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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MDBHGFCO_00005	3.1e-276	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDBHGFCO_00006	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
MDBHGFCO_00007	1.4e-163	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MDBHGFCO_00008	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MDBHGFCO_00009	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MDBHGFCO_00010	4.29e-277	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MDBHGFCO_00011	2.27e-164	-	-	-	-	-	-	-	-
MDBHGFCO_00012	1.26e-190	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDBHGFCO_00013	4.63e-160	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MDBHGFCO_00014	1.6e-219	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDBHGFCO_00015	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MDBHGFCO_00016	3.12e-220	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MDBHGFCO_00017	4.75e-67	-	-	-	-	-	-	-	-
MDBHGFCO_00018	7.51e-96	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MDBHGFCO_00019	3.81e-73	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MDBHGFCO_00021	3.04e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MDBHGFCO_00022	3.72e-166	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
MDBHGFCO_00023	5.47e-144	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
MDBHGFCO_00024	2.16e-108	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MDBHGFCO_00025	9.98e-246	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MDBHGFCO_00026	4.71e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MDBHGFCO_00027	6.4e-210	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MDBHGFCO_00028	1.85e-169	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
MDBHGFCO_00029	6.63e-188	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MDBHGFCO_00030	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MDBHGFCO_00031	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MDBHGFCO_00032	1.14e-104	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MDBHGFCO_00033	4.3e-170	-	-	-	G	-	-	-	Major Facilitator Superfamily
MDBHGFCO_00034	4.4e-112	-	-	-	S	-	-	-	phospholipase Carboxylesterase
MDBHGFCO_00035	4.53e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDBHGFCO_00036	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MDBHGFCO_00037	3.68e-101	-	-	-	K	-	-	-	acetyltransferase
MDBHGFCO_00038	6.12e-185	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MDBHGFCO_00039	6.9e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
MDBHGFCO_00040	1.99e-193	-	-	-	S	-	-	-	hydrolase
MDBHGFCO_00041	6.07e-170	-	-	-	K	-	-	-	Transcriptional regulator
MDBHGFCO_00042	1.81e-307	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MDBHGFCO_00043	2.29e-176	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
MDBHGFCO_00044	9.37e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
MDBHGFCO_00045	2.86e-137	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
MDBHGFCO_00046	2.93e-165	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
MDBHGFCO_00047	1.71e-111	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDBHGFCO_00048	6.32e-68	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDBHGFCO_00049	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MDBHGFCO_00050	3.59e-52	-	-	-	-	-	-	-	-
MDBHGFCO_00051	1.33e-192	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
MDBHGFCO_00052	6.12e-76	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
MDBHGFCO_00053	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
MDBHGFCO_00054	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDBHGFCO_00055	2.5e-257	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MDBHGFCO_00056	2.17e-210	-	-	-	K	-	-	-	LysR family
MDBHGFCO_00057	0.0	-	-	-	C	-	-	-	FMN_bind
MDBHGFCO_00058	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MDBHGFCO_00059	1.73e-42	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MDBHGFCO_00060	5.19e-132	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MDBHGFCO_00061	2.28e-226	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
MDBHGFCO_00062	5.43e-118	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
MDBHGFCO_00063	6.45e-69	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
MDBHGFCO_00064	3.51e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
MDBHGFCO_00065	0.0	-	-	-	E	-	-	-	Phospholipase B
MDBHGFCO_00066	8.72e-314	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MDBHGFCO_00067	1.1e-180	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
MDBHGFCO_00068	2.5e-29	-	-	-	G	-	-	-	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_00069	3.43e-89	-	-	-	G	-	-	-	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_00070	2.65e-31	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDBHGFCO_00071	4.47e-18	-	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
MDBHGFCO_00072	1.64e-71	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDBHGFCO_00073	2.73e-54	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDBHGFCO_00074	7.63e-271	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MDBHGFCO_00076	2.23e-130	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
MDBHGFCO_00077	2.32e-125	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MDBHGFCO_00078	7.08e-312	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
MDBHGFCO_00079	1.28e-189	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDBHGFCO_00080	2.42e-190	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDBHGFCO_00081	1.77e-152	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDBHGFCO_00082	4.43e-139	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDBHGFCO_00083	3.65e-21	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_00084	0.0	-	-	-	E	-	-	-	Amino acid permease
MDBHGFCO_00085	1.27e-273	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MDBHGFCO_00086	9.79e-37	-	-	-	-	-	-	-	-
MDBHGFCO_00087	5.62e-93	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDBHGFCO_00088	4.5e-106	-	-	-	-	-	-	-	-
MDBHGFCO_00089	3.73e-263	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
MDBHGFCO_00091	5.16e-115	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MDBHGFCO_00092	1.4e-155	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
MDBHGFCO_00093	1.49e-194	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
MDBHGFCO_00094	2.38e-94	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MDBHGFCO_00095	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MDBHGFCO_00096	5.45e-232	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MDBHGFCO_00097	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Glycosyl hydrolases family 31
MDBHGFCO_00098	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MDBHGFCO_00099	4.66e-264	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
MDBHGFCO_00100	2.91e-199	-	-	-	S	-	-	-	Alpha beta hydrolase
MDBHGFCO_00101	5.36e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MDBHGFCO_00102	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00103	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MDBHGFCO_00104	1.56e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDBHGFCO_00105	4.37e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00106	6.83e-191	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDBHGFCO_00107	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00108	7.95e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00109	1.77e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_00110	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MDBHGFCO_00111	3.51e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
MDBHGFCO_00112	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDBHGFCO_00113	6.68e-128	-	-	-	S	-	-	-	Putative adhesin
MDBHGFCO_00114	5.37e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MDBHGFCO_00115	1.42e-259	-	-	-	EGP	-	-	-	Major facilitator superfamily
MDBHGFCO_00117	1.97e-70	-	-	-	S	-	-	-	Enterocin A Immunity
MDBHGFCO_00118	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MDBHGFCO_00119	6.46e-206	-	-	-	S	-	-	-	Phospholipase, patatin family
MDBHGFCO_00120	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00121	2.68e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00122	1.82e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDBHGFCO_00123	1.18e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MDBHGFCO_00124	7.19e-216	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MDBHGFCO_00125	2.05e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MDBHGFCO_00126	1.57e-189	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDBHGFCO_00127	2.13e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDBHGFCO_00128	4.1e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MDBHGFCO_00129	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MDBHGFCO_00130	1.1e-107	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MDBHGFCO_00132	1.58e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDBHGFCO_00133	8.05e-166	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDBHGFCO_00134	1.35e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MDBHGFCO_00135	2.4e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MDBHGFCO_00136	7.47e-70	-	-	-	S	-	-	-	Enterocin A Immunity
MDBHGFCO_00137	3.92e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MDBHGFCO_00138	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MDBHGFCO_00139	5.9e-152	-	-	-	C	-	-	-	nitroreductase
MDBHGFCO_00140	1.62e-170	-	-	-	-	-	-	-	-
MDBHGFCO_00141	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MDBHGFCO_00142	1e-131	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MDBHGFCO_00143	6.55e-299	-	-	-	E	ko:K03294	-	ko00000	amino acid
MDBHGFCO_00144	3.55e-176	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MDBHGFCO_00145	1.29e-276	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MDBHGFCO_00146	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_00149	4.69e-277	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDBHGFCO_00150	6.32e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
MDBHGFCO_00151	2.75e-100	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MDBHGFCO_00152	2.09e-207	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MDBHGFCO_00153	5.32e-213	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MDBHGFCO_00154	1.94e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MDBHGFCO_00155	1.84e-198	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_00156	5.87e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00157	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDBHGFCO_00158	6.2e-89	-	-	-	O	-	-	-	OsmC-like protein
MDBHGFCO_00159	1.09e-55	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
MDBHGFCO_00160	6.72e-146	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
MDBHGFCO_00161	1.18e-148	dltr	-	-	K	-	-	-	response regulator
MDBHGFCO_00162	6.39e-299	sptS	-	-	T	-	-	-	Histidine kinase
MDBHGFCO_00163	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDBHGFCO_00164	8.55e-88	-	-	-	-	-	-	-	-
MDBHGFCO_00165	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MDBHGFCO_00166	1.23e-181	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDBHGFCO_00167	1.13e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDBHGFCO_00169	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDBHGFCO_00170	2.46e-95	-	-	-	-	-	-	-	-
MDBHGFCO_00171	1.26e-139	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MDBHGFCO_00172	7.24e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MDBHGFCO_00173	2.83e-165	pnb	-	-	C	-	-	-	nitroreductase
MDBHGFCO_00174	1.05e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MDBHGFCO_00175	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MDBHGFCO_00176	1.88e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MDBHGFCO_00177	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDBHGFCO_00178	6.93e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MDBHGFCO_00179	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MDBHGFCO_00180	2.97e-214	-	-	-	GK	-	-	-	ROK family
MDBHGFCO_00181	4.56e-211	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MDBHGFCO_00182	1.96e-223	-	-	-	I	-	-	-	Carboxylesterase family
MDBHGFCO_00183	1.05e-260	-	-	-	P	-	-	-	Major Facilitator Superfamily
MDBHGFCO_00184	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MDBHGFCO_00185	3.81e-73	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDBHGFCO_00186	1.59e-77	-	-	-	-	-	-	-	-
MDBHGFCO_00187	1.39e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MDBHGFCO_00188	4.96e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MDBHGFCO_00189	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MDBHGFCO_00190	4.08e-18	-	-	-	-	-	-	-	-
MDBHGFCO_00191	2.89e-310	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MDBHGFCO_00192	1.89e-192	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDBHGFCO_00193	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MDBHGFCO_00194	1.67e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MDBHGFCO_00195	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MDBHGFCO_00196	2.4e-253	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MDBHGFCO_00197	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDBHGFCO_00198	1.47e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MDBHGFCO_00199	1.42e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDBHGFCO_00200	2.23e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDBHGFCO_00201	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDBHGFCO_00202	1.93e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDBHGFCO_00203	1.46e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDBHGFCO_00204	1.85e-199	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MDBHGFCO_00205	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MDBHGFCO_00206	8.55e-64	-	-	-	-	-	-	-	-
