-
HEKEIKFC_01520	1.51e-70	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
HEKEIKFC_01523	1.63e-93	-	-	-	-	-	-	-	-
HEKEIKFC_01525	6.73e-177	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
HEKEIKFC_01526	2.32e-161	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HEKEIKFC_01528	1.99e-31	-	-	-	S	-	-	-	YopX protein
HEKEIKFC_01530	5.52e-118	-	-	-	S	-	-	-	Pfam:DUF867
HEKEIKFC_01531	5.65e-275	-	-	-	M	-	-	-	Parallel beta-helix repeats
HEKEIKFC_01535	9.76e-203	-	-	-	-	-	-	-	-
HEKEIKFC_01536	1.71e-217	-	-	-	L	-	-	-	AAA domain
HEKEIKFC_01537	3.83e-104	-	-	-	-	-	-	-	-
HEKEIKFC_01538	0.0	-	-	-	J	-	-	-	DnaB-like helicase C terminal domain
HEKEIKFC_01539	3.45e-263	-	-	-	L	-	-	-	DNA primase activity
HEKEIKFC_01540	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HEKEIKFC_01541	0.0	-	-	-	S	-	-	-	Bacterial DNA polymerase III alpha subunit
HEKEIKFC_01542	3.08e-31	-	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_01545	6.82e-91	tmk	2.1.1.45, 2.7.4.9	-	F	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dTDP biosynthetic process
HEKEIKFC_01546	2.01e-106	-	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl synthetase-associated domain
HEKEIKFC_01547	7.43e-264	-	2.4.2.12	-	H	ko:K03462	ko00760,ko01100,ko04621,map00760,map01100,map04621	ko00000,ko00001,ko01000	Nicotinate phosphoribosyltransferase (NAPRTase) family
HEKEIKFC_01548	6.88e-106	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HEKEIKFC_01552	1.28e-17	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HEKEIKFC_01554	3.06e-26	-	-	-	-	-	-	-	-
HEKEIKFC_01559	3.23e-75	-	-	-	S	-	-	-	NrdI Flavodoxin like
HEKEIKFC_01560	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEKEIKFC_01562	3.89e-212	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEKEIKFC_01563	2.78e-37	-	-	-	O	-	-	-	Glutaredoxin
HEKEIKFC_01566	1.8e-72	ymaB	-	-	S	-	-	-	MutT family
HEKEIKFC_01570	2.69e-192	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEKEIKFC_01571	1.47e-35	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEKEIKFC_01575	9.54e-22	-	-	-	-	-	-	-	-
HEKEIKFC_01577	8.52e-06	-	-	-	-	-	-	-	-
HEKEIKFC_01579	2.43e-114	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEKEIKFC_01581	5.09e-202	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HEKEIKFC_01582	2.23e-07	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HEKEIKFC_01583	3.64e-129	yrdC	-	-	Q	-	-	-	Isochorismatase family
HEKEIKFC_01584	5.38e-44	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEKEIKFC_01585	3.74e-44	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEKEIKFC_01586	1.21e-08	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HEKEIKFC_01587	2.21e-66	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
HEKEIKFC_01588	1.07e-137	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEKEIKFC_01589	1.53e-269	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HEKEIKFC_01590	1.47e-116	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HEKEIKFC_01591	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HEKEIKFC_01592	8.23e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HEKEIKFC_01593	2.44e-10	-	-	-	-	-	-	-	-
HEKEIKFC_01594	3.33e-210	ypcP	-	-	L	-	-	-	5'3' exonuclease
HEKEIKFC_01596	2.11e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HEKEIKFC_01597	2.68e-152	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEKEIKFC_01598	1.69e-158	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HEKEIKFC_01599	6.59e-40	ypeQ	-	-	S	-	-	-	Zinc-finger
HEKEIKFC_01600	3.78e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HEKEIKFC_01601	5.19e-17	degR	-	-	-	-	-	-	-
HEKEIKFC_01602	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HEKEIKFC_01603	9e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HEKEIKFC_01604	9.38e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEKEIKFC_01605	6.26e-110	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HEKEIKFC_01606	5.63e-129	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HEKEIKFC_01607	3.51e-200	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HEKEIKFC_01608	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HEKEIKFC_01609	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HEKEIKFC_01610	2.46e-172	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HEKEIKFC_01611	2.17e-146	ypjP	-	-	S	-	-	-	YpjP-like protein
HEKEIKFC_01612	6.22e-204	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEKEIKFC_01613	5.2e-118	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEKEIKFC_01614	1.92e-147	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEKEIKFC_01615	5.24e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HEKEIKFC_01616	6.48e-221	yplP	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_01617	8.57e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEKEIKFC_01618	7.13e-52	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HEKEIKFC_01619	4.03e-134	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HEKEIKFC_01620	1.43e-173	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HEKEIKFC_01621	1.6e-125	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_01622	3.35e-89	ypoP	-	-	K	-	-	-	transcriptional
HEKEIKFC_01623	1.7e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEKEIKFC_01624	4.61e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HEKEIKFC_01625	1.45e-135	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEKEIKFC_01626	0.0	yokA	-	-	L	-	-	-	Recombinase
HEKEIKFC_01628	2.98e-116	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HEKEIKFC_01629	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEKEIKFC_01630	1.29e-66	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HEKEIKFC_01631	3.29e-115	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HEKEIKFC_01632	2.68e-39	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HEKEIKFC_01636	3.26e-214	-	-	-	S	-	-	-	amine dehydrogenase activity
HEKEIKFC_01639	6.23e-266	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEKEIKFC_01644	3.54e-95	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEKEIKFC_01645	9.09e-282	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HEKEIKFC_01646	1.56e-231	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HEKEIKFC_01647	1.55e-90	cgeA	-	-	-	ko:K06319	-	ko00000	-
HEKEIKFC_01648	3.32e-62	cgeC	-	-	-	ko:K06321	-	ko00000	-
HEKEIKFC_01649	1.97e-316	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HEKEIKFC_01650	4.02e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HEKEIKFC_01652	2.39e-83	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
HEKEIKFC_01653	1.19e-312	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEKEIKFC_01654	6.87e-161	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEKEIKFC_01655	2.68e-159	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEKEIKFC_01656	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HEKEIKFC_01657	1.99e-203	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HEKEIKFC_01658	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HEKEIKFC_01659	2.42e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HEKEIKFC_01660	2.45e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HEKEIKFC_01661	1.9e-161	yodN	-	-	-	-	-	-	-
HEKEIKFC_01663	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
HEKEIKFC_01664	1.83e-134	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HEKEIKFC_01665	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
HEKEIKFC_01667	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HEKEIKFC_01668	4.49e-192	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HEKEIKFC_01669	6.87e-50	yodI	-	-	-	-	-	-	-
HEKEIKFC_01670	1.76e-165	yodH	-	-	Q	-	-	-	Methyltransferase
HEKEIKFC_01671	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HEKEIKFC_01672	1.23e-169	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_01673	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEKEIKFC_01674	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HEKEIKFC_01675	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEKEIKFC_01676	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HEKEIKFC_01677	1.55e-221	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEKEIKFC_01678	7.25e-142	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HEKEIKFC_01679	1.35e-138	yodC	-	-	C	-	-	-	nitroreductase
HEKEIKFC_01680	1.2e-74	yodB	-	-	K	-	-	-	transcriptional
HEKEIKFC_01681	2.74e-92	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HEKEIKFC_01682	2.59e-89	iolK	-	-	S	-	-	-	tautomerase
HEKEIKFC_01684	1.15e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HEKEIKFC_01685	8.49e-210	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HEKEIKFC_01686	1.05e-30	-	-	-	-	-	-	-	-
HEKEIKFC_01687	8.09e-80	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HEKEIKFC_01688	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HEKEIKFC_01689	1.44e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEKEIKFC_01690	4.62e-308	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HEKEIKFC_01692	9.47e-144	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEKEIKFC_01693	7.02e-287	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HEKEIKFC_01694	6.08e-293	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEKEIKFC_01695	2.65e-144	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEKEIKFC_01696	3.45e-208	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HEKEIKFC_01697	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HEKEIKFC_01698	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HEKEIKFC_01699	2.47e-261	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HEKEIKFC_01700	5.46e-181	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HEKEIKFC_01701	9.85e-215	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HEKEIKFC_01702	1.45e-298	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEKEIKFC_01703	4.76e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HEKEIKFC_01704	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HEKEIKFC_01705	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEKEIKFC_01706	4.69e-43	yozC	-	-	-	-	-	-	-
HEKEIKFC_01708	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
HEKEIKFC_01709	6.36e-50	yocN	-	-	-	-	-	-	-
HEKEIKFC_01710	5.58e-59	yozN	-	-	-	-	-	-	-
HEKEIKFC_01711	2.29e-116	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEKEIKFC_01712	3.51e-13	yocN	-	-	-	-	-	-	-
HEKEIKFC_01713	2.71e-13	yocL	-	-	-	-	-	-	-
HEKEIKFC_01714	4.5e-79	yocK	-	-	T	-	-	-	general stress protein
HEKEIKFC_01716	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEKEIKFC_01717	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEKEIKFC_01718	2.8e-167	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HEKEIKFC_01720	1.58e-239	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HEKEIKFC_01721	2.27e-123	yocC	-	-	-	-	-	-	-
HEKEIKFC_01722	2.69e-183	-	-	-	J	-	-	-	Protein required for attachment to host cells
HEKEIKFC_01723	1.33e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HEKEIKFC_01724	1.19e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEKEIKFC_01725	7.69e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HEKEIKFC_01726	3.86e-119	yobW	-	-	-	-	-	-	-
HEKEIKFC_01727	1.1e-171	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEKEIKFC_01728	1.86e-122	yobS	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_01729	3.17e-174	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HEKEIKFC_01730	2.12e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HEKEIKFC_01731	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEKEIKFC_01732	1.15e-113	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HEKEIKFC_01733	3.31e-57	-	-	-	-	-	-	-	-
HEKEIKFC_01734	9.42e-128	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEKEIKFC_01736	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEKEIKFC_01737	2.19e-248	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEKEIKFC_01738	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HEKEIKFC_01739	7.72e-262	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HEKEIKFC_01740	9.01e-178	yoxB	-	-	-	-	-	-	-
HEKEIKFC_01741	6.9e-56	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEKEIKFC_01742	3.49e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_01743	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HEKEIKFC_01744	7.2e-183	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEKEIKFC_01745	3.29e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEKEIKFC_01746	3.04e-204	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_01747	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HEKEIKFC_01748	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HEKEIKFC_01749	3.07e-240	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEKEIKFC_01750	1.29e-199	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_01751	3.67e-18	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEKEIKFC_01752	3.29e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
HEKEIKFC_01753	5.59e-255	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
HEKEIKFC_01754	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HEKEIKFC_01755	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HEKEIKFC_01756	3.97e-125	-	-	-	L	-	-	-	Integrase
HEKEIKFC_01758	3.68e-125	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HEKEIKFC_01759	2.13e-311	yoeA	-	-	V	-	-	-	MATE efflux family protein
HEKEIKFC_01760	1.93e-239	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HEKEIKFC_01761	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HEKEIKFC_01762	3.75e-211	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HEKEIKFC_01763	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
HEKEIKFC_01764	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HEKEIKFC_01765	1.39e-111	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HEKEIKFC_01766	2.79e-313	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HEKEIKFC_01767	1.91e-239	ygaE	-	-	S	-	-	-	Membrane
HEKEIKFC_01768	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HEKEIKFC_01769	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HEKEIKFC_01770	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HEKEIKFC_01771	4.77e-06	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HEKEIKFC_01772	3.81e-173	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_01773	2.54e-50	yfhS	-	-	-	-	-	-	-
HEKEIKFC_01774	1.85e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HEKEIKFC_01775	1.7e-235	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HEKEIKFC_01776	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HEKEIKFC_01777	1.35e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEKEIKFC_01778	9.27e-217	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HEKEIKFC_01779	1.48e-57	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HEKEIKFC_01780	9.84e-123	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HEKEIKFC_01781	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
HEKEIKFC_01782	2.45e-216	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HEKEIKFC_01784	4.06e-268	yfhI	-	-	EGP	-	-	-	-transporter
HEKEIKFC_01785	1.12e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HEKEIKFC_01786	3.14e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HEKEIKFC_01787	4.94e-214	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HEKEIKFC_01789	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
HEKEIKFC_01790	1.17e-137	yfhC	-	-	C	-	-	-	nitroreductase
HEKEIKFC_01791	2.26e-212	yfhB	-	-	S	-	-	-	PhzF family
HEKEIKFC_01792	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEKEIKFC_01793	1.38e-108	yfiV	-	-	K	-	-	-	transcriptional
HEKEIKFC_01794	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HEKEIKFC_01795	1.14e-128	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HEKEIKFC_01796	2.87e-61	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HEKEIKFC_01797	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HEKEIKFC_01798	5.66e-238	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEKEIKFC_01799	4.22e-143	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HEKEIKFC_01800	5.62e-126	padR	-	-	K	-	-	-	transcriptional
HEKEIKFC_01801	2.08e-214	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEKEIKFC_01802	2.73e-204	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HEKEIKFC_01803	5.54e-82	yfiD3	-	-	S	-	-	-	DoxX
HEKEIKFC_01804	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEKEIKFC_01805	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HEKEIKFC_01806	0.0	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HEKEIKFC_01807	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_01808	1.28e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HEKEIKFC_01809	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEKEIKFC_01810	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HEKEIKFC_01811	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HEKEIKFC_01812	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEKEIKFC_01813	2.67e-272	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEKEIKFC_01814	3.08e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEKEIKFC_01815	5.55e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEKEIKFC_01816	2.71e-116	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEKEIKFC_01817	2.97e-245	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEKEIKFC_01819	2.15e-67	-	-	-	S	-	-	-	YfzA-like protein
HEKEIKFC_01820	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEKEIKFC_01821	1.72e-208	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEKEIKFC_01822	2.24e-236	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HEKEIKFC_01824	2.39e-194	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEKEIKFC_01825	4.36e-199	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HEKEIKFC_01826	7.99e-37	yfjT	-	-	-	-	-	-	-
HEKEIKFC_01827	8.03e-280	yfkA	-	-	S	-	-	-	YfkB-like domain
HEKEIKFC_01828	5.2e-189	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HEKEIKFC_01829	5.66e-186	yfkD	-	-	S	-	-	-	YfkD-like protein
HEKEIKFC_01830	8.42e-239	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HEKEIKFC_01831	1.45e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_01832	6.71e-12	-	-	-	-	-	-	-	-
HEKEIKFC_01833	1.37e-185	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HEKEIKFC_01834	2.93e-67	yfkI	-	-	S	-	-	-	gas vesicle protein
HEKEIKFC_01835	6.88e-112	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEKEIKFC_01836	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HEKEIKFC_01837	4.7e-250	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_01838	4.11e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEKEIKFC_01839	6.12e-210	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEKEIKFC_01840	9.13e-239	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HEKEIKFC_01841	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HEKEIKFC_01842	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HEKEIKFC_01843	1.33e-256	yibE	-	-	S	-	-	-	YibE/F-like protein
HEKEIKFC_01844	4.93e-166	yibF	-	-	S	-	-	-	YibE/F-like protein
HEKEIKFC_01845	1.45e-158	frp	-	-	C	-	-	-	nitroreductase
HEKEIKFC_01846	9.69e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HEKEIKFC_01847	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEKEIKFC_01848	5.23e-312	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_01849	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HEKEIKFC_01850	8.17e-52	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HEKEIKFC_01851	8.64e-106	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEKEIKFC_01852	3.45e-83	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HEKEIKFC_01853	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HEKEIKFC_01854	1.87e-98	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HEKEIKFC_01855	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HEKEIKFC_01856	6.62e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HEKEIKFC_01857	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HEKEIKFC_01858	1.98e-26	yflI	-	-	-	-	-	-	-
HEKEIKFC_01859	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HEKEIKFC_01860	2.41e-156	yflK	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_01861	9.63e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HEKEIKFC_01862	1.67e-276	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEKEIKFC_01863	9.44e-190	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEKEIKFC_01864	8.19e-287	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HEKEIKFC_01865	1.88e-224	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HEKEIKFC_01866	1.96e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HEKEIKFC_01867	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEKEIKFC_01868	4.77e-105	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HEKEIKFC_01869	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HEKEIKFC_01870	3.54e-193	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEKEIKFC_01871	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
HEKEIKFC_01876	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HEKEIKFC_01877	4.21e-304	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HEKEIKFC_01878	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HEKEIKFC_01879	1.1e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HEKEIKFC_01880	4.91e-241	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HEKEIKFC_01881	4.87e-85	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
HEKEIKFC_01882	1.53e-265	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HEKEIKFC_01883	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEKEIKFC_01884	1.25e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HEKEIKFC_01885	8.7e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HEKEIKFC_01886	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEKEIKFC_01887	3.45e-265	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEKEIKFC_01888	8.54e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEKEIKFC_01889	2.04e-162	yfmS	-	-	NT	-	-	-	chemotaxis protein
HEKEIKFC_01890	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEKEIKFC_01891	3.41e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HEKEIKFC_01892	5.22e-276	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_01893	1.35e-236	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HEKEIKFC_01894	1.63e-281	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HEKEIKFC_01895	5.44e-229	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HEKEIKFC_01896	6.8e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HEKEIKFC_01897	1.02e-188	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HEKEIKFC_01898	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HEKEIKFC_01899	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HEKEIKFC_01900	1.38e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HEKEIKFC_01901	1.58e-260	yetM	-	-	CH	-	-	-	FAD binding domain
