ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
ICLPFEEK_00017 0.0 - - - C - - - Na+/H+ antiporter family
ICLPFEEK_00018 2.07e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
ICLPFEEK_00019 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ICLPFEEK_00020 0.0 ygaK - - C - - - Berberine and berberine like
ICLPFEEK_00023 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
ICLPFEEK_00024 2.52e-238 - - - S ko:K07045 - ko00000 Amidohydrolase
ICLPFEEK_00025 1.1e-180 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
ICLPFEEK_00026 4.48e-232 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
ICLPFEEK_00027 3.01e-188 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
ICLPFEEK_00028 7.7e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
ICLPFEEK_00029 1.18e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICLPFEEK_00030 3.16e-107 ygaO - - - - - - -
ICLPFEEK_00031 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00033 1.64e-148 yhzB - - S - - - B3/4 domain
ICLPFEEK_00034 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICLPFEEK_00035 2.13e-226 yhbB - - S - - - Putative amidase domain
ICLPFEEK_00036 8.36e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ICLPFEEK_00037 3.4e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
ICLPFEEK_00038 1.49e-87 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
ICLPFEEK_00039 2.47e-95 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
ICLPFEEK_00040 1.23e-07 - - - - - - - -
ICLPFEEK_00041 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
ICLPFEEK_00042 4.34e-281 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
ICLPFEEK_00043 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
ICLPFEEK_00044 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
ICLPFEEK_00045 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
ICLPFEEK_00046 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
ICLPFEEK_00047 1.41e-72 yhcC - - - - - - -
ICLPFEEK_00048 2.33e-66 - - - - - - - -
ICLPFEEK_00049 1.64e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00050 6.21e-163 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_00051 2.35e-215 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_00052 3.3e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ICLPFEEK_00053 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
ICLPFEEK_00054 2.13e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
ICLPFEEK_00055 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
ICLPFEEK_00056 9.51e-296 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICLPFEEK_00057 1.43e-82 yhcM - - - - - - -
ICLPFEEK_00058 2.3e-123 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICLPFEEK_00059 1.72e-209 yhcP - - - - - - -
ICLPFEEK_00060 8.36e-154 yhcQ - - M - - - Spore coat protein
ICLPFEEK_00061 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
ICLPFEEK_00062 8.19e-140 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
ICLPFEEK_00063 5.19e-222 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
ICLPFEEK_00064 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
ICLPFEEK_00065 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
ICLPFEEK_00066 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
ICLPFEEK_00067 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ICLPFEEK_00068 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICLPFEEK_00069 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ICLPFEEK_00070 2.83e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
ICLPFEEK_00071 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICLPFEEK_00072 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ICLPFEEK_00073 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
ICLPFEEK_00074 2.18e-267 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_00075 3.15e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICLPFEEK_00076 1.76e-118 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
ICLPFEEK_00077 6.98e-53 yhdB - - S - - - YhdB-like protein
ICLPFEEK_00078 1.46e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
ICLPFEEK_00079 1.27e-298 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
ICLPFEEK_00080 3.25e-97 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
ICLPFEEK_00081 0.0 ygxB - - M - - - Conserved TM helix
ICLPFEEK_00082 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
ICLPFEEK_00083 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
ICLPFEEK_00084 5.53e-178 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
ICLPFEEK_00085 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00086 5.96e-264 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
ICLPFEEK_00087 2.73e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_00088 8.9e-317 yhdG - - E ko:K03294 - ko00000 amino acid
ICLPFEEK_00089 1.78e-268 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
ICLPFEEK_00090 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
ICLPFEEK_00091 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
ICLPFEEK_00092 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
ICLPFEEK_00093 1.59e-142 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ICLPFEEK_00094 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
ICLPFEEK_00095 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
ICLPFEEK_00096 1.47e-288 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
ICLPFEEK_00097 2.84e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICLPFEEK_00098 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
ICLPFEEK_00099 2.12e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICLPFEEK_00100 4.27e-89 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICLPFEEK_00101 1.97e-169 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
ICLPFEEK_00102 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
ICLPFEEK_00103 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
ICLPFEEK_00104 7.18e-181 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
ICLPFEEK_00105 1.46e-202 nodB1 - - G - - - deacetylase
ICLPFEEK_00106 1.24e-199 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
ICLPFEEK_00107 1.22e-114 pksA - - K - - - Transcriptional regulator
ICLPFEEK_00108 2.29e-125 ymcC - - S - - - Membrane
ICLPFEEK_00109 4.31e-111 - - - T - - - universal stress protein
ICLPFEEK_00111 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
ICLPFEEK_00112 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
ICLPFEEK_00113 6.96e-145 yheG - - GM - - - NAD(P)H-binding
ICLPFEEK_00115 1.15e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
ICLPFEEK_00116 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
ICLPFEEK_00117 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
ICLPFEEK_00118 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
ICLPFEEK_00119 2.01e-266 yheB - - S - - - Belongs to the UPF0754 family
ICLPFEEK_00120 9.85e-72 yheA - - S - - - Belongs to the UPF0342 family
ICLPFEEK_00121 1.82e-260 yhaZ - - L - - - DNA alkylation repair enzyme
ICLPFEEK_00122 1.03e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
ICLPFEEK_00123 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
ICLPFEEK_00124 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
ICLPFEEK_00125 2.43e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
ICLPFEEK_00126 4.58e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
ICLPFEEK_00128 6.34e-179 yhaR - - I - - - enoyl-CoA hydratase
ICLPFEEK_00129 5.99e-21 - - - S - - - YhzD-like protein
ICLPFEEK_00130 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_00131 3.55e-279 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
ICLPFEEK_00132 3.17e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
ICLPFEEK_00133 0.0 yhaN - - L - - - AAA domain
ICLPFEEK_00134 4.29e-227 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
ICLPFEEK_00135 3.48e-44 yhaL - - S - - - Sporulation protein YhaL
ICLPFEEK_00136 5.57e-187 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ICLPFEEK_00137 1.29e-123 yhaK - - S - - - Putative zincin peptidase
ICLPFEEK_00138 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
ICLPFEEK_00139 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
ICLPFEEK_00140 4.74e-55 yhaH - - S - - - YtxH-like protein
ICLPFEEK_00141 2.55e-24 - - - - - - - -
ICLPFEEK_00142 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
ICLPFEEK_00143 5.28e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICLPFEEK_00144 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
ICLPFEEK_00145 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
ICLPFEEK_00146 7.81e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
ICLPFEEK_00147 6.35e-164 ecsC - - S - - - EcsC protein family
ICLPFEEK_00148 2.26e-288 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
ICLPFEEK_00149 4.16e-313 yhfA - - C - - - membrane
ICLPFEEK_00150 4.58e-119 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
ICLPFEEK_00151 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
ICLPFEEK_00152 2.2e-260 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ICLPFEEK_00153 7.76e-233 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
ICLPFEEK_00154 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ICLPFEEK_00155 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00156 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
ICLPFEEK_00157 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICLPFEEK_00159 5.41e-253 yhfE - - G - - - peptidase M42
ICLPFEEK_00160 3.36e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICLPFEEK_00161 1.7e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
ICLPFEEK_00162 3.9e-243 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
ICLPFEEK_00163 1.14e-145 yhfK - - GM - - - NmrA-like family
ICLPFEEK_00164 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
ICLPFEEK_00165 2.38e-86 yhfM - - - - - - -
ICLPFEEK_00166 1.11e-301 yhfN - - O - - - Peptidase M48
ICLPFEEK_00167 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
ICLPFEEK_00168 2.83e-205 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
ICLPFEEK_00169 4.42e-136 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
ICLPFEEK_00170 8.08e-259 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
ICLPFEEK_00171 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
ICLPFEEK_00172 1.86e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
ICLPFEEK_00173 1.18e-278 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
ICLPFEEK_00174 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
ICLPFEEK_00175 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_00176 5.7e-44 yhzC - - S - - - IDEAL
ICLPFEEK_00177 7.64e-142 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
ICLPFEEK_00178 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
ICLPFEEK_00179 8.17e-90 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
ICLPFEEK_00180 3.6e-122 - - - S - - - MepB protein
ICLPFEEK_00181 8e-166 yrpD - - S - - - Domain of unknown function, YrpD
ICLPFEEK_00182 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
ICLPFEEK_00183 2.2e-68 - - - S - - - Belongs to the UPF0145 family
ICLPFEEK_00184 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICLPFEEK_00185 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
ICLPFEEK_00186 4.12e-79 yhjD - - - - - - -
ICLPFEEK_00187 2.83e-145 yhjE - - S - - - SNARE associated Golgi protein
ICLPFEEK_00188 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
ICLPFEEK_00189 0.0 yhjG - - CH - - - FAD binding domain
ICLPFEEK_00190 1.03e-123 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
ICLPFEEK_00191 4.19e-263 yhjN - - S ko:K07120 - ko00000 membrane
ICLPFEEK_00192 2.27e-269 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_00193 2.72e-142 - - - K - - - QacR-like protein, C-terminal region
ICLPFEEK_00194 4.38e-123 yhjR - - S - - - Rubrerythrin
ICLPFEEK_00195 1.81e-162 ydfS - - S - - - Protein of unknown function (DUF421)
ICLPFEEK_00196 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
ICLPFEEK_00197 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
ICLPFEEK_00198 5.72e-284 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ICLPFEEK_00199 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
ICLPFEEK_00200 2.64e-67 yisB - - V - - - COG1403 Restriction endonuclease
ICLPFEEK_00201 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
ICLPFEEK_00202 1.67e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
ICLPFEEK_00203 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
ICLPFEEK_00204 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
ICLPFEEK_00205 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
ICLPFEEK_00206 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
ICLPFEEK_00207 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
ICLPFEEK_00208 1.13e-220 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
ICLPFEEK_00209 2.22e-78 yisL - - S - - - UPF0344 protein
ICLPFEEK_00210 2.35e-127 yisN - - S - - - Protein of unknown function (DUF2777)
ICLPFEEK_00211 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
ICLPFEEK_00212 1.19e-174 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
ICLPFEEK_00213 2.25e-312 yisQ - - V - - - Mate efflux family protein
ICLPFEEK_00214 4.22e-209 yisR - - K - - - Transcriptional regulator
ICLPFEEK_00215 5.37e-117 yisT - - S - - - DinB family
ICLPFEEK_00216 1.42e-113 yisX - - S - - - Pentapeptide repeats (9 copies)
ICLPFEEK_00217 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
ICLPFEEK_00218 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
ICLPFEEK_00219 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
ICLPFEEK_00220 1.59e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
ICLPFEEK_00221 9.67e-225 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
ICLPFEEK_00222 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
ICLPFEEK_00223 5.82e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
ICLPFEEK_00225 9.52e-204 yitS - - S - - - protein conserved in bacteria
ICLPFEEK_00226 1.61e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
ICLPFEEK_00227 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
ICLPFEEK_00228 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
ICLPFEEK_00229 1.49e-11 - - - - - - - -
ICLPFEEK_00230 1.52e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
ICLPFEEK_00231 9.1e-188 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
ICLPFEEK_00232 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
ICLPFEEK_00233 1.42e-106 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
ICLPFEEK_00234 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
ICLPFEEK_00235 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
ICLPFEEK_00236 9.02e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICLPFEEK_00237 5.39e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ICLPFEEK_00238 1.88e-177 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
ICLPFEEK_00239 1.19e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
ICLPFEEK_00240 1.69e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
ICLPFEEK_00241 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
ICLPFEEK_00242 3.02e-227 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICLPFEEK_00243 7.21e-39 yjzC - - S - - - YjzC-like protein
ICLPFEEK_00244 5.24e-33 yjzD - - S - - - Protein of unknown function (DUF2929)
ICLPFEEK_00245 1.4e-181 yjaU - - I - - - carboxylic ester hydrolase activity
ICLPFEEK_00246 2.12e-137 yjaV - - - - - - -
ICLPFEEK_00247 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
ICLPFEEK_00248 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
ICLPFEEK_00249 2.82e-44 yjzB - - - - - - -
ICLPFEEK_00250 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICLPFEEK_00251 2.71e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICLPFEEK_00252 1.84e-190 yjaZ - - O - - - Zn-dependent protease
ICLPFEEK_00253 7.17e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_00254 8.8e-239 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_00255 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
ICLPFEEK_00256 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICLPFEEK_00257 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICLPFEEK_00258 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
ICLPFEEK_00259 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
ICLPFEEK_00260 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
ICLPFEEK_00261 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICLPFEEK_00262 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICLPFEEK_00263 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_00264 2.19e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_00265 1.5e-299 - - - S - - - Putative glycosyl hydrolase domain
ICLPFEEK_00266 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICLPFEEK_00267 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ICLPFEEK_00268 1.18e-142 yjbE - - P - - - Integral membrane protein TerC family
ICLPFEEK_00269 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
ICLPFEEK_00270 4.36e-286 coiA - - S ko:K06198 - ko00000 Competence protein
ICLPFEEK_00271 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
ICLPFEEK_00272 3.14e-27 - - - - - - - -
ICLPFEEK_00273 1.49e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
ICLPFEEK_00274 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
ICLPFEEK_00275 1.32e-153 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ICLPFEEK_00276 4.41e-131 yjbK - - S - - - protein conserved in bacteria
ICLPFEEK_00277 3.5e-81 yjbL - - S - - - Belongs to the UPF0738 family
ICLPFEEK_00278 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
ICLPFEEK_00279 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICLPFEEK_00280 8.54e-214 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
ICLPFEEK_00281 5.48e-186 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
ICLPFEEK_00282 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICLPFEEK_00283 4.88e-178 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ICLPFEEK_00284 8.09e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
ICLPFEEK_00285 6.85e-279 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
ICLPFEEK_00286 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
ICLPFEEK_00287 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
ICLPFEEK_00288 8.18e-243 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
ICLPFEEK_00289 4.49e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
ICLPFEEK_00290 1.68e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
ICLPFEEK_00291 2.9e-126 yjbX - - S - - - Spore coat protein
ICLPFEEK_00292 1.79e-109 cotZ - - S ko:K06344 - ko00000 Spore coat protein
ICLPFEEK_00293 5.2e-122 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
ICLPFEEK_00294 2.33e-103 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
ICLPFEEK_00295 1.98e-36 cotW - - - ko:K06341 - ko00000 -
ICLPFEEK_00296 3.02e-74 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
ICLPFEEK_00297 1.24e-74 yjcA - - S - - - Protein of unknown function (DUF1360)
ICLPFEEK_00299 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
ICLPFEEK_00300 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
ICLPFEEK_00301 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
ICLPFEEK_00302 1.49e-49 - - - - - - - -
ICLPFEEK_00303 1.57e-185 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
ICLPFEEK_00304 1.13e-160 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
ICLPFEEK_00305 2.48e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
ICLPFEEK_00306 4.32e-48 - - - K - - - SpoVT / AbrB like domain
ICLPFEEK_00307 3.66e-98 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICLPFEEK_00308 2.43e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
ICLPFEEK_00309 8.63e-165 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
ICLPFEEK_00310 3.37e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
ICLPFEEK_00311 2.82e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
ICLPFEEK_00313 1.14e-41 - - - - - - - -
ICLPFEEK_00314 0.0 - - - S - - - Bacterial EndoU nuclease
ICLPFEEK_00316 1.76e-108 - - - - - - - -
ICLPFEEK_00318 2.43e-18 - - - - - - - -
ICLPFEEK_00319 6.79e-06 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
ICLPFEEK_00320 1.05e-75 - - - - - - - -
ICLPFEEK_00321 0.0 - - - S - - - Bacterial EndoU nuclease
ICLPFEEK_00322 1.18e-122 - - - - - - - -
ICLPFEEK_00325 1.7e-176 - - - - - - - -
ICLPFEEK_00328 1.13e-217 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
ICLPFEEK_00329 2.2e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
ICLPFEEK_00330 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
ICLPFEEK_00331 3.68e-107 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
ICLPFEEK_00332 8.39e-285 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
ICLPFEEK_00333 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
ICLPFEEK_00334 3.61e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
ICLPFEEK_00335 3.42e-280 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICLPFEEK_00336 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICLPFEEK_00337 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_00338 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
ICLPFEEK_00339 1.02e-179 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
ICLPFEEK_00340 1.29e-164 - - - S - - - Haloacid dehalogenase-like hydrolase
ICLPFEEK_00341 2.14e-192 - - - N - - - Kelch motif
ICLPFEEK_00343 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
ICLPFEEK_00345 1.91e-31 yjfB - - S - - - Putative motility protein
ICLPFEEK_00346 1.87e-93 yjgA - - T - - - Protein of unknown function (DUF2809)
ICLPFEEK_00347 6.05e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
ICLPFEEK_00348 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
ICLPFEEK_00349 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
ICLPFEEK_00350 7.66e-292 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
ICLPFEEK_00351 2.64e-287 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ICLPFEEK_00352 1.73e-40 - - - - - - - -
ICLPFEEK_00353 1.43e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
ICLPFEEK_00354 3.55e-159 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
ICLPFEEK_00355 4.76e-170 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_00356 7.42e-230 yjlA - - EG - - - Putative multidrug resistance efflux transporter
ICLPFEEK_00357 8.91e-121 yjlB - - S - - - Cupin domain
ICLPFEEK_00358 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
ICLPFEEK_00359 7.49e-281 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
ICLPFEEK_00360 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
ICLPFEEK_00361 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
ICLPFEEK_00362 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
ICLPFEEK_00363 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
ICLPFEEK_00364 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
ICLPFEEK_00365 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
ICLPFEEK_00366 4.32e-105 yjoA - - S - - - DinB family
ICLPFEEK_00367 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
ICLPFEEK_00369 8.26e-222 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
ICLPFEEK_00370 9.51e-81 yjqA - - S - - - Bacterial PH domain
ICLPFEEK_00371 7.87e-144 yjqB - - S - - - phage-related replication protein
ICLPFEEK_00372 6.51e-145 xkdA - - E - - - IrrE N-terminal-like domain
ICLPFEEK_00373 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
ICLPFEEK_00375 1.69e-22 xkdB - - K - - - sequence-specific DNA binding
ICLPFEEK_00376 9.14e-198 xkdC - - L - - - Bacterial dnaA protein
ICLPFEEK_00380 1.07e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
ICLPFEEK_00381 1.24e-47 xtmA - - - ko:K07474 - ko00000 -
ICLPFEEK_00382 9.95e-50 - - - - - - - -
ICLPFEEK_00384 5.6e-41 xkdX - - - - - - -
ICLPFEEK_00385 7.18e-184 xepA - - - - - - -
ICLPFEEK_00386 3.87e-51 xhlA - - S - - - Haemolysin XhlA
ICLPFEEK_00387 4.7e-52 xhlB - - S - - - SPP1 phage holin
ICLPFEEK_00388 5.16e-217 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
ICLPFEEK_00389 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
ICLPFEEK_00390 2.79e-174 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
ICLPFEEK_00391 8.61e-227 pit - - P ko:K03306 - ko00000 phosphate transporter
ICLPFEEK_00392 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
ICLPFEEK_00393 2.3e-312 steT - - E ko:K03294 - ko00000 amino acid
ICLPFEEK_00394 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
ICLPFEEK_00395 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICLPFEEK_00396 6.62e-231 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
ICLPFEEK_00398 2.36e-279 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICLPFEEK_00399 0.0 yubD - - P - - - Major Facilitator Superfamily
ICLPFEEK_00401 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
ICLPFEEK_00402 2.4e-205 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICLPFEEK_00403 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICLPFEEK_00404 6.75e-245 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_00405 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
ICLPFEEK_00406 5.87e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
ICLPFEEK_00407 4.18e-262 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
ICLPFEEK_00408 2.89e-222 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
ICLPFEEK_00409 1.39e-232 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_00410 1.46e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
ICLPFEEK_00411 4.37e-206 ykgA - - E - - - Amidinotransferase
ICLPFEEK_00412 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
ICLPFEEK_00413 1.34e-132 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ICLPFEEK_00414 7.06e-70 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
ICLPFEEK_00415 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
ICLPFEEK_00416 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
ICLPFEEK_00417 3.73e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICLPFEEK_00418 1.37e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICLPFEEK_00419 5.88e-94 ohrA - - O - - - Organic hydroperoxide resistance protein
ICLPFEEK_00420 7.54e-115 ohrR - - K - - - COG1846 Transcriptional regulators
ICLPFEEK_00421 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
ICLPFEEK_00422 1.83e-86 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICLPFEEK_00424 1.82e-277 - - - M - - - Glycosyl transferase family 2
ICLPFEEK_00425 1.72e-192 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
ICLPFEEK_00426 4.16e-279 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_00427 2.53e-161 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
ICLPFEEK_00428 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ICLPFEEK_00429 1.09e-227 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
ICLPFEEK_00430 5.66e-193 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ICLPFEEK_00431 6.53e-171 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
ICLPFEEK_00432 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_00433 1.19e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
ICLPFEEK_00434 1.13e-312 ydhD - - M - - - Glycosyl hydrolase
ICLPFEEK_00436 8.66e-310 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
ICLPFEEK_00437 1.23e-69 tnrA - - K - - - transcriptional
ICLPFEEK_00438 1.11e-23 - - - - - - - -
ICLPFEEK_00439 5.25e-37 ykoL - - - - - - -
ICLPFEEK_00440 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
ICLPFEEK_00441 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
ICLPFEEK_00442 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
ICLPFEEK_00443 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ICLPFEEK_00444 1.43e-131 ykoX - - S - - - membrane-associated protein
ICLPFEEK_00445 3.54e-174 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
ICLPFEEK_00446 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICLPFEEK_00447 2.53e-250 ykrI - - S - - - Anti-sigma factor N-terminus
ICLPFEEK_00448 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
ICLPFEEK_00449 6.86e-163 ykrK - - S - - - Domain of unknown function (DUF1836)
ICLPFEEK_00450 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
ICLPFEEK_00451 1.62e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
ICLPFEEK_00452 1.74e-149 - - - S - - - Protein of unknown function (DUF421)
ICLPFEEK_00453 3.07e-32 ykzE - - - - - - -
ICLPFEEK_00454 4.95e-246 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
ICLPFEEK_00455 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_00456 1.17e-116 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICLPFEEK_00458 9.34e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ICLPFEEK_00459 1.04e-288 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ICLPFEEK_00460 9.87e-194 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ICLPFEEK_00461 7.65e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
ICLPFEEK_00462 4.05e-291 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
ICLPFEEK_00463 1.4e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ICLPFEEK_00464 2.33e-149 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
ICLPFEEK_00465 6.37e-125 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ICLPFEEK_00467 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
ICLPFEEK_00468 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
ICLPFEEK_00469 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
ICLPFEEK_00470 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
ICLPFEEK_00471 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
ICLPFEEK_00472 6.6e-233 ykvI - - S - - - membrane
ICLPFEEK_00473 2.05e-257 - - - - - - - -
ICLPFEEK_00474 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ICLPFEEK_00475 8.23e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
ICLPFEEK_00476 1.76e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
ICLPFEEK_00477 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICLPFEEK_00479 6.24e-78 ykvN - - K - - - Transcriptional regulator
ICLPFEEK_00480 1.89e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
ICLPFEEK_00481 3.24e-44 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICLPFEEK_00482 4.38e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
ICLPFEEK_00483 5.43e-35 ykvS - - S - - - protein conserved in bacteria
ICLPFEEK_00484 7.17e-39 - - - - - - - -
ICLPFEEK_00485 1.77e-143 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
ICLPFEEK_00486 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICLPFEEK_00487 6.28e-116 stoA - - CO - - - thiol-disulfide
ICLPFEEK_00488 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
ICLPFEEK_00489 9.91e-265 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
ICLPFEEK_00491 2.12e-226 ykvZ - - K - - - Transcriptional regulator
ICLPFEEK_00492 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
ICLPFEEK_00493 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_00494 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
