ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NEHAAAKM_00001 1.13e-48 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NEHAAAKM_00002 5.14e-268 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEHAAAKM_00003 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEHAAAKM_00004 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEHAAAKM_00005 1.93e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NEHAAAKM_00006 7.46e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEHAAAKM_00007 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEHAAAKM_00008 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NEHAAAKM_00009 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEHAAAKM_00010 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NEHAAAKM_00011 1.94e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
NEHAAAKM_00012 2.36e-217 degV1 - - S - - - DegV family
NEHAAAKM_00013 1.07e-171 - - - V - - - ABC transporter transmembrane region
NEHAAAKM_00014 5.79e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NEHAAAKM_00015 3.81e-18 - - - S - - - CsbD-like
NEHAAAKM_00016 2.26e-31 - - - S - - - Transglycosylase associated protein
NEHAAAKM_00017 5.32e-285 - - - I - - - Protein of unknown function (DUF2974)
NEHAAAKM_00018 4.38e-150 - - - S ko:K07507 - ko00000,ko02000 MgtC family
NEHAAAKM_00021 7.2e-84 - - - - - - - -
NEHAAAKM_00022 7.06e-110 - - - - - - - -
NEHAAAKM_00023 1.36e-171 - - - D - - - Ftsk spoiiie family protein
NEHAAAKM_00024 2.22e-178 - - - S - - - Replication initiation factor
NEHAAAKM_00025 1.33e-72 - - - - - - - -
NEHAAAKM_00026 4.04e-36 - - - - - - - -
NEHAAAKM_00027 3.5e-280 - - - L - - - Belongs to the 'phage' integrase family
NEHAAAKM_00029 9.75e-80 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEHAAAKM_00030 8.25e-65 - - - V ko:K01990,ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NEHAAAKM_00032 6.56e-86 sagB - - C - - - Nitroreductase family
NEHAAAKM_00034 1.28e-162 sagD - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
NEHAAAKM_00035 3.58e-05 - - - S - - - Bacteriocin helveticin-J
NEHAAAKM_00036 3.56e-85 - - - S - - - SLAP domain
NEHAAAKM_00037 8.58e-60 - - - - - - - -
NEHAAAKM_00038 8.64e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_00039 4.76e-168 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEHAAAKM_00040 3.35e-223 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NEHAAAKM_00041 7.75e-170 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEHAAAKM_00042 7.93e-63 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEHAAAKM_00043 5.49e-97 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEHAAAKM_00044 9.52e-205 yvgN - - C - - - Aldo keto reductase
NEHAAAKM_00045 0.0 fusA1 - - J - - - elongation factor G
NEHAAAKM_00046 3.16e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
NEHAAAKM_00047 2.54e-112 - - - EGP - - - Major Facilitator Superfamily
NEHAAAKM_00049 4.37e-47 - - - EGP - - - Major Facilitator Superfamily
NEHAAAKM_00051 5.31e-33 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEHAAAKM_00052 2.27e-245 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHAAAKM_00053 1.44e-07 - - - S - - - YSIRK type signal peptide
NEHAAAKM_00055 1.2e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NEHAAAKM_00056 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
NEHAAAKM_00057 0.0 - - - L - - - Helicase C-terminal domain protein
NEHAAAKM_00058 6.72e-261 pbpX - - V - - - Beta-lactamase
NEHAAAKM_00059 1.05e-289 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NEHAAAKM_00060 4.19e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NEHAAAKM_00062 3.11e-13 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEHAAAKM_00063 1.38e-107 - - - J - - - FR47-like protein
NEHAAAKM_00064 3.37e-50 - - - S - - - Cytochrome B5
NEHAAAKM_00065 3.92e-215 arbZ - - I - - - Phosphate acyltransferases
NEHAAAKM_00066 5.48e-235 - - - M - - - Glycosyl transferase family 8
NEHAAAKM_00067 1.91e-236 - - - M - - - Glycosyl transferase family 8
NEHAAAKM_00068 7.23e-201 arbx - - M - - - Glycosyl transferase family 8
NEHAAAKM_00069 4.19e-192 - - - I - - - Acyl-transferase
NEHAAAKM_00071 1.09e-46 - - - - - - - -
NEHAAAKM_00073 3.98e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NEHAAAKM_00074 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEHAAAKM_00075 0.0 yycH - - S - - - YycH protein
NEHAAAKM_00076 7.44e-192 yycI - - S - - - YycH protein
NEHAAAKM_00077 1.19e-188 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NEHAAAKM_00078 3.17e-224 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NEHAAAKM_00079 8.64e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEHAAAKM_00080 1.93e-32 - - - G - - - Peptidase_C39 like family
NEHAAAKM_00081 2.16e-207 - - - M - - - NlpC/P60 family
NEHAAAKM_00082 6.67e-115 - - - G - - - Peptidase_C39 like family
NEHAAAKM_00083 1.09e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEHAAAKM_00084 1.19e-114 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NEHAAAKM_00085 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_00086 1.05e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
NEHAAAKM_00087 1.16e-207 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NEHAAAKM_00088 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
NEHAAAKM_00089 8.43e-243 ysdE - - P - - - Citrate transporter
NEHAAAKM_00090 3.34e-92 - - - S - - - Iron-sulphur cluster biosynthesis
NEHAAAKM_00091 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
NEHAAAKM_00092 9.69e-25 - - - - - - - -
NEHAAAKM_00093 1.34e-09 - - - S - - - Uncharacterised protein family (UPF0236)
NEHAAAKM_00094 4.75e-239 - - - M - - - Glycosyl transferase
NEHAAAKM_00095 3.67e-225 - - - G - - - Glycosyl hydrolases family 8
NEHAAAKM_00096 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NEHAAAKM_00097 2.42e-204 - - - L - - - HNH nucleases
NEHAAAKM_00098 1.4e-191 yhaH - - S - - - Protein of unknown function (DUF805)
NEHAAAKM_00099 2.89e-173 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_00100 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHAAAKM_00101 1.41e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NEHAAAKM_00102 7.63e-85 yeaO - - S - - - Protein of unknown function, DUF488
NEHAAAKM_00103 1.14e-164 terC - - P - - - Integral membrane protein TerC family
NEHAAAKM_00104 1.25e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
NEHAAAKM_00105 1.24e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
NEHAAAKM_00106 2.29e-112 - - - - - - - -
NEHAAAKM_00107 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEHAAAKM_00108 1.24e-232 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHAAAKM_00109 5.07e-190 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEHAAAKM_00110 9.18e-187 - - - S - - - Protein of unknown function (DUF1002)
NEHAAAKM_00111 2.62e-199 epsV - - S - - - glycosyl transferase family 2
NEHAAAKM_00112 5.29e-164 - - - S - - - Alpha/beta hydrolase family
NEHAAAKM_00113 2.32e-47 - - - - - - - -
NEHAAAKM_00114 1.76e-233 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEHAAAKM_00115 8.37e-161 - - - K - - - Bacterial regulatory proteins, tetR family
NEHAAAKM_00116 1.11e-177 - - - - - - - -
NEHAAAKM_00117 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEHAAAKM_00118 1.01e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_00119 7.36e-291 - - - S - - - Cysteine-rich secretory protein family
NEHAAAKM_00120 2.43e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NEHAAAKM_00121 2.45e-164 - - - - - - - -
NEHAAAKM_00122 6.89e-258 yibE - - S - - - overlaps another CDS with the same product name
NEHAAAKM_00123 2.23e-166 yibF - - S - - - overlaps another CDS with the same product name
NEHAAAKM_00124 4.67e-200 - - - I - - - alpha/beta hydrolase fold
NEHAAAKM_00125 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
NEHAAAKM_00126 3.75e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEHAAAKM_00128 1.14e-115 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
NEHAAAKM_00129 4.4e-112 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHAAAKM_00130 3.56e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEHAAAKM_00131 2.65e-108 usp5 - - T - - - universal stress protein
NEHAAAKM_00133 1.78e-212 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
NEHAAAKM_00134 6.34e-180 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NEHAAAKM_00135 1.91e-168 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHAAAKM_00136 1.29e-190 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHAAAKM_00137 7.05e-103 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
NEHAAAKM_00138 1.87e-220 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
NEHAAAKM_00139 5.61e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NEHAAAKM_00140 5.18e-109 - - - - - - - -
NEHAAAKM_00141 0.0 - - - S - - - Calcineurin-like phosphoesterase
NEHAAAKM_00142 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NEHAAAKM_00143 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NEHAAAKM_00144 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NEHAAAKM_00145 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEHAAAKM_00146 2.18e-132 yitW - - S - - - Iron-sulfur cluster assembly protein
NEHAAAKM_00147 2.19e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
NEHAAAKM_00148 5.67e-278 yqjV - - EGP - - - Major Facilitator Superfamily
NEHAAAKM_00149 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NEHAAAKM_00150 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEHAAAKM_00151 6.55e-97 - - - - - - - -
NEHAAAKM_00152 3.75e-48 - - - S - - - PFAM Archaeal ATPase
NEHAAAKM_00154 4.53e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NEHAAAKM_00155 3.61e-60 - - - - - - - -
NEHAAAKM_00156 8.28e-28 - - - - - - - -
NEHAAAKM_00157 1.21e-40 - - - - - - - -
NEHAAAKM_00158 1.05e-54 - - - S - - - Protein of unknown function (DUF2922)
NEHAAAKM_00159 1.33e-133 - - - S - - - SLAP domain
NEHAAAKM_00160 6.87e-27 - - - S - - - PD-(D/E)XK nuclease family transposase
NEHAAAKM_00162 2.6e-188 - - - S - - - PD-(D/E)XK nuclease family transposase
NEHAAAKM_00164 8.49e-100 - - - K - - - DNA-templated transcription, initiation
NEHAAAKM_00165 2.85e-54 - - - - - - - -
NEHAAAKM_00167 5.21e-162 - - - S - - - SLAP domain
NEHAAAKM_00169 1.47e-286 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEHAAAKM_00170 8.93e-233 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
NEHAAAKM_00171 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NEHAAAKM_00172 2.47e-138 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEHAAAKM_00173 1.68e-207 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NEHAAAKM_00174 1.98e-168 - - - - - - - -
NEHAAAKM_00175 1.72e-149 - - - - - - - -
NEHAAAKM_00176 4.51e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEHAAAKM_00177 5.18e-128 - - - G - - - Aldose 1-epimerase
NEHAAAKM_00178 2.92e-258 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEHAAAKM_00179 1.03e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEHAAAKM_00180 0.0 XK27_08315 - - M - - - Sulfatase
NEHAAAKM_00181 0.0 - - - S - - - Fibronectin type III domain
NEHAAAKM_00182 7.03e-307 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEHAAAKM_00183 9.39e-71 - - - - - - - -
NEHAAAKM_00185 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NEHAAAKM_00186 1.77e-157 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHAAAKM_00187 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHAAAKM_00188 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHAAAKM_00189 1.08e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEHAAAKM_00190 1.34e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHAAAKM_00191 6.71e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHAAAKM_00192 6.08e-253 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHAAAKM_00193 6.54e-222 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHAAAKM_00194 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NEHAAAKM_00195 8.35e-94 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEHAAAKM_00196 2.02e-38 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEHAAAKM_00197 1.67e-143 - - - - - - - -
NEHAAAKM_00199 1.66e-143 - - - E - - - Belongs to the SOS response-associated peptidase family
NEHAAAKM_00200 4.07e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEHAAAKM_00201 4.29e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
NEHAAAKM_00202 4.57e-135 - - - S ko:K06872 - ko00000 TPM domain
NEHAAAKM_00203 1.28e-172 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
NEHAAAKM_00204 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
NEHAAAKM_00205 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEHAAAKM_00206 2.72e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NEHAAAKM_00207 5.17e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NEHAAAKM_00208 2.56e-193 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEHAAAKM_00209 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
