ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MHGHIHEH_00001 8.79e-13 - - - - - - - -
MHGHIHEH_00002 7.4e-309 - - - - - - - -
MHGHIHEH_00003 0.000822 - - - M - - - Domain of unknown function (DUF5011)
MHGHIHEH_00004 1.23e-193 - 2.4.1.9, 3.4.24.40 GH68 M ko:K01406,ko:K20811 ko00500,ko01503,map00500,map01503 ko00000,ko00001,ko01000,ko01002 domain protein
MHGHIHEH_00006 2.89e-315 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHGHIHEH_00007 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MHGHIHEH_00008 9.22e-153 mocA - - S - - - Oxidoreductase
MHGHIHEH_00011 1.72e-64 - - - - - - - -
MHGHIHEH_00012 1.49e-27 - - - - - - - -
MHGHIHEH_00013 8.05e-88 - - - S - - - Protein of unknown function (DUF1093)
MHGHIHEH_00014 2.23e-50 - - - - - - - -
MHGHIHEH_00015 5.14e-143 - 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MHGHIHEH_00016 1.42e-112 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
MHGHIHEH_00017 7.07e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MHGHIHEH_00018 2.57e-169 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHGHIHEH_00019 5.49e-58 - - - - - - - -
MHGHIHEH_00020 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHGHIHEH_00021 1.59e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHGHIHEH_00022 1.35e-150 - - - J - - - HAD-hyrolase-like
MHGHIHEH_00023 3.28e-313 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MHGHIHEH_00024 7.93e-108 - - - FG - - - adenosine 5'-monophosphoramidase activity
MHGHIHEH_00025 2.41e-201 - - - V - - - ABC transporter
MHGHIHEH_00026 0.0 - - - - - - - -
MHGHIHEH_00027 3.49e-106 - - - C - - - nadph quinone reductase
MHGHIHEH_00028 3.9e-48 XK27_04345 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MHGHIHEH_00029 1.32e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MHGHIHEH_00030 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MHGHIHEH_00031 5.11e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MHGHIHEH_00032 3.1e-216 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHGHIHEH_00033 7.94e-207 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHGHIHEH_00034 3.44e-198 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHGHIHEH_00035 3.98e-29 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MHGHIHEH_00036 1.81e-88 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MHGHIHEH_00038 8.02e-230 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MHGHIHEH_00039 1.03e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHGHIHEH_00040 6.78e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MHGHIHEH_00041 1.38e-84 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHGHIHEH_00042 2.76e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHGHIHEH_00043 2.87e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MHGHIHEH_00044 3.64e-70 - - - - - - - -
MHGHIHEH_00045 2.13e-55 - - - - - - - -
MHGHIHEH_00046 1.48e-219 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MHGHIHEH_00047 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MHGHIHEH_00048 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHGHIHEH_00049 9.19e-249 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHGHIHEH_00050 1.14e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MHGHIHEH_00051 1.4e-191 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHGHIHEH_00052 8.27e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MHGHIHEH_00053 2.32e-79 yitW - - S - - - Iron-sulfur cluster assembly protein
MHGHIHEH_00054 3.71e-183 - - - - - - - -
MHGHIHEH_00055 1.88e-223 - - - - - - - -
MHGHIHEH_00056 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MHGHIHEH_00057 2.64e-243 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHGHIHEH_00058 2.21e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MHGHIHEH_00059 4.56e-216 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MHGHIHEH_00061 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MHGHIHEH_00062 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MHGHIHEH_00063 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MHGHIHEH_00064 3.5e-112 ypmB - - S - - - Protein conserved in bacteria
MHGHIHEH_00065 1.15e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MHGHIHEH_00066 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MHGHIHEH_00067 3.19e-146 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MHGHIHEH_00068 7.61e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHGHIHEH_00069 5.94e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MHGHIHEH_00070 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MHGHIHEH_00071 8.49e-156 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHGHIHEH_00072 6.54e-138 ypsA - - S - - - Belongs to the UPF0398 family
MHGHIHEH_00073 7.09e-88 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHGHIHEH_00075 2.69e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MHGHIHEH_00076 2.2e-223 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHGHIHEH_00077 8.85e-47 - - - - - - - -
MHGHIHEH_00078 1e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MHGHIHEH_00079 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MHGHIHEH_00080 3.31e-207 lysR - - K - - - Transcriptional regulator
MHGHIHEH_00081 8.83e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHGHIHEH_00082 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHGHIHEH_00083 8.72e-52 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MHGHIHEH_00084 0.0 - - - S - - - Mga helix-turn-helix domain
MHGHIHEH_00085 5.47e-63 - - - - - - - -
MHGHIHEH_00086 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHGHIHEH_00087 2.09e-143 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
MHGHIHEH_00088 2.37e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MHGHIHEH_00089 8.5e-61 - - - S - - - Family of unknown function (DUF5322)
MHGHIHEH_00090 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MHGHIHEH_00091 2.41e-106 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHGHIHEH_00092 1.48e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHGHIHEH_00093 1.05e-125 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHGHIHEH_00094 1.64e-299 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MHGHIHEH_00095 7.64e-229 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MHGHIHEH_00096 4.91e-303 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHGHIHEH_00097 5.32e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHGHIHEH_00098 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MHGHIHEH_00099 2.13e-197 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHGHIHEH_00100 4.62e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHGHIHEH_00101 2.06e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHGHIHEH_00102 8.27e-189 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Phosphate acetyl/butaryl transferase
MHGHIHEH_00103 1.51e-259 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Acetokinase family
MHGHIHEH_00104 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
MHGHIHEH_00105 9.14e-239 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MHGHIHEH_00106 3.05e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
MHGHIHEH_00107 3.21e-287 bfmBB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
MHGHIHEH_00108 1.23e-226 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHGHIHEH_00109 1.36e-248 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MHGHIHEH_00110 2.87e-65 - - - S - - - MazG-like family
MHGHIHEH_00111 0.0 FbpA - - K - - - Fibronectin-binding protein
MHGHIHEH_00112 2.95e-205 - - - S - - - EDD domain protein, DegV family
MHGHIHEH_00113 6.76e-129 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MHGHIHEH_00114 6.93e-261 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHGHIHEH_00115 3.15e-277 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHGHIHEH_00116 2.06e-144 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHGHIHEH_00117 4.14e-295 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHGHIHEH_00118 3.22e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MHGHIHEH_00119 5.08e-131 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHGHIHEH_00120 2.66e-158 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHGHIHEH_00121 1.42e-169 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHGHIHEH_00122 1.01e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MHGHIHEH_00123 2.48e-69 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
MHGHIHEH_00124 4.92e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHGHIHEH_00125 4.85e-143 - - - C - - - Nitroreductase family
MHGHIHEH_00126 7.34e-86 - - - K - - - Acetyltransferase (GNAT) domain
MHGHIHEH_00127 3.04e-64 - - - K - - - Acetyltransferase (GNAT) domain
MHGHIHEH_00128 8.74e-240 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MHGHIHEH_00129 8.31e-158 - - - T - - - Transcriptional regulatory protein, C terminal
MHGHIHEH_00130 9.98e-219 kinG - - T - - - Histidine kinase-like ATPases
MHGHIHEH_00131 2.68e-176 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00132 0.0 XK27_05700 - - V ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
MHGHIHEH_00133 7.18e-79 - - - - - - - -
MHGHIHEH_00134 2.86e-267 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
MHGHIHEH_00135 3.24e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MHGHIHEH_00136 2.6e-232 - - - K - - - LysR substrate binding domain
MHGHIHEH_00137 2.56e-217 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHGHIHEH_00138 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MHGHIHEH_00139 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHGHIHEH_00140 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHGHIHEH_00141 6.92e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHGHIHEH_00142 3.11e-218 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MHGHIHEH_00143 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHGHIHEH_00144 2.06e-119 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHGHIHEH_00145 1.66e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MHGHIHEH_00146 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHGHIHEH_00147 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHGHIHEH_00148 2.69e-188 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MHGHIHEH_00149 5.87e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHGHIHEH_00150 1.03e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHGHIHEH_00151 6.29e-180 - - - K - - - Helix-turn-helix domain
MHGHIHEH_00152 6.99e-242 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
MHGHIHEH_00153 8.1e-76 - - - - - - - -
MHGHIHEH_00154 4.27e-10 - - - - - - - -
MHGHIHEH_00155 5.04e-77 - - - S - - - Psort location Cytoplasmic, score
MHGHIHEH_00156 9.79e-48 XK27_02555 - - - - - - -
MHGHIHEH_00157 1.72e-316 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MHGHIHEH_00158 1.03e-54 yozE - - S - - - Belongs to the UPF0346 family
MHGHIHEH_00159 1.75e-110 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHGHIHEH_00160 3.18e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MHGHIHEH_00161 2.41e-196 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MHGHIHEH_00162 4.9e-190 WQ51_01275 - - S - - - EDD domain protein, DegV family
MHGHIHEH_00163 2.61e-148 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MHGHIHEH_00164 1.04e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHGHIHEH_00165 8.15e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHGHIHEH_00166 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00167 2.95e-110 - - - - - - - -
MHGHIHEH_00168 5.31e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHGHIHEH_00169 8.71e-200 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHGHIHEH_00170 1.52e-302 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MHGHIHEH_00171 1.2e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHGHIHEH_00172 7.41e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MHGHIHEH_00173 4.93e-303 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MHGHIHEH_00174 2.04e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MHGHIHEH_00175 1.68e-104 - - - M - - - Lysin motif
MHGHIHEH_00176 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MHGHIHEH_00177 1.19e-230 - - - S - - - Helix-turn-helix domain
MHGHIHEH_00178 1.16e-60 fer - - C ko:K05337 - ko00000 4Fe-4S single cluster domain of Ferredoxin I
MHGHIHEH_00179 1.52e-123 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHGHIHEH_00180 3.15e-175 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHGHIHEH_00181 8.74e-139 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHGHIHEH_00182 2.17e-159 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHGHIHEH_00183 1.59e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHGHIHEH_00184 9.95e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MHGHIHEH_00185 5.96e-207 yitL - - S ko:K00243 - ko00000 S1 domain
MHGHIHEH_00186 4.31e-95 ytwI - - S - - - Protein of unknown function (DUF441)
MHGHIHEH_00187 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MHGHIHEH_00188 2.21e-227 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHGHIHEH_00189 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MHGHIHEH_00190 8.1e-36 - - - S - - - Protein of unknown function (DUF2929)
MHGHIHEH_00191 2.47e-184 - - - - - - - -
MHGHIHEH_00192 0.0 ycjM 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
MHGHIHEH_00193 6.3e-123 - - - K - - - Domain of unknown function (DUF1836)
MHGHIHEH_00194 1.35e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MHGHIHEH_00195 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHGHIHEH_00196 2.47e-65 - - - S - - - Lipopolysaccharide assembly protein A domain
MHGHIHEH_00197 7.43e-183 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
MHGHIHEH_00198 7.76e-233 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHGHIHEH_00199 0.0 oatA - - I - - - Acyltransferase
MHGHIHEH_00200 3.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHGHIHEH_00201 2.78e-170 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MHGHIHEH_00202 2.76e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MHGHIHEH_00203 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MHGHIHEH_00204 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHGHIHEH_00205 1.89e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00206 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00207 3.33e-28 - - - - - - - -
MHGHIHEH_00208 2.28e-63 - - - S - - - mazG nucleotide pyrophosphohydrolase
MHGHIHEH_00209 6.46e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MHGHIHEH_00210 3.98e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHGHIHEH_00211 2.74e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHGHIHEH_00212 0.0 yknV - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MHGHIHEH_00213 1.02e-76 - - - K - - - helix_turn_helix, mercury resistance
MHGHIHEH_00214 3.09e-80 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MHGHIHEH_00215 5.48e-154 - - - K ko:K12410 - ko00000,ko01000 Sir2 family
MHGHIHEH_00216 6.59e-90 - - - M - - - Protein of unknown function (DUF3737)
MHGHIHEH_00217 4.73e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHGHIHEH_00218 1.93e-213 - - - S - - - Tetratricopeptide repeat
MHGHIHEH_00219 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHGHIHEH_00220 1.34e-62 - - - - - - - -
MHGHIHEH_00221 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHGHIHEH_00223 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MHGHIHEH_00224 2.07e-221 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MHGHIHEH_00225 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MHGHIHEH_00226 7.34e-148 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MHGHIHEH_00227 1.82e-233 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MHGHIHEH_00228 1.79e-112 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHGHIHEH_00229 9.93e-130 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MHGHIHEH_00230 9.89e-83 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MHGHIHEH_00231 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHGHIHEH_00232 1.66e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHGHIHEH_00233 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MHGHIHEH_00234 3.56e-189 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MHGHIHEH_00235 6.15e-62 yktA - - S - - - Belongs to the UPF0223 family
MHGHIHEH_00236 4.32e-202 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
MHGHIHEH_00237 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MHGHIHEH_00238 0.0 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHGHIHEH_00239 1.15e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MHGHIHEH_00240 1.42e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MHGHIHEH_00241 5.13e-112 - - - S - - - E1-E2 ATPase
MHGHIHEH_00242 4.82e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHGHIHEH_00243 7.04e-63 - - - - - - - -
MHGHIHEH_00244 1.11e-95 - - - - - - - -
MHGHIHEH_00245 2.02e-43 ykzG - - S - - - Belongs to the UPF0356 family
MHGHIHEH_00246 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHGHIHEH_00247 1.15e-232 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MHGHIHEH_00248 1.65e-311 - - - S - - - Sterol carrier protein domain
MHGHIHEH_00249 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHGHIHEH_00250 3.26e-151 - - - S - - - repeat protein
MHGHIHEH_00251 4.69e-159 pgm6 - - G - - - phosphoglycerate mutase
MHGHIHEH_00252 4.09e-304 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHGHIHEH_00253 0.0 uvrA2 - - L - - - ABC transporter
MHGHIHEH_00254 1.21e-75 XK27_04120 - - S - - - Putative amino acid metabolism
MHGHIHEH_00255 3.99e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MHGHIHEH_00256 1.95e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHGHIHEH_00257 2.86e-39 - - - - - - - -
MHGHIHEH_00258 6.12e-123 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MHGHIHEH_00259 8.03e-151 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHGHIHEH_00260 7.29e-270 yaaN - - P - - - Toxic anion resistance protein (TelA)
MHGHIHEH_00261 0.0 ydiC1 - - EGP - - - Major Facilitator
MHGHIHEH_00262 5.93e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHGHIHEH_00263 4.62e-48 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MHGHIHEH_00264 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHGHIHEH_00265 8.49e-120 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA protein
MHGHIHEH_00266 1.45e-186 ylmH - - S - - - S4 domain protein
MHGHIHEH_00267 5.58e-60 ylmG - - S ko:K02221 - ko00000,ko02044 integral membrane protein
MHGHIHEH_00268 5.95e-101 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHGHIHEH_00269 6.55e-291 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHGHIHEH_00270 1.44e-311 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHGHIHEH_00271 5.91e-200 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHGHIHEH_00272 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHGHIHEH_00273 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHGHIHEH_00274 1.09e-229 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHGHIHEH_00275 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHGHIHEH_00276 1.6e-68 ftsL - - D - - - cell division protein FtsL
MHGHIHEH_00277 6.77e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHGHIHEH_00278 1.61e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MHGHIHEH_00279 7.11e-60 - - - - - - - -
MHGHIHEH_00280 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHGHIHEH_00281 2.32e-193 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MHGHIHEH_00282 3.29e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MHGHIHEH_00283 4.79e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00284 8.63e-182 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MHGHIHEH_00285 2.69e-148 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHGHIHEH_00286 8.66e-113 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MHGHIHEH_00287 1.88e-191 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MHGHIHEH_00288 4.82e-229 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MHGHIHEH_00289 1.97e-152 radC - - L ko:K03630 - ko00000 DNA repair protein
MHGHIHEH_00290 8.07e-148 - - - S - - - Haloacid dehalogenase-like hydrolase
MHGHIHEH_00291 5.15e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MHGHIHEH_00292 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHGHIHEH_00293 1.24e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHGHIHEH_00294 1.42e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHGHIHEH_00295 3.53e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MHGHIHEH_00296 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHGHIHEH_00297 7.1e-111 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MHGHIHEH_00298 5.31e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHGHIHEH_00301 7e-123 - - - - - - - -
MHGHIHEH_00302 1.19e-189 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
MHGHIHEH_00303 6.77e-71 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
MHGHIHEH_00304 2.35e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHGHIHEH_00305 1.7e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHGHIHEH_00306 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MHGHIHEH_00307 8.85e-76 - - - - - - - -
MHGHIHEH_00308 4.83e-108 - - - S - - - ASCH
MHGHIHEH_00309 1.32e-33 - - - - - - - -
MHGHIHEH_00310 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHGHIHEH_00311 8.58e-64 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
MHGHIHEH_00312 1.43e-176 - - - V - - - ABC transporter transmembrane region
MHGHIHEH_00313 2.22e-259 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHGHIHEH_00314 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MHGHIHEH_00315 3.18e-127 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHGHIHEH_00316 1.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHGHIHEH_00317 7.24e-287 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MHGHIHEH_00318 1.74e-222 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MHGHIHEH_00319 1.64e-212 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHGHIHEH_00320 3.07e-181 terC - - P - - - Integral membrane protein TerC family
MHGHIHEH_00321 1.27e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHGHIHEH_00322 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHGHIHEH_00323 1.29e-60 ylxQ - - J - - - ribosomal protein
MHGHIHEH_00324 9.63e-61 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MHGHIHEH_00325 1.68e-276 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MHGHIHEH_00326 1.33e-110 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MHGHIHEH_00327 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHGHIHEH_00328 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHGHIHEH_00329 3.52e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MHGHIHEH_00330 7.66e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MHGHIHEH_00331 4.31e-179 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHGHIHEH_00332 4.96e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHGHIHEH_00333 5.86e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MHGHIHEH_00334 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHGHIHEH_00335 1.18e-182 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MHGHIHEH_00336 5.38e-61 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MHGHIHEH_00337 2.39e-167 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MHGHIHEH_00338 8.45e-160 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MHGHIHEH_00339 1.85e-290 yhdG - - E ko:K03294 - ko00000 Amino Acid
MHGHIHEH_00340 4.28e-181 yejC - - S - - - Protein of unknown function (DUF1003)
MHGHIHEH_00341 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_00342 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_00343 1.39e-40 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MHGHIHEH_00344 2.84e-48 ynzC - - S - - - UPF0291 protein
MHGHIHEH_00345 3.28e-28 - - - - - - - -
MHGHIHEH_00346 2e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHGHIHEH_00347 1.76e-185 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MHGHIHEH_00348 2.16e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHGHIHEH_00349 1.55e-51 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MHGHIHEH_00350 2.97e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MHGHIHEH_00351 2.16e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHGHIHEH_00352 1.26e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHGHIHEH_00353 7.91e-70 - - - - - - - -
MHGHIHEH_00354 4.3e-231 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHGHIHEH_00355 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MHGHIHEH_00356 2.8e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHGHIHEH_00357 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHGHIHEH_00358 1.16e-193 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHGHIHEH_00359 3.2e-216 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00360 1.62e-228 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHGHIHEH_00361 4.24e-247 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHGHIHEH_00362 3.21e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHGHIHEH_00363 5.5e-239 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHGHIHEH_00364 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHGHIHEH_00365 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MHGHIHEH_00366 5.83e-75 yloU - - S - - - Asp23 family, cell envelope-related function