ICLPFEEK_00495 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICLPFEEK_00496 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00497 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
ICLPFEEK_00498 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
ICLPFEEK_00499 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
ICLPFEEK_00500 4.13e-86 - - - - - - - -
ICLPFEEK_00501 2.37e-177 ykwD - - J - - - protein with SCP PR1 domains
ICLPFEEK_00502 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
ICLPFEEK_00503 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_00504 2.81e-276 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
ICLPFEEK_00505 6.38e-15 - - - - - - - -
ICLPFEEK_00506 4.07e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
ICLPFEEK_00507 5.07e-108 ykyB - - S - - - YkyB-like protein
ICLPFEEK_00508 9.69e-310 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_00509 8.88e-117 ykuD - - S - - - protein conserved in bacteria
ICLPFEEK_00510 1.02e-203 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
ICLPFEEK_00511 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_00512 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
ICLPFEEK_00513 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
ICLPFEEK_00514 5.29e-121 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
ICLPFEEK_00515 4.54e-37 ykzF - - S - - - Antirepressor AbbA
ICLPFEEK_00516 8.55e-99 ykuL - - S - - - CBS domain
ICLPFEEK_00517 1.32e-215 ccpC - - K - - - Transcriptional regulator
ICLPFEEK_00518 3.15e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
ICLPFEEK_00519 2.47e-222 ykuO - - - - - - -
ICLPFEEK_00520 3.19e-105 fld - - C ko:K03839 - ko00000 Flavodoxin
ICLPFEEK_00521 2.49e-130 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ICLPFEEK_00522 2.39e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ICLPFEEK_00523 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
ICLPFEEK_00524 1.54e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
ICLPFEEK_00525 8.45e-106 ykuV - - CO - - - thiol-disulfide
ICLPFEEK_00526 7.46e-127 rok - - K - - - Repressor of ComK
ICLPFEEK_00527 2.53e-218 yknT - - - ko:K06437 - ko00000 -
ICLPFEEK_00528 1.72e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
ICLPFEEK_00529 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
ICLPFEEK_00530 1.29e-314 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
ICLPFEEK_00531 3.21e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
ICLPFEEK_00532 7.17e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
ICLPFEEK_00533 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ICLPFEEK_00534 7.2e-144 yknW - - S - - - Yip1 domain
ICLPFEEK_00535 2e-246 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICLPFEEK_00536 2.9e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_00537 1.09e-271 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
ICLPFEEK_00538 1.18e-172 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00539 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
ICLPFEEK_00540 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
ICLPFEEK_00541 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
ICLPFEEK_00542 4.47e-51 ykoA - - - - - - -
ICLPFEEK_00543 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ICLPFEEK_00544 1.6e-216 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICLPFEEK_00545 2.95e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
ICLPFEEK_00546 6.35e-18 - - - S - - - Uncharacterized protein YkpC
ICLPFEEK_00547 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
ICLPFEEK_00548 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
ICLPFEEK_00549 5.87e-313 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
ICLPFEEK_00550 1.58e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
ICLPFEEK_00551 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
ICLPFEEK_00552 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ICLPFEEK_00553 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICLPFEEK_00554 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
ICLPFEEK_00555 5.48e-190 ykrA - - S - - - hydrolases of the HAD superfamily
ICLPFEEK_00556 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICLPFEEK_00557 1.08e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
ICLPFEEK_00558 1.88e-136 ykyA - - L - - - Putative cell-wall binding lipoprotein
ICLPFEEK_00559 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
ICLPFEEK_00560 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_00561 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
ICLPFEEK_00562 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_00563 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_00564 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_00565 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_00566 0.0 - - - IQ - - - Phosphopantetheine attachment site
ICLPFEEK_00567 8.9e-272 - - - V - - - Beta-lactamase
ICLPFEEK_00568 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ICLPFEEK_00569 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ICLPFEEK_00570 7.27e-302 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICLPFEEK_00571 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ICLPFEEK_00572 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
ICLPFEEK_00573 4.87e-193 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
ICLPFEEK_00574 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
ICLPFEEK_00575 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
ICLPFEEK_00576 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
ICLPFEEK_00577 3.33e-33 ykzI - - - - - - -
ICLPFEEK_00578 9.88e-197 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
ICLPFEEK_00579 1.3e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
ICLPFEEK_00580 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
ICLPFEEK_00581 2.3e-255 ylaA - - - - - - -
ICLPFEEK_00582 5.66e-184 - - - - - - - -
ICLPFEEK_00583 5.38e-61 ylaB - - - - - - -
ICLPFEEK_00584 8.11e-121 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
ICLPFEEK_00586 3.48e-63 ylaE - - - - - - -
ICLPFEEK_00587 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
ICLPFEEK_00588 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
ICLPFEEK_00589 2.44e-65 - - - S - - - YlaH-like protein
ICLPFEEK_00590 6.78e-46 ylaI - - S - - - protein conserved in bacteria
ICLPFEEK_00591 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICLPFEEK_00592 8.09e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
ICLPFEEK_00593 3.02e-111 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ICLPFEEK_00594 6.57e-224 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
ICLPFEEK_00595 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
ICLPFEEK_00596 1.05e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
ICLPFEEK_00597 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ICLPFEEK_00598 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
ICLPFEEK_00599 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ICLPFEEK_00600 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
ICLPFEEK_00601 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICLPFEEK_00602 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
ICLPFEEK_00603 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
ICLPFEEK_00604 5.32e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
ICLPFEEK_00605 1.75e-80 ylbA - - S - - - YugN-like family
ICLPFEEK_00606 3.35e-96 ylbB - - T - - - COG0517 FOG CBS domain
ICLPFEEK_00607 2.8e-255 ylbC - - S - - - protein with SCP PR1 domains
ICLPFEEK_00608 1.52e-89 ylbD - - S - - - Putative coat protein
ICLPFEEK_00609 1.73e-48 ylbE - - S - - - YlbE-like protein
ICLPFEEK_00610 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
ICLPFEEK_00611 2.78e-57 ylbG - - S - - - UPF0298 protein
ICLPFEEK_00613 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
ICLPFEEK_00614 1.01e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICLPFEEK_00615 1.02e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
ICLPFEEK_00616 1.23e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
ICLPFEEK_00617 5.31e-241 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
ICLPFEEK_00618 1.34e-297 ylbM - - S - - - Belongs to the UPF0348 family
ICLPFEEK_00619 1.7e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
ICLPFEEK_00620 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
ICLPFEEK_00621 1.33e-112 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
ICLPFEEK_00622 1.38e-117 ylbP - - K - - - n-acetyltransferase
ICLPFEEK_00623 6.13e-213 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICLPFEEK_00624 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ICLPFEEK_00625 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
ICLPFEEK_00626 3.5e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ICLPFEEK_00627 2.4e-68 ftsL - - D - - - Essential cell division protein
ICLPFEEK_00628 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
ICLPFEEK_00629 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
ICLPFEEK_00630 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICLPFEEK_00631 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICLPFEEK_00632 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICLPFEEK_00633 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
ICLPFEEK_00634 5.69e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICLPFEEK_00635 1.17e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
ICLPFEEK_00636 9.33e-180 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ICLPFEEK_00637 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ICLPFEEK_00638 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICLPFEEK_00640 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
ICLPFEEK_00641 2.02e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
ICLPFEEK_00642 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICLPFEEK_00643 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICLPFEEK_00644 2.06e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
ICLPFEEK_00645 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
ICLPFEEK_00646 7.13e-52 ylmC - - S - - - sporulation protein
ICLPFEEK_00647 5.76e-207 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
ICLPFEEK_00648 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ICLPFEEK_00649 7.98e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ICLPFEEK_00650 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
ICLPFEEK_00651 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
ICLPFEEK_00652 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
ICLPFEEK_00653 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICLPFEEK_00654 6.48e-87 ylyA - - T - - - COG1734 DnaK suppressor protein
ICLPFEEK_00655 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICLPFEEK_00656 2.65e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
ICLPFEEK_00657 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICLPFEEK_00658 3.42e-297 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
ICLPFEEK_00659 6.51e-217 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
ICLPFEEK_00660 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ICLPFEEK_00661 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
ICLPFEEK_00662 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
ICLPFEEK_00663 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
ICLPFEEK_00664 7.67e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ICLPFEEK_00665 3.66e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ICLPFEEK_00666 2.2e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICLPFEEK_00668 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
ICLPFEEK_00669 8.54e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
ICLPFEEK_00670 4.53e-286 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
ICLPFEEK_00671 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
ICLPFEEK_00672 2.06e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
ICLPFEEK_00673 1.76e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
ICLPFEEK_00674 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
ICLPFEEK_00675 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
ICLPFEEK_00676 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
ICLPFEEK_00677 1.51e-198 yloC - - S - - - stress-induced protein
ICLPFEEK_00678 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
ICLPFEEK_00679 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
ICLPFEEK_00680 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ICLPFEEK_00681 9.26e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICLPFEEK_00682 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICLPFEEK_00683 5e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICLPFEEK_00684 4.76e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICLPFEEK_00685 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICLPFEEK_00686 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ICLPFEEK_00687 5.2e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
ICLPFEEK_00688 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
ICLPFEEK_00689 1.08e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ICLPFEEK_00690 6.15e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
ICLPFEEK_00691 6.68e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
ICLPFEEK_00692 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
ICLPFEEK_00693 3.65e-78 yloU - - S - - - protein conserved in bacteria
ICLPFEEK_00694 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
ICLPFEEK_00695 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
ICLPFEEK_00696 4.14e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
ICLPFEEK_00697 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICLPFEEK_00698 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
ICLPFEEK_00699 7.71e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ICLPFEEK_00700 3.22e-219 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
ICLPFEEK_00701 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
ICLPFEEK_00702 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICLPFEEK_00703 3.02e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ICLPFEEK_00704 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
ICLPFEEK_00705 2.28e-225 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ICLPFEEK_00706 1.34e-185 - - - S - - - Phosphotransferase enzyme family
ICLPFEEK_00707 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ICLPFEEK_00708 1.47e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICLPFEEK_00709 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
ICLPFEEK_00710 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
ICLPFEEK_00711 3.41e-80 ylqD - - S - - - YlqD protein
ICLPFEEK_00712 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICLPFEEK_00713 2.93e-178 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
ICLPFEEK_00714 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ICLPFEEK_00715 5.09e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ICLPFEEK_00716 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICLPFEEK_00717 0.0 ylqG - - - - - - -
ICLPFEEK_00718 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
ICLPFEEK_00719 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
ICLPFEEK_00720 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICLPFEEK_00721 4.8e-221 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
ICLPFEEK_00722 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICLPFEEK_00723 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ICLPFEEK_00724 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
ICLPFEEK_00725 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ICLPFEEK_00726 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ICLPFEEK_00727 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ICLPFEEK_00728 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
ICLPFEEK_00729 2.63e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
ICLPFEEK_00730 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
ICLPFEEK_00731 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
ICLPFEEK_00732 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
ICLPFEEK_00733 4.35e-126 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
ICLPFEEK_00734 5.19e-309 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
ICLPFEEK_00735 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
ICLPFEEK_00736 3.43e-89 ylxF - - S - - - MgtE intracellular N domain
ICLPFEEK_00737 1.72e-266 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
ICLPFEEK_00738 1.54e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
ICLPFEEK_00739 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
ICLPFEEK_00740 6.59e-81 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
ICLPFEEK_00741 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
ICLPFEEK_00742 1.08e-250 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICLPFEEK_00743 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
ICLPFEEK_00744 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
ICLPFEEK_00745 1.48e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
ICLPFEEK_00746 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
ICLPFEEK_00747 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
ICLPFEEK_00748 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICLPFEEK_00749 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICLPFEEK_00750 3.37e-251 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
ICLPFEEK_00751 5.68e-203 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
ICLPFEEK_00752 4.97e-249 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
ICLPFEEK_00753 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
ICLPFEEK_00754 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
ICLPFEEK_00755 1.45e-143 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
ICLPFEEK_00756 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
ICLPFEEK_00757 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICLPFEEK_00758 7.41e-97 ylxL - - - - - - -
ICLPFEEK_00759 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
ICLPFEEK_00760 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICLPFEEK_00761 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
ICLPFEEK_00762 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ICLPFEEK_00763 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICLPFEEK_00764 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
ICLPFEEK_00765 8.01e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
ICLPFEEK_00766 9.82e-298 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
ICLPFEEK_00767 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ICLPFEEK_00768 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICLPFEEK_00769 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
ICLPFEEK_00770 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
ICLPFEEK_00771 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
ICLPFEEK_00772 6.16e-63 ylxQ - - J - - - ribosomal protein
ICLPFEEK_00773 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICLPFEEK_00774 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
ICLPFEEK_00775 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICLPFEEK_00776 8.95e-222 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICLPFEEK_00777 4.5e-233 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
ICLPFEEK_00778 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICLPFEEK_00779 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
ICLPFEEK_00780 3.56e-233 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
ICLPFEEK_00781 2.51e-300 mlpA - - S - - - Belongs to the peptidase M16 family
ICLPFEEK_00782 2.17e-56 ymxH - - S - - - YlmC YmxH family
ICLPFEEK_00783 9.9e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
ICLPFEEK_00784 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
ICLPFEEK_00785 1.22e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICLPFEEK_00786 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
ICLPFEEK_00787 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICLPFEEK_00788 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICLPFEEK_00789 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
ICLPFEEK_00790 6.32e-42 - - - S - - - YlzJ-like protein
ICLPFEEK_00791 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
ICLPFEEK_00792 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00793 2.71e-297 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_00794 1.2e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
ICLPFEEK_00795 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
ICLPFEEK_00796 1.12e-306 albE - - S - - - Peptidase M16
ICLPFEEK_00797 4.28e-312 ymfH - - S - - - zinc protease
ICLPFEEK_00798 2.12e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
ICLPFEEK_00799 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
ICLPFEEK_00800 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
ICLPFEEK_00801 2.46e-180 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
ICLPFEEK_00802 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICLPFEEK_00803 8.03e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
ICLPFEEK_00804 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICLPFEEK_00805 1.34e-279 pbpX - - V - - - Beta-lactamase
ICLPFEEK_00806 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
ICLPFEEK_00807 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
ICLPFEEK_00808 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
ICLPFEEK_00809 7.41e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
ICLPFEEK_00810 7.42e-276 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
ICLPFEEK_00811 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ICLPFEEK_00812 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
ICLPFEEK_00813 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
ICLPFEEK_00814 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICLPFEEK_00815 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICLPFEEK_00817 1.72e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
ICLPFEEK_00818 1.21e-209 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
ICLPFEEK_00819 4.5e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
ICLPFEEK_00820 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
ICLPFEEK_00821 5.27e-49 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
ICLPFEEK_00822 6.55e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
ICLPFEEK_00823 4.51e-189 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
ICLPFEEK_00824 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
ICLPFEEK_00825 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
ICLPFEEK_00826 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_00827 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_00828 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
ICLPFEEK_00829 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
ICLPFEEK_00830 4.12e-295 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
ICLPFEEK_00831 1.81e-103 nucB - - M - - - Deoxyribonuclease NucA/NucB
ICLPFEEK_00832 2.21e-153 yoaK - - S - - - Membrane
ICLPFEEK_00833 2.78e-82 ymzB - - - - - - -
ICLPFEEK_00834 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
ICLPFEEK_00835 3.03e-06 - - - - - - - -
ICLPFEEK_00836 1.18e-164 ymaC - - S - - - Replication protein
ICLPFEEK_00837 7.27e-106 ymaD - - O - - - redox protein, regulator of disulfide bond formation
ICLPFEEK_00838 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
ICLPFEEK_00839 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
ICLPFEEK_00841 2.08e-77 ymaF - - S - - - YmaF family
ICLPFEEK_00842 7.63e-221 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICLPFEEK_00843 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
ICLPFEEK_00844 1.47e-59 - - - - - - - -
ICLPFEEK_00845 9.42e-29 ymzA - - - - - - -
ICLPFEEK_00846 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
ICLPFEEK_00847 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICLPFEEK_00848 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICLPFEEK_00849 2.72e-142 ymaB - - S - - - MutT family
ICLPFEEK_00850 3.22e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
ICLPFEEK_00851 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
ICLPFEEK_00852 1.15e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICLPFEEK_00853 1.01e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
ICLPFEEK_00854 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
ICLPFEEK_00855 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
ICLPFEEK_00856 1.27e-10 - - - L - - - Arm DNA-binding domain
ICLPFEEK_00857 4.59e-21 - - - - - - - -
ICLPFEEK_00858 2.12e-123 - - - - - - - -
ICLPFEEK_00860 2.11e-275 mrjp - - G - - - Major royal jelly protein
ICLPFEEK_00861 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
ICLPFEEK_00862 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
ICLPFEEK_00863 3.29e-280 xylR - - GK - - - ROK family
ICLPFEEK_00864 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
ICLPFEEK_00865 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
ICLPFEEK_00866 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
ICLPFEEK_00871 2.21e-27 - - - - - - - -
ICLPFEEK_00872 3.03e-74 dinB - - S - - - DinB family
ICLPFEEK_00873 1.07e-239 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
ICLPFEEK_00874 2.36e-06 ywlA - - S - - - Uncharacterised protein family (UPF0715)
ICLPFEEK_00875 5.71e-190 yoaP - - K - - - YoaP-like
ICLPFEEK_00876 7.16e-132 - - - J - - - Acetyltransferase (GNAT) domain
ICLPFEEK_00877 1.25e-97 - - - - - - - -
ICLPFEEK_00879 3.75e-158 - - - S - - - Domain of unknown function (DUF3885)
ICLPFEEK_00880 4.15e-258 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICLPFEEK_00881 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
ICLPFEEK_00882 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
ICLPFEEK_00883 7.75e-126 yvgO - - - - - - -
ICLPFEEK_00885 0.0 yobO - - M - - - Pectate lyase superfamily protein
ICLPFEEK_00886 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
ICLPFEEK_00887 9.79e-192 yndL - - S - - - Replication protein
ICLPFEEK_00888 1.74e-11 - - - - - - - -
ICLPFEEK_00889 6.29e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
ICLPFEEK_00890 2.25e-95 yndM - - S - - - Protein of unknown function (DUF2512)
ICLPFEEK_00892 1.35e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICLPFEEK_00893 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
ICLPFEEK_00894 5.22e-145 yneB - - L - - - resolvase
ICLPFEEK_00895 2.33e-43 ynzC - - S - - - UPF0291 protein
ICLPFEEK_00896 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICLPFEEK_00897 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
ICLPFEEK_00898 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
ICLPFEEK_00899 1.28e-32 ynzD - - S - - - Spo0E like sporulation regulatory protein
ICLPFEEK_00900 3.14e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
ICLPFEEK_00901 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
ICLPFEEK_00902 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
ICLPFEEK_00903 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
ICLPFEEK_00904 1.04e-83 cotM - - O ko:K06335 - ko00000 Spore coat protein
ICLPFEEK_00905 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
ICLPFEEK_00906 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
ICLPFEEK_00907 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ICLPFEEK_00908 3.46e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ICLPFEEK_00910 1.48e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
ICLPFEEK_00911 1.24e-98 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
ICLPFEEK_00912 4.68e-71 yneQ - - - - - - -
ICLPFEEK_00913 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
ICLPFEEK_00914 9.09e-121 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ICLPFEEK_00915 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
ICLPFEEK_00916 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICLPFEEK_00917 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICLPFEEK_00918 3.81e-20 - - - - - - - -
ICLPFEEK_00919 1.82e-63 ynfC - - - - - - -
ICLPFEEK_00920 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
ICLPFEEK_00921 2.82e-234 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
ICLPFEEK_00922 2.88e-249 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
ICLPFEEK_00923 1.84e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
ICLPFEEK_00924 1.23e-274 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
ICLPFEEK_00925 2.71e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_00926 1.57e-234 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
ICLPFEEK_00927 2.27e-288 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
ICLPFEEK_00928 1.59e-205 yndG - - S - - - DoxX-like family
ICLPFEEK_00929 2.4e-52 - - - S - - - Domain of unknown function (DUF4166)
ICLPFEEK_00930 0.0 yndJ - - S - - - YndJ-like protein
ICLPFEEK_00932 3.74e-282 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
ICLPFEEK_00933 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
ICLPFEEK_00934 1.8e-70 yvlA - - S - - - Domain of unknown function (DUF4870)
ICLPFEEK_00935 8.94e-317 - - - T - - - Histidine kinase
ICLPFEEK_00936 1.61e-165 - - - T - - - Transcriptional regulatory protein, C terminal
ICLPFEEK_00937 0.0 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
ICLPFEEK_00938 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
ICLPFEEK_00939 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_00940 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_00941 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_00942 4.25e-291 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
ICLPFEEK_00943 8.63e-180 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
ICLPFEEK_00944 2.23e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
ICLPFEEK_00945 8.91e-162 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ICLPFEEK_00946 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
ICLPFEEK_00947 3.48e-289 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
ICLPFEEK_00948 1.94e-247 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ICLPFEEK_00949 7.76e-169 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ICLPFEEK_00950 1.44e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
ICLPFEEK_00951 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
ICLPFEEK_00952 6.17e-191 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
ICLPFEEK_00953 5.53e-96 yngA - - S - - - membrane
ICLPFEEK_00954 1.93e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
ICLPFEEK_00955 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
ICLPFEEK_00956 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
ICLPFEEK_00957 7.4e-180 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
ICLPFEEK_00958 8.91e-217 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
ICLPFEEK_00959 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
ICLPFEEK_00960 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