MDBHGFCO_00207	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MDBHGFCO_00208	1.63e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDBHGFCO_00209	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDBHGFCO_00210	8.3e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDBHGFCO_00211	3e-308	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDBHGFCO_00212	1.5e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MDBHGFCO_00213	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MDBHGFCO_00214	9.16e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDBHGFCO_00215	2.24e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MDBHGFCO_00216	2.14e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MDBHGFCO_00217	9.04e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MDBHGFCO_00218	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MDBHGFCO_00219	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MDBHGFCO_00220	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDBHGFCO_00221	1.01e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDBHGFCO_00222	6.2e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDBHGFCO_00223	4.35e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDBHGFCO_00224	2.91e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDBHGFCO_00225	3.16e-232	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00226	2.73e-209	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDBHGFCO_00227	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDBHGFCO_00228	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDBHGFCO_00229	5.24e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDBHGFCO_00230	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MDBHGFCO_00231	1.18e-225	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDBHGFCO_00232	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDBHGFCO_00233	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDBHGFCO_00234	6.63e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDBHGFCO_00235	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MDBHGFCO_00236	2.07e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDBHGFCO_00237	3.13e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MDBHGFCO_00238	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDBHGFCO_00239	8.67e-150	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDBHGFCO_00240	1.68e-98	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
MDBHGFCO_00241	1.91e-149	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MDBHGFCO_00242	3.88e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDBHGFCO_00243	2.31e-44	ynzC	-	-	S	-	-	-	UPF0291 protein
MDBHGFCO_00244	4.85e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MDBHGFCO_00245	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDBHGFCO_00246	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDBHGFCO_00247	1.31e-286	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MDBHGFCO_00248	3.62e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MDBHGFCO_00249	1.87e-249	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MDBHGFCO_00250	3.06e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MDBHGFCO_00251	3.97e-232	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDBHGFCO_00252	7.13e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MDBHGFCO_00253	2.87e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDBHGFCO_00254	5.68e-174	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDBHGFCO_00255	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MDBHGFCO_00256	3.66e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MDBHGFCO_00257	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDBHGFCO_00258	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDBHGFCO_00259	2.25e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MDBHGFCO_00260	6.72e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MDBHGFCO_00261	2.17e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MDBHGFCO_00262	8.97e-62	-	-	-	J	-	-	-	ribosomal protein
MDBHGFCO_00263	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDBHGFCO_00264	6.74e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDBHGFCO_00265	2.35e-211	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDBHGFCO_00266	2.38e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MDBHGFCO_00267	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MDBHGFCO_00268	8.16e-154	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MDBHGFCO_00269	4.59e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDBHGFCO_00270	9.65e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDBHGFCO_00271	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MDBHGFCO_00272	3.33e-250	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDBHGFCO_00273	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDBHGFCO_00274	2.21e-157	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MDBHGFCO_00275	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MDBHGFCO_00276	1.02e-124	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDBHGFCO_00277	0.0	potE	-	-	E	-	-	-	Amino Acid
MDBHGFCO_00278	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDBHGFCO_00279	1.41e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDBHGFCO_00280	1.4e-124	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDBHGFCO_00281	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MDBHGFCO_00282	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MDBHGFCO_00283	1.78e-203	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MDBHGFCO_00285	5.12e-132	-	-	-	I	-	-	-	PAP2 superfamily
MDBHGFCO_00286	6.08e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDBHGFCO_00287	9.84e-41	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
MDBHGFCO_00288	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MDBHGFCO_00289	1.16e-63	-	-	-	K	-	-	-	Helix-turn-helix domain
MDBHGFCO_00290	7.39e-192	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MDBHGFCO_00291	2.62e-121	-	-	-	L	-	-	-	nuclease
MDBHGFCO_00292	4.69e-200	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MDBHGFCO_00293	9.17e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDBHGFCO_00294	2.57e-126	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00295	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDBHGFCO_00296	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MDBHGFCO_00297	1.54e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MDBHGFCO_00298	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
MDBHGFCO_00299	4.36e-242	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MDBHGFCO_00300	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MDBHGFCO_00301	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MDBHGFCO_00302	6.91e-113	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDBHGFCO_00303	1.43e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MDBHGFCO_00304	4.69e-86	-	-	-	-	-	-	-	-
MDBHGFCO_00305	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDBHGFCO_00306	1.17e-95	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDBHGFCO_00307	5e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MDBHGFCO_00308	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDBHGFCO_00309	1.09e-117	-	-	-	-	-	-	-	-
MDBHGFCO_00310	1.22e-107	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MDBHGFCO_00311	1.94e-57	-	-	-	-	-	-	-	-
MDBHGFCO_00312	6.06e-89	-	-	-	-	-	-	-	-
MDBHGFCO_00313	2.89e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
MDBHGFCO_00314	1.15e-137	-	-	-	S	-	-	-	Rib/alpha-like repeat
MDBHGFCO_00315	8.73e-314	yagE	-	-	E	-	-	-	amino acid
MDBHGFCO_00316	2.47e-147	-	-	-	GM	-	-	-	NmrA-like family
MDBHGFCO_00317	3.3e-137	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
MDBHGFCO_00318	1.67e-221	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
MDBHGFCO_00319	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDBHGFCO_00320	8.5e-303	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDBHGFCO_00321	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MDBHGFCO_00322	2.29e-224	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDBHGFCO_00323	5.02e-185	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDBHGFCO_00324	1.1e-62	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MDBHGFCO_00325	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MDBHGFCO_00326	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDBHGFCO_00327	1.57e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MDBHGFCO_00328	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MDBHGFCO_00330	1.19e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDBHGFCO_00331	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MDBHGFCO_00332	1.65e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MDBHGFCO_00333	6.78e-218	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MDBHGFCO_00334	7.97e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
MDBHGFCO_00335	2.48e-172	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDBHGFCO_00336	1.46e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDBHGFCO_00337	1.79e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDBHGFCO_00338	7.08e-90	-	-	-	M	-	-	-	Lysin motif
MDBHGFCO_00339	2.16e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDBHGFCO_00340	4.18e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MDBHGFCO_00341	5.27e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MDBHGFCO_00342	3.93e-307	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MDBHGFCO_00343	7.91e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDBHGFCO_00344	4.73e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MDBHGFCO_00347	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MDBHGFCO_00348	2.62e-284	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MDBHGFCO_00349	1.24e-84	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MDBHGFCO_00350	4.55e-195	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDBHGFCO_00351	9.91e-49	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MDBHGFCO_00352	8.35e-43	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MDBHGFCO_00353	0.0	-	-	-	C	-	-	-	FMN_bind
MDBHGFCO_00354	1.11e-116	-	-	-	-	-	-	-	-
MDBHGFCO_00355	6.33e-137	-	-	-	-	-	-	-	-
MDBHGFCO_00356	1.35e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDBHGFCO_00357	1.3e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDBHGFCO_00358	5.61e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MDBHGFCO_00359	1.05e-192	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MDBHGFCO_00360	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MDBHGFCO_00361	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MDBHGFCO_00362	4.91e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDBHGFCO_00363	7.68e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDBHGFCO_00364	8.39e-197	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MDBHGFCO_00365	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDBHGFCO_00366	3.98e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDBHGFCO_00367	3.49e-218	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MDBHGFCO_00368	3.16e-114	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDBHGFCO_00369	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDBHGFCO_00370	3.4e-228	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MDBHGFCO_00371	4.77e-125	-	-	-	K	-	-	-	LysR substrate binding domain
MDBHGFCO_00372	1.17e-129	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MDBHGFCO_00374	3.65e-87	-	-	-	-	-	-	-	-
MDBHGFCO_00375	4.44e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MDBHGFCO_00376	5.81e-76	-	-	-	K	-	-	-	Transcriptional regulator
MDBHGFCO_00377	3.25e-64	-	-	-	-	-	-	-	-
MDBHGFCO_00378	2.17e-56	-	-	-	-	-	-	-	-
MDBHGFCO_00379	5.57e-55	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
MDBHGFCO_00380	4.7e-102	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_00381	1.42e-48	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_00382	7.44e-143	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00383	1.04e-167	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MDBHGFCO_00384	1.52e-125	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MDBHGFCO_00385	1.51e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MDBHGFCO_00386	2.11e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
MDBHGFCO_00387	1.21e-144	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MDBHGFCO_00388	0.0	-	-	-	S	-	-	-	domain, Protein
MDBHGFCO_00391	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDBHGFCO_00392	0.0	-	-	-	M	-	-	-	domain protein
MDBHGFCO_00393	0.0	-	-	-	-	-	-	-	-
MDBHGFCO_00394	5.55e-143	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
MDBHGFCO_00395	2.64e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MDBHGFCO_00396	6e-102	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MDBHGFCO_00397	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDBHGFCO_00398	2.96e-15	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDBHGFCO_00399	6.95e-111	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDBHGFCO_00400	9.19e-21	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MDBHGFCO_00401	6.78e-89	-	-	-	K	-	-	-	HxlR family
MDBHGFCO_00402	1.14e-63	-	-	-	-	-	-	-	-
MDBHGFCO_00403	2.05e-277	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
MDBHGFCO_00404	3.44e-16	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
MDBHGFCO_00405	3.95e-99	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
MDBHGFCO_00406	0.0	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
MDBHGFCO_00407	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDBHGFCO_00408	1.52e-94	-	-	-	S	-	-	-	Cupin domain
MDBHGFCO_00409	7.83e-240	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDBHGFCO_00410	4.45e-42	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
MDBHGFCO_00411	4.25e-42	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MDBHGFCO_00412	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MDBHGFCO_00413	2.81e-170	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MDBHGFCO_00414	3.42e-196	-	-	-	C	-	-	-	Aldo keto reductase
MDBHGFCO_00416	1.24e-129	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MDBHGFCO_00417	3.64e-295	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF1100)
MDBHGFCO_00418	6.65e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
MDBHGFCO_00419	6.57e-275	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
MDBHGFCO_00420	5.18e-76	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
MDBHGFCO_00421	2.7e-43	-	-	-	G	ko:K03292	-	ko00000	Major facilitator Superfamily
MDBHGFCO_00422	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
MDBHGFCO_00423	1.29e-96	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDBHGFCO_00424	3.87e-37	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MDBHGFCO_00425	9.67e-222	yobV3	-	-	K	-	-	-	WYL domain
MDBHGFCO_00426	5.89e-90	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
MDBHGFCO_00427	4.13e-147	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00428	1.44e-07	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MDBHGFCO_00429	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
MDBHGFCO_00430	9.51e-47	-	-	-	C	-	-	-	Heavy-metal-associated domain
MDBHGFCO_00431	1.13e-123	dpsB	-	-	P	-	-	-	Belongs to the Dps family
MDBHGFCO_00432	2.06e-143	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