MHGHIHEH_00367 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MHGHIHEH_00368 2.62e-166 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MHGHIHEH_00369 4.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MHGHIHEH_00370 5.6e-221 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHGHIHEH_00371 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHGHIHEH_00372 5.22e-174 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MHGHIHEH_00373 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHGHIHEH_00374 1.96e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHGHIHEH_00375 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHGHIHEH_00376 8e-275 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHGHIHEH_00377 1.77e-47 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHGHIHEH_00378 2.52e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MHGHIHEH_00379 1.65e-117 - - - S ko:K07001 - ko00000 Patatin-like phospholipase
MHGHIHEH_00380 2.71e-66 - - - - - - - -
MHGHIHEH_00381 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MHGHIHEH_00382 4.19e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHGHIHEH_00383 8.09e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MHGHIHEH_00384 9.01e-190 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHGHIHEH_00385 1.42e-43 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHGHIHEH_00386 1.56e-295 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHGHIHEH_00387 4.46e-193 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHGHIHEH_00388 6.72e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHGHIHEH_00389 9.44e-99 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MHGHIHEH_00390 6.06e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHGHIHEH_00392 7.17e-258 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHGHIHEH_00393 1.6e-63 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MHGHIHEH_00394 1.77e-74 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MHGHIHEH_00395 5.83e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MHGHIHEH_00396 1.17e-16 - - - - - - - -
MHGHIHEH_00397 2.12e-40 - - - - - - - -
MHGHIHEH_00399 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MHGHIHEH_00400 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MHGHIHEH_00401 1.32e-80 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MHGHIHEH_00402 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MHGHIHEH_00403 5.52e-303 ynbB - - P - - - aluminum resistance
MHGHIHEH_00404 4.43e-222 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHGHIHEH_00405 3.33e-35 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MHGHIHEH_00406 1.93e-96 yqhL - - P - - - Rhodanese-like protein
MHGHIHEH_00407 9.32e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MHGHIHEH_00408 6.79e-55 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MHGHIHEH_00409 1.33e-157 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MHGHIHEH_00410 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHGHIHEH_00411 0.0 - - - S - - - Bacterial membrane protein YfhO
MHGHIHEH_00412 1.15e-71 yneR - - S - - - Belongs to the HesB IscA family
MHGHIHEH_00413 2.04e-149 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MHGHIHEH_00414 6.31e-230 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHGHIHEH_00415 3.14e-164 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MHGHIHEH_00416 1.05e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHGHIHEH_00417 3.43e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MHGHIHEH_00418 7.4e-265 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHGHIHEH_00419 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHGHIHEH_00420 1.02e-258 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHGHIHEH_00421 1.2e-87 yodB - - K - - - Transcriptional regulator, HxlR family
MHGHIHEH_00422 3.09e-122 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHGHIHEH_00423 4.47e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHGHIHEH_00424 4.17e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MHGHIHEH_00425 8.99e-229 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHGHIHEH_00426 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHGHIHEH_00427 1.01e-157 csrR - - K - - - response regulator
MHGHIHEH_00428 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHGHIHEH_00429 3.14e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MHGHIHEH_00430 2.27e-268 ylbM - - S - - - Belongs to the UPF0348 family
MHGHIHEH_00431 8.06e-177 yccK - - Q - - - ubiE/COQ5 methyltransferase family
MHGHIHEH_00432 1.18e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHGHIHEH_00433 3.21e-142 yqeK - - H - - - Hydrolase, HD family
MHGHIHEH_00434 2.72e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHGHIHEH_00435 3.95e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MHGHIHEH_00436 3.02e-262 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MHGHIHEH_00437 6.63e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MHGHIHEH_00438 2.77e-220 ykcA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHGHIHEH_00439 2.74e-243 mhqA_2 - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHGHIHEH_00440 4.31e-157 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
MHGHIHEH_00441 7.15e-230 - - - C - - - Alcohol dehydrogenase GroES-like domain
MHGHIHEH_00442 8.27e-130 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MHGHIHEH_00443 1.02e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHGHIHEH_00444 1.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MHGHIHEH_00445 7.46e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHGHIHEH_00446 9.8e-167 - - - S - - - SseB protein N-terminal domain
MHGHIHEH_00447 5.3e-70 - - - - - - - -
MHGHIHEH_00448 1.17e-130 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
MHGHIHEH_00449 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHGHIHEH_00451 1.02e-180 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MHGHIHEH_00452 1.04e-303 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MHGHIHEH_00453 2.06e-103 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHGHIHEH_00454 7.76e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHGHIHEH_00455 2.52e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHGHIHEH_00456 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHGHIHEH_00457 2.55e-155 ybhL - - S ko:K06890 - ko00000 Inhibitor of apoptosis-promoting Bax1
MHGHIHEH_00458 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MHGHIHEH_00459 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHGHIHEH_00460 3.17e-149 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHGHIHEH_00461 5.32e-73 ytpP - - CO - - - Thioredoxin
MHGHIHEH_00462 3.03e-06 - - - S - - - Small secreted protein
MHGHIHEH_00463 1.35e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHGHIHEH_00464 4.51e-189 ytmP - - M - - - Choline/ethanolamine kinase
MHGHIHEH_00465 1.01e-275 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_00466 2.4e-172 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00467 1.67e-99 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MHGHIHEH_00468 5.77e-81 - - - S - - - YtxH-like protein
MHGHIHEH_00469 5.26e-205 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHGHIHEH_00470 8.42e-232 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHGHIHEH_00471 1.03e-72 - - - S - - - Control of competence regulator ComK, YlbF/YmcA
MHGHIHEH_00472 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHGHIHEH_00473 1.3e-198 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MHGHIHEH_00474 3.31e-98 argR1 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHGHIHEH_00475 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MHGHIHEH_00477 1.97e-88 - - - - - - - -
MHGHIHEH_00478 1.16e-31 - - - - - - - -
MHGHIHEH_00479 3.67e-227 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
MHGHIHEH_00480 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MHGHIHEH_00481 1.44e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MHGHIHEH_00482 1.13e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHGHIHEH_00483 3.28e-176 yhfI - - S - - - Metallo-beta-lactamase superfamily
MHGHIHEH_00484 7.88e-121 traP 1.14.99.57, 6.2.1.3 - S ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 heme oxygenase (decyclizing) activity
MHGHIHEH_00485 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MHGHIHEH_00486 1.14e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_00487 1.57e-159 rrp1 - - K ko:K02483 - ko00000,ko02022 response regulator
MHGHIHEH_00488 4.52e-262 - - - T ko:K19168 - ko00000,ko02048 His Kinase A (phosphoacceptor) domain
MHGHIHEH_00489 3.11e-141 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHGHIHEH_00490 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
MHGHIHEH_00491 1.17e-100 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MHGHIHEH_00492 3.66e-156 malR - - KT ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
MHGHIHEH_00493 0.0 dpiB 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
MHGHIHEH_00494 1.54e-291 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 2-hydroxycarboxylate transporter family
MHGHIHEH_00495 2.11e-271 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
MHGHIHEH_00496 5.19e-62 yjdF3 - - S - - - Protein of unknown function (DUF2992)
MHGHIHEH_00497 2.03e-147 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MHGHIHEH_00498 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MHGHIHEH_00499 1.06e-186 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MHGHIHEH_00500 1.34e-126 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHGHIHEH_00501 4.08e-271 - - - M - - - Glycosyl transferases group 1
MHGHIHEH_00502 0.0 yebA - - E - - - Transglutaminase/protease-like homologues
MHGHIHEH_00503 1.76e-234 - - - S - - - Protein of unknown function DUF58
MHGHIHEH_00504 6.08e-181 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
MHGHIHEH_00505 7.75e-138 - - - S ko:K06384 - ko00000 Stage II sporulation protein M
MHGHIHEH_00506 9.37e-129 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHGHIHEH_00507 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_00508 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_00509 1.09e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00510 7.92e-215 - - - G - - - Phosphotransferase enzyme family
MHGHIHEH_00511 1.1e-185 - - - S - - - AAA ATPase domain
MHGHIHEH_00512 0.0 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
MHGHIHEH_00513 8.68e-106 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MHGHIHEH_00514 8.12e-69 - - - - - - - -
MHGHIHEH_00515 5.96e-53 - - - S - - - Iron-sulphur cluster biosynthesis
MHGHIHEH_00516 1.33e-166 - - - S - - - Protein of unknown function (DUF975)
MHGHIHEH_00517 2.01e-303 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHGHIHEH_00518 4.51e-41 - - - - - - - -
MHGHIHEH_00519 3.81e-172 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00520 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00522 6.17e-204 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
MHGHIHEH_00523 8.33e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
MHGHIHEH_00524 1.03e-242 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
MHGHIHEH_00526 1.97e-278 - - - EGP - - - Major facilitator Superfamily
MHGHIHEH_00527 1.38e-228 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00528 1.57e-171 manM - - G ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MHGHIHEH_00529 1.73e-216 manN - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MHGHIHEH_00530 1.08e-84 manO - - S - - - Domain of unknown function (DUF956)
MHGHIHEH_00531 2.11e-220 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MHGHIHEH_00532 1.32e-272 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
MHGHIHEH_00533 0.0 - - - EGP - - - Major Facilitator Superfamily
MHGHIHEH_00534 1.11e-146 ycaC - - Q - - - Isochorismatase family
MHGHIHEH_00535 8.74e-116 - - - S - - - AAA domain
MHGHIHEH_00536 7.49e-110 - - - F - - - NUDIX domain
MHGHIHEH_00537 1.06e-139 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MHGHIHEH_00538 3.41e-71 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MHGHIHEH_00539 5.86e-68 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00540 1.97e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
MHGHIHEH_00541 1.76e-298 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGHIHEH_00542 9.09e-97 - - - S - - - Domain of unknown function (DUF3284)
MHGHIHEH_00543 3.77e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MHGHIHEH_00544 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MHGHIHEH_00545 1.34e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHGHIHEH_00546 0.0 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00547 3.54e-156 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha/beta hydrolase family
MHGHIHEH_00548 3.03e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHGHIHEH_00549 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHGHIHEH_00550 0.0 yycH - - S - - - YycH protein
MHGHIHEH_00551 1.05e-182 yycI - - S - - - YycH protein
MHGHIHEH_00552 4.32e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MHGHIHEH_00553 1.7e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MHGHIHEH_00554 2.35e-92 - - - S - - - Iron-sulphur cluster biosynthesis
MHGHIHEH_00555 1.8e-99 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHGHIHEH_00556 0.0 cadA - - P - - - P-type ATPase
MHGHIHEH_00557 4.2e-134 - - - - - - - -
MHGHIHEH_00558 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHGHIHEH_00559 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MHGHIHEH_00560 3.05e-91 - - - - - - - -
MHGHIHEH_00561 6.32e-253 ysdE - - P - - - Citrate transporter
MHGHIHEH_00562 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHGHIHEH_00563 3.43e-101 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHGHIHEH_00564 1.35e-99 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHGHIHEH_00565 1.87e-57 - - - - - - - -
MHGHIHEH_00566 3.06e-157 - - - GM - - - Male sterility protein
MHGHIHEH_00567 1.6e-55 - - - K - - - helix_turn_helix, mercury resistance
MHGHIHEH_00568 7.95e-103 - - - K - - - Acetyltransferase (GNAT) domain
MHGHIHEH_00569 1.33e-178 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MHGHIHEH_00570 1.19e-235 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MHGHIHEH_00571 5.71e-121 - - - E - - - HAD-hyrolase-like
MHGHIHEH_00572 3.35e-121 yfbM - - K - - - FR47-like protein
MHGHIHEH_00573 2.48e-170 - - - S - - - -acetyltransferase
MHGHIHEH_00574 2.16e-68 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
MHGHIHEH_00575 9.2e-146 - - - Q - - - Methyltransferase
MHGHIHEH_00576 1.26e-217 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MHGHIHEH_00577 7.17e-258 - - - S - - - endonuclease exonuclease phosphatase family protein
MHGHIHEH_00578 2.51e-176 XK27_08455 - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00579 1.56e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_00580 1.67e-105 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00581 3.72e-210 - - - K - - - Helix-turn-helix domain, rpiR family
MHGHIHEH_00582 4.79e-196 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHGHIHEH_00583 2.19e-249 - - - V - - - Beta-lactamase
MHGHIHEH_00584 1.12e-245 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MHGHIHEH_00585 1.39e-185 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MHGHIHEH_00586 1.1e-173 - - - F - - - NUDIX domain
MHGHIHEH_00587 1.89e-139 pncA - - Q - - - Isochorismatase family
MHGHIHEH_00588 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHGHIHEH_00589 7.33e-271 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
MHGHIHEH_00590 1.3e-210 - - - P ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type sugar transport systems, permease components
MHGHIHEH_00591 2.92e-192 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00592 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHGHIHEH_00593 1.12e-90 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHGHIHEH_00594 1.09e-154 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MHGHIHEH_00595 1.73e-121 - - - K - - - Helix-turn-helix domain
MHGHIHEH_00597 9.39e-74 ps105 - - - - - - -
MHGHIHEH_00598 7.48e-47 - - - - - - - -
MHGHIHEH_00599 4.94e-119 yveA - - Q - - - Isochorismatase family
MHGHIHEH_00600 1.03e-111 - - - K - - - Acetyltransferase (GNAT) domain
MHGHIHEH_00601 0.0 chaT1 - - U ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MHGHIHEH_00602 6.18e-132 laaE - - K - - - Transcriptional regulator PadR-like family
MHGHIHEH_00603 5.57e-115 - - - M ko:K03828 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHGHIHEH_00604 1.97e-173 farR - - K - - - Helix-turn-helix domain
MHGHIHEH_00605 2.63e-206 - - - G - - - Fructose-bisphosphate aldolase class-II
MHGHIHEH_00606 1.87e-102 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00607 9.89e-64 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00608 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHGHIHEH_00609 0.0 - - - G - - - FGGY family of carbohydrate kinases, C-terminal domain
MHGHIHEH_00610 4.53e-203 - - - G - - - Fructose-bisphosphate aldolase class-II
MHGHIHEH_00611 0.0 - - - K ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00612 1.03e-92 ahaA 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00613 1.33e-105 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00614 3.52e-176 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00615 1.29e-197 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_00616 8.07e-260 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MHGHIHEH_00617 0.0 - 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
MHGHIHEH_00618 1.07e-93 - - - S - - - Domain of unknown function (DUF4428)
MHGHIHEH_00619 1.7e-264 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
MHGHIHEH_00620 1.37e-271 - - - EGP - - - Transporter, major facilitator family protein
MHGHIHEH_00621 0.0 - 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
MHGHIHEH_00622 3.03e-169 - - - K ko:K03710 - ko00000,ko03000 UTRA
MHGHIHEH_00623 0.0 - - - E - - - Peptidase family M20/M25/M40
MHGHIHEH_00624 6.65e-234 asnA2 3.5.1.1 - E ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MHGHIHEH_00625 5.08e-207 - - - GK - - - ROK family
MHGHIHEH_00626 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MHGHIHEH_00627 1.67e-173 - - - K - - - DeoR C terminal sensor domain
MHGHIHEH_00628 5.08e-262 - 1.1.1.405 - E ko:K05352 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MHGHIHEH_00629 5.03e-95 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00630 2.79e-107 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00631 1.95e-172 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00632 1.29e-201 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_00633 1.15e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MHGHIHEH_00634 4.95e-117 - - - G - - - DeoC/LacD family aldolase
MHGHIHEH_00635 2.47e-251 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MHGHIHEH_00636 4.14e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHGHIHEH_00637 4.59e-275 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
MHGHIHEH_00638 4.89e-105 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00639 0.0 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHGHIHEH_00640 3.36e-61 sgaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00641 5.26e-148 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
MHGHIHEH_00642 8.64e-178 - - - K - - - DeoR C terminal sensor domain
MHGHIHEH_00643 6.24e-212 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
MHGHIHEH_00644 1.45e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHGHIHEH_00645 6.39e-177 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MHGHIHEH_00646 1.23e-162 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_00647 3.16e-110 rbsR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHGHIHEH_00648 1.57e-235 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHGHIHEH_00649 2.48e-268 - - - C - - - Psort location Cytoplasmic, score 8.87
MHGHIHEH_00650 2.29e-39 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHGHIHEH_00651 4.13e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MHGHIHEH_00652 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MHGHIHEH_00653 7.54e-115 srlM1 - - K - - - Glucitol operon activator protein (GutM)
MHGHIHEH_00654 5.81e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MHGHIHEH_00655 8.43e-261 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MHGHIHEH_00656 2.24e-84 - 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHGHIHEH_00657 8.74e-161 - - - H - - - Pfam:Transaldolase
MHGHIHEH_00658 0.0 - - - K - - - Mga helix-turn-helix domain
MHGHIHEH_00659 7.4e-74 - - - S - - - PRD domain
MHGHIHEH_00660 8.65e-81 - - - S - - - Glycine-rich SFCGS
MHGHIHEH_00661 1.1e-76 - - - S - - - Domain of unknown function (DUF4312)
MHGHIHEH_00662 4.79e-176 - - - S - - - Domain of unknown function (DUF4311)
MHGHIHEH_00663 3.79e-155 - - - S - - - Domain of unknown function (DUF4310)
MHGHIHEH_00664 2.47e-274 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
MHGHIHEH_00665 1.51e-260 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
MHGHIHEH_00666 4.63e-176 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
MHGHIHEH_00667 1.33e-255 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00668 1.08e-104 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MHGHIHEH_00669 1.46e-122 - 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
MHGHIHEH_00670 1.77e-256 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHGHIHEH_00671 8.29e-44 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00672 8.2e-63 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00673 1.75e-84 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 SIS domain
MHGHIHEH_00674 1.52e-71 - - - T ko:K02667 ko02020,map02020 ko00000,ko00001,ko00002,ko02022,ko02035 phosphorelay signal transduction system
MHGHIHEH_00675 7.77e-132 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MHGHIHEH_00676 1.49e-108 - 2.7.1.219, 2.7.1.220 - S ko:K22129 - ko00000,ko01000 Putative nucleotide-binding of sugar-metabolising enzyme
MHGHIHEH_00677 1.96e-155 pdxA 1.1.1.408, 1.1.1.409 - H ko:K22024 - ko00000,ko01000 Belongs to the PdxA family
MHGHIHEH_00678 6.59e-256 - - - S - - - DUF218 domain
MHGHIHEH_00679 9.87e-99 - - - K ko:K02538 - ko00000,ko03000 PRD domain
MHGHIHEH_00681 3.77e-33 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHGHIHEH_00682 1.05e-203 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHGHIHEH_00683 6.66e-41 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, galactitol-specific IIB component
MHGHIHEH_00684 1.24e-122 gatY 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHGHIHEH_00685 4.52e-97 - 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Triose-phosphate isomerase
MHGHIHEH_00686 1.61e-85 - - - S - - - Uncharacterised protein family UPF0047
MHGHIHEH_00689 7.58e-134 tnpR1 - - L - - - Resolvase, N terminal domain
MHGHIHEH_00690 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MHGHIHEH_00691 2.64e-208 - - - S - - - reductase
MHGHIHEH_00692 1.68e-98 - - - K - - - helix_turn_helix, mercury resistance
MHGHIHEH_00693 0.0 - - - E - - - Amino acid permease
MHGHIHEH_00694 1.98e-281 - - - S ko:K07045 - ko00000 Amidohydrolase
MHGHIHEH_00695 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase, catalytic domain
MHGHIHEH_00696 3.85e-182 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MHGHIHEH_00697 3.17e-185 - - - H - - - Protein of unknown function (DUF1698)
MHGHIHEH_00698 3.81e-191 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MHGHIHEH_00699 5.8e-248 pbpE - - V - - - Beta-lactamase
MHGHIHEH_00700 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHGHIHEH_00701 3.1e-214 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MHGHIHEH_00702 2.28e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MHGHIHEH_00703 4.89e-139 ydfF - - K - - - Transcriptional
MHGHIHEH_00704 4.97e-255 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
MHGHIHEH_00705 4.23e-64 yczG - - K - - - Helix-turn-helix domain
MHGHIHEH_00706 0.0 - - - L - - - Exonuclease
MHGHIHEH_00707 1.01e-99 - - - O - - - OsmC-like protein
MHGHIHEH_00708 1.03e-242 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MHGHIHEH_00709 4.95e-134 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MHGHIHEH_00710 2.1e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00711 4.1e-130 - - - K - - - Bacterial regulatory proteins, tetR family
MHGHIHEH_00712 7.24e-23 - - - - - - - -
MHGHIHEH_00713 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MHGHIHEH_00714 1.42e-104 - - - - - - - -
MHGHIHEH_00715 5.6e-251 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MHGHIHEH_00716 3.7e-199 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHGHIHEH_00717 0.0 pip - - V ko:K01421 - ko00000 domain protein
MHGHIHEH_00719 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHGHIHEH_00720 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHGHIHEH_00721 5.07e-89 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00722 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MHGHIHEH_00723 7.9e-196 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_00724 2.18e-177 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00725 6.03e-109 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00726 2.33e-237 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MHGHIHEH_00727 1.49e-58 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