ICLPFEEK_00961 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ICLPFEEK_00962 6.51e-269 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
ICLPFEEK_00963 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
ICLPFEEK_00964 1.67e-85 yngL - - S - - - Protein of unknown function (DUF1360)
ICLPFEEK_00965 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
ICLPFEEK_00966 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_00967 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
ICLPFEEK_00968 2.44e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
ICLPFEEK_00969 3.69e-312 yoeA - - V - - - MATE efflux family protein
ICLPFEEK_00970 4.66e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
ICLPFEEK_00972 3.97e-125 - - - L - - - Integrase
ICLPFEEK_00973 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
ICLPFEEK_00974 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
ICLPFEEK_00975 5.85e-257 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
ICLPFEEK_00976 3.29e-67 - - - K - - - Helix-turn-helix domain
ICLPFEEK_00977 1.36e-07 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICLPFEEK_00978 2.42e-204 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00979 5.3e-241 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
ICLPFEEK_00980 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
ICLPFEEK_00981 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
ICLPFEEK_00982 7.8e-207 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_00983 3.58e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICLPFEEK_00984 7.2e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICLPFEEK_00985 3.37e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
ICLPFEEK_00986 1.5e-101 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
ICLPFEEK_00987 1.66e-61 - - - L - - - Transposase
ICLPFEEK_00988 4.49e-184 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
ICLPFEEK_00989 6.26e-289 - - - K - - - helix_turn_helix, arabinose operon control protein
ICLPFEEK_00990 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_00991 1.45e-57 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICLPFEEK_00992 2.4e-182 yoxB - - - - - - -
ICLPFEEK_00993 1.81e-260 yoaB - - EGP - - - the major facilitator superfamily
ICLPFEEK_00994 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
ICLPFEEK_00995 3.78e-249 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICLPFEEK_00996 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICLPFEEK_00997 8.57e-22 yoaF - - - - - - -
ICLPFEEK_00999 2.41e-130 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
ICLPFEEK_01000 1.45e-60 - - - - - - - -
ICLPFEEK_01001 1.7e-115 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
ICLPFEEK_01002 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
ICLPFEEK_01003 3.67e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
ICLPFEEK_01004 3.17e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
ICLPFEEK_01005 4.57e-123 yobS - - K - - - Transcriptional regulator
ICLPFEEK_01006 2.41e-175 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
ICLPFEEK_01007 3.86e-119 yobW - - - - - - -
ICLPFEEK_01008 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
ICLPFEEK_01009 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ICLPFEEK_01010 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
ICLPFEEK_01011 6.89e-186 - - - J - - - Protein required for attachment to host cells
ICLPFEEK_01012 1.6e-123 yocC - - - - - - -
ICLPFEEK_01013 3.47e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
ICLPFEEK_01015 5.08e-170 yocH - - M - - - COG1388 FOG LysM repeat
ICLPFEEK_01016 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
ICLPFEEK_01017 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICLPFEEK_01019 5.24e-78 yocK - - T - - - general stress protein
ICLPFEEK_01020 2.71e-13 yocL - - - - - - -
ICLPFEEK_01021 3.51e-13 yocN - - - - - - -
ICLPFEEK_01022 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
ICLPFEEK_01023 9.63e-60 yozN - - - - - - -
ICLPFEEK_01024 6.36e-50 yocN - - - - - - -
ICLPFEEK_01025 5.32e-75 yozO - - S - - - Bacterial PH domain
ICLPFEEK_01027 4.69e-43 yozC - - - - - - -
ICLPFEEK_01028 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
ICLPFEEK_01029 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
ICLPFEEK_01030 3.49e-214 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
ICLPFEEK_01031 5.08e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
ICLPFEEK_01032 2.26e-218 yocS - - S ko:K03453 - ko00000 -transporter
ICLPFEEK_01033 1.99e-183 - - - S - - - Metallo-beta-lactamase superfamily
ICLPFEEK_01034 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
ICLPFEEK_01035 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
ICLPFEEK_01036 0.0 yojO - - P - - - Von Willebrand factor
ICLPFEEK_01037 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
ICLPFEEK_01038 9.26e-145 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ICLPFEEK_01039 1.34e-296 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
ICLPFEEK_01040 4.23e-288 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
ICLPFEEK_01041 1.64e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICLPFEEK_01043 2.76e-316 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
ICLPFEEK_01044 8.69e-195 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ICLPFEEK_01045 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
ICLPFEEK_01046 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
ICLPFEEK_01047 1.05e-30 - - - - - - - -
ICLPFEEK_01048 1.03e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
ICLPFEEK_01049 4.87e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
ICLPFEEK_01051 2.59e-89 iolK - - S - - - tautomerase
ICLPFEEK_01052 2.74e-92 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
ICLPFEEK_01053 1.2e-74 yodB - - K - - - transcriptional
ICLPFEEK_01054 3.3e-139 yodC - - C - - - nitroreductase
ICLPFEEK_01055 4.37e-143 yahD - - S ko:K06999 - ko00000 Carboxylesterase
ICLPFEEK_01056 2.39e-225 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
ICLPFEEK_01057 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
ICLPFEEK_01058 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICLPFEEK_01059 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
ICLPFEEK_01060 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
ICLPFEEK_01061 8.67e-170 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_01062 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
ICLPFEEK_01063 3.16e-168 yodH - - Q - - - Methyltransferase
ICLPFEEK_01064 1.68e-50 yodI - - - - - - -
ICLPFEEK_01065 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
ICLPFEEK_01066 1.82e-162 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
ICLPFEEK_01068 4.03e-73 yodL - - S - - - YodL-like
ICLPFEEK_01069 3.86e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
ICLPFEEK_01070 9.77e-34 yozD - - S - - - YozD-like protein
ICLPFEEK_01072 1.9e-161 yodN - - - - - - -
ICLPFEEK_01073 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
ICLPFEEK_01074 8.43e-64 yokU - - S - - - YokU-like protein, putative antitoxin
ICLPFEEK_01075 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
ICLPFEEK_01076 1.31e-208 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
ICLPFEEK_01077 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
ICLPFEEK_01078 2.3e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
ICLPFEEK_01079 1.19e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ICLPFEEK_01080 1.76e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICLPFEEK_01082 7.24e-188 yiiD - - K ko:K06323 - ko00000 acetyltransferase
ICLPFEEK_01083 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
ICLPFEEK_01084 6.96e-64 cgeC - - - ko:K06321 - ko00000 -
ICLPFEEK_01085 9.32e-92 cgeA - - - ko:K06319 - ko00000 -
ICLPFEEK_01086 5.69e-234 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
ICLPFEEK_01087 2e-285 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
ICLPFEEK_01088 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
ICLPFEEK_01092 1.49e-273 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
ICLPFEEK_01093 1.2e-115 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICLPFEEK_01094 0.0 baeB 3.1.2.6 - P ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Rhodanese Homology Domain
ICLPFEEK_01095 8.27e-293 - 1.8.5.4 - S ko:K17218 ko00920,map00920 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
ICLPFEEK_01096 2.85e-128 - - - T - - - helix_turn_helix, Lux Regulon
ICLPFEEK_01097 2.69e-254 - 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_01098 3.39e-110 - - - S ko:K07090 - ko00000 response to heat
ICLPFEEK_01100 9.7e-133 yokK - - S - - - SMI1 / KNR4 family
ICLPFEEK_01101 1.34e-167 - - - S - - - A nuclease of the HNH/ENDO VII superfamily with conserved WHH
ICLPFEEK_01102 0.0 yokA - - L - - - Recombinase
ICLPFEEK_01103 1.02e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
ICLPFEEK_01104 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
ICLPFEEK_01105 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICLPFEEK_01106 8.22e-90 ypoP - - K - - - transcriptional
ICLPFEEK_01107 4.79e-127 ypmS - - S - - - protein conserved in bacteria
ICLPFEEK_01108 2.58e-176 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
ICLPFEEK_01109 4.04e-149 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
ICLPFEEK_01110 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
ICLPFEEK_01111 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICLPFEEK_01112 1.97e-231 yplP - - K - - - Transcriptional regulator
ICLPFEEK_01113 3.69e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
ICLPFEEK_01114 1.71e-150 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ICLPFEEK_01115 5.2e-118 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICLPFEEK_01116 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICLPFEEK_01117 6.48e-148 ypjP - - S - - - YpjP-like protein
ICLPFEEK_01118 3.12e-175 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
ICLPFEEK_01119 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
ICLPFEEK_01120 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
ICLPFEEK_01121 2.1e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
ICLPFEEK_01122 5.04e-132 yagB - - S ko:K06950 - ko00000 phosphohydrolase
ICLPFEEK_01123 2.67e-116 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
ICLPFEEK_01124 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICLPFEEK_01125 1.56e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
ICLPFEEK_01126 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
ICLPFEEK_01127 1.27e-17 degR - - - - - - -
ICLPFEEK_01128 7.93e-50 - - - S - - - Protein of unknown function (DUF2564)
ICLPFEEK_01129 6.59e-40 ypeQ - - S - - - Zinc-finger
ICLPFEEK_01130 3.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
ICLPFEEK_01131 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ICLPFEEK_01132 7.37e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
ICLPFEEK_01134 8.18e-211 ypcP - - L - - - 5'3' exonuclease
ICLPFEEK_01135 2.44e-10 - - - - - - - -
ICLPFEEK_01136 7.03e-53 ypbS - - S - - - Protein of unknown function (DUF2533)
ICLPFEEK_01137 0.0 ypbR - - S - - - Dynamin family
ICLPFEEK_01138 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
ICLPFEEK_01139 6.51e-271 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
ICLPFEEK_01140 3.46e-143 - - - J - - - Acetyltransferase (GNAT) domain
ICLPFEEK_01141 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
ICLPFEEK_01142 2.17e-12 - - - S - - - Bacillus cereus group antimicrobial protein
ICLPFEEK_01143 2.34e-128 ydfR - - S - - - Protein of unknown function (DUF421)
ICLPFEEK_01144 1.32e-131 yrdC - - Q - - - Isochorismatase family
ICLPFEEK_01145 1.78e-06 - - - S - - - Bacillus cereus group antimicrobial protein
ICLPFEEK_01146 1.77e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
ICLPFEEK_01147 2e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ICLPFEEK_01148 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ICLPFEEK_01149 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
ICLPFEEK_01151 6.91e-31 - - - S - - - YpzG-like protein
ICLPFEEK_01152 7.1e-102 yqgA - - - - - - -
ICLPFEEK_01153 4.86e-281 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
ICLPFEEK_01154 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ICLPFEEK_01155 3.27e-129 ypsA - - S - - - Belongs to the UPF0398 family
ICLPFEEK_01156 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
ICLPFEEK_01158 1.99e-302 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
ICLPFEEK_01159 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
ICLPFEEK_01160 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
ICLPFEEK_01161 9.14e-96 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
ICLPFEEK_01162 3.1e-86 yppG - - S - - - YppG-like protein
ICLPFEEK_01166 0.000542 - - - - ko:K06430 - ko00000 -
ICLPFEEK_01167 2e-239 yppC - - S - - - Protein of unknown function (DUF2515)
ICLPFEEK_01168 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ICLPFEEK_01169 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
ICLPFEEK_01170 4.43e-120 ypoC - - - - - - -
ICLPFEEK_01171 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICLPFEEK_01172 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
ICLPFEEK_01173 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
ICLPFEEK_01174 1.78e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
ICLPFEEK_01175 2.03e-106 ypmB - - S - - - protein conserved in bacteria
ICLPFEEK_01176 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
ICLPFEEK_01177 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
ICLPFEEK_01178 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ICLPFEEK_01179 3.44e-203 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ICLPFEEK_01180 3.42e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
ICLPFEEK_01181 9.42e-232 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ICLPFEEK_01182 2.16e-282 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ICLPFEEK_01183 1.87e-271 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
ICLPFEEK_01184 1.56e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
ICLPFEEK_01185 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
ICLPFEEK_01186 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ICLPFEEK_01187 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
ICLPFEEK_01188 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
ICLPFEEK_01189 3.63e-292 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
ICLPFEEK_01190 2.05e-182 ypjB - - S - - - sporulation protein
ICLPFEEK_01191 9.19e-137 ypjA - - S - - - membrane
ICLPFEEK_01192 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
ICLPFEEK_01193 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
ICLPFEEK_01194 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
ICLPFEEK_01195 9.97e-103 ypiF - - S - - - Protein of unknown function (DUF2487)
ICLPFEEK_01196 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
ICLPFEEK_01197 6.42e-300 ypiA - - S - - - COG0457 FOG TPR repeat
ICLPFEEK_01198 7.29e-304 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
ICLPFEEK_01199 5.29e-262 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
ICLPFEEK_01200 9.08e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICLPFEEK_01201 1.97e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
ICLPFEEK_01202 3.12e-293 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ICLPFEEK_01203 3.43e-155 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
ICLPFEEK_01204 2.11e-170 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
ICLPFEEK_01205 6.09e-214 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICLPFEEK_01206 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICLPFEEK_01207 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
ICLPFEEK_01208 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ICLPFEEK_01209 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICLPFEEK_01210 3.47e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
ICLPFEEK_01211 1.47e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
ICLPFEEK_01212 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
ICLPFEEK_01213 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ICLPFEEK_01214 9.74e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
ICLPFEEK_01215 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
ICLPFEEK_01216 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
ICLPFEEK_01217 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICLPFEEK_01218 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ICLPFEEK_01219 5.88e-174 yphF - - - - - - -
ICLPFEEK_01220 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
ICLPFEEK_01221 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
ICLPFEEK_01222 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
ICLPFEEK_01223 6.19e-136 yphA - - - - - - -
ICLPFEEK_01224 1.87e-12 - - - S - - - YpzI-like protein
ICLPFEEK_01225 6.18e-240 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ICLPFEEK_01226 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
ICLPFEEK_01227 4.97e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
ICLPFEEK_01228 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
ICLPFEEK_01229 6.52e-05 ypfA - - M - - - type IV pilus assembly PilZ
ICLPFEEK_01230 8.8e-33 ypfA - - M - - - Flagellar protein YcgR
ICLPFEEK_01231 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
ICLPFEEK_01232 4.58e-214 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
ICLPFEEK_01233 1.11e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
ICLPFEEK_01234 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
ICLPFEEK_01235 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
ICLPFEEK_01236 4.07e-138 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
ICLPFEEK_01237 1.4e-190 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
ICLPFEEK_01238 6.69e-112 ypbF - - S - - - Protein of unknown function (DUF2663)
ICLPFEEK_01239 2.1e-139 ypbE - - M - - - Lysin motif
ICLPFEEK_01240 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
ICLPFEEK_01241 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
ICLPFEEK_01242 1.14e-257 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
ICLPFEEK_01243 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
ICLPFEEK_01244 1.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ICLPFEEK_01245 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICLPFEEK_01246 1.02e-256 rsiX - - - - - - -
ICLPFEEK_01247 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
ICLPFEEK_01248 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_01249 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_01250 6.24e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
ICLPFEEK_01251 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
ICLPFEEK_01252 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
ICLPFEEK_01253 7.38e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
ICLPFEEK_01254 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
ICLPFEEK_01255 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
ICLPFEEK_01256 1.14e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
ICLPFEEK_01257 1.51e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
ICLPFEEK_01258 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICLPFEEK_01259 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICLPFEEK_01261 1.99e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
ICLPFEEK_01262 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICLPFEEK_01263 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ICLPFEEK_01264 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ICLPFEEK_01265 9.75e-145 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
ICLPFEEK_01266 2.76e-270 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICLPFEEK_01267 4.92e-71 ypuD - - - - - - -
ICLPFEEK_01268 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
ICLPFEEK_01269 1.42e-107 ccdC1 - - O - - - Protein of unknown function (DUF1453)
ICLPFEEK_01270 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICLPFEEK_01271 5.04e-203 ypuA - - S - - - Secreted protein
ICLPFEEK_01272 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ICLPFEEK_01273 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
ICLPFEEK_01274 1.31e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
ICLPFEEK_01275 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
ICLPFEEK_01276 5.77e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
ICLPFEEK_01277 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
ICLPFEEK_01278 1.01e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
ICLPFEEK_01279 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
ICLPFEEK_01280 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICLPFEEK_01281 2.36e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
ICLPFEEK_01282 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
ICLPFEEK_01283 6.08e-274 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
ICLPFEEK_01284 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ICLPFEEK_01285 4.26e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICLPFEEK_01286 7.9e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
ICLPFEEK_01287 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
ICLPFEEK_01288 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
ICLPFEEK_01289 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
ICLPFEEK_01291 4.38e-47 yqkK - - - - - - -
ICLPFEEK_01292 1.96e-30 - - - - - - - -
ICLPFEEK_01293 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
ICLPFEEK_01294 3.55e-316 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
ICLPFEEK_01295 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
ICLPFEEK_01296 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
ICLPFEEK_01297 8.39e-78 ansR - - K - - - Transcriptional regulator
ICLPFEEK_01298 6.7e-286 yqxK - - L - - - DNA helicase
ICLPFEEK_01299 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
ICLPFEEK_01300 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
ICLPFEEK_01301 2.27e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
ICLPFEEK_01302 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
ICLPFEEK_01303 1.05e-228 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
ICLPFEEK_01304 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
ICLPFEEK_01305 9.32e-81 yqkB - - S - - - Belongs to the HesB IscA family
ICLPFEEK_01306 5.45e-231 yqkA - - K - - - GrpB protein
ICLPFEEK_01307 5.96e-81 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
ICLPFEEK_01308 2.81e-115 yqjY - - K ko:K06977 - ko00000 acetyltransferase
ICLPFEEK_01309 1.7e-301 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICLPFEEK_01310 3.89e-77 - - - S - - - YolD-like protein
ICLPFEEK_01312 1.11e-243 yueF - - S - - - transporter activity
ICLPFEEK_01314 2.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICLPFEEK_01315 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
ICLPFEEK_01316 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
ICLPFEEK_01317 1.29e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_01318 6.11e-229 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
ICLPFEEK_01319 2.88e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICLPFEEK_01320 2.05e-176 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
ICLPFEEK_01321 1.17e-307 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
ICLPFEEK_01322 5.93e-283 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
ICLPFEEK_01323 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
ICLPFEEK_01324 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_01325 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_01326 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_01348 7.73e-104 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
ICLPFEEK_01349 1.28e-170 yteA - - T - - - COG1734 DnaK suppressor protein
ICLPFEEK_01350 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
ICLPFEEK_01351 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ICLPFEEK_01352 7.53e-201 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
ICLPFEEK_01353 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ICLPFEEK_01354 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ICLPFEEK_01355 1.74e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
ICLPFEEK_01356 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
ICLPFEEK_01357 3.85e-237 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
ICLPFEEK_01358 2.22e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
ICLPFEEK_01359 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
ICLPFEEK_01360 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
ICLPFEEK_01361 8.41e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
ICLPFEEK_01362 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ICLPFEEK_01363 4.4e-101 ytkA - - S - - - YtkA-like
ICLPFEEK_01365 3.12e-100 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
ICLPFEEK_01366 2.12e-80 ytkC - - S - - - Bacteriophage holin family
ICLPFEEK_01367 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
ICLPFEEK_01368 2.19e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
ICLPFEEK_01369 2.6e-185 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
ICLPFEEK_01370 3.88e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
ICLPFEEK_01371 4.02e-192 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
ICLPFEEK_01372 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
ICLPFEEK_01373 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ICLPFEEK_01374 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICLPFEEK_01375 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
ICLPFEEK_01376 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
ICLPFEEK_01377 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICLPFEEK_01378 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
ICLPFEEK_01379 2.45e-272 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
ICLPFEEK_01380 1.1e-186 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
ICLPFEEK_01382 1.08e-137 ytqB - - J - - - Putative rRNA methylase
ICLPFEEK_01383 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
ICLPFEEK_01384 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_01385 7.18e-170 aveG - - Q - - - Thioesterase domain
ICLPFEEK_01386 3.89e-241 - - - C - - - Nitroreductase
ICLPFEEK_01387 0.0 - - - Q ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_01388 0.0 - - - Q ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_01389 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_01390 5.31e-265 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
ICLPFEEK_01391 0.0 - - - IQ - - - AMP-binding enzyme
ICLPFEEK_01392 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
ICLPFEEK_01394 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
ICLPFEEK_01395 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_01396 2.06e-232 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
ICLPFEEK_01397 3.18e-236 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
ICLPFEEK_01398 1.7e-214 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
ICLPFEEK_01399 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_01400 4.75e-288 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
ICLPFEEK_01401 1.57e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_01402 2.23e-224 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
ICLPFEEK_01403 2.3e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_01404 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
ICLPFEEK_01405 2.13e-169 ywaF - - S - - - Integral membrane protein
ICLPFEEK_01406 2.46e-271 yttB - - EGP - - - Major facilitator superfamily
ICLPFEEK_01407 8.76e-177 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
ICLPFEEK_01408 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
ICLPFEEK_01409 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
ICLPFEEK_01410 6.05e-69 ytwF - - P - - - Sulfurtransferase
ICLPFEEK_01411 2.06e-112 - - - M - - - Acetyltransferase (GNAT) domain
ICLPFEEK_01412 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
ICLPFEEK_01413 1.01e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
ICLPFEEK_01414 6.79e-219 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
ICLPFEEK_01415 1.44e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
ICLPFEEK_01416 1.35e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_01417 2.14e-36 yteV - - S - - - Sporulation protein Cse60
ICLPFEEK_01418 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
ICLPFEEK_01419 9.17e-300 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
ICLPFEEK_01420 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICLPFEEK_01421 8.68e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
ICLPFEEK_01422 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
ICLPFEEK_01423 2.31e-166 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
ICLPFEEK_01424 9.45e-281 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
ICLPFEEK_01425 1.48e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
ICLPFEEK_01426 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
ICLPFEEK_01427 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
ICLPFEEK_01428 3.82e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ICLPFEEK_01429 5.36e-219 ytlQ - - - - - - -
ICLPFEEK_01430 6.37e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
ICLPFEEK_01431 2.93e-199 ytmP - - M - - - Phosphotransferase
ICLPFEEK_01432 6.69e-61 ytzH - - S - - - YtzH-like protein
ICLPFEEK_01433 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ICLPFEEK_01434 6.76e-212 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
ICLPFEEK_01435 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
ICLPFEEK_01436 9.96e-69 ytzB - - S - - - small secreted protein
ICLPFEEK_01437 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
ICLPFEEK_01438 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
ICLPFEEK_01439 5.47e-76 ytpP - - CO - - - Thioredoxin
ICLPFEEK_01440 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
ICLPFEEK_01441 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICLPFEEK_01442 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
ICLPFEEK_01443 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
ICLPFEEK_01444 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICLPFEEK_01445 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
ICLPFEEK_01446 5.9e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
ICLPFEEK_01447 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
ICLPFEEK_01448 2.06e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
ICLPFEEK_01449 1.82e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
ICLPFEEK_01450 3.66e-156 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
ICLPFEEK_01451 3.49e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
ICLPFEEK_01452 5.07e-151 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