MDBHGFCO_00433	2.24e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MDBHGFCO_00434	6.95e-36	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
MDBHGFCO_00435	6.69e-109	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDBHGFCO_00436	1.7e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDBHGFCO_00437	1.95e-310	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
MDBHGFCO_00438	2.63e-43	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MDBHGFCO_00439	3.66e-134	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MDBHGFCO_00440	3.39e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MDBHGFCO_00441	1.31e-69	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
MDBHGFCO_00443	2.63e-38	-	-	-	-	-	-	-	-
MDBHGFCO_00444	2.76e-37	-	-	-	K	-	-	-	Helix-turn-helix domain
MDBHGFCO_00445	1.24e-185	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MDBHGFCO_00446	1.07e-237	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDBHGFCO_00447	1.57e-150	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MDBHGFCO_00448	1.73e-156	-	-	-	C	-	-	-	Aldo/keto reductase family
MDBHGFCO_00449	1.96e-31	-	-	-	C	-	-	-	Aldo/keto reductase family
MDBHGFCO_00450	1.47e-211	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MDBHGFCO_00451	6.15e-153	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
MDBHGFCO_00452	8.12e-148	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MDBHGFCO_00453	3.54e-149	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDBHGFCO_00454	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDBHGFCO_00455	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDBHGFCO_00456	3.98e-229	-	-	-	K	-	-	-	Transcriptional regulator
MDBHGFCO_00457	3.5e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MDBHGFCO_00458	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MDBHGFCO_00459	6.77e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDBHGFCO_00460	1.5e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MDBHGFCO_00461	2.32e-259	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MDBHGFCO_00462	1.29e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
MDBHGFCO_00463	6.95e-197	-	-	-	-	-	-	-	-
MDBHGFCO_00464	1.3e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
MDBHGFCO_00465	1.16e-84	-	-	-	-	-	-	-	-
MDBHGFCO_00466	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MDBHGFCO_00467	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MDBHGFCO_00468	4.62e-252	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDBHGFCO_00469	5.58e-218	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDBHGFCO_00470	9.07e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDBHGFCO_00471	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MDBHGFCO_00472	2.74e-77	-	-	-	-	-	-	-	-
MDBHGFCO_00473	4.75e-222	degV1	-	-	S	-	-	-	DegV family
MDBHGFCO_00474	5.31e-306	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDBHGFCO_00475	1.61e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MDBHGFCO_00476	3.93e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDBHGFCO_00477	1.54e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MDBHGFCO_00478	1.63e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDBHGFCO_00479	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MDBHGFCO_00480	1.92e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDBHGFCO_00481	1.19e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MDBHGFCO_00482	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MDBHGFCO_00483	3.11e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MDBHGFCO_00484	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MDBHGFCO_00485	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MDBHGFCO_00486	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDBHGFCO_00487	1.8e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MDBHGFCO_00488	3.23e-221	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MDBHGFCO_00489	2.53e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MDBHGFCO_00490	2.24e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDBHGFCO_00491	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDBHGFCO_00492	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDBHGFCO_00493	4.72e-197	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MDBHGFCO_00494	3.86e-205	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
MDBHGFCO_00495	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDBHGFCO_00496	2.09e-109	-	-	-	S	-	-	-	ASCH
MDBHGFCO_00497	2.68e-175	-	-	-	F	-	-	-	Phosphorylase superfamily
MDBHGFCO_00498	4.39e-84	-	-	-	F	-	-	-	NUDIX domain
MDBHGFCO_00499	1.92e-106	-	-	-	S	-	-	-	AAA domain
MDBHGFCO_00500	8.35e-12	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MDBHGFCO_00501	2.63e-169	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MDBHGFCO_00502	1.55e-105	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
MDBHGFCO_00503	6.63e-122	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MDBHGFCO_00504	4.14e-07	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MDBHGFCO_00505	1.29e-29	-	-	-	S	-	-	-	Fic/DOC family
MDBHGFCO_00506	1.22e-159	-	-	-	-	-	-	-	-
MDBHGFCO_00507	4.24e-77	-	-	-	-	-	-	-	-
MDBHGFCO_00508	1.24e-62	-	-	-	S	-	-	-	MazG-like family
MDBHGFCO_00509	6.17e-179	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
MDBHGFCO_00510	7.58e-98	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDBHGFCO_00511	2.39e-64	-	-	-	-	-	-	-	-
MDBHGFCO_00512	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MDBHGFCO_00513	2.89e-110	yfhC	-	-	C	-	-	-	nitroreductase
MDBHGFCO_00514	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDBHGFCO_00515	4.49e-192	-	-	-	K	-	-	-	Helix-turn-helix domain
MDBHGFCO_00516	1.1e-181	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MDBHGFCO_00517	9.65e-181	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MDBHGFCO_00518	3.83e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
MDBHGFCO_00520	1.55e-75	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MDBHGFCO_00521	2.32e-179	-	-	-	-	-	-	-	-
MDBHGFCO_00522	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDBHGFCO_00523	2.25e-89	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
MDBHGFCO_00524	1.95e-64	-	-	-	-	-	-	-	-
MDBHGFCO_00525	1.01e-35	-	-	-	-	-	-	-	-
MDBHGFCO_00526	1.29e-151	-	-	-	C	-	-	-	nitroreductase
MDBHGFCO_00527	4.35e-272	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
MDBHGFCO_00528	1.97e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MDBHGFCO_00529	2.4e-149	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_00530	0.0	-	-	-	G	-	-	-	isomerase
MDBHGFCO_00531	1.94e-101	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MDBHGFCO_00532	1.02e-200	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDBHGFCO_00533	6.53e-290	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MDBHGFCO_00534	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MDBHGFCO_00535	5e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDBHGFCO_00536	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDBHGFCO_00537	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MDBHGFCO_00538	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00539	7.1e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00541	1.69e-158	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
MDBHGFCO_00542	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MDBHGFCO_00543	1.69e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
MDBHGFCO_00544	4.14e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDBHGFCO_00545	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MDBHGFCO_00546	2.64e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDBHGFCO_00547	5.38e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDBHGFCO_00548	4.33e-235	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MDBHGFCO_00549	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDBHGFCO_00550	1.98e-209	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDBHGFCO_00551	6.85e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDBHGFCO_00552	1.11e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDBHGFCO_00553	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MDBHGFCO_00554	1.02e-193	yxeH	-	-	S	-	-	-	hydrolase
MDBHGFCO_00555	5.57e-212	-	-	-	S	-	-	-	DUF218 domain
MDBHGFCO_00556	4.01e-65	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
MDBHGFCO_00557	3.14e-297	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MDBHGFCO_00558	2.09e-219	-	-	-	-	-	-	-	-
MDBHGFCO_00559	2.2e-171	-	-	-	-	-	-	-	-
MDBHGFCO_00560	2.56e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDBHGFCO_00561	5.93e-30	-	-	-	-	-	-	-	-
MDBHGFCO_00562	8.92e-140	-	-	-	-	-	-	-	-
MDBHGFCO_00563	1.45e-172	-	-	-	-	-	-	-	-
MDBHGFCO_00564	1.46e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MDBHGFCO_00565	2.1e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
MDBHGFCO_00566	9.99e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MDBHGFCO_00567	1.15e-195	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDBHGFCO_00568	8.72e-154	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MDBHGFCO_00569	4.58e-48	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MDBHGFCO_00570	4.02e-18	rnhA	-	-	L	ko:K06993	-	ko00000	Ribonuclease HI
MDBHGFCO_00571	1.47e-16	-	-	-	D	-	-	-	nuclear chromosome segregation
MDBHGFCO_00572	2.29e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDBHGFCO_00573	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDBHGFCO_00574	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MDBHGFCO_00575	1.82e-228	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MDBHGFCO_00576	1.19e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MDBHGFCO_00577	1.22e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDBHGFCO_00578	4.52e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDBHGFCO_00579	3.37e-222	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MDBHGFCO_00580	1.62e-78	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MDBHGFCO_00581	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MDBHGFCO_00582	9.43e-201	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDBHGFCO_00583	1.71e-206	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDBHGFCO_00584	5.14e-138	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDBHGFCO_00585	4.15e-183	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MDBHGFCO_00586	5.21e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MDBHGFCO_00587	3.19e-283	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDBHGFCO_00588	1.22e-42	-	-	-	-	-	-	-	-
MDBHGFCO_00589	9.25e-106	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
MDBHGFCO_00590	4.54e-196	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MDBHGFCO_00591	7.06e-138	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
MDBHGFCO_00592	1.02e-83	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
MDBHGFCO_00593	5.81e-145	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
MDBHGFCO_00594	2.63e-38	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
MDBHGFCO_00595	1.42e-184	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
MDBHGFCO_00596	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
MDBHGFCO_00597	1.01e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
MDBHGFCO_00598	1.12e-43	-	-	-	-	-	-	-	-
MDBHGFCO_00599	6.79e-124	-	-	-	S	-	-	-	glycosyl transferase family 2
MDBHGFCO_00600	6.53e-06	-	-	-	S	-	-	-	glycosyl transferase family 2
MDBHGFCO_00601	2.07e-23	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
MDBHGFCO_00602	2.48e-59	-	-	-	-	-	-	-	-
MDBHGFCO_00604	6.61e-14	-	-	-	-	-	-	-	-
MDBHGFCO_00605	1.26e-242	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDBHGFCO_00606	3.48e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MDBHGFCO_00607	4.2e-208	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDBHGFCO_00608	1.01e-267	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDBHGFCO_00609	3.92e-272	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
MDBHGFCO_00610	3.79e-225	-	-	-	V	-	-	-	Abi-like protein
MDBHGFCO_00611	3.27e-70	-	-	-	-	-	-	-	-
MDBHGFCO_00612	4.74e-65	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
MDBHGFCO_00613	4.89e-36	-	-	-	-	-	-	-	-
MDBHGFCO_00615	1.45e-172	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
MDBHGFCO_00617	1.05e-86	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDBHGFCO_00618	7.02e-107	-	-	-	S	-	-	-	Acyltransferase family
MDBHGFCO_00619	1.36e-65	-	-	-	S	-	-	-	Acyltransferase family
MDBHGFCO_00620	8.86e-306	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MDBHGFCO_00621	1.75e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MDBHGFCO_00622	9.73e-78	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MDBHGFCO_00623	2.58e-189	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
MDBHGFCO_00624	2.56e-210	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MDBHGFCO_00625	4.02e-188	-	-	-	M	-	-	-	Glycosyl transferases group 1
MDBHGFCO_00626	1.35e-208	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MDBHGFCO_00627	6.04e-174	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MDBHGFCO_00628	5.68e-155	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MDBHGFCO_00629	4.49e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MDBHGFCO_00630	1.62e-161	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MDBHGFCO_00631	7.84e-184	epsB	-	-	M	-	-	-	biosynthesis protein
MDBHGFCO_00632	4.19e-219	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDBHGFCO_00633	1.87e-96	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MDBHGFCO_00634	6.68e-205	-	-	-	-	-	-	-	-
MDBHGFCO_00635	1.75e-155	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MDBHGFCO_00636	2.59e-294	-	-	-	-	-	-	-	-
MDBHGFCO_00637	1.92e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MDBHGFCO_00638	1.01e-104	-	-	-	-	-	-	-	-
MDBHGFCO_00639	7.72e-114	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDBHGFCO_00640	2.54e-132	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MDBHGFCO_00641	2.5e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDBHGFCO_00642	1.79e-278	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDBHGFCO_00643	6.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDBHGFCO_00644	4.04e-206	-	-	-	-	-	-	-	-
MDBHGFCO_00645	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDBHGFCO_00646	1.44e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDBHGFCO_00647	1.97e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MDBHGFCO_00648	1.18e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MDBHGFCO_00649	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MDBHGFCO_00650	1.36e-125	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MDBHGFCO_00651	2.03e-227	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MDBHGFCO_00652	4.75e-112	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDBHGFCO_00653	7.11e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MDBHGFCO_00654	7.67e-69	ylbG	-	-	S	-	-	-	UPF0298 protein