MHGHIHEH_00728 7.51e-194 - - - S - - - hydrolase
MHGHIHEH_00729 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MHGHIHEH_00730 8.27e-153 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00731 5.69e-238 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00732 5.12e-112 - - - K - - - Bacterial regulatory proteins, tetR family
MHGHIHEH_00733 1.25e-148 - - - C - - - Flavodoxin
MHGHIHEH_00734 1.68e-170 ypiA - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGHIHEH_00735 2.34e-184 - - - M - - - hydrolase, family 25
MHGHIHEH_00736 1.33e-17 - - - S - - - YvrJ protein family
MHGHIHEH_00738 9.19e-304 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
MHGHIHEH_00739 2.71e-70 - - - C - - - nitroreductase
MHGHIHEH_00741 5.4e-191 - 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 Mannitol dehydrogenase C-terminal domain
MHGHIHEH_00742 6.38e-301 - 2.7.1.197 - G ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00743 1.3e-145 - 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MHGHIHEH_00744 1.64e-78 - - - K - - - DeoR C terminal sensor domain
MHGHIHEH_00745 2.35e-125 - 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MHGHIHEH_00746 2.05e-146 - 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
MHGHIHEH_00747 1.37e-172 - - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MHGHIHEH_00748 1.24e-154 - - - S - - - Haloacid dehalogenase-like hydrolase
MHGHIHEH_00750 0.0 - 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
MHGHIHEH_00751 9.35e-74 - - - - - - - -
MHGHIHEH_00752 2.15e-199 levD - - G ko:K02771 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_00753 6.62e-197 levC - - M ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00754 2.66e-117 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00755 1.17e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00756 0.0 - - - K - - - Sigma-54 interaction domain
MHGHIHEH_00757 3.98e-26 - - - K - - - helix_turn_helix, arabinose operon control protein
MHGHIHEH_00758 4.65e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MHGHIHEH_00759 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00760 1.05e-127 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MHGHIHEH_00761 2.16e-203 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
MHGHIHEH_00762 1.39e-202 - - - K - - - Transcriptional regulator, LysR family
MHGHIHEH_00763 3.33e-303 - - - C - - - FAD dependent oxidoreductase
MHGHIHEH_00764 0.0 sdcS - - P ko:K14445 - ko00000,ko02000 transporter
MHGHIHEH_00765 3.89e-210 kbaY 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHGHIHEH_00766 5.03e-194 manZ - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MHGHIHEH_00767 3.93e-184 - - - U ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00768 4.08e-112 - 2.7.1.206 - G ko:K02813 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00769 2.06e-88 - 2.7.1.206 - G ko:K02812 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00770 5.02e-186 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MHGHIHEH_00771 2.56e-221 - - - K - - - sugar-binding domain protein
MHGHIHEH_00772 4.08e-311 - - - E ko:K19956 ko00051,map00051 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
MHGHIHEH_00773 5.41e-171 - - - K ko:K03710 - ko00000,ko03000 UTRA
MHGHIHEH_00774 5.82e-130 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 sugar phosphate isomerase involved in capsule formation
MHGHIHEH_00775 5.39e-152 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
MHGHIHEH_00776 1.45e-236 - 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MHGHIHEH_00777 1.05e-146 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 - S ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak2
MHGHIHEH_00778 1.83e-279 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MHGHIHEH_00779 5.44e-198 - - - G ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MHGHIHEH_00780 5.6e-170 - - - G ko:K17466 ko00030,ko01120,ko02060,map00030,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00781 5.98e-111 - 2.7.1.203 - G ko:K17465 ko00030,ko01120,ko02060,map00030,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00782 5.33e-98 - 2.7.1.191, 2.7.1.203 - G ko:K02793,ko:K17464 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00783 1.5e-187 - 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MHGHIHEH_00784 0.0 - 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_00785 4.92e-203 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHGHIHEH_00786 0.0 - - - K - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00787 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00788 7.73e-291 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
MHGHIHEH_00789 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00790 2.86e-97 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00791 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
MHGHIHEH_00792 1.35e-171 - 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Pfam:DUF1498
MHGHIHEH_00793 2.14e-232 - - - G - - - Domain of unknown function (DUF4432)
MHGHIHEH_00794 1.42e-219 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
MHGHIHEH_00795 1.08e-63 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00796 5.02e-105 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00797 7.37e-223 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHGHIHEH_00798 1.05e-101 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
MHGHIHEH_00799 0.0 - - - K ko:K02538 - ko00000,ko03000 PRD domain
MHGHIHEH_00800 3.69e-301 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
MHGHIHEH_00801 0.0 - - - K ko:K19505 - ko00000,ko03000 Sigma-54 interaction domain
MHGHIHEH_00802 2.3e-56 - - - K ko:K19505 - ko00000,ko03000 Sigma-54 interaction domain
MHGHIHEH_00803 8.5e-91 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00804 1.12e-116 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00805 2.28e-172 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00806 1.23e-193 - - - G ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MHGHIHEH_00807 1.72e-202 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
MHGHIHEH_00808 3.72e-235 ydeM3 - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
MHGHIHEH_00809 1.72e-169 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
MHGHIHEH_00810 1.01e-213 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
MHGHIHEH_00811 1.56e-282 - - - P - - - Type I phosphodiesterase / nucleotide pyrophosphatase
MHGHIHEH_00812 3.5e-166 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_00813 1.22e-181 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00814 1.23e-228 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHGHIHEH_00815 3.67e-109 - - - - - - - -
MHGHIHEH_00816 2.79e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase
MHGHIHEH_00817 5.11e-93 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
MHGHIHEH_00818 2.37e-91 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MHGHIHEH_00819 2.53e-51 - - - L ko:K07485 - ko00000 Transposase
MHGHIHEH_00822 1.91e-191 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
MHGHIHEH_00823 1.96e-227 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
MHGHIHEH_00824 9.64e-191 - - - S - - - Sulfite exporter TauE/SafE
MHGHIHEH_00825 3.2e-203 - - - K - - - Sugar-specific transcriptional regulator TrmB
MHGHIHEH_00826 7.78e-150 - - - S - - - Zeta toxin
MHGHIHEH_00827 6.47e-208 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHGHIHEH_00828 5.04e-90 - - - - - - - -
MHGHIHEH_00829 1.82e-283 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHGHIHEH_00830 3.38e-66 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00831 4.69e-250 - - - GKT - - - transcriptional antiterminator
MHGHIHEH_00832 0.0 frdC 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
MHGHIHEH_00833 3.9e-172 - - - - - - - -
MHGHIHEH_00834 8.53e-139 - - - - - - - -
MHGHIHEH_00835 3.93e-162 - - - - - - - -
MHGHIHEH_00836 8.83e-114 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHGHIHEH_00837 2.1e-121 - - - - - - - -
MHGHIHEH_00838 7.42e-89 - - - S - - - Protein of unknown function (DUF1093)
MHGHIHEH_00839 1.06e-82 - - - - - - - -
MHGHIHEH_00840 1.12e-82 - - - - - - - -
MHGHIHEH_00841 4.22e-41 - - - - - - - -
MHGHIHEH_00842 1.75e-129 - - - - - - - -
MHGHIHEH_00843 2.2e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHGHIHEH_00844 9.23e-305 - - - EGP - - - Major Facilitator
MHGHIHEH_00845 0.0 pbpC - - M ko:K21467 - ko00000,ko01011 NTF2-like N-terminal transpeptidase domain
MHGHIHEH_00846 1.34e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHGHIHEH_00847 5.72e-214 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
MHGHIHEH_00848 8.01e-197 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHGHIHEH_00849 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHGHIHEH_00850 3.66e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHGHIHEH_00851 2.08e-240 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MHGHIHEH_00852 1.16e-45 - - - - - - - -
MHGHIHEH_00853 0.0 - - - E - - - Amino acid permease
MHGHIHEH_00854 1.56e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHGHIHEH_00855 4.27e-138 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHGHIHEH_00856 1.01e-192 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHGHIHEH_00857 2.08e-106 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
MHGHIHEH_00858 3.99e-165 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHGHIHEH_00859 6.59e-143 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MHGHIHEH_00860 1.56e-310 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHGHIHEH_00861 1.08e-121 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MHGHIHEH_00864 9.77e-144 - - - S ko:K03824 - ko00000,ko01000 Acetyltransferase (GNAT) family
MHGHIHEH_00865 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHGHIHEH_00866 4.75e-307 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MHGHIHEH_00867 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_00868 4.06e-240 - - - E - - - M42 glutamyl aminopeptidase
MHGHIHEH_00869 2.9e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHGHIHEH_00870 2.96e-78 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_00871 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGHIHEH_00872 1.81e-250 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHGHIHEH_00873 1.3e-243 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MHGHIHEH_00874 9.25e-288 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MHGHIHEH_00875 2.72e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_00876 3.66e-187 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_00877 4.68e-206 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_00878 2.29e-107 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_00879 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHGHIHEH_00880 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHGHIHEH_00881 9.78e-112 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MHGHIHEH_00884 2.22e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MHGHIHEH_00885 0.0 cpdA - - S - - - Calcineurin-like phosphoesterase
MHGHIHEH_00886 5.05e-52 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MHGHIHEH_00887 5.58e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MHGHIHEH_00888 4.22e-273 coiA - - S ko:K06198 - ko00000 Competence protein
MHGHIHEH_00889 6.41e-148 yjbH - - Q - - - Thioredoxin
MHGHIHEH_00890 7.28e-138 - - - S - - - CYTH
MHGHIHEH_00891 1.19e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MHGHIHEH_00892 1.05e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHGHIHEH_00893 5.81e-218 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHGHIHEH_00894 9.8e-259 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHGHIHEH_00895 2.24e-148 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MHGHIHEH_00896 1.09e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHGHIHEH_00897 9.35e-254 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MHGHIHEH_00898 1.16e-81 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHGHIHEH_00899 4.12e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHGHIHEH_00900 4.94e-245 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHGHIHEH_00901 1.94e-219 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MHGHIHEH_00902 3.44e-200 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MHGHIHEH_00903 1.86e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHGHIHEH_00904 4.04e-94 - - - S - - - Protein of unknown function (DUF1149)
MHGHIHEH_00905 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHGHIHEH_00906 1.9e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
MHGHIHEH_00907 1.13e-308 ymfH - - S - - - Peptidase M16
MHGHIHEH_00908 3.01e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHGHIHEH_00909 1.15e-169 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MHGHIHEH_00910 9.93e-136 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHGHIHEH_00912 4.1e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MHGHIHEH_00913 3.74e-243 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHGHIHEH_00914 7.95e-317 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MHGHIHEH_00915 1.14e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MHGHIHEH_00916 6.41e-299 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MHGHIHEH_00917 6.13e-104 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MHGHIHEH_00918 3.24e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHGHIHEH_00919 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHGHIHEH_00920 8.69e-239 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHGHIHEH_00921 1.28e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 ABC transporter
MHGHIHEH_00922 1.34e-200 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHGHIHEH_00923 3.16e-258 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MHGHIHEH_00924 1.83e-168 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHGHIHEH_00925 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHGHIHEH_00926 1.76e-196 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHGHIHEH_00927 4.48e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MHGHIHEH_00928 1.06e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MHGHIHEH_00929 9.06e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHGHIHEH_00930 3.54e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHGHIHEH_00931 3.82e-156 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MHGHIHEH_00932 0.0 yvlB - - S - - - Putative adhesin
MHGHIHEH_00933 5.23e-50 - - - - - - - -
MHGHIHEH_00934 3.07e-50 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MHGHIHEH_00935 8.27e-223 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHGHIHEH_00936 7.94e-202 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHGHIHEH_00937 1.48e-248 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MHGHIHEH_00938 1.43e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHGHIHEH_00939 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MHGHIHEH_00940 1.51e-148 - - - T - - - Transcriptional regulatory protein, C terminal
MHGHIHEH_00941 9.33e-222 - - - T - - - His Kinase A (phosphoacceptor) domain
MHGHIHEH_00942 1.47e-118 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_00943 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MHGHIHEH_00944 1.99e-153 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MHGHIHEH_00945 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHGHIHEH_00946 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHGHIHEH_00947 3.63e-111 - - - S - - - Short repeat of unknown function (DUF308)
MHGHIHEH_00948 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MHGHIHEH_00949 2.99e-248 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MHGHIHEH_00950 9.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MHGHIHEH_00951 3.19e-105 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MHGHIHEH_00952 5.97e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHGHIHEH_00955 5.52e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MHGHIHEH_00956 2.1e-247 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHGHIHEH_00957 2.16e-282 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MHGHIHEH_00958 2.81e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHGHIHEH_00959 2.05e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHGHIHEH_00960 5.21e-293 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MHGHIHEH_00961 8.99e-62 - - - - - - - -
MHGHIHEH_00962 0.0 eriC - - P ko:K03281 - ko00000 chloride
MHGHIHEH_00963 5.04e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MHGHIHEH_00964 4.01e-181 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
MHGHIHEH_00965 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHGHIHEH_00966 4.47e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MHGHIHEH_00967 2.21e-226 yvdE - - K - - - helix_turn _helix lactose operon repressor
MHGHIHEH_00968 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MHGHIHEH_00969 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHGHIHEH_00970 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MHGHIHEH_00971 6.75e-153 - 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHGHIHEH_00972 3.7e-21 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHGHIHEH_00973 3.01e-16 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHGHIHEH_00974 2.33e-23 - - - - - - - -
MHGHIHEH_00975 1.13e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MHGHIHEH_00976 1.03e-305 YSH1 - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Metallo-beta-lactamase superfamily
MHGHIHEH_00977 8.67e-312 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHGHIHEH_00978 1.1e-188 malF - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHGHIHEH_00979 7.01e-213 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MHGHIHEH_00980 3.08e-248 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_00981 3.63e-136 - - - K ko:K06977 - ko00000 Acetyltransferase (GNAT) domain
MHGHIHEH_00982 7.57e-119 - - - - - - - -
MHGHIHEH_00983 4e-203 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHGHIHEH_00984 5.91e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHGHIHEH_00985 8.65e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MHGHIHEH_00986 3.18e-106 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MHGHIHEH_00988 1.71e-209 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_00989 2.34e-271 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHGHIHEH_00990 4.66e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHGHIHEH_00991 8.14e-194 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MHGHIHEH_00992 3.2e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MHGHIHEH_00993 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
MHGHIHEH_00994 1.97e-124 - - - K - - - Cupin domain
MHGHIHEH_00995 9.1e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHGHIHEH_00996 1.44e-189 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00997 6.79e-186 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_00998 8.49e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_01000 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
MHGHIHEH_01001 1.05e-143 - - - K - - - Transcriptional regulator
MHGHIHEH_01002 2.68e-240 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_01003 3.66e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHGHIHEH_01004 3.82e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHGHIHEH_01005 5.53e-217 ybbR - - S - - - YbbR-like protein
MHGHIHEH_01006 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHGHIHEH_01007 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHGHIHEH_01009 0.0 pepF2 - - E - - - Oligopeptidase F
MHGHIHEH_01010 2.75e-105 - - - S - - - VanZ like family
MHGHIHEH_01011 5.85e-169 yebC - - K - - - Transcriptional regulatory protein
MHGHIHEH_01012 1.02e-196 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MHGHIHEH_01013 3.76e-217 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MHGHIHEH_01014 1e-35 - - - - ko:K02245 - ko00000,ko00002,ko02044 -
MHGHIHEH_01016 3.32e-32 - - - - - - - -
MHGHIHEH_01017 1.42e-24 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
MHGHIHEH_01019 3.73e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MHGHIHEH_01020 8.54e-81 - - - - - - - -
MHGHIHEH_01021 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MHGHIHEH_01022 7.51e-191 arbV - - I - - - Phosphate acyltransferases
MHGHIHEH_01023 8.22e-212 arbx - - M - - - Glycosyl transferase family 8
MHGHIHEH_01024 2.22e-231 arbY - - M - - - family 8
MHGHIHEH_01025 2.65e-213 arbZ - - I - - - Phosphate acyltransferases
MHGHIHEH_01026 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MHGHIHEH_01028 8.76e-261 lldD 1.13.12.4 - C ko:K00467 ko00620,map00620 ko00000,ko00001,ko01000 IMP dehydrogenase / GMP reductase domain
MHGHIHEH_01029 2.41e-156 ydgI - - C - - - Nitroreductase family
MHGHIHEH_01030 1.92e-202 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MHGHIHEH_01031 3.74e-207 - - - S - - - KR domain
MHGHIHEH_01032 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
MHGHIHEH_01033 2.42e-88 - - - S - - - Belongs to the HesB IscA family
MHGHIHEH_01034 3e-309 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MHGHIHEH_01035 3.91e-159 ciaR - - K ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
MHGHIHEH_01036 3.08e-93 - - - S - - - GtrA-like protein
MHGHIHEH_01037 0.0 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
MHGHIHEH_01038 8.07e-233 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
MHGHIHEH_01039 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MHGHIHEH_01040 1.17e-222 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
MHGHIHEH_01041 3.37e-180 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_01042 5.61e-207 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHGHIHEH_01043 5.43e-209 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_01044 3.06e-213 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
MHGHIHEH_01045 0.0 bglB 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
MHGHIHEH_01046 1.39e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MHGHIHEH_01048 1.94e-251 - - - - - - - -
MHGHIHEH_01049 9.5e-199 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHGHIHEH_01050 1.92e-153 - - - S - - - Psort location Cytoplasmic, score
MHGHIHEH_01051 1.83e-113 - - - S - - - Short repeat of unknown function (DUF308)
MHGHIHEH_01053 1.5e-156 yrkL - - S - - - Flavodoxin-like fold
MHGHIHEH_01054 2.23e-191 - - - I - - - alpha/beta hydrolase fold
MHGHIHEH_01055 3.37e-271 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
MHGHIHEH_01057 7.42e-112 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHGHIHEH_01058 6.8e-21 - - - - - - - -
MHGHIHEH_01059 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MHGHIHEH_01060 1.37e-271 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHGHIHEH_01061 3.73e-150 - - - S - - - HAD hydrolase, family IA, variant
MHGHIHEH_01062 4.13e-181 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
MHGHIHEH_01063 3.58e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
MHGHIHEH_01064 1.3e-121 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
MHGHIHEH_01065 4.19e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
MHGHIHEH_01066 1.75e-225 lacC 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MHGHIHEH_01067 2.22e-160 - - - S - - - Domain of unknown function (DUF4867)
MHGHIHEH_01068 2.82e-36 - - - - - - - -
MHGHIHEH_01069 0.0 gatC - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHGHIHEH_01070 5.42e-67 - 2.7.1.204 - G ko:K20113 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_01071 1.92e-101 - 2.7.1.204 - G ko:K20112 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_01074 5.83e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MHGHIHEH_01075 3.41e-218 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHGHIHEH_01076 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MHGHIHEH_01077 4.24e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MHGHIHEH_01078 3.3e-282 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHGHIHEH_01079 8.48e-172 - - - M - - - Glycosyltransferase like family 2
MHGHIHEH_01080 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHGHIHEH_01081 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MHGHIHEH_01082 1.29e-168 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHGHIHEH_01083 2.99e-144 ung2 - - L - - - Uracil-DNA glycosylase
MHGHIHEH_01084 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
MHGHIHEH_01085 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MHGHIHEH_01089 5.74e-106 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_01092 1.46e-149 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MHGHIHEH_01093 1.23e-153 yqgG - - S ko:K07507 - ko00000,ko02000 MgtC family
MHGHIHEH_01094 3.97e-227 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MHGHIHEH_01095 4.75e-316 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MHGHIHEH_01096 2.05e-203 - - - C - - - nadph quinone reductase
MHGHIHEH_01097 1.06e-69 ybjQ - - S - - - Belongs to the UPF0145 family
MHGHIHEH_01098 7.12e-158 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MHGHIHEH_01099 2.21e-174 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHGHIHEH_01100 7.53e-208 - - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_01101 2.56e-190 - - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MHGHIHEH_01102 1.2e-95 - - - K - - - LytTr DNA-binding domain