ICLPFEEK_01453 2.96e-157 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
ICLPFEEK_01454 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
ICLPFEEK_01455 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICLPFEEK_01456 3.06e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
ICLPFEEK_01457 9.98e-161 ygaZ - - E - - - AzlC protein
ICLPFEEK_01458 7.76e-191 - - - K - - - Transcriptional regulator
ICLPFEEK_01459 6.08e-194 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICLPFEEK_01460 1.29e-180 - - - E - - - GDSL-like Lipase/Acylhydrolase family
ICLPFEEK_01462 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
ICLPFEEK_01464 9.55e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICLPFEEK_01465 1.4e-44 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
ICLPFEEK_01466 2.93e-41 - - - - - - - -
ICLPFEEK_01467 1.99e-39 - - - S - - - Phage-like element PBSX protein XtrA
ICLPFEEK_01469 7.51e-116 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
ICLPFEEK_01471 6.45e-132 - - - - - - - -
ICLPFEEK_01473 1.96e-136 yokH - - G - - - SMI1 / KNR4 family
ICLPFEEK_01474 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
ICLPFEEK_01475 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICLPFEEK_01476 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
ICLPFEEK_01477 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
ICLPFEEK_01478 3.57e-143 yttP - - K - - - Transcriptional regulator
ICLPFEEK_01479 1.85e-199 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
ICLPFEEK_01480 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ICLPFEEK_01481 1.68e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
ICLPFEEK_01482 1.42e-268 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
ICLPFEEK_01483 1.47e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICLPFEEK_01484 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
ICLPFEEK_01485 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
ICLPFEEK_01486 0.0 ytcJ - - S - - - amidohydrolase
ICLPFEEK_01487 8.09e-197 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICLPFEEK_01488 2.23e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
ICLPFEEK_01489 2.77e-114 yteJ - - S - - - RDD family
ICLPFEEK_01490 3.82e-158 ytfI - - S - - - Protein of unknown function (DUF2953)
ICLPFEEK_01491 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
ICLPFEEK_01492 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ICLPFEEK_01493 7.8e-237 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
ICLPFEEK_01494 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICLPFEEK_01495 4.03e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
ICLPFEEK_01496 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
ICLPFEEK_01497 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
ICLPFEEK_01499 2.06e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_01500 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
ICLPFEEK_01501 6.77e-305 ytoI - - K - - - transcriptional regulator containing CBS domains
ICLPFEEK_01502 1.06e-63 ytpI - - S - - - YtpI-like protein
ICLPFEEK_01503 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
ICLPFEEK_01504 7.04e-32 - - - - - - - -
ICLPFEEK_01505 2.64e-114 ytrI - - - - - - -
ICLPFEEK_01506 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
ICLPFEEK_01507 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
ICLPFEEK_01508 1.48e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
ICLPFEEK_01509 1.53e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICLPFEEK_01510 1.15e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
ICLPFEEK_01511 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ICLPFEEK_01512 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
ICLPFEEK_01513 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
ICLPFEEK_01514 9.96e-248 ytvI - - S - - - sporulation integral membrane protein YtvI
ICLPFEEK_01515 5.65e-96 ytwI - - S - - - membrane
ICLPFEEK_01516 2.33e-84 yjdF3 - - S - - - Protein of unknown function (DUF2992)
ICLPFEEK_01517 1.42e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
ICLPFEEK_01518 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
ICLPFEEK_01519 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
ICLPFEEK_01520 2.9e-167 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_01521 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
ICLPFEEK_01522 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICLPFEEK_01523 9.87e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ICLPFEEK_01524 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
ICLPFEEK_01525 1.52e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICLPFEEK_01526 1.93e-206 ytbE - - S - - - reductase
ICLPFEEK_01527 4.15e-261 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
ICLPFEEK_01528 1.69e-89 ytcD - - K - - - Transcriptional regulator
ICLPFEEK_01529 1.09e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICLPFEEK_01530 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ICLPFEEK_01531 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICLPFEEK_01532 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
ICLPFEEK_01533 1.42e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
ICLPFEEK_01534 4.64e-142 ytxB - - S - - - SNARE associated Golgi protein
ICLPFEEK_01535 5.94e-199 ytxC - - S - - - YtxC-like family
ICLPFEEK_01536 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICLPFEEK_01537 2.52e-194 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
ICLPFEEK_01538 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_01539 1.05e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
ICLPFEEK_01540 2.76e-69 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
ICLPFEEK_01541 1.08e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
ICLPFEEK_01542 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICLPFEEK_01543 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
ICLPFEEK_01544 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICLPFEEK_01545 8.03e-58 ysdA - - S - - - Membrane
ICLPFEEK_01546 9.71e-90 ysdB - - S - - - Sigma-w pathway protein YsdB
ICLPFEEK_01547 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
ICLPFEEK_01548 1.71e-241 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
ICLPFEEK_01549 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
ICLPFEEK_01550 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
ICLPFEEK_01551 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
ICLPFEEK_01552 1.85e-182 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
ICLPFEEK_01553 2.09e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
ICLPFEEK_01554 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
ICLPFEEK_01555 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
ICLPFEEK_01556 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
ICLPFEEK_01557 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
ICLPFEEK_01558 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
ICLPFEEK_01559 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
ICLPFEEK_01560 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
ICLPFEEK_01561 4.53e-264 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
ICLPFEEK_01562 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
ICLPFEEK_01563 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICLPFEEK_01564 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICLPFEEK_01565 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICLPFEEK_01566 7.57e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICLPFEEK_01567 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ICLPFEEK_01568 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
ICLPFEEK_01569 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
ICLPFEEK_01570 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ICLPFEEK_01571 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
ICLPFEEK_01572 1.77e-165 ywbB - - S - - - Protein of unknown function (DUF2711)
ICLPFEEK_01573 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ICLPFEEK_01574 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_01575 7.4e-180 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
ICLPFEEK_01576 8.64e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
ICLPFEEK_01577 5.22e-229 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
ICLPFEEK_01578 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
ICLPFEEK_01579 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
ICLPFEEK_01580 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ICLPFEEK_01581 1.49e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
ICLPFEEK_01582 6.01e-104 yslB - - S - - - Protein of unknown function (DUF2507)
ICLPFEEK_01583 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
ICLPFEEK_01584 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
ICLPFEEK_01585 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
ICLPFEEK_01586 2.67e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
ICLPFEEK_01587 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_01588 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
ICLPFEEK_01589 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
ICLPFEEK_01590 7.73e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
ICLPFEEK_01591 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ICLPFEEK_01592 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICLPFEEK_01593 1.21e-120 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
ICLPFEEK_01598 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
ICLPFEEK_01599 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
ICLPFEEK_01600 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ICLPFEEK_01601 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICLPFEEK_01602 3.68e-256 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
ICLPFEEK_01603 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICLPFEEK_01604 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICLPFEEK_01605 2.34e-241 ysoA - - H - - - Tetratricopeptide repeat
ICLPFEEK_01606 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ICLPFEEK_01607 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICLPFEEK_01608 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
ICLPFEEK_01609 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ICLPFEEK_01610 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
ICLPFEEK_01611 8.26e-116 ysxD - - - - - - -
ICLPFEEK_01612 9.08e-317 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ICLPFEEK_01613 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
ICLPFEEK_01614 4.44e-224 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
ICLPFEEK_01615 9.78e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
ICLPFEEK_01616 1.2e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
ICLPFEEK_01617 1.62e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
ICLPFEEK_01618 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
ICLPFEEK_01619 1.89e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ICLPFEEK_01620 1.53e-35 - - - - - - - -
ICLPFEEK_01621 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ICLPFEEK_01622 2.04e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
ICLPFEEK_01623 1.27e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
ICLPFEEK_01624 2.67e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
ICLPFEEK_01625 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
ICLPFEEK_01626 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
ICLPFEEK_01627 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
ICLPFEEK_01628 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
ICLPFEEK_01629 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
ICLPFEEK_01630 1.68e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
ICLPFEEK_01631 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
ICLPFEEK_01632 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
ICLPFEEK_01633 3.59e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
ICLPFEEK_01634 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
ICLPFEEK_01635 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
ICLPFEEK_01636 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
ICLPFEEK_01637 3.64e-140 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
ICLPFEEK_01638 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICLPFEEK_01639 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
ICLPFEEK_01640 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
ICLPFEEK_01641 3.02e-124 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
ICLPFEEK_01642 5.11e-288 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
ICLPFEEK_01643 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
ICLPFEEK_01644 9.86e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
ICLPFEEK_01645 1.04e-272 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ICLPFEEK_01646 2.6e-263 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
ICLPFEEK_01647 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICLPFEEK_01649 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
ICLPFEEK_01650 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ICLPFEEK_01651 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ICLPFEEK_01652 1.39e-28 yrzS - - S - - - Protein of unknown function (DUF2905)
ICLPFEEK_01653 4.96e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICLPFEEK_01654 2.01e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ICLPFEEK_01655 1.78e-51 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
ICLPFEEK_01656 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
ICLPFEEK_01657 2.03e-143 yrbG - - S - - - membrane
ICLPFEEK_01658 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICLPFEEK_01659 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
ICLPFEEK_01660 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICLPFEEK_01661 2.65e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
ICLPFEEK_01662 4.68e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
ICLPFEEK_01663 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
ICLPFEEK_01664 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICLPFEEK_01665 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICLPFEEK_01666 3.48e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ICLPFEEK_01667 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
ICLPFEEK_01670 7.37e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
ICLPFEEK_01671 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ICLPFEEK_01672 1.18e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
ICLPFEEK_01673 1.85e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
ICLPFEEK_01674 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_01675 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
ICLPFEEK_01676 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ICLPFEEK_01677 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
ICLPFEEK_01678 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ICLPFEEK_01679 1.76e-107 yrrD - - S - - - protein conserved in bacteria
ICLPFEEK_01680 8.4e-42 yrzR - - - - - - -
ICLPFEEK_01681 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
ICLPFEEK_01682 7.94e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
ICLPFEEK_01683 2.38e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
ICLPFEEK_01684 1.56e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
ICLPFEEK_01685 2.8e-171 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
ICLPFEEK_01686 2.82e-238 yrrI - - S - - - AI-2E family transporter
ICLPFEEK_01687 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICLPFEEK_01688 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
ICLPFEEK_01689 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICLPFEEK_01690 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
ICLPFEEK_01691 2.82e-259 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICLPFEEK_01692 4.01e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
ICLPFEEK_01693 1.33e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
ICLPFEEK_01694 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
ICLPFEEK_01695 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
ICLPFEEK_01696 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICLPFEEK_01697 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
ICLPFEEK_01698 1.85e-126 yrrS - - S - - - Protein of unknown function (DUF1510)
ICLPFEEK_01699 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
ICLPFEEK_01700 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
ICLPFEEK_01701 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICLPFEEK_01702 7.96e-219 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
ICLPFEEK_01703 1.17e-271 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
ICLPFEEK_01704 3.31e-47 yrhC - - S - - - YrhC-like protein
ICLPFEEK_01705 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
ICLPFEEK_01706 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
ICLPFEEK_01707 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
ICLPFEEK_01708 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
ICLPFEEK_01709 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
ICLPFEEK_01710 1.33e-122 yrhH - - Q - - - methyltransferase
ICLPFEEK_01711 3.36e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
ICLPFEEK_01712 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
ICLPFEEK_01713 2.38e-273 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_01714 1.94e-213 yybE - - K - - - Transcriptional regulator
ICLPFEEK_01715 1.96e-108 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICLPFEEK_01716 2.06e-234 romA - - S - - - Beta-lactamase superfamily domain
ICLPFEEK_01717 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
ICLPFEEK_01718 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_01719 4.54e-243 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
ICLPFEEK_01720 1.23e-169 - - - K - - - Helix-turn-helix domain, rpiR family
ICLPFEEK_01721 3.29e-193 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
ICLPFEEK_01722 3.71e-193 supH - - S - - - hydrolase
ICLPFEEK_01724 1.42e-122 - - - S - - - DinB family
ICLPFEEK_01725 3.54e-113 - - - K - - - acetyltransferase
ICLPFEEK_01726 1.63e-131 yqaC - - F - - - adenylate kinase activity
ICLPFEEK_01727 3.27e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
ICLPFEEK_01728 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
ICLPFEEK_01730 2.5e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
ICLPFEEK_01731 2.67e-308 yrkQ - - T - - - Histidine kinase
ICLPFEEK_01732 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
ICLPFEEK_01733 6.92e-123 - - - K - - - Transcriptional regulator PadR-like family
ICLPFEEK_01734 1.72e-209 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
ICLPFEEK_01735 5.58e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICLPFEEK_01736 4.18e-282 - - - EGP - - - Transmembrane secretion effector
ICLPFEEK_01737 1.68e-18 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
ICLPFEEK_01738 2.92e-138 yqeD - - S - - - SNARE associated Golgi protein
ICLPFEEK_01739 1.2e-182 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
ICLPFEEK_01740 1.85e-180 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
ICLPFEEK_01742 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
ICLPFEEK_01743 1.17e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
ICLPFEEK_01744 2.52e-202 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICLPFEEK_01745 3.12e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
ICLPFEEK_01746 7.09e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICLPFEEK_01747 1.68e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
ICLPFEEK_01748 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ICLPFEEK_01749 1.02e-179 yqeM - - Q - - - Methyltransferase
ICLPFEEK_01750 1.19e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICLPFEEK_01751 1.51e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
ICLPFEEK_01752 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
ICLPFEEK_01753 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
ICLPFEEK_01754 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
ICLPFEEK_01755 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
ICLPFEEK_01756 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ICLPFEEK_01757 9.09e-280 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
ICLPFEEK_01758 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
ICLPFEEK_01759 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ICLPFEEK_01760 2.04e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
ICLPFEEK_01761 5.74e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ICLPFEEK_01762 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICLPFEEK_01763 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
ICLPFEEK_01764 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ICLPFEEK_01765 6.58e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
ICLPFEEK_01766 1.75e-181 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ICLPFEEK_01767 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
ICLPFEEK_01768 8.3e-203 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
ICLPFEEK_01769 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
ICLPFEEK_01770 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
ICLPFEEK_01771 3.28e-296 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
ICLPFEEK_01772 4.48e-189 yqfA - - S - - - UPF0365 protein
ICLPFEEK_01773 7.93e-89 yqfB - - - - - - -
ICLPFEEK_01774 3.57e-61 yqfC - - S - - - sporulation protein YqfC
ICLPFEEK_01775 8.17e-286 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
ICLPFEEK_01776 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
ICLPFEEK_01777 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
ICLPFEEK_01778 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICLPFEEK_01779 6.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
ICLPFEEK_01780 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
ICLPFEEK_01781 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICLPFEEK_01782 6e-24 - - - S - - - YqzL-like protein
ICLPFEEK_01783 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
ICLPFEEK_01784 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
ICLPFEEK_01785 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
ICLPFEEK_01786 5.89e-145 ccpN - - K - - - CBS domain
ICLPFEEK_01787 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ICLPFEEK_01788 3.33e-113 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
ICLPFEEK_01789 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ICLPFEEK_01790 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ICLPFEEK_01791 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
ICLPFEEK_01792 2.97e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
ICLPFEEK_01793 7.93e-271 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICLPFEEK_01794 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ICLPFEEK_01795 4.16e-89 yqfQ - - S - - - YqfQ-like protein
ICLPFEEK_01796 1.2e-314 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ICLPFEEK_01797 4.23e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ICLPFEEK_01798 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
ICLPFEEK_01799 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
ICLPFEEK_01800 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
ICLPFEEK_01801 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
ICLPFEEK_01802 3.34e-80 yqfX - - S - - - membrane
ICLPFEEK_01803 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ICLPFEEK_01804 1.84e-64 yqfZ - - M ko:K06417 - ko00000 LysM domain
ICLPFEEK_01805 7.3e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
ICLPFEEK_01806 4.77e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
ICLPFEEK_01807 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
ICLPFEEK_01808 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
ICLPFEEK_01809 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
ICLPFEEK_01810 3.3e-172 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
ICLPFEEK_01811 1.55e-72 - - - L - - - COG2963 Transposase and inactivated derivatives
ICLPFEEK_01812 4.49e-232 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
ICLPFEEK_01814 1.34e-20 - - - - - - - -
ICLPFEEK_01815 5.09e-35 yxeD - - - - - - -
ICLPFEEK_01816 2.06e-42 yxeE - - - - - - -
ICLPFEEK_01819 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
ICLPFEEK_01820 6.05e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
ICLPFEEK_01821 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICLPFEEK_01822 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICLPFEEK_01823 4.69e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
ICLPFEEK_01824 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
ICLPFEEK_01825 2.13e-228 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
ICLPFEEK_01826 1.41e-302 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
ICLPFEEK_01827 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ICLPFEEK_01828 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
ICLPFEEK_01829 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
ICLPFEEK_01830 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
ICLPFEEK_01831 1.44e-86 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
ICLPFEEK_01832 0.0 - - - L - - - HKD family nuclease
ICLPFEEK_01833 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_01834 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
ICLPFEEK_01835 1.26e-96 yxiE - - T - - - Belongs to the universal stress protein A family
ICLPFEEK_01836 1.78e-209 yxxF - - EG - - - EamA-like transporter family
ICLPFEEK_01837 1.2e-260 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
ICLPFEEK_01839 2.34e-93 yxxG - - - - - - -
ICLPFEEK_01840 5.75e-98 yxiG - - - - - - -
ICLPFEEK_01842 4.01e-118 yxiI - - S - - - Protein of unknown function (DUF2716)
ICLPFEEK_01843 4.25e-82 - - - S - - - SMI1-KNR4 cell-wall
ICLPFEEK_01846 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
ICLPFEEK_01847 2.21e-283 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
ICLPFEEK_01848 1.19e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
ICLPFEEK_01849 8.45e-187 bglS - - M - - - licheninase activity
ICLPFEEK_01850 2.84e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
ICLPFEEK_01851 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
ICLPFEEK_01852 1.61e-68 yxiS - - - - - - -
ICLPFEEK_01853 3.75e-126 - - - T - - - Domain of unknown function (DUF4163)
ICLPFEEK_01854 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICLPFEEK_01855 2.65e-215 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
ICLPFEEK_01856 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
ICLPFEEK_01857 7.42e-112 yxjI - - S - - - LURP-one-related
ICLPFEEK_01860 8.44e-303 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
ICLPFEEK_01861 3.94e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
ICLPFEEK_01862 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
ICLPFEEK_01863 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICLPFEEK_01864 2.66e-217 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
ICLPFEEK_01865 6.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_01866 1.2e-200 yxkH - - G - - - Polysaccharide deacetylase
ICLPFEEK_01867 4.75e-289 cimH - - C - - - COG3493 Na citrate symporter
ICLPFEEK_01868 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
ICLPFEEK_01869 9.56e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
ICLPFEEK_01870 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
ICLPFEEK_01871 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
ICLPFEEK_01872 1.85e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICLPFEEK_01873 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
ICLPFEEK_01874 2.75e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
ICLPFEEK_01875 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
ICLPFEEK_01876 6.75e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
ICLPFEEK_01877 2.17e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
ICLPFEEK_01878 3.93e-217 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
ICLPFEEK_01879 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
ICLPFEEK_01880 7.31e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICLPFEEK_01881 6.75e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_01882 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_01883 2.8e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ICLPFEEK_01884 3.3e-79 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
ICLPFEEK_01885 9.23e-214 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
ICLPFEEK_01886 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_01887 2e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_01888 4.77e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
ICLPFEEK_01889 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
ICLPFEEK_01890 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
ICLPFEEK_01891 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICLPFEEK_01892 2.9e-68 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_01893 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
ICLPFEEK_01894 1.41e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
ICLPFEEK_01895 1.31e-290 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ICLPFEEK_01896 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_01897 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
ICLPFEEK_01898 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_01899 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
ICLPFEEK_01900 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
ICLPFEEK_01901 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
ICLPFEEK_01902 4.43e-209 gspA - - M - - - General stress
ICLPFEEK_01903 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
ICLPFEEK_01904 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICLPFEEK_01905 1.29e-88 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
ICLPFEEK_01906 1.53e-286 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
ICLPFEEK_01907 3.65e-221 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
ICLPFEEK_01908 1.02e-183 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
ICLPFEEK_01909 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
ICLPFEEK_01910 6.47e-144 ywbG - - M - - - effector of murein hydrolase
ICLPFEEK_01911 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
ICLPFEEK_01912 4.83e-202 ywbI - - K - - - Transcriptional regulator
ICLPFEEK_01913 2.35e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ICLPFEEK_01914 5.18e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ICLPFEEK_01915 9.68e-313 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
ICLPFEEK_01916 3.09e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
ICLPFEEK_01917 1.03e-173 - - - S - - - Streptomycin biosynthesis protein StrF
ICLPFEEK_01918 7.5e-168 - - - H - - - Methionine biosynthesis protein MetW