MDBHGFCO_00655	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDBHGFCO_00656	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MDBHGFCO_00657	2.39e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDBHGFCO_00658	1.53e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MDBHGFCO_00659	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDBHGFCO_00660	5.4e-224	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MDBHGFCO_00661	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDBHGFCO_00662	1.98e-148	-	-	-	S	-	-	-	repeat protein
MDBHGFCO_00663	2.61e-160	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MDBHGFCO_00664	1.22e-277	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDBHGFCO_00665	1.8e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MDBHGFCO_00666	2.9e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MDBHGFCO_00667	1.68e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDBHGFCO_00669	6.31e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MDBHGFCO_00670	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MDBHGFCO_00671	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDBHGFCO_00672	8.32e-163	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MDBHGFCO_00673	1.33e-185	ylmH	-	-	S	-	-	-	S4 domain protein
MDBHGFCO_00674	1.93e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MDBHGFCO_00675	4.43e-95	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDBHGFCO_00676	2.47e-307	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDBHGFCO_00677	6.34e-310	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDBHGFCO_00678	1.96e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDBHGFCO_00679	2.01e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDBHGFCO_00680	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDBHGFCO_00681	1.82e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDBHGFCO_00682	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDBHGFCO_00683	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MDBHGFCO_00684	1.55e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDBHGFCO_00685	1.33e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MDBHGFCO_00686	7.67e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
MDBHGFCO_00687	1.66e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MDBHGFCO_00688	9.8e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
MDBHGFCO_00689	2.88e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MDBHGFCO_00690	2.19e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MDBHGFCO_00691	1.45e-143	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MDBHGFCO_00692	1.56e-160	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MDBHGFCO_00693	5.72e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MDBHGFCO_00694	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDBHGFCO_00695	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MDBHGFCO_00696	1.78e-264	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
MDBHGFCO_00697	5.88e-160	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDBHGFCO_00698	8.93e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDBHGFCO_00699	1.5e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MDBHGFCO_00700	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDBHGFCO_00702	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDBHGFCO_00703	3.45e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MDBHGFCO_00704	2.01e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MDBHGFCO_00705	2.34e-08	-	-	-	-	-	-	-	-
MDBHGFCO_00706	3.9e-106	uspA	-	-	T	-	-	-	universal stress protein
MDBHGFCO_00707	3.34e-287	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MDBHGFCO_00708	3.08e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MDBHGFCO_00709	6.72e-70	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MDBHGFCO_00710	2.97e-21	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
MDBHGFCO_00711	1.01e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MDBHGFCO_00712	3e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MDBHGFCO_00713	6.02e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MDBHGFCO_00714	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDBHGFCO_00715	1.21e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDBHGFCO_00716	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDBHGFCO_00717	7.97e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDBHGFCO_00718	1.25e-75	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDBHGFCO_00719	9.31e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDBHGFCO_00720	1.43e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MDBHGFCO_00721	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDBHGFCO_00722	9.87e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDBHGFCO_00723	7.23e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDBHGFCO_00724	1.27e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDBHGFCO_00725	5.77e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MDBHGFCO_00726	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
MDBHGFCO_00727	8.27e-240	ampC	-	-	V	-	-	-	Beta-lactamase
MDBHGFCO_00730	2.98e-94	-	-	-	-	-	-	-	-
MDBHGFCO_00731	3.78e-278	-	-	-	EGP	-	-	-	Major Facilitator
MDBHGFCO_00732	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MDBHGFCO_00733	1.52e-136	vanZ	-	-	V	-	-	-	VanZ like family
MDBHGFCO_00734	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDBHGFCO_00735	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MDBHGFCO_00736	1.56e-165	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MDBHGFCO_00737	9.78e-89	-	-	-	S	-	-	-	SdpI/YhfL protein family
MDBHGFCO_00738	4.38e-244	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDBHGFCO_00739	1.57e-117	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MDBHGFCO_00740	6.06e-47	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MDBHGFCO_00741	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
MDBHGFCO_00743	1.04e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDBHGFCO_00744	6.95e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MDBHGFCO_00745	3.7e-112	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MDBHGFCO_00747	1.45e-88	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MDBHGFCO_00748	4.94e-54	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
MDBHGFCO_00749	9.56e-226	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MDBHGFCO_00750	7.04e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MDBHGFCO_00751	2.13e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MDBHGFCO_00752	1.11e-126	-	-	-	S	-	-	-	VanZ like family
MDBHGFCO_00753	7.74e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDBHGFCO_00754	6.18e-207	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MDBHGFCO_00755	4.35e-192	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MDBHGFCO_00756	2.42e-148	-	-	-	-	-	-	-	-
MDBHGFCO_00757	2.94e-241	-	-	-	S	-	-	-	Putative adhesin
MDBHGFCO_00758	1.13e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDBHGFCO_00759	2.49e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDBHGFCO_00760	5.45e-187	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDBHGFCO_00761	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDBHGFCO_00762	1.55e-224	ybbR	-	-	S	-	-	-	YbbR-like protein
MDBHGFCO_00763	1.29e-196	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDBHGFCO_00764	1.71e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDBHGFCO_00765	5.35e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00766	1.22e-179	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00767	1.2e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDBHGFCO_00768	8.12e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MDBHGFCO_00769	2.61e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MDBHGFCO_00770	2.49e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MDBHGFCO_00771	3.67e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MDBHGFCO_00772	1.13e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDBHGFCO_00773	3.3e-201	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDBHGFCO_00774	1.41e-120	-	-	-	-	-	-	-	-
MDBHGFCO_00775	1.8e-134	-	-	-	-	-	-	-	-
MDBHGFCO_00777	1.38e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MDBHGFCO_00778	7.24e-102	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDBHGFCO_00779	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDBHGFCO_00780	1.07e-39	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MDBHGFCO_00781	3.39e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDBHGFCO_00782	8.39e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDBHGFCO_00783	1.42e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MDBHGFCO_00784	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDBHGFCO_00785	2.15e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MDBHGFCO_00787	0.0	ycaM	-	-	E	-	-	-	amino acid
MDBHGFCO_00788	3.07e-129	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDBHGFCO_00789	8.24e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MDBHGFCO_00790	1.88e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MDBHGFCO_00791	3.19e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MDBHGFCO_00792	1.44e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MDBHGFCO_00793	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDBHGFCO_00794	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDBHGFCO_00795	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDBHGFCO_00796	3.6e-242	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MDBHGFCO_00797	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MDBHGFCO_00798	1.02e-285	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDBHGFCO_00799	1.68e-229	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MDBHGFCO_00800	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
MDBHGFCO_00801	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
MDBHGFCO_00802	1.76e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MDBHGFCO_00803	9.3e-308	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_00804	7.34e-54	-	-	-	-	-	-	-	-
MDBHGFCO_00805	1.52e-274	-	-	-	E	-	-	-	Major Facilitator Superfamily
MDBHGFCO_00806	7.09e-223	pbpX2	-	-	V	-	-	-	Beta-lactamase
MDBHGFCO_00807	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDBHGFCO_00808	3.63e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDBHGFCO_00809	5.72e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MDBHGFCO_00810	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDBHGFCO_00811	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MDBHGFCO_00812	6.86e-60	-	-	-	-	-	-	-	-
MDBHGFCO_00813	3.29e-259	-	-	-	S	-	-	-	Membrane
MDBHGFCO_00814	6.26e-75	-	-	-	-	-	-	-	-
MDBHGFCO_00816	3.76e-55	-	-	-	-	-	-	-	-
MDBHGFCO_00818	2.47e-112	ykuL	-	-	S	-	-	-	(CBS) domain
MDBHGFCO_00819	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MDBHGFCO_00820	2.67e-255	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MDBHGFCO_00822	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MDBHGFCO_00823	1.19e-202	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDBHGFCO_00824	3.36e-43	-	-	-	-	-	-	-	-
MDBHGFCO_00825	1.37e-41	-	-	-	-	-	-	-	-
MDBHGFCO_00826	1.99e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDBHGFCO_00827	1.75e-202	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
MDBHGFCO_00828	3.9e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
MDBHGFCO_00829	2.45e-303	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MDBHGFCO_00830	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
MDBHGFCO_00831	9.16e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
MDBHGFCO_00832	8.24e-137	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDBHGFCO_00833	3.97e-255	-	-	-	S	-	-	-	DUF218 domain
MDBHGFCO_00834	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00835	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MDBHGFCO_00836	1.05e-231	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MDBHGFCO_00837	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MDBHGFCO_00838	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MDBHGFCO_00839	1.05e-224	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MDBHGFCO_00840	2.01e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
MDBHGFCO_00841	2.8e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MDBHGFCO_00842	1.84e-218	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MDBHGFCO_00843	3.94e-127	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
MDBHGFCO_00844	1.7e-152	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
MDBHGFCO_00845	3.29e-68	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MDBHGFCO_00846	1.58e-108	XK27_11925	-	-	V	-	-	-	Beta-lactamase
MDBHGFCO_00847	1.16e-242	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MDBHGFCO_00848	4.61e-166	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MDBHGFCO_00849	1.26e-190	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDBHGFCO_00850	9.68e-173	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDBHGFCO_00851	3.19e-24	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_00852	1.58e-200	-	-	-	S	-	-	-	Aldo/keto reductase family
MDBHGFCO_00853	2.44e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDBHGFCO_00854	7.19e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MDBHGFCO_00855	4.15e-162	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MDBHGFCO_00856	9.81e-302	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MDBHGFCO_00857	6.61e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDBHGFCO_00859	7.93e-117	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MDBHGFCO_00860	4.52e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDBHGFCO_00861	1.52e-58	-	-	-	I	-	-	-	bis(5'-adenosyl)-triphosphatase activity
MDBHGFCO_00862	6.17e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDBHGFCO_00863	7.81e-88	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDBHGFCO_00864	2.71e-266	-	-	-	G	ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MDBHGFCO_00865	2.37e-278	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
MDBHGFCO_00866	3.04e-96	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MDBHGFCO_00867	1.91e-109	-	-	-	-	-	-	-	-