MHGHIHEH_01103 2.72e-78 - - - S - - - Protein of unknown function (DUF3021)
MHGHIHEH_01104 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
MHGHIHEH_01105 0.0 - - - S - - - Protein of unknown function (DUF3800)
MHGHIHEH_01106 3.61e-316 yifK - - E ko:K03293 - ko00000 Amino acid permease
MHGHIHEH_01107 6.7e-203 - - - S - - - Aldo/keto reductase family
MHGHIHEH_01109 2.73e-147 ylbE - - GM - - - NAD(P)H-binding
MHGHIHEH_01110 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MHGHIHEH_01111 1.37e-99 - - - O - - - OsmC-like protein
MHGHIHEH_01112 5.77e-87 - - - - - - - -
MHGHIHEH_01113 3.08e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MHGHIHEH_01114 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHGHIHEH_01115 1.13e-221 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
MHGHIHEH_01116 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MHGHIHEH_01117 1.51e-283 sstT - - U ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MHGHIHEH_01118 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_01119 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHGHIHEH_01120 1.56e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MHGHIHEH_01121 3.34e-286 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MHGHIHEH_01122 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_01123 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_01124 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHGHIHEH_01125 7.88e-211 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
MHGHIHEH_01126 2.05e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MHGHIHEH_01127 4.07e-114 - - - S - - - ECF-type riboflavin transporter, S component
MHGHIHEH_01128 3.03e-186 CcmA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_01129 0.0 - - - - - - - -
MHGHIHEH_01130 6.94e-225 yicL - - EG - - - EamA-like transporter family
MHGHIHEH_01131 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MHGHIHEH_01132 1.28e-140 - - - N - - - WxL domain surface cell wall-binding
MHGHIHEH_01133 4.46e-74 - - - - - - - -
MHGHIHEH_01134 1.66e-154 - - - S - - - WxL domain surface cell wall-binding
MHGHIHEH_01135 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MHGHIHEH_01136 1.78e-58 - - - - - - - -
MHGHIHEH_01137 2.01e-224 - - - S - - - Cell surface protein
MHGHIHEH_01138 4.64e-151 - - - S - - - WxL domain surface cell wall-binding
MHGHIHEH_01139 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHGHIHEH_01140 1.92e-44 - - - - - - - -
MHGHIHEH_01141 2.87e-157 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_01142 2.79e-185 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MHGHIHEH_01143 2.02e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHGHIHEH_01144 2.49e-184 - - - - - - - -
MHGHIHEH_01146 1.18e-295 - - - - - - - -
MHGHIHEH_01147 5.39e-65 - - - - - - - -
MHGHIHEH_01148 1.03e-120 - - - L ko:K07474 - ko00000 Terminase small subunit
MHGHIHEH_01149 6.83e-313 - - - S - - - Terminase-like family
MHGHIHEH_01150 0.0 - - - S - - - Phage portal protein
MHGHIHEH_01151 6.8e-227 - - - S - - - head morphogenesis protein, SPP1 gp7 family
MHGHIHEH_01154 8.26e-105 - - - S - - - Domain of unknown function (DUF4355)
MHGHIHEH_01155 6.27e-67 - - - - - - - -
MHGHIHEH_01156 1.37e-246 - - - S - - - Phage major capsid protein E
MHGHIHEH_01157 1.02e-38 - - - - - - - -
MHGHIHEH_01158 1.14e-229 - - - - - - - -
MHGHIHEH_01159 6.46e-83 - - - S - - - Phage gp6-like head-tail connector protein
MHGHIHEH_01160 7.78e-66 - - - - - - - -
MHGHIHEH_01161 1.17e-70 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MHGHIHEH_01162 2.75e-91 - - - S - - - Protein of unknown function (DUF3168)
MHGHIHEH_01163 5.94e-134 - - - S - - - Phage tail tube protein
MHGHIHEH_01164 3.3e-47 - - - S - - - Phage tail assembly chaperone protein, TAC
MHGHIHEH_01165 1.57e-73 - - - - - - - -
MHGHIHEH_01166 0.0 - - - S - - - phage tail tape measure protein
MHGHIHEH_01167 2.4e-188 - - - S - - - Phage tail protein
MHGHIHEH_01168 2.83e-193 - - - S - - - cellulase activity
MHGHIHEH_01169 1.09e-13 - - - - - - - -
MHGHIHEH_01171 1.72e-83 - - - - - - - -
MHGHIHEH_01173 1.98e-84 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
MHGHIHEH_01174 6.97e-227 - - - M - - - Glycosyl hydrolases family 25
MHGHIHEH_01175 5.83e-177 - - - S - - - Domain of unknown function DUF1829
MHGHIHEH_01176 2.12e-63 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
MHGHIHEH_01178 3.82e-194 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MHGHIHEH_01179 5.49e-71 - - - S - - - Pfam Transposase IS66
MHGHIHEH_01180 1.87e-292 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferases group 1
MHGHIHEH_01181 3.64e-219 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
MHGHIHEH_01182 5.68e-110 guaD - - FJ - - - MafB19-like deaminase
MHGHIHEH_01185 4.26e-103 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
MHGHIHEH_01186 1.53e-19 - - - - - - - -
MHGHIHEH_01187 3.11e-271 yttB - - EGP - - - Major Facilitator
MHGHIHEH_01188 4.36e-136 - - - S - - - Protein of unknown function (DUF1211)
MHGHIHEH_01189 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHGHIHEH_01192 4.1e-163 pgm7 - - G - - - Phosphoglycerate mutase family
MHGHIHEH_01193 6.41e-155 - - - K - - - Bacterial regulatory proteins, tetR family
MHGHIHEH_01194 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_01195 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHGHIHEH_01196 7.15e-179 - - - S - - - NADPH-dependent FMN reductase
MHGHIHEH_01197 1.07e-207 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MHGHIHEH_01198 1.24e-249 ampC - - V - - - Beta-lactamase
MHGHIHEH_01199 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MHGHIHEH_01200 4.41e-143 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MHGHIHEH_01201 8.62e-252 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHGHIHEH_01202 2.32e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHGHIHEH_01203 4.89e-238 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHGHIHEH_01204 2.13e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHGHIHEH_01205 3.05e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHGHIHEH_01206 1.23e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MHGHIHEH_01207 2.57e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHGHIHEH_01208 1.13e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHGHIHEH_01209 3.37e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHGHIHEH_01210 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHGHIHEH_01211 1.92e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHGHIHEH_01212 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHGHIHEH_01213 1.88e-91 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MHGHIHEH_01214 8.38e-42 - - - S - - - Protein of unknown function (DUF1146)
MHGHIHEH_01215 4.12e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MHGHIHEH_01216 1.37e-26 - - - S - - - DNA-directed RNA polymerase subunit beta
MHGHIHEH_01217 1.14e-72 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MHGHIHEH_01218 8.37e-42 - - - S - - - Protein of unknown function (DUF2969)
MHGHIHEH_01219 1.41e-285 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MHGHIHEH_01220 4.19e-65 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MHGHIHEH_01221 1.88e-268 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MHGHIHEH_01222 3.79e-186 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHGHIHEH_01224 8.04e-192 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHGHIHEH_01225 2.09e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHGHIHEH_01226 5.35e-149 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_01227 4.15e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MHGHIHEH_01228 3.88e-243 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MHGHIHEH_01229 4.87e-280 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHGHIHEH_01230 4.94e-103 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MHGHIHEH_01231 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MHGHIHEH_01232 4.73e-31 - - - - - - - -
MHGHIHEH_01233 9.85e-88 - - - S - - - Protein of unknown function (DUF1694)
MHGHIHEH_01234 3.03e-231 - - - S - - - Protein of unknown function (DUF2785)
MHGHIHEH_01235 2.13e-149 yhfA - - S - - - HAD hydrolase, family IA, variant 3
MHGHIHEH_01236 2.7e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
MHGHIHEH_01237 2.86e-108 uspA - - T - - - universal stress protein
MHGHIHEH_01238 1.65e-52 - - - - - - - -
MHGHIHEH_01239 1.66e-306 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MHGHIHEH_01240 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MHGHIHEH_01241 1.13e-98 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MHGHIHEH_01242 5.99e-143 yktB - - S - - - Belongs to the UPF0637 family
MHGHIHEH_01243 1.02e-158 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MHGHIHEH_01244 4.62e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MHGHIHEH_01245 1.89e-157 - - - G - - - alpha-ribazole phosphatase activity
MHGHIHEH_01246 2.82e-197 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHGHIHEH_01247 1.66e-218 - - - IQ - - - NAD dependent epimerase/dehydratase family
MHGHIHEH_01248 2.93e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MHGHIHEH_01249 2.05e-173 - - - F - - - deoxynucleoside kinase
MHGHIHEH_01250 8.16e-203 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
MHGHIHEH_01251 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHGHIHEH_01252 3.55e-202 - - - T - - - GHKL domain
MHGHIHEH_01253 2.69e-156 - - - T - - - Transcriptional regulatory protein, C terminal
MHGHIHEH_01254 1.17e-217 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHGHIHEH_01255 1.8e-142 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHGHIHEH_01256 3.45e-206 - - - K - - - Transcriptional regulator
MHGHIHEH_01257 1.11e-101 yphH - - S - - - Cupin domain
MHGHIHEH_01258 1.07e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MHGHIHEH_01259 2.72e-149 - - - GM - - - NAD(P)H-binding
MHGHIHEH_01260 1.94e-54 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHGHIHEH_01261 2.25e-156 gst 2.5.1.18 - O ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 ko00000,ko00001,ko01000,ko02000 Glutathione S-transferase, C-terminal domain
MHGHIHEH_01262 1.5e-142 - - - K - - - Psort location Cytoplasmic, score
MHGHIHEH_01263 1.65e-211 - - - K - - - Acetyltransferase (GNAT) domain
MHGHIHEH_01264 4.14e-113 - - - K - - - Acetyltransferase (GNAT) domain
MHGHIHEH_01265 8.05e-197 degV - - S - - - Uncharacterised protein, DegV family COG1307
MHGHIHEH_01266 2.07e-135 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MHGHIHEH_01267 2.43e-264 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHGHIHEH_01268 1.17e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MHGHIHEH_01269 1.63e-201 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_01270 2.98e-272 - - - - - - - -
MHGHIHEH_01271 1.41e-84 - - - K - - - helix_turn_helix, mercury resistance
MHGHIHEH_01272 1.1e-62 - - - S - - - Protein of unknown function (DUF2568)
MHGHIHEH_01273 2.93e-143 - - - S - - - Protein of unknown function C-terminus (DUF2399)
MHGHIHEH_01274 8.42e-156 - - - K - - - Acetyltransferase (GNAT) domain
MHGHIHEH_01275 1.23e-57 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MHGHIHEH_01276 1.2e-60 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
MHGHIHEH_01278 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MHGHIHEH_01279 2.56e-89 - - - K - - - Cro/C1-type HTH DNA-binding domain
MHGHIHEH_01281 0.0 - - - - - - - -
MHGHIHEH_01282 2.84e-63 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
MHGHIHEH_01283 1.35e-88 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
MHGHIHEH_01284 5.76e-14 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHGHIHEH_01285 2.79e-213 - - - S - - - Putative esterase
MHGHIHEH_01286 1.83e-256 - - - - - - - -
MHGHIHEH_01287 1.47e-136 - - - K - - - Transcriptional regulator, MarR family
MHGHIHEH_01288 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MHGHIHEH_01289 3.85e-108 - - - F - - - NUDIX domain
MHGHIHEH_01290 1.91e-167 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHGHIHEH_01291 4.74e-30 - - - - - - - -
MHGHIHEH_01292 1.09e-209 - - - S - - - zinc-ribbon domain
MHGHIHEH_01293 2.41e-261 pbpX - - V - - - Beta-lactamase
MHGHIHEH_01294 4.01e-240 ydbI - - K - - - AI-2E family transporter
MHGHIHEH_01295 4.31e-166 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MHGHIHEH_01296 1.41e-85 gtcA2 - - S - - - Teichoic acid glycosylation protein
MHGHIHEH_01297 7.62e-219 - - - I - - - Diacylglycerol kinase catalytic domain
MHGHIHEH_01298 0.0 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHGHIHEH_01299 3.51e-216 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MHGHIHEH_01300 5.82e-189 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MHGHIHEH_01301 9.19e-285 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MHGHIHEH_01302 1.63e-175 sfsA - - S ko:K06206 - ko00000 Belongs to the SfsA family
MHGHIHEH_01303 2.6e-96 usp1 - - T - - - Universal stress protein family
MHGHIHEH_01304 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MHGHIHEH_01305 4.1e-191 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHGHIHEH_01306 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MHGHIHEH_01307 1.6e-290 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MHGHIHEH_01308 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHGHIHEH_01309 1.86e-269 floL - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 SPFH domain / Band 7 family
MHGHIHEH_01310 2.67e-51 - - - - - - - -
MHGHIHEH_01311 1.23e-221 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MHGHIHEH_01312 1.54e-220 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHGHIHEH_01313 3.99e-278 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHGHIHEH_01314 1.21e-65 - - - - - - - -
MHGHIHEH_01315 3.67e-163 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
MHGHIHEH_01316 6.61e-93 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MHGHIHEH_01317 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHGHIHEH_01319 6.08e-256 - - - S - - - Calcineurin-like phosphoesterase
MHGHIHEH_01320 9.76e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MHGHIHEH_01321 2.67e-225 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHGHIHEH_01322 1.92e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHGHIHEH_01323 9.96e-212 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MHGHIHEH_01324 2.05e-277 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHGHIHEH_01325 6.81e-86 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MHGHIHEH_01326 9.19e-209 CcmA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_01327 3.68e-144 - - - I - - - ABC-2 family transporter protein
MHGHIHEH_01328 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
MHGHIHEH_01329 9.75e-256 ald1 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MHGHIHEH_01330 2.06e-236 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHGHIHEH_01331 0.0 - - - S - - - OPT oligopeptide transporter protein
MHGHIHEH_01332 3.4e-82 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
MHGHIHEH_01333 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHGHIHEH_01334 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MHGHIHEH_01335 6.16e-316 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MHGHIHEH_01336 2.23e-119 - - - K ko:K18939 - ko00000,ko00002,ko03000 Bacterial regulatory proteins, tetR family
MHGHIHEH_01337 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHGHIHEH_01338 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_01339 3.99e-197 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHGHIHEH_01340 0.0 msbA9 - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MHGHIHEH_01341 0.0 cydD1 - - CO ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MHGHIHEH_01342 2.59e-97 - - - S - - - NusG domain II
MHGHIHEH_01343 1.35e-208 - - - M - - - Peptidoglycan-binding domain 1 protein
MHGHIHEH_01344 1.01e-151 - - - S - - - CRISPR-associated protein (Cas_Csn2)
MHGHIHEH_01345 2.84e-62 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHGHIHEH_01346 9.98e-215 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHGHIHEH_01347 2.31e-308 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MHGHIHEH_01348 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MHGHIHEH_01349 6.56e-181 - - - - - - - -
MHGHIHEH_01350 3.11e-274 - - - S - - - Membrane
MHGHIHEH_01351 1.12e-82 - - - S - - - Protein of unknown function (DUF1093)
MHGHIHEH_01352 6.43e-66 - - - - - - - -
MHGHIHEH_01353 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MHGHIHEH_01354 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MHGHIHEH_01355 5.88e-232 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MHGHIHEH_01356 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MHGHIHEH_01358 1.12e-301 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
MHGHIHEH_01359 1.79e-243 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MHGHIHEH_01360 6.98e-53 - - - - - - - -
MHGHIHEH_01361 7.07e-112 - - - - - - - -
MHGHIHEH_01362 6.71e-34 - - - - - - - -
MHGHIHEH_01363 1.72e-213 - - - EG - - - EamA-like transporter family
MHGHIHEH_01364 3.45e-144 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MHGHIHEH_01365 9.59e-101 usp5 - - T - - - universal stress protein
MHGHIHEH_01366 3.25e-74 - - - K - - - Helix-turn-helix domain
MHGHIHEH_01367 2.13e-185 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MHGHIHEH_01368 5.06e-282 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
MHGHIHEH_01369 1.54e-84 - - - - - - - -
MHGHIHEH_01370 7.09e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MHGHIHEH_01371 5.77e-93 adhR - - K - - - helix_turn_helix, mercury resistance
MHGHIHEH_01372 2.59e-107 - - - C - - - Flavodoxin
MHGHIHEH_01373 2.68e-253 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MHGHIHEH_01374 1.59e-147 - - - GM - - - NmrA-like family
MHGHIHEH_01376 5.62e-132 - - - Q - - - methyltransferase
MHGHIHEH_01377 9.78e-139 - - - T - - - Sh3 type 3 domain protein
MHGHIHEH_01378 6.72e-152 - - - F - - - glutamine amidotransferase
MHGHIHEH_01379 1.23e-172 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
MHGHIHEH_01380 0.0 yhdP - - S - - - Transporter associated domain
MHGHIHEH_01381 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MHGHIHEH_01382 8.38e-80 - - - S - - - Domain of unknown function (DUF4811)
MHGHIHEH_01383 1.95e-127 maf - - D ko:K06287 - ko00000 nucleoside-triphosphate diphosphatase activity
MHGHIHEH_01384 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHGHIHEH_01385 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHGHIHEH_01386 0.0 ydaO - - E - - - amino acid
MHGHIHEH_01387 6.55e-75 - - - S - - - Domain of unknown function (DUF1827)
MHGHIHEH_01388 1.44e-175 ypaC - - Q - - - Methyltransferase domain
MHGHIHEH_01389 0.0 - - - S - - - ABC transporter
MHGHIHEH_01390 2.04e-224 draG - - O - - - ADP-ribosylglycohydrolase
MHGHIHEH_01391 1.26e-139 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHGHIHEH_01393 4.42e-54 - - - - - - - -
MHGHIHEH_01394 8.9e-174 - - - S - - - Protein of unknown function (DUF975)
MHGHIHEH_01395 2.32e-188 - - - M - - - Glycosyltransferase like family 2
MHGHIHEH_01396 1.55e-173 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MHGHIHEH_01397 4.9e-103 - - - T - - - Sh3 type 3 domain protein
MHGHIHEH_01398 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHGHIHEH_01399 3.42e-240 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHGHIHEH_01400 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MHGHIHEH_01401 1.52e-205 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MHGHIHEH_01402 6.01e-211 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MHGHIHEH_01403 6.97e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MHGHIHEH_01404 5.86e-167 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHGHIHEH_01405 3.74e-75 - - - - - - - -
MHGHIHEH_01406 3.1e-268 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MHGHIHEH_01407 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MHGHIHEH_01408 5.16e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MHGHIHEH_01409 1.8e-186 gntR - - K - - - rpiR family
MHGHIHEH_01410 8.67e-88 yodA - - S - - - Tautomerase enzyme
MHGHIHEH_01411 4.69e-203 iolJ 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHGHIHEH_01412 1.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MHGHIHEH_01413 3.37e-249 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MHGHIHEH_01414 9.62e-247 - 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
MHGHIHEH_01415 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MHGHIHEH_01416 6.58e-228 iolC 2.7.1.92 - H ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MHGHIHEH_01417 8.47e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MHGHIHEH_01418 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHGHIHEH_01419 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHGHIHEH_01420 7.14e-187 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MHGHIHEH_01421 1.36e-209 yvgN - - C - - - Aldo keto reductase
MHGHIHEH_01422 2.23e-181 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MHGHIHEH_01423 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHGHIHEH_01424 1.02e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHGHIHEH_01425 1.85e-301 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHGHIHEH_01426 2.81e-278 hpk31 - - T - - - Histidine kinase
MHGHIHEH_01427 1.68e-156 vanR - - K - - - response regulator
MHGHIHEH_01428 2.05e-156 - - - - - - - -
MHGHIHEH_01429 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHGHIHEH_01430 8.29e-168 - - - S - - - Protein of unknown function (DUF1129)
MHGHIHEH_01431 9.76e-237 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHGHIHEH_01432 3.26e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MHGHIHEH_01433 1.11e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHGHIHEH_01434 1.49e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MHGHIHEH_01435 7.98e-188 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHGHIHEH_01436 2.27e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MHGHIHEH_01437 4.01e-87 - - - - - - - -
MHGHIHEH_01438 1.35e-164 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MHGHIHEH_01439 6.15e-139 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MHGHIHEH_01440 6.93e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHGHIHEH_01441 1.42e-195 - - - S - - - Protein of unknown function (DUF979)
MHGHIHEH_01442 2.66e-147 - - - S - - - Protein of unknown function (DUF969)
MHGHIHEH_01443 1.97e-92 asp2 - - S - - - Asp23 family, cell envelope-related function
MHGHIHEH_01444 8.12e-90 asp23 - - S - - - Asp23 family, cell envelope-related function
MHGHIHEH_01445 4.15e-34 - - - - - - - -
MHGHIHEH_01446 1.16e-112 - - - S - - - Protein conserved in bacteria
MHGHIHEH_01447 1.93e-52 - - - S - - - Transglycosylase associated protein
MHGHIHEH_01448 2.27e-94 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MHGHIHEH_01449 2.86e-219 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHGHIHEH_01450 2.82e-36 - - - - - - - -
MHGHIHEH_01451 5.54e-50 - - - - - - - -
MHGHIHEH_01452 1.63e-109 - - - C - - - Flavodoxin
MHGHIHEH_01453 4.85e-65 - - - - - - - -
MHGHIHEH_01454 5.12e-117 - - - - - - - -
MHGHIHEH_01455 1.47e-07 - - - - - - - -
MHGHIHEH_01456 6.45e-74 ywjH - - S - - - Protein of unknown function (DUF1634)
MHGHIHEH_01457 1.02e-176 yunE - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
MHGHIHEH_01458 6.38e-282 - - - S ko:K06872 - ko00000 TPM domain
MHGHIHEH_01459 6.18e-150 - - - - - - - -
MHGHIHEH_01460 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MHGHIHEH_01461 0.0 fnq20 - - S - - - FAD-NAD(P)-binding
MHGHIHEH_01462 2.53e-141 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
MHGHIHEH_01463 3.37e-285 - - - V - - - ABC transporter transmembrane region
MHGHIHEH_01464 7.09e-274 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
MHGHIHEH_01465 4.15e-103 - - - S - - - NUDIX domain
MHGHIHEH_01466 7.76e-56 - - - - - - - -
MHGHIHEH_01467 6.97e-115 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_01468 1.37e-91 - - - - - - - -
MHGHIHEH_01469 2.97e-66 - - - - - - - -
MHGHIHEH_01470 6.63e-128 - - - - - - - -
MHGHIHEH_01471 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHGHIHEH_01472 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MHGHIHEH_01474 0.0 bmr3 - - EGP - - - Major Facilitator
MHGHIHEH_01475 4.77e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
MHGHIHEH_01476 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
MHGHIHEH_01477 4.22e-60 - - - S - - - Thiamine-binding protein
MHGHIHEH_01478 5.47e-178 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MHGHIHEH_01479 4.73e-204 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MHGHIHEH_01480 1.07e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHGHIHEH_01481 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MHGHIHEH_01482 1.1e-76 - - - - - - - -
MHGHIHEH_01483 1.36e-221 - - - S - - - Protein of unknown function (DUF805)
MHGHIHEH_01484 0.0 - - - L - - - Mga helix-turn-helix domain
MHGHIHEH_01486 8.11e-241 ynjC - - S - - - Cell surface protein
MHGHIHEH_01487 2.04e-171 - - - S - - - WxL domain surface cell wall-binding