ICLPFEEK_01920 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
ICLPFEEK_01921 5.1e-83 gtcA - - S - - - GtrA-like protein
ICLPFEEK_01922 6.52e-292 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICLPFEEK_01923 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
ICLPFEEK_01924 5.74e-48 ydaS - - S - - - membrane
ICLPFEEK_01925 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
ICLPFEEK_01926 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICLPFEEK_01927 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
ICLPFEEK_01928 8.22e-85 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
ICLPFEEK_01929 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
ICLPFEEK_01930 1.2e-106 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
ICLPFEEK_01931 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
ICLPFEEK_01932 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
ICLPFEEK_01933 2.32e-172 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
ICLPFEEK_01934 1.55e-72 - - - L - - - COG2963 Transposase and inactivated derivatives
ICLPFEEK_01935 7.25e-240 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICLPFEEK_01936 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
ICLPFEEK_01938 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
ICLPFEEK_01939 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_01940 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
ICLPFEEK_01941 3.52e-26 ywdA - - - - - - -
ICLPFEEK_01942 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
ICLPFEEK_01943 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
ICLPFEEK_01944 3.46e-116 ywdD - - - - - - -
ICLPFEEK_01946 1.52e-197 ywdF - - S - - - Glycosyltransferase like family 2
ICLPFEEK_01947 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICLPFEEK_01948 3.04e-62 ywdI - - S - - - Family of unknown function (DUF5327)
ICLPFEEK_01949 1.19e-294 ywdJ - - F - - - Xanthine uracil
ICLPFEEK_01950 3.75e-77 ywdK - - S - - - small membrane protein
ICLPFEEK_01951 1.49e-89 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
ICLPFEEK_01952 9.06e-184 spsA - - M - - - Spore Coat
ICLPFEEK_01953 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
ICLPFEEK_01954 5.29e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
ICLPFEEK_01955 9.93e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
ICLPFEEK_01956 3.01e-275 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
ICLPFEEK_01957 2.22e-177 spsF - - M ko:K07257 - ko00000 Spore Coat
ICLPFEEK_01958 2.97e-244 spsG - - M - - - Spore Coat
ICLPFEEK_01959 6.9e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ICLPFEEK_01960 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICLPFEEK_01961 2.86e-209 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ICLPFEEK_01962 8.08e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
ICLPFEEK_01963 2.28e-222 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_01964 1.48e-153 - - - S - - - ABC-2 family transporter protein
ICLPFEEK_01965 9.66e-110 - - - - - - - -
ICLPFEEK_01966 5.52e-61 - - - S - - - Putative adhesin
ICLPFEEK_01967 2.59e-162 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_01968 3.44e-211 - - - T - - - Histidine kinase
ICLPFEEK_01969 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
ICLPFEEK_01970 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
ICLPFEEK_01971 0.0 rocB - - E - - - arginine degradation protein
ICLPFEEK_01972 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
ICLPFEEK_01973 2.17e-268 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
ICLPFEEK_01974 4.24e-288 ywfA - - EGP - - - -transporter
ICLPFEEK_01975 1.4e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
ICLPFEEK_01976 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
ICLPFEEK_01977 8.05e-181 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_01978 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
ICLPFEEK_01979 1.41e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
ICLPFEEK_01980 1.33e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
ICLPFEEK_01981 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
ICLPFEEK_01982 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
ICLPFEEK_01983 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
ICLPFEEK_01984 1.85e-217 - - - S - - - Conserved hypothetical protein 698
ICLPFEEK_01985 3.89e-211 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_01986 1.58e-204 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
ICLPFEEK_01988 1.21e-230 - - - - - - - -
ICLPFEEK_01991 1.79e-216 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
ICLPFEEK_01992 8.51e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_01993 3.23e-121 - - - S - - - membrane
ICLPFEEK_01994 4.58e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
ICLPFEEK_01995 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
ICLPFEEK_01996 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
ICLPFEEK_01997 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
ICLPFEEK_01998 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
ICLPFEEK_01999 2.71e-316 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
ICLPFEEK_02000 1.02e-93 ywhA - - K - - - Transcriptional regulator
ICLPFEEK_02001 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
ICLPFEEK_02002 2.31e-154 ywhC - - S - - - Peptidase family M50
ICLPFEEK_02003 3.32e-124 ywhD - - S - - - YwhD family
ICLPFEEK_02004 7.67e-109 - - - - - - - -
ICLPFEEK_02005 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
ICLPFEEK_02006 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ICLPFEEK_02007 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
ICLPFEEK_02010 2.07e-101 - - - CP - - - Membrane
ICLPFEEK_02012 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
ICLPFEEK_02013 2.41e-45 - - - - - - - -
ICLPFEEK_02014 9.15e-41 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
ICLPFEEK_02016 1.16e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
ICLPFEEK_02017 1.99e-299 ywhK - - CO - - - amine dehydrogenase activity
ICLPFEEK_02018 5.69e-314 ywhL - - CO - - - amine dehydrogenase activity
ICLPFEEK_02020 1.14e-96 ywiB - - S - - - protein conserved in bacteria
ICLPFEEK_02021 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
ICLPFEEK_02022 1.05e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
ICLPFEEK_02023 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
ICLPFEEK_02024 2.72e-181 ywiC - - S - - - YwiC-like protein
ICLPFEEK_02025 2.49e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
ICLPFEEK_02026 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICLPFEEK_02027 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
ICLPFEEK_02028 8.29e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
ICLPFEEK_02029 1.45e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
ICLPFEEK_02030 1.05e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICLPFEEK_02031 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICLPFEEK_02032 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
ICLPFEEK_02033 7.93e-59 ywjC - - - - - - -
ICLPFEEK_02034 1.25e-238 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
ICLPFEEK_02035 2.18e-288 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
ICLPFEEK_02036 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
ICLPFEEK_02037 6.53e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ICLPFEEK_02038 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ICLPFEEK_02039 8.11e-121 ywjG - - S - - - Domain of unknown function (DUF2529)
ICLPFEEK_02040 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
ICLPFEEK_02041 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
ICLPFEEK_02042 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICLPFEEK_02043 3.9e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICLPFEEK_02044 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
ICLPFEEK_02045 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ICLPFEEK_02046 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
ICLPFEEK_02047 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
ICLPFEEK_02048 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
ICLPFEEK_02049 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
ICLPFEEK_02050 1.04e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
ICLPFEEK_02051 9.07e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICLPFEEK_02052 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICLPFEEK_02053 4.19e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ICLPFEEK_02055 7.26e-80 ywlA - - S - - - Uncharacterised protein family (UPF0715)
ICLPFEEK_02056 2.05e-156 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
ICLPFEEK_02057 5.15e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
ICLPFEEK_02058 6.77e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ICLPFEEK_02059 1.17e-119 mntP - - P - - - Probably functions as a manganese efflux pump
ICLPFEEK_02060 2.08e-101 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICLPFEEK_02061 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
ICLPFEEK_02062 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
ICLPFEEK_02063 3.07e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICLPFEEK_02064 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICLPFEEK_02065 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
ICLPFEEK_02066 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
ICLPFEEK_02067 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICLPFEEK_02068 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICLPFEEK_02069 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICLPFEEK_02070 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICLPFEEK_02071 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICLPFEEK_02072 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICLPFEEK_02073 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
ICLPFEEK_02074 1.76e-118 ywmA - - - - - - -
ICLPFEEK_02075 2.25e-45 ywzB - - S - - - membrane
ICLPFEEK_02076 1.44e-175 ywmB - - S - - - TATA-box binding
ICLPFEEK_02077 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICLPFEEK_02078 3.47e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
ICLPFEEK_02079 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
ICLPFEEK_02080 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
ICLPFEEK_02082 1.1e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ICLPFEEK_02083 1.31e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ICLPFEEK_02084 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
ICLPFEEK_02085 3.66e-108 ywmF - - S - - - Peptidase M50
ICLPFEEK_02086 2.51e-18 csbD - - K - - - CsbD-like
ICLPFEEK_02087 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
ICLPFEEK_02088 1.85e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
ICLPFEEK_02089 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
ICLPFEEK_02090 1.08e-88 ywnA - - K - - - Transcriptional regulator
ICLPFEEK_02091 6.44e-158 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
ICLPFEEK_02092 2.4e-80 ywnC - - S - - - Family of unknown function (DUF5362)
ICLPFEEK_02093 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICLPFEEK_02094 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
ICLPFEEK_02096 4.77e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
ICLPFEEK_02097 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
ICLPFEEK_02098 8.06e-96 ywnJ - - S - - - VanZ like family
ICLPFEEK_02099 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
ICLPFEEK_02100 2.09e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
ICLPFEEK_02101 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
ICLPFEEK_02102 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
ICLPFEEK_02103 1.37e-133 yjgF - - Q - - - Isochorismatase family
ICLPFEEK_02104 1.98e-312 ywoD - - EGP - - - Major facilitator superfamily
ICLPFEEK_02105 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
ICLPFEEK_02106 2.89e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_02107 3.58e-93 ywoH - - K - - - transcriptional
ICLPFEEK_02108 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
ICLPFEEK_02109 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
ICLPFEEK_02110 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
ICLPFEEK_02111 1.14e-188 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
ICLPFEEK_02112 8.07e-259 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
ICLPFEEK_02113 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICLPFEEK_02114 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ICLPFEEK_02115 9.16e-91 ywpF - - S - - - YwpF-like protein
ICLPFEEK_02116 4.49e-82 ywpG - - - - - - -
ICLPFEEK_02117 1.79e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
ICLPFEEK_02118 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
ICLPFEEK_02119 9.52e-205 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
ICLPFEEK_02120 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
ICLPFEEK_02121 0.0 ywqB - - S - - - SWIM zinc finger
ICLPFEEK_02122 1.74e-21 - - - - - - - -
ICLPFEEK_02123 3.53e-152 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
ICLPFEEK_02124 2.69e-158 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
ICLPFEEK_02125 7.76e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
ICLPFEEK_02126 9.43e-316 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICLPFEEK_02127 1.84e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
ICLPFEEK_02130 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
ICLPFEEK_02131 0.0 ywqJ - - S - - - Pre-toxin TG
ICLPFEEK_02132 2.05e-66 - - - - - - - -
ICLPFEEK_02133 4.55e-121 - - - - - - - -
ICLPFEEK_02134 1.34e-95 - - - S - - - LXG domain of WXG superfamily
ICLPFEEK_02135 6.63e-137 - - - S - - - Domain of unknown function (DUF1851)
ICLPFEEK_02136 2.28e-63 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
ICLPFEEK_02137 9.61e-121 - - - - - - - -
ICLPFEEK_02138 4.5e-175 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
ICLPFEEK_02139 8.99e-116 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
ICLPFEEK_02140 4.38e-134 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
ICLPFEEK_02141 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
ICLPFEEK_02142 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
ICLPFEEK_02143 6.96e-145 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ICLPFEEK_02144 1.16e-31 - - - - - - - -
ICLPFEEK_02145 4.09e-273 cotH - - M ko:K06330 - ko00000 Spore Coat
ICLPFEEK_02146 1.22e-192 cotB - - - ko:K06325 - ko00000 -
ICLPFEEK_02147 3.43e-163 ywrJ - - - - - - -
ICLPFEEK_02148 1.27e-307 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ICLPFEEK_02149 5.35e-215 alsR - - K - - - LysR substrate binding domain
ICLPFEEK_02150 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
ICLPFEEK_02151 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
ICLPFEEK_02152 1.5e-124 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
ICLPFEEK_02153 2.49e-117 batE - - T - - - Sh3 type 3 domain protein
ICLPFEEK_02154 1.2e-208 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
ICLPFEEK_02155 1.87e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
ICLPFEEK_02156 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
ICLPFEEK_02157 5.83e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ICLPFEEK_02158 1.77e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICLPFEEK_02159 1.1e-230 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
ICLPFEEK_02160 2.25e-263 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
ICLPFEEK_02161 1.08e-247 - - - E - - - Spore germination protein
ICLPFEEK_02162 2.54e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
ICLPFEEK_02163 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
ICLPFEEK_02164 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
ICLPFEEK_02165 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
ICLPFEEK_02166 4.04e-29 ywtC - - - - - - -
ICLPFEEK_02167 2.85e-306 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
ICLPFEEK_02168 4.5e-80 yttA - - S - - - Pfam Transposase IS66
ICLPFEEK_02169 3.88e-204 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
ICLPFEEK_02170 9.77e-231 ywtF_2 - - K - - - Transcriptional regulator
ICLPFEEK_02171 4.54e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ICLPFEEK_02172 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
ICLPFEEK_02173 1.09e-274 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
ICLPFEEK_02174 4.65e-256 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
ICLPFEEK_02175 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
ICLPFEEK_02176 2.43e-243 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
ICLPFEEK_02177 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICLPFEEK_02178 1.57e-280 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ICLPFEEK_02179 6.38e-184 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ICLPFEEK_02180 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
ICLPFEEK_02181 0.0 - - - M - - - Glycosyltransferase like family 2
ICLPFEEK_02182 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ICLPFEEK_02183 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
ICLPFEEK_02184 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
ICLPFEEK_02185 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
ICLPFEEK_02186 1.88e-272 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICLPFEEK_02187 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
ICLPFEEK_02188 3.22e-65 - - - - - - - -
ICLPFEEK_02189 0.0 lytB - - D - - - Stage II sporulation protein
ICLPFEEK_02190 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
ICLPFEEK_02191 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
ICLPFEEK_02192 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICLPFEEK_02193 7.03e-289 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
ICLPFEEK_02194 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICLPFEEK_02195 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
ICLPFEEK_02196 8.95e-151 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
ICLPFEEK_02197 6.92e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
ICLPFEEK_02198 1.2e-305 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
ICLPFEEK_02199 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
ICLPFEEK_02200 2.6e-240 yvhJ - - K - - - Transcriptional regulator
ICLPFEEK_02201 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
ICLPFEEK_02202 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
ICLPFEEK_02203 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICLPFEEK_02204 8.81e-204 degV - - S - - - protein conserved in bacteria
ICLPFEEK_02205 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ICLPFEEK_02206 2.14e-58 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
ICLPFEEK_02207 2.13e-101 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
ICLPFEEK_02208 5.47e-98 yvyF - - S - - - flagellar protein
ICLPFEEK_02209 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
ICLPFEEK_02210 2.2e-105 yvyG - - NOU - - - FlgN protein
ICLPFEEK_02211 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
ICLPFEEK_02212 8.44e-209 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
ICLPFEEK_02213 5.9e-110 yviE - - - - - - -
ICLPFEEK_02214 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ICLPFEEK_02215 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICLPFEEK_02216 9.78e-173 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ICLPFEEK_02217 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ICLPFEEK_02218 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
ICLPFEEK_02219 1.1e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
ICLPFEEK_02220 1.35e-89 - - - - - - - -
ICLPFEEK_02221 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICLPFEEK_02222 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICLPFEEK_02223 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICLPFEEK_02224 4.82e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
ICLPFEEK_02225 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
ICLPFEEK_02226 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
ICLPFEEK_02227 7.34e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
ICLPFEEK_02228 9.32e-309 ywoF - - P - - - Right handed beta helix region
ICLPFEEK_02229 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
ICLPFEEK_02230 4.26e-74 swrA - - S - - - Swarming motility protein
ICLPFEEK_02231 9.15e-284 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICLPFEEK_02232 1.45e-298 yvkA - - P - - - -transporter
ICLPFEEK_02233 2.32e-144 yvkB - - K - - - Transcriptional regulator
ICLPFEEK_02234 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
ICLPFEEK_02235 2.59e-45 csbA - - S - - - protein conserved in bacteria
ICLPFEEK_02236 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICLPFEEK_02237 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ICLPFEEK_02238 1.78e-51 yvkN - - - - - - -
ICLPFEEK_02239 4.87e-66 yvlA - - - - - - -
ICLPFEEK_02240 5.54e-219 yvlB - - S - - - Putative adhesin
ICLPFEEK_02241 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
ICLPFEEK_02242 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
ICLPFEEK_02243 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
ICLPFEEK_02244 1.54e-136 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
ICLPFEEK_02245 1.05e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
ICLPFEEK_02246 9.42e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ICLPFEEK_02247 1.27e-290 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICLPFEEK_02248 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICLPFEEK_02249 1.84e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICLPFEEK_02250 8.12e-158 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
ICLPFEEK_02251 1.07e-115 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
ICLPFEEK_02252 3.56e-178 yvpB - - NU - - - protein conserved in bacteria
ICLPFEEK_02253 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ICLPFEEK_02254 1.83e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
ICLPFEEK_02255 9.92e-302 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICLPFEEK_02256 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
ICLPFEEK_02257 2.51e-150 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICLPFEEK_02258 4.81e-169 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ICLPFEEK_02259 2.39e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ICLPFEEK_02260 1.71e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
ICLPFEEK_02261 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
ICLPFEEK_02262 3.99e-158 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_02263 2.02e-247 sasA - - T - - - Histidine kinase
ICLPFEEK_02264 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
ICLPFEEK_02265 1.86e-204 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
ICLPFEEK_02266 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ICLPFEEK_02267 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
ICLPFEEK_02268 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
ICLPFEEK_02269 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
ICLPFEEK_02270 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
ICLPFEEK_02271 2.76e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
ICLPFEEK_02272 6.92e-184 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
ICLPFEEK_02273 5.54e-105 - - - M - - - Ribonuclease
ICLPFEEK_02274 2.51e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICLPFEEK_02275 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
ICLPFEEK_02276 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
ICLPFEEK_02277 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
ICLPFEEK_02278 1.32e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
ICLPFEEK_02279 0.0 - - - EGP - - - Sugar (and other) transporter
ICLPFEEK_02280 6.58e-276 yraM - - S - - - PrpF protein
ICLPFEEK_02281 3.34e-210 yraN - - K - - - Transcriptional regulator
ICLPFEEK_02282 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ICLPFEEK_02283 4.69e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
ICLPFEEK_02284 2.45e-286 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
ICLPFEEK_02285 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
ICLPFEEK_02287 3.92e-47 - - - - - - - -
ICLPFEEK_02288 0.0 - - - I - - - Pfam Lipase (class 3)
ICLPFEEK_02289 2.8e-16 - - - S - - - Protein of unknown function (DUF1433)
ICLPFEEK_02290 4.11e-57 - - - I - - - Pfam Lipase (class 3)
ICLPFEEK_02291 2.64e-54 - - - S - - - Protein of unknown function (DUF1433)
ICLPFEEK_02293 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
ICLPFEEK_02294 1.15e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICLPFEEK_02295 1.84e-146 yyaS - - S ko:K07149 - ko00000 Membrane
ICLPFEEK_02296 1.7e-128 ywjB - - H - - - RibD C-terminal domain
ICLPFEEK_02297 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
ICLPFEEK_02298 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
ICLPFEEK_02299 2.87e-156 epsA - - M ko:K19420 - ko00000 biosynthesis protein
ICLPFEEK_02300 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
ICLPFEEK_02301 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
ICLPFEEK_02302 4.01e-283 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
ICLPFEEK_02303 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
ICLPFEEK_02304 3.27e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
ICLPFEEK_02305 1.46e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
ICLPFEEK_02306 2.04e-252 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
ICLPFEEK_02307 4.18e-263 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
ICLPFEEK_02308 1.68e-255 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
ICLPFEEK_02309 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICLPFEEK_02310 9.52e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
ICLPFEEK_02311 6.08e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
ICLPFEEK_02312 3.31e-283 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
ICLPFEEK_02313 7.27e-243 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
ICLPFEEK_02314 9.82e-45 yvfG - - S - - - YvfG protein
ICLPFEEK_02315 7.14e-313 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
ICLPFEEK_02316 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
ICLPFEEK_02317 5.36e-157 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
ICLPFEEK_02318 4.23e-289 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICLPFEEK_02319 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
ICLPFEEK_02320 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
ICLPFEEK_02321 1.23e-173 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
ICLPFEEK_02322 2.89e-292 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
ICLPFEEK_02323 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
ICLPFEEK_02324 8.05e-197 gntR - - K - - - RpiR family transcriptional regulator
ICLPFEEK_02325 1.08e-215 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
ICLPFEEK_02326 1.55e-149 - - - S ko:K07149 - ko00000 Membrane
ICLPFEEK_02327 1.91e-235 yhjM - - K - - - Transcriptional regulator
ICLPFEEK_02328 0.0 - - - - - - - -
ICLPFEEK_02329 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
ICLPFEEK_02330 2.22e-204 yvbV - - EG - - - EamA-like transporter family
ICLPFEEK_02331 9.08e-202 yvbU - - K - - - Transcriptional regulator
ICLPFEEK_02333 5.33e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICLPFEEK_02334 2.33e-262 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
ICLPFEEK_02335 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ICLPFEEK_02337 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
ICLPFEEK_02338 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICLPFEEK_02339 2.8e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
ICLPFEEK_02340 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICLPFEEK_02341 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
ICLPFEEK_02342 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ICLPFEEK_02343 1.12e-308 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
ICLPFEEK_02344 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICLPFEEK_02345 1.19e-278 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
ICLPFEEK_02346 8.95e-222 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
ICLPFEEK_02347 1.41e-305 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICLPFEEK_02348 3.92e-192 - - - M - - - Protein involved in cellulose biosynthesis
ICLPFEEK_02349 2.89e-185 - - - C - - - WbqC-like protein family
ICLPFEEK_02350 1.9e-163 - - - S - - - GlcNAc-PI de-N-acetylase
ICLPFEEK_02351 1.02e-230 - - - - - - - -
ICLPFEEK_02352 1.14e-271 - - - EGP - - - Major facilitator Superfamily
ICLPFEEK_02353 1.11e-106 yvbK - - K - - - acetyltransferase
ICLPFEEK_02354 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
ICLPFEEK_02355 1.32e-157 yvbI - - M - - - Membrane
ICLPFEEK_02356 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
ICLPFEEK_02357 1.01e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
ICLPFEEK_02358 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
ICLPFEEK_02359 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
ICLPFEEK_02360 6.83e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ICLPFEEK_02361 2.64e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
ICLPFEEK_02362 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
ICLPFEEK_02363 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
ICLPFEEK_02364 2.39e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
ICLPFEEK_02365 6.83e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ICLPFEEK_02366 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
ICLPFEEK_02367 4.62e-163 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_02368 3.92e-163 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
ICLPFEEK_02369 1.44e-180 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
ICLPFEEK_02370 4.69e-159 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
ICLPFEEK_02371 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
ICLPFEEK_02372 2.97e-70 yvaP - - K - - - transcriptional
ICLPFEEK_02373 4.28e-97 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
ICLPFEEK_02374 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
ICLPFEEK_02375 1.64e-47 yvzC - - K - - - transcriptional
ICLPFEEK_02376 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
ICLPFEEK_02377 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
ICLPFEEK_02378 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ICLPFEEK_02379 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ICLPFEEK_02381 1.1e-70 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
ICLPFEEK_02382 4.79e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_02383 6.64e-211 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
ICLPFEEK_02384 1.57e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
ICLPFEEK_02385 7.17e-172 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
ICLPFEEK_02386 3.16e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