MDBHGFCO_00868	1.58e-95	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MDBHGFCO_00869	4.71e-81	-	-	-	S	-	-	-	Cupredoxin-like domain
MDBHGFCO_00870	2.57e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
MDBHGFCO_00871	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MDBHGFCO_00872	7.15e-197	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
MDBHGFCO_00873	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MDBHGFCO_00874	0.0	-	-	-	E	-	-	-	Amino acid permease
MDBHGFCO_00875	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MDBHGFCO_00876	7.66e-312	ynbB	-	-	P	-	-	-	aluminum resistance
MDBHGFCO_00877	4.41e-96	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDBHGFCO_00878	7.21e-294	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MDBHGFCO_00879	9.59e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MDBHGFCO_00880	1.01e-311	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDBHGFCO_00881	1.3e-66	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDBHGFCO_00882	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MDBHGFCO_00883	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDBHGFCO_00884	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MDBHGFCO_00885	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDBHGFCO_00886	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDBHGFCO_00887	1.7e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDBHGFCO_00888	3.62e-79	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDBHGFCO_00889	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MDBHGFCO_00890	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDBHGFCO_00891	5.95e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDBHGFCO_00892	1.04e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MDBHGFCO_00893	3.74e-265	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDBHGFCO_00894	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDBHGFCO_00895	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDBHGFCO_00896	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MDBHGFCO_00897	7.47e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDBHGFCO_00898	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDBHGFCO_00899	2.75e-214	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MDBHGFCO_00900	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MDBHGFCO_00901	9.49e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MDBHGFCO_00902	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MDBHGFCO_00903	1.04e-217	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MDBHGFCO_00904	3.99e-279	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MDBHGFCO_00905	0.0	-	-	-	-	-	-	-	-
MDBHGFCO_00906	2.64e-151	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MDBHGFCO_00908	9.47e-144	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
MDBHGFCO_00909	4.18e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MDBHGFCO_00910	1.7e-117	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
MDBHGFCO_00911	4.27e-251	ydhF	-	-	S	-	-	-	Aldo keto reductase
MDBHGFCO_00913	4.01e-282	-	-	-	S	-	-	-	Sterol carrier protein domain
MDBHGFCO_00914	6.39e-150	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MDBHGFCO_00915	1.5e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MDBHGFCO_00916	5.28e-177	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MDBHGFCO_00917	4.65e-193	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
MDBHGFCO_00918	1.92e-26	-	-	-	-	-	-	-	-
MDBHGFCO_00919	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MDBHGFCO_00920	1.72e-214	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MDBHGFCO_00921	3.18e-19	-	-	-	S	-	-	-	CsbD-like
MDBHGFCO_00922	1.29e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
MDBHGFCO_00923	5.32e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MDBHGFCO_00924	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MDBHGFCO_00925	3.33e-210	-	-	-	S	-	-	-	Alpha beta hydrolase
MDBHGFCO_00926	3.66e-54	-	-	-	-	-	-	-	-
MDBHGFCO_00927	2.88e-229	ydbI	-	-	K	-	-	-	AI-2E family transporter
MDBHGFCO_00928	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
MDBHGFCO_00929	2.66e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDBHGFCO_00930	7.33e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDBHGFCO_00931	1.71e-246	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDBHGFCO_00932	0.0	-	-	-	S	-	-	-	domain, Protein
MDBHGFCO_00933	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDBHGFCO_00934	0.0	-	-	-	M	-	-	-	domain protein
MDBHGFCO_00935	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MDBHGFCO_00936	1.26e-216	-	-	-	K	-	-	-	LysR substrate binding domain
MDBHGFCO_00937	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MDBHGFCO_00938	5.19e-308	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDBHGFCO_00939	1.1e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDBHGFCO_00940	3.4e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MDBHGFCO_00941	1.21e-117	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MDBHGFCO_00942	4.34e-237	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MDBHGFCO_00943	4.68e-314	-	-	-	P	-	-	-	Major Facilitator Superfamily
MDBHGFCO_00944	1.23e-297	-	-	-	P	-	-	-	Major Facilitator Superfamily
MDBHGFCO_00945	4.74e-210	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
MDBHGFCO_00946	9.42e-232	-	-	-	M	-	-	-	Glycosyl transferase family 8
MDBHGFCO_00947	2.5e-234	-	-	-	M	-	-	-	Glycosyl transferase family 8
MDBHGFCO_00948	9.16e-202	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
MDBHGFCO_00949	3.57e-192	-	-	-	I	-	-	-	Acyl-transferase
MDBHGFCO_00951	3.03e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MDBHGFCO_00952	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDBHGFCO_00953	0.0	yycH	-	-	S	-	-	-	YycH protein
MDBHGFCO_00954	1.89e-189	yycI	-	-	S	-	-	-	YycH protein
MDBHGFCO_00955	5.27e-192	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MDBHGFCO_00956	1.72e-262	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MDBHGFCO_00957	3.01e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDBHGFCO_00958	4.44e-142	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MDBHGFCO_00959	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00960	3.01e-124	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MDBHGFCO_00961	7.05e-219	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MDBHGFCO_00962	1.93e-189	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MDBHGFCO_00963	2.19e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MDBHGFCO_00964	2.31e-240	ysdE	-	-	P	-	-	-	Citrate transporter
MDBHGFCO_00965	6.45e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MDBHGFCO_00966	1.14e-23	-	-	-	-	-	-	-	-
MDBHGFCO_00967	4.31e-197	-	-	-	-	-	-	-	-
MDBHGFCO_00969	1.43e-309	-	-	-	M	-	-	-	Glycosyl transferase
MDBHGFCO_00970	7.03e-269	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MDBHGFCO_00971	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MDBHGFCO_00972	2.73e-208	-	-	-	L	-	-	-	HNH nucleases
MDBHGFCO_00973	8.61e-176	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_00974	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDBHGFCO_00975	1.62e-135	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MDBHGFCO_00976	4.3e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MDBHGFCO_00977	2.16e-168	terC	-	-	P	-	-	-	Integral membrane protein TerC family
MDBHGFCO_00978	5.26e-123	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MDBHGFCO_00979	1.29e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MDBHGFCO_00980	7.71e-104	-	-	-	-	-	-	-	-
MDBHGFCO_00981	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDBHGFCO_00982	2.11e-158	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
MDBHGFCO_00983	2.39e-225	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MDBHGFCO_00984	2.23e-186	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDBHGFCO_00985	4.75e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MDBHGFCO_00986	3.33e-205	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDBHGFCO_00987	5.7e-160	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MDBHGFCO_00988	9.68e-83	-	-	-	-	-	-	-	-
MDBHGFCO_00989	3.01e-228	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDBHGFCO_00990	4.14e-267	-	-	-	S	-	-	-	CAAX protease self-immunity
MDBHGFCO_00991	1.37e-305	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MDBHGFCO_00992	4.82e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDBHGFCO_00993	4.9e-179	-	-	-	-	-	-	-	-
MDBHGFCO_00994	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MDBHGFCO_00995	5.41e-264	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MDBHGFCO_00996	4.18e-151	-	-	-	-	-	-	-	-
MDBHGFCO_00997	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MDBHGFCO_00998	6.39e-236	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MDBHGFCO_00999	1.61e-155	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MDBHGFCO_01000	6.44e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MDBHGFCO_01001	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MDBHGFCO_01002	8.33e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MDBHGFCO_01003	3.39e-275	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
MDBHGFCO_01004	2.64e-291	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDBHGFCO_01005	5.59e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MDBHGFCO_01006	1.87e-196	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
MDBHGFCO_01007	6.12e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
MDBHGFCO_01008	1.6e-89	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MDBHGFCO_01009	3.49e-23	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_01010	3.4e-276	-	-	-	S	-	-	-	zinc-ribbon domain
MDBHGFCO_01011	4.88e-241	-	-	-	-	-	-	-	-
MDBHGFCO_01012	5.43e-114	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MDBHGFCO_01013	1.89e-129	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDBHGFCO_01014	4.26e-171	-	-	-	K	-	-	-	UTRA domain
MDBHGFCO_01015	1.24e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MDBHGFCO_01016	4.96e-113	usp5	-	-	T	-	-	-	universal stress protein
MDBHGFCO_01018	9.6e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MDBHGFCO_01019	2.58e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDBHGFCO_01020	3.49e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDBHGFCO_01021	1.23e-188	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDBHGFCO_01022	6.97e-107	-	-	-	-	-	-	-	-
MDBHGFCO_01023	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDBHGFCO_01024	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MDBHGFCO_01025	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MDBHGFCO_01026	5.42e-82	-	-	-	-	-	-	-	-
MDBHGFCO_01027	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MDBHGFCO_01028	3.57e-176	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDBHGFCO_01029	1.83e-134	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MDBHGFCO_01030	4.42e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MDBHGFCO_01031	7.75e-210	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDBHGFCO_01032	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDBHGFCO_01033	2.19e-290	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDBHGFCO_01034	3.14e-236	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
MDBHGFCO_01035	8.88e-301	-	-	-	D	-	-	-	transport
MDBHGFCO_01036	9.83e-175	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDBHGFCO_01037	2.62e-209	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MDBHGFCO_01038	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDBHGFCO_01040	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MDBHGFCO_01041	6.45e-255	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
MDBHGFCO_01042	3.27e-281	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDBHGFCO_01043	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MDBHGFCO_01044	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MDBHGFCO_01045	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MDBHGFCO_01046	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MDBHGFCO_01047	1.06e-95	-	-	-	-	-	-	-	-
MDBHGFCO_01048	8.46e-162	-	-	-	-	-	-	-	-
MDBHGFCO_01049	1.75e-39	-	-	-	-	-	-	-	-
MDBHGFCO_01050	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MDBHGFCO_01051	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDBHGFCO_01052	0.0	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MDBHGFCO_01053	1.58e-87	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MDBHGFCO_01054	2.55e-185	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MDBHGFCO_01055	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MDBHGFCO_01056	1.44e-228	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MDBHGFCO_01057	5.78e-173	-	-	-	-	-	-	-	-
MDBHGFCO_01058	2.21e-189	-	-	-	-	-	-	-	-
MDBHGFCO_01059	4.49e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MDBHGFCO_01060	1.11e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDBHGFCO_01061	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDBHGFCO_01062	5.36e-92	-	-	-	S	-	-	-	GtrA-like protein
MDBHGFCO_01063	1.56e-227	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MDBHGFCO_01064	7.1e-152	-	-	-	-	-	-	-	-
MDBHGFCO_01065	5.21e-194	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MDBHGFCO_01066	1.73e-218	-	-	-	G	-	-	-	Aldose 1-epimerase
MDBHGFCO_01067	2.58e-257	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDBHGFCO_01068	3.1e-143	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDBHGFCO_01069	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MDBHGFCO_01070	1.53e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDBHGFCO_01072	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MDBHGFCO_01073	2.24e-160	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDBHGFCO_01074	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MDBHGFCO_01075	9.19e-78	-	-	-	-	-	-	-	-
MDBHGFCO_01076	4.87e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDBHGFCO_01077	1.47e-100	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MDBHGFCO_01078	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDBHGFCO_01079	2.82e-103	-	-	-	-	-	-	-	-
MDBHGFCO_01080	1.29e-315	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_01081	7.73e-164	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
MDBHGFCO_01082	1.4e-61	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
MDBHGFCO_01083	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDBHGFCO_01084	4.48e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MDBHGFCO_01085	1.76e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
MDBHGFCO_01086	4.67e-52	-	-	-	-	-	-	-	-