NEHAAAKM_00210 2.91e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NEHAAAKM_00211 3.12e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEHAAAKM_00212 5.52e-113 - - - - - - - -
NEHAAAKM_00213 0.0 - - - S - - - SLAP domain
NEHAAAKM_00214 5.4e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEHAAAKM_00215 2.45e-47 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEHAAAKM_00216 1.37e-219 - - - GK - - - ROK family
NEHAAAKM_00217 2.53e-56 - - - - - - - -
NEHAAAKM_00218 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHAAAKM_00219 1.75e-89 - - - S - - - Domain of unknown function (DUF1934)
NEHAAAKM_00220 2.38e-88 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NEHAAAKM_00221 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEHAAAKM_00222 1.89e-312 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEHAAAKM_00223 7.28e-97 - - - K - - - acetyltransferase
NEHAAAKM_00224 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEHAAAKM_00225 2.73e-201 msmR - - K - - - AraC-like ligand binding domain
NEHAAAKM_00226 1.08e-289 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NEHAAAKM_00227 7.92e-135 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEHAAAKM_00228 1.1e-54 - - - K - - - Helix-turn-helix
NEHAAAKM_00229 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NEHAAAKM_00231 1.89e-129 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NEHAAAKM_00232 6.79e-270 - - - M - - - Rib/alpha-like repeat
NEHAAAKM_00233 2.24e-291 - - - M - - - Rib/alpha-like repeat
NEHAAAKM_00234 5.22e-05 - - - - - - - -
NEHAAAKM_00235 1.11e-95 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
NEHAAAKM_00236 3.74e-125 - - - - - - - -
NEHAAAKM_00237 8.88e-178 - - - P - - - Voltage gated chloride channel
NEHAAAKM_00238 3.44e-238 - - - C - - - FMN-dependent dehydrogenase
NEHAAAKM_00239 8.68e-69 - - - - - - - -
NEHAAAKM_00240 1.17e-56 - - - - - - - -
NEHAAAKM_00241 1.33e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEHAAAKM_00242 0.0 - - - E - - - amino acid
NEHAAAKM_00243 1.64e-200 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEHAAAKM_00244 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
NEHAAAKM_00245 1.07e-52 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NEHAAAKM_00246 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEHAAAKM_00247 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NEHAAAKM_00248 9.39e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEHAAAKM_00249 1.62e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEHAAAKM_00250 1.23e-166 - - - S - - - (CBS) domain
NEHAAAKM_00251 2.93e-234 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NEHAAAKM_00252 1.89e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEHAAAKM_00253 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEHAAAKM_00254 7.32e-46 yabO - - J - - - S4 domain protein
NEHAAAKM_00255 7.52e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NEHAAAKM_00256 1.61e-81 - - - J ko:K07571 - ko00000 S1 RNA binding domain
NEHAAAKM_00257 2.75e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEHAAAKM_00258 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEHAAAKM_00259 3.91e-214 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NEHAAAKM_00260 2.77e-248 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHAAAKM_00261 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NEHAAAKM_00262 2.84e-108 - - - K - - - FR47-like protein
NEHAAAKM_00267 5.95e-92 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NEHAAAKM_00268 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEHAAAKM_00269 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHAAAKM_00270 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHAAAKM_00271 7.71e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NEHAAAKM_00272 1.47e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEHAAAKM_00273 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEHAAAKM_00274 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEHAAAKM_00275 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NEHAAAKM_00276 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEHAAAKM_00277 4.68e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NEHAAAKM_00278 1.14e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEHAAAKM_00279 3.3e-197 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEHAAAKM_00280 1.14e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEHAAAKM_00281 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEHAAAKM_00282 8.7e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEHAAAKM_00283 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEHAAAKM_00284 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NEHAAAKM_00285 1.56e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEHAAAKM_00286 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEHAAAKM_00287 3.03e-44 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEHAAAKM_00288 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEHAAAKM_00289 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEHAAAKM_00290 7.94e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEHAAAKM_00291 7.18e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEHAAAKM_00292 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEHAAAKM_00293 3.73e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEHAAAKM_00294 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NEHAAAKM_00295 2.86e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEHAAAKM_00296 3.59e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEHAAAKM_00297 3.7e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEHAAAKM_00298 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEHAAAKM_00299 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NEHAAAKM_00300 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEHAAAKM_00301 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEHAAAKM_00302 3.62e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHAAAKM_00303 2.23e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NEHAAAKM_00304 5.91e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHAAAKM_00305 1.58e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHAAAKM_00306 3.61e-174 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHAAAKM_00307 5.69e-190 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEHAAAKM_00308 3.22e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEHAAAKM_00309 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NEHAAAKM_00310 1.44e-234 - - - L - - - Phage integrase family
NEHAAAKM_00311 4.57e-135 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NEHAAAKM_00312 1.56e-152 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEHAAAKM_00313 2.02e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
NEHAAAKM_00314 3.16e-160 - - - G - - - Belongs to the phosphoglycerate mutase family
NEHAAAKM_00315 8.43e-206 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NEHAAAKM_00316 2.42e-33 - - - - - - - -
NEHAAAKM_00317 9.82e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEHAAAKM_00318 2.32e-234 - - - S - - - AAA domain
NEHAAAKM_00319 8.69e-66 - - - - - - - -
NEHAAAKM_00320 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEHAAAKM_00321 1.11e-69 - - - - - - - -
NEHAAAKM_00322 5.22e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NEHAAAKM_00323 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEHAAAKM_00324 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEHAAAKM_00325 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEHAAAKM_00326 2.45e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NEHAAAKM_00327 2.69e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEHAAAKM_00328 1.55e-122 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NEHAAAKM_00329 1.19e-45 - - - - - - - -
NEHAAAKM_00330 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NEHAAAKM_00331 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEHAAAKM_00332 3.73e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEHAAAKM_00333 5e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NEHAAAKM_00334 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEHAAAKM_00335 1.05e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEHAAAKM_00336 5.48e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NEHAAAKM_00337 1.13e-210 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NEHAAAKM_00338 2.48e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NEHAAAKM_00339 5.24e-187 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHAAAKM_00340 3.83e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHAAAKM_00341 2.89e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NEHAAAKM_00343 3.72e-111 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEHAAAKM_00344 1.61e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEHAAAKM_00345 9.32e-189 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
NEHAAAKM_00346 5.31e-149 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NEHAAAKM_00347 6.15e-36 - - - - - - - -
NEHAAAKM_00348 1.08e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEHAAAKM_00349 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEHAAAKM_00350 1.12e-136 - - - M - - - family 8
NEHAAAKM_00351 1.15e-47 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
NEHAAAKM_00352 6.31e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NEHAAAKM_00353 9.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEHAAAKM_00354 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
NEHAAAKM_00355 1.15e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEHAAAKM_00356 1.58e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
NEHAAAKM_00357 8.4e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEHAAAKM_00358 1.4e-80 yabA - - L - - - Involved in initiation control of chromosome replication
NEHAAAKM_00359 3.05e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEHAAAKM_00360 4.27e-167 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NEHAAAKM_00361 8.72e-111 - - - S - - - ECF transporter, substrate-specific component
NEHAAAKM_00362 3.69e-171 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NEHAAAKM_00363 3.93e-125 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NEHAAAKM_00364 3.35e-246 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEHAAAKM_00365 1.28e-311 - - - L ko:K07484 - ko00000 Transposase IS66 family
NEHAAAKM_00366 5.51e-46 - - - S - - - Transposase C of IS166 homeodomain
NEHAAAKM_00367 4.01e-84 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NEHAAAKM_00368 9.48e-31 - - - - - - - -
NEHAAAKM_00369 3.06e-53 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NEHAAAKM_00370 6.43e-230 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NEHAAAKM_00371 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NEHAAAKM_00372 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NEHAAAKM_00373 8.74e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEHAAAKM_00374 2.14e-234 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEHAAAKM_00375 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NEHAAAKM_00376 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHAAAKM_00377 2.14e-231 - - - M - - - CHAP domain
NEHAAAKM_00378 2.79e-102 - - - - - - - -
NEHAAAKM_00379 1.06e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEHAAAKM_00380 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEHAAAKM_00381 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEHAAAKM_00382 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEHAAAKM_00383 3.89e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEHAAAKM_00384 1.39e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEHAAAKM_00385 7.58e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NEHAAAKM_00386 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEHAAAKM_00387 6.15e-268 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEHAAAKM_00388 3.16e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NEHAAAKM_00389 1.26e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NEHAAAKM_00390 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEHAAAKM_00391 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
NEHAAAKM_00392 9.37e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEHAAAKM_00393 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
NEHAAAKM_00394 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEHAAAKM_00395 5.37e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NEHAAAKM_00396 2.34e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEHAAAKM_00397 5.62e-95 yslB - - S - - - Protein of unknown function (DUF2507)