ICLPFEEK_02387 4.4e-158 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
ICLPFEEK_02388 1.42e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
ICLPFEEK_02389 1.56e-181 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
ICLPFEEK_02390 9.08e-235 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICLPFEEK_02391 1.49e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
ICLPFEEK_02392 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICLPFEEK_02393 4.33e-189 - - - S ko:K07045 - ko00000 Amidohydrolase
ICLPFEEK_02394 9.11e-92 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
ICLPFEEK_02395 9.17e-284 - - - EGP - - - Major Facilitator Superfamily
ICLPFEEK_02396 2.17e-209 - - - K - - - Helix-turn-helix XRE-family like proteins
ICLPFEEK_02397 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICLPFEEK_02398 8.97e-252 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
ICLPFEEK_02399 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
ICLPFEEK_02400 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
ICLPFEEK_02401 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
ICLPFEEK_02402 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
ICLPFEEK_02403 3.33e-140 bdbD - - O - - - Thioredoxin
ICLPFEEK_02404 1.83e-96 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
ICLPFEEK_02405 2.42e-193 - - - S - - - Metallo-peptidase family M12
ICLPFEEK_02406 2.24e-139 yvgT - - S - - - membrane
ICLPFEEK_02407 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
ICLPFEEK_02408 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ICLPFEEK_02409 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
ICLPFEEK_02410 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
ICLPFEEK_02411 9.69e-114 yvgO - - - - - - -
ICLPFEEK_02412 1.77e-200 yvgN - - S - - - reductase
ICLPFEEK_02413 4.36e-263 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
ICLPFEEK_02414 3.65e-251 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
ICLPFEEK_02415 4.97e-220 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
ICLPFEEK_02416 4.66e-257 - - - T - - - Histidine kinase
ICLPFEEK_02417 1.06e-148 yfiK - - K - - - Regulator
ICLPFEEK_02418 2.84e-127 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
ICLPFEEK_02419 2.89e-180 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
ICLPFEEK_02420 6e-215 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
ICLPFEEK_02421 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
ICLPFEEK_02422 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
ICLPFEEK_02423 1.06e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
ICLPFEEK_02424 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
ICLPFEEK_02425 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
ICLPFEEK_02426 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_02427 1.17e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_02428 2.4e-189 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
ICLPFEEK_02429 7.16e-90 yvrL - - S - - - Regulatory protein YrvL
ICLPFEEK_02430 1.08e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
ICLPFEEK_02431 1.88e-21 - - - S - - - YvrJ protein family
ICLPFEEK_02432 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
ICLPFEEK_02433 1.67e-50 - - - - - - - -
ICLPFEEK_02434 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_02435 0.0 yvrG - - T - - - Histidine kinase
ICLPFEEK_02436 2.28e-220 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
ICLPFEEK_02437 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_02438 1.16e-215 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
ICLPFEEK_02439 8.32e-233 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_02440 4.6e-290 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
ICLPFEEK_02441 3.23e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
ICLPFEEK_02442 7.41e-294 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_02443 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
ICLPFEEK_02444 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
ICLPFEEK_02445 2.12e-194 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
ICLPFEEK_02446 1.54e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
ICLPFEEK_02447 8.56e-248 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_02448 7.15e-140 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICLPFEEK_02449 1.04e-269 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
ICLPFEEK_02450 1.12e-246 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
ICLPFEEK_02451 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
ICLPFEEK_02452 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
ICLPFEEK_02453 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ICLPFEEK_02454 3.11e-201 yuxN - - K - - - Transcriptional regulator
ICLPFEEK_02455 4.63e-33 - - - - - - - -
ICLPFEEK_02456 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_02457 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_02458 8.31e-309 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICLPFEEK_02459 4.66e-105 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
ICLPFEEK_02460 5.7e-199 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_02461 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
ICLPFEEK_02462 3.77e-60 - - - S - - - YusW-like protein
ICLPFEEK_02463 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
ICLPFEEK_02464 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
ICLPFEEK_02465 1.78e-242 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICLPFEEK_02466 1.29e-179 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
ICLPFEEK_02467 1.3e-207 - - - K - - - Transcriptional regulator
ICLPFEEK_02468 2.44e-206 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
ICLPFEEK_02469 7.69e-171 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_02470 1.57e-89 yusQ - - S - - - Tautomerase enzyme
ICLPFEEK_02471 0.0 yusP - - P - - - Major facilitator superfamily
ICLPFEEK_02472 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
ICLPFEEK_02473 4.46e-72 yusN - - M - - - Coat F domain
ICLPFEEK_02474 2.25e-58 - - - - - - - -
ICLPFEEK_02475 1.12e-216 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
ICLPFEEK_02476 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
ICLPFEEK_02477 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
ICLPFEEK_02478 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
ICLPFEEK_02479 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
ICLPFEEK_02480 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
ICLPFEEK_02481 7.61e-56 yusG - - S - - - Protein of unknown function (DUF2553)
ICLPFEEK_02482 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
ICLPFEEK_02483 1.64e-72 yusE - - CO - - - Thioredoxin
ICLPFEEK_02484 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
ICLPFEEK_02485 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICLPFEEK_02486 1.46e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
ICLPFEEK_02487 4.46e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
ICLPFEEK_02488 8.85e-85 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICLPFEEK_02489 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
ICLPFEEK_02490 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
ICLPFEEK_02491 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICLPFEEK_02492 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
ICLPFEEK_02493 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
ICLPFEEK_02494 5.3e-203 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
ICLPFEEK_02495 2.94e-111 yncE - - S - - - Protein of unknown function (DUF2691)
ICLPFEEK_02496 7.94e-168 - - - Q - - - ubiE/COQ5 methyltransferase family
ICLPFEEK_02497 4.91e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
ICLPFEEK_02498 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
ICLPFEEK_02501 2.01e-213 - - - K - - - helix_turn_helix, mercury resistance
ICLPFEEK_02502 2.84e-239 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
ICLPFEEK_02503 1.36e-315 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
ICLPFEEK_02504 5.26e-203 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
ICLPFEEK_02505 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
ICLPFEEK_02506 2.63e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
ICLPFEEK_02507 5.89e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
ICLPFEEK_02508 1.41e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
ICLPFEEK_02509 2.46e-218 bsn - - L - - - Ribonuclease
ICLPFEEK_02510 1.3e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
ICLPFEEK_02511 2.64e-305 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
ICLPFEEK_02512 4.47e-276 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_02514 6.36e-97 - - - - - - - -
ICLPFEEK_02515 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
ICLPFEEK_02516 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
ICLPFEEK_02517 7.74e-83 - - - S - - - phosphoglycolate phosphatase activity
ICLPFEEK_02518 1.54e-218 yunF - - S - - - Protein of unknown function DUF72
ICLPFEEK_02519 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
ICLPFEEK_02520 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
ICLPFEEK_02521 2.87e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
ICLPFEEK_02522 1e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
ICLPFEEK_02523 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ICLPFEEK_02524 3.71e-62 yutD - - S - - - protein conserved in bacteria
ICLPFEEK_02525 3.25e-97 yutE - - S - - - Protein of unknown function DUF86
ICLPFEEK_02526 4.31e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ICLPFEEK_02527 2.59e-110 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
ICLPFEEK_02528 5.4e-251 yutH - - S - - - Spore coat protein
ICLPFEEK_02529 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
ICLPFEEK_02530 1.19e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ICLPFEEK_02531 4.08e-218 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ICLPFEEK_02532 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
ICLPFEEK_02533 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
ICLPFEEK_02534 8.37e-76 yuzD - - S - - - protein conserved in bacteria
ICLPFEEK_02535 1.46e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
ICLPFEEK_02536 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
ICLPFEEK_02537 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICLPFEEK_02538 5.54e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICLPFEEK_02539 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
ICLPFEEK_02540 3.83e-179 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_02541 5.25e-125 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
ICLPFEEK_02543 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
ICLPFEEK_02545 4.11e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
ICLPFEEK_02546 5.08e-94 - - - CP - - - Membrane
ICLPFEEK_02547 5.68e-40 - - - - - - - -
ICLPFEEK_02548 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICLPFEEK_02550 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
ICLPFEEK_02551 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
ICLPFEEK_02552 8.54e-46 yuiB - - S - - - Putative membrane protein
ICLPFEEK_02553 7.23e-155 yuiC - - S - - - protein conserved in bacteria
ICLPFEEK_02554 2.47e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
ICLPFEEK_02555 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICLPFEEK_02556 2.01e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
ICLPFEEK_02557 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
ICLPFEEK_02558 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
ICLPFEEK_02559 1.53e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
ICLPFEEK_02560 1.1e-174 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLPFEEK_02561 4.07e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
ICLPFEEK_02562 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
ICLPFEEK_02563 5.21e-225 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
ICLPFEEK_02564 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_02565 2.82e-48 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
ICLPFEEK_02566 1.84e-172 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
ICLPFEEK_02567 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
ICLPFEEK_02568 3.81e-294 yukF - - QT - - - Transcriptional regulator
ICLPFEEK_02569 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
ICLPFEEK_02570 9.1e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
ICLPFEEK_02571 3.38e-277 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
ICLPFEEK_02572 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
ICLPFEEK_02573 0.0 yueB - - S - - - type VII secretion protein EsaA
ICLPFEEK_02574 1.38e-102 yueC - - S - - - Family of unknown function (DUF5383)
ICLPFEEK_02575 8.67e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_02576 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
ICLPFEEK_02577 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
ICLPFEEK_02578 1.14e-239 yueF - - S - - - transporter activity
ICLPFEEK_02579 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
ICLPFEEK_02580 5.46e-51 yueH - - S - - - YueH-like protein
ICLPFEEK_02581 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
ICLPFEEK_02582 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
ICLPFEEK_02583 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICLPFEEK_02584 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
ICLPFEEK_02585 7.9e-72 yuzC - - - - - - -
ICLPFEEK_02586 2.66e-11 - - - S - - - DegQ (SacQ) family
ICLPFEEK_02587 6.39e-199 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
ICLPFEEK_02589 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_02590 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICLPFEEK_02591 1.45e-85 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
ICLPFEEK_02592 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
ICLPFEEK_02593 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICLPFEEK_02594 6.08e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICLPFEEK_02595 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICLPFEEK_02596 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICLPFEEK_02597 5.39e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICLPFEEK_02598 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
ICLPFEEK_02600 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
ICLPFEEK_02601 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
ICLPFEEK_02602 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_02603 1.74e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
ICLPFEEK_02604 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
ICLPFEEK_02605 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
ICLPFEEK_02606 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
ICLPFEEK_02607 1.85e-95 yuxK - - S - - - protein conserved in bacteria
ICLPFEEK_02608 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
ICLPFEEK_02609 2.25e-264 yuxJ - - EGP - - - Major facilitator superfamily
ICLPFEEK_02610 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
ICLPFEEK_02611 2.05e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
ICLPFEEK_02612 7.71e-294 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_02613 8.16e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
ICLPFEEK_02614 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
ICLPFEEK_02615 9.89e-201 yugF - - I - - - Hydrolase
ICLPFEEK_02616 3.75e-109 alaR - - K - - - Transcriptional regulator
ICLPFEEK_02617 2.59e-270 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
ICLPFEEK_02618 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
ICLPFEEK_02619 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
ICLPFEEK_02620 4.92e-288 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
ICLPFEEK_02621 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
ICLPFEEK_02622 2.15e-152 ycaC - - Q - - - Isochorismatase family
ICLPFEEK_02623 6.81e-134 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
ICLPFEEK_02624 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
ICLPFEEK_02626 2.09e-95 yugN - - S - - - YugN-like family
ICLPFEEK_02627 8.37e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
ICLPFEEK_02628 2.44e-35 mstX - - S - - - Membrane-integrating protein Mistic
ICLPFEEK_02629 1.24e-22 - - - - - - - -
ICLPFEEK_02630 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
ICLPFEEK_02631 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
ICLPFEEK_02632 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
ICLPFEEK_02633 1.83e-101 yugU - - S - - - Uncharacterised protein family UPF0047
ICLPFEEK_02634 6.26e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
ICLPFEEK_02635 1.61e-55 - - - - - - - -
ICLPFEEK_02636 3.28e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
ICLPFEEK_02637 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
ICLPFEEK_02638 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
ICLPFEEK_02639 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
ICLPFEEK_02640 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
ICLPFEEK_02641 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
ICLPFEEK_02642 2.84e-239 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
ICLPFEEK_02643 6.02e-252 yubA - - S - - - transporter activity
ICLPFEEK_02644 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ICLPFEEK_02646 1.64e-72 yjcN - - - - - - -
ICLPFEEK_02647 5.74e-161 - - - G - - - Cupin
ICLPFEEK_02648 1.52e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICLPFEEK_02649 1.62e-194 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICLPFEEK_02650 2.6e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
ICLPFEEK_02651 2.03e-122 yuaB - - - - - - -
ICLPFEEK_02652 3.51e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
ICLPFEEK_02653 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
ICLPFEEK_02654 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
ICLPFEEK_02655 1.67e-141 - - - S - - - MOSC domain
ICLPFEEK_02656 4.6e-108 yuaE - - S - - - DinB superfamily
ICLPFEEK_02657 1.68e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
ICLPFEEK_02658 1.6e-279 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
ICLPFEEK_02659 1.46e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
ICLPFEEK_02660 5.49e-282 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
ICLPFEEK_02661 1.27e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICLPFEEK_02662 8.07e-233 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
ICLPFEEK_02663 1.69e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
ICLPFEEK_02664 1e-290 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
ICLPFEEK_02665 1.87e-223 ybaS - - S - - - Na -dependent transporter
ICLPFEEK_02666 4.6e-151 ybbA - - S ko:K07017 - ko00000 Putative esterase
ICLPFEEK_02667 7.1e-230 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_02668 2.19e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_02669 2.1e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
ICLPFEEK_02670 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
ICLPFEEK_02671 3.46e-304 ybbC - - S - - - protein conserved in bacteria
ICLPFEEK_02672 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
ICLPFEEK_02673 1.95e-316 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
ICLPFEEK_02674 1.83e-313 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_02675 1.2e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ICLPFEEK_02676 3.15e-113 ybbJ - - J - - - acetyltransferase
ICLPFEEK_02677 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
ICLPFEEK_02683 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
ICLPFEEK_02684 1.11e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
ICLPFEEK_02685 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICLPFEEK_02686 1.64e-303 ybbR - - S - - - protein conserved in bacteria
ICLPFEEK_02687 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICLPFEEK_02688 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ICLPFEEK_02689 1.64e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
ICLPFEEK_02690 1.27e-141 - - - S - - - ABC-2 family transporter protein
ICLPFEEK_02691 7.92e-35 ybdN - - - - - - -
ICLPFEEK_02693 2.14e-163 - - - T ko:K11630 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_02694 3.07e-240 - - - T ko:K19168 - ko00000,ko02048 Histidine kinase
ICLPFEEK_02695 3.96e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_02696 0.0 - - - V ko:K02004,ko:K11632 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
ICLPFEEK_02697 4.5e-15 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICLPFEEK_02698 3.09e-208 dkgB - - S - - - Aldo/keto reductase family
ICLPFEEK_02699 7.37e-136 yxaC - - M - - - effector of murein hydrolase
ICLPFEEK_02700 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
ICLPFEEK_02701 3.52e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
ICLPFEEK_02702 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
ICLPFEEK_02703 7.56e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
ICLPFEEK_02704 1.99e-261 - - - T - - - COG4585 Signal transduction histidine kinase
ICLPFEEK_02705 5.23e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
ICLPFEEK_02706 3.5e-220 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
ICLPFEEK_02707 1.8e-269 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
ICLPFEEK_02708 7.79e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
ICLPFEEK_02709 2.34e-35 - - - - - - - -
ICLPFEEK_02710 2.68e-105 - - - S - - - Domain of unknown function (DUF4879)
ICLPFEEK_02711 1.75e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
ICLPFEEK_02712 1.42e-150 yqeB - - - - - - -
ICLPFEEK_02713 7.84e-55 ybyB - - - - - - -
ICLPFEEK_02714 0.0 ybeC - - E - - - amino acid
ICLPFEEK_02717 5.14e-22 - - - S - - - Protein of unknown function (DUF2651)
ICLPFEEK_02718 1.04e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
ICLPFEEK_02719 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
ICLPFEEK_02720 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
ICLPFEEK_02721 2.02e-267 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
ICLPFEEK_02723 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
ICLPFEEK_02724 2.44e-45 - - - - - - - -
ICLPFEEK_02725 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
ICLPFEEK_02726 4.68e-259 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
ICLPFEEK_02727 9.69e-273 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICLPFEEK_02728 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICLPFEEK_02729 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
ICLPFEEK_02730 7.49e-195 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
ICLPFEEK_02731 1.09e-57 ybfN - - - - - - -
ICLPFEEK_02732 3.47e-246 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
ICLPFEEK_02733 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICLPFEEK_02734 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
ICLPFEEK_02735 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
ICLPFEEK_02736 6.39e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
ICLPFEEK_02737 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
ICLPFEEK_02738 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
ICLPFEEK_02739 1.6e-281 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_02740 1e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
ICLPFEEK_02741 5.89e-36 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
ICLPFEEK_02742 4.47e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICLPFEEK_02743 8.46e-146 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
ICLPFEEK_02744 7.8e-238 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
ICLPFEEK_02745 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
ICLPFEEK_02746 3.92e-76 ydfQ - - CO - - - Thioredoxin
ICLPFEEK_02747 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
ICLPFEEK_02748 1.33e-104 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
ICLPFEEK_02749 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
ICLPFEEK_02750 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
ICLPFEEK_02751 8.93e-163 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICLPFEEK_02752 1.25e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ICLPFEEK_02753 7.62e-270 ycbU - - E - - - Selenocysteine lyase
ICLPFEEK_02754 2.61e-315 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
ICLPFEEK_02755 1.54e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
ICLPFEEK_02756 1.24e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
ICLPFEEK_02757 9.81e-149 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
ICLPFEEK_02758 2.04e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
ICLPFEEK_02759 4.79e-222 yccK - - C - - - Aldo keto reductase
ICLPFEEK_02760 3.39e-228 ycdA - - S - - - Domain of unknown function (DUF5105)
ICLPFEEK_02761 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
ICLPFEEK_02762 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
ICLPFEEK_02763 6.25e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
ICLPFEEK_02764 2.45e-249 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
ICLPFEEK_02765 9.39e-183 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
ICLPFEEK_02766 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
ICLPFEEK_02767 4.44e-215 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
ICLPFEEK_02768 6.92e-171 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
ICLPFEEK_02769 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
ICLPFEEK_02770 1.2e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICLPFEEK_02771 2.86e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
ICLPFEEK_02772 3.63e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
ICLPFEEK_02773 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
ICLPFEEK_02774 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
ICLPFEEK_02775 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
ICLPFEEK_02776 1.17e-246 yceH - - P - - - Belongs to the TelA family
ICLPFEEK_02777 1.1e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
ICLPFEEK_02778 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
ICLPFEEK_02779 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
ICLPFEEK_02780 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
ICLPFEEK_02781 5.82e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
ICLPFEEK_02782 8.03e-294 ycgA - - S - - - Membrane
ICLPFEEK_02783 1.32e-107 ycgB - - - - - - -
ICLPFEEK_02784 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
ICLPFEEK_02785 1.39e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
ICLPFEEK_02786 0.0 mdr - - EGP - - - the major facilitator superfamily
ICLPFEEK_02787 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
ICLPFEEK_02788 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
ICLPFEEK_02789 4.54e-196 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
ICLPFEEK_02790 5.64e-315 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
ICLPFEEK_02791 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
ICLPFEEK_02792 5.46e-193 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ICLPFEEK_02793 2.77e-06 - - - S - - - Bacillus cereus group antimicrobial protein
ICLPFEEK_02794 4.05e-142 tmrB - - S - - - AAA domain
ICLPFEEK_02795 7.21e-193 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
ICLPFEEK_02796 1.66e-304 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_02797 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ICLPFEEK_02798 2.41e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
ICLPFEEK_02799 2.23e-191 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
ICLPFEEK_02800 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
ICLPFEEK_02801 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
ICLPFEEK_02802 3.14e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICLPFEEK_02803 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
ICLPFEEK_02804 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
ICLPFEEK_02805 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
ICLPFEEK_02806 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
ICLPFEEK_02807 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICLPFEEK_02808 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICLPFEEK_02809 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
ICLPFEEK_02810 2.09e-287 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
ICLPFEEK_02811 4.25e-291 yciC - - S - - - GTPases (G3E family)
ICLPFEEK_02812 7.79e-285 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
ICLPFEEK_02813 9.31e-97 yckC - - S - - - membrane
ICLPFEEK_02814 3.31e-68 - - - S - - - Protein of unknown function (DUF2680)
ICLPFEEK_02815 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
ICLPFEEK_02816 5.81e-92 nin - - S - - - Competence protein J (ComJ)
ICLPFEEK_02817 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
ICLPFEEK_02818 2.67e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
ICLPFEEK_02819 3.82e-140 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
ICLPFEEK_02820 1.01e-84 hxlR - - K - - - transcriptional
ICLPFEEK_02821 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_02822 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_02823 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
ICLPFEEK_02824 3.05e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
ICLPFEEK_02825 0.0 - - - E - - - Aminotransferase class I and II
ICLPFEEK_02826 2.38e-86 - - - S - - - YcxB-like protein
ICLPFEEK_02828 8.2e-219 ycxC - - EG - - - EamA-like transporter family
ICLPFEEK_02829 0.0 ycxD - - K - - - GntR family transcriptional regulator
ICLPFEEK_02830 1.11e-168 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
ICLPFEEK_02831 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
ICLPFEEK_02832 8.3e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
ICLPFEEK_02833 3.03e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
ICLPFEEK_02834 2.8e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
ICLPFEEK_02835 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
ICLPFEEK_02836 1.46e-131 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
ICLPFEEK_02837 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
ICLPFEEK_02838 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
ICLPFEEK_02839 3.51e-102 yclD - - - - - - -
ICLPFEEK_02840 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
ICLPFEEK_02841 0.0 yclG - - M - - - Pectate lyase superfamily protein
ICLPFEEK_02843 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
ICLPFEEK_02844 1.3e-305 gerKC - - S ko:K06297 - ko00000 spore germination
ICLPFEEK_02845 7.92e-250 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
ICLPFEEK_02846 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICLPFEEK_02847 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICLPFEEK_02848 1.56e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
ICLPFEEK_02849 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