MDBHGFCO_01087	3.44e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDBHGFCO_01088	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_01089	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDBHGFCO_01090	2.02e-197	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MDBHGFCO_01091	1.05e-146	-	-	-	-	-	-	-	-
MDBHGFCO_01093	2.85e-147	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
MDBHGFCO_01094	4.06e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MDBHGFCO_01095	6.82e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
MDBHGFCO_01096	3.07e-129	-	-	-	S	ko:K06872	-	ko00000	TPM domain
MDBHGFCO_01097	3.57e-115	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MDBHGFCO_01098	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDBHGFCO_01099	5.69e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MDBHGFCO_01100	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDBHGFCO_01101	1.14e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDBHGFCO_01102	2.99e-49	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MDBHGFCO_01103	7.77e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MDBHGFCO_01104	1.08e-315	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDBHGFCO_01105	9.21e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDBHGFCO_01106	1.05e-227	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MDBHGFCO_01107	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MDBHGFCO_01108	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MDBHGFCO_01109	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MDBHGFCO_01110	2.69e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MDBHGFCO_01111	4.76e-269	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDBHGFCO_01112	1.58e-293	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDBHGFCO_01113	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDBHGFCO_01114	4.16e-199	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDBHGFCO_01115	3.11e-87	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
MDBHGFCO_01116	7.47e-286	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
MDBHGFCO_01117	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDBHGFCO_01118	3.89e-95	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MDBHGFCO_01119	3.78e-92	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDBHGFCO_01120	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDBHGFCO_01121	6.24e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDBHGFCO_01122	7.27e-302	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MDBHGFCO_01123	6.78e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDBHGFCO_01124	2.16e-170	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
MDBHGFCO_01125	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MDBHGFCO_01127	3.01e-228	-	-	-	K	-	-	-	Helix-turn-helix
MDBHGFCO_01128	7.98e-50	-	-	-	-	-	-	-	-
MDBHGFCO_01129	4.05e-89	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MDBHGFCO_01130	1.63e-121	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDBHGFCO_01131	7.35e-145	-	-	-	S	-	-	-	Flavodoxin-like fold
MDBHGFCO_01132	7.78e-63	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MDBHGFCO_01134	9.45e-67	-	-	-	-	-	-	-	-
MDBHGFCO_01135	5.66e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
MDBHGFCO_01136	3.72e-86	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MDBHGFCO_01137	1.2e-126	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDBHGFCO_01138	1.97e-123	-	-	-	-	-	-	-	-
MDBHGFCO_01139	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDBHGFCO_01140	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MDBHGFCO_01141	9.92e-266	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MDBHGFCO_01142	3.87e-51	-	-	-	-	-	-	-	-
MDBHGFCO_01143	1.85e-42	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDBHGFCO_01144	4.78e-225	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDBHGFCO_01145	1.67e-101	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MDBHGFCO_01146	1.41e-103	-	-	-	-	-	-	-	-
MDBHGFCO_01148	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDBHGFCO_01149	2.21e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDBHGFCO_01150	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MDBHGFCO_01151	6.15e-240	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MDBHGFCO_01152	1.2e-182	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDBHGFCO_01153	3.65e-173	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_01154	0.0	-	-	-	E	-	-	-	amino acid
MDBHGFCO_01155	1.28e-54	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MDBHGFCO_01156	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDBHGFCO_01157	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDBHGFCO_01158	1.44e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDBHGFCO_01159	4.83e-278	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDBHGFCO_01160	5.46e-161	-	-	-	S	-	-	-	(CBS) domain
MDBHGFCO_01161	2.31e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MDBHGFCO_01162	2.68e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDBHGFCO_01163	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDBHGFCO_01164	8.68e-47	yabO	-	-	J	-	-	-	S4 domain protein
MDBHGFCO_01165	5.29e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MDBHGFCO_01166	3.83e-79	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
MDBHGFCO_01167	3.28e-315	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDBHGFCO_01168	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDBHGFCO_01169	0.0	-	-	-	S	-	-	-	membrane
MDBHGFCO_01170	1.08e-153	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDBHGFCO_01171	1.1e-16	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDBHGFCO_01172	1.12e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDBHGFCO_01173	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MDBHGFCO_01176	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDBHGFCO_01177	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDBHGFCO_01178	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDBHGFCO_01179	2.89e-151	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MDBHGFCO_01180	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDBHGFCO_01181	1.14e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDBHGFCO_01182	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDBHGFCO_01183	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MDBHGFCO_01184	5.06e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDBHGFCO_01185	3.16e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MDBHGFCO_01186	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDBHGFCO_01187	4.01e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDBHGFCO_01188	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDBHGFCO_01189	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDBHGFCO_01190	3.04e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDBHGFCO_01191	4.26e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDBHGFCO_01192	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MDBHGFCO_01193	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDBHGFCO_01194	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDBHGFCO_01195	1.67e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDBHGFCO_01196	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDBHGFCO_01197	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDBHGFCO_01198	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDBHGFCO_01199	6.14e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDBHGFCO_01200	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDBHGFCO_01201	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDBHGFCO_01202	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MDBHGFCO_01203	1.66e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MDBHGFCO_01204	2.42e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDBHGFCO_01205	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDBHGFCO_01206	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDBHGFCO_01207	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MDBHGFCO_01208	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDBHGFCO_01209	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDBHGFCO_01210	2.19e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDBHGFCO_01211	3.85e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MDBHGFCO_01212	4.49e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDBHGFCO_01213	3.59e-206	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDBHGFCO_01214	2.19e-180	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDBHGFCO_01215	8.78e-195	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDBHGFCO_01216	7.82e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDBHGFCO_01217	7.96e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MDBHGFCO_01218	1.39e-94	-	-	-	-	-	-	-	-
MDBHGFCO_01219	2.95e-205	-	-	-	GM	-	-	-	NmrA-like family
MDBHGFCO_01220	1.27e-141	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MDBHGFCO_01221	7.46e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MDBHGFCO_01222	3.22e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MDBHGFCO_01223	5.88e-199	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MDBHGFCO_01224	2.66e-56	-	-	-	-	-	-	-	-
MDBHGFCO_01225	5.43e-35	-	-	-	-	-	-	-	-
MDBHGFCO_01226	4.28e-163	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDBHGFCO_01227	9.84e-236	-	-	-	S	-	-	-	AAA domain
MDBHGFCO_01228	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MDBHGFCO_01229	2.55e-176	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDBHGFCO_01230	3.67e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MDBHGFCO_01231	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDBHGFCO_01232	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDBHGFCO_01233	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MDBHGFCO_01234	2.73e-102	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDBHGFCO_01235	1.62e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDBHGFCO_01236	5.21e-195	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
MDBHGFCO_01237	5.42e-75	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
MDBHGFCO_01238	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
MDBHGFCO_01239	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDBHGFCO_01240	6.82e-128	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
MDBHGFCO_01241	1.19e-45	-	-	-	-	-	-	-	-
MDBHGFCO_01242	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MDBHGFCO_01243	2.15e-21	-	-	-	K	-	-	-	Cupin domain
MDBHGFCO_01244	2.68e-160	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_01245	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
MDBHGFCO_01246	2.04e-255	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MDBHGFCO_01247	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDBHGFCO_01248	8.29e-292	-	-	-	G	-	-	-	Major Facilitator Superfamily
MDBHGFCO_01249	1.52e-239	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDBHGFCO_01250	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MDBHGFCO_01251	9.78e-18	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDBHGFCO_01252	2.58e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MDBHGFCO_01253	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDBHGFCO_01254	6.1e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDBHGFCO_01255	5.35e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MDBHGFCO_01256	3.7e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MDBHGFCO_01257	7.71e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MDBHGFCO_01258	2.35e-126	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDBHGFCO_01259	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDBHGFCO_01260	4.14e-198	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
MDBHGFCO_01261	3.25e-44	-	-	-	-	-	-	-	-
MDBHGFCO_01262	3.19e-145	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MDBHGFCO_01263	6.96e-33	-	-	-	-	-	-	-	-
MDBHGFCO_01264	2.52e-106	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDBHGFCO_01265	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDBHGFCO_01266	9.41e-69	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDBHGFCO_01267	1.53e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDBHGFCO_01268	1.06e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MDBHGFCO_01269	4.1e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDBHGFCO_01270	8.23e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MDBHGFCO_01271	5.43e-195	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MDBHGFCO_01272	1.12e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MDBHGFCO_01273	2.41e-198	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDBHGFCO_01274	3.51e-166	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MDBHGFCO_01275	8.12e-113	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MDBHGFCO_01276	1.18e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MDBHGFCO_01277	1.4e-126	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MDBHGFCO_01278	2.88e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDBHGFCO_01279	1.58e-82	-	-	-	-	-	-	-	-
MDBHGFCO_01280	1.68e-209	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MDBHGFCO_01281	2.2e-304	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MDBHGFCO_01282	1.49e-64	-	-	-	-	-	-	-	-
MDBHGFCO_01283	1.2e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
MDBHGFCO_01284	1.41e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDBHGFCO_01285	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDBHGFCO_01286	3.81e-312	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDBHGFCO_01287	4.92e-99	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MDBHGFCO_01288	2.75e-64	-	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
MDBHGFCO_01289	2.89e-71	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MDBHGFCO_01290	7.65e-297	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDBHGFCO_01291	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MDBHGFCO_01292	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDBHGFCO_01293	2.47e-130	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MDBHGFCO_01294	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
MDBHGFCO_01295	1.12e-166	-	-	-	S	-	-	-	membrane
MDBHGFCO_01297	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDBHGFCO_01298	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDBHGFCO_01299	5.96e-09	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDBHGFCO_01300	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDBHGFCO_01301	5.53e-245	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
MDBHGFCO_01302	5.29e-153	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