NEHAAAKM_00398 4.13e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NEHAAAKM_00399 8.12e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEHAAAKM_00400 1.55e-29 - - - - - - - -
NEHAAAKM_00401 5.53e-147 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NEHAAAKM_00402 1.03e-76 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEHAAAKM_00403 4.28e-187 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NEHAAAKM_00404 2.96e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NEHAAAKM_00405 3.09e-71 - - - - - - - -
NEHAAAKM_00406 1.6e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEHAAAKM_00407 1.23e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NEHAAAKM_00408 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NEHAAAKM_00409 9.89e-74 - - - - - - - -
NEHAAAKM_00410 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NEHAAAKM_00411 4.25e-119 yutD - - S - - - Protein of unknown function (DUF1027)
NEHAAAKM_00412 6.38e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NEHAAAKM_00413 2.15e-137 - - - S - - - Protein of unknown function (DUF1461)
NEHAAAKM_00414 6.9e-150 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NEHAAAKM_00415 1.76e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NEHAAAKM_00443 1.72e-286 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
NEHAAAKM_00444 3.68e-256 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NEHAAAKM_00445 1.53e-223 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEHAAAKM_00446 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEHAAAKM_00447 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NEHAAAKM_00448 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEHAAAKM_00449 1.58e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEHAAAKM_00452 5.31e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEHAAAKM_00455 7.29e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEHAAAKM_00456 0.0 mdr - - EGP - - - Major Facilitator
NEHAAAKM_00458 1.92e-102 - - - K - - - Helix-turn-helix domain, rpiR family
NEHAAAKM_00459 3.39e-154 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEHAAAKM_00460 1.32e-151 - - - S - - - Putative esterase
NEHAAAKM_00461 1.81e-270 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHAAAKM_00462 7.66e-248 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEHAAAKM_00463 3.75e-168 - - - K - - - rpiR family
NEHAAAKM_00464 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NEHAAAKM_00465 9.83e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NEHAAAKM_00466 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NEHAAAKM_00467 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NEHAAAKM_00468 1.76e-165 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NEHAAAKM_00469 3.38e-227 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEHAAAKM_00470 1.03e-206 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NEHAAAKM_00471 3.01e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NEHAAAKM_00472 1.41e-51 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHAAAKM_00473 9.32e-109 - - - S - - - PD-(D/E)XK nuclease family transposase
NEHAAAKM_00474 6.75e-216 - - - K - - - LysR substrate binding domain
NEHAAAKM_00475 1.39e-156 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NEHAAAKM_00476 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NEHAAAKM_00477 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEHAAAKM_00478 3.11e-256 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHAAAKM_00479 4.84e-42 - - - - - - - -
NEHAAAKM_00480 9.14e-187 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NEHAAAKM_00481 8.73e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NEHAAAKM_00482 8.63e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NEHAAAKM_00483 4.66e-179 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHAAAKM_00484 6.07e-138 - - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NEHAAAKM_00485 2.69e-156 phoB - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NEHAAAKM_00486 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEHAAAKM_00487 3.54e-300 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
NEHAAAKM_00488 1.59e-61 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NEHAAAKM_00490 9.64e-307 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NEHAAAKM_00491 2.23e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEHAAAKM_00492 5.6e-129 - - - M - - - ErfK YbiS YcfS YnhG
NEHAAAKM_00493 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NEHAAAKM_00494 6.03e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NEHAAAKM_00495 8.08e-108 - - - S - - - PFAM Archaeal ATPase
NEHAAAKM_00496 1.32e-105 - - - S - - - PFAM Archaeal ATPase
NEHAAAKM_00497 7.02e-36 - - - - - - - -
NEHAAAKM_00498 1.01e-98 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
NEHAAAKM_00499 1.86e-91 - - - S ko:K07133 - ko00000 cog cog1373
NEHAAAKM_00500 1.28e-226 - - - S - - - PFAM Archaeal ATPase
NEHAAAKM_00501 4.77e-248 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NEHAAAKM_00502 4.95e-164 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NEHAAAKM_00503 2.74e-06 - - - S - - - PFAM Archaeal ATPase
NEHAAAKM_00504 5.46e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEHAAAKM_00505 7.62e-134 - - - G - - - Phosphoglycerate mutase family
NEHAAAKM_00506 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NEHAAAKM_00507 1.21e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NEHAAAKM_00508 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NEHAAAKM_00509 8.43e-73 yheA - - S - - - Belongs to the UPF0342 family
NEHAAAKM_00510 4.24e-289 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
NEHAAAKM_00511 0.0 yhaN - - L - - - AAA domain
NEHAAAKM_00512 4.53e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHAAAKM_00514 9.67e-33 - - - S - - - Domain of unknown function DUF1829
NEHAAAKM_00515 0.0 - - - - - - - -
NEHAAAKM_00516 5.74e-96 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
NEHAAAKM_00517 3.12e-196 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEHAAAKM_00518 1.2e-41 - - - - - - - -
NEHAAAKM_00519 1.61e-101 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
NEHAAAKM_00520 3.67e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_00521 1.63e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NEHAAAKM_00522 2.16e-163 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEHAAAKM_00524 1.35e-71 ytpP - - CO - - - Thioredoxin
NEHAAAKM_00525 1.28e-156 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEHAAAKM_00526 2.59e-313 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NEHAAAKM_00527 4.65e-278 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NEHAAAKM_00528 2.04e-226 - - - S - - - SLAP domain
NEHAAAKM_00529 0.0 - - - M - - - Peptidase family M1 domain
NEHAAAKM_00530 2.43e-239 - - - S - - - Bacteriocin helveticin-J
NEHAAAKM_00531 1.33e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NEHAAAKM_00532 2.53e-139 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NEHAAAKM_00533 1.98e-35 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NEHAAAKM_00534 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEHAAAKM_00535 7.81e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NEHAAAKM_00536 2.16e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEHAAAKM_00537 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEHAAAKM_00538 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
NEHAAAKM_00539 1.31e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NEHAAAKM_00540 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEHAAAKM_00541 5.59e-98 - - - - - - - -
NEHAAAKM_00542 4.78e-261 - - - S - - - Domain of unknown function (DUF389)
NEHAAAKM_00543 1.53e-122 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_00544 6.49e-137 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_00547 8.95e-70 - - - K - - - LytTr DNA-binding domain
NEHAAAKM_00548 9.29e-51 - - - S - - - Protein of unknown function (DUF3021)
NEHAAAKM_00549 1.08e-217 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEHAAAKM_00550 8.9e-30 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
NEHAAAKM_00551 1.1e-128 - - - E ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHAAAKM_00552 6.18e-123 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NEHAAAKM_00553 1.07e-93 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEHAAAKM_00554 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NEHAAAKM_00555 8.69e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEHAAAKM_00556 1.25e-192 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NEHAAAKM_00557 3.01e-255 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEHAAAKM_00558 6.85e-109 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NEHAAAKM_00559 5.03e-256 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NEHAAAKM_00560 1.77e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEHAAAKM_00561 9.22e-141 yqeK - - H - - - Hydrolase, HD family
NEHAAAKM_00562 5.09e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEHAAAKM_00563 4.63e-275 ylbM - - S - - - Belongs to the UPF0348 family
NEHAAAKM_00564 2.19e-125 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NEHAAAKM_00565 3.52e-163 csrR - - K - - - response regulator
NEHAAAKM_00566 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEHAAAKM_00567 9.04e-162 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHAAAKM_00568 7.24e-284 - - - S - - - SLAP domain
NEHAAAKM_00569 2.42e-69 - - - S - - - Abi-like protein
NEHAAAKM_00570 2.08e-95 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
NEHAAAKM_00571 2.43e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEHAAAKM_00572 5.58e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NEHAAAKM_00573 3.23e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEHAAAKM_00574 4.87e-81 yodB - - K - - - Transcriptional regulator, HxlR family
NEHAAAKM_00576 1.8e-142 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
NEHAAAKM_00577 4.11e-150 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
NEHAAAKM_00578 1.89e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_00579 1.02e-67 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NEHAAAKM_00580 8.08e-117 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NEHAAAKM_00581 2.9e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEHAAAKM_00582 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEHAAAKM_00583 1.72e-92 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEHAAAKM_00584 8.21e-215 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
NEHAAAKM_00585 5.5e-203 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEHAAAKM_00586 1.8e-34 - - - - - - - -
NEHAAAKM_00587 0.0 sufI - - Q - - - Multicopper oxidase
NEHAAAKM_00588 1.76e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEHAAAKM_00589 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHAAAKM_00590 2.77e-292 - - - Q - - - Imidazolonepropionase and related amidohydrolases
NEHAAAKM_00591 5.84e-312 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
NEHAAAKM_00592 1.3e-175 - - - S - - - Protein of unknown function (DUF3100)
NEHAAAKM_00593 2.04e-60 - - - S - - - An automated process has identified a potential problem with this gene model
NEHAAAKM_00594 4.34e-64 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NEHAAAKM_00595 1.29e-164 - - - S - - - SLAP domain
NEHAAAKM_00596 6.09e-121 - - - - - - - -
NEHAAAKM_00598 7.04e-159 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
NEHAAAKM_00599 2.07e-203 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NEHAAAKM_00600 1.55e-201 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHAAAKM_00601 1.49e-178 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NEHAAAKM_00602 2.22e-60 hupB2 - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEHAAAKM_00603 2.74e-69 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
NEHAAAKM_00604 9.43e-52 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
NEHAAAKM_00605 7.04e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
NEHAAAKM_00606 0.0 - - - S - - - membrane
NEHAAAKM_00607 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NEHAAAKM_00608 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NEHAAAKM_00609 7.92e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NEHAAAKM_00610 3.25e-154 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
NEHAAAKM_00611 1e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NEHAAAKM_00612 4.95e-89 yqhL - - P - - - Rhodanese-like protein
NEHAAAKM_00613 3.84e-216 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEHAAAKM_00614 2.05e-286 ynbB - - P - - - aluminum resistance
NEHAAAKM_00615 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NEHAAAKM_00616 2.37e-219 - - - - - - - -
NEHAAAKM_00617 2.09e-205 - - - - - - - -
NEHAAAKM_00621 6.78e-47 - - - - - - - -
NEHAAAKM_00622 1.44e-161 - - - S - - - interspecies interaction between organisms
NEHAAAKM_00623 1.28e-09 - - - S - - - PFAM HicB family
NEHAAAKM_00624 2.86e-13 - - - K ko:K15773 - ko00000,ko02048,ko03000 peptidyl-tyrosine sulfation
NEHAAAKM_00625 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHAAAKM_00626 1.57e-84 - - - K - - - Helix-turn-helix domain, rpiR family
NEHAAAKM_00627 2.65e-154 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NEHAAAKM_00628 1.03e-112 nanK - - GK - - - ROK family
NEHAAAKM_00629 3.74e-70 - - - G - - - Xylose isomerase domain protein TIM barrel
NEHAAAKM_00630 1.48e-166 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEHAAAKM_00631 6.48e-279 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEHAAAKM_00632 1.4e-74 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NEHAAAKM_00633 4.42e-45 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NEHAAAKM_00634 6.9e-141 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NEHAAAKM_00635 2.58e-13 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEHAAAKM_00636 1.59e-108 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEHAAAKM_00637 4.05e-242 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
NEHAAAKM_00638 5.55e-137 - - - K - - - Transcriptional regulator, AbiEi antitoxin
NEHAAAKM_00639 2.44e-210 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
NEHAAAKM_00640 2.84e-240 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NEHAAAKM_00641 5.06e-184 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
NEHAAAKM_00642 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEHAAAKM_00643 1.48e-210 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEHAAAKM_00644 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NEHAAAKM_00645 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NEHAAAKM_00646 4.16e-280 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NEHAAAKM_00647 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NEHAAAKM_00648 1.6e-251 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NEHAAAKM_00649 2.14e-48 - - - - - - - -
NEHAAAKM_00650 6.89e-93 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
NEHAAAKM_00651 4.65e-40 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEHAAAKM_00652 4e-31 dltr - - K - - - response regulator
NEHAAAKM_00653 3e-290 sptS - - T - - - Histidine kinase
NEHAAAKM_00654 1.36e-266 - - - EGP - - - Major Facilitator Superfamily
NEHAAAKM_00655 2.65e-89 - - - O - - - OsmC-like protein
NEHAAAKM_00656 1.92e-113 yhaH - - S - - - Protein of unknown function (DUF805)
NEHAAAKM_00657 5.87e-110 - - - - - - - -
NEHAAAKM_00658 0.0 - - - - - - - -
NEHAAAKM_00659 2.65e-107 - - - S - - - Fic/DOC family
NEHAAAKM_00660 0.0 potE - - E - - - Amino Acid
NEHAAAKM_00661 2.44e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHAAAKM_00662 1.43e-309 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NEHAAAKM_00663 7.68e-63 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NEHAAAKM_00664 5.01e-150 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NEHAAAKM_00665 6.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
NEHAAAKM_00666 3.15e-198 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NEHAAAKM_00667 9.46e-159 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NEHAAAKM_00668 3.23e-59 - - - - - - - -
NEHAAAKM_00669 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NEHAAAKM_00670 1.43e-93 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NEHAAAKM_00671 3.76e-311 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NEHAAAKM_00672 4.14e-113 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
NEHAAAKM_00674 5.32e-42 - - - - ko:K18829 - ko00000,ko02048 -
NEHAAAKM_00675 4.02e-91 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
NEHAAAKM_00676 9e-132 - - - L - - - Integrase
NEHAAAKM_00677 5.22e-45 ykzG - - S - - - Belongs to the UPF0356 family
NEHAAAKM_00678 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEHAAAKM_00679 4.37e-132 - - - GM - - - NmrA-like family
NEHAAAKM_00680 5.5e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEHAAAKM_00681 1.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NEHAAAKM_00682 8.81e-212 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEHAAAKM_00683 2.9e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEHAAAKM_00684 9.05e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NEHAAAKM_00685 8.31e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEHAAAKM_00686 4.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NEHAAAKM_00687 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEHAAAKM_00688 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NEHAAAKM_00689 6.79e-190 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NEHAAAKM_00690 8.74e-62 - - - - - - - -
NEHAAAKM_00691 2.88e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NEHAAAKM_00692 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NEHAAAKM_00693 1.02e-29 - - - S - - - Alpha beta hydrolase
NEHAAAKM_00694 2.48e-80 - - - S - - - Alpha beta hydrolase
NEHAAAKM_00695 8.51e-50 - - - - - - - -
NEHAAAKM_00696 4.3e-66 - - - - - - - -
NEHAAAKM_00697 1.14e-189 supH - - S - - - haloacid dehalogenase-like hydrolase
NEHAAAKM_00698 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NEHAAAKM_00699 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NEHAAAKM_00700 1.82e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NEHAAAKM_00701 1.23e-227 lipA - - I - - - Carboxylesterase family
NEHAAAKM_00703 1.16e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEHAAAKM_00704 1.08e-173 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
NEHAAAKM_00705 0.0 - - - S - - - Predicted membrane protein (DUF2207)
NEHAAAKM_00706 2.07e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NEHAAAKM_00708 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NEHAAAKM_00709 5.24e-194 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEHAAAKM_00710 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NEHAAAKM_00711 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NEHAAAKM_00712 2.14e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEHAAAKM_00713 2.11e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEHAAAKM_00714 7.98e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NEHAAAKM_00715 2.78e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEHAAAKM_00716 7.19e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEHAAAKM_00717 1.97e-248 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEHAAAKM_00718 1.53e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEHAAAKM_00719 6.44e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEHAAAKM_00720 7.22e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NEHAAAKM_00721 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NEHAAAKM_00722 2.19e-100 - - - S - - - ASCH
NEHAAAKM_00723 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NEHAAAKM_00724 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEHAAAKM_00725 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEHAAAKM_00726 1.27e-219 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEHAAAKM_00727 7.82e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEHAAAKM_00728 3.28e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NEHAAAKM_00729 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NEHAAAKM_00730 1.71e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEHAAAKM_00731 7.49e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NEHAAAKM_00732 1.1e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NEHAAAKM_00733 2.29e-41 - - - - - - - -
NEHAAAKM_00734 8.76e-146 int3 - - L - - - Belongs to the 'phage' integrase family
NEHAAAKM_00736 6.12e-166 - - - S - - - Phage Terminase
NEHAAAKM_00738 2.23e-169 - - - S - - - Phage portal protein
NEHAAAKM_00739 4.37e-110 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NEHAAAKM_00740 5.87e-67 - - - S - - - Phage capsid family
NEHAAAKM_00748 4.83e-131 - - - L - - - Phage tail tape measure protein TP901
NEHAAAKM_00750 5.6e-158 - - - S - - - Phage minor structural protein
NEHAAAKM_00758 6.5e-51 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NEHAAAKM_00759 8.02e-127 - - - M - - - hydrolase, family 25
NEHAAAKM_00761 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NEHAAAKM_00762 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
NEHAAAKM_00763 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NEHAAAKM_00764 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEHAAAKM_00765 3.69e-233 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEHAAAKM_00766 7.32e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEHAAAKM_00767 1.21e-245 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHAAAKM_00768 3.27e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHAAAKM_00769 7.92e-221 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHAAAKM_00770 3.74e-182 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHAAAKM_00771 3.35e-55 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEHAAAKM_00772 2.46e-302 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEHAAAKM_00773 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEHAAAKM_00774 2.8e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEHAAAKM_00775 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NEHAAAKM_00776 4.69e-226 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEHAAAKM_00777 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEHAAAKM_00778 1.69e-06 - - - - - - - -
NEHAAAKM_00779 2.1e-31 - - - - - - - -
NEHAAAKM_00780 5.41e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_00781 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEHAAAKM_00782 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
NEHAAAKM_00783 5.56e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NEHAAAKM_00784 1.34e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEHAAAKM_00785 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NEHAAAKM_00786 2.08e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEHAAAKM_00787 1.63e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NEHAAAKM_00788 1.64e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEHAAAKM_00789 4.96e-270 - - - S - - - SLAP domain
NEHAAAKM_00790 1.15e-154 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
NEHAAAKM_00791 7.18e-187 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NEHAAAKM_00792 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEHAAAKM_00793 4.16e-51 ynzC - - S - - - UPF0291 protein
NEHAAAKM_00794 1.3e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
NEHAAAKM_00795 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHAAAKM_00796 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHAAAKM_00797 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NEHAAAKM_00798 8.61e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NEHAAAKM_00799 1.65e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NEHAAAKM_00800 2.03e-251 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NEHAAAKM_00801 2.21e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NEHAAAKM_00802 1.76e-235 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEHAAAKM_00803 5.86e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NEHAAAKM_00804 1.22e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEHAAAKM_00805 1.5e-176 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEHAAAKM_00806 3.93e-181 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NEHAAAKM_00807 6.38e-254 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NEHAAAKM_00808 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEHAAAKM_00809 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEHAAAKM_00810 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NEHAAAKM_00811 1.19e-259 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NEHAAAKM_00812 3.75e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NEHAAAKM_00813 1.61e-64 ylxQ - - J - - - ribosomal protein
NEHAAAKM_00814 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEHAAAKM_00815 2.77e-78 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEHAAAKM_00816 1.64e-198 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEHAAAKM_00817 5.35e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NEHAAAKM_00818 6.02e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEHAAAKM_00819 3.74e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEHAAAKM_00820 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NEHAAAKM_00821 6.87e-277 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEHAAAKM_00822 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEHAAAKM_00823 1.09e-226 - - - L - - - Belongs to the 'phage' integrase family
NEHAAAKM_00830 7e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEHAAAKM_00831 1.21e-16 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_00832 1.71e-102 - - - S - - - DNA binding
NEHAAAKM_00837 2.18e-07 - - - - - - - -
NEHAAAKM_00838 3.08e-125 - - - S - - - AntA/AntB antirepressor
NEHAAAKM_00843 3.9e-08 - - - K - - - DNA-binding protein
NEHAAAKM_00848 5.51e-71 - - - S - - - Protein of unknown function (DUF1071)
NEHAAAKM_00849 4.5e-41 - - - S - - - Conserved phage C-terminus (Phg_2220_C)
NEHAAAKM_00850 1.21e-61 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NEHAAAKM_00856 5.99e-52 - - - L - - - Endodeoxyribonuclease RusA
NEHAAAKM_00857 1.08e-10 - - - - - - - -
NEHAAAKM_00865 8.27e-46 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
NEHAAAKM_00866 7.69e-16 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
NEHAAAKM_00867 1.27e-47 - - - L ko:K07474 - ko00000 Terminase small subunit
NEHAAAKM_00868 9.32e-289 - - - S - - - Terminase-like family
NEHAAAKM_00869 6.56e-176 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
NEHAAAKM_00870 3.22e-124 - - - S - - - Phage Mu protein F like protein
NEHAAAKM_00871 1.14e-16 - - - S - - - Lysin motif
NEHAAAKM_00872 2.77e-137 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
NEHAAAKM_00873 2.06e-75 - - - - - - - -
NEHAAAKM_00874 1.83e-181 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2184)
NEHAAAKM_00876 2.18e-96 - - - - - - - -
NEHAAAKM_00877 1.8e-59 - - - - - - - -
NEHAAAKM_00878 7.95e-69 - - - - - - - -
NEHAAAKM_00879 7.86e-194 - - - S - - - Protein of unknown function (DUF3383)
NEHAAAKM_00880 1.33e-73 - - - - - - - -
NEHAAAKM_00883 0.0 - - - L - - - Phage tail tape measure protein TP901
NEHAAAKM_00884 1.06e-69 - - - M - - - LysM domain
NEHAAAKM_00885 6.91e-61 - - - - - - - -
NEHAAAKM_00886 1.11e-128 - - - - - - - -
NEHAAAKM_00887 4.6e-63 - - - - - - - -
NEHAAAKM_00888 1.37e-42 - - - - - - - -
NEHAAAKM_00889 2.78e-156 - - - S - - - Baseplate J-like protein
NEHAAAKM_00891 8.78e-42 - - - - - - - -
NEHAAAKM_00897 9.46e-58 - - - - - - - -
NEHAAAKM_00898 5.57e-26 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
NEHAAAKM_00901 1.73e-24 - - - - - - - -
NEHAAAKM_00902 3.07e-39 - - - - - - - -
NEHAAAKM_00903 3.06e-220 - - - M - - - Glycosyl hydrolases family 25
NEHAAAKM_00904 5.3e-32 - - - - - - - -
NEHAAAKM_00905 9.71e-47 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NEHAAAKM_00906 7e-131 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NEHAAAKM_00907 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NEHAAAKM_00908 1.15e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEHAAAKM_00909 4.39e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEHAAAKM_00911 5.01e-55 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NEHAAAKM_00912 4.97e-64 - - - S - - - Metal binding domain of Ada
NEHAAAKM_00913 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
NEHAAAKM_00914 3.03e-177 lysR5 - - K - - - LysR substrate binding domain
NEHAAAKM_00915 2.4e-297 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
NEHAAAKM_00916 6.6e-33 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEHAAAKM_00917 2.01e-135 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
NEHAAAKM_00918 1.76e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NEHAAAKM_00919 1.07e-287 - - - S - - - Sterol carrier protein domain
NEHAAAKM_00920 4.04e-29 - - - - - - - -
NEHAAAKM_00921 6.93e-140 - - - K - - - LysR substrate binding domain
NEHAAAKM_00922 1.13e-126 - - - - - - - -
NEHAAAKM_00923 5.04e-154 - - - G - - - Antibiotic biosynthesis monooxygenase
NEHAAAKM_00924 5.73e-153 - - - - - - - -
NEHAAAKM_00925 8.93e-108 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_00926 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NEHAAAKM_00927 1.15e-64 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NEHAAAKM_00928 5.51e-35 - - - - - - - -
NEHAAAKM_00929 8.71e-31 - - - G - - - Ribose/Galactose Isomerase
NEHAAAKM_00930 6.13e-70 - - - K - - - sequence-specific DNA binding
NEHAAAKM_00931 5.97e-55 - - - S - - - SnoaL-like domain
NEHAAAKM_00932 0.0 - - - L - - - PLD-like domain
NEHAAAKM_00933 2.19e-48 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEHAAAKM_00934 2.22e-296 - - - E ko:K03294 - ko00000 amino acid
NEHAAAKM_00935 3.61e-288 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_00936 6.83e-133 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
NEHAAAKM_00937 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NEHAAAKM_00938 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NEHAAAKM_00939 2.95e-283 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NEHAAAKM_00940 3.06e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEHAAAKM_00941 5.47e-151 - - - - - - - -
NEHAAAKM_00942 2.83e-205 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEHAAAKM_00944 1.22e-136 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEHAAAKM_00945 2e-149 - - - S - - - Peptidase family M23
NEHAAAKM_00946 5.18e-90 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEHAAAKM_00947 1.86e-114 ymdB - - S - - - Macro domain protein
NEHAAAKM_00949 9.12e-282 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_00950 1.34e-22 - - - S - - - CRISPR-associated protein (Cas_Csn2)
NEHAAAKM_00951 6.94e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NEHAAAKM_00952 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NEHAAAKM_00953 1.08e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NEHAAAKM_00954 1.74e-224 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NEHAAAKM_00955 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEHAAAKM_00956 1.37e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEHAAAKM_00957 4.11e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NEHAAAKM_00958 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NEHAAAKM_00959 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NEHAAAKM_00960 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEHAAAKM_00961 9e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEHAAAKM_00962 4.34e-166 - - - S - - - Peptidase family M23
NEHAAAKM_00963 5.37e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NEHAAAKM_00964 2.8e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NEHAAAKM_00965 8.12e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEHAAAKM_00966 2.86e-307 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NEHAAAKM_00967 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
NEHAAAKM_00968 1.33e-161 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEHAAAKM_00969 1.65e-180 - - - - - - - -
NEHAAAKM_00970 2.54e-176 - - - - - - - -
NEHAAAKM_00971 3.85e-193 - - - - - - - -
NEHAAAKM_00972 3.49e-36 - - - - - - - -
NEHAAAKM_00973 1.27e-133 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEHAAAKM_00974 4.01e-184 - - - - - - - -
NEHAAAKM_00975 4.4e-215 - - - - - - - -
NEHAAAKM_00976 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NEHAAAKM_00977 1.28e-150 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NEHAAAKM_00978 4.87e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NEHAAAKM_00979 6.67e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NEHAAAKM_00980 5.87e-228 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NEHAAAKM_00981 3.02e-173 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
NEHAAAKM_00982 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NEHAAAKM_00983 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NEHAAAKM_00984 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NEHAAAKM_00985 1.66e-116 ypmB - - S - - - Protein conserved in bacteria
NEHAAAKM_00986 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NEHAAAKM_00987 6.91e-149 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NEHAAAKM_00988 1.92e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEHAAAKM_00989 1.51e-171 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NEHAAAKM_00990 1.87e-300 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NEHAAAKM_00991 8.47e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NEHAAAKM_00992 1.18e-139 ypsA - - S - - - Belongs to the UPF0398 family
NEHAAAKM_00993 1.85e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NEHAAAKM_00994 1.68e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NEHAAAKM_00995 6.74e-309 cpdA - - S - - - Calcineurin-like phosphoesterase
NEHAAAKM_00996 9.67e-104 - - - - - - - -
NEHAAAKM_00997 9.91e-150 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
NEHAAAKM_00998 3.56e-47 - - - - - - - -
NEHAAAKM_00999 4.13e-83 - - - - - - - -
NEHAAAKM_01002 1.51e-159 - - - - - - - -
NEHAAAKM_01003 4.83e-136 pncA - - Q - - - Isochorismatase family
NEHAAAKM_01004 1.24e-08 - - - - - - - -
NEHAAAKM_01005 1.73e-48 - - - - - - - -
NEHAAAKM_01006 0.0 snf - - KL - - - domain protein
NEHAAAKM_01007 9.39e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEHAAAKM_01008 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEHAAAKM_01009 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEHAAAKM_01010 9.08e-234 - - - K - - - Transcriptional regulator
NEHAAAKM_01011 1.94e-217 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NEHAAAKM_01012 5.91e-08 - - - - - - - -
NEHAAAKM_01013 7.23e-78 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
NEHAAAKM_01014 8.17e-18 - - - S - - - Transposase C of IS166 homeodomain
NEHAAAKM_01015 4.09e-11 - - - L ko:K07496 - ko00000 Transposase
NEHAAAKM_01016 2.3e-36 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEHAAAKM_01017 2.66e-157 - - - S - - - Protein of unknown function (DUF1275)
NEHAAAKM_01018 3.35e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEHAAAKM_01019 4.36e-142 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
NEHAAAKM_01020 1.5e-90 - - - - - - - -
NEHAAAKM_01021 1.24e-258 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
NEHAAAKM_01022 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEHAAAKM_01023 4.7e-204 - - - S - - - EDD domain protein, DegV family
NEHAAAKM_01024 2.06e-88 - - - - - - - -
NEHAAAKM_01025 0.0 FbpA - - K - - - Fibronectin-binding protein
NEHAAAKM_01026 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEHAAAKM_01027 4.13e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NEHAAAKM_01028 3.24e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEHAAAKM_01029 3.16e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEHAAAKM_01030 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NEHAAAKM_01031 1.61e-70 - - - - - - - -
NEHAAAKM_01033 8.81e-40 - - - M - - - Mycoplasma protein of unknown function, DUF285
NEHAAAKM_01034 9.86e-146 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NEHAAAKM_01036 7.46e-76 - - - S - - - SIR2-like domain
NEHAAAKM_01037 2.64e-49 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
NEHAAAKM_01038 2.57e-61 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NEHAAAKM_01039 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NEHAAAKM_01040 5.22e-54 - - - S - - - RloB-like protein
NEHAAAKM_01041 1.35e-208 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
NEHAAAKM_01042 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
NEHAAAKM_01043 0.0 - - - S - - - SLAP domain
NEHAAAKM_01045 5.93e-302 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
NEHAAAKM_01046 1.43e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
NEHAAAKM_01047 1.65e-303 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEHAAAKM_01049 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEHAAAKM_01050 4.21e-129 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NEHAAAKM_01051 2.02e-137 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHAAAKM_01052 9.63e-204 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHAAAKM_01053 2.76e-86 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEHAAAKM_01054 4.53e-238 - - - L ko:K07478 - ko00000 AAA C-terminal domain
NEHAAAKM_01055 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NEHAAAKM_01056 5.74e-108 - - - K - - - Acetyltransferase (GNAT) domain
NEHAAAKM_01057 1.87e-290 - - - S - - - Putative peptidoglycan binding domain
NEHAAAKM_01058 7.89e-124 - - - S - - - ECF-type riboflavin transporter, S component
NEHAAAKM_01059 3.1e-127 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NEHAAAKM_01060 1.59e-259 pbpX1 - - V - - - Beta-lactamase
NEHAAAKM_01061 1.12e-149 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NEHAAAKM_01062 1.12e-104 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHAAAKM_01063 4.87e-262 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NEHAAAKM_01064 5.94e-148 - - - I - - - Acid phosphatase homologues
NEHAAAKM_01065 2.25e-241 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NEHAAAKM_01066 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
NEHAAAKM_01067 3.6e-106 - - - C - - - Flavodoxin
NEHAAAKM_01068 4.23e-46 - - - L - - - An automated process has identified a potential problem with this gene model
NEHAAAKM_01069 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEHAAAKM_01070 4.97e-311 ynbB - - P - - - aluminum resistance
NEHAAAKM_01071 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
NEHAAAKM_01072 0.0 - - - E - - - Amino acid permease
NEHAAAKM_01073 7.88e-121 - - - C - - - Pyridoxamine 5'-phosphate oxidase
NEHAAAKM_01074 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NEHAAAKM_01075 8.65e-145 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NEHAAAKM_01076 1.31e-16 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NEHAAAKM_01077 2.95e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEHAAAKM_01078 7.64e-88 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEHAAAKM_01079 2.15e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
NEHAAAKM_01080 7.7e-126 - - - L - - - Helix-turn-helix domain
NEHAAAKM_01081 4.47e-148 - - - L ko:K07497 - ko00000 hmm pf00665
NEHAAAKM_01082 1.43e-33 - - - L ko:K07497 - ko00000 hmm pf00665
NEHAAAKM_01083 1.8e-36 - - - M - - - LysM domain protein
NEHAAAKM_01084 9.44e-63 - - - M - - - LysM domain protein
NEHAAAKM_01085 9.11e-110 - - - C - - - Aldo keto reductase
NEHAAAKM_01086 9.4e-232 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NEHAAAKM_01087 1.4e-313 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NEHAAAKM_01088 4.67e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NEHAAAKM_01089 2.09e-180 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
NEHAAAKM_01090 8.35e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NEHAAAKM_01091 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEHAAAKM_01092 1.5e-195 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NEHAAAKM_01093 1e-168 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEHAAAKM_01094 2.15e-198 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NEHAAAKM_01095 2.4e-118 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
NEHAAAKM_01096 7.2e-49 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
NEHAAAKM_01097 3.67e-88 - - - P - - - NhaP-type Na H and K H
NEHAAAKM_01098 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
NEHAAAKM_01099 8.63e-191 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
NEHAAAKM_01100 1.8e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NEHAAAKM_01101 5.13e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NEHAAAKM_01102 3.86e-204 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEHAAAKM_01103 9.58e-112 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
NEHAAAKM_01104 6.08e-161 yagE - - E - - - Amino acid permease
NEHAAAKM_01105 8.49e-85 - - - E - - - amino acid
NEHAAAKM_01106 3.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_01107 2.16e-193 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
NEHAAAKM_01108 6.64e-185 - - - F - - - Phosphorylase superfamily
NEHAAAKM_01109 1.05e-176 - - - F - - - Phosphorylase superfamily
NEHAAAKM_01110 9.82e-80 - - - F - - - NUDIX domain
NEHAAAKM_01111 1.83e-103 - - - S - - - AAA domain
NEHAAAKM_01112 1.5e-150 - - - S - - - F420-0:Gamma-glutamyl ligase
NEHAAAKM_01113 1.87e-170 - - - S - - - Alpha/beta hydrolase family
NEHAAAKM_01114 2.95e-123 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEHAAAKM_01115 2e-299 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEHAAAKM_01116 1.43e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NEHAAAKM_01117 8.21e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEHAAAKM_01118 5.45e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NEHAAAKM_01119 1.4e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NEHAAAKM_01120 1.96e-148 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NEHAAAKM_01121 1.13e-41 - - - M - - - Lysin motif
NEHAAAKM_01122 1.64e-143 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEHAAAKM_01123 4.65e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEHAAAKM_01124 7.57e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEHAAAKM_01125 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEHAAAKM_01126 1.13e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHAAAKM_01127 6.74e-213 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NEHAAAKM_01128 1.21e-213 yitL - - S ko:K00243 - ko00000 S1 domain
NEHAAAKM_01129 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NEHAAAKM_01130 5.46e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEHAAAKM_01131 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NEHAAAKM_01132 1.25e-38 - - - S - - - Protein of unknown function (DUF2929)
NEHAAAKM_01133 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NEHAAAKM_01134 1.37e-14 - - - - - - - -
NEHAAAKM_01136 3.9e-147 - - - M - - - hydrolase, family 25
NEHAAAKM_01137 6.31e-50 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NEHAAAKM_01147 9.62e-205 - - - S - - - Phage minor structural protein
NEHAAAKM_01149 7.87e-194 - - - D - - - domain protein
NEHAAAKM_01157 2.13e-181 - - - S - - - peptidase activity
NEHAAAKM_01158 7.16e-84 - - - S - - - Clp protease
NEHAAAKM_01159 5.55e-170 - - - S - - - Phage portal protein
NEHAAAKM_01161 3.61e-189 - - - S - - - Phage Terminase
NEHAAAKM_01164 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
NEHAAAKM_01167 2.27e-187 - - - L - - - Helicase C-terminal domain protein
NEHAAAKM_01169 3.86e-87 - - - S - - - AAA domain
NEHAAAKM_01170 8.93e-33 - - - S - - - HNH endonuclease
NEHAAAKM_01177 3.44e-23 - - - - - - - -
NEHAAAKM_01180 1.18e-45 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
NEHAAAKM_01182 1.24e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEHAAAKM_01184 2.99e-31 - - - S - - - Hypothetical protein (DUF2513)
NEHAAAKM_01187 3.54e-170 - - - L - - - Belongs to the 'phage' integrase family
NEHAAAKM_01188 5.14e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NEHAAAKM_01189 3.57e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
NEHAAAKM_01190 1.18e-183 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHAAAKM_01191 6.82e-223 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEHAAAKM_01192 0.0 oatA - - I - - - Acyltransferase
NEHAAAKM_01193 1.88e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEHAAAKM_01194 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEHAAAKM_01195 1.58e-140 yngC - - S - - - SNARE associated Golgi protein
NEHAAAKM_01196 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
NEHAAAKM_01197 1.14e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHAAAKM_01198 1.83e-190 yxeH - - S - - - hydrolase
NEHAAAKM_01199 6.32e-41 - - - S - - - reductase
NEHAAAKM_01200 2.98e-50 - - - S - - - reductase
NEHAAAKM_01201 1.19e-43 - - - S - - - reductase
NEHAAAKM_01202 4.66e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEHAAAKM_01203 5.51e-284 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEHAAAKM_01204 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NEHAAAKM_01205 7.1e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NEHAAAKM_01206 1.8e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEHAAAKM_01207 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEHAAAKM_01208 3.8e-80 - - - - - - - -
NEHAAAKM_01209 4.8e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NEHAAAKM_01210 1.3e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEHAAAKM_01211 5.26e-15 - - - - - - - -
NEHAAAKM_01213 9.28e-317 - - - S - - - Putative threonine/serine exporter
NEHAAAKM_01214 1.05e-226 citR - - K - - - Putative sugar-binding domain
NEHAAAKM_01215 2.41e-66 - - - - - - - -
NEHAAAKM_01216 7.91e-14 - - - - - - - -
NEHAAAKM_01217 8.1e-87 - - - S - - - Domain of unknown function DUF1828
NEHAAAKM_01218 5.38e-125 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NEHAAAKM_01219 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01220 2.58e-189 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NEHAAAKM_01221 9.9e-30 - - - - - - - -
NEHAAAKM_01222 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
NEHAAAKM_01223 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NEHAAAKM_01224 1.79e-214 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NEHAAAKM_01225 1.6e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NEHAAAKM_01226 5.17e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NEHAAAKM_01227 8.46e-197 - - - I - - - Alpha/beta hydrolase family
NEHAAAKM_01228 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NEHAAAKM_01229 5.26e-171 - - - H - - - Aldolase/RraA
NEHAAAKM_01230 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEHAAAKM_01231 1.66e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NEHAAAKM_01232 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHAAAKM_01233 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NEHAAAKM_01234 3.32e-122 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01235 3.87e-241 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEHAAAKM_01236 2.16e-205 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEHAAAKM_01237 2.57e-223 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NEHAAAKM_01238 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NEHAAAKM_01239 7.89e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEHAAAKM_01240 1e-228 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEHAAAKM_01241 1.8e-316 yifK - - E ko:K03293 - ko00000 Amino acid permease
NEHAAAKM_01242 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NEHAAAKM_01243 1.58e-10 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
NEHAAAKM_01244 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
NEHAAAKM_01245 2.46e-48 - - - - - - - -
NEHAAAKM_01247 1.46e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NEHAAAKM_01248 4.6e-113 - - - K - - - GNAT family
NEHAAAKM_01249 5.25e-258 XK27_00915 - - C - - - Luciferase-like monooxygenase
NEHAAAKM_01250 4.45e-156 rbtT - - P ko:K13021 - ko00000,ko02000 Major Facilitator Superfamily
NEHAAAKM_01251 2.81e-76 - - - EGP - - - Major Facilitator
NEHAAAKM_01252 1.27e-42 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NEHAAAKM_01254 2.99e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEHAAAKM_01255 0.0 - - - L - - - Plasmid pRiA4b ORF-3-like protein
NEHAAAKM_01256 8.09e-314 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEHAAAKM_01257 6.21e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NEHAAAKM_01258 1.53e-142 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
NEHAAAKM_01259 5.75e-152 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NEHAAAKM_01260 6.44e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NEHAAAKM_01261 2.25e-137 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NEHAAAKM_01262 8.41e-42 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NEHAAAKM_01263 2.24e-71 ykoJ - - S - - - Peptidase propeptide and YPEB domain
NEHAAAKM_01264 1.23e-175 - - - L - - - An automated process has identified a potential problem with this gene model
NEHAAAKM_01266 3.68e-176 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NEHAAAKM_01267 3.05e-110 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NEHAAAKM_01268 1.31e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NEHAAAKM_01269 1.15e-104 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NEHAAAKM_01270 1.32e-114 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NEHAAAKM_01271 1.16e-13 - - - L - - - Psort location Cytoplasmic, score
NEHAAAKM_01272 7.42e-171 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NEHAAAKM_01273 4.36e-93 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEHAAAKM_01274 2.43e-95 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NEHAAAKM_01275 2.33e-130 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
NEHAAAKM_01276 3.87e-15 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
NEHAAAKM_01277 1.63e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NEHAAAKM_01278 1.73e-227 - - - S - - - Conserved hypothetical protein 698
NEHAAAKM_01280 1.21e-243 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEHAAAKM_01281 1.94e-130 - - - I - - - PAP2 superfamily
NEHAAAKM_01282 1.23e-187 - - - S - - - Uncharacterised protein, DegV family COG1307
NEHAAAKM_01283 1.43e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEHAAAKM_01284 3.73e-72 - - - S - - - Domain of unknown function (DUF4767)
NEHAAAKM_01285 3.87e-16 - - - S - - - Domain of unknown function (DUF4767)
NEHAAAKM_01286 2.08e-95 yfhC - - C - - - nitroreductase
NEHAAAKM_01287 8.72e-258 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHAAAKM_01288 1.31e-56 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHAAAKM_01289 4.06e-39 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHAAAKM_01290 4.22e-288 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHAAAKM_01291 0.0 - - - I - - - Protein of unknown function (DUF2974)
NEHAAAKM_01292 4.2e-249 pbpX1 - - V - - - Beta-lactamase
NEHAAAKM_01293 2.48e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEHAAAKM_01294 9.03e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEHAAAKM_01295 6.89e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEHAAAKM_01296 3.66e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEHAAAKM_01297 3.29e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NEHAAAKM_01298 8.62e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NEHAAAKM_01299 1.39e-312 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEHAAAKM_01300 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NEHAAAKM_01301 6.25e-246 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEHAAAKM_01302 1.27e-220 potE - - E - - - Amino Acid
NEHAAAKM_01303 2.58e-48 potE - - E - - - Amino Acid
NEHAAAKM_01304 1.59e-136 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NEHAAAKM_01305 3.04e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEHAAAKM_01306 2.56e-291 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEHAAAKM_01307 5.76e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEHAAAKM_01308 5.43e-191 - - - - - - - -
NEHAAAKM_01309 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEHAAAKM_01310 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEHAAAKM_01311 3.64e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NEHAAAKM_01312 2.57e-226 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NEHAAAKM_01313 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NEHAAAKM_01314 2.7e-126 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NEHAAAKM_01315 1.42e-244 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NEHAAAKM_01316 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEHAAAKM_01317 5.21e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NEHAAAKM_01318 9.94e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NEHAAAKM_01319 3.91e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NEHAAAKM_01320 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NEHAAAKM_01321 2.79e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEHAAAKM_01322 1.75e-211 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NEHAAAKM_01323 0.0 - - - L - - - Nuclease-related domain
NEHAAAKM_01324 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEHAAAKM_01325 2.31e-148 - - - S - - - repeat protein
NEHAAAKM_01326 4.7e-163 pgm - - G - - - Phosphoglycerate mutase family
NEHAAAKM_01327 4.47e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEHAAAKM_01328 9.98e-75 XK27_04120 - - S - - - Putative amino acid metabolism
NEHAAAKM_01329 1.62e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NEHAAAKM_01330 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEHAAAKM_01331 1.22e-55 - - - - - - - -
NEHAAAKM_01332 5.18e-134 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NEHAAAKM_01333 2.32e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NEHAAAKM_01334 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEHAAAKM_01335 6.3e-138 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NEHAAAKM_01336 4.01e-192 ylmH - - S - - - S4 domain protein
NEHAAAKM_01337 2.42e-60 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
NEHAAAKM_01338 1.43e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEHAAAKM_01339 2.52e-300 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEHAAAKM_01340 3.3e-315 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEHAAAKM_01341 3.14e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NEHAAAKM_01342 3.88e-264 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEHAAAKM_01343 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEHAAAKM_01344 4.43e-224 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEHAAAKM_01345 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NEHAAAKM_01346 6.55e-72 ftsL - - D - - - Cell division protein FtsL
NEHAAAKM_01347 1.49e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEHAAAKM_01348 5.63e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NEHAAAKM_01349 1.02e-72 - - - S - - - Protein of unknown function (DUF3397)
NEHAAAKM_01350 1.4e-09 - - - S - - - Protein of unknown function (DUF4044)
NEHAAAKM_01351 5.43e-122 mreD - - - ko:K03571 - ko00000,ko03036 -
NEHAAAKM_01352 8.27e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NEHAAAKM_01353 8.26e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NEHAAAKM_01354 6.18e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
NEHAAAKM_01355 1.06e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
NEHAAAKM_01356 1.22e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NEHAAAKM_01357 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEHAAAKM_01358 2.91e-67 - - - - - - - -
NEHAAAKM_01359 3.02e-166 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
NEHAAAKM_01360 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEHAAAKM_01361 9.25e-13 - - - S - - - PD-(D/E)XK nuclease family transposase
NEHAAAKM_01362 8.53e-59 - - - - - - - -
NEHAAAKM_01363 3.33e-123 - - - S - - - Protein of unknown function (DUF3990)
NEHAAAKM_01364 4.08e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NEHAAAKM_01365 1.06e-86 - - - S - - - GtrA-like protein
NEHAAAKM_01366 3.97e-57 - - - S - - - PD-(D/E)XK nuclease family transposase
NEHAAAKM_01367 6.01e-153 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEHAAAKM_01368 2.1e-232 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NEHAAAKM_01369 3.48e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NEHAAAKM_01370 4.1e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NEHAAAKM_01371 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NEHAAAKM_01372 3.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEHAAAKM_01373 8.08e-110 - - - S - - - Protein of unknown function (DUF1694)
NEHAAAKM_01374 5.98e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NEHAAAKM_01375 1.35e-56 - - - - - - - -
NEHAAAKM_01376 9.45e-104 uspA - - T - - - universal stress protein
NEHAAAKM_01377 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NEHAAAKM_01378 5.13e-46 - - - S - - - Protein of unknown function (DUF2969)
NEHAAAKM_01379 1.59e-68 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NEHAAAKM_01380 4.81e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NEHAAAKM_01381 2.54e-42 - - - S - - - Protein of unknown function (DUF1146)
NEHAAAKM_01382 2.45e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NEHAAAKM_01383 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEHAAAKM_01384 1.04e-221 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEHAAAKM_01385 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEHAAAKM_01386 3.24e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEHAAAKM_01387 2.57e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEHAAAKM_01388 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEHAAAKM_01389 1.01e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NEHAAAKM_01390 5.28e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEHAAAKM_01391 1.36e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEHAAAKM_01392 1.24e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEHAAAKM_01393 6.6e-237 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEHAAAKM_01394 9.98e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NEHAAAKM_01395 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NEHAAAKM_01398 3.94e-250 ampC - - V - - - Beta-lactamase
NEHAAAKM_01399 4.63e-274 - - - EGP - - - Major Facilitator
NEHAAAKM_01400 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NEHAAAKM_01401 1.52e-136 vanZ - - V - - - VanZ like family
NEHAAAKM_01402 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEHAAAKM_01403 0.0 yclK - - T - - - Histidine kinase
NEHAAAKM_01404 4.96e-167 - - - K - - - Transcriptional regulatory protein, C terminal
NEHAAAKM_01405 9.01e-90 - - - S - - - SdpI/YhfL protein family
NEHAAAKM_01406 1.93e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NEHAAAKM_01407 1.72e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NEHAAAKM_01408 3e-128 - - - M - - - Protein of unknown function (DUF3737)
NEHAAAKM_01410 1.07e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHAAAKM_01411 2.42e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NEHAAAKM_01412 3.69e-30 - - - - - - - -
NEHAAAKM_01413 1.94e-100 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NEHAAAKM_01414 1.68e-55 - - - - - - - -
NEHAAAKM_01415 8.19e-91 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
NEHAAAKM_01416 7.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
NEHAAAKM_01417 1.72e-222 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NEHAAAKM_01418 5.04e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NEHAAAKM_01419 5.65e-171 yebC - - K - - - Transcriptional regulatory protein
NEHAAAKM_01420 2.33e-120 - - - S - - - VanZ like family
NEHAAAKM_01421 1.49e-130 ylbE - - GM - - - NAD(P)H-binding
NEHAAAKM_01422 3.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEHAAAKM_01424 4.31e-204 - - - L ko:K07497 - ko00000 hmm pf00665
NEHAAAKM_01425 2.15e-127 - - - L - - - Helix-turn-helix domain
NEHAAAKM_01426 0.0 - - - E - - - Amino acid permease
NEHAAAKM_01428 1.14e-99 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEHAAAKM_01429 1.96e-110 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
NEHAAAKM_01430 2.64e-46 - - - - - - - -
NEHAAAKM_01431 1.67e-136 icaA - - M - - - Glycosyl transferase family group 2
NEHAAAKM_01432 2.21e-34 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
NEHAAAKM_01433 4.11e-44 - - - T - - - Putative diguanylate phosphodiesterase
NEHAAAKM_01434 1.74e-60 - - - T - - - Putative diguanylate phosphodiesterase
NEHAAAKM_01435 5.12e-199 ybcH - - D ko:K06889 - ko00000 Alpha beta
NEHAAAKM_01436 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHAAAKM_01437 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHAAAKM_01438 8.39e-195 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEHAAAKM_01439 2.52e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NEHAAAKM_01440 3.07e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEHAAAKM_01441 2.85e-153 - - - - - - - -
NEHAAAKM_01442 3.23e-98 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
NEHAAAKM_01443 8.04e-190 - - - S - - - hydrolase
NEHAAAKM_01444 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEHAAAKM_01445 2.76e-221 ybbR - - S - - - YbbR-like protein
NEHAAAKM_01446 2.13e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEHAAAKM_01447 3.46e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHAAAKM_01448 3.69e-170 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01449 8.77e-173 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01450 1.25e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NEHAAAKM_01451 2.84e-208 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NEHAAAKM_01452 1.51e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEHAAAKM_01453 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NEHAAAKM_01454 1.1e-232 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NEHAAAKM_01455 1.64e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEHAAAKM_01456 2.3e-197 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEHAAAKM_01457 3.07e-124 - - - - - - - -
NEHAAAKM_01458 1.18e-253 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NEHAAAKM_01459 5.46e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEHAAAKM_01460 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NEHAAAKM_01461 2.86e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEHAAAKM_01462 9.53e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NEHAAAKM_01464 0.0 - - - - - - - -
NEHAAAKM_01465 0.0 ycaM - - E - - - amino acid
NEHAAAKM_01466 1.43e-178 - - - S - - - Cysteine-rich secretory protein family
NEHAAAKM_01467 7.65e-101 - - - K - - - MerR HTH family regulatory protein
NEHAAAKM_01468 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NEHAAAKM_01469 4.64e-63 - - - S - - - Domain of unknown function (DUF4811)
NEHAAAKM_01470 4.76e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NEHAAAKM_01471 3.16e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01472 0.0 - - - S - - - SH3-like domain
NEHAAAKM_01473 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEHAAAKM_01474 8.59e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NEHAAAKM_01475 2.78e-251 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NEHAAAKM_01476 2.44e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NEHAAAKM_01477 1.55e-117 - - - S - - - Short repeat of unknown function (DUF308)
NEHAAAKM_01478 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEHAAAKM_01479 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEHAAAKM_01480 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NEHAAAKM_01481 3.42e-232 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEHAAAKM_01482 3.31e-239 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NEHAAAKM_01483 4.04e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEHAAAKM_01484 3.54e-230 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NEHAAAKM_01485 8.33e-27 - - - - - - - -
NEHAAAKM_01486 2.24e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEHAAAKM_01487 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEHAAAKM_01488 1.55e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEHAAAKM_01489 9.44e-169 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NEHAAAKM_01490 2.68e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NEHAAAKM_01491 5.04e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NEHAAAKM_01492 1.94e-268 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NEHAAAKM_01493 3.03e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NEHAAAKM_01494 1.17e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEHAAAKM_01495 3.92e-123 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEHAAAKM_01496 1.63e-154 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NEHAAAKM_01497 1.39e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NEHAAAKM_01498 5.49e-301 ymfH - - S - - - Peptidase M16
NEHAAAKM_01499 1.47e-284 ymfF - - S - - - Peptidase M16 inactive domain protein
NEHAAAKM_01500 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NEHAAAKM_01501 3.12e-91 - - - S - - - Protein of unknown function (DUF1149)
NEHAAAKM_01502 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEHAAAKM_01503 2.19e-270 XK27_05220 - - S - - - AI-2E family transporter
NEHAAAKM_01504 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NEHAAAKM_01505 1.01e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NEHAAAKM_01506 3.77e-122 - - - S - - - SNARE associated Golgi protein
NEHAAAKM_01507 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NEHAAAKM_01508 7.96e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEHAAAKM_01509 1.91e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEHAAAKM_01510 1.7e-147 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NEHAAAKM_01511 2.44e-143 - - - S - - - CYTH
NEHAAAKM_01512 5.74e-148 yjbH - - Q - - - Thioredoxin
NEHAAAKM_01513 2.63e-205 coiA - - S ko:K06198 - ko00000 Competence protein
NEHAAAKM_01514 1.5e-178 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NEHAAAKM_01515 6.28e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEHAAAKM_01516 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEHAAAKM_01517 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NEHAAAKM_01518 2.6e-37 - - - - - - - -
NEHAAAKM_01519 7.23e-50 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NEHAAAKM_01520 3.61e-212 - - - V - - - ABC transporter transmembrane region
NEHAAAKM_01521 1.26e-176 - - - - - - - -
NEHAAAKM_01525 9.3e-25 - - - - - - - -
NEHAAAKM_01526 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NEHAAAKM_01527 5.93e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NEHAAAKM_01528 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NEHAAAKM_01529 1.76e-181 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
NEHAAAKM_01530 7.76e-98 - - - - - - - -
NEHAAAKM_01531 1.74e-111 - - - - - - - -
NEHAAAKM_01532 2.79e-185 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NEHAAAKM_01533 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEHAAAKM_01534 1.94e-150 ybcH - - D ko:K06889 - ko00000 Alpha beta
NEHAAAKM_01535 1.04e-48 ybcH - - D ko:K06889 - ko00000 Alpha beta
NEHAAAKM_01536 7.74e-61 - - - - - - - -
NEHAAAKM_01537 4.42e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NEHAAAKM_01538 1.22e-272 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NEHAAAKM_01539 3.22e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NEHAAAKM_01540 3.44e-209 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NEHAAAKM_01541 9.98e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NEHAAAKM_01542 5.14e-105 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NEHAAAKM_01543 7.46e-113 gtcA1 - - S - - - Teichoic acid glycosylation protein
NEHAAAKM_01544 1.62e-278 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEHAAAKM_01546 3.76e-316 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHAAAKM_01547 5.96e-283 yfmL - - L - - - DEAD DEAH box helicase
NEHAAAKM_01548 2.16e-79 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEHAAAKM_01549 6.73e-78 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEHAAAKM_01550 7.32e-157 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHAAAKM_01551 6.74e-269 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHAAAKM_01552 5.83e-67 - - - L - - - PFAM transposase, IS4 family protein
NEHAAAKM_01553 2.88e-113 - - - L - - - PFAM transposase, IS4 family protein
NEHAAAKM_01554 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHAAAKM_01555 8.59e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NEHAAAKM_01556 0.0 yhdP - - S - - - Transporter associated domain
NEHAAAKM_01557 2.14e-154 - - - C - - - nitroreductase
NEHAAAKM_01558 1.76e-52 - - - - - - - -
NEHAAAKM_01559 1.96e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEHAAAKM_01560 1.52e-103 - - - - - - - -
NEHAAAKM_01561 6.89e-190 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NEHAAAKM_01562 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEHAAAKM_01563 7.44e-189 - - - S - - - hydrolase
NEHAAAKM_01564 1.85e-205 - - - S - - - Phospholipase, patatin family
NEHAAAKM_01565 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NEHAAAKM_01566 4.44e-174 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NEHAAAKM_01567 2.9e-79 - - - S - - - Enterocin A Immunity
NEHAAAKM_01568 3.18e-198 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NEHAAAKM_01569 6.63e-174 gntR - - K - - - UbiC transcription regulator-associated domain protein
NEHAAAKM_01570 1.01e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NEHAAAKM_01571 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEHAAAKM_01572 1.82e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEHAAAKM_01573 8.52e-215 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEHAAAKM_01574 7.29e-209 - - - C - - - Domain of unknown function (DUF4931)
NEHAAAKM_01575 2.2e-308 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEHAAAKM_01576 3.52e-296 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NEHAAAKM_01577 2.09e-110 - - - - - - - -
NEHAAAKM_01578 1.04e-211 - - - S - - - Protein of unknown function (DUF2974)
NEHAAAKM_01579 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01580 4.29e-122 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01581 3.39e-187 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEHAAAKM_01582 2.8e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01583 2.72e-60 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
NEHAAAKM_01584 5.43e-50 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
NEHAAAKM_01585 8.41e-314 - - - G - - - MFS/sugar transport protein
NEHAAAKM_01586 1.72e-129 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NEHAAAKM_01587 3.73e-254 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
NEHAAAKM_01588 1.29e-131 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
NEHAAAKM_01589 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01590 2.53e-106 - - - K - - - Transcriptional regulator, MarR family
NEHAAAKM_01591 2.05e-188 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHAAAKM_01592 1.07e-165 - - - F - - - glutamine amidotransferase
NEHAAAKM_01593 3.41e-312 steT - - E ko:K03294 - ko00000 amino acid
NEHAAAKM_01594 3.97e-33 steT - - E ko:K03294 - ko00000 amino acid
NEHAAAKM_01595 1.11e-256 steT - - E ko:K03294 - ko00000 amino acid
NEHAAAKM_01596 1.53e-176 - - - - - - - -
NEHAAAKM_01597 6.07e-223 ydhF - - S - - - Aldo keto reductase
NEHAAAKM_01598 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NEHAAAKM_01599 2.33e-230 pepA - - E - - - M42 glutamyl aminopeptidase
NEHAAAKM_01600 1.06e-195 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
NEHAAAKM_01601 0.0 qacA - - EGP - - - Major Facilitator
NEHAAAKM_01602 1.02e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEHAAAKM_01603 1.36e-302 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NEHAAAKM_01604 3.55e-28 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
NEHAAAKM_01605 8.97e-47 - - - - - - - -
NEHAAAKM_01606 5.94e-200 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEHAAAKM_01607 6.13e-110 - - - K - - - Acetyltransferase (GNAT) domain
NEHAAAKM_01608 6.61e-186 - - - S ko:K07133 - ko00000 cog cog1373
NEHAAAKM_01609 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NEHAAAKM_01610 1.52e-119 - - - K - - - Bacterial regulatory proteins, tetR family
NEHAAAKM_01611 0.0 qacA - - EGP - - - Major Facilitator
NEHAAAKM_01616 1.42e-122 - - - K - - - Acetyltransferase (GNAT) domain
NEHAAAKM_01617 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEHAAAKM_01618 1.01e-256 flp - - V - - - Beta-lactamase
NEHAAAKM_01619 2.79e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NEHAAAKM_01620 9.92e-187 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NEHAAAKM_01621 1.46e-75 - - - - - - - -
NEHAAAKM_01622 2.61e-148 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NEHAAAKM_01623 5.58e-219 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NEHAAAKM_01624 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEHAAAKM_01625 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEHAAAKM_01626 5.42e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEHAAAKM_01627 6.25e-268 camS - - S - - - sex pheromone
NEHAAAKM_01628 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEHAAAKM_01629 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NEHAAAKM_01630 2.26e-118 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NEHAAAKM_01632 2.62e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NEHAAAKM_01633 5.48e-173 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NEHAAAKM_01634 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEHAAAKM_01635 9.16e-287 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHAAAKM_01636 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEHAAAKM_01637 9.83e-261 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEHAAAKM_01638 1.91e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NEHAAAKM_01639 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEHAAAKM_01640 1.03e-261 - - - M - - - Glycosyl transferases group 1
NEHAAAKM_01641 3.02e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NEHAAAKM_01642 3.68e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
NEHAAAKM_01643 1.87e-159 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
NEHAAAKM_01644 2.17e-232 - - - - - - - -
NEHAAAKM_01645 1.15e-54 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHAAAKM_01646 7.83e-303 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHAAAKM_01649 4.41e-305 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NEHAAAKM_01650 1.18e-13 - - - - - - - -
NEHAAAKM_01651 6.39e-32 - - - S - - - transposase or invertase
NEHAAAKM_01652 3.98e-210 slpX - - S - - - SLAP domain
NEHAAAKM_01653 1.76e-65 slpX - - S - - - SLAP domain
NEHAAAKM_01654 1.43e-186 - - - K - - - SIS domain
NEHAAAKM_01655 3.01e-154 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NEHAAAKM_01656 1.03e-237 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NEHAAAKM_01657 1.12e-265 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEHAAAKM_01659 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
NEHAAAKM_01661 2.67e-148 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NEHAAAKM_01662 1.9e-153 - - - G - - - Antibiotic biosynthesis monooxygenase
NEHAAAKM_01663 9.01e-115 - - - G - - - Histidine phosphatase superfamily (branch 1)
NEHAAAKM_01664 8.92e-136 - - - G - - - Phosphoglycerate mutase family
NEHAAAKM_01665 5.68e-211 - - - D - - - nuclear chromosome segregation
NEHAAAKM_01666 1.33e-130 - - - M - - - LysM domain protein
NEHAAAKM_01667 2.57e-108 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHAAAKM_01668 6.31e-99 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHAAAKM_01669 1.83e-22 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHAAAKM_01670 1.25e-17 - - - - - - - -
NEHAAAKM_01671 1.32e-218 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
NEHAAAKM_01672 1.04e-41 - - - - - - - -
NEHAAAKM_01674 3.65e-90 - - - S - - - Iron-sulphur cluster biosynthesis
NEHAAAKM_01675 1.08e-145 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEHAAAKM_01676 3.31e-79 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NEHAAAKM_01678 1.79e-74 - - - L - - - Resolvase, N-terminal
NEHAAAKM