ICLPFEEK_02850 1.38e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_02851 6.14e-280 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
ICLPFEEK_02852 0.0 yxeQ - - S - - - MmgE/PrpD family
ICLPFEEK_02853 4.84e-160 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
ICLPFEEK_02854 0.0 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
ICLPFEEK_02855 9.08e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_02856 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
ICLPFEEK_02857 1.09e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
ICLPFEEK_02860 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
ICLPFEEK_02861 1.91e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_02862 3.45e-213 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICLPFEEK_02863 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_02864 1.18e-224 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
ICLPFEEK_02865 0.0 ycnB - - EGP - - - the major facilitator superfamily
ICLPFEEK_02866 3.14e-197 ycnC - - K - - - Transcriptional regulator
ICLPFEEK_02867 4.14e-176 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
ICLPFEEK_02868 3.39e-60 ycnE - - S - - - Monooxygenase
ICLPFEEK_02869 1.37e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
ICLPFEEK_02870 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICLPFEEK_02871 2.65e-288 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICLPFEEK_02872 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ICLPFEEK_02873 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
ICLPFEEK_02874 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_02875 2.05e-131 ycnI - - S - - - protein conserved in bacteria
ICLPFEEK_02876 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
ICLPFEEK_02877 1.49e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
ICLPFEEK_02878 9.6e-73 - - - - - - - -
ICLPFEEK_02879 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
ICLPFEEK_02880 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
ICLPFEEK_02881 4.59e-270 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
ICLPFEEK_02882 1.74e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
ICLPFEEK_02884 4.66e-178 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
ICLPFEEK_02885 6.12e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
ICLPFEEK_02886 3.24e-272 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
ICLPFEEK_02887 2.15e-195 ycsI - - S - - - Belongs to the D-glutamate cyclase family
ICLPFEEK_02888 4.86e-177 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
ICLPFEEK_02889 7.58e-244 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
ICLPFEEK_02890 2.93e-170 kipR - - K - - - Transcriptional regulator
ICLPFEEK_02891 5.71e-152 ycsK - - E - - - anatomical structure formation involved in morphogenesis
ICLPFEEK_02893 5.95e-75 yczJ - - S - - - biosynthesis
ICLPFEEK_02894 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
ICLPFEEK_02895 7.67e-223 ycsN - - S - - - Oxidoreductase
ICLPFEEK_02896 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
ICLPFEEK_02897 0.0 ydaB - - IQ - - - acyl-CoA ligase
ICLPFEEK_02898 9.37e-208 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_02899 1.17e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
ICLPFEEK_02900 1.07e-153 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ICLPFEEK_02901 1.83e-101 ydaG - - S - - - general stress protein
ICLPFEEK_02902 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
ICLPFEEK_02903 5.59e-64 ydzA - - EGP - - - Domain of unknown function (DUF3817)
ICLPFEEK_02904 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
ICLPFEEK_02905 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICLPFEEK_02906 4.53e-264 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
ICLPFEEK_02907 7.99e-191 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
ICLPFEEK_02908 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
ICLPFEEK_02909 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
ICLPFEEK_02910 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
ICLPFEEK_02911 0.0 ydaO - - E - - - amino acid
ICLPFEEK_02912 3.34e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
ICLPFEEK_02913 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
ICLPFEEK_02914 1.45e-98 - - - K - - - acetyltransferase
ICLPFEEK_02916 6.3e-60 - - - - - - - -
ICLPFEEK_02917 5.37e-271 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
ICLPFEEK_02919 5.42e-12 - - - - - - - -
ICLPFEEK_02921 7.56e-116 - - - - - - - -
ICLPFEEK_02922 1.79e-131 - - - - - - - -
ICLPFEEK_02923 1.29e-54 - - - - - - - -
ICLPFEEK_02924 1.6e-289 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
ICLPFEEK_02926 1.95e-45 ydaT - - - - - - -
ICLPFEEK_02927 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
ICLPFEEK_02928 7.05e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
ICLPFEEK_02929 2.29e-183 ydbA - - P - - - EcsC protein family
ICLPFEEK_02930 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
ICLPFEEK_02931 7.98e-86 ydbB - - G - - - Cupin domain
ICLPFEEK_02932 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
ICLPFEEK_02933 1.64e-199 ydbD - - P ko:K07217 - ko00000 Catalase
ICLPFEEK_02934 4.65e-256 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
ICLPFEEK_02935 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
ICLPFEEK_02936 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
ICLPFEEK_02937 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICLPFEEK_02938 8.61e-231 ydbI - - S - - - AI-2E family transporter
ICLPFEEK_02939 1.67e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_02940 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ICLPFEEK_02941 2.29e-70 ydbL - - - - - - -
ICLPFEEK_02942 3.47e-267 ydbM - - I - - - acyl-CoA dehydrogenase
ICLPFEEK_02943 1.13e-15 - - - S - - - Fur-regulated basic protein B
ICLPFEEK_02944 6.58e-14 - - - S - - - Fur-regulated basic protein A
ICLPFEEK_02945 2.8e-79 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICLPFEEK_02946 8.5e-116 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICLPFEEK_02947 2.25e-74 ydbP - - CO - - - Thioredoxin
ICLPFEEK_02948 5.31e-259 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
ICLPFEEK_02949 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ICLPFEEK_02950 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ICLPFEEK_02951 6.83e-109 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
ICLPFEEK_02952 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
ICLPFEEK_02953 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
ICLPFEEK_02954 5.81e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ICLPFEEK_02955 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
ICLPFEEK_02956 7.21e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICLPFEEK_02957 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
ICLPFEEK_02958 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
ICLPFEEK_02959 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
ICLPFEEK_02960 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
ICLPFEEK_02961 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
ICLPFEEK_02962 2.17e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
ICLPFEEK_02963 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
ICLPFEEK_02964 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
ICLPFEEK_02965 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICLPFEEK_02966 4.22e-143 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
ICLPFEEK_02967 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
ICLPFEEK_02968 1.78e-21 - - - - - - - -
ICLPFEEK_02969 1.81e-77 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
ICLPFEEK_02977 3.44e-127 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
ICLPFEEK_02978 4.71e-98 - - - S - - - SnoaL-like polyketide cyclase
ICLPFEEK_02979 5.42e-182 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
ICLPFEEK_02980 1.16e-93 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
ICLPFEEK_02981 2.73e-201 - - - S - - - Serine aminopeptidase, S33
ICLPFEEK_02982 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
ICLPFEEK_02983 5.16e-66 ohrR - - K - - - Transcriptional regulator
ICLPFEEK_02984 8.64e-112 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
ICLPFEEK_02985 4.48e-98 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
ICLPFEEK_02986 1.59e-85 - - - S - - - YjbR
ICLPFEEK_02987 3.48e-98 ywnA - - K - - - Transcriptional regulator
ICLPFEEK_02988 1.4e-147 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
ICLPFEEK_02989 7.04e-133 - - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
ICLPFEEK_02990 2.48e-173 - - - C ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
ICLPFEEK_02991 2.13e-233 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
ICLPFEEK_02992 1.62e-227 - - - C - - - COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
ICLPFEEK_02993 6.06e-75 - - - K - - - Transcriptional regulator
ICLPFEEK_02994 1.13e-252 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
ICLPFEEK_02995 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
ICLPFEEK_02996 2.51e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
ICLPFEEK_02997 2.63e-53 yrkD - - S - - - protein conserved in bacteria
ICLPFEEK_02998 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
ICLPFEEK_02999 1.17e-84 - - - P - - - Rhodanese Homology Domain
ICLPFEEK_03000 3.94e-133 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
ICLPFEEK_03001 4.1e-254 yrkH - - P - - - Rhodanese Homology Domain
ICLPFEEK_03002 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
ICLPFEEK_03003 2.16e-167 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
ICLPFEEK_03004 9.82e-164 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
ICLPFEEK_03005 1.18e-139 - - - S - - - Protein of unknown function (DUF2812)
ICLPFEEK_03006 9.96e-69 - - - K - - - Transcriptional regulator PadR-like family
ICLPFEEK_03007 1.18e-222 ybfA - - K - - - FR47-like protein
ICLPFEEK_03008 4.93e-303 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_03009 1.84e-236 - - - S - - - Patatin-like phospholipase
ICLPFEEK_03010 4.3e-111 - - - S - - - DinB superfamily
ICLPFEEK_03011 1.48e-86 - - - G - - - Cupin domain
ICLPFEEK_03014 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
ICLPFEEK_03015 5.28e-104 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICLPFEEK_03016 1.17e-219 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
ICLPFEEK_03017 2.69e-257 trkA - - P ko:K07222 - ko00000 Oxidoreductase
ICLPFEEK_03019 4.01e-132 yrkC - - G - - - Cupin domain
ICLPFEEK_03021 2.2e-116 ykkA - - S - - - Protein of unknown function (DUF664)
ICLPFEEK_03022 6.3e-192 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
ICLPFEEK_03024 6.11e-256 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
ICLPFEEK_03025 2.23e-75 ydeH - - - - - - -
ICLPFEEK_03026 4.51e-111 - - - F - - - nucleoside 2-deoxyribosyltransferase
ICLPFEEK_03027 3.94e-250 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICLPFEEK_03028 9.13e-191 - - - Q - - - ubiE/COQ5 methyltransferase family
ICLPFEEK_03029 5.46e-193 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
ICLPFEEK_03030 1.69e-298 - - - G - - - Haloacid dehalogenase-like hydrolase
ICLPFEEK_03031 8.2e-219 - - - S - - - Sodium Bile acid symporter family
ICLPFEEK_03032 6.64e-260 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
ICLPFEEK_03033 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
ICLPFEEK_03034 3.51e-291 nhaC_1 - - C - - - antiporter
ICLPFEEK_03035 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
ICLPFEEK_03036 4.37e-148 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
ICLPFEEK_03038 3.6e-145 - - - I - - - Ribosomal RNA adenine dimethylase
ICLPFEEK_03039 1.06e-159 - - - T - - - Transcriptional regulator
ICLPFEEK_03040 9.62e-248 - - - T - - - COG0642 Signal transduction histidine kinase
ICLPFEEK_03041 7.73e-139 - - - S - - - SNARE associated Golgi protein
ICLPFEEK_03042 1.36e-253 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
ICLPFEEK_03043 1.2e-132 ydeS - - K - - - Transcriptional regulator
ICLPFEEK_03044 3.17e-203 ydeK - - EG - - - -transporter
ICLPFEEK_03045 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICLPFEEK_03046 1.25e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
ICLPFEEK_03047 3.54e-35 yraE - - - ko:K06440 - ko00000 -
ICLPFEEK_03048 1.29e-283 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
ICLPFEEK_03049 2.86e-85 yraF - - M - - - Spore coat protein
ICLPFEEK_03050 2.95e-50 yraG - - - ko:K06440 - ko00000 -
ICLPFEEK_03051 1.96e-281 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_03052 1.19e-143 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICLPFEEK_03053 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
ICLPFEEK_03054 1.04e-174 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
ICLPFEEK_03055 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
ICLPFEEK_03056 5.71e-131 ynaD - - J - - - Acetyltransferase (GNAT) domain
ICLPFEEK_03057 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
ICLPFEEK_03058 7.09e-251 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
ICLPFEEK_03059 8.22e-270 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
ICLPFEEK_03060 8.62e-292 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICLPFEEK_03061 2.73e-201 - - - K - - - Helix-turn-helix XRE-family like proteins
ICLPFEEK_03062 9e-158 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
ICLPFEEK_03063 2.62e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
ICLPFEEK_03064 1.29e-196 bltR - - K - - - helix_turn_helix, mercury resistance
ICLPFEEK_03065 1.61e-194 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ICLPFEEK_03066 2.44e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
ICLPFEEK_03067 6.92e-190 - - - Q - - - ubiE/COQ5 methyltransferase family
ICLPFEEK_03068 3.44e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
ICLPFEEK_03069 2e-26 - 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
ICLPFEEK_03070 2.79e-155 ydhC - - K - - - FCD
ICLPFEEK_03071 4.77e-291 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ICLPFEEK_03074 0.0 pbpE - - V - - - Beta-lactamase
ICLPFEEK_03076 4.3e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
ICLPFEEK_03077 1.11e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
ICLPFEEK_03078 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
ICLPFEEK_03079 3.96e-155 - - - K ko:K05799 - ko00000,ko03000 FCD
ICLPFEEK_03080 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
ICLPFEEK_03081 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
ICLPFEEK_03082 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
ICLPFEEK_03083 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
ICLPFEEK_03084 0.0 ybeC - - E - - - amino acid
ICLPFEEK_03085 4.41e-214 ydhU - - P ko:K07217 - ko00000 Catalase
ICLPFEEK_03086 5.06e-113 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
ICLPFEEK_03087 2.83e-237 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
ICLPFEEK_03088 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ICLPFEEK_03093 2.25e-239 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ICLPFEEK_03094 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
ICLPFEEK_03095 1.02e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
ICLPFEEK_03096 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
ICLPFEEK_03097 3.92e-246 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICLPFEEK_03098 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
ICLPFEEK_03099 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
ICLPFEEK_03100 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ICLPFEEK_03101 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
ICLPFEEK_03102 8.18e-163 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICLPFEEK_03103 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
ICLPFEEK_03104 4.09e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
ICLPFEEK_03105 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICLPFEEK_03106 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ICLPFEEK_03107 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
ICLPFEEK_03110 8.34e-86 - - - - - - - -
ICLPFEEK_03111 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
ICLPFEEK_03112 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
ICLPFEEK_03113 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
ICLPFEEK_03114 2.29e-225 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
ICLPFEEK_03115 5.98e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
ICLPFEEK_03116 7.04e-149 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
ICLPFEEK_03117 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICLPFEEK_03118 8.16e-165 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
ICLPFEEK_03119 1.94e-224 ydjI - - S - - - virion core protein (lumpy skin disease virus)
ICLPFEEK_03120 0.0 oatA - - I - - - Acyltransferase family
ICLPFEEK_03121 1.68e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
ICLPFEEK_03122 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
ICLPFEEK_03123 1.74e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
ICLPFEEK_03124 3.92e-83 ydjM - - M - - - Lytic transglycolase
ICLPFEEK_03125 2.12e-196 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
ICLPFEEK_03127 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
ICLPFEEK_03128 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
ICLPFEEK_03129 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
ICLPFEEK_03130 3.04e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICLPFEEK_03131 2.39e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
ICLPFEEK_03132 6.89e-278 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
ICLPFEEK_03133 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
ICLPFEEK_03134 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
ICLPFEEK_03135 2.81e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
ICLPFEEK_03136 0.0 - - - S - - - Domain of unknown function (DUF4179)
ICLPFEEK_03137 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
ICLPFEEK_03138 1.42e-173 yebC - - M - - - Membrane
ICLPFEEK_03140 2.66e-120 yebE - - S - - - UPF0316 protein
ICLPFEEK_03141 6.56e-40 yebG - - S - - - NETI protein
ICLPFEEK_03142 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICLPFEEK_03143 3.9e-288 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICLPFEEK_03144 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICLPFEEK_03145 2.13e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
ICLPFEEK_03146 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICLPFEEK_03147 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICLPFEEK_03148 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICLPFEEK_03149 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICLPFEEK_03150 4.57e-245 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
ICLPFEEK_03151 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICLPFEEK_03152 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
ICLPFEEK_03153 1.85e-303 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
ICLPFEEK_03154 4.18e-34 - - - S - - - Protein of unknown function (DUF2892)
ICLPFEEK_03155 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
ICLPFEEK_03156 7.32e-248 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
ICLPFEEK_03157 2.03e-67 yerC - - S - - - protein conserved in bacteria
ICLPFEEK_03158 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
ICLPFEEK_03159 1.51e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ICLPFEEK_03160 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
ICLPFEEK_03161 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICLPFEEK_03162 2.74e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
ICLPFEEK_03163 5.83e-254 yerI - - S - - - homoserine kinase type II (protein kinase fold)
ICLPFEEK_03164 5.01e-159 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
ICLPFEEK_03165 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICLPFEEK_03166 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICLPFEEK_03167 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ICLPFEEK_03168 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICLPFEEK_03169 1.63e-199 yerO - - K - - - Transcriptional regulator
ICLPFEEK_03170 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICLPFEEK_03171 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ICLPFEEK_03172 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICLPFEEK_03173 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
ICLPFEEK_03174 4.67e-299 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
ICLPFEEK_03175 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
ICLPFEEK_03177 2.53e-286 - - - V ko:K07451 - ko00000,ko01000,ko02048 Domain of unknown function (DUF3578)
ICLPFEEK_03178 1.42e-118 - - - S - - - Protein of unknown function, DUF600
ICLPFEEK_03179 2.84e-108 - - - S - - - Protein of unknown function, DUF600
ICLPFEEK_03180 1.06e-110 - - - S - - - Protein of unknown function, DUF600
ICLPFEEK_03181 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
ICLPFEEK_03182 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
ICLPFEEK_03184 4.61e-61 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
ICLPFEEK_03185 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
ICLPFEEK_03186 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
ICLPFEEK_03187 3.17e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
ICLPFEEK_03188 5.92e-05 - - - - - - - -
ICLPFEEK_03189 8.99e-157 yetF - - S - - - membrane
ICLPFEEK_03190 5.49e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
ICLPFEEK_03191 2.27e-86 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICLPFEEK_03192 7.98e-200 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ICLPFEEK_03193 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
ICLPFEEK_03194 1.82e-73 - - - H - - - riboflavin kinase activity
ICLPFEEK_03195 1.54e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
ICLPFEEK_03196 2.08e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
ICLPFEEK_03197 2.19e-267 yetM - - CH - - - FAD binding domain
ICLPFEEK_03198 2.38e-252 yetN - - S - - - Protein of unknown function (DUF3900)
ICLPFEEK_03199 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
ICLPFEEK_03201 5.83e-67 - - - K - - - Winged helix DNA-binding domain
ICLPFEEK_03202 7.9e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
ICLPFEEK_03203 2.27e-163 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
ICLPFEEK_03204 4.77e-130 - - - S - - - protein homooligomerization
ICLPFEEK_03205 1.98e-167 - - - - - - - -
ICLPFEEK_03206 7.91e-247 - - - S - - - ATP diphosphatase activity
ICLPFEEK_03207 0.0 - - - S ko:K09136 - ko00000,ko03009 YcaO cyclodehydratase, ATP-ad Mg2+-binding
ICLPFEEK_03208 5.49e-196 - - - C - - - Nitroreductase family
ICLPFEEK_03209 3.67e-150 - - - S - - - CAAX protease self-immunity
ICLPFEEK_03210 7.44e-190 - 2.1.1.163, 2.1.1.201 - Q ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 methyltransferase
ICLPFEEK_03212 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
ICLPFEEK_03213 6.17e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
ICLPFEEK_03214 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
ICLPFEEK_03215 6.89e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
ICLPFEEK_03216 5.31e-287 yfnE - - S - - - Glycosyltransferase like family 2
ICLPFEEK_03217 1.46e-240 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
ICLPFEEK_03218 2.7e-278 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_03219 4.33e-315 yfnA - - E ko:K03294 - ko00000 amino acid
ICLPFEEK_03220 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ICLPFEEK_03221 2.85e-169 yfmS - - NT - - - chemotaxis protein
ICLPFEEK_03222 2.1e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
ICLPFEEK_03223 9.2e-270 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
ICLPFEEK_03224 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ICLPFEEK_03225 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
ICLPFEEK_03226 1.25e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
ICLPFEEK_03227 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ICLPFEEK_03228 3.91e-268 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
ICLPFEEK_03229 3.25e-26 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
ICLPFEEK_03230 1.19e-43 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
ICLPFEEK_03231 2.54e-243 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
ICLPFEEK_03232 4.44e-31 - - - S - - - Protein of unknown function (DUF3212)
ICLPFEEK_03233 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
ICLPFEEK_03234 8.27e-311 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
ICLPFEEK_03235 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
ICLPFEEK_03236 7.54e-41 - - - Q - - - PFAM Collagen triple helix
ICLPFEEK_03237 3.19e-117 - - - Q - - - PFAM Collagen triple helix
ICLPFEEK_03238 2.96e-188 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
ICLPFEEK_03239 2.34e-121 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
ICLPFEEK_03240 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
ICLPFEEK_03241 8.33e-156 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
ICLPFEEK_03242 8.33e-228 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
ICLPFEEK_03243 2.01e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
ICLPFEEK_03244 5.08e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
ICLPFEEK_03245 1.49e-279 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ICLPFEEK_03246 3.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
ICLPFEEK_03247 5.28e-160 yflK - - S - - - protein conserved in bacteria
ICLPFEEK_03248 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
ICLPFEEK_03249 1.98e-26 yflI - - - - - - -
ICLPFEEK_03250 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
ICLPFEEK_03251 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
ICLPFEEK_03252 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
ICLPFEEK_03253 7.03e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
ICLPFEEK_03254 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
ICLPFEEK_03255 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
ICLPFEEK_03256 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
ICLPFEEK_03257 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
ICLPFEEK_03258 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
ICLPFEEK_03259 3.27e-315 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_03260 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
ICLPFEEK_03261 2.89e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
ICLPFEEK_03262 1.45e-158 frp - - C - - - nitroreductase
ICLPFEEK_03263 6e-167 yibF - - S - - - YibE/F-like protein
ICLPFEEK_03264 8.4e-260 yibE - - S - - - YibE/F-like protein
ICLPFEEK_03266 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
ICLPFEEK_03267 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
ICLPFEEK_03268 1.58e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
ICLPFEEK_03269 6.12e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICLPFEEK_03270 1.82e-177 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
ICLPFEEK_03271 8.51e-253 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_03272 2.53e-42 yfkK - - S - - - Belongs to the UPF0435 family
ICLPFEEK_03273 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICLPFEEK_03274 1.29e-70 yfkI - - S - - - gas vesicle protein
ICLPFEEK_03275 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
ICLPFEEK_03276 6.71e-12 - - - - - - - -
ICLPFEEK_03277 2.61e-281 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_03278 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
ICLPFEEK_03279 5.66e-186 yfkD - - S - - - YfkD-like protein
ICLPFEEK_03280 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
ICLPFEEK_03281 2.06e-282 yfkA - - S - - - YfkB-like domain
ICLPFEEK_03282 7.99e-37 yfjT - - - - - - -
ICLPFEEK_03283 1.07e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
ICLPFEEK_03284 2.05e-195 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
ICLPFEEK_03286 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
ICLPFEEK_03287 7.59e-212 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ICLPFEEK_03288 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICLPFEEK_03289 2.97e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICLPFEEK_03290 1.42e-122 yfjM - - S - - - Psort location Cytoplasmic, score
ICLPFEEK_03291 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ICLPFEEK_03292 9.2e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ICLPFEEK_03293 6.13e-278 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICLPFEEK_03294 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ICLPFEEK_03295 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
ICLPFEEK_03296 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
ICLPFEEK_03297 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
ICLPFEEK_03298 2.69e-179 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
ICLPFEEK_03299 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
ICLPFEEK_03300 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
ICLPFEEK_03301 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
ICLPFEEK_03302 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
ICLPFEEK_03303 1.36e-82 yfiD3 - - S - - - DoxX
ICLPFEEK_03304 3.46e-207 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
ICLPFEEK_03305 2.03e-221 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ICLPFEEK_03306 5.62e-126 padR - - K - - - transcriptional
ICLPFEEK_03307 1.26e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
ICLPFEEK_03308 7.2e-241 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ICLPFEEK_03309 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
ICLPFEEK_03310 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
ICLPFEEK_03311 1.24e-132 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
ICLPFEEK_03312 0.0 yfiU - - EGP - - - the major facilitator superfamily
ICLPFEEK_03313 1.38e-108 yfiV - - K - - - transcriptional
ICLPFEEK_03314 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICLPFEEK_03315 3.35e-214 yfhB - - S - - - PhzF family
ICLPFEEK_03316 8.22e-138 yfhC - - C - - - nitroreductase
ICLPFEEK_03317 3.61e-34 yfhD - - S - - - YfhD-like protein
ICLPFEEK_03319 1.08e-217 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
ICLPFEEK_03320 3.14e-183 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
ICLPFEEK_03321 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
ICLPFEEK_03322 1.42e-268 yfhI - - EGP - - - -transporter
ICLPFEEK_03324 2.1e-217 mpr - - M - - - Belongs to the peptidase S1B family
ICLPFEEK_03325 3.12e-60 yfhJ - - S - - - WVELL protein
ICLPFEEK_03326 2.94e-124 yfhK - - T - - - Bacterial SH3 domain homologues
ICLPFEEK_03327 6.28e-59 yfhL - - S - - - SdpI/YhfL protein family
ICLPFEEK_03328 5.82e-220 - - - S - - - Alpha/beta hydrolase family
ICLPFEEK_03329 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