MDBHGFCO_01303	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDBHGFCO_01304	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDBHGFCO_01305	1.26e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDBHGFCO_01306	1.16e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDBHGFCO_01307	1.89e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MDBHGFCO_01308	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDBHGFCO_01309	1.04e-266	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDBHGFCO_01310	2.84e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MDBHGFCO_01311	4.48e-298	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDBHGFCO_01312	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDBHGFCO_01313	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MDBHGFCO_01314	1.01e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDBHGFCO_01315	1.27e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MDBHGFCO_01316	1.81e-116	cvpA	-	-	S	-	-	-	Colicin V production protein
MDBHGFCO_01317	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDBHGFCO_01318	6.29e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MDBHGFCO_01319	2.57e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MDBHGFCO_01320	1.89e-185	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MDBHGFCO_01321	2.34e-148	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDBHGFCO_01322	9.77e-277	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDBHGFCO_01323	1.19e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MDBHGFCO_01324	2.54e-33	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDBHGFCO_01325	1.47e-67	-	-	-	-	-	-	-	-
MDBHGFCO_01326	1.54e-270	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MDBHGFCO_01327	1.45e-228	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MDBHGFCO_01328	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
MDBHGFCO_01329	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MDBHGFCO_01330	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MDBHGFCO_01331	3.99e-74	-	-	-	-	-	-	-	-
MDBHGFCO_01332	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDBHGFCO_01333	1.44e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MDBHGFCO_01334	1.98e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDBHGFCO_01335	1.09e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MDBHGFCO_01336	1.45e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MDBHGFCO_01337	1.03e-228	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MDBHGFCO_01338	2.37e-79	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
MDBHGFCO_01340	4.34e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MDBHGFCO_01341	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MDBHGFCO_01342	2.46e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MDBHGFCO_01343	4.26e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MDBHGFCO_01344	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MDBHGFCO_01345	1.68e-310	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MDBHGFCO_01346	1.19e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MDBHGFCO_01347	6.26e-306	-	-	-	E	-	-	-	amino acid
MDBHGFCO_01348	3.99e-299	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDBHGFCO_01349	2.39e-246	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MDBHGFCO_01350	1.52e-207	-	-	-	EG	-	-	-	EamA-like transporter family
MDBHGFCO_01351	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MDBHGFCO_01352	8.43e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MDBHGFCO_01353	1.87e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MDBHGFCO_01354	8.08e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MDBHGFCO_01355	1.47e-37	sigL	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MDBHGFCO_01356	4.13e-237	-	-	-	K	-	-	-	Sigma-54 interaction domain
MDBHGFCO_01357	2.87e-28	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MDBHGFCO_01358	4.13e-42	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
MDBHGFCO_01359	1.47e-45	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
MDBHGFCO_01360	3.57e-74	-	-	-	G	ko:K19509	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	IID component
MDBHGFCO_01361	8.69e-67	-	-	-	G	-	-	-	polysaccharide catabolic process
MDBHGFCO_01362	1.19e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MDBHGFCO_01363	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MDBHGFCO_01364	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDBHGFCO_01365	1.21e-115	ymdB	-	-	S	-	-	-	Macro domain protein
MDBHGFCO_01366	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MDBHGFCO_01367	3.27e-158	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MDBHGFCO_01368	1.31e-287	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MDBHGFCO_01369	3.39e-199	-	-	-	-	-	-	-	-
MDBHGFCO_01370	5.74e-71	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
MDBHGFCO_01371	1.81e-220	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MDBHGFCO_01372	9.8e-197	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDBHGFCO_01373	4.85e-182	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MDBHGFCO_01374	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MDBHGFCO_01375	6.19e-208	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MDBHGFCO_01376	1.91e-167	-	-	-	-	-	-	-	-
MDBHGFCO_01377	4.81e-69	-	-	-	-	-	-	-	-
MDBHGFCO_01378	1.67e-178	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MDBHGFCO_01379	1.58e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MDBHGFCO_01380	1.03e-179	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
MDBHGFCO_01381	8.8e-149	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MDBHGFCO_01382	6.75e-144	-	-	-	G	-	-	-	phosphoglycerate mutase
MDBHGFCO_01383	2.72e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDBHGFCO_01384	3.39e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MDBHGFCO_01385	4.28e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_01386	5.09e-203	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MDBHGFCO_01387	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDBHGFCO_01388	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDBHGFCO_01389	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDBHGFCO_01390	6.73e-51	-	-	-	-	-	-	-	-
MDBHGFCO_01391	6.92e-141	-	-	-	K	-	-	-	WHG domain
MDBHGFCO_01392	7.73e-127	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MDBHGFCO_01393	6.32e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MDBHGFCO_01394	7.68e-253	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MDBHGFCO_01395	1.06e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MDBHGFCO_01396	1.33e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDBHGFCO_01397	1.5e-123	cvpA	-	-	S	-	-	-	Colicin V production protein
MDBHGFCO_01398	3.39e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MDBHGFCO_01399	1.28e-197	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MDBHGFCO_01400	7.1e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MDBHGFCO_01401	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MDBHGFCO_01402	2.58e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MDBHGFCO_01403	3.81e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDBHGFCO_01404	9e-190	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MDBHGFCO_01405	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_01406	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MDBHGFCO_01407	2.39e-156	vanR	-	-	K	-	-	-	response regulator
MDBHGFCO_01408	1.85e-264	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MDBHGFCO_01409	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDBHGFCO_01410	1.29e-184	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MDBHGFCO_01411	5.34e-213	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_01412	5.06e-281	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDBHGFCO_01413	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MDBHGFCO_01414	2.29e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MDBHGFCO_01415	5.13e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDBHGFCO_01416	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MDBHGFCO_01417	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MDBHGFCO_01418	1.17e-178	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MDBHGFCO_01419	4.8e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MDBHGFCO_01420	8.64e-208	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MDBHGFCO_01421	1.83e-151	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDBHGFCO_01422	1.79e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MDBHGFCO_01423	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MDBHGFCO_01424	3.19e-88	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_01425	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MDBHGFCO_01426	1.04e-271	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDBHGFCO_01427	6.6e-53	-	-	-	-	-	-	-	-
MDBHGFCO_01428	7.55e-82	-	-	-	-	-	-	-	-
MDBHGFCO_01429	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MDBHGFCO_01430	9.33e-179	-	-	-	S	-	-	-	Putative threonine/serine exporter
MDBHGFCO_01431	1.1e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MDBHGFCO_01432	5.2e-54	-	-	-	-	-	-	-	-
MDBHGFCO_01433	3.75e-79	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDBHGFCO_01434	9.6e-106	-	-	-	-	-	-	-	-
MDBHGFCO_01435	5.84e-231	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDBHGFCO_01436	3.86e-107	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MDBHGFCO_01437	1.11e-142	-	-	-	-	-	-	-	-
MDBHGFCO_01438	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
MDBHGFCO_01439	3.52e-58	-	-	-	-	-	-	-	-
MDBHGFCO_01440	7.11e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
MDBHGFCO_01442	2.24e-189	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MDBHGFCO_01443	9.97e-297	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MDBHGFCO_01444	3.7e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDBHGFCO_01445	0.0	-	-	-	E	-	-	-	Amino Acid
MDBHGFCO_01446	3.81e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_01447	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MDBHGFCO_01448	4.19e-160	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
MDBHGFCO_01449	2.45e-34	-	-	-	-	-	-	-	-
MDBHGFCO_01450	2.35e-69	-	-	-	-	-	-	-	-
MDBHGFCO_01451	1.79e-190	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MDBHGFCO_01452	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MDBHGFCO_01453	4.66e-164	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MDBHGFCO_01454	1.38e-186	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDBHGFCO_01455	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MDBHGFCO_01456	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
MDBHGFCO_01458	4.34e-152	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MDBHGFCO_01459	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDBHGFCO_01460	9.08e-176	-	-	-	S	-	-	-	Peptidase_C39 like family
MDBHGFCO_01461	8.96e-152	-	-	-	K	ko:K02538	-	ko00000,ko03000	Mga helix-turn-helix domain
MDBHGFCO_01462	1.61e-54	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDBHGFCO_01463	2.59e-36	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDBHGFCO_01464	1.75e-234	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MDBHGFCO_01465	2.56e-125	-	-	-	S	-	-	-	protein containing SIS (Sugar ISomerase) phosphosugar binding domain
MDBHGFCO_01466	9.65e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDBHGFCO_01467	7.9e-212	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MDBHGFCO_01468	3.93e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDBHGFCO_01469	3.65e-127	-	-	-	M	-	-	-	Rib/alpha-like repeat
MDBHGFCO_01470	7.94e-202	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MDBHGFCO_01471	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDBHGFCO_01472	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDBHGFCO_01473	8.66e-204	-	-	-	EG	-	-	-	EamA-like transporter family
MDBHGFCO_01474	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDBHGFCO_01475	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MDBHGFCO_01476	1.73e-89	-	-	-	-	-	-	-	-
MDBHGFCO_01477	4.41e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDBHGFCO_01478	1.95e-272	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MDBHGFCO_01479	1.67e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDBHGFCO_01480	4.63e-169	-	-	-	S	-	-	-	PAS domain
MDBHGFCO_01481	3.1e-200	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_01482	1.11e-70	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDBHGFCO_01483	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MDBHGFCO_01484	1.7e-188	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MDBHGFCO_01485	6.12e-123	-	-	-	S	-	-	-	PAS domain
MDBHGFCO_01486	2.04e-313	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MDBHGFCO_01487	5.52e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MDBHGFCO_01488	7.18e-145	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDBHGFCO_01489	3.25e-181	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MDBHGFCO_01490	4.76e-213	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MDBHGFCO_01491	2.83e-230	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
MDBHGFCO_01492	8.33e-189	dkgB	-	-	S	-	-	-	reductase
MDBHGFCO_01493	1.46e-202	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MDBHGFCO_01494	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDBHGFCO_01495	9.41e-257	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MDBHGFCO_01496	4.34e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
MDBHGFCO_01497	3.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDBHGFCO_01498	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
MDBHGFCO_01499	1.38e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDBHGFCO_01500	7.83e-74	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MDBHGFCO_01501	1.84e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
MDBHGFCO_01502	2.29e-125	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MDBHGFCO_01503	1.27e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MDBHGFCO_01504	1.59e-214	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MDBHGFCO_01505	1.36e-214	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MDBHGFCO_01506	2.08e-126	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDBHGFCO_01507	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
MDBHGFCO_01508	2.53e-168	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDBHGFCO_01509	3.24e-159	-	-	-	S	-	-	-	SNARE associated Golgi protein
MDBHGFCO_01510	1.05e-229	-	-	-	-	-	-	-	-