MHGHIHEH_01488 2e-167 - - - S - - - WxL domain surface cell wall-binding
MHGHIHEH_01490 0.0 - - - - - - - -
MHGHIHEH_01491 1.22e-133 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHGHIHEH_01492 6.64e-39 - - - - - - - -
MHGHIHEH_01493 1.01e-228 mhqA - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHGHIHEH_01495 2.61e-124 - - - K - - - LysR substrate binding domain
MHGHIHEH_01496 1.86e-252 - - - S ko:K07112 - ko00000 Sulphur transport
MHGHIHEH_01497 0.0 - - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHGHIHEH_01498 2.13e-169 - - - E - - - lipolytic protein G-D-S-L family
MHGHIHEH_01499 7.89e-184 epsB - - M - - - biosynthesis protein
MHGHIHEH_01500 1.2e-161 ywqD - - D - - - Capsular exopolysaccharide family
MHGHIHEH_01501 3.64e-293 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
MHGHIHEH_01502 1.78e-261 - - - M - - - Glycosyl transferases group 1
MHGHIHEH_01503 2.26e-176 - - - M - - - Glycosyltransferase like family 2
MHGHIHEH_01504 1.82e-207 - - - S - - - O-antigen ligase like membrane protein
MHGHIHEH_01505 1.07e-139 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MHGHIHEH_01506 7.88e-306 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MHGHIHEH_01507 1.88e-176 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MHGHIHEH_01508 6.81e-93 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MHGHIHEH_01509 1.53e-208 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHGHIHEH_01510 1.55e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MHGHIHEH_01511 5.88e-259 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHGHIHEH_01512 2.16e-203 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHGHIHEH_01513 5.65e-201 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHGHIHEH_01514 1.15e-185 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MHGHIHEH_01515 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
MHGHIHEH_01516 1.94e-86 spx2 - - P ko:K16509 - ko00000 ArsC family
MHGHIHEH_01517 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
MHGHIHEH_01518 1.12e-95 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
MHGHIHEH_01519 1.29e-186 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHGHIHEH_01520 5.44e-132 - - - M - - - Sortase family
MHGHIHEH_01521 8.73e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MHGHIHEH_01522 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHGHIHEH_01523 1.18e-255 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHGHIHEH_01524 1.39e-279 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MHGHIHEH_01525 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHGHIHEH_01526 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHGHIHEH_01527 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHGHIHEH_01528 3.12e-222 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHGHIHEH_01529 5.83e-73 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHGHIHEH_01530 1.87e-221 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHGHIHEH_01531 1.55e-312 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHGHIHEH_01532 2.08e-187 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MHGHIHEH_01533 6.72e-88 - - - K - - - Acetyltransferase (GNAT) domain
MHGHIHEH_01534 7.28e-144 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MHGHIHEH_01535 9.35e-15 - - - - - - - -
MHGHIHEH_01536 3.91e-109 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MHGHIHEH_01538 1.89e-228 - - - - - - - -
MHGHIHEH_01539 6.35e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_01540 8.33e-189 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHGHIHEH_01541 5.85e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_01542 6.51e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_01543 2.5e-191 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MHGHIHEH_01544 1.58e-125 - - - V - - - Beta-lactamase
MHGHIHEH_01545 7.23e-126 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHGHIHEH_01546 3.77e-12 - - - I - - - Acyltransferase family
MHGHIHEH_01547 1.71e-64 - - - - - - - -
MHGHIHEH_01548 8.61e-72 - - - S - - - ErfK ybiS ycfS ynhG family protein
MHGHIHEH_01550 1.37e-249 cps2E - - M - - - Bacterial sugar transferase
MHGHIHEH_01551 7.04e-106 wcaA - - M - - - Glycosyl transferase family 2
MHGHIHEH_01552 5.14e-147 licD3 - - M ko:K07271 - ko00000,ko01000 LicD family
MHGHIHEH_01553 6.19e-132 - 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
MHGHIHEH_01554 1e-152 - 4.2.1.46 - GM ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Male sterility protein
MHGHIHEH_01555 6.35e-123 - - - M - - - group 2 family protein
MHGHIHEH_01556 2.47e-185 cps2I - - S - - - Psort location CytoplasmicMembrane, score
MHGHIHEH_01557 1.01e-98 - - - M - - - Glycosyl transferases group 1
MHGHIHEH_01558 1.32e-74 - - - M - - - O-Antigen ligase
MHGHIHEH_01559 4.88e-139 - - - M - - - Glycosyl hydrolases family 25
MHGHIHEH_01560 5.76e-60 - - - M - - - NLP P60 protein
MHGHIHEH_01561 7.36e-34 - - - S - - - Acyltransferase family
MHGHIHEH_01562 5.31e-169 nodB3 - - G - - - Polysaccharide deacetylase
MHGHIHEH_01563 4.57e-304 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHGHIHEH_01564 5.76e-210 - - - I - - - Diacylglycerol kinase catalytic domain
MHGHIHEH_01565 0.0 - - - E - - - Amino Acid
MHGHIHEH_01566 2.68e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_01567 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MHGHIHEH_01568 4.03e-164 gpm2 - - G - - - Phosphoglycerate mutase family
MHGHIHEH_01569 5.73e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MHGHIHEH_01570 6.29e-307 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHGHIHEH_01571 4.52e-106 yjhE - - S - - - Phage tail protein
MHGHIHEH_01572 1.97e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MHGHIHEH_01573 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MHGHIHEH_01574 1.51e-29 - - - - - - - -
MHGHIHEH_01575 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHGHIHEH_01576 5.02e-110 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
MHGHIHEH_01577 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHGHIHEH_01578 1.13e-54 - - - - - - - -
MHGHIHEH_01580 8.03e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MHGHIHEH_01581 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MHGHIHEH_01582 9.84e-246 - - - O - - - AAA domain (Cdc48 subfamily)
MHGHIHEH_01583 9.42e-174 - - - - - - - -
MHGHIHEH_01584 2.68e-75 - - - S - - - Phage derived protein Gp49-like (DUF891)
MHGHIHEH_01585 3.31e-10 - - - K - - - Helix-turn-helix domain
MHGHIHEH_01586 1.47e-27 - - - K - - - Helix-turn-helix domain
MHGHIHEH_01590 8.07e-126 - - - K - - - Transcriptional regulator, AbiEi antitoxin
MHGHIHEH_01591 3.72e-09 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
MHGHIHEH_01592 1.18e-88 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MHGHIHEH_01593 2.13e-254 - - - V - - - efflux transmembrane transporter activity
MHGHIHEH_01594 1.48e-246 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHGHIHEH_01595 1.4e-133 lemA - - S ko:K03744 - ko00000 LemA family
MHGHIHEH_01596 7.19e-157 - - - S ko:K06872 - ko00000 TPM domain
MHGHIHEH_01597 5.58e-306 dinF - - V - - - MatE
MHGHIHEH_01598 6.5e-119 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MHGHIHEH_01599 5.94e-198 - - - Q - - - Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
MHGHIHEH_01600 1.74e-224 ydhF - - S - - - Aldo keto reductase
MHGHIHEH_01601 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MHGHIHEH_01602 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MHGHIHEH_01603 2.57e-223 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MHGHIHEH_01604 3.25e-203 ypuA - - S - - - Protein of unknown function (DUF1002)
MHGHIHEH_01605 6.68e-50 - - - - - - - -
MHGHIHEH_01606 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MHGHIHEH_01608 5.59e-220 - - - - - - - -
MHGHIHEH_01609 2.62e-23 - - - - - - - -
MHGHIHEH_01610 5.67e-165 cobB - - K ko:K12410 - ko00000,ko01000 Sir2 family
MHGHIHEH_01611 9.14e-139 yiiE - - S - - - Protein of unknown function (DUF1211)
MHGHIHEH_01612 3.11e-218 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MHGHIHEH_01613 1.09e-118 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MHGHIHEH_01614 1.7e-195 yunF - - F - - - Protein of unknown function DUF72
MHGHIHEH_01615 1.67e-222 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MHGHIHEH_01616 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHGHIHEH_01617 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHGHIHEH_01618 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHGHIHEH_01619 2.89e-199 - - - T - - - GHKL domain
MHGHIHEH_01620 1.32e-156 - - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHGHIHEH_01621 1.22e-220 yqhA - - G - - - Aldose 1-epimerase
MHGHIHEH_01622 1.35e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
MHGHIHEH_01623 4.26e-103 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
MHGHIHEH_01624 9.1e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MHGHIHEH_01625 6.78e-130 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHGHIHEH_01626 5.84e-202 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHGHIHEH_01627 2.39e-50 veg - - S - - - Biofilm formation stimulator VEG
MHGHIHEH_01628 1.28e-229 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHGHIHEH_01629 1.99e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MHGHIHEH_01630 5.89e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MHGHIHEH_01631 1.29e-154 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_01632 1.18e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MHGHIHEH_01633 1.15e-282 ysaA - - V - - - RDD family
MHGHIHEH_01634 1.34e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHGHIHEH_01635 2.2e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHGHIHEH_01636 1.54e-73 nudA - - S - - - ASCH
MHGHIHEH_01637 5.62e-103 - - - E - - - glutamate:sodium symporter activity
MHGHIHEH_01638 1.31e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHGHIHEH_01639 4.32e-237 - - - S - - - DUF218 domain
MHGHIHEH_01640 1.41e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MHGHIHEH_01641 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MHGHIHEH_01642 1.63e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
MHGHIHEH_01643 3.48e-103 ywiB - - S - - - Domain of unknown function (DUF1934)
MHGHIHEH_01644 1.15e-111 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHGHIHEH_01645 3.42e-202 ybbB - - S - - - Protein of unknown function (DUF1211)
MHGHIHEH_01646 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHGHIHEH_01647 1.35e-299 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHGHIHEH_01648 2.28e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MHGHIHEH_01649 2.29e-87 - - - - - - - -
MHGHIHEH_01650 3.04e-162 - - - - - - - -
MHGHIHEH_01651 4.18e-157 - - - S - - - Tetratricopeptide repeat
MHGHIHEH_01652 3.44e-08 - - - - - - - -
MHGHIHEH_01653 4.87e-187 - - - - - - - -
MHGHIHEH_01654 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHGHIHEH_01655 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHGHIHEH_01656 2.63e-82 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHGHIHEH_01657 1.62e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHGHIHEH_01658 4.66e-44 - - - - - - - -
MHGHIHEH_01659 5.68e-83 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MHGHIHEH_01660 1.63e-111 queT - - S - - - QueT transporter
MHGHIHEH_01661 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
MHGHIHEH_01662 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MHGHIHEH_01663 1.19e-168 yciB - - M - - - ErfK YbiS YcfS YnhG
MHGHIHEH_01664 1.34e-154 - - - S - - - (CBS) domain
MHGHIHEH_01665 0.0 - - - S - - - Putative peptidoglycan binding domain
MHGHIHEH_01666 5.04e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MHGHIHEH_01667 4.28e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHGHIHEH_01668 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHGHIHEH_01669 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MHGHIHEH_01670 1.99e-53 yabO - - J - - - S4 domain protein
MHGHIHEH_01671 7.17e-87 divIC - - D ko:K05589,ko:K13052 - ko00000,ko03036 cell cycle
MHGHIHEH_01672 1.17e-105 yabR - - J ko:K07571 - ko00000 RNA binding
MHGHIHEH_01673 7.68e-310 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHGHIHEH_01674 1.14e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MHGHIHEH_01675 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHGHIHEH_01676 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MHGHIHEH_01677 2.28e-248 - - - S - - - Protein of unknown function C-terminal (DUF3324)
MHGHIHEH_01678 2.27e-241 - - - S - - - Bacterial protein of unknown function (DUF916)
MHGHIHEH_01679 8.79e-208 - - - S - - - WxL domain surface cell wall-binding
MHGHIHEH_01680 4.2e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHGHIHEH_01681 4.37e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHGHIHEH_01682 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MHGHIHEH_01684 2.98e-227 - - - K - - - DNA-binding helix-turn-helix protein
MHGHIHEH_01685 6.77e-77 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MHGHIHEH_01686 2.7e-62 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
MHGHIHEH_01687 8.16e-54 - - - - - - - -
MHGHIHEH_01688 9.58e-244 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MHGHIHEH_01690 2.67e-71 - - - - - - - -
MHGHIHEH_01691 1.79e-104 - - - - - - - -
MHGHIHEH_01692 1.93e-265 XK27_05220 - - S - - - AI-2E family transporter
MHGHIHEH_01693 1.58e-33 - - - - - - - -
MHGHIHEH_01694 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHGHIHEH_01695 2.18e-60 - - - - - - - -
MHGHIHEH_01696 1.71e-213 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MHGHIHEH_01697 1.45e-116 - - - S - - - Flavin reductase like domain
MHGHIHEH_01698 9.67e-91 - - - - - - - -
MHGHIHEH_01699 6.56e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHGHIHEH_01700 1.7e-81 yeaO - - S - - - Protein of unknown function, DUF488
MHGHIHEH_01701 2.2e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MHGHIHEH_01702 1.7e-201 mleR - - K - - - LysR family
MHGHIHEH_01703 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MHGHIHEH_01704 3.58e-217 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MHGHIHEH_01705 8.23e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHGHIHEH_01706 4.6e-113 - - - C - - - FMN binding
MHGHIHEH_01707 0.0 pepF - - E - - - Oligopeptidase F
MHGHIHEH_01708 3.86e-78 - - - - - - - -
MHGHIHEH_01709 3.81e-170 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGHIHEH_01710 1.16e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MHGHIHEH_01711 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MHGHIHEH_01712 7.43e-229 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 carboxylic ester hydrolase activity
MHGHIHEH_01713 1.69e-58 - - - - - - - -
MHGHIHEH_01714 1.4e-121 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHGHIHEH_01715 1.14e-255 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHGHIHEH_01716 7.46e-157 XK27_05175 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MHGHIHEH_01717 2.24e-101 - - - K - - - Transcriptional regulator
MHGHIHEH_01718 2.4e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
MHGHIHEH_01719 3.83e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MHGHIHEH_01720 3.58e-199 dkgB - - S - - - reductase
MHGHIHEH_01721 4.76e-201 - - - - - - - -
MHGHIHEH_01722 1.02e-197 - - - S - - - Alpha beta hydrolase
MHGHIHEH_01723 7.76e-152 yviA - - S - - - Protein of unknown function (DUF421)
MHGHIHEH_01724 1.28e-33 - - - S - - - Protein of unknown function (DUF3290)
MHGHIHEH_01725 5.92e-284 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MHGHIHEH_01726 1.69e-112 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHGHIHEH_01727 1.3e-136 yjbF - - S - - - SNARE associated Golgi protein
MHGHIHEH_01728 8.46e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHGHIHEH_01729 4.54e-241 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHGHIHEH_01730 7.52e-263 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHGHIHEH_01731 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHGHIHEH_01732 5.25e-87 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MHGHIHEH_01733 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MHGHIHEH_01734 2.06e-150 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
MHGHIHEH_01735 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHGHIHEH_01736 4.19e-263 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHGHIHEH_01737 1.13e-307 ytoI - - K - - - DRTGG domain
MHGHIHEH_01738 3.03e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MHGHIHEH_01739 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHGHIHEH_01740 4.44e-223 - - - - - - - -
MHGHIHEH_01741 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHGHIHEH_01743 4.89e-58 yrzL - - S - - - Belongs to the UPF0297 family
MHGHIHEH_01744 2.67e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHGHIHEH_01745 1.3e-69 yrzB - - S - - - Belongs to the UPF0473 family
MHGHIHEH_01746 2.84e-48 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHGHIHEH_01747 1.89e-119 cvpA - - S - - - Colicin V production protein
MHGHIHEH_01748 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHGHIHEH_01749 3.64e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHGHIHEH_01750 1.04e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MHGHIHEH_01751 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGHIHEH_01752 9.86e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MHGHIHEH_01753 6.97e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGHIHEH_01754 2.89e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHGHIHEH_01755 6.77e-111 yslB - - S - - - Protein of unknown function (DUF2507)
MHGHIHEH_01756 0.0 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MHGHIHEH_01757 4.7e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MHGHIHEH_01758 5.44e-175 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
MHGHIHEH_01759 9.32e-112 ykuL - - S - - - CBS domain
MHGHIHEH_01760 4.63e-199 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
MHGHIHEH_01761 6.86e-198 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MHGHIHEH_01762 1.49e-46 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHGHIHEH_01763 4.84e-114 ytxH - - S - - - YtxH-like protein
MHGHIHEH_01764 7.49e-117 yrxA - - S ko:K07105 - ko00000 3H domain
MHGHIHEH_01765 1.8e-273 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHGHIHEH_01766 3.03e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MHGHIHEH_01767 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
MHGHIHEH_01768 8.72e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MHGHIHEH_01769 5.87e-177 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHGHIHEH_01770 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MHGHIHEH_01771 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MHGHIHEH_01772 9.98e-73 - - - - - - - -
MHGHIHEH_01773 8.95e-132 yibE - - S - - - overlaps another CDS with the same product name
MHGHIHEH_01774 7.67e-93 yibE - - S - - - overlaps another CDS with the same product name
MHGHIHEH_01775 3.27e-151 yibF - - S - - - overlaps another CDS with the same product name
MHGHIHEH_01776 7.41e-148 - - - S - - - Calcineurin-like phosphoesterase
MHGHIHEH_01777 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHGHIHEH_01778 2.93e-150 yutD - - S - - - Protein of unknown function (DUF1027)
MHGHIHEH_01779 1.34e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHGHIHEH_01780 2.62e-145 - - - S - - - Protein of unknown function (DUF1461)
MHGHIHEH_01781 8.69e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MHGHIHEH_01782 2.26e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
MHGHIHEH_01783 1.35e-237 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MHGHIHEH_01784 2.99e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHGHIHEH_01785 1.17e-82 yugI - - J ko:K07570 - ko00000 general stress protein
MHGHIHEH_01792 4.32e-105 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MHGHIHEH_01793 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHGHIHEH_01794 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHGHIHEH_01795 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHGHIHEH_01796 1.27e-47 - 3.4.23.43 - - ko:K02236 - ko00000,ko00002,ko01000,ko02044 -
MHGHIHEH_01797 0.0 - - - M - - - domain protein
MHGHIHEH_01798 1.11e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHGHIHEH_01799 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHGHIHEH_01800 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHGHIHEH_01801 2.68e-252 - - - K - - - WYL domain
MHGHIHEH_01802 3.96e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
MHGHIHEH_01803 2.1e-89 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MHGHIHEH_01804 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MHGHIHEH_01805 4.01e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHGHIHEH_01806 1.98e-140 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MHGHIHEH_01807 1.02e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHGHIHEH_01808 7.23e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHGHIHEH_01809 5.26e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHGHIHEH_01810 4.5e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHGHIHEH_01811 6.88e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHGHIHEH_01812 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHGHIHEH_01813 3.55e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MHGHIHEH_01814 5.93e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHGHIHEH_01815 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHGHIHEH_01816 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHGHIHEH_01817 8.67e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHGHIHEH_01818 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHGHIHEH_01819 2.61e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHGHIHEH_01820 1.62e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHGHIHEH_01821 5.74e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHGHIHEH_01822 2.6e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MHGHIHEH_01823 4.07e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MHGHIHEH_01824 2.01e-303 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHGHIHEH_01825 1.29e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHGHIHEH_01826 4.15e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHGHIHEH_01827 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MHGHIHEH_01828 3.11e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHGHIHEH_01829 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHGHIHEH_01830 1.26e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHGHIHEH_01831 5.46e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MHGHIHEH_01832 2.48e-151 - - - - - - - -
MHGHIHEH_01833 1.15e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHGHIHEH_01834 1.92e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHGHIHEH_01835 4.62e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHGHIHEH_01836 6.62e-177 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHGHIHEH_01837 1.2e-42 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MHGHIHEH_01838 2.97e-27 ORF00048 - - - - - - -
MHGHIHEH_01839 2.18e-169 tipA - - K - - - TipAS antibiotic-recognition domain
MHGHIHEH_01840 1.5e-44 - - - - - - - -
MHGHIHEH_01841 1.01e-161 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_01842 2.05e-235 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MHGHIHEH_01843 1.99e-138 - - - K - - - Bacterial regulatory proteins, tetR family
MHGHIHEH_01844 2.98e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHGHIHEH_01845 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MHGHIHEH_01846 6.17e-73 - - - - - - - -
MHGHIHEH_01847 3.73e-126 - - - - - - - -
MHGHIHEH_01848 1.48e-40 - - - S - - - Protein of unknown function (DUF2785)
MHGHIHEH_01849 2.47e-169 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_01850 3.49e-172 XK27_06945 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHGHIHEH_01851 2.27e-174 XK27_06950 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHGHIHEH_01852 2.8e-190 ssuC - - U ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHGHIHEH_01853 1.17e-154 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_01854 2.71e-299 - - - I - - - Acyltransferase family
MHGHIHEH_01855 0.0 - 6.2.1.48 - IQ ko:K02182 - ko00000,ko01000 AMP-binding enzyme C-terminal domain
MHGHIHEH_01856 4.18e-103 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
MHGHIHEH_01857 7.07e-100 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
MHGHIHEH_01858 3.27e-187 ptxC - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHGHIHEH_01859 1e-173 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHGHIHEH_01860 6.08e-178 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MHGHIHEH_01861 1.99e-212 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MHGHIHEH_01862 3.3e-284 - - - P - - - Cation transporter/ATPase, N-terminus
MHGHIHEH_01863 1.51e-280 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHGHIHEH_01866 7.54e-90 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHGHIHEH_01867 3.56e-68 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHGHIHEH_01871 1.86e-155 - - - - - - - -
MHGHIHEH_01874 2.1e-27 - - - - - - - -
MHGHIHEH_01875 1.26e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHGHIHEH_01876 0.0 - - - M - - - domain protein
MHGHIHEH_01877 1.17e-100 - - - - - - - -
MHGHIHEH_01878 8.09e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MHGHIHEH_01879 2.83e-152 - - - GM - - - NmrA-like family
MHGHIHEH_01880 6.75e-215 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHGHIHEH_01881 1.57e-299 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MHGHIHEH_01882 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MHGHIHEH_01883 1.12e-128 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHGHIHEH_01884 1.98e-234 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MHGHIHEH_01885 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHGHIHEH_01886 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHGHIHEH_01887 1.39e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHGHIHEH_01888 8.48e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHGHIHEH_01889 1.63e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MHGHIHEH_01890 6.06e-274 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHGHIHEH_01891 2.66e-102 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHGHIHEH_01892 3.87e-135 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MHGHIHEH_01893 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHGHIHEH_01894 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHGHIHEH_01895 1.02e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MHGHIHEH_01896 3.88e-38 - - - - - - - -
MHGHIHEH_01897 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MHGHIHEH_01898 3.36e-61 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MHGHIHEH_01900 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHGHIHEH_01901 1.18e-310 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MHGHIHEH_01902 4.17e-262 yueF - - S - - - AI-2E family transporter
MHGHIHEH_01903 1.88e-96 yjcF - - S - - - Acetyltransferase (GNAT) domain
MHGHIHEH_01904 3.88e-123 - - - - - - - -
MHGHIHEH_01905 1.1e-134 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MHGHIHEH_01906 7.99e-182 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MHGHIHEH_01907 0.0 frvR - - K ko:K02538,ko:K03483,ko:K09685,ko:K18531 - ko00000,ko03000 transcriptional antiterminator
MHGHIHEH_01908 1.52e-81 - - - - - - - -
MHGHIHEH_01909 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHGHIHEH_01910 1.68e-103 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MHGHIHEH_01911 2.48e-171 - - - K ko:K03489 - ko00000,ko03000 UTRA
MHGHIHEH_01912 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHGHIHEH_01913 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGHIHEH_01914 2.36e-111 - - - - - - - -
MHGHIHEH_01915 7.89e-66 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHGHIHEH_01916 6.27e-67 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_01917 0.0 poxL 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHGHIHEH_01918 2.6e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MHGHIHEH_01919 4.66e-267 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MHGHIHEH_01920 6.69e-264 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MHGHIHEH_01921 7.23e-66 - - - - - - - -
MHGHIHEH_01922 5.75e-206 - - - G - - - Xylose isomerase domain protein TIM barrel
MHGHIHEH_01923 6.06e-132 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
MHGHIHEH_01924 2.25e-201 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 converts alpha-aldose to the beta-anomer
MHGHIHEH_01925 3.11e-271 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MHGHIHEH_01926 4.33e-132 - - - S - - - ECF transporter, substrate-specific component
MHGHIHEH_01928 4e-105 - - - K - - - Acetyltransferase GNAT Family
MHGHIHEH_01929 1.65e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MHGHIHEH_01930 3.35e-167 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_01931 4.02e-188 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHGHIHEH_01932 4.1e-197 XK27_08835 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_01933 2.77e-94 - - - - - - - -
MHGHIHEH_01934 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MHGHIHEH_01935 6.59e-276 - - - V - - - Beta-lactamase
MHGHIHEH_01936 2.51e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHGHIHEH_01937 1.57e-280 - - - V - - - Beta-lactamase
MHGHIHEH_01938 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHGHIHEH_01939 1.62e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MHGHIHEH_01940 8.7e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHGHIHEH_01941 1.13e-177 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHGHIHEH_01942 0.0 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
MHGHIHEH_01945 2.96e-203 - - - S - - - Calcineurin-like phosphoesterase
MHGHIHEH_01946 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MHGHIHEH_01947 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_01948 1.71e-87 - - - - - - - -
MHGHIHEH_01949 6.13e-100 - - - S - - - function, without similarity to other proteins
MHGHIHEH_01950 0.0 - - - G - - - MFS/sugar transport protein
MHGHIHEH_01951 3.08e-291 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
MHGHIHEH_01952 8.15e-77 - - - - - - - -
MHGHIHEH_01953 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MHGHIHEH_01954 6.28e-25 - - - S - - - Virus attachment protein p12 family
MHGHIHEH_01955 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MHGHIHEH_01956 4.14e-91 - - - P ko:K04758 - ko00000,ko02000 FeoA
MHGHIHEH_01957 4.77e-167 - - - E - - - lipolytic protein G-D-S-L family
MHGHIHEH_01960 2.51e-150 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MHGHIHEH_01961 3.31e-78 - - - S - - - MucBP domain
MHGHIHEH_01962 9.73e-109 - - - - - - - -
MHGHIHEH_01963 2.57e-109 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHGHIHEH_01964 2.19e-152 - - - K - - - Helix-turn-helix domain, rpiR family
MHGHIHEH_01965 1e-174 - - - K - - - M protein trans-acting positive regulator
MHGHIHEH_01966 6.42e-112 - - - - - - - -
MHGHIHEH_01967 1.35e-143 - - - - - - - -
MHGHIHEH_01969 0.0 - - - - - - - -
MHGHIHEH_01971 0.0 hylB 4.2.2.1 PL8 N ko:K01727 - ko00000,ko01000 Polysaccharide lyase family 8, N terminal alpha-helical domain
MHGHIHEH_01972 0.0 - 2.7.1.199, 2.7.1.208 - G ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MHGHIHEH_01973 0.0 - 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MHGHIHEH_01974 1.71e-156 kinE - - T - - - Histidine kinase
MHGHIHEH_01975 1.62e-149 - - - S ko:K03975 - ko00000 SNARE-like domain protein
MHGHIHEH_01976 1.73e-148 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
MHGHIHEH_01977 2.36e-219 ykoT - - M - - - Glycosyl transferase family 2
MHGHIHEH_01978 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHGHIHEH_01979 4.14e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHGHIHEH_01980 2.41e-149 alkD - - L - - - DNA alkylation repair enzyme
MHGHIHEH_01982 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHGHIHEH_01983 9.56e-208 - - - J - - - Methyltransferase domain
MHGHIHEH_01984 5.43e-185 rdrB - - K ko:K02444,ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MHGHIHEH_01985 3.66e-108 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_01986 1.52e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_01987 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHGHIHEH_01989 1.51e-175 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
MHGHIHEH_01990 1.1e-172 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MHGHIHEH_01991 3.63e-306 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGHIHEH_01992 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
MHGHIHEH_01993 5.65e-314 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
MHGHIHEH_01994 5.67e-200 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MHGHIHEH_01995 0.0 bgl 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHGHIHEH_01996 2.1e-65 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_01997 8.88e-63 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHGHIHEH_01998 4.71e-191 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_01999 2.3e-167 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_02000 1.16e-214 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_02001 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
MHGHIHEH_02002 2.22e-174 - - - K - - - UTRA domain
MHGHIHEH_02003 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHGHIHEH_02004 2.36e-167 rpl - - K - - - Helix-turn-helix domain, rpiR family
MHGHIHEH_02005 1.09e-222 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MHGHIHEH_02006 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHGHIHEH_02007 5.24e-116 - - - - - - - -
MHGHIHEH_02008 1.27e-153 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MHGHIHEH_02009 1.97e-235 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHGHIHEH_02010 4.96e-290 - - - EK - - - Aminotransferase, class I
MHGHIHEH_02011 4.39e-213 - - - K - - - LysR substrate binding domain
MHGHIHEH_02012 1.09e-114 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHGHIHEH_02013 7.22e-197 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MHGHIHEH_02014 6.36e-161 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
MHGHIHEH_02015 3.43e-138 - - - S - - - Protein of unknown function (DUF1275)
MHGHIHEH_02016 1.99e-16 - - - - - - - -
MHGHIHEH_02017 4.04e-79 - - - - - - - -
MHGHIHEH_02018 5.86e-187 - - - S - - - hydrolase
MHGHIHEH_02019 6.25e-246 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MHGHIHEH_02020 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
MHGHIHEH_02021 6.41e-92 - - - K - - - MarR family
MHGHIHEH_02022 7.3e-149 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHGHIHEH_02024 1.15e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHGHIHEH_02025 1.32e-221 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 Voltage-dependent anion channel
MHGHIHEH_02026 1.98e-193 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MHGHIHEH_02027 0.0 - - - L - - - DNA helicase
MHGHIHEH_02029 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHGHIHEH_02030 1.7e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHGHIHEH_02031 1.23e-142 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHGHIHEH_02032 1.18e-250 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHGHIHEH_02033 3.84e-235 - - - - - - - -
MHGHIHEH_02034 1.7e-203 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_02035 4.97e-81 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MHGHIHEH_02036 1.1e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHGHIHEH_02037 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MHGHIHEH_02038 3.12e-68 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_02039 5.99e-243 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHGHIHEH_02040 8.44e-130 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MHGHIHEH_02041 3.82e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MHGHIHEH_02042 2.95e-96 - - - - - - - -
MHGHIHEH_02043 2.42e-117 - - - T - - - ECF transporter, substrate-specific component
MHGHIHEH_02044 6.13e-232 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MHGHIHEH_02045 3.86e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MHGHIHEH_02046 1.74e-191 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHGHIHEH_02047 7.92e-76 yabA - - L - - - Involved in initiation control of chromosome replication
MHGHIHEH_02048 2.28e-223 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHGHIHEH_02049 1.14e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
MHGHIHEH_02050 7.2e-151 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHGHIHEH_02051 2.95e-46 - - - S - - - Protein of unknown function (DUF2508)
MHGHIHEH_02052 1.26e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHGHIHEH_02053 7e-49 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHGHIHEH_02054 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHGHIHEH_02055 1.26e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHGHIHEH_02056 9.05e-67 - - - - - - - -
MHGHIHEH_02057 3.34e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MHGHIHEH_02058 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHGHIHEH_02059 1.15e-59 - - - - - - - -
MHGHIHEH_02060 8.64e-225 ccpB - - K - - - lacI family
MHGHIHEH_02061 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHGHIHEH_02062 1.98e-204 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHGHIHEH_02063 1.37e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHGHIHEH_02064 7.23e-108 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHGHIHEH_02065 1.92e-283 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MHGHIHEH_02066 6.03e-200 - - - K - - - acetyltransferase
MHGHIHEH_02067 4.02e-86 - - - - - - - -
MHGHIHEH_02068 1.19e-277 yceI - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MHGHIHEH_02069 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHGHIHEH_02070 1.89e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHGHIHEH_02071 6.87e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHGHIHEH_02072 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MHGHIHEH_02073 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
MHGHIHEH_02074 6.01e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MHGHIHEH_02075 5.08e-119 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
MHGHIHEH_02076 6.47e-124 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
MHGHIHEH_02077 4.31e-83 - - - S - - - Domain of unknown function (DUF4430)
MHGHIHEH_02078 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
MHGHIHEH_02079 3.77e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MHGHIHEH_02080 1.16e-203 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHGHIHEH_02081 2.29e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MHGHIHEH_02082 2.09e-30 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHGHIHEH_02083 4.58e-220 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MHGHIHEH_02084 2.44e-216 menA 2.5.1.74 - M ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
MHGHIHEH_02085 2.2e-252 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHGHIHEH_02086 6.86e-187 cad - - S ko:K20379 ko02024,map02024 ko00000,ko00001 FMN_bind
MHGHIHEH_02087 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHGHIHEH_02088 2.76e-104 - - - S - - - NusG domain II
MHGHIHEH_02089 1.03e-127 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
MHGHIHEH_02090 1.05e-228 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHGHIHEH_02092 9.38e-158 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 Rossmann-like domain
MHGHIHEH_02093 6.03e-248 XK27_00915 - - C - - - Luciferase-like monooxygenase
MHGHIHEH_02094 1.65e-153 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_02095 2.14e-219 - - - - - - - -
MHGHIHEH_02096 4.49e-186 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHGHIHEH_02098 8.13e-104 ccl - - S - - - QueT transporter
MHGHIHEH_02099 2.57e-160 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHGHIHEH_02100 8.55e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
MHGHIHEH_02101 1.32e-63 - - - K - - - sequence-specific DNA binding
MHGHIHEH_02102 6.17e-151 gpm5 - - G - - - Phosphoglycerate mutase family
MHGHIHEH_02103 2.59e-229 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHGHIHEH_02104 2.03e-250 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHGHIHEH_02105 3.01e-227 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGHIHEH_02106 1.4e-208 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGHIHEH_02107 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHGHIHEH_02108 0.0 - - - EGP - - - Major Facilitator Superfamily
MHGHIHEH_02109 4.1e-130 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHGHIHEH_02110 1.34e-170 lutC - - S ko:K00782 - ko00000 LUD domain
MHGHIHEH_02111 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
MHGHIHEH_02112 1.7e-190 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
MHGHIHEH_02113 2.39e-109 - - - - - - - -
MHGHIHEH_02114 1.09e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
MHGHIHEH_02115 4.92e-266 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MHGHIHEH_02116 1.62e-90 - - - S - - - Domain of unknown function (DUF3284)
MHGHIHEH_02118 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGHIHEH_02119 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MHGHIHEH_02120 2.13e-173 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MHGHIHEH_02121 5.88e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
MHGHIHEH_02122 0.0 - 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Helix-hairpin-helix containing domain
MHGHIHEH_02123 4.36e-103 - - - - - - - -
MHGHIHEH_02124 9.27e-77 - - - S - - - WxL domain surface cell wall-binding
MHGHIHEH_02125 6.84e-186 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MHGHIHEH_02126 1.52e-130 hyuA - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
MHGHIHEH_02127 6.74e-176 - - - - - - - -
MHGHIHEH_02128 0.0 - - - S - - - Protein of unknown function (DUF1524)
MHGHIHEH_02129 1.21e-75 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MHGHIHEH_02130 4.1e-222 - - - L - - - Belongs to the 'phage' integrase family
MHGHIHEH_02131 3.63e-82 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MHGHIHEH_02132 1.11e-251 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MHGHIHEH_02133 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MHGHIHEH_02134 3.16e-98 - - - - - - - -
MHGHIHEH_02135 2.02e-270 - - - - - - - -
MHGHIHEH_02136 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_02137 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHGHIHEH_02138 1.75e-231 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MHGHIHEH_02139 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MHGHIHEH_02140 7e-210 - - - GM - - - NmrA-like family
MHGHIHEH_02141 4.81e-298 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MHGHIHEH_02142 8.04e-183 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MHGHIHEH_02143 1.02e-192 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHGHIHEH_02144 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MHGHIHEH_02145 3.23e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHGHIHEH_02146 2.14e-88 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHGHIHEH_02147 3.31e-282 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHGHIHEH_02148 8.26e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MHGHIHEH_02149 2.82e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MHGHIHEH_02150 9.2e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MHGHIHEH_02151 1.38e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHGHIHEH_02152 3.96e-226 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHGHIHEH_02153 2.44e-99 - - - K - - - Winged helix DNA-binding domain
MHGHIHEH_02154 6.79e-95 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MHGHIHEH_02155 1.47e-245 - - - E - - - Alpha/beta hydrolase family
MHGHIHEH_02156 1.86e-288 - - - C - - - Iron-containing alcohol dehydrogenase
MHGHIHEH_02157 1.81e-292 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHGHIHEH_02158 0.0 - - - K - - - Mga helix-turn-helix domain
MHGHIHEH_02159 0.0 - - - K - - - Mga helix-turn-helix domain
MHGHIHEH_02160 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MHGHIHEH_02162 2.4e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MHGHIHEH_02163 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MHGHIHEH_02164 4.81e-127 - - - - - - - -
MHGHIHEH_02165 2.94e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHGHIHEH_02166 3.08e-242 - - - S - - - Protein of unknown function C-terminal (DUF3324)
MHGHIHEH_02167 8.02e-114 - - - - - - - -
MHGHIHEH_02168 1.43e-25 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHGHIHEH_02169 6.98e-149 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MHGHIHEH_02170 2.25e-201 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHGHIHEH_02171 4.2e-200 - - - I - - - alpha/beta hydrolase fold
MHGHIHEH_02172 4.96e-35 - - - - - - - -
MHGHIHEH_02173 7.43e-97 - - - - - - - -
MHGHIHEH_02174 8.1e-199 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MHGHIHEH_02175 4.14e-163 citR - - K - - - FCD
MHGHIHEH_02176 0.0 oadA 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Conserved carboxylase domain
MHGHIHEH_02177 4.61e-120 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MHGHIHEH_02178 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MHGHIHEH_02179 7.46e-201 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MHGHIHEH_02180 3.41e-65 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MHGHIHEH_02181 2.88e-226 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MHGHIHEH_02182 3.26e-07 - - - - - - - -
MHGHIHEH_02183 1.13e-250 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
MHGHIHEH_02184 1.76e-59 oadG - - I - - - Biotin-requiring enzyme
MHGHIHEH_02185 2.14e-69 - - - - - - - -
MHGHIHEH_02186 4.1e-307 citM - - C ko:K03300 - ko00000 Citrate transporter
MHGHIHEH_02187 3.61e-55 - - - - - - - -
MHGHIHEH_02188 4.44e-134 kptA - - J ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MHGHIHEH_02189 2.7e-57 - - - K - - - GNAT family
MHGHIHEH_02190 4.49e-136 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MHGHIHEH_02191 1.13e-75 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MHGHIHEH_02192 1.49e-189 ORF00048 - - - - - - -
MHGHIHEH_02193 2.58e-176 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MHGHIHEH_02194 3.34e-215 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_02195 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MHGHIHEH_02196 1.63e-146 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MHGHIHEH_02197 0.0 - - - EGP - - - Major Facilitator
MHGHIHEH_02198 1.65e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
MHGHIHEH_02199 4.41e-201 - - - K - - - Helix-turn-helix XRE-family like proteins
MHGHIHEH_02200 1.85e-206 - - - S - - - Alpha beta hydrolase
MHGHIHEH_02201 2.73e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MHGHIHEH_02202 1.6e-161 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_02203 1.32e-15 - - - - - - - -
MHGHIHEH_02204 3.8e-176 - - - - - - - -
MHGHIHEH_02205 1.5e-112 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_02206 1.01e-122 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHGHIHEH_02207 7.79e-203 - - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
MHGHIHEH_02208 2.29e-253 - - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
MHGHIHEH_02210 3.78e-223 - - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGHIHEH_02211 5.97e-215 - - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHGHIHEH_02212 0.0 - - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MHGHIHEH_02213 1.98e-163 - - - S - - - DJ-1/PfpI family
MHGHIHEH_02214 2.12e-70 - - - K - - - Transcriptional
MHGHIHEH_02215 8.8e-48 - - - - - - - -
MHGHIHEH_02216 0.0 - - - V - - - ABC transporter transmembrane region
MHGHIHEH_02217 0.0 - - - V ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter transmembrane region
MHGHIHEH_02219 3.24e-89 - - - S - - - Iron-sulphur cluster biosynthesis
MHGHIHEH_02220 3.05e-19 - 2.7.1.39 - S ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Phosphotransferase enzyme family
MHGHIHEH_02221 4.56e-298 - - - M - - - LysM domain
MHGHIHEH_02222 5.19e-67 - - - M - - - LysM domain
MHGHIHEH_02223 1.6e-171 zmp3 - - O - - - Zinc-dependent metalloprotease
MHGHIHEH_02224 4.37e-22 - - - - - - - -
MHGHIHEH_02225 5.04e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MHGHIHEH_02226 2.21e-181 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHGHIHEH_02227 4.83e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHGHIHEH_02228 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHGHIHEH_02229 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MHGHIHEH_02230 2.65e-139 - - - - - - - -
MHGHIHEH_02232 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHGHIHEH_02233 4.9e-239 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MHGHIHEH_02234 1.01e-150 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MHGHIHEH_02235 1.73e-182 - - - K - - - SIS domain
MHGHIHEH_02236 2.26e-146 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
MHGHIHEH_02237 1.37e-226 - - - S - - - Membrane
MHGHIHEH_02238 5.31e-82 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
MHGHIHEH_02239 1.17e-286 inlJ - - M - - - MucBP domain
MHGHIHEH_02240 6.64e-243 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MHGHIHEH_02241 3.13e-97 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHGHIHEH_02242 1.25e-135 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_02243 1.45e-148 - - - K - - - sequence-specific DNA binding
MHGHIHEH_02244 5.49e-261 yacL - - S - - - domain protein
MHGHIHEH_02245 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHGHIHEH_02246 4.85e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTPase
MHGHIHEH_02247 1.22e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MHGHIHEH_02248 5.93e-93 - - - S - - - Protein of unknown function (DUF805)
MHGHIHEH_02249 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MHGHIHEH_02250 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MHGHIHEH_02251 1.09e-253 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHGHIHEH_02252 2.48e-275 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHGHIHEH_02253 5.79e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_02254 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MHGHIHEH_02255 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
MHGHIHEH_02256 8.84e-120 ccpN - - K - - - Domain in cystathionine beta-synthase and other proteins.
MHGHIHEH_02257 2.41e-158 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHGHIHEH_02258 9.51e-263 - - - S - - - Bacterial low temperature requirement A protein (LtrA)
MHGHIHEH_02259 5.25e-61 - - - - - - - -
MHGHIHEH_02260 1.64e-262 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MHGHIHEH_02261 1.59e-28 yhjA - - K - - - CsbD-like
MHGHIHEH_02263 1.5e-44 - - - - - - - -
MHGHIHEH_02264 5.02e-52 - - - - - - - -
MHGHIHEH_02265 8.53e-287 - - - EGP - - - Transmembrane secretion effector
MHGHIHEH_02266 2.21e-277 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHGHIHEH_02267 6.34e-190 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHGHIHEH_02269 3.64e-55 - - - - - - - -
MHGHIHEH_02270 9.34e-294 - - - S - - - Membrane
MHGHIHEH_02271 1.05e-187 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MHGHIHEH_02272 0.0 - - - M - - - Cna protein B-type domain
MHGHIHEH_02273 1.01e-307 - - - - - - - -
MHGHIHEH_02274 0.0 - - - M - - - domain protein
MHGHIHEH_02276 1.56e-37 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_02277 2.85e-56 yleF - - K - - - Helix-turn-helix domain, rpiR family
MHGHIHEH_02278 8.19e-119 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHGHIHEH_02279 6.83e-98 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MHGHIHEH_02280 2e-278 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_02281 1.88e-139 - - - S - - - Putative esterase
MHGHIHEH_02283 1.51e-173 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MHGHIHEH_02285 2.06e-57 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MHGHIHEH_02286 6.94e-92 xylR - - GK - - - ROK family
MHGHIHEH_02287 2.11e-38 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHGHIHEH_02288 4.11e-83 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHGHIHEH_02289 1.46e-148 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHGHIHEH_02290 1.27e-144 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHGHIHEH_02291 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
MHGHIHEH_02293 3.62e-56 - - - L - - - PFAM transposase, IS4 family protein
MHGHIHEH_02295 1.87e-31 - - - K - - - Cro/C1-type HTH DNA-binding domain
MHGHIHEH_02297 3.78e-41 XK27_08510 - - L - - - Type III restriction protein res subunit
MHGHIHEH_02298 2.35e-212 XK27_08510 - - L - - - Type III restriction protein res subunit
MHGHIHEH_02299 0.0 - - - L - - - Transposase DDE domain
MHGHIHEH_02300 0.0 sthIR 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
MHGHIHEH_02301 2.08e-263 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
MHGHIHEH_02302 1.84e-34 - - - - - - - -
MHGHIHEH_02303 2.83e-244 - - - L - - - Psort location Cytoplasmic, score
MHGHIHEH_02304 7.27e-42 - - - - - - - -
MHGHIHEH_02305 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHGHIHEH_02306 1.71e-86 - - - - - - - -
MHGHIHEH_02307 1.56e-194 - - - - - - - -
MHGHIHEH_02308 1.22e-79 - - - - - - - -
MHGHIHEH_02309 0.0 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
MHGHIHEH_02310 1.82e-102 - - - - - - - -
MHGHIHEH_02311 5.77e-123 - - - - - - - -
MHGHIHEH_02312 2.59e-277 - - - M - - - CHAP domain
MHGHIHEH_02313 0.0 - - - S - - - WXG100 protein secretion system (Wss), protein YukC
MHGHIHEH_02314 0.0 - - - U - - - type IV secretory pathway VirB4
MHGHIHEH_02315 4.48e-152 - - - - - - - -
MHGHIHEH_02316 8.94e-70 - - - - - - - -
MHGHIHEH_02317 6.31e-68 - - - S - - - Cag pathogenicity island, type IV secretory system
MHGHIHEH_02318 3.99e-134 - - - - - - - -
MHGHIHEH_02319 7.08e-68 - - - - - - - -
MHGHIHEH_02320 0.0 traA - - L - - - MobA MobL family protein
MHGHIHEH_02321 3.41e-37 - - - - - - - -
MHGHIHEH_02322 2.51e-55 - - - - - - - -
MHGHIHEH_02323 3.89e-112 - - - - - - - -
MHGHIHEH_02324 6.94e-59 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
MHGHIHEH_02325 2.44e-36 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MHGHIHEH_02327 2.66e-112 repA - - S - - - Replication initiator protein A
MHGHIHEH_02328 6.29e-126 - - - D - - - Cellulose biosynthesis protein BcsQ
MHGHIHEH_02330 4.82e-08 yokH - - G - - - SMI1 / KNR4 family
MHGHIHEH_02331 5.44e-256 ypjH - - C ko:K08317 - ko00000,ko01000 dehydrogenase
MHGHIHEH_02332 1.53e-288 amd - - E - - - Peptidase family M20/M25/M40
MHGHIHEH_02333 1.48e-104 - - - S - - - Threonine/Serine exporter, ThrE
MHGHIHEH_02334 3.8e-175 labL - - S - - - Putative threonine/serine exporter
MHGHIHEH_02336 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHGHIHEH_02337 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHGHIHEH_02339 1.42e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
MHGHIHEH_02340 4.53e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHGHIHEH_02341 2.99e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHGHIHEH_02342 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MHGHIHEH_02343 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHGHIHEH_02344 1.02e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHGHIHEH_02346 4.07e-43 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MHGHIHEH_02347 9.09e-260 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHGHIHEH_02348 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHGHIHEH_02349 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHGHIHEH_02350 5.22e-163 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHGHIHEH_02351 5.2e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHGHIHEH_02352 1.36e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MHGHIHEH_02353 1.54e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHGHIHEH_02354 3.26e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHGHIHEH_02355 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit I
MHGHIHEH_02356 1.74e-223 - - - C - - - Cytochrome bd terminal oxidase subunit II
MHGHIHEH_02357 1.07e-35 - - - - - - - -
MHGHIHEH_02358 9.41e-136 - - - S - - - Protein of unknown function (DUF1211)
MHGHIHEH_02361 1.94e-181 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHGHIHEH_02365 4.92e-201 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
MHGHIHEH_02366 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHGHIHEH_02367 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_02368 1.09e-125 - - - K - - - transcriptional regulator
MHGHIHEH_02369 4.35e-197 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
MHGHIHEH_02370 4.92e-65 - - - - - - - -
MHGHIHEH_02373 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
MHGHIHEH_02374 1.38e-158 - - - S ko:K07090 - ko00000 membrane transporter protein
MHGHIHEH_02375 2.33e-131 - - - S - - - Protein of unknown function (DUF1211)
MHGHIHEH_02376 4.74e-211 - - - P - - - CorA-like Mg2+ transporter protein
MHGHIHEH_02377 3.84e-145 - - - K - - - Bacterial regulatory proteins, tetR family
MHGHIHEH_02382 4.77e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHGHIHEH_02383 1.85e-66 - - - - - - - -
MHGHIHEH_02384 4.01e-262 - - - S - - - Protein of unknown function (DUF2974)
MHGHIHEH_02385 2.81e-99 - - - K - - - Helix-turn-helix XRE-family like proteins
MHGHIHEH_02386 2.05e-72 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MHGHIHEH_02387 6.77e-81 - - - - - - - -
MHGHIHEH_02388 1.22e-175 - - - - - - - -
MHGHIHEH_02389 6.69e-61 - - - S - - - Enterocin A Immunity
MHGHIHEH_02390 2.22e-60 - - - S - - - Enterocin A Immunity
MHGHIHEH_02391 4.94e-59 spiA - - K - - - TRANSCRIPTIONal
MHGHIHEH_02392 0.0 - - - S - - - Putative threonine/serine exporter
MHGHIHEH_02394 5.75e-72 - - - - - - - -
MHGHIHEH_02395 6.57e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MHGHIHEH_02396 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MHGHIHEH_02398 2.1e-173 - 2.7.13.3 - T ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
MHGHIHEH_02399 7.99e-184 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHGHIHEH_02401 1.62e-12 - - - - - - - -
MHGHIHEH_02405 9.93e-182 - - - S - - - CAAX protease self-immunity
MHGHIHEH_02406 2.29e-74 - - - - - - - -
MHGHIHEH_02408 1.18e-72 - - - S - - - Enterocin A Immunity
MHGHIHEH_02409 7.86e-138 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHGHIHEH_02413 8.37e-231 ydhF - - S - - - Aldo keto reductase
MHGHIHEH_02414 3.51e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGHIHEH_02415 4.77e-270 yqiG - - C - - - Oxidoreductase
MHGHIHEH_02416 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHGHIHEH_02417 2.2e-173 - - - - - - - -
MHGHIHEH_02418 5.81e-22 - - - - - - - -
MHGHIHEH_02419 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHGHIHEH_02420 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MHGHIHEH_02421 1.14e-72 - - - - - - - -
MHGHIHEH_02422 5.26e-293 - - - EGP - - - Major Facilitator Superfamily
MHGHIHEH_02423 0.0 sufI - - Q - - - Multicopper oxidase
MHGHIHEH_02424 1.53e-35 - - - - - - - -
MHGHIHEH_02425 2.22e-144 - - - P - - - Cation efflux family
MHGHIHEH_02426 1.23e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MHGHIHEH_02427 6.58e-226 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHGHIHEH_02428 5.89e-185 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MHGHIHEH_02429 3.38e-170 - 3.6.3.35 - P ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHGHIHEH_02430 0.0 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family
MHGHIHEH_02431 6.85e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHGHIHEH_02432 7.06e-138 - - - K - - - Bacterial regulatory proteins, tetR family
MHGHIHEH_02433 0.0 - - - EGP - - - Major Facilitator
MHGHIHEH_02434 1.59e-266 - - - - - - - -
MHGHIHEH_02435 4.15e-234 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHGHIHEH_02436 8.57e-175 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MHGHIHEH_02437 2.62e-132 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MHGHIHEH_02438 3.37e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHGHIHEH_02439 1.38e-182 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHGHIHEH_02440 1.23e-149 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
MHGHIHEH_02441 2.73e-127 dpsB - - P - - - Belongs to the Dps family
MHGHIHEH_02442 3.61e-46 copZ - - P - - - Heavy-metal-associated domain
MHGHIHEH_02443 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MHGHIHEH_02445 0.000666 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHGHIHEH_02446 1.72e-285 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_02447 2.28e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHGHIHEH_02448 3.55e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHGHIHEH_02449 3.93e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHGHIHEH_02451 2.34e-140 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MHGHIHEH_02452 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MHGHIHEH_02453 3.19e-66 - - - K - - - TRANSCRIPTIONal
MHGHIHEH_02454 1.8e-305 - - - EGP - - - Major Facilitator
MHGHIHEH_02455 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MHGHIHEH_02456 1.13e-208 - - - K - - - Transcriptional activator, Rgg GadR MutR family
MHGHIHEH_02457 2.84e-73 ps105 - - - - - - -
MHGHIHEH_02459 9.03e-162 kdgR - - K - - - FCD domain
MHGHIHEH_02460 6.9e-150 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MHGHIHEH_02461 4.53e-185 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHGHIHEH_02463 4.31e-65 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MHGHIHEH_02464 1.08e-151 azlC - - E - - - branched-chain amino acid
MHGHIHEH_02465 1.23e-97 - - - - - - - -
MHGHIHEH_02466 1.09e-82 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
MHGHIHEH_02467 3.26e-42 - - - - - - - -
MHGHIHEH_02468 8.78e-107 - - - - - - - -
MHGHIHEH_02469 6.62e-143 - - - S - - - Membrane
MHGHIHEH_02470 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHGHIHEH_02471 7.5e-53 - - - K - - - Helix-turn-helix XRE-family like proteins
MHGHIHEH_02472 4.78e-164 XK27_12140 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_02473 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
MHGHIHEH_02474 9.02e-163 - - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MHGHIHEH_02475 7.26e-253 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHGHIHEH_02476 4.81e-181 - - - V - - - ATPases associated with a variety of cellular activities
MHGHIHEH_02477 6.98e-265 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHGHIHEH_02478 3.41e-119 - - - - - - - -
MHGHIHEH_02479 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHGHIHEH_02480 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHGHIHEH_02481 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MHGHIHEH_02482 0.0 ycaM - - E - - - amino acid
MHGHIHEH_02483 1.66e-117 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MHGHIHEH_02484 7.85e-210 - - - K - - - Transcriptional regulator, LysR family
MHGHIHEH_02485 4.66e-206 - - - G - - - Xylose isomerase-like TIM barrel
MHGHIHEH_02486 1.26e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHGHIHEH_02487 1.78e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHGHIHEH_02488 2.58e-274 - - - EGP - - - Major Facilitator Superfamily
MHGHIHEH_02489 2.35e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHGHIHEH_02490 2.74e-206 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MHGHIHEH_02491 2.2e-222 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHGHIHEH_02492 1.52e-24 - - - - - - - -
MHGHIHEH_02494 9.15e-285 int3 - - L - - - Belongs to the 'phage' integrase family
MHGHIHEH_02499 4e-172 - - - - - - - -
MHGHIHEH_02500 6.34e-194 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
MHGHIHEH_02501 3.6e-122 M1-431 - - S - - - Protein of unknown function (DUF1706)
MHGHIHEH_02504 1.77e-83 - - - - - - - -
MHGHIHEH_02505 2.62e-283 yagE - - E - - - Amino acid permease
MHGHIHEH_02506 4.56e-215 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MHGHIHEH_02507 1.37e-285 - - - G - - - phosphotransferase system
MHGHIHEH_02508 9.26e-52 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHGHIHEH_02509 6.71e-150 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHGHIHEH_02511 1.87e-217 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHGHIHEH_02512 2.32e-233 - - - D ko:K06889 - ko00000 Alpha beta
MHGHIHEH_02513 6.18e-238 lipA - - I - - - Carboxylesterase family
MHGHIHEH_02514 1.68e-275 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MHGHIHEH_02515 9.2e-101 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGHIHEH_02516 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
MHGHIHEH_02517 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHGHIHEH_02518 2.05e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHGHIHEH_02519 3.86e-192 - - - S - - - haloacid dehalogenase-like hydrolase
MHGHIHEH_02520 5.93e-59 - - - - - - - -
MHGHIHEH_02521 6.72e-19 - - - - - - - -
MHGHIHEH_02522 2.5e-237 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHGHIHEH_02523 2.9e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_02524 3.59e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MHGHIHEH_02525 0.0 - - - M - - - Leucine rich repeats (6 copies)
MHGHIHEH_02526 1.63e-244 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHGHIHEH_02527 2.68e-248 arbF1 - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_02528 5.85e-58 - - - K ko:K03480,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MHGHIHEH_02529 9.52e-240 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MHGHIHEH_02530 0.000324 - - - S - - - CsbD-like
MHGHIHEH_02532 4.73e-205 - - - - - - - -
MHGHIHEH_02533 3.44e-64 - - - - - - - -
MHGHIHEH_02534 8.29e-74 - - - - - - - -
MHGHIHEH_02535 2.11e-69 - - - L ko:K07483 - ko00000 4.5 Transposon and IS
MHGHIHEH_02536 2.5e-174 - - - L - - - Helix-turn-helix domain
MHGHIHEH_02537 1e-214 - - - L ko:K07497 - ko00000 hmm pf00665
MHGHIHEH_02538 1.6e-199 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
MHGHIHEH_02542 6.78e-42 - - - - - - - -
MHGHIHEH_02543 2.75e-257 - - - - - - - -
MHGHIHEH_02544 1.44e-298 - - - M - - - Domain of unknown function (DUF5011)
MHGHIHEH_02547 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
MHGHIHEH_02548 0.0 - - - S - - - domain, Protein
MHGHIHEH_02550 9.18e-137 - - - - - - - -
MHGHIHEH_02551 0.0 - - - S - - - COG0433 Predicted ATPase
MHGHIHEH_02552 1.77e-237 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 cysteine-type peptidase activity
MHGHIHEH_02559 4.89e-283 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
MHGHIHEH_02561 0.0 - - - L - - - Protein of unknown function (DUF3991)
MHGHIHEH_02562 1.18e-216 - - - L - - - Protein of unknown function (DUF3991)
MHGHIHEH_02563 1.97e-84 - - - - - - - -
MHGHIHEH_02564 2.45e-23 - - - - - - - -
MHGHIHEH_02565 1.03e-100 - - - - - - - -
MHGHIHEH_02567 9.59e-101 - - - - - - - -
MHGHIHEH_02568 1.49e-198 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MHGHIHEH_02570 1.77e-76 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MHGHIHEH_02572 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MHGHIHEH_02573 1.77e-56 - - - - - - - -
MHGHIHEH_02574 2.56e-10 - - - L - - - Helix-turn-helix domain
MHGHIHEH_02575 7.54e-205 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MHGHIHEH_02576 5.01e-85 is18 - - L - - - Integrase core domain
MHGHIHEH_02577 3.91e-124 - - - S - - - Phospholipase A2
MHGHIHEH_02579 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MHGHIHEH_02580 1.35e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MHGHIHEH_02581 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MHGHIHEH_02582 4.65e-277 - - - - - - - -
MHGHIHEH_02583 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_02584 1.01e-165 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHGHIHEH_02585 4.06e-153 yleF - - K - - - Helix-turn-helix domain, rpiR family
MHGHIHEH_02586 5.32e-117 - - - K - - - Transcriptional regulator C-terminal region
MHGHIHEH_02587 1.19e-143 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_02588 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHGHIHEH_02589 2.01e-214 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
MHGHIHEH_02590 9.64e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHGHIHEH_02591 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MHGHIHEH_02592 5.08e-74 cadC5 - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MHGHIHEH_02593 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
MHGHIHEH_02594 6.67e-204 lysR5 - - K - - - LysR substrate binding domain
MHGHIHEH_02595 1.19e-256 - - - K - - - Helix-turn-helix XRE-family like proteins
MHGHIHEH_02596 7.81e-46 - - - S - - - Phospholipase_D-nuclease N-terminal
MHGHIHEH_02597 2.64e-214 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHGHIHEH_02598 3.78e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHGHIHEH_02599 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MHGHIHEH_02601 2.59e-129 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
MHGHIHEH_02602 0.0 - - - - - - - -
MHGHIHEH_02603 1.83e-182 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
MHGHIHEH_02604 2.41e-118 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MHGHIHEH_02605 3.02e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHGHIHEH_02606 2.2e-176 - - - S - - - Putative threonine/serine exporter
MHGHIHEH_02607 2.51e-98 - - - S - - - Threonine/Serine exporter, ThrE