HEKEIKFC_01902	4.2e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEKEIKFC_01904	2.19e-136	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HEKEIKFC_01905	1.06e-72	-	-	-	H	-	-	-	riboflavin kinase activity
HEKEIKFC_01906	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HEKEIKFC_01907	1.27e-196	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEKEIKFC_01908	1.32e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEKEIKFC_01909	1.11e-72	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HEKEIKFC_01910	1.81e-156	yetF	-	-	S	-	-	-	membrane
HEKEIKFC_01911	4.2e-05	-	-	-	-	-	-	-	-
HEKEIKFC_01912	8.73e-127	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HEKEIKFC_01913	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HEKEIKFC_01914	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HEKEIKFC_01915	2.67e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HEKEIKFC_01917	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HEKEIKFC_01918	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HEKEIKFC_01919	1.31e-73	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEKEIKFC_01920	2e-97	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEKEIKFC_01922	7.28e-56	-	-	-	S	-	-	-	Immunity protein 22
HEKEIKFC_01923	1.67e-118	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HEKEIKFC_01924	2.48e-66	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEKEIKFC_01925	1.63e-80	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEKEIKFC_01926	6.78e-176	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HEKEIKFC_01927	9.62e-203	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEKEIKFC_01929	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEKEIKFC_01930	4.95e-216	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEKEIKFC_01931	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEKEIKFC_01932	6.66e-199	yerO	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_01933	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEKEIKFC_01934	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEKEIKFC_01935	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEKEIKFC_01936	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEKEIKFC_01937	1.68e-157	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HEKEIKFC_01938	1.48e-247	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HEKEIKFC_01939	2.74e-286	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HEKEIKFC_01940	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEKEIKFC_01941	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HEKEIKFC_01942	1.76e-163	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HEKEIKFC_01943	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HEKEIKFC_01944	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_01945	7.32e-248	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HEKEIKFC_01946	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HEKEIKFC_01947	4.18e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HEKEIKFC_01948	1.4e-298	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HEKEIKFC_01949	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HEKEIKFC_01950	7.3e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEKEIKFC_01951	2.53e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HEKEIKFC_01952	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEKEIKFC_01953	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEKEIKFC_01954	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEKEIKFC_01955	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEKEIKFC_01956	7.13e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HEKEIKFC_01957	6.38e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEKEIKFC_01958	4.56e-287	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEKEIKFC_01959	1.13e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEKEIKFC_01960	6.56e-40	yebG	-	-	S	-	-	-	NETI protein
HEKEIKFC_01961	4.41e-119	yebE	-	-	S	-	-	-	UPF0316 protein
HEKEIKFC_01963	2.02e-173	yebC	-	-	M	-	-	-	Membrane
HEKEIKFC_01964	1.75e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEKEIKFC_01965	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HEKEIKFC_01966	4.67e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEKEIKFC_01967	3.32e-165	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HEKEIKFC_01968	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HEKEIKFC_01969	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HEKEIKFC_01970	2.69e-275	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HEKEIKFC_01971	6.84e-227	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HEKEIKFC_01972	5.03e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEKEIKFC_01973	1.24e-314	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HEKEIKFC_01974	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HEKEIKFC_01975	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HEKEIKFC_01977	1.43e-194	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HEKEIKFC_01978	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
HEKEIKFC_01979	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HEKEIKFC_01980	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEKEIKFC_01981	1.04e-188	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HEKEIKFC_01982	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HEKEIKFC_01983	8.25e-210	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HEKEIKFC_01984	3.88e-163	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HEKEIKFC_01985	1.55e-229	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEKEIKFC_01986	1.36e-146	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HEKEIKFC_01987	5.98e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HEKEIKFC_01988	4.24e-221	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HEKEIKFC_01989	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HEKEIKFC_01990	1.14e-253	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HEKEIKFC_01991	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HEKEIKFC_01992	4.21e-220	-	-	-	O	ko:K20486	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000,ko01002	COG1404 Subtilisin-like serine proteases
HEKEIKFC_01993	2.68e-117	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_01994	4.62e-85	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_01995	2.62e-144	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_01996	7.82e-35	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HEKEIKFC_01997	9.86e-142	mrsE1	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_01998	5.74e-124	bcrB1	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_01999	1.23e-174	bcrA1	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_02000	4.13e-43	-	-	-	-	-	-	-	-
HEKEIKFC_02001	6.02e-266	lanT	-	-	V	ko:K06148,ko:K13409,ko:K20344,ko:K20386	ko02010,ko02024,ko04626,map02010,map02024,map04626	ko00000,ko00001,ko00002,ko02000,ko02044	Peptidase C39 family
HEKEIKFC_02002	3.93e-164	-	-	-	V	-	-	-	PFAM Lanthionine synthetase
HEKEIKFC_02005	2.8e-240	lcnDR2	-	-	V	-	-	-	Lanthionine synthetase C-like protein
HEKEIKFC_02007	1.27e-71	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HEKEIKFC_02008	2.28e-72	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	accessory gene regulator B
HEKEIKFC_02010	5.94e-119	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HEKEIKFC_02011	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEKEIKFC_02012	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEKEIKFC_02013	8.26e-165	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEKEIKFC_02014	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HEKEIKFC_02015	1.65e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEKEIKFC_02016	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEKEIKFC_02017	1.29e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEKEIKFC_02018	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEKEIKFC_02019	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HEKEIKFC_02020	9.22e-245	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEKEIKFC_02021	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEKEIKFC_02022	8.36e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HEKEIKFC_02023	9.02e-113	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HEKEIKFC_02024	4.87e-234	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEKEIKFC_02027	5.73e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEKEIKFC_02028	5.07e-260	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HEKEIKFC_02029	6.13e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEKEIKFC_02030	1.62e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEKEIKFC_02031	6.04e-291	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEKEIKFC_02032	9.06e-151	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HEKEIKFC_02033	2.46e-169	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HEKEIKFC_02034	2.03e-212	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEKEIKFC_02035	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEKEIKFC_02036	2.93e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HEKEIKFC_02037	7.79e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEKEIKFC_02038	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEKEIKFC_02039	2.05e-180	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HEKEIKFC_02040	2.35e-101	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEKEIKFC_02041	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEKEIKFC_02042	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEKEIKFC_02043	3.96e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEKEIKFC_02044	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HEKEIKFC_02045	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HEKEIKFC_02046	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEKEIKFC_02047	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEKEIKFC_02048	3.97e-172	yphF	-	-	-	-	-	-	-
HEKEIKFC_02049	3.25e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HEKEIKFC_02050	8.18e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HEKEIKFC_02051	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HEKEIKFC_02052	8.79e-136	yphA	-	-	-	-	-	-	-
HEKEIKFC_02053	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
HEKEIKFC_02054	3.28e-235	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEKEIKFC_02055	8.14e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HEKEIKFC_02056	2.87e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HEKEIKFC_02057	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HEKEIKFC_02058	3.35e-06	ypfA	-	-	M	-	-	-	glycosyltransferase
HEKEIKFC_02059	5.02e-31	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HEKEIKFC_02060	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HEKEIKFC_02061	2.54e-211	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HEKEIKFC_02062	6.4e-156	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HEKEIKFC_02063	1.85e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HEKEIKFC_02064	1.81e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEKEIKFC_02065	3.35e-137	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEKEIKFC_02066	1.4e-190	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HEKEIKFC_02067	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HEKEIKFC_02068	3.55e-133	ypbE	-	-	M	-	-	-	Lysin motif
HEKEIKFC_02069	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HEKEIKFC_02070	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEKEIKFC_02071	1.05e-253	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HEKEIKFC_02072	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HEKEIKFC_02073	6.2e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEKEIKFC_02074	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEKEIKFC_02075	4.07e-249	rsiX	-	-	-	-	-	-	-
HEKEIKFC_02076	3.22e-135	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEKEIKFC_02077	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_02078	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_02079	1.26e-251	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HEKEIKFC_02080	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HEKEIKFC_02081	4.31e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEKEIKFC_02082	7.38e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEKEIKFC_02083	3.66e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HEKEIKFC_02084	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HEKEIKFC_02085	9.35e-275	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEKEIKFC_02086	6.14e-122	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HEKEIKFC_02087	7.84e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEKEIKFC_02088	2.85e-164	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEKEIKFC_02090	1.99e-121	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HEKEIKFC_02091	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEKEIKFC_02092	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEKEIKFC_02093	1.8e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEKEIKFC_02094	4.64e-143	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HEKEIKFC_02095	3.09e-267	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEKEIKFC_02096	2.01e-70	ypuD	-	-	-	-	-	-	-
HEKEIKFC_02097	6.56e-131	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEKEIKFC_02098	5.56e-105	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
HEKEIKFC_02099	4.12e-104	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEKEIKFC_02100	3.65e-198	ypuA	-	-	S	-	-	-	Secreted protein
HEKEIKFC_02101	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEKEIKFC_02102	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HEKEIKFC_02103	1.52e-141	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HEKEIKFC_02104	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HEKEIKFC_02105	8.19e-244	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HEKEIKFC_02106	9.92e-104	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HEKEIKFC_02107	1.43e-78	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HEKEIKFC_02108	4.7e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HEKEIKFC_02109	2.77e-173	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEKEIKFC_02110	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEKEIKFC_02111	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HEKEIKFC_02112	1.74e-273	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEKEIKFC_02113	2.6e-191	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEKEIKFC_02114	2.03e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEKEIKFC_02115	2.17e-211	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HEKEIKFC_02116	9.51e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HEKEIKFC_02117	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HEKEIKFC_02118	2.04e-141	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HEKEIKFC_02119	2.63e-08	yqkK	-	-	-	-	-	-	-
HEKEIKFC_02120	1.96e-30	-	-	-	-	-	-	-	-
HEKEIKFC_02121	8.31e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HEKEIKFC_02122	5.89e-312	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HEKEIKFC_02123	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HEKEIKFC_02124	1.3e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HEKEIKFC_02125	1.15e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02126	1.19e-279	yqxK	-	-	L	-	-	-	DNA helicase
HEKEIKFC_02127	4.25e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HEKEIKFC_02128	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HEKEIKFC_02129	1.47e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HEKEIKFC_02130	1.45e-11	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HEKEIKFC_02131	9.23e-223	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HEKEIKFC_02132	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HEKEIKFC_02133	5.4e-80	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HEKEIKFC_02134	1.44e-223	yqkA	-	-	K	-	-	-	GrpB protein
HEKEIKFC_02135	1.71e-80	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HEKEIKFC_02136	2.81e-115	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HEKEIKFC_02137	1.15e-299	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEKEIKFC_02138	9.19e-76	-	-	-	S	-	-	-	YolD-like protein
HEKEIKFC_02140	8.33e-238	yueF	-	-	S	-	-	-	transporter activity
HEKEIKFC_02142	2.67e-96	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEKEIKFC_02143	4.46e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HEKEIKFC_02144	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HEKEIKFC_02145	3.39e-180	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_02146	1.32e-221	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEKEIKFC_02147	8.27e-187	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEKEIKFC_02148	6.86e-175	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HEKEIKFC_02149	4.33e-306	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HEKEIKFC_02150	1.98e-281	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEKEIKFC_02151	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEKEIKFC_02152	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_02153	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_02154	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_02155	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_02156	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_02157	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_02158	1.32e-166	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HEKEIKFC_02159	3.89e-314	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEKEIKFC_02162	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEKEIKFC_02163	6.14e-122	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HEKEIKFC_02164	1.73e-42	-	-	-	S	-	-	-	GlpM protein
HEKEIKFC_02165	1.27e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEKEIKFC_02166	2.72e-190	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEKEIKFC_02167	2.1e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEKEIKFC_02168	4.59e-219	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEKEIKFC_02169	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEKEIKFC_02170	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEKEIKFC_02171	3.31e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEKEIKFC_02172	1.3e-34	yqzJ	-	-	-	-	-	-	-
HEKEIKFC_02173	2.05e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEKEIKFC_02174	8.71e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HEKEIKFC_02175	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEKEIKFC_02176	4.64e-96	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HEKEIKFC_02178	2.14e-122	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_02179	1.6e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HEKEIKFC_02180	2.58e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEKEIKFC_02181	1.04e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEKEIKFC_02182	5.83e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEKEIKFC_02183	4.83e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HEKEIKFC_02184	9.62e-216	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEKEIKFC_02185	7.25e-284	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEKEIKFC_02186	1.7e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEKEIKFC_02187	2.75e-222	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEKEIKFC_02188	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEKEIKFC_02189	6.96e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HEKEIKFC_02190	1.58e-261	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEKEIKFC_02191	1.67e-195	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HEKEIKFC_02192	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HEKEIKFC_02193	7.32e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HEKEIKFC_02194	4e-205	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEKEIKFC_02195	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HEKEIKFC_02196	8.44e-262	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEKEIKFC_02197	1.51e-261	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HEKEIKFC_02198	6.9e-197	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HEKEIKFC_02199	1.13e-271	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HEKEIKFC_02200	1.56e-174	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HEKEIKFC_02201	1.39e-136	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HEKEIKFC_02203	1.32e-129	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEKEIKFC_02204	6.93e-147	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
HEKEIKFC_02206	3.23e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HEKEIKFC_02209	5.23e-277	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEKEIKFC_02210	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEKEIKFC_02211	8.85e-304	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HEKEIKFC_02212	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HEKEIKFC_02213	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HEKEIKFC_02214	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HEKEIKFC_02215	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEKEIKFC_02216	9.49e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEKEIKFC_02217	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEKEIKFC_02218	1.95e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEKEIKFC_02219	3.05e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEKEIKFC_02220	2.2e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEKEIKFC_02221	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_02222	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEKEIKFC_02223	2.32e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEKEIKFC_02224	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HEKEIKFC_02225	2.86e-149	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HEKEIKFC_02226	1.05e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HEKEIKFC_02227	5.23e-261	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HEKEIKFC_02228	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HEKEIKFC_02229	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HEKEIKFC_02230	1.7e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HEKEIKFC_02231	2.56e-220	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HEKEIKFC_02232	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HEKEIKFC_02233	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEKEIKFC_02234	5.18e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HEKEIKFC_02235	3.99e-118	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HEKEIKFC_02236	1.04e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HEKEIKFC_02237	7.65e-83	yqhP	-	-	-	-	-	-	-