ICLPFEEK_03330 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
ICLPFEEK_03331 2.52e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
ICLPFEEK_03332 3.2e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
ICLPFEEK_03333 2.54e-50 yfhS - - - - - - -
ICLPFEEK_03334 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICLPFEEK_03335 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
ICLPFEEK_03336 1.4e-49 ygaB - - S - - - YgaB-like protein
ICLPFEEK_03337 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
ICLPFEEK_03338 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
ICLPFEEK_03339 1.58e-240 ygaE - - S - - - Membrane
ICLPFEEK_03340 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
ICLPFEEK_03341 3.41e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
ICLPFEEK_03342 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
ICLPFEEK_03343 4.67e-75 ygzB - - S - - - UPF0295 protein
ICLPFEEK_03344 2.75e-213 ygxA - - S - - - Nucleotidyltransferase-like
ICLPFEEK_03345 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICLPFEEK_03346 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICLPFEEK_03347 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
ICLPFEEK_03348 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICLPFEEK_03349 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
ICLPFEEK_03350 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ICLPFEEK_03351 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICLPFEEK_03352 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ICLPFEEK_03353 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICLPFEEK_03354 8.37e-145 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
ICLPFEEK_03355 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICLPFEEK_03356 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ICLPFEEK_03357 1.68e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
ICLPFEEK_03358 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
ICLPFEEK_03359 1.18e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
ICLPFEEK_03360 1.23e-190 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
ICLPFEEK_03361 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
ICLPFEEK_03362 1.86e-114 yhhY - - K - - - FR47-like protein
ICLPFEEK_03363 1.67e-225 yyaD - - S - - - Membrane
ICLPFEEK_03364 3.13e-46 yyzM - - S - - - protein conserved in bacteria
ICLPFEEK_03365 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICLPFEEK_03366 2.3e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ICLPFEEK_03367 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
ICLPFEEK_03368 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICLPFEEK_03369 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICLPFEEK_03370 4.09e-142 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
ICLPFEEK_03371 1.55e-133 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICLPFEEK_03372 1.52e-189 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
ICLPFEEK_03373 1.19e-232 ccpB - - K - - - Transcriptional regulator
ICLPFEEK_03374 5.93e-89 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICLPFEEK_03375 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
ICLPFEEK_03376 7.58e-213 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
ICLPFEEK_03377 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
ICLPFEEK_03378 0.0 - 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
ICLPFEEK_03380 5.52e-92 ynaF - - - - - - -
ICLPFEEK_03381 1.02e-106 - - - - - - - -
ICLPFEEK_03382 9.78e-38 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
ICLPFEEK_03383 7.43e-130 - - - - - - - -
ICLPFEEK_03384 3.96e-184 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
ICLPFEEK_03385 6.24e-214 - - - K - - - Transcriptional regulator
ICLPFEEK_03386 7.04e-89 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
ICLPFEEK_03387 2.02e-212 - - - M - - - Domain of Unknown Function (DUF1259)
ICLPFEEK_03388 6.58e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
ICLPFEEK_03389 3.2e-100 yybA - - K - - - transcriptional
ICLPFEEK_03390 3.4e-197 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
ICLPFEEK_03391 8.26e-91 - - - K - - - Winged helix DNA-binding domain
ICLPFEEK_03392 1.7e-148 ydgI - - C - - - nitroreductase
ICLPFEEK_03393 9.61e-75 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
ICLPFEEK_03394 9.22e-213 yybE - - K - - - Transcriptional regulator
ICLPFEEK_03395 3.29e-279 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
ICLPFEEK_03396 1.13e-129 - - - E - - - LysE type translocator
ICLPFEEK_03397 4.38e-209 - - - K - - - LysR substrate binding domain
ICLPFEEK_03398 4.47e-22 - - - G - - - Major Facilitator Superfamily
ICLPFEEK_03399 5.5e-209 - - - G - - - Major Facilitator Superfamily
ICLPFEEK_03400 5.75e-119 - - - S - - - PFAM DinB family protein
ICLPFEEK_03401 4.15e-153 - - - K - - - FCD domain
ICLPFEEK_03402 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
ICLPFEEK_03403 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
ICLPFEEK_03404 2.14e-199 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ICLPFEEK_03405 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
ICLPFEEK_03406 4.56e-87 yybR - - K - - - Transcriptional regulator
ICLPFEEK_03407 1.88e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
ICLPFEEK_03409 3.68e-206 yybS - - S - - - membrane
ICLPFEEK_03410 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
ICLPFEEK_03411 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
ICLPFEEK_03412 1.99e-165 - - - KLT - - - COG0515 Serine threonine protein kinase
ICLPFEEK_03413 1.85e-158 - - - S - - - GlcNAc-PI de-N-acetylase
ICLPFEEK_03414 0.0 - - - M - - - Glycosyltransferase Family 4
ICLPFEEK_03415 2.05e-300 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
ICLPFEEK_03416 1.2e-263 - - - S - - - Ecdysteroid kinase
ICLPFEEK_03417 1.55e-315 - - - M - - - Glycosyltransferase Family 4
ICLPFEEK_03418 7.2e-56 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase activity
ICLPFEEK_03419 3.6e-25 yycC - - K - - - YycC-like protein
ICLPFEEK_03421 1.88e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
ICLPFEEK_03422 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
ICLPFEEK_03423 4.87e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICLPFEEK_03424 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICLPFEEK_03429 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_03430 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_03431 0.0 yycH - - S - - - protein conserved in bacteria
ICLPFEEK_03432 1.77e-197 yycI - - S - - - protein conserved in bacteria
ICLPFEEK_03433 9.84e-192 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
ICLPFEEK_03434 4.87e-280 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICLPFEEK_03435 8.72e-15 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_03436 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
ICLPFEEK_03437 2.51e-247 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
ICLPFEEK_03438 0.0 - - - - - - - -
ICLPFEEK_03439 1.3e-252 - - - S - - - Major Facilitator Superfamily
ICLPFEEK_03440 0.0 - - - S - - - ABC transporter
ICLPFEEK_03441 4.53e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
ICLPFEEK_03442 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
ICLPFEEK_03443 6.09e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
ICLPFEEK_03444 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
ICLPFEEK_03445 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
ICLPFEEK_03446 1.47e-265 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
ICLPFEEK_03448 4.31e-115 yycN - - K - - - Acetyltransferase
ICLPFEEK_03449 3.31e-237 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
ICLPFEEK_03450 8.65e-174 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ICLPFEEK_03451 1.65e-286 yycP - - - - - - -
ICLPFEEK_03454 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICLPFEEK_03455 1.91e-241 - - - - - - - -
ICLPFEEK_03456 1.72e-305 - - - T - - - Putative serine esterase (DUF676)
ICLPFEEK_03457 9.72e-11 - - - - - - - -
ICLPFEEK_03458 0.0 - - - L - - - ATPase involved in DNA repair
ICLPFEEK_03460 5.15e-08 - - - L - - - resolvase
ICLPFEEK_03462 3.74e-242 - - - S - - - Fusaric acid resistance protein-like
ICLPFEEK_03463 8.91e-248 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ICLPFEEK_03464 7.31e-126 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
ICLPFEEK_03465 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
ICLPFEEK_03466 9.17e-205 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
ICLPFEEK_03467 4.71e-112 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
ICLPFEEK_03468 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
ICLPFEEK_03469 5.26e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
ICLPFEEK_03470 1.44e-294 - - - S - - - Fic/DOC family
ICLPFEEK_03471 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
ICLPFEEK_03472 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
ICLPFEEK_03473 5.06e-167 - - - E - - - Ring-cleavage extradiol dioxygenase
ICLPFEEK_03474 2.33e-98 yxaI - - S - - - membrane protein domain
ICLPFEEK_03475 1.07e-262 - - - EGP - - - Major Facilitator Superfamily
ICLPFEEK_03476 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
ICLPFEEK_03477 3.04e-86 - - - S - - - Family of unknown function (DUF5391)
ICLPFEEK_03478 8.79e-192 yxaL - - S - - - PQQ-like domain
ICLPFEEK_03479 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
ICLPFEEK_03480 2.61e-282 yxbF - - K - - - Bacterial regulatory proteins, tetR family
ICLPFEEK_03481 3.84e-259 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
ICLPFEEK_03482 3.03e-257 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_03483 7.82e-134 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICLPFEEK_03484 1.51e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
ICLPFEEK_03485 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
ICLPFEEK_03486 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ICLPFEEK_03487 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
ICLPFEEK_03488 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
ICLPFEEK_03489 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ICLPFEEK_03490 6.21e-203 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
ICLPFEEK_03491 2.92e-233 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
ICLPFEEK_03492 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
ICLPFEEK_03493 3.53e-227 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
ICLPFEEK_03494 3.29e-297 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
ICLPFEEK_03495 2.68e-252 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
ICLPFEEK_03496 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
ICLPFEEK_03497 8.8e-203 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
ICLPFEEK_03498 1.46e-206 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
ICLPFEEK_03499 1.89e-170 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
ICLPFEEK_03500 1.36e-167 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
ICLPFEEK_03501 3.2e-212 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_03502 6.65e-178 yvrH - - T - - - Transcriptional regulator
ICLPFEEK_03503 0.0 - - - T - - - Histidine kinase
ICLPFEEK_03504 4.84e-161 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICLPFEEK_03505 6.81e-225 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
ICLPFEEK_03506 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
ICLPFEEK_03507 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
ICLPFEEK_03508 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
ICLPFEEK_03509 9.5e-208 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
ICLPFEEK_03510 6.1e-204 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
ICLPFEEK_03511 1.02e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
ICLPFEEK_03512 4.3e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICLPFEEK_03513 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICLPFEEK_03514 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICLPFEEK_03515 3.42e-68 yqzD - - - - - - -
ICLPFEEK_03516 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
ICLPFEEK_03517 8e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICLPFEEK_03518 5.38e-11 yqgO - - - - - - -
ICLPFEEK_03519 3.9e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
ICLPFEEK_03520 1.23e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
ICLPFEEK_03521 1.3e-286 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
ICLPFEEK_03522 1.32e-256 yqgU - - - - - - -
ICLPFEEK_03523 2.99e-65 dglA - - S - - - Thiamine-binding protein
ICLPFEEK_03524 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
ICLPFEEK_03525 5.96e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
ICLPFEEK_03526 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
ICLPFEEK_03527 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
ICLPFEEK_03529 1.5e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ICLPFEEK_03530 6.5e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
ICLPFEEK_03531 4.53e-239 yqxL - - P - - - Mg2 transporter protein
ICLPFEEK_03532 1.34e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICLPFEEK_03533 2.62e-239 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
ICLPFEEK_03534 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
ICLPFEEK_03535 2.37e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
ICLPFEEK_03536 6.31e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
ICLPFEEK_03537 9.51e-90 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
ICLPFEEK_03538 1.2e-83 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
ICLPFEEK_03539 2e-36 yqzE - - S - - - YqzE-like protein
ICLPFEEK_03540 1.69e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
ICLPFEEK_03541 5.91e-159 yqxM - - - ko:K19433 - ko00000 -
ICLPFEEK_03542 3.27e-103 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
ICLPFEEK_03543 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
ICLPFEEK_03544 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
ICLPFEEK_03545 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
ICLPFEEK_03546 1.11e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
ICLPFEEK_03547 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
ICLPFEEK_03548 2.44e-266 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
ICLPFEEK_03549 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICLPFEEK_03550 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICLPFEEK_03551 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
ICLPFEEK_03552 6.72e-206 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
ICLPFEEK_03553 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
ICLPFEEK_03554 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
ICLPFEEK_03555 7.65e-83 yqhP - - - - - - -
ICLPFEEK_03556 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
ICLPFEEK_03557 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
ICLPFEEK_03558 1.27e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
ICLPFEEK_03559 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICLPFEEK_03560 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
ICLPFEEK_03561 5.39e-222 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
ICLPFEEK_03562 5.93e-113 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
ICLPFEEK_03563 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
ICLPFEEK_03564 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
ICLPFEEK_03565 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
ICLPFEEK_03566 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
ICLPFEEK_03567 3.48e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
ICLPFEEK_03568 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
ICLPFEEK_03569 2.32e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICLPFEEK_03570 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
ICLPFEEK_03571 1.93e-87 yqhY - - S - - - protein conserved in bacteria
ICLPFEEK_03572 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICLPFEEK_03573 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICLPFEEK_03574 6.82e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICLPFEEK_03575 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICLPFEEK_03576 8.13e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
ICLPFEEK_03577 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ICLPFEEK_03578 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
ICLPFEEK_03579 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
ICLPFEEK_03580 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
ICLPFEEK_03581 3.22e-306 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
ICLPFEEK_03582 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
ICLPFEEK_03583 5.23e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICLPFEEK_03586 3.37e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
ICLPFEEK_03588 6.93e-147 - - - K - - - Protein of unknown function (DUF1232)
ICLPFEEK_03589 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
ICLPFEEK_03591 1.69e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
ICLPFEEK_03592 1.9e-175 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
ICLPFEEK_03593 1.38e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
ICLPFEEK_03594 3.72e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
ICLPFEEK_03595 1.93e-264 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
ICLPFEEK_03596 1.85e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
ICLPFEEK_03597 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
ICLPFEEK_03598 6.92e-206 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ICLPFEEK_03599 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
ICLPFEEK_03600 0.0 bkdR - - KT - - - Transcriptional regulator
ICLPFEEK_03601 2.03e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
ICLPFEEK_03602 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
ICLPFEEK_03603 1.2e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
ICLPFEEK_03604 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ICLPFEEK_03605 8.24e-224 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ICLPFEEK_03606 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ICLPFEEK_03607 7.91e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICLPFEEK_03608 1.48e-219 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ICLPFEEK_03609 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
ICLPFEEK_03610 5.83e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
ICLPFEEK_03611 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
ICLPFEEK_03612 2.58e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
ICLPFEEK_03613 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
ICLPFEEK_03614 5.47e-125 yqjB - - S - - - protein conserved in bacteria
ICLPFEEK_03616 9.74e-98 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
ICLPFEEK_03617 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
ICLPFEEK_03618 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
ICLPFEEK_03619 1.01e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICLPFEEK_03620 1.3e-34 yqzJ - - - - - - -
ICLPFEEK_03621 1.16e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICLPFEEK_03622 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ICLPFEEK_03623 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICLPFEEK_03624 1.18e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ICLPFEEK_03625 2.72e-190 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ICLPFEEK_03626 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
ICLPFEEK_03627 5.5e-67 - - - S - - - GlpM protein
ICLPFEEK_03628 1.36e-212 - - - K - - - LysR substrate binding domain
ICLPFEEK_03629 5.26e-123 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
ICLPFEEK_03630 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
ICLPFEEK_03633 0.0 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ICLPFEEK_03634 4.81e-169 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
ICLPFEEK_03635 6.38e-183 pdaB - - G - - - Polysaccharide deacetylase
ICLPFEEK_03636 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
ICLPFEEK_03637 6.81e-103 gerD - - - ko:K06294 - ko00000 -
ICLPFEEK_03638 2.21e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
ICLPFEEK_03639 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
ICLPFEEK_03640 3.22e-103 ybaK - - S - - - Protein of unknown function (DUF2521)
ICLPFEEK_03641 8.36e-113 yizA - - S - - - Damage-inducible protein DinB
ICLPFEEK_03642 7.48e-187 ybaJ - - Q - - - Methyltransferase domain
ICLPFEEK_03643 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
ICLPFEEK_03644 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICLPFEEK_03645 9.1e-184 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ICLPFEEK_03646 1.37e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICLPFEEK_03647 1.26e-192 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICLPFEEK_03648 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICLPFEEK_03649 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
ICLPFEEK_03650 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICLPFEEK_03651 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICLPFEEK_03652 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICLPFEEK_03653 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
ICLPFEEK_03654 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICLPFEEK_03655 1.4e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
ICLPFEEK_03656 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ICLPFEEK_03657 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ICLPFEEK_03658 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
ICLPFEEK_03659 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
ICLPFEEK_03660 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICLPFEEK_03661 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICLPFEEK_03662 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICLPFEEK_03663 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICLPFEEK_03664 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICLPFEEK_03665 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICLPFEEK_03666 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICLPFEEK_03667 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICLPFEEK_03668 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICLPFEEK_03669 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
ICLPFEEK_03670 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICLPFEEK_03671 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICLPFEEK_03672 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICLPFEEK_03673 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICLPFEEK_03674 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICLPFEEK_03675 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ICLPFEEK_03676 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
ICLPFEEK_03677 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICLPFEEK_03678 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
ICLPFEEK_03679 1.78e-243 ybaC - - S - - - Alpha/beta hydrolase family
ICLPFEEK_03680 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICLPFEEK_03681 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICLPFEEK_03682 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ICLPFEEK_03683 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICLPFEEK_03684 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
ICLPFEEK_03685 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICLPFEEK_03686 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICLPFEEK_03687 4.37e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
ICLPFEEK_03688 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ICLPFEEK_03689 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICLPFEEK_03690 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ICLPFEEK_03691 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICLPFEEK_03692 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
ICLPFEEK_03693 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ICLPFEEK_03694 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
ICLPFEEK_03695 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
ICLPFEEK_03696 2.48e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICLPFEEK_03697 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ICLPFEEK_03698 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
ICLPFEEK_03699 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
ICLPFEEK_03700 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICLPFEEK_03701 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
ICLPFEEK_03702 3.02e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
ICLPFEEK_03703 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
ICLPFEEK_03704 7.66e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ICLPFEEK_03705 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICLPFEEK_03706 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
ICLPFEEK_03707 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
ICLPFEEK_03708 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
ICLPFEEK_03709 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
ICLPFEEK_03710 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
ICLPFEEK_03711 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICLPFEEK_03712 6.1e-40 yazB - - K - - - transcriptional
ICLPFEEK_03713 8.2e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICLPFEEK_03714 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICLPFEEK_03715 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ICLPFEEK_03716 1.53e-210 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
ICLPFEEK_03717 1.31e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
ICLPFEEK_03718 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICLPFEEK_03719 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
ICLPFEEK_03720 3.86e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
ICLPFEEK_03721 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICLPFEEK_03722 1.41e-178 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ICLPFEEK_03723 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICLPFEEK_03724 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
ICLPFEEK_03725 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ICLPFEEK_03726 1.4e-237 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
ICLPFEEK_03727 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
ICLPFEEK_03728 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
ICLPFEEK_03731 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
ICLPFEEK_03732 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
ICLPFEEK_03733 1.18e-134 yabQ - - S - - - spore cortex biosynthesis protein
ICLPFEEK_03734 5.47e-66 yabP - - S - - - Sporulation protein YabP
ICLPFEEK_03735 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
ICLPFEEK_03736 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
ICLPFEEK_03737 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICLPFEEK_03738 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
ICLPFEEK_03739 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICLPFEEK_03740 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
ICLPFEEK_03741 6.07e-137 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ICLPFEEK_03742 3.72e-138 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ICLPFEEK_03743 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICLPFEEK_03744 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICLPFEEK_03745 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
ICLPFEEK_03746 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
ICLPFEEK_03747 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
ICLPFEEK_03748 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICLPFEEK_03749 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
ICLPFEEK_03750 5.32e-53 veg - - S - - - protein conserved in bacteria
ICLPFEEK_03751 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
ICLPFEEK_03752 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ICLPFEEK_03753 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ICLPFEEK_03754 2.49e-310 yabE - - T - - - protein conserved in bacteria
ICLPFEEK_03755 2.22e-186 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
ICLPFEEK_03756 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICLPFEEK_03757 2.69e-30 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
ICLPFEEK_03758 4.93e-211 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICLPFEEK_03759 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
ICLPFEEK_03760 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
ICLPFEEK_03761 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
ICLPFEEK_03762 9e-189 yaaT - - S - - - stage 0 sporulation protein
ICLPFEEK_03763 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
ICLPFEEK_03764 1.04e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
ICLPFEEK_03765 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
ICLPFEEK_03766 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICLPFEEK_03767 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
ICLPFEEK_03768 4.58e-249 yaaN - - P - - - Belongs to the TelA family
ICLPFEEK_03769 1.24e-137 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
ICLPFEEK_03770 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
ICLPFEEK_03771 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_03772 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_03773 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
ICLPFEEK_03774 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
ICLPFEEK_03775 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
ICLPFEEK_03776 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICLPFEEK_03777 2.41e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICLPFEEK_03778 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICLPFEEK_03779 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ICLPFEEK_03780 1.05e-130 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
ICLPFEEK_03781 3.03e-279 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
ICLPFEEK_03782 1.41e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
ICLPFEEK_03783 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
ICLPFEEK_03785 4.55e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
ICLPFEEK_03786 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICLPFEEK_03787 4.94e-140 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ICLPFEEK_03788 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ICLPFEEK_03789 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
ICLPFEEK_03790 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
ICLPFEEK_03791 3e-236 yaaC - - S - - - YaaC-like Protein
ICLPFEEK_03792 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_03793 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_03794 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLPFEEK_03795 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)