MHGHIHEH_02608 2.29e-273 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MHGHIHEH_02609 1.04e-191 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MHGHIHEH_02610 1.1e-182 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MHGHIHEH_02611 3.01e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
MHGHIHEH_02612 3.34e-159 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHGHIHEH_02613 7.59e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHGHIHEH_02614 1.12e-303 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGHIHEH_02615 4.1e-152 - - - G - - - Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MHGHIHEH_02616 1.44e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHGHIHEH_02617 3.24e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHGHIHEH_02618 3.14e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MHGHIHEH_02619 3.91e-211 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MHGHIHEH_02622 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MHGHIHEH_02623 2.06e-177 - - - - - - - -
MHGHIHEH_02624 1.14e-153 - - - - - - - -
MHGHIHEH_02625 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MHGHIHEH_02626 1.42e-306 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHGHIHEH_02627 2.22e-110 - - - - - - - -
MHGHIHEH_02628 0.0 strH 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Gram-positive signal peptide protein, YSIRK family
MHGHIHEH_02629 9.12e-249 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHGHIHEH_02630 5.43e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
MHGHIHEH_02631 9.45e-280 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
MHGHIHEH_02632 6.46e-288 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHGHIHEH_02633 0.0 bgaC 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
MHGHIHEH_02634 1.24e-39 - - - - - - - -
MHGHIHEH_02635 1.37e-165 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MHGHIHEH_02636 2.87e-213 yitS - - S - - - Uncharacterised protein, DegV family COG1307
MHGHIHEH_02637 3.04e-84 - - - K - - - Acetyltransferase (GNAT) family
MHGHIHEH_02638 0.0 - - - EGP - - - Major Facilitator
MHGHIHEH_02639 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MHGHIHEH_02640 2.44e-210 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
MHGHIHEH_02641 5.1e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHGHIHEH_02642 9.24e-281 yttB - - EGP - - - Major Facilitator
MHGHIHEH_02643 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHGHIHEH_02644 4.97e-248 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MHGHIHEH_02645 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHGHIHEH_02646 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHGHIHEH_02647 3.61e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHGHIHEH_02648 4.26e-271 camS - - S - - - sex pheromone
MHGHIHEH_02649 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHGHIHEH_02650 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MHGHIHEH_02652 5.65e-46 - - - S - - - Bacterial protein of unknown function (DUF898)
MHGHIHEH_02653 3.51e-180 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
MHGHIHEH_02654 3.59e-266 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHGHIHEH_02656 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MHGHIHEH_02657 8.56e-74 - - - - - - - -
MHGHIHEH_02658 1.53e-88 - - - - - - - -
MHGHIHEH_02659 7.36e-94 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MHGHIHEH_02660 5.2e-20 - - - - - - - -
MHGHIHEH_02661 1.34e-96 - - - S - - - acetyltransferase
MHGHIHEH_02662 0.0 yclK - - T - - - Histidine kinase
MHGHIHEH_02663 3.55e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MHGHIHEH_02664 5.39e-92 - - - S - - - SdpI/YhfL protein family
MHGHIHEH_02665 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHGHIHEH_02666 0.0 bglH - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHGHIHEH_02667 1.23e-191 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHGHIHEH_02668 0.0 - - - S - - - Bacterial membrane protein YfhO
MHGHIHEH_02669 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
MHGHIHEH_02670 1.42e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MHGHIHEH_02671 8.56e-133 - - - - - - - -
MHGHIHEH_02672 8.49e-217 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MHGHIHEH_02674 6.22e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MHGHIHEH_02675 9.32e-107 yvbK - - K - - - GNAT family
MHGHIHEH_02676 2.4e-148 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MHGHIHEH_02677 5.35e-133 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHGHIHEH_02678 6.23e-303 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MHGHIHEH_02679 1.29e-258 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHGHIHEH_02680 9.74e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHGHIHEH_02681 7.65e-136 - - - - - - - -
MHGHIHEH_02682 7.04e-136 - - - - - - - -
MHGHIHEH_02683 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHGHIHEH_02684 3.2e-143 vanZ - - V - - - VanZ like family
MHGHIHEH_02685 4.66e-196 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
MHGHIHEH_02686 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MHGHIHEH_02687 8.89e-290 - - - L - - - Pfam:Integrase_AP2
MHGHIHEH_02688 1.11e-41 - - - - - - - -
MHGHIHEH_02689 1.1e-89 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MHGHIHEH_02690 2.33e-25 - - - - - - - -
MHGHIHEH_02692 2.67e-24 - - - Q - - - methyltransferase
MHGHIHEH_02693 1.01e-23 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
MHGHIHEH_02696 3.15e-66 - - - - - - - -
MHGHIHEH_02697 1.9e-82 - - - K - - - acetyltransferase
MHGHIHEH_02698 3.54e-39 - - - S - - - ASCH
MHGHIHEH_02699 3.4e-11 - - - - - - - -
MHGHIHEH_02700 4.17e-89 - - - V - - - HNH endonuclease
MHGHIHEH_02701 2.38e-79 - - - - - - - -
MHGHIHEH_02702 0.0 - - - S - - - overlaps another CDS with the same product name
MHGHIHEH_02703 8.05e-297 - - - S - - - Phage portal protein
MHGHIHEH_02704 2.39e-164 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
MHGHIHEH_02705 7.56e-285 - - - S - - - Phage capsid family
MHGHIHEH_02707 9.08e-71 - - - - - - - -
MHGHIHEH_02708 3.92e-76 - - - S - - - Phage head-tail joining protein
MHGHIHEH_02709 1.28e-75 - - - - - - - -
MHGHIHEH_02710 1.24e-86 - - - - - - - -
MHGHIHEH_02711 1.24e-147 - - - - - - - -
MHGHIHEH_02712 5.81e-80 - - - - - - - -
MHGHIHEH_02713 0.0 - - - D - - - Phage tail tape measure protein
MHGHIHEH_02714 1.69e-162 - - - S - - - phage tail
MHGHIHEH_02715 0.0 - - - LM - - - gp58-like protein
MHGHIHEH_02716 1.69e-93 - - - - - - - -
MHGHIHEH_02717 2.49e-48 - - - - - - - -
MHGHIHEH_02718 3.36e-61 - - - - - - - -
MHGHIHEH_02719 7.01e-67 hol - - S - - - Bacteriophage holin
MHGHIHEH_02721 3.78e-251 - - - M - - - Bacteriophage peptidoglycan hydrolase
MHGHIHEH_02722 1.63e-176 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MHGHIHEH_02723 9.39e-80 - - - S - - - Protein of unknown function (DUF1093)
MHGHIHEH_02724 1.9e-79 - - - S - - - Domain of unknown function (DUF4828)
MHGHIHEH_02725 2.21e-226 mocA - - S - - - Oxidoreductase
MHGHIHEH_02726 4.41e-289 yfmL - - L - - - DEAD DEAH box helicase
MHGHIHEH_02727 7.9e-74 chbA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
MHGHIHEH_02728 4.49e-93 - - - S - - - Domain of unknown function (DUF3284)
MHGHIHEH_02730 4.16e-07 - - - - - - - -
MHGHIHEH_02731 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MHGHIHEH_02732 1.41e-306 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
MHGHIHEH_02733 2.96e-144 - - - K - - - Bacterial regulatory proteins, tetR family
MHGHIHEH_02735 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MHGHIHEH_02736 9.73e-230 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MHGHIHEH_02737 1.24e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
MHGHIHEH_02738 1.16e-204 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MHGHIHEH_02739 3.04e-258 - - - M - - - Glycosyltransferase like family 2
MHGHIHEH_02741 1.02e-20 - - - - - - - -
MHGHIHEH_02742 4.45e-253 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MHGHIHEH_02743 4.4e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MHGHIHEH_02744 2.22e-68 - - - KL - - - HELICc2
MHGHIHEH_02746 3.18e-18 - - - - - - - -
MHGHIHEH_02747 1.02e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MHGHIHEH_02749 1.48e-189 - - - EG - - - EamA-like transporter family
MHGHIHEH_02750 1.35e-97 - - - L - - - NUDIX domain
MHGHIHEH_02751 5.73e-82 - - - - - - - -
MHGHIHEH_02752 5.59e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHGHIHEH_02753 2.33e-237 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHGHIHEH_02754 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHGHIHEH_02755 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHGHIHEH_02756 4.4e-116 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHGHIHEH_02757 7.47e-281 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHGHIHEH_02758 6.02e-216 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHGHIHEH_02759 2.21e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHGHIHEH_02761 7.06e-81 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHGHIHEH_02764 1.28e-135 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_02765 8.73e-206 - - - - - - - -
MHGHIHEH_02766 7.33e-272 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-type transport system involved in multi-copper enzyme maturation permease component
MHGHIHEH_02767 1.6e-160 - - - - - - - -
MHGHIHEH_02769 4.07e-150 - - - P ko:K15551 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
MHGHIHEH_02770 4.2e-130 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MHGHIHEH_02772 1.2e-61 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
MHGHIHEH_02773 0.0 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
MHGHIHEH_02774 1.7e-72 - - - S - - - Protein of unknown function (DUF1516)
MHGHIHEH_02775 3.12e-70 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MHGHIHEH_02776 4.54e-204 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 alcohol dehydrogenase
MHGHIHEH_02777 1.85e-110 - - - K - - - Transcriptional regulator
MHGHIHEH_02778 9.97e-59 - - - - - - - -
MHGHIHEH_02779 1.66e-245 ldhD3 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHGHIHEH_02780 3.37e-115 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
MHGHIHEH_02781 2.61e-261 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MHGHIHEH_02782 6.55e-57 - - - - - - - -
MHGHIHEH_02783 2.35e-269 mccF - - V - - - LD-carboxypeptidase
MHGHIHEH_02784 3.7e-234 yveB - - I - - - PAP2 superfamily
MHGHIHEH_02785 2.66e-57 - - - S - - - Protein of unknown function (DUF2089)
MHGHIHEH_02786 5.67e-49 - - - - - - - -
MHGHIHEH_02790 1.98e-91 - - - - - - - -
MHGHIHEH_02791 4.56e-267 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHGHIHEH_02792 0.0 mdr - - EGP - - - Major Facilitator
MHGHIHEH_02793 3.99e-106 - - - K - - - MerR HTH family regulatory protein
MHGHIHEH_02794 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MHGHIHEH_02795 3.74e-155 - - - S - - - Domain of unknown function (DUF4811)
MHGHIHEH_02796 3.66e-155 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MHGHIHEH_02797 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MHGHIHEH_02798 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MHGHIHEH_02799 4.65e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHGHIHEH_02800 9.15e-45 yhcC - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MHGHIHEH_02801 3.37e-183 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHGHIHEH_02802 2.55e-121 - - - F - - - NUDIX domain
MHGHIHEH_02804 3.68e-136 sip - - L - - - Belongs to the 'phage' integrase family
MHGHIHEH_02806 9.62e-06 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MHGHIHEH_02808 1.91e-77 - - - - - - - -
MHGHIHEH_02809 1.67e-21 - - - - - - - -
MHGHIHEH_02810 4.23e-33 - - - - - - - -
MHGHIHEH_02811 5.2e-46 - - - - - - - -
MHGHIHEH_02812 1.1e-32 - - - - - - - -
MHGHIHEH_02813 1.2e-202 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
MHGHIHEH_02814 0.0 - - - S - - - Virulence-associated protein E
MHGHIHEH_02815 9.8e-97 - - - - - - - -
MHGHIHEH_02816 6.36e-103 terS - - L - - - Phage terminase, small subunit
MHGHIHEH_02817 0.0 terL - - S - - - overlaps another CDS with the same product name
MHGHIHEH_02818 6.06e-29 - - - - - - - -
MHGHIHEH_02819 1.02e-279 - - - S - - - Phage portal protein
MHGHIHEH_02820 0.0 - - - S ko:K06904 - ko00000 Phage capsid family
MHGHIHEH_02821 2.28e-63 - - - S - - - Phage gp6-like head-tail connector protein
MHGHIHEH_02822 4.82e-18 - - - S - - - Phage head-tail joining protein
MHGHIHEH_02824 1.4e-35 ytgB - - S - - - Transglycosylase associated protein
MHGHIHEH_02825 2.3e-23 - - - - - - - -
MHGHIHEH_02827 8.23e-62 - - - S - - - Phage gp6-like head-tail connector protein
MHGHIHEH_02828 0.0 - - - S ko:K06904 - ko00000 Phage capsid family
MHGHIHEH_02829 3.03e-278 - - - S - - - Phage portal protein
MHGHIHEH_02830 8.61e-29 - - - - - - - -
MHGHIHEH_02831 0.0 terL - - S - - - overlaps another CDS with the same product name
MHGHIHEH_02832 3.15e-103 terS - - L - - - Phage terminase, small subunit
MHGHIHEH_02833 9.92e-27 - - - S - - - HNH endonuclease
MHGHIHEH_02835 6.31e-68 - - - S - - - Phage head-tail joining protein
MHGHIHEH_02836 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
MHGHIHEH_02837 9.7e-189 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
MHGHIHEH_02838 5.47e-33 - - - - - - - -
MHGHIHEH_02840 1.17e-30 - - - - - - - -
MHGHIHEH_02841 6.39e-25 - - - - - - - -
MHGHIHEH_02842 1.39e-40 - - - - - - - -
MHGHIHEH_02844 3.06e-06 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MHGHIHEH_02845 1.43e-273 sip - - L - - - Belongs to the 'phage' integrase family
MHGHIHEH_02846 8.92e-105 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MHGHIHEH_02847 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHGHIHEH_02848 1.52e-57 ykuJ - - S - - - Protein of unknown function (DUF1797)
MHGHIHEH_02849 1.56e-277 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHGHIHEH_02851 1.58e-220 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHGHIHEH_02852 1.13e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MHGHIHEH_02853 1.09e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MHGHIHEH_02854 0.0 ybeC - - E - - - amino acid
MHGHIHEH_02855 2.38e-122 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
MHGHIHEH_02866 3.38e-40 - - - - - - - -
MHGHIHEH_02868 4.43e-23 - - - - - - - -
MHGHIHEH_02870 6.27e-81 - - - S - - - Protein of unknown function (DUF1642)
MHGHIHEH_02872 9.27e-86 - - - S - - - magnesium ion binding
MHGHIHEH_02873 6.07e-49 - - - - - - - -
MHGHIHEH_02874 5.02e-60 - - - - - - - -
MHGHIHEH_02875 6.14e-09 - - - K - - - Cro/C1-type HTH DNA-binding domain
MHGHIHEH_02877 3.06e-92 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHGHIHEH_02878 1.12e-89 - - - L - - - Domain of unknown function (DUF4373)
MHGHIHEH_02879 6.3e-174 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
MHGHIHEH_02880 4.63e-180 - - - L ko:K07455 - ko00000,ko03400 RecT family
MHGHIHEH_02883 4.92e-21 - - - - - - - -
MHGHIHEH_02885 1.82e-126 - - - - - - - -
MHGHIHEH_02889 6.25e-47 - - - K - - - Helix-turn-helix domain
MHGHIHEH_02890 1.42e-71 - - - K - - - Helix-turn-helix domain
MHGHIHEH_02891 1.39e-91 - - - E - - - Zn peptidase
MHGHIHEH_02893 4.81e-275 int3 - - L - - - Belongs to the 'phage' integrase family
MHGHIHEH_02894 1.64e-263 - - - V - - - Abi-like protein
MHGHIHEH_02895 1.68e-94 - - - - - - - -
MHGHIHEH_02896 4.14e-15 - - - - - - - -
MHGHIHEH_02897 1.09e-23 - - - - - - - -
MHGHIHEH_02898 1.38e-110 - - - J ko:K10716 - ko00000,ko02000 Ion transport protein
MHGHIHEH_02900 1.03e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
MHGHIHEH_02902 1.67e-162 - - - K - - - Transcriptional regulator
MHGHIHEH_02904 3.74e-52 - - - S - - - Domain of unknown function (DUF771)
MHGHIHEH_02907 7.64e-88 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MHGHIHEH_02908 3.45e-118 - - - - - - - -
MHGHIHEH_02909 3.83e-61 - - - L - - - BRCA1 C Terminus (BRCT) domain
MHGHIHEH_02910 1.14e-148 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MHGHIHEH_02911 2.25e-64 - - - S - - - Protein of unknown function (DUF1093)
MHGHIHEH_02913 4e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MHGHIHEH_02915 3.94e-14 - - - C - - - Zinc-binding dehydrogenase
MHGHIHEH_02916 3.67e-93 - - - S - - - pyridoxamine 5-phosphate
MHGHIHEH_02917 5.79e-307 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MHGHIHEH_02918 6.44e-139 - - - S - - - NADPH-dependent FMN reductase
MHGHIHEH_02919 9.99e-208 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHGHIHEH_02920 0.0 - - - L ko:K07459 - ko00000 AAA ATPase domain
MHGHIHEH_02921 0.0 - - - L - - - UvrD/REP helicase N-terminal domain
MHGHIHEH_02922 4.92e-167 - - - K - - - DeoR C terminal sensor domain
MHGHIHEH_02924 3.03e-65 lciIC - - K - - - Helix-turn-helix domain
MHGHIHEH_02925 9.14e-26 - - - S - - - Adenine-specific methyltransferase EcoRI
MHGHIHEH_02926 1.28e-145 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_02927 2.42e-163 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MHGHIHEH_02928 4.27e-309 xylP - - G - - - MFS/sugar transport protein
MHGHIHEH_02929 2.14e-177 - - - S - - - ORF6N domain
MHGHIHEH_02930 1.66e-59 - - - S - - - Domain of unknown function (DUF1883)
MHGHIHEH_02937 5.93e-12 - - - - - - - -
MHGHIHEH_02938 5.12e-129 arsA 3.6.3.16 - D ko:K01551 - ko00000,ko01000,ko02000 Anion-transporting ATPase
MHGHIHEH_02939 3.29e-297 arsB - - U ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHGHIHEH_02940 1.01e-73 - - - S - - - Arsenical resistance operon trans-acting repressor ArsD
MHGHIHEH_02941 2.14e-97 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHGHIHEH_02942 0.0 choS - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHGHIHEH_02943 6.07e-225 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHGHIHEH_02944 3.7e-96 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MHGHIHEH_02945 1.56e-45 - - - - - - - -
MHGHIHEH_02948 1.51e-80 - - - K - - - Helix-turn-helix XRE-family like proteins
MHGHIHEH_02949 2.33e-25 - - - E - - - Zn peptidase
MHGHIHEH_02950 6.12e-110 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MHGHIHEH_02951 9.03e-11 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
MHGHIHEH_02952 4.1e-162 - - - M - - - domain protein
MHGHIHEH_02953 3.9e-269 yvcC - - M - - - Cna protein B-type domain
MHGHIHEH_02954 1.56e-93 - - - - - - - -
MHGHIHEH_02955 1.75e-171 - - - - - - - -
MHGHIHEH_02957 1.45e-46 - - - - - - - -
MHGHIHEH_02958 4.72e-83 is18 - - L - - - COG2801 Transposase and inactivated derivatives
MHGHIHEH_02959 1.23e-135 - - - - - - - -
MHGHIHEH_02961 2.97e-93 - - - M - - - LPXTG cell wall anchor motif
MHGHIHEH_02962 1.23e-48 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MHGHIHEH_02963 7.69e-134 - - - - - - - -
MHGHIHEH_02964 2.15e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MHGHIHEH_02965 9.06e-99 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
MHGHIHEH_02973 1.8e-85 - - - L - - - Integrase core domain
MHGHIHEH_02980 2.2e-81 - - - L - - - Transposase DDE domain
MHGHIHEH_02981 6.97e-85 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)