HEKEIKFC_02238	7e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HEKEIKFC_02239	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HEKEIKFC_02240	1.12e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HEKEIKFC_02241	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HEKEIKFC_02242	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEKEIKFC_02243	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEKEIKFC_02244	2.24e-262	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HEKEIKFC_02245	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEKEIKFC_02246	3.57e-194	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HEKEIKFC_02247	2.31e-32	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HEKEIKFC_02248	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HEKEIKFC_02249	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HEKEIKFC_02250	3.13e-101	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HEKEIKFC_02251	4.47e-154	yqxM	-	-	-	ko:K19433	-	ko00000	-
HEKEIKFC_02252	6.88e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HEKEIKFC_02253	2e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
HEKEIKFC_02254	4.9e-83	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HEKEIKFC_02255	1.82e-84	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HEKEIKFC_02256	1.56e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HEKEIKFC_02257	2.37e-95	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
HEKEIKFC_02258	9e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HEKEIKFC_02259	4.65e-233	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HEKEIKFC_02260	1.1e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEKEIKFC_02261	6.43e-239	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HEKEIKFC_02262	6.5e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEKEIKFC_02263	2.05e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEKEIKFC_02265	1.15e-86	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HEKEIKFC_02266	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HEKEIKFC_02267	3.45e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HEKEIKFC_02268	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HEKEIKFC_02269	6.04e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
HEKEIKFC_02270	1.55e-255	yqgU	-	-	-	-	-	-	-
HEKEIKFC_02271	2.06e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HEKEIKFC_02272	1.18e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HEKEIKFC_02273	1.21e-274	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HEKEIKFC_02274	5.38e-11	yqgO	-	-	-	-	-	-	-
HEKEIKFC_02275	2.03e-124	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEKEIKFC_02276	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEKEIKFC_02277	3.42e-68	yqzD	-	-	-	-	-	-	-
HEKEIKFC_02278	2.5e-99	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEKEIKFC_02279	2.32e-188	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEKEIKFC_02280	1.44e-186	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEKEIKFC_02281	2.39e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HEKEIKFC_02282	6.1e-204	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HEKEIKFC_02283	2.72e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HEKEIKFC_02284	6.96e-07	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HEKEIKFC_02285	3.74e-138	tmrB	-	-	S	-	-	-	AAA domain
HEKEIKFC_02286	1.34e-188	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HEKEIKFC_02287	3.2e-302	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_02288	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEKEIKFC_02289	1.63e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HEKEIKFC_02290	4.33e-189	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HEKEIKFC_02291	1.12e-215	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HEKEIKFC_02292	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEKEIKFC_02293	7.72e-312	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEKEIKFC_02294	1.17e-289	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HEKEIKFC_02295	4.73e-242	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HEKEIKFC_02296	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HEKEIKFC_02297	5.95e-75	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HEKEIKFC_02298	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEKEIKFC_02299	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEKEIKFC_02300	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
HEKEIKFC_02301	9.53e-284	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HEKEIKFC_02302	1.59e-286	yciC	-	-	S	-	-	-	GTPases (G3E family)
HEKEIKFC_02303	2.5e-281	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEKEIKFC_02304	2.67e-96	yckC	-	-	S	-	-	-	membrane
HEKEIKFC_02305	1.92e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HEKEIKFC_02306	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEKEIKFC_02307	6.79e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HEKEIKFC_02308	1.88e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HEKEIKFC_02309	3.11e-124	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HEKEIKFC_02310	3.14e-139	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HEKEIKFC_02311	1.38e-82	hxlR	-	-	K	-	-	-	transcriptional
HEKEIKFC_02312	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_02313	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_02314	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEKEIKFC_02315	3.05e-180	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HEKEIKFC_02316	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
HEKEIKFC_02317	3.17e-83	-	-	-	S	-	-	-	YcxB-like protein
HEKEIKFC_02318	7.86e-217	ycxC	-	-	EG	-	-	-	EamA-like transporter family
HEKEIKFC_02319	1.69e-313	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
HEKEIKFC_02320	1.11e-168	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HEKEIKFC_02321	1.22e-141	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HEKEIKFC_02322	3.24e-168	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEKEIKFC_02323	3.03e-154	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEKEIKFC_02324	2.8e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HEKEIKFC_02325	1.4e-204	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HEKEIKFC_02326	1.99e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEKEIKFC_02327	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HEKEIKFC_02328	2.83e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HEKEIKFC_02329	2.37e-100	yclD	-	-	-	-	-	-	-
HEKEIKFC_02330	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HEKEIKFC_02331	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HEKEIKFC_02333	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HEKEIKFC_02334	5.93e-302	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HEKEIKFC_02335	9.23e-249	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HEKEIKFC_02336	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEKEIKFC_02337	3.64e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEKEIKFC_02338	1.56e-183	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEKEIKFC_02339	1.49e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEKEIKFC_02340	1.38e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_02341	6.87e-277	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HEKEIKFC_02342	9.28e-317	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HEKEIKFC_02343	2.21e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HEKEIKFC_02344	3.59e-304	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HEKEIKFC_02345	9.08e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_02346	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HEKEIKFC_02347	1.2e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEKEIKFC_02349	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEKEIKFC_02350	7.78e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_02351	1.64e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_02352	1.61e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_02353	6.82e-224	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HEKEIKFC_02354	2.1e-315	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HEKEIKFC_02355	1.05e-195	ycnC	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02356	1.38e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HEKEIKFC_02357	1.97e-59	ycnE	-	-	S	-	-	-	Monooxygenase
HEKEIKFC_02358	1.37e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEKEIKFC_02359	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEKEIKFC_02360	7.59e-288	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEKEIKFC_02361	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEKEIKFC_02362	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HEKEIKFC_02363	2.4e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_02364	3.4e-130	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_02365	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HEKEIKFC_02366	4.98e-137	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEKEIKFC_02367	9.6e-73	-	-	-	-	-	-	-	-
HEKEIKFC_02368	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEKEIKFC_02369	2.38e-94	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HEKEIKFC_02370	2.72e-262	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEKEIKFC_02371	3.38e-86	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HEKEIKFC_02373	2.69e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HEKEIKFC_02374	7.14e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HEKEIKFC_02375	7.29e-269	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEKEIKFC_02376	1.98e-191	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HEKEIKFC_02377	6.36e-173	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HEKEIKFC_02378	5.97e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HEKEIKFC_02379	1.89e-166	kipR	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02380	7.47e-148	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HEKEIKFC_02382	5.95e-75	yczJ	-	-	S	-	-	-	biosynthesis
HEKEIKFC_02383	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HEKEIKFC_02384	4.09e-218	ycsN	-	-	S	-	-	-	Oxidoreductase
HEKEIKFC_02385	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HEKEIKFC_02386	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HEKEIKFC_02387	5.2e-205	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_02388	1.59e-124	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HEKEIKFC_02389	1.16e-148	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEKEIKFC_02390	2.14e-100	ydaG	-	-	S	-	-	-	general stress protein
HEKEIKFC_02391	7.59e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HEKEIKFC_02392	5.59e-64	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HEKEIKFC_02393	3.25e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HEKEIKFC_02394	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEKEIKFC_02395	3.83e-256	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEKEIKFC_02396	3.12e-188	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HEKEIKFC_02397	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HEKEIKFC_02398	4.54e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HEKEIKFC_02399	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HEKEIKFC_02400	0.0	ydaO	-	-	E	-	-	-	amino acid
HEKEIKFC_02401	1.86e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HEKEIKFC_02402	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEKEIKFC_02403	4.42e-11	-	-	-	-	-	-	-	-
HEKEIKFC_02405	2.95e-113	-	-	-	-	-	-	-	-
HEKEIKFC_02406	5.04e-130	-	-	-	-	-	-	-	-
HEKEIKFC_02407	7.18e-52	-	-	-	-	-	-	-	-
HEKEIKFC_02408	5.35e-288	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HEKEIKFC_02410	1.95e-45	ydaT	-	-	-	-	-	-	-
HEKEIKFC_02411	7.56e-94	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HEKEIKFC_02412	1.66e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HEKEIKFC_02413	6.56e-183	ydbA	-	-	P	-	-	-	EcsC protein family
HEKEIKFC_02414	2.34e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HEKEIKFC_02415	7.59e-78	ydbB	-	-	G	-	-	-	Cupin domain
HEKEIKFC_02416	2.48e-80	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HEKEIKFC_02417	1.64e-199	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HEKEIKFC_02418	6.33e-254	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEKEIKFC_02419	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEKEIKFC_02420	2.13e-152	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HEKEIKFC_02421	3.91e-287	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEKEIKFC_02422	7.07e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
HEKEIKFC_02423	4.79e-221	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_02424	2.44e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEKEIKFC_02425	2.29e-70	ydbL	-	-	-	-	-	-	-
HEKEIKFC_02426	7.51e-262	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HEKEIKFC_02427	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
HEKEIKFC_02428	1.33e-13	-	-	-	S	-	-	-	Fur-regulated basic protein A
HEKEIKFC_02429	2e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEKEIKFC_02430	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
HEKEIKFC_02431	2.16e-258	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HEKEIKFC_02432	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEKEIKFC_02433	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEKEIKFC_02434	3.8e-106	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HEKEIKFC_02435	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HEKEIKFC_02436	2.08e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HEKEIKFC_02437	1.37e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEKEIKFC_02438	6.39e-235	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HEKEIKFC_02439	4.17e-281	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEKEIKFC_02440	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HEKEIKFC_02441	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HEKEIKFC_02442	1.43e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HEKEIKFC_02443	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HEKEIKFC_02444	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEKEIKFC_02445	3.6e-241	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HEKEIKFC_02446	2.8e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HEKEIKFC_02447	7.1e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HEKEIKFC_02448	1.14e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEKEIKFC_02449	3.33e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HEKEIKFC_02450	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HEKEIKFC_02451	1.78e-21	-	-	-	-	-	-	-	-
HEKEIKFC_02452	1.74e-75	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HEKEIKFC_02460	3.82e-194	yddH	-	-	M	-	-	-	Lysozyme-like
HEKEIKFC_02461	2.14e-79	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEKEIKFC_02462	1.17e-62	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HEKEIKFC_02463	3.5e-59	-	-	-	-	-	-	-	-
HEKEIKFC_02464	2.34e-173	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEKEIKFC_02465	1.35e-124	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HEKEIKFC_02466	6.17e-96	-	-	-	S	-	-	-	SnoaL-like polyketide cyclase
HEKEIKFC_02467	1.49e-179	yddR	-	-	S	-	-	-	Zn-dependent hydrolases of the beta-lactamase fold
HEKEIKFC_02468	2.73e-92	lrpA	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
HEKEIKFC_02469	1.13e-193	-	-	-	S	-	-	-	Serine aminopeptidase, S33
HEKEIKFC_02470	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
HEKEIKFC_02471	1.35e-59	ohrR	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02472	2.6e-103	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
HEKEIKFC_02473	2.05e-94	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HEKEIKFC_02474	3.46e-84	-	-	-	S	-	-	-	YjbR
HEKEIKFC_02475	3.35e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02476	2.22e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HEKEIKFC_02477	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HEKEIKFC_02478	5.92e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HEKEIKFC_02479	4.82e-155	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HEKEIKFC_02480	3.77e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HEKEIKFC_02481	8.2e-68	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HEKEIKFC_02482	1.39e-231	-	-	-	S	-	-	-	Patatin-like phospholipase
HEKEIKFC_02483	2.47e-101	-	-	-	S	-	-	-	DinB superfamily
HEKEIKFC_02484	1.49e-84	-	-	-	G	-	-	-	Cupin domain
HEKEIKFC_02487	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HEKEIKFC_02488	2.63e-41	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEKEIKFC_02489	3.3e-194	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HEKEIKFC_02490	1.5e-254	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HEKEIKFC_02492	1.02e-190	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HEKEIKFC_02494	3.53e-255	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HEKEIKFC_02495	3.04e-73	ydeH	-	-	-	-	-	-	-
HEKEIKFC_02496	5.27e-110	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
HEKEIKFC_02497	3.78e-248	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEKEIKFC_02498	4.34e-189	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HEKEIKFC_02499	1.1e-192	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEKEIKFC_02500	6.9e-298	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HEKEIKFC_02501	1.47e-199	-	-	-	S	-	-	-	Sodium Bile acid symporter family
HEKEIKFC_02502	9.05e-258	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HEKEIKFC_02503	7.29e-87	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HEKEIKFC_02504	7.9e-288	nhaC_1	-	-	C	-	-	-	antiporter
HEKEIKFC_02505	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HEKEIKFC_02506	1.2e-145	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_02508	1.62e-245	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HEKEIKFC_02509	2.43e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02510	7.47e-202	ydeK	-	-	EG	-	-	-	-transporter
HEKEIKFC_02511	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEKEIKFC_02512	5.09e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HEKEIKFC_02513	3.42e-33	yraE	-	-	-	ko:K06440	-	ko00000	-
HEKEIKFC_02514	3.04e-282	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEKEIKFC_02515	4.76e-84	yraF	-	-	M	-	-	-	Spore coat protein
HEKEIKFC_02516	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
HEKEIKFC_02517	7.63e-279	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_02518	6.89e-143	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEKEIKFC_02519	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HEKEIKFC_02520	1.97e-170	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HEKEIKFC_02521	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HEKEIKFC_02522	1.91e-129	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEKEIKFC_02523	3.51e-191	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEKEIKFC_02524	2.68e-248	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HEKEIKFC_02525	8.22e-270	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HEKEIKFC_02526	1.53e-285	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEKEIKFC_02527	2.24e-200	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEKEIKFC_02528	5.2e-157	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEKEIKFC_02529	1.99e-104	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HEKEIKFC_02530	4.83e-15	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEKEIKFC_02531	2.73e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HEKEIKFC_02532	6.64e-188	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HEKEIKFC_02533	1.4e-210	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HEKEIKFC_02534	7.66e-153	ydhC	-	-	K	-	-	-	FCD
HEKEIKFC_02535	9.24e-289	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEKEIKFC_02538	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
HEKEIKFC_02540	4.8e-125	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HEKEIKFC_02541	3.18e-247	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HEKEIKFC_02542	2.06e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HEKEIKFC_02543	3.25e-154	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HEKEIKFC_02544	1.23e-276	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HEKEIKFC_02545	8.58e-65	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HEKEIKFC_02546	4.48e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEKEIKFC_02547	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02548	0.0	ybeC	-	-	E	-	-	-	amino acid
HEKEIKFC_02549	4.41e-214	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HEKEIKFC_02550	2.06e-112	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HEKEIKFC_02551	2.83e-237	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HEKEIKFC_02552	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEKEIKFC_02557	4.05e-166	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HEKEIKFC_02558	9.53e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEKEIKFC_02559	4.5e-234	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HEKEIKFC_02560	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEKEIKFC_02561	8.76e-48	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HEKEIKFC_02562	1.04e-308	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HEKEIKFC_02563	6.15e-187	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HEKEIKFC_02564	1.62e-178	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HEKEIKFC_02565	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HEKEIKFC_02566	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_02567	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEKEIKFC_02568	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HEKEIKFC_02569	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HEKEIKFC_02570	3.95e-293	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEKEIKFC_02571	1.01e-100	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HEKEIKFC_02572	3.66e-152	yoaK	-	-	S	-	-	-	Membrane
HEKEIKFC_02573	2.78e-82	ymzB	-	-	-	-	-	-	-
HEKEIKFC_02574	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HEKEIKFC_02575	1.06e-06	-	-	-	-	-	-	-	-
HEKEIKFC_02576	6.85e-164	ymaC	-	-	S	-	-	-	Replication protein
HEKEIKFC_02577	1.71e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HEKEIKFC_02578	7.46e-72	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEKEIKFC_02579	1.82e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEKEIKFC_02581	5.96e-77	ymaF	-	-	S	-	-	-	YmaF family
HEKEIKFC_02582	7.63e-221	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEKEIKFC_02583	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HEKEIKFC_02584	6e-59	-	-	-	-	-	-	-	-
HEKEIKFC_02585	9.42e-29	ymzA	-	-	-	-	-	-	-
HEKEIKFC_02586	9.34e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HEKEIKFC_02587	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEKEIKFC_02588	5.77e-244	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEKEIKFC_02589	3.18e-141	ymaB	-	-	S	-	-	-	MutT family
HEKEIKFC_02590	6.21e-148	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEKEIKFC_02591	1.28e-225	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HEKEIKFC_02592	5.44e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEKEIKFC_02593	4.1e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HEKEIKFC_02594	5.34e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HEKEIKFC_02595	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HEKEIKFC_02596	2.04e-12	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEKEIKFC_02597	1.2e-24	-	-	-	-	-	-	-	-
HEKEIKFC_02598	8.14e-74	-	-	-	-	-	-	-	-
HEKEIKFC_02600	8.25e-273	mrjp	-	-	G	-	-	-	Major royal jelly protein
HEKEIKFC_02601	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HEKEIKFC_02602	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HEKEIKFC_02603	7.75e-279	xylR	-	-	GK	-	-	-	ROK family
HEKEIKFC_02604	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HEKEIKFC_02605	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HEKEIKFC_02606	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HEKEIKFC_02609	2.21e-27	-	-	-	-	-	-	-	-
HEKEIKFC_02610	1.7e-72	dinB	-	-	S	-	-	-	DinB family
HEKEIKFC_02611	1.2e-236	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HEKEIKFC_02613	6.73e-23	-	-	-	-	-	-	-	-
HEKEIKFC_02614	5.74e-26	yoaW	-	-	-	-	-	-	-
HEKEIKFC_02615	5.72e-06	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HEKEIKFC_02616	4.81e-183	yoaP	-	-	K	-	-	-	YoaP-like
HEKEIKFC_02617	1.34e-127	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEKEIKFC_02619	3.47e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HEKEIKFC_02620	4.15e-258	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEKEIKFC_02621	1.65e-152	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
HEKEIKFC_02622	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEKEIKFC_02623	7.07e-81	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HEKEIKFC_02624	5.24e-124	yvgO	-	-	-	-	-	-	-
HEKEIKFC_02626	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HEKEIKFC_02627	1.49e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HEKEIKFC_02628	4.99e-185	yndL	-	-	S	-	-	-	Replication protein
HEKEIKFC_02629	1.74e-11	-	-	-	-	-	-	-	-
HEKEIKFC_02630	6.29e-185	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HEKEIKFC_02631	3.2e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HEKEIKFC_02633	3.18e-141	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEKEIKFC_02634	1.01e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HEKEIKFC_02635	4.29e-144	yneB	-	-	L	-	-	-	resolvase
HEKEIKFC_02636	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HEKEIKFC_02637	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEKEIKFC_02638	1.08e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HEKEIKFC_02639	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HEKEIKFC_02640	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HEKEIKFC_02641	4.47e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HEKEIKFC_02642	2.47e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HEKEIKFC_02643	2.27e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HEKEIKFC_02644	4.83e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HEKEIKFC_02645	7.01e-82	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HEKEIKFC_02646	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HEKEIKFC_02647	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HEKEIKFC_02648	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEKEIKFC_02649	9.94e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEKEIKFC_02651	1e-43	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HEKEIKFC_02652	1.7e-96	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HEKEIKFC_02653	7.79e-70	yneQ	-	-	-	-	-	-	-
HEKEIKFC_02654	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HEKEIKFC_02655	9.09e-121	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEKEIKFC_02656	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HEKEIKFC_02657	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEKEIKFC_02658	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEKEIKFC_02659	2.21e-19	-	-	-	-	-	-	-	-
HEKEIKFC_02660	1.82e-63	ynfC	-	-	-	-	-	-	-
HEKEIKFC_02661	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HEKEIKFC_02662	3.68e-230	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HEKEIKFC_02663	8.49e-242	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HEKEIKFC_02664	7.48e-147	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HEKEIKFC_02665	2.87e-130	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HEKEIKFC_02666	1.25e-113	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HEKEIKFC_02667	1.06e-193	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_02668	1.5e-232	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HEKEIKFC_02669	3.21e-286	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
HEKEIKFC_02670	6.47e-205	yndG	-	-	S	-	-	-	DoxX-like family
HEKEIKFC_02671	1.11e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HEKEIKFC_02672	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HEKEIKFC_02674	2.99e-34	-	-	-	-	-	-	-	-
HEKEIKFC_02676	1.3e-173	-	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEKEIKFC_02681	4.17e-89	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	Protein of unknown function (DUF1430)
HEKEIKFC_02682	4.96e-83	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEKEIKFC_02685	9.75e-218	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
HEKEIKFC_02686	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
HEKEIKFC_02687	3.64e-70	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
HEKEIKFC_02688	3.42e-312	-	-	-	T	-	-	-	Histidine kinase
HEKEIKFC_02689	1.32e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEKEIKFC_02690	0.0	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HEKEIKFC_02691	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HEKEIKFC_02692	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_02693	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_02694	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_02695	7.24e-283	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEKEIKFC_02696	6.8e-177	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEKEIKFC_02697	4.5e-157	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEKEIKFC_02698	2.56e-161	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEKEIKFC_02699	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HEKEIKFC_02700	1.07e-283	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEKEIKFC_02701	3.22e-246	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HEKEIKFC_02702	1.29e-167	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEKEIKFC_02703	6.83e-274	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEKEIKFC_02704	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HEKEIKFC_02705	2.32e-186	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HEKEIKFC_02706	2.26e-95	yngA	-	-	S	-	-	-	membrane
HEKEIKFC_02707	8.78e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HEKEIKFC_02708	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HEKEIKFC_02709	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEKEIKFC_02710	8.28e-177	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HEKEIKFC_02711	1.48e-215	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HEKEIKFC_02712	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HEKEIKFC_02713	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HEKEIKFC_02714	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEKEIKFC_02715	5.35e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HEKEIKFC_02716	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HEKEIKFC_02717	1.67e-85	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HEKEIKFC_02718	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
HEKEIKFC_02719	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_02720	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_02721	6.35e-27	-	-	-	-	-	-	-	-
HEKEIKFC_02723	1.15e-279	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEKEIKFC_02724	3.37e-272	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEKEIKFC_02725	1.23e-164	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HEKEIKFC_02726	2e-120	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HEKEIKFC_02727	1.05e-97	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEKEIKFC_02729	1.76e-47	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HEKEIKFC_02730	2.48e-171	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEKEIKFC_02731	1.53e-158	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEKEIKFC_02732	2.54e-102	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HEKEIKFC_02733	1.23e-48	-	-	-	-	-	-	-	-
HEKEIKFC_02734	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEKEIKFC_02735	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HEKEIKFC_02736	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEKEIKFC_02739	2.05e-73	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HEKEIKFC_02740	2.67e-68	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HEKEIKFC_02741	8.38e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
HEKEIKFC_02742	4.33e-99	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HEKEIKFC_02743	1.61e-116	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HEKEIKFC_02744	1.12e-103	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HEKEIKFC_02745	3.38e-125	yjbX	-	-	S	-	-	-	Spore coat protein
HEKEIKFC_02746	6.85e-180	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HEKEIKFC_02747	3.03e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEKEIKFC_02748	1.65e-242	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEKEIKFC_02749	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEKEIKFC_02750	5.5e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
HEKEIKFC_02751	5.56e-269	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HEKEIKFC_02752	4.68e-138	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HEKEIKFC_02753	4.88e-178	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEKEIKFC_02754	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEKEIKFC_02755	5.27e-184	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HEKEIKFC_02756	1.65e-211	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEKEIKFC_02757	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEKEIKFC_02758	9.01e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HEKEIKFC_02759	3.5e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HEKEIKFC_02760	1.72e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_02761	3.28e-138	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEKEIKFC_02762	7.06e-93	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HEKEIKFC_02763	2.46e-219	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HEKEIKFC_02764	3.14e-27	-	-	-	-	-	-	-	-
HEKEIKFC_02765	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HEKEIKFC_02766	4.68e-281	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HEKEIKFC_02767	2.8e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEKEIKFC_02768	2.77e-141	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HEKEIKFC_02769	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEKEIKFC_02770	4.4e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEKEIKFC_02771	1.49e-296	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HEKEIKFC_02772	2.19e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_02773	1.5e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_02774	3.59e-210	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKEIKFC_02775	2.53e-213	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKEIKFC_02776	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEKEIKFC_02777	5.9e-233	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HEKEIKFC_02778	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HEKEIKFC_02779	3.87e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKEIKFC_02780	4.24e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKEIKFC_02781	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HEKEIKFC_02782	8.8e-239	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_02783	4.15e-232	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_02784	1.02e-187	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HEKEIKFC_02785	5.48e-300	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEKEIKFC_02786	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEKEIKFC_02787	2.82e-44	yjzB	-	-	-	-	-	-	-
HEKEIKFC_02788	6.46e-37	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HEKEIKFC_02789	1.9e-212	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HEKEIKFC_02790	9.68e-134	yjaV	-	-	-	-	-	-	-
HEKEIKFC_02791	2.14e-176	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HEKEIKFC_02792	1.06e-32	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HEKEIKFC_02793	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
HEKEIKFC_02794	2.89e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEKEIKFC_02795	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HEKEIKFC_02796	6.9e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEKEIKFC_02797	1.97e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HEKEIKFC_02798	1.27e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HEKEIKFC_02799	5.39e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEKEIKFC_02800	8.65e-254	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEKEIKFC_02801	2.39e-121	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HEKEIKFC_02802	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HEKEIKFC_02803	3.22e-103	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HEKEIKFC_02804	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HEKEIKFC_02805	3.05e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HEKEIKFC_02806	2.16e-198	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HEKEIKFC_02807	1.49e-11	-	-	-	-	-	-	-	-
HEKEIKFC_02808	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HEKEIKFC_02809	6.41e-106	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HEKEIKFC_02810	1.61e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEKEIKFC_02811	9.13e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_02813	4.92e-305	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HEKEIKFC_02814	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HEKEIKFC_02815	5.36e-222	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
HEKEIKFC_02816	1.59e-206	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HEKEIKFC_02817	6.39e-79	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HEKEIKFC_02818	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEKEIKFC_02819	3.78e-106	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HEKEIKFC_02820	6.14e-108	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HEKEIKFC_02821	1.68e-239	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEKEIKFC_02822	8.48e-96	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HEKEIKFC_02823	3.11e-116	yisT	-	-	S	-	-	-	DinB family
HEKEIKFC_02824	1.35e-205	yisR	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02825	9.14e-312	yisQ	-	-	V	-	-	-	Mate efflux family protein
HEKEIKFC_02826	2.3e-172	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HEKEIKFC_02827	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HEKEIKFC_02828	1.59e-125	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HEKEIKFC_02829	6.36e-78	yisL	-	-	S	-	-	-	UPF0344 protein
HEKEIKFC_02830	2.43e-193	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEKEIKFC_02831	1.6e-11	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEKEIKFC_02832	1.03e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HEKEIKFC_02833	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HEKEIKFC_02834	3.82e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HEKEIKFC_02835	8.51e-109	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HEKEIKFC_02836	3e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HEKEIKFC_02837	1.61e-84	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HEKEIKFC_02838	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HEKEIKFC_02839	2.18e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HEKEIKFC_02840	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HEKEIKFC_02841	3.31e-283	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEKEIKFC_02842	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HEKEIKFC_02843	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HEKEIKFC_02844	1.07e-152	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEKEIKFC_02845	1.47e-121	yhjR	-	-	S	-	-	-	Rubrerythrin
HEKEIKFC_02846	3.71e-140	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
HEKEIKFC_02847	1.78e-266	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_02848	9.85e-262	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HEKEIKFC_02849	4.89e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEKEIKFC_02850	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HEKEIKFC_02851	9.51e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEKEIKFC_02852	1.11e-142	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HEKEIKFC_02853	4.12e-79	yhjD	-	-	-	-	-	-	-
HEKEIKFC_02854	1.37e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HEKEIKFC_02855	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEKEIKFC_02856	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HEKEIKFC_02857	1.23e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HEKEIKFC_02858	4.26e-161	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HEKEIKFC_02859	1.96e-104	-	-	-	S	-	-	-	MepB protein
HEKEIKFC_02860	1.12e-87	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HEKEIKFC_02861	1.79e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HEKEIKFC_02862	7.64e-142	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HEKEIKFC_02863	9.48e-43	yhzC	-	-	S	-	-	-	IDEAL
HEKEIKFC_02864	1.35e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_02865	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HEKEIKFC_02866	6.96e-271	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HEKEIKFC_02867	1.86e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HEKEIKFC_02868	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HEKEIKFC_02869	3.02e-254	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HEKEIKFC_02870	6.03e-134	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HEKEIKFC_02871	3.7e-201	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HEKEIKFC_02872	3.46e-265	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEKEIKFC_02873	3.71e-300	yhfN	-	-	O	-	-	-	Peptidase M48
HEKEIKFC_02874	2.38e-86	yhfM	-	-	-	-	-	-	-
HEKEIKFC_02875	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HEKEIKFC_02876	8.98e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
HEKEIKFC_02877	5.31e-241	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HEKEIKFC_02878	6.93e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HEKEIKFC_02880	3.43e-282	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEKEIKFC_02881	2.57e-251	yhfE	-	-	G	-	-	-	peptidase M42
HEKEIKFC_02883	5.68e-233	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEKEIKFC_02884	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HEKEIKFC_02885	3.1e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_02886	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEKEIKFC_02887	2.13e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HEKEIKFC_02888	1.04e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HEKEIKFC_02889	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEKEIKFC_02890	2.55e-116	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HEKEIKFC_02891	1.62e-310	yhfA	-	-	C	-	-	-	membrane
HEKEIKFC_02892	2.95e-284	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEKEIKFC_02893	8.65e-162	ecsC	-	-	S	-	-	-	EcsC protein family
HEKEIKFC_02894	9.11e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HEKEIKFC_02895	1.82e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HEKEIKFC_02896	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEKEIKFC_02897	1.45e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEKEIKFC_02898	1.43e-100	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HEKEIKFC_02899	2.55e-24	-	-	-	-	-	-	-	-
HEKEIKFC_02900	2.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
HEKEIKFC_02901	8.17e-147	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HEKEIKFC_02902	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HEKEIKFC_02903	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HEKEIKFC_02904	1.53e-184	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEKEIKFC_02905	3.48e-44	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HEKEIKFC_02906	2.48e-226	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HEKEIKFC_02907	0.0	yhaN	-	-	L	-	-	-	AAA domain
HEKEIKFC_02908	1.76e-298	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HEKEIKFC_02909	6.55e-275	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HEKEIKFC_02910	3.92e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_02911	7.01e-20	-	-	-	S	-	-	-	YhzD-like protein
HEKEIKFC_02912	4.11e-175	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HEKEIKFC_02914	1.87e-113	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HEKEIKFC_02915	1.41e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HEKEIKFC_02916	1.92e-316	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
HEKEIKFC_02917	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HEKEIKFC_02918	2.83e-203	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HEKEIKFC_02919	1.13e-254	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
HEKEIKFC_02920	3.3e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HEKEIKFC_02921	3.19e-263	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HEKEIKFC_02922	4.41e-272	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HEKEIKFC_02923	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HEKEIKFC_02924	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HEKEIKFC_02925	3.3e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HEKEIKFC_02927	1.11e-141	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HEKEIKFC_02928	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEKEIKFC_02929	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEKEIKFC_02931	1.24e-110	-	-	-	T	-	-	-	universal stress protein
HEKEIKFC_02932	1.55e-123	ymcC	-	-	S	-	-	-	Membrane
HEKEIKFC_02933	1e-113	pksA	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_02934	5.67e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HEKEIKFC_02935	4.69e-199	nodB1	-	-	G	-	-	-	deacetylase
HEKEIKFC_02936	1.19e-179	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEKEIKFC_02937	1.91e-261	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HEKEIKFC_02938	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HEKEIKFC_02939	1.23e-163	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HEKEIKFC_02940	7.92e-76	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEKEIKFC_02941	1.75e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEKEIKFC_02942	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEKEIKFC_02943	1.84e-299	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEKEIKFC_02944	2.01e-286	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HEKEIKFC_02945	1.97e-92	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HEKEIKFC_02946	3.94e-307	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEKEIKFC_02947	8.84e-140	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEKEIKFC_02948	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEKEIKFC_02949	1.69e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HEKEIKFC_02950	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HEKEIKFC_02951	2.8e-265	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEKEIKFC_02952	1.78e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HEKEIKFC_02953	1.3e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_02954	2.83e-262	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEKEIKFC_02955	7e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_02956	2.62e-176	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEKEIKFC_02957	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HEKEIKFC_02958	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HEKEIKFC_02959	0.0	ygxB	-	-	M	-	-	-	Conserved TM helix
HEKEIKFC_02960	1.32e-96	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HEKEIKFC_02961	1.41e-295	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEKEIKFC_02962	6.94e-70	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HEKEIKFC_02963	6.98e-53	yhdB	-	-	S	-	-	-	YhdB-like protein
HEKEIKFC_02964	1.02e-117	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HEKEIKFC_02965	1.05e-143	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEKEIKFC_02966	9.99e-99	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_02967	3.6e-138	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_02968	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HEKEIKFC_02969	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEKEIKFC_02970	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEKEIKFC_02971	9.46e-198	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEKEIKFC_02972	5.16e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEKEIKFC_02973	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEKEIKFC_02974	8.47e-87	ylbD	-	-	S	-	-	-	Putative coat protein
HEKEIKFC_02975	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HEKEIKFC_02976	3.33e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HEKEIKFC_02977	2.78e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
HEKEIKFC_02978	1.81e-114	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HEKEIKFC_02979	1.01e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEKEIKFC_02980	2.91e-277	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HEKEIKFC_02981	2.48e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HEKEIKFC_02982	1.52e-240	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HEKEIKFC_02983	1.43e-292	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HEKEIKFC_02984	4.88e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HEKEIKFC_02985	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HEKEIKFC_02986	3.13e-111	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEKEIKFC_02987	1.14e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
HEKEIKFC_02988	1.68e-210	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEKEIKFC_02989	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HEKEIKFC_02990	1.78e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HEKEIKFC_02991	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEKEIKFC_02992	2.4e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
HEKEIKFC_02993	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEKEIKFC_02994	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HEKEIKFC_02995	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEKEIKFC_02996	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEKEIKFC_02997	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEKEIKFC_02998	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEKEIKFC_02999	4.67e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEKEIKFC_03000	9.58e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HEKEIKFC_03001	3.8e-179	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEKEIKFC_03002	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEKEIKFC_03003	2.61e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEKEIKFC_03004	1.54e-167	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HEKEIKFC_03005	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HEKEIKFC_03006	5.55e-216	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HEKEIKFC_03007	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEKEIKFC_03008	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEKEIKFC_03009	1.33e-185	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HEKEIKFC_03010	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HEKEIKFC_03011	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
HEKEIKFC_03012	9.55e-206	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HEKEIKFC_03013	5.23e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEKEIKFC_03014	7.98e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEKEIKFC_03015	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HEKEIKFC_03016	3.54e-181	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HEKEIKFC_03017	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HEKEIKFC_03018	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEKEIKFC_03019	1.79e-84	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HEKEIKFC_03020	1.24e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEKEIKFC_03021	3.09e-215	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEKEIKFC_03022	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEKEIKFC_03023	1.39e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HEKEIKFC_03024	3.61e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HEKEIKFC_03025	1.28e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEKEIKFC_03026	3.09e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEKEIKFC_03027	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HEKEIKFC_03028	1.01e-180	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEKEIKFC_03029	7.36e-222	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEKEIKFC_03030	5.2e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEKEIKFC_03031	4.44e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEKEIKFC_03033	9.88e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HEKEIKFC_03034	8.54e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HEKEIKFC_03035	3.72e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HEKEIKFC_03036	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HEKEIKFC_03037	3.41e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HEKEIKFC_03038	7.18e-188	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HEKEIKFC_03039	6.27e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HEKEIKFC_03040	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HEKEIKFC_03041	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HEKEIKFC_03042	3.04e-198	yloC	-	-	S	-	-	-	stress-induced protein
HEKEIKFC_03043	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HEKEIKFC_03044	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HEKEIKFC_03045	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEKEIKFC_03046	2.18e-287	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEKEIKFC_03047	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEKEIKFC_03048	5e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEKEIKFC_03049	7.57e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEKEIKFC_03050	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEKEIKFC_03051	1.52e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEKEIKFC_03052	3.51e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HEKEIKFC_03053	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HEKEIKFC_03054	6.22e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEKEIKFC_03055	2.31e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HEKEIKFC_03056	1.3e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HEKEIKFC_03057	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HEKEIKFC_03058	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03059	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HEKEIKFC_03060	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HEKEIKFC_03061	2.4e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HEKEIKFC_03062	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEKEIKFC_03063	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HEKEIKFC_03064	3.14e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEKEIKFC_03065	3.76e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEKEIKFC_03066	8.61e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HEKEIKFC_03067	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEKEIKFC_03068	6.09e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEKEIKFC_03069	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HEKEIKFC_03070	1.87e-224	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEKEIKFC_03071	2.44e-180	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HEKEIKFC_03072	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEKEIKFC_03073	1.16e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEKEIKFC_03074	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HEKEIKFC_03075	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HEKEIKFC_03076	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
HEKEIKFC_03077	1.51e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEKEIKFC_03078	3.42e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HEKEIKFC_03079	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEKEIKFC_03080	7.24e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEKEIKFC_03081	4.59e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEKEIKFC_03082	0.0	ylqG	-	-	-	-	-	-	-
HEKEIKFC_03083	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HEKEIKFC_03084	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEKEIKFC_03085	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEKEIKFC_03086	1.27e-216	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HEKEIKFC_03087	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEKEIKFC_03088	3.83e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEKEIKFC_03089	3.64e-219	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HEKEIKFC_03090	7.38e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEKEIKFC_03091	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEKEIKFC_03092	2.77e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEKEIKFC_03093	8.02e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HEKEIKFC_03094	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HEKEIKFC_03095	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HEKEIKFC_03096	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HEKEIKFC_03097	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEKEIKFC_03098	9.29e-121	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HEKEIKFC_03099	1.74e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HEKEIKFC_03100	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HEKEIKFC_03101	1.98e-88	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HEKEIKFC_03102	7.04e-259	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HEKEIKFC_03103	8.9e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HEKEIKFC_03104	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HEKEIKFC_03105	7.7e-80	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HEKEIKFC_03106	5.43e-230	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEKEIKFC_03107	4.91e-247	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEKEIKFC_03108	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HEKEIKFC_03109	9.34e-144	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HEKEIKFC_03110	6.02e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HEKEIKFC_03111	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HEKEIKFC_03112	5.74e-168	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HEKEIKFC_03113	2.53e-242	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEKEIKFC_03114	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEKEIKFC_03115	6.52e-249	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HEKEIKFC_03116	6.35e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HEKEIKFC_03117	2.02e-248	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HEKEIKFC_03118	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HEKEIKFC_03119	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HEKEIKFC_03120	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEKEIKFC_03121	2.86e-113	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HEKEIKFC_03122	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEKEIKFC_03123	7.11e-95	ylxL	-	-	-	-	-	-	-
HEKEIKFC_03124	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HEKEIKFC_03125	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEKEIKFC_03126	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HEKEIKFC_03127	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEKEIKFC_03128	7.76e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEKEIKFC_03129	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HEKEIKFC_03130	7.68e-274	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEKEIKFC_03131	9.82e-298	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HEKEIKFC_03132	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEKEIKFC_03133	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEKEIKFC_03134	5.66e-106	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HEKEIKFC_03135	4.04e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HEKEIKFC_03136	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HEKEIKFC_03137	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HEKEIKFC_03138	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEKEIKFC_03139	3.88e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HEKEIKFC_03140	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEKEIKFC_03141	5.18e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEKEIKFC_03142	2.6e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HEKEIKFC_03143	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEKEIKFC_03144	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEKEIKFC_03145	1.02e-232	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HEKEIKFC_03146	2.51e-300	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HEKEIKFC_03147	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HEKEIKFC_03148	1.91e-205	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HEKEIKFC_03149	4.75e-138	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEKEIKFC_03150	4.97e-249	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEKEIKFC_03151	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEKEIKFC_03152	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEKEIKFC_03153	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEKEIKFC_03154	1.31e-165	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HEKEIKFC_03155	3.66e-41	-	-	-	S	-	-	-	YlzJ-like protein
HEKEIKFC_03156	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEKEIKFC_03157	4.48e-172	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_03158	9.04e-296	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_03159	9.88e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEKEIKFC_03160	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HEKEIKFC_03161	1.31e-305	albE	-	-	S	-	-	-	Peptidase M16
HEKEIKFC_03162	4.79e-309	ymfH	-	-	S	-	-	-	zinc protease
HEKEIKFC_03163	7.08e-165	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HEKEIKFC_03164	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HEKEIKFC_03165	3.82e-184	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HEKEIKFC_03166	5.76e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HEKEIKFC_03167	1.17e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEKEIKFC_03168	9.36e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HEKEIKFC_03169	2.51e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEKEIKFC_03170	1.34e-279	pbpX	-	-	V	-	-	-	Beta-lactamase
HEKEIKFC_03171	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HEKEIKFC_03172	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HEKEIKFC_03173	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HEKEIKFC_03174	6.82e-250	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HEKEIKFC_03175	8.29e-273	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEKEIKFC_03176	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEKEIKFC_03177	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HEKEIKFC_03178	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HEKEIKFC_03179	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEKEIKFC_03180	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEKEIKFC_03181	1.96e-49	-	-	-	L	-	-	-	Phage integrase family
HEKEIKFC_03182	7.44e-48	-	-	-	-	-	-	-	-
HEKEIKFC_03183	2.47e-59	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
HEKEIKFC_03184	2.11e-19	-	-	-	-	-	-	-	-
HEKEIKFC_03185	4.84e-52	-	-	-	-	-	-	-	-
HEKEIKFC_03194	1.87e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4917)
HEKEIKFC_03195	1.49e-11	-	-	-	-	-	-	-	-
HEKEIKFC_03196	0.0	-	-	-	S	-	-	-	Pfam Transposase IS66
HEKEIKFC_03197	0.0	-	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEKEIKFC_03199	0.000595	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEKEIKFC_03201	1.61e-122	-	-	-	S	-	-	-	Phage capsid family
HEKEIKFC_03202	1.45e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HEKEIKFC_03203	1.81e-152	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HEKEIKFC_03204	6.21e-183	-	-	-	S	-	-	-	TIGRFAM Phage
HEKEIKFC_03205	1.89e-114	res	-	-	L	-	-	-	Resolvase, N terminal domain
HEKEIKFC_03206	7.21e-14	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
HEKEIKFC_03208	9.47e-20	-	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_03210	2.96e-30	-	-	-	-	-	-	-	-
HEKEIKFC_03211	4.07e-08	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
HEKEIKFC_03213	4.37e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEKEIKFC_03216	7.68e-81	-	-	-	-	-	-	-	-
HEKEIKFC_03217	1.01e-47	-	-	-	-	-	-	-	-
HEKEIKFC_03218	1.4e-39	-	-	-	-	-	-	-	-
HEKEIKFC_03222	3.04e-275	-	-	-	-	-	-	-	-
HEKEIKFC_03229	3.28e-73	-	-	-	L	-	-	-	Arm DNA-binding domain
HEKEIKFC_03231	1.88e-186	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEKEIKFC_03232	9.96e-251	yubA	-	-	S	-	-	-	transporter activity
HEKEIKFC_03233	7.8e-237	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HEKEIKFC_03234	6.95e-127	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HEKEIKFC_03235	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEKEIKFC_03236	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEKEIKFC_03237	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEKEIKFC_03238	4.4e-316	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEKEIKFC_03239	2.59e-178	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HEKEIKFC_03240	9.36e-55	-	-	-	-	-	-	-	-
HEKEIKFC_03241	3.47e-243	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HEKEIKFC_03242	1.89e-98	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HEKEIKFC_03243	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEKEIKFC_03244	4.67e-296	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEKEIKFC_03245	1.67e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HEKEIKFC_03246	3.06e-23	-	-	-	-	-	-	-	-
HEKEIKFC_03247	3.47e-35	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HEKEIKFC_03248	2.8e-230	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HEKEIKFC_03249	1.17e-92	yugN	-	-	S	-	-	-	YugN-like family
HEKEIKFC_03251	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HEKEIKFC_03252	7.96e-133	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HEKEIKFC_03253	4.34e-152	ycaC	-	-	Q	-	-	-	Isochorismatase family
HEKEIKFC_03254	7.9e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HEKEIKFC_03255	6.7e-286	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HEKEIKFC_03256	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HEKEIKFC_03257	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HEKEIKFC_03258	1.68e-266	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HEKEIKFC_03259	3.75e-109	alaR	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_03260	4.03e-200	yugF	-	-	I	-	-	-	Hydrolase
HEKEIKFC_03261	1.22e-54	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HEKEIKFC_03262	2.73e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEKEIKFC_03263	1.81e-292	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_03264	1.62e-87	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HEKEIKFC_03265	3.22e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HEKEIKFC_03266	2.48e-245	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HEKEIKFC_03267	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HEKEIKFC_03268	2.62e-95	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03269	1.6e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HEKEIKFC_03270	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEKEIKFC_03271	5.63e-163	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HEKEIKFC_03272	4.98e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HEKEIKFC_03273	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_03274	3.86e-238	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEKEIKFC_03275	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEKEIKFC_03277	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEKEIKFC_03278	1.09e-90	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEKEIKFC_03279	1.47e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEKEIKFC_03280	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEKEIKFC_03281	1.23e-101	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEKEIKFC_03282	1.91e-52	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEKEIKFC_03283	4.2e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HEKEIKFC_03284	3.42e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HEKEIKFC_03285	8.07e-148	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEKEIKFC_03286	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_03288	1.7e-111	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Polyprenyl synthetase
HEKEIKFC_03289	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
HEKEIKFC_03290	1.04e-67	yuzC	-	-	-	-	-	-	-
HEKEIKFC_03291	6.86e-296	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HEKEIKFC_03292	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEKEIKFC_03293	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HEKEIKFC_03294	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HEKEIKFC_03295	5.46e-51	yueH	-	-	S	-	-	-	YueH-like protein
HEKEIKFC_03296	6.33e-46	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HEKEIKFC_03297	9.69e-239	yueF	-	-	S	-	-	-	transporter activity
HEKEIKFC_03298	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HEKEIKFC_03299	1.57e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HEKEIKFC_03300	9.31e-166	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEKEIKFC_03301	8.01e-102	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HEKEIKFC_03302	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HEKEIKFC_03303	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEKEIKFC_03304	7.95e-276	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HEKEIKFC_03305	5.28e-53	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HEKEIKFC_03306	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HEKEIKFC_03307	5.19e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
HEKEIKFC_03308	1.34e-259	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HEKEIKFC_03309	3.06e-171	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HEKEIKFC_03310	3.87e-46	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HEKEIKFC_03311	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_03312	3.37e-221	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HEKEIKFC_03313	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HEKEIKFC_03314	4.55e-285	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HEKEIKFC_03315	7.08e-171	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_03316	1.04e-210	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HEKEIKFC_03317	1.13e-155	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HEKEIKFC_03318	3.73e-131	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HEKEIKFC_03319	5.77e-276	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HEKEIKFC_03320	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEKEIKFC_03321	4.99e-101	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HEKEIKFC_03322	7.98e-150	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03323	8.54e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
HEKEIKFC_03324	1.39e-299	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEKEIKFC_03325	1.03e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HEKEIKFC_03327	1.91e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEKEIKFC_03328	5.68e-40	-	-	-	-	-	-	-	-
HEKEIKFC_03329	5.92e-93	-	-	-	CP	-	-	-	Membrane
HEKEIKFC_03330	1.38e-158	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEKEIKFC_03332	5.3e-44	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
HEKEIKFC_03334	7.08e-123	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HEKEIKFC_03335	9.01e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_03336	1.38e-82	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HEKEIKFC_03337	5.54e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEKEIKFC_03338	1.49e-273	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEKEIKFC_03339	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HEKEIKFC_03340	8.47e-266	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEKEIKFC_03341	3.29e-73	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03342	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HEKEIKFC_03343	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HEKEIKFC_03344	2.26e-215	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEKEIKFC_03345	2.3e-251	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEKEIKFC_03346	1.43e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HEKEIKFC_03347	1.55e-250	yutH	-	-	S	-	-	-	Spore coat protein
HEKEIKFC_03348	1.5e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HEKEIKFC_03349	4.31e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEKEIKFC_03350	1.55e-95	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HEKEIKFC_03351	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03352	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEKEIKFC_03353	1.66e-250	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HEKEIKFC_03354	3.21e-166	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HEKEIKFC_03355	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEKEIKFC_03356	3.01e-186	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEKEIKFC_03357	2.02e-214	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HEKEIKFC_03358	3.55e-79	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
HEKEIKFC_03359	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HEKEIKFC_03360	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HEKEIKFC_03362	6.41e-281	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HEKEIKFC_03363	7.53e-236	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEKEIKFC_03364	4.55e-40	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEKEIKFC_03365	3.68e-229	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
HEKEIKFC_03366	9.77e-257	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HEKEIKFC_03367	2.25e-287	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HEKEIKFC_03368	1.54e-222	ybaS	-	-	S	-	-	-	Na -dependent transporter
HEKEIKFC_03369	1.26e-146	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HEKEIKFC_03370	2.37e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_03371	3.63e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_03372	2.1e-220	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HEKEIKFC_03373	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HEKEIKFC_03374	3.7e-299	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03375	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HEKEIKFC_03376	9.72e-313	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HEKEIKFC_03377	3.54e-311	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_03378	9.86e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEKEIKFC_03379	3.68e-112	ybbJ	-	-	J	-	-	-	acetyltransferase
HEKEIKFC_03380	1.85e-99	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HEKEIKFC_03386	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEKEIKFC_03387	1.11e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEKEIKFC_03388	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEKEIKFC_03389	5.88e-290	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03390	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEKEIKFC_03391	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEKEIKFC_03392	5.87e-197	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HEKEIKFC_03393	2.02e-138	-	-	-	S	-	-	-	ABC-2 family transporter protein
HEKEIKFC_03394	1.07e-124	ybdN	-	-	-	-	-	-	-
HEKEIKFC_03395	3.7e-166	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HEKEIKFC_03396	2.54e-207	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
HEKEIKFC_03397	7.37e-136	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HEKEIKFC_03398	5.62e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEKEIKFC_03399	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEKEIKFC_03400	4.51e-117	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HEKEIKFC_03401	5e-132	-	-	-	T	-	-	-	Histidine kinase
HEKEIKFC_03402	1.24e-104	-	-	-	KT	-	-	-	helix_turn_helix, Lux Regulon
HEKEIKFC_03403	9.14e-172	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_03404	6.11e-184	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEKEIKFC_03405	1.89e-154	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEKEIKFC_03406	1.62e-19	-	-	-	-	-	-	-	-
HEKEIKFC_03407	1.97e-73	-	-	-	Q	-	-	-	Thioesterase domain
HEKEIKFC_03408	0.0	-	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
HEKEIKFC_03409	0.0	-	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
HEKEIKFC_03410	1.92e-150	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	PFAM Acyl transferase
HEKEIKFC_03411	0.0	-	-	-	Q	-	-	-	Beta-ketoacyl synthase
HEKEIKFC_03412	0.0	-	-	-	Q	-	-	-	Polyketide synthase modules and related proteins
HEKEIKFC_03413	1.45e-120	-	-	-	Q	-	-	-	Flavin containing amine oxidoreductase
HEKEIKFC_03414	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
HEKEIKFC_03415	6.02e-51	-	-	-	Q	-	-	-	Dimerisation domain
HEKEIKFC_03416	3.52e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
HEKEIKFC_03417	7.13e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HEKEIKFC_03418	7.51e-146	yqeB	-	-	-	-	-	-	-
HEKEIKFC_03419	7.84e-55	ybyB	-	-	-	-	-	-	-
HEKEIKFC_03420	0.0	ybeC	-	-	E	-	-	-	amino acid
HEKEIKFC_03421	5.43e-54	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HEKEIKFC_03422	3.73e-207	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HEKEIKFC_03423	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HEKEIKFC_03424	5.8e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HEKEIKFC_03425	3.34e-266	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HEKEIKFC_03427	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HEKEIKFC_03428	2.44e-45	-	-	-	-	-	-	-	-
HEKEIKFC_03429	1.69e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEKEIKFC_03430	6.1e-255	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HEKEIKFC_03431	7.96e-272	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEKEIKFC_03432	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEKEIKFC_03433	8.6e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HEKEIKFC_03434	3.05e-194	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HEKEIKFC_03435	2.13e-55	ybfN	-	-	-	-	-	-	-
HEKEIKFC_03436	5.76e-245	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HEKEIKFC_03437	8.22e-272	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEKEIKFC_03438	5.02e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HEKEIKFC_03439	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEKEIKFC_03440	1.02e-230	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HEKEIKFC_03441	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HEKEIKFC_03442	1.11e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEKEIKFC_03443	2.65e-280	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_03444	5.81e-221	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HEKEIKFC_03445	6.9e-35	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HEKEIKFC_03446	2.59e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEKEIKFC_03447	6.96e-145	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HEKEIKFC_03448	1.51e-235	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEKEIKFC_03449	9.37e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HEKEIKFC_03450	1.54e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
HEKEIKFC_03451	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HEKEIKFC_03452	1.05e-101	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HEKEIKFC_03453	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HEKEIKFC_03454	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEKEIKFC_03455	7.24e-155	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEKEIKFC_03456	8.1e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEKEIKFC_03457	3.71e-261	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HEKEIKFC_03458	1.61e-309	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HEKEIKFC_03459	2.19e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HEKEIKFC_03460	5.87e-256	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HEKEIKFC_03461	5.23e-144	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEKEIKFC_03462	4.81e-252	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HEKEIKFC_03463	1.54e-218	yccK	-	-	C	-	-	-	Aldo keto reductase
HEKEIKFC_03464	1.38e-227	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HEKEIKFC_03465	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEKEIKFC_03466	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEKEIKFC_03467	6.25e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HEKEIKFC_03468	8.19e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HEKEIKFC_03469	1.05e-179	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HEKEIKFC_03470	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEKEIKFC_03471	2.99e-213	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HEKEIKFC_03472	1.4e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEKEIKFC_03473	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEKEIKFC_03474	1.2e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEKEIKFC_03475	1.16e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HEKEIKFC_03476	3.63e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HEKEIKFC_03477	2.46e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HEKEIKFC_03478	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HEKEIKFC_03479	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HEKEIKFC_03480	3.34e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
HEKEIKFC_03481	6.36e-277	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HEKEIKFC_03482	1.28e-292	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HEKEIKFC_03483	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HEKEIKFC_03484	1.16e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HEKEIKFC_03485	3.61e-267	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HEKEIKFC_03486	1.48e-289	ycgA	-	-	S	-	-	-	Membrane
HEKEIKFC_03487	2.55e-105	ycgB	-	-	-	-	-	-	-
HEKEIKFC_03488	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HEKEIKFC_03489	1.14e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEKEIKFC_03490	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HEKEIKFC_03491	6.92e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEKEIKFC_03492	1.11e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HEKEIKFC_03493	6.95e-191	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HEKEIKFC_03494	4.47e-312	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEKEIKFC_03495	3.22e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HEKEIKFC_03496	7.44e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEKEIKFC_03497	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEKEIKFC_03498	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEKEIKFC_03499	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HEKEIKFC_03500	1.52e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEKEIKFC_03501	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HEKEIKFC_03502	8.12e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEKEIKFC_03503	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEKEIKFC_03504	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEKEIKFC_03505	2.12e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEKEIKFC_03506	4.45e-140	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HEKEIKFC_03507	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEKEIKFC_03508	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEKEIKFC_03509	2.29e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HEKEIKFC_03510	6.61e-195	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HEKEIKFC_03511	2.38e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HEKEIKFC_03512	1.43e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HEKEIKFC_03513	4.91e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HEKEIKFC_03514	1.67e-225	yyaD	-	-	S	-	-	-	Membrane
HEKEIKFC_03515	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03516	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEKEIKFC_03517	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEKEIKFC_03518	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HEKEIKFC_03519	4.77e-99	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEKEIKFC_03520	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEKEIKFC_03521	1.21e-134	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HEKEIKFC_03522	1.09e-124	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEKEIKFC_03523	7.45e-181	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HEKEIKFC_03524	1.9e-229	ccpB	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_03525	5.7e-87	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEKEIKFC_03526	7.51e-316	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HEKEIKFC_03527	5.73e-208	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEKEIKFC_03528	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HEKEIKFC_03529	2.32e-52	ebrA	-	-	U	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEKEIKFC_03530	2.01e-18	-	-	-	K	-	-	-	Transcriptional
HEKEIKFC_03531	1.76e-101	-	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_03532	2.9e-128	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEKEIKFC_03533	1.35e-166	-	-	-	EG	-	-	-	EamA-like transporter family
HEKEIKFC_03534	4.31e-316	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEKEIKFC_03535	1.93e-175	bdh	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEKEIKFC_03536	6.64e-208	-	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_03537	2.76e-86	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HEKEIKFC_03538	1.12e-209	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
HEKEIKFC_03539	3.12e-08	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HEKEIKFC_03540	1.85e-99	yybA	-	-	K	-	-	-	transcriptional
HEKEIKFC_03541	5.16e-192	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEKEIKFC_03542	6.79e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HEKEIKFC_03543	6.92e-148	ydgI	-	-	C	-	-	-	nitroreductase
HEKEIKFC_03544	1.94e-74	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HEKEIKFC_03545	3.78e-128	-	-	-	E	-	-	-	LysE type translocator
HEKEIKFC_03546	2.06e-202	-	-	-	K	-	-	-	LysR substrate binding domain
HEKEIKFC_03547	7.42e-201	-	-	-	G	-	-	-	Major Facilitator Superfamily
HEKEIKFC_03548	2.74e-117	-	-	-	S	-	-	-	PFAM DinB family protein
HEKEIKFC_03549	8.99e-148	-	-	-	K	-	-	-	FCD domain
HEKEIKFC_03550	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HEKEIKFC_03551	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HEKEIKFC_03552	3.96e-195	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEKEIKFC_03553	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HEKEIKFC_03554	1.08e-85	yybR	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_03555	2.25e-109	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HEKEIKFC_03557	2.38e-202	yybS	-	-	S	-	-	-	membrane
HEKEIKFC_03558	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HEKEIKFC_03559	1.58e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HEKEIKFC_03560	2.06e-158	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
HEKEIKFC_03561	2.15e-157	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HEKEIKFC_03562	1.18e-308	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HEKEIKFC_03563	8.59e-293	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
HEKEIKFC_03564	4.31e-257	-	-	-	S	-	-	-	Ecdysteroid kinase
HEKEIKFC_03565	2.14e-297	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HEKEIKFC_03566	1.03e-24	yycC	-	-	K	-	-	-	YycC-like protein
HEKEIKFC_03568	6.11e-36	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HEKEIKFC_03569	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HEKEIKFC_03570	1.29e-93	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEKEIKFC_03571	1.55e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEKEIKFC_03576	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_03577	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_03578	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03579	1.45e-196	yycI	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_03580	9.84e-192	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HEKEIKFC_03581	1.63e-278	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEKEIKFC_03582	9.23e-14	phoP1	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_03583	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEKEIKFC_03584	9e-241	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HEKEIKFC_03585	0.0	-	-	-	-	-	-	-	-
HEKEIKFC_03586	6.06e-257	-	-	-	S	-	-	-	Major Facilitator Superfamily
HEKEIKFC_03587	0.0	-	-	-	S	-	-	-	ABC transporter
HEKEIKFC_03588	1.3e-188	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HEKEIKFC_03589	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HEKEIKFC_03590	2.69e-57	sdpR	-	-	K	-	-	-	transcriptional
HEKEIKFC_03591	3.8e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HEKEIKFC_03592	6.81e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HEKEIKFC_03593	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEKEIKFC_03594	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HEKEIKFC_03595	1.61e-253	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HEKEIKFC_03597	6.61e-110	yycN	-	-	K	-	-	-	Acetyltransferase
HEKEIKFC_03598	3.7e-234	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HEKEIKFC_03599	7.96e-170	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEKEIKFC_03600	7.51e-278	yycP	-	-	-	-	-	-	-
HEKEIKFC_03604	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEKEIKFC_03605	1.61e-288	-	2.1.1.72	-	V	ko:K03427,ko:K07317	-	ko00000,ko01000,ko02048	N-6 DNA methylase
HEKEIKFC_03607	7.48e-90	radC	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HEKEIKFC_03608	4.19e-62	-	-	-	-	-	-	-	-
HEKEIKFC_03612	0.0	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
HEKEIKFC_03615	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HEKEIKFC_03618	5.62e-294	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEKEIKFC_03619	0.0	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HEKEIKFC_03621	9.83e-17	-	-	-	S	-	-	-	Restriction endonuclease
HEKEIKFC_03622	2.58e-141	-	-	-	D	-	-	-	AAA domain
HEKEIKFC_03623	7.34e-26	-	-	-	-	-	-	-	-
HEKEIKFC_03624	1.99e-237	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HEKEIKFC_03625	3.2e-241	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEKEIKFC_03626	3.33e-122	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HEKEIKFC_03627	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEKEIKFC_03628	2.23e-196	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HEKEIKFC_03629	6.43e-110	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HEKEIKFC_03630	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HEKEIKFC_03631	6.13e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HEKEIKFC_03632	2.78e-292	-	-	-	S	-	-	-	Fic/DOC family
HEKEIKFC_03633	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HEKEIKFC_03634	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HEKEIKFC_03635	1.34e-162	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
HEKEIKFC_03636	9.49e-98	yxaI	-	-	S	-	-	-	membrane protein domain
HEKEIKFC_03637	6.88e-259	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEKEIKFC_03638	7.01e-67	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEKEIKFC_03639	1.19e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HEKEIKFC_03640	4.97e-189	yxaL	-	-	S	-	-	-	PQQ-like domain
HEKEIKFC_03641	9.34e-317	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEKEIKFC_03642	5.65e-277	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEKEIKFC_03643	4.3e-256	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HEKEIKFC_03644	4.8e-254	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_03645	1.07e-131	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEKEIKFC_03646	8.74e-195	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEKEIKFC_03648	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HEKEIKFC_03649	1.1e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEKEIKFC_03650	1.88e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HEKEIKFC_03651	4.11e-129	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HEKEIKFC_03652	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEKEIKFC_03653	1.61e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEKEIKFC_03654	5.39e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEKEIKFC_03655	6.21e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEKEIKFC_03656	3.42e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HEKEIKFC_03657	4.07e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEKEIKFC_03658	3.4e-146	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEKEIKFC_03659	5.39e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEKEIKFC_03660	2.09e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEKEIKFC_03661	1.27e-160	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_03662	8.13e-156	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_03663	4.95e-170	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_03664	1.29e-156	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HEKEIKFC_03665	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HEKEIKFC_03666	2.97e-70	yvaP	-	-	K	-	-	-	transcriptional
HEKEIKFC_03667	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HEKEIKFC_03668	9.53e-93	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HEKEIKFC_03669	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
HEKEIKFC_03670	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HEKEIKFC_03671	1.7e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HEKEIKFC_03672	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEKEIKFC_03673	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HEKEIKFC_03675	9.79e-65	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HEKEIKFC_03676	3.94e-180	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_03677	3.98e-206	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HEKEIKFC_03678	3.16e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HEKEIKFC_03679	3.98e-166	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HEKEIKFC_03680	3.54e-188	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HEKEIKFC_03681	2.84e-154	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEKEIKFC_03682	3.35e-155	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEKEIKFC_03683	3.01e-179	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEKEIKFC_03684	3.04e-233	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEKEIKFC_03685	2.9e-61	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HEKEIKFC_03686	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEKEIKFC_03687	1.03e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEKEIKFC_03688	3.75e-244	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HEKEIKFC_03689	2.81e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HEKEIKFC_03690	3.24e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
HEKEIKFC_03691	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HEKEIKFC_03692	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HEKEIKFC_03693	1.76e-135	bdbD	-	-	O	-	-	-	Thioredoxin
HEKEIKFC_03694	3.05e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HEKEIKFC_03695	1.1e-189	-	-	-	S	-	-	-	Metallo-peptidase family M12
HEKEIKFC_03696	1.3e-138	yvgT	-	-	S	-	-	-	membrane
HEKEIKFC_03697	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEKEIKFC_03698	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEKEIKFC_03699	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HEKEIKFC_03700	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HEKEIKFC_03701	1.38e-113	yvgO	-	-	-	-	-	-	-
HEKEIKFC_03702	7.23e-200	yvgN	-	-	S	-	-	-	reductase
HEKEIKFC_03703	4.86e-260	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HEKEIKFC_03704	1.12e-244	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEKEIKFC_03705	1.42e-219	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HEKEIKFC_03706	8.62e-253	-	-	-	T	-	-	-	Histidine kinase
HEKEIKFC_03707	2.05e-146	yfiK	-	-	K	-	-	-	Regulator
HEKEIKFC_03708	1.57e-122	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HEKEIKFC_03709	1.95e-178	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HEKEIKFC_03710	4.72e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HEKEIKFC_03711	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HEKEIKFC_03712	8.3e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HEKEIKFC_03713	4.34e-19	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HEKEIKFC_03714	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HEKEIKFC_03715	4.15e-158	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HEKEIKFC_03716	2.21e-228	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEKEIKFC_03717	3.29e-238	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_03718	1.37e-225	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_03719	1.97e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEKEIKFC_03720	3.41e-88	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HEKEIKFC_03721	3.11e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HEKEIKFC_03722	3.78e-21	-	-	-	S	-	-	-	YvrJ protein family
HEKEIKFC_03723	3.23e-134	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HEKEIKFC_03724	3.96e-49	-	-	-	-	-	-	-	-
HEKEIKFC_03725	7.74e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_03726	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HEKEIKFC_03727	1.09e-218	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HEKEIKFC_03728	1.67e-178	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_03729	1.36e-214	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEKEIKFC_03730	1.38e-231	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEKEIKFC_03731	1.54e-288	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HEKEIKFC_03732	3.1e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HEKEIKFC_03733	5.58e-289	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_03734	1.62e-68	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HEKEIKFC_03735	3.96e-133	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HEKEIKFC_03736	2.03e-192	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HEKEIKFC_03737	8.92e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HEKEIKFC_03738	9.98e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_03739	2.91e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEKEIKFC_03740	1.36e-265	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HEKEIKFC_03741	2.52e-243	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HEKEIKFC_03742	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HEKEIKFC_03743	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HEKEIKFC_03744	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEKEIKFC_03745	3.11e-201	yuxN	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_03746	4.63e-33	-	-	-	-	-	-	-	-
HEKEIKFC_03747	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEKEIKFC_03748	3.17e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_03749	1.95e-307	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEKEIKFC_03750	4.12e-103	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HEKEIKFC_03751	4.68e-198	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_03752	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HEKEIKFC_03753	2.66e-60	-	-	-	S	-	-	-	YusW-like protein
HEKEIKFC_03754	1.29e-192	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEKEIKFC_03755	2.15e-52	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HEKEIKFC_03756	4.9e-240	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEKEIKFC_03757	3.69e-179	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HEKEIKFC_03758	1.52e-206	-	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_03759	2.44e-206	yusT	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HEKEIKFC_03760	5.19e-169	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEKEIKFC_03761	1.69e-86	yusQ	-	-	S	-	-	-	Tautomerase enzyme
HEKEIKFC_03762	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HEKEIKFC_03763	9.65e-92	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HEKEIKFC_03764	4.46e-72	yusN	-	-	M	-	-	-	Coat F domain
HEKEIKFC_03765	3.2e-58	-	-	-	-	-	-	-	-
HEKEIKFC_03766	2.1e-263	yusP	-	-	P	-	-	-	Major facilitator superfamily
HEKEIKFC_03767	1.31e-215	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HEKEIKFC_03768	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HEKEIKFC_03769	9.03e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HEKEIKFC_03770	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HEKEIKFC_03771	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HEKEIKFC_03772	4.16e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HEKEIKFC_03773	5.16e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HEKEIKFC_03774	1.08e-82	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HEKEIKFC_03775	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
HEKEIKFC_03776	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HEKEIKFC_03777	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEKEIKFC_03778	1.46e-138	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HEKEIKFC_03779	4.46e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HEKEIKFC_03780	8.85e-85	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEKEIKFC_03781	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEKEIKFC_03782	1.23e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HEKEIKFC_03783	2.31e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEKEIKFC_03784	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HEKEIKFC_03785	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HEKEIKFC_03786	5.94e-200	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HEKEIKFC_03787	2.82e-100	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HEKEIKFC_03788	7.31e-164	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HEKEIKFC_03789	8.71e-258	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HEKEIKFC_03790	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HEKEIKFC_03793	1.65e-212	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEKEIKFC_03794	2.33e-238	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HEKEIKFC_03795	2.12e-312	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HEKEIKFC_03796	5.26e-203	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEKEIKFC_03797	3.6e-209	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HEKEIKFC_03798	1.52e-205	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HEKEIKFC_03799	5.89e-173	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HEKEIKFC_03800	1.58e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_03801	7.06e-218	bsn	-	-	L	-	-	-	Ribonuclease
HEKEIKFC_03802	1.77e-301	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEKEIKFC_03803	5.95e-302	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HEKEIKFC_03804	3.01e-274	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_03805	5.84e-83	-	-	-	-	-	-	-	-
HEKEIKFC_03807	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEKEIKFC_03808	3.41e-161	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HEKEIKFC_03809	3.54e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HEKEIKFC_03810	6.3e-91	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HEKEIKFC_03811	9.64e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEKEIKFC_03812	4.55e-137	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HEKEIKFC_03813	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEKEIKFC_03814	4.99e-150	yhcQ	-	-	M	-	-	-	Spore coat protein
HEKEIKFC_03815	1.12e-205	yhcP	-	-	-	-	-	-	-
HEKEIKFC_03816	2.69e-122	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEKEIKFC_03817	3.29e-68	yhcM	-	-	-	-	-	-	-
HEKEIKFC_03818	2.02e-305	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEKEIKFC_03819	1.43e-234	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HEKEIKFC_03820	6.29e-185	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HEKEIKFC_03821	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HEKEIKFC_03822	6.38e-209	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEKEIKFC_03823	1.93e-214	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_03824	1.03e-161	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_03825	1.07e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HEKEIKFC_03826	1.33e-65	-	-	-	-	-	-	-	-
HEKEIKFC_03827	1.41e-72	yhcC	-	-	-	-	-	-	-
HEKEIKFC_03828	9.09e-129	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HEKEIKFC_03829	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HEKEIKFC_03830	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HEKEIKFC_03831	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HEKEIKFC_03832	1.02e-279	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HEKEIKFC_03833	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HEKEIKFC_03834	1.23e-07	-	-	-	-	-	-	-	-
HEKEIKFC_03835	2.02e-94	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HEKEIKFC_03836	1.62e-84	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HEKEIKFC_03837	1.39e-140	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HEKEIKFC_03838	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEKEIKFC_03839	2.13e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
HEKEIKFC_03840	3.44e-286	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEKEIKFC_03841	4.53e-146	yhzB	-	-	S	-	-	-	B3/4 domain
HEKEIKFC_03843	5.25e-106	ygaO	-	-	-	-	-	-	-
HEKEIKFC_03844	1.38e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEKEIKFC_03845	8.61e-273	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HEKEIKFC_03846	2.37e-185	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEKEIKFC_03847	2.49e-229	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HEKEIKFC_03848	5.25e-179	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HEKEIKFC_03849	1.16e-222	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HEKEIKFC_03850	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEKEIKFC_03851	3.29e-168	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_03852	1.15e-171	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_03853	4.37e-162	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEKEIKFC_03854	4.08e-179	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEKEIKFC_03855	1.56e-291	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
HEKEIKFC_03857	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
HEKEIKFC_03858	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEKEIKFC_03859	4.02e-171	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HEKEIKFC_03860	2.21e-144	-	-	-	C	-	-	-	Na+/H+ antiporter family
HEKEIKFC_03863	2.51e-86	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	Ami_2
HEKEIKFC_03864	2.01e-79	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
HEKEIKFC_03865	9.5e-08	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
HEKEIKFC_03867	7.25e-219	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEKEIKFC_03868	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
HEKEIKFC_03869	9.69e-124	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HEKEIKFC_03871	1.35e-167	-	-	-	D	-	-	-	phage tail tape measure protein
HEKEIKFC_03873	0.000258	-	-	-	-	-	-	-	-
HEKEIKFC_03874	8.37e-21	-	-	-	N	-	-	-	Maj_tail_phi13 phage major tail , phi13 family protein
HEKEIKFC_03875	3.28e-13	-	-	-	S	-	-	-	TIGRFAM phage protein, HK97 gp10 family
HEKEIKFC_03877	3.54e-30	-	-	-	S	-	-	-	head-tail adaptor
HEKEIKFC_03878	2.88e-29	-	-	-	-	-	-	-	-
HEKEIKFC_03879	1.81e-05	-	-	-	-	-	-	-	-
HEKEIKFC_03880	7.44e-187	-	-	-	S	-	-	-	Phage capsid family
HEKEIKFC_03881	9.66e-110	-	-	-	OU	-	-	-	Clp protease
HEKEIKFC_03882	1.71e-227	-	-	-	S	-	-	-	Phage portal protein
HEKEIKFC_03883	0.0	-	-	-	L	-	-	-	Phage Terminase
HEKEIKFC_03884	2.13e-58	-	-	-	-	-	-	-	-
HEKEIKFC_03885	8.97e-22	-	-	-	V	-	-	-	HNH endonuclease
HEKEIKFC_03889	2.64e-93	-	-	-	L	-	-	-	Phage integrase family
HEKEIKFC_03890	2.67e-69	-	-	-	M	-	-	-	ArpU family transcriptional regulator
HEKEIKFC_03891	1.73e-08	-	-	-	-	-	-	-	-
HEKEIKFC_03896	1.07e-09	-	-	-	S	-	-	-	YopX protein
HEKEIKFC_03902	8.27e-83	-	-	-	-	-	-	-	-
HEKEIKFC_03906	6.47e-21	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HEKEIKFC_03907	1.09e-05	-	-	-	-	-	-	-	-
HEKEIKFC_03909	8.4e-36	-	-	-	-	-	-	-	-
HEKEIKFC_03910	1.46e-08	-	-	-	-	-	-	-	-
HEKEIKFC_03912	7.62e-23	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HEKEIKFC_03913	2.09e-99	-	-	-	L	-	-	-	dnaD_dom DnaD domain protein
HEKEIKFC_03915	6.41e-50	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HEKEIKFC_03916	7.47e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEKEIKFC_03917	1.7e-32	-	-	-	K	-	-	-	Transcriptional
HEKEIKFC_03920	4.73e-93	-	-	-	-	-	-	-	-
HEKEIKFC_03921	1.07e-169	-	-	-	L	-	-	-	Phage integrase family
HEKEIKFC_03933	0.000445	-	-	-	V	-	-	-	Protein of unknown function DUF262
HEKEIKFC_03936	1.41e-36	-	-	-	-	-	-	-	-
HEKEIKFC_03939	1.74e-94	-	-	-	M	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEKEIKFC_03940	1.43e-215	traE	-	-	U	-	-	-	Psort location Cytoplasmic, score
HEKEIKFC_03941	7.82e-77	-	-	-	-	-	-	-	-
HEKEIKFC_03945	5.85e-131	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
HEKEIKFC_03948	1.37e-15	-	-	-	-	-	-	-	-
HEKEIKFC_03950	1.35e-100	traA	-	-	L	-	-	-	MobA MobL family protein
HEKEIKFC_03951	5.19e-134	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG3505 Type IV secretory pathway, VirD4 components
HEKEIKFC_03952	1.53e-237	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
HEKEIKFC_03955	4.87e-81	-	-	-	E	-	-	-	Zn peptidase
HEKEIKFC_03965	1.09e-21	-	-	-	-	-	-	-	-
HEKEIKFC_03966	1.96e-51	-	-	-	-	-	-	-	-
HEKEIKFC_03967	7.71e-13	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HEKEIKFC_03971	1.05e-35	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Cysteine protease
HEKEIKFC_03974	1.18e-84	-	-	-	N	-	-	-	domain, Protein
HEKEIKFC_03976	1.02e-49	-	-	-	U	-	-	-	Flp pilus assembly protein RcpC/CpaB
HEKEIKFC_03978	5.2e-12	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT
HEKEIKFC_03987	5.1e-122	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
HEKEIKFC_03988	2.86e-93	-	-	-	-	-	-	-	-
HEKEIKFC_03990	1.48e-156	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
HEKEIKFC_03991	4.52e-59	-	-	-	-	-	-	-	-
HEKEIKFC_03992	7.99e-20	-	-	-	-	-	-	-	-
HEKEIKFC_03996	7.65e-86	res	-	-	L	-	-	-	Resolvase, N terminal domain
HEKEIKFC_04003	8.71e-52	yjqA	-	-	S	-	-	-	Bacterial PH domain
HEKEIKFC_04007	2.48e-28	-	-	-	-	-	-	-	-
HEKEIKFC_04012	1.41e-08	-	-	-	-	-	-	-	-
HEKEIKFC_04014	6.79e-105	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEKEIKFC_04022	1.37e-70	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HEKEIKFC_04025	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HEKEIKFC_04026	1.14e-83	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HEKEIKFC_04027	1.63e-258	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HEKEIKFC_04028	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HEKEIKFC_04029	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEKEIKFC_04030	3.12e-250	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEKEIKFC_04031	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HEKEIKFC_04032	1.23e-160	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEKEIKFC_04033	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEKEIKFC_04034	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEKEIKFC_04035	3.16e-151	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HEKEIKFC_04036	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HEKEIKFC_04037	4.11e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEKEIKFC_04038	1.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEKEIKFC_04039	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HEKEIKFC_04040	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HEKEIKFC_04041	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEKEIKFC_04042	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HEKEIKFC_04043	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEKEIKFC_04044	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEKEIKFC_04045	2.33e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEKEIKFC_04046	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEKEIKFC_04047	7.25e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HEKEIKFC_04048	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEKEIKFC_04049	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEKEIKFC_04050	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HEKEIKFC_04051	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEKEIKFC_04052	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEKEIKFC_04053	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEKEIKFC_04054	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEKEIKFC_04055	8.14e-240	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HEKEIKFC_04056	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HEKEIKFC_04057	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEKEIKFC_04058	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HEKEIKFC_04059	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEKEIKFC_04060	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEKEIKFC_04061	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEKEIKFC_04062	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEKEIKFC_04063	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEKEIKFC_04064	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEKEIKFC_04065	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HEKEIKFC_04066	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEKEIKFC_04067	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEKEIKFC_04068	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEKEIKFC_04069	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEKEIKFC_04070	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEKEIKFC_04071	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEKEIKFC_04072	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEKEIKFC_04073	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEKEIKFC_04074	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEKEIKFC_04075	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HEKEIKFC_04076	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HEKEIKFC_04077	7.75e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEKEIKFC_04078	1.46e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEKEIKFC_04079	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HEKEIKFC_04080	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEKEIKFC_04081	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HEKEIKFC_04082	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEKEIKFC_04083	2.28e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEKEIKFC_04084	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEKEIKFC_04085	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HEKEIKFC_04086	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEKEIKFC_04087	4.91e-190	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEKEIKFC_04088	1.13e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEKEIKFC_04089	8.74e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEKEIKFC_04090	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEKEIKFC_04091	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HEKEIKFC_04092	7.18e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HEKEIKFC_04093	1.06e-106	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
HEKEIKFC_04094	1.08e-101	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HEKEIKFC_04095	1.98e-173	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEKEIKFC_04096	2.21e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEKEIKFC_04097	6.81e-103	gerD	-	-	-	ko:K06294	-	ko00000	-
HEKEIKFC_04098	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HEKEIKFC_04099	9.06e-183	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HEKEIKFC_04100	5.18e-30	-	-	-	-	-	-	-	-
HEKEIKFC_04102	5.37e-251	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
HEKEIKFC_04106	5.58e-59	-	-	-	-	-	-	-	-
HEKEIKFC_04108	3.03e-62	-	-	-	-	-	-	-	-
HEKEIKFC_04109	8.52e-34	-	-	-	S	-	-	-	YolD-like protein
HEKEIKFC_04110	1.18e-72	-	-	-	-	-	-	-	-
HEKEIKFC_04111	7.51e-41	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HEKEIKFC_04112	3.68e-23	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	Belongs to the WXG100 family
HEKEIKFC_04113	3.43e-106	-	-	-	-	-	-	-	-
HEKEIKFC_04115	9.4e-165	-	-	-	-	-	-	-	-
HEKEIKFC_04118	8.7e-65	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HEKEIKFC_04119	1.88e-95	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
HEKEIKFC_04121	8.5e-213	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HEKEIKFC_04122	4.44e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HEKEIKFC_04123	1.76e-185	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
HEKEIKFC_04124	8.64e-104	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
HEKEIKFC_04125	3.68e-107	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEKEIKFC_04126	1.14e-282	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HEKEIKFC_04127	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HEKEIKFC_04128	3.61e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEKEIKFC_04129	1.1e-276	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEKEIKFC_04130	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEKEIKFC_04131	8.91e-67	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEKEIKFC_04132	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEKEIKFC_04133	5.89e-179	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEKEIKFC_04134	2.06e-161	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HEKEIKFC_04137	2.48e-136	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HEKEIKFC_04139	1.91e-31	yjfB	-	-	S	-	-	-	Putative motility protein
HEKEIKFC_04140	6.26e-92	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HEKEIKFC_04141	3.5e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HEKEIKFC_04142	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HEKEIKFC_04143	2.2e-117	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEKEIKFC_04144	2.28e-291	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEKEIKFC_04145	2.43e-285	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEKEIKFC_04146	1e-39	-	-	-	-	-	-	-	-
HEKEIKFC_04147	1.95e-185	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HEKEIKFC_04148	2.79e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HEKEIKFC_04149	1.86e-167	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEKEIKFC_04150	5.01e-228	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HEKEIKFC_04151	2.1e-119	yjlB	-	-	S	-	-	-	Cupin domain
HEKEIKFC_04152	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEKEIKFC_04153	7.49e-281	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEKEIKFC_04154	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HEKEIKFC_04155	0.0	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HEKEIKFC_04156	1.24e-235	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HEKEIKFC_04157	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HEKEIKFC_04158	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HEKEIKFC_04159	7.44e-112	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEKEIKFC_04160	9.87e-167	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEKEIKFC_04161	1.3e-19	-	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_04163	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HEKEIKFC_04164	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEKEIKFC_04165	6.1e-40	yazB	-	-	K	-	-	-	transcriptional
HEKEIKFC_04166	8.2e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEKEIKFC_04167	1.13e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEKEIKFC_04168	2.24e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEKEIKFC_04169	1.71e-207	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HEKEIKFC_04170	5.35e-139	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HEKEIKFC_04171	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEKEIKFC_04172	8.88e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEKEIKFC_04173	1.02e-200	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HEKEIKFC_04174	1.85e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEKEIKFC_04175	6.64e-187	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEKEIKFC_04176	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEKEIKFC_04177	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HEKEIKFC_04178	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEKEIKFC_04179	1.34e-235	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HEKEIKFC_04180	2.19e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEKEIKFC_04181	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HEKEIKFC_04184	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HEKEIKFC_04185	1.2e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HEKEIKFC_04186	1.18e-134	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HEKEIKFC_04187	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HEKEIKFC_04188	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEKEIKFC_04189	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEKEIKFC_04190	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEKEIKFC_04191	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HEKEIKFC_04192	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEKEIKFC_04193	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HEKEIKFC_04194	2.89e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEKEIKFC_04195	6.18e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEKEIKFC_04196	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEKEIKFC_04197	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEKEIKFC_04198	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HEKEIKFC_04199	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HEKEIKFC_04200	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HEKEIKFC_04201	5.51e-206	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEKEIKFC_04202	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HEKEIKFC_04203	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_04204	1.41e-209	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HEKEIKFC_04205	8.41e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEKEIKFC_04206	7.62e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEKEIKFC_04207	2.49e-310	yabE	-	-	T	-	-	-	protein conserved in bacteria
HEKEIKFC_04208	4.31e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HEKEIKFC_04209	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEKEIKFC_04210	1.76e-57	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HEKEIKFC_04211	8.18e-210	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEKEIKFC_04212	6.96e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HEKEIKFC_04213	3.99e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HEKEIKFC_04214	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HEKEIKFC_04215	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HEKEIKFC_04216	3.29e-234	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HEKEIKFC_04217	2.98e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HEKEIKFC_04218	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_04219	7.75e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEKEIKFC_04220	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HEKEIKFC_04221	5.11e-246	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HEKEIKFC_04222	6.9e-135	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEKEIKFC_04223	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HEKEIKFC_04224	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HEKEIKFC_04225	2.68e-173	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_04226	3.11e-215	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HEKEIKFC_04227	5.25e-166	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEKEIKFC_04228	1.36e-287	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HEKEIKFC_04229	1.22e-160	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_04230	5.2e-209	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HEKEIKFC_04231	2.8e-230	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_04232	1.66e-222	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEKEIKFC_04233	2.08e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEKEIKFC_04234	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HEKEIKFC_04235	7.09e-53	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HEKEIKFC_04236	1.13e-249	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEKEIKFC_04237	0.0	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEKEIKFC_04238	5.76e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HEKEIKFC_04239	3.1e-137	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HEKEIKFC_04241	3.66e-185	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
HEKEIKFC_04242	2.35e-270	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HEKEIKFC_04243	6.95e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HEKEIKFC_04244	4.06e-84	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEKEIKFC_04245	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEKEIKFC_04246	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HEKEIKFC_04247	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEKEIKFC_04248	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEKEIKFC_04249	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HEKEIKFC_04250	1.11e-189	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEKEIKFC_04251	1.25e-236	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HEKEIKFC_04252	6.12e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEKEIKFC_04253	7.52e-174	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEKEIKFC_04254	1.01e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HEKEIKFC_04255	3.51e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HEKEIKFC_04256	3e-98	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HEKEIKFC_04258	1.48e-99	ytkA	-	-	S	-	-	-	YtkA-like
HEKEIKFC_04259	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEKEIKFC_04260	6.93e-53	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HEKEIKFC_04261	9.31e-137	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HEKEIKFC_04262	7.13e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HEKEIKFC_04263	4.48e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HEKEIKFC_04264	8.62e-233	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HEKEIKFC_04265	3.2e-33	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HEKEIKFC_04266	4.98e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEKEIKFC_04267	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEKEIKFC_04268	6.18e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEKEIKFC_04269	3.06e-196	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEKEIKFC_04270	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEKEIKFC_04271	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HEKEIKFC_04272	2.04e-167	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HEKEIKFC_04273	2.13e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HEKEIKFC_04295	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HEKEIKFC_04296	1.94e-288	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HEKEIKFC_04297	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HEKEIKFC_04298	6.78e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HEKEIKFC_04299	1.08e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HEKEIKFC_04300	5.07e-62	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HEKEIKFC_04301	1.97e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEKEIKFC_04302	3.34e-80	yqfX	-	-	S	-	-	-	membrane
HEKEIKFC_04303	2.88e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HEKEIKFC_04304	2.25e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HEKEIKFC_04305	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEKEIKFC_04306	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HEKEIKFC_04307	1.72e-213	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEKEIKFC_04308	6.06e-308	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEKEIKFC_04309	3.93e-87	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HEKEIKFC_04310	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEKEIKFC_04311	2.18e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEKEIKFC_04312	2.85e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HEKEIKFC_04313	9.68e-83	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HEKEIKFC_04314	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEKEIKFC_04315	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEKEIKFC_04316	1.36e-112	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HEKEIKFC_04317	2.22e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEKEIKFC_04318	5.89e-145	ccpN	-	-	K	-	-	-	CBS domain
HEKEIKFC_04319	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HEKEIKFC_04320	5.19e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HEKEIKFC_04321	8.73e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HEKEIKFC_04322	6e-24	-	-	-	S	-	-	-	YqzL-like protein
HEKEIKFC_04323	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEKEIKFC_04324	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEKEIKFC_04325	5.28e-83	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HEKEIKFC_04326	7.14e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEKEIKFC_04327	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HEKEIKFC_04328	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HEKEIKFC_04329	1.3e-282	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HEKEIKFC_04330	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HEKEIKFC_04331	1.04e-84	yqfB	-	-	-	-	-	-	-
HEKEIKFC_04332	4.48e-189	yqfA	-	-	S	-	-	-	UPF0365 protein
HEKEIKFC_04333	2.7e-295	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HEKEIKFC_04334	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HEKEIKFC_04335	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HEKEIKFC_04336	3.23e-200	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HEKEIKFC_04337	3.05e-298	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEKEIKFC_04338	1.06e-128	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HEKEIKFC_04339	9.97e-103	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HEKEIKFC_04340	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HEKEIKFC_04341	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HEKEIKFC_04342	4.02e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HEKEIKFC_04343	9.19e-137	ypjA	-	-	S	-	-	-	membrane
HEKEIKFC_04344	2.05e-182	ypjB	-	-	S	-	-	-	sporulation protein
HEKEIKFC_04345	1.42e-289	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HEKEIKFC_04346	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEKEIKFC_04347	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HEKEIKFC_04348	1.39e-188	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEKEIKFC_04349	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HEKEIKFC_04350	1.23e-167	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HEKEIKFC_04351	1.04e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HEKEIKFC_04352	1.98e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEKEIKFC_04353	9.42e-232	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEKEIKFC_04354	9.39e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HEKEIKFC_04355	5.71e-202	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEKEIKFC_04356	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEKEIKFC_04357	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HEKEIKFC_04358	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HEKEIKFC_04359	9.65e-105	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HEKEIKFC_04360	4.19e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HEKEIKFC_04361	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HEKEIKFC_04362	1.39e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HEKEIKFC_04363	1.02e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEKEIKFC_04364	2.11e-118	ypoC	-	-	-	-	-	-	-
HEKEIKFC_04365	4.43e-89	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HEKEIKFC_04366	8.24e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
HEKEIKFC_04367	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEKEIKFC_04368	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEKEIKFC_04369	2.61e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEKEIKFC_04370	2.86e-139	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEKEIKFC_04371	1.59e-285	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEKEIKFC_04372	2.41e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HEKEIKFC_04374	7.51e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HEKEIKFC_04375	4.04e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HEKEIKFC_04376	1.75e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HEKEIKFC_04377	5.85e-128	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HEKEIKFC_04378	2.89e-110	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEKEIKFC_04379	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEKEIKFC_04380	2.41e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEKEIKFC_04381	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEKEIKFC_04382	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HEKEIKFC_04383	6.44e-50	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HEKEIKFC_04387	6.45e-70	yjcN	-	-	-	-	-	-	-
HEKEIKFC_04388	5.51e-159	-	-	-	G	-	-	-	Cupin
HEKEIKFC_04389	5.93e-282	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEKEIKFC_04390	2.58e-191	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEKEIKFC_04391	3.04e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HEKEIKFC_04392	2.03e-122	yuaB	-	-	-	-	-	-	-
HEKEIKFC_04393	2.89e-124	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HEKEIKFC_04394	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEKEIKFC_04395	1.43e-289	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HEKEIKFC_04396	6.79e-141	-	-	-	S	-	-	-	MOSC domain
HEKEIKFC_04397	8.91e-106	yuaE	-	-	S	-	-	-	DinB superfamily
HEKEIKFC_04398	5.61e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HEKEIKFC_04399	6.2e-277	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HEKEIKFC_04400	1.99e-124	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HEKEIKFC_04401	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_04402	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEKEIKFC_04404	1.56e-142	rapE	-	-	S	ko:K06363	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HEKEIKFC_04406	1.8e-99	-	-	-	K	-	-	-	Transcriptional regulator
HEKEIKFC_04407	9.67e-211	pre	-	-	D	-	-	-	plasmid recombination enzyme
HEKEIKFC_04410	1.62e-217	-	-	-	L	-	-	-	Replication protein
HEKEIKFC_04411	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEKEIKFC_04412	2.8e-255	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HEKEIKFC_04413	1.36e-95	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HEKEIKFC_04414	1.68e-78	ylbA	-	-	S	-	-	-	YugN-like family
HEKEIKFC_04415	7.27e-252	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
HEKEIKFC_04430	2.36e-153	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HEKEIKFC_04431	2.48e-69	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
HEKEIKFC_04432	2.04e-66	-	-	-	L	-	-	-	transposase activity