MDBHGFCO_01511	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDBHGFCO_01512	2.86e-183	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MDBHGFCO_01513	3.06e-194	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MDBHGFCO_01514	5.97e-138	-	-	-	S	-	-	-	SNARE associated Golgi protein
MDBHGFCO_01515	2.7e-131	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MDBHGFCO_01516	1.07e-300	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDBHGFCO_01517	6.31e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDBHGFCO_01518	1.09e-238	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MDBHGFCO_01519	1.25e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDBHGFCO_01520	6.07e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDBHGFCO_01521	3.75e-49	-	-	-	-	-	-	-	-
MDBHGFCO_01522	8.75e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDBHGFCO_01523	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDBHGFCO_01524	2.35e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDBHGFCO_01525	2.15e-161	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MDBHGFCO_01526	1.03e-303	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MDBHGFCO_01527	1.39e-156	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MDBHGFCO_01528	9.48e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MDBHGFCO_01529	1.38e-312	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MDBHGFCO_01530	1.73e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDBHGFCO_01531	7.62e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDBHGFCO_01532	3.42e-171	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MDBHGFCO_01533	8.62e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MDBHGFCO_01534	2.58e-296	ymfH	-	-	S	-	-	-	Peptidase M16
MDBHGFCO_01535	4.27e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MDBHGFCO_01536	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MDBHGFCO_01537	8.29e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
MDBHGFCO_01538	1.88e-135	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDBHGFCO_01539	4.6e-271	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
MDBHGFCO_01540	2.67e-88	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MDBHGFCO_01541	6.1e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MDBHGFCO_01542	8.67e-297	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MDBHGFCO_01543	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MDBHGFCO_01544	9.68e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDBHGFCO_01545	2.24e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDBHGFCO_01546	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MDBHGFCO_01547	2.15e-144	-	-	-	S	-	-	-	CYTH
MDBHGFCO_01548	1.27e-138	yjbH	-	-	Q	-	-	-	Thioredoxin
MDBHGFCO_01549	4.94e-209	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MDBHGFCO_01550	2.82e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDBHGFCO_01551	1e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDBHGFCO_01552	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDBHGFCO_01553	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MDBHGFCO_01554	4.33e-36	-	-	-	-	-	-	-	-
MDBHGFCO_01555	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MDBHGFCO_01556	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MDBHGFCO_01557	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDBHGFCO_01558	2.71e-201	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MDBHGFCO_01559	8.42e-102	-	-	-	-	-	-	-	-
MDBHGFCO_01560	1.66e-116	-	-	-	-	-	-	-	-
MDBHGFCO_01561	6.36e-147	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MDBHGFCO_01562	3.51e-184	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MDBHGFCO_01563	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDBHGFCO_01564	3.99e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MDBHGFCO_01565	9.22e-280	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MDBHGFCO_01566	7.15e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MDBHGFCO_01567	2.13e-227	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MDBHGFCO_01569	6.93e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDBHGFCO_01570	2.71e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDBHGFCO_01571	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MDBHGFCO_01572	1.07e-212	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDBHGFCO_01573	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
MDBHGFCO_01574	1.47e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MDBHGFCO_01575	1.15e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MDBHGFCO_01576	9.32e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MDBHGFCO_01577	9.6e-119	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDBHGFCO_01578	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MDBHGFCO_01579	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDBHGFCO_01580	0.0	-	-	-	S	-	-	-	membrane
MDBHGFCO_01581	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDBHGFCO_01582	1.11e-261	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDBHGFCO_01583	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDBHGFCO_01584	1.9e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDBHGFCO_01585	1.01e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MDBHGFCO_01586	1.82e-177	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDBHGFCO_01587	8.53e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MDBHGFCO_01588	1.29e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDBHGFCO_01589	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDBHGFCO_01590	3.11e-169	csrR	-	-	K	-	-	-	response regulator
MDBHGFCO_01591	7.11e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MDBHGFCO_01592	3.98e-277	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MDBHGFCO_01593	1.46e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDBHGFCO_01594	2.26e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MDBHGFCO_01595	1.16e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDBHGFCO_01596	1.12e-268	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MDBHGFCO_01597	1.03e-118	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MDBHGFCO_01598	1.12e-243	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MDBHGFCO_01599	3.54e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDBHGFCO_01600	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MDBHGFCO_01601	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDBHGFCO_01602	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDBHGFCO_01603	8.43e-206	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MDBHGFCO_01604	9.08e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
MDBHGFCO_01605	5.92e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDBHGFCO_01606	5.95e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDBHGFCO_01607	2.85e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDBHGFCO_01608	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDBHGFCO_01609	1.03e-283	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
MDBHGFCO_01610	1.56e-275	-	-	-	EGP	-	-	-	Major Facilitator
MDBHGFCO_01611	6.53e-90	-	-	-	K	-	-	-	Transcriptional regulator
MDBHGFCO_01612	2.25e-15	-	-	-	-	-	-	-	-
MDBHGFCO_01613	1.83e-102	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MDBHGFCO_01614	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MDBHGFCO_01615	2.51e-151	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
MDBHGFCO_01616	1.23e-249	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBHGFCO_01617	8.76e-121	-	-	-	S	-	-	-	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
MDBHGFCO_01618	6.88e-230	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
MDBHGFCO_01619	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
MDBHGFCO_01620	6.8e-168	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MDBHGFCO_01621	6.18e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDBHGFCO_01622	1.01e-69	ytpP	-	-	CO	-	-	-	Thioredoxin
MDBHGFCO_01623	4.5e-90	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_01624	3.87e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDBHGFCO_01625	4.23e-288	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MDBHGFCO_01626	3.26e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_01627	8.29e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MDBHGFCO_01628	2.59e-89	-	-	-	-	-	-	-	-
MDBHGFCO_01629	9.4e-45	-	-	-	S	-	-	-	YtxH-like protein
MDBHGFCO_01630	1.02e-201	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDBHGFCO_01631	1.3e-238	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDBHGFCO_01632	0.0	yhaN	-	-	L	-	-	-	AAA domain
MDBHGFCO_01633	7.05e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MDBHGFCO_01634	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MDBHGFCO_01635	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDBHGFCO_01636	4.68e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MDBHGFCO_01638	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
MDBHGFCO_01639	1.18e-86	-	-	-	-	-	-	-	-
MDBHGFCO_01640	6.16e-121	-	-	-	L	-	-	-	NUDIX domain
MDBHGFCO_01642	3.9e-247	flp	-	-	V	-	-	-	Beta-lactamase
MDBHGFCO_01643	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDBHGFCO_01644	1.43e-152	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDBHGFCO_01645	1.05e-162	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_01646	3.01e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MDBHGFCO_01647	9.18e-208	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
MDBHGFCO_01648	1.8e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MDBHGFCO_01649	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDBHGFCO_01650	5.56e-183	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
MDBHGFCO_01651	3.27e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MDBHGFCO_01652	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
MDBHGFCO_01653	6.37e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
MDBHGFCO_01654	1.19e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
MDBHGFCO_01655	5.03e-122	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
MDBHGFCO_01656	5.26e-194	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MDBHGFCO_01657	3.24e-156	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MDBHGFCO_01658	2.2e-136	-	-	-	S	-	-	-	glycosyl transferase family 2
MDBHGFCO_01659	4.33e-286	-	-	-	M	-	-	-	family 8
MDBHGFCO_01660	1.08e-117	-	-	-	M	-	-	-	family 8
MDBHGFCO_01661	1.38e-109	-	-	-	M	-	-	-	family 8
MDBHGFCO_01663	4.26e-146	-	-	-	UW	-	-	-	Tetratricopeptide repeat
MDBHGFCO_01665	1.1e-236	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MDBHGFCO_01666	1.54e-265	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MDBHGFCO_01667	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDBHGFCO_01668	1.4e-68	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
MDBHGFCO_01669	1.87e-236	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
MDBHGFCO_01670	5.43e-166	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
MDBHGFCO_01671	1.86e-188	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
MDBHGFCO_01672	1.51e-194	-	-	-	S	-	-	-	hydrolase
MDBHGFCO_01674	1.86e-215	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MDBHGFCO_01675	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDBHGFCO_01676	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDBHGFCO_01677	1.29e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDBHGFCO_01678	4.64e-265	camS	-	-	S	-	-	-	sex pheromone
MDBHGFCO_01679	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDBHGFCO_01680	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MDBHGFCO_01681	8.8e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MDBHGFCO_01682	7.24e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MDBHGFCO_01684	1.65e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MDBHGFCO_01685	5.92e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MDBHGFCO_01686	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MDBHGFCO_01687	1.47e-291	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDBHGFCO_01688	4.3e-188	-	-	-	-	-	-	-	-
MDBHGFCO_01689	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MDBHGFCO_01690	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MDBHGFCO_01691	3.56e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDBHGFCO_01692	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDBHGFCO_01693	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDBHGFCO_01694	1.76e-259	-	-	-	M	-	-	-	Glycosyl transferases group 1
MDBHGFCO_01695	7.13e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDBHGFCO_01696	2.31e-87	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
MDBHGFCO_01697	6.31e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MDBHGFCO_01698	4.35e-246	-	-	-	-	-	-	-	-
MDBHGFCO_01699	1.44e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
MDBHGFCO_01702	8.86e-214	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
MDBHGFCO_01703	1.43e-187	-	-	-	K	-	-	-	SIS domain
MDBHGFCO_01705	3.9e-243	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MDBHGFCO_01706	2.61e-78	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
MDBHGFCO_01708	2.22e-159	-	-	-	M	-	-	-	LysM domain protein
MDBHGFCO_01709	6.25e-173	-	-	-	M	-	-	-	LysM domain protein
MDBHGFCO_01710	1.76e-173	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MDBHGFCO_01711	7.55e-80	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MDBHGFCO_01712	1.7e-122	-	-	-	K	-	-	-	acetyltransferase
MDBHGFCO_01713	6.6e-32	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_01714	9.32e-85	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDBHGFCO_01716	1.35e-204	yvgN	-	-	C	-	-	-	Aldo keto reductase
MDBHGFCO_01717	6.87e-312	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MDBHGFCO_01718	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MDBHGFCO_01719	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
MDBHGFCO_01720	0.0	-	-	-	S	-	-	-	TerB-C domain
MDBHGFCO_01721	9.96e-131	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MDBHGFCO_01722	2.33e-92	-	-	-	-	-	-	-	-
MDBHGFCO_01723	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MDBHGFCO_01724	4.31e-297	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MDBHGFCO_01741	1.09e-79	-	-	-	-	-	-	-	-
MDBHGFCO_01753	1.33e-280	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
MDBHGFCO_01754	7.12e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MDBHGFCO_01755	1.82e-231	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDBHGFCO_01756	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDBHGFCO_01757	1.34e-190	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MDBHGFCO_01760	3.81e-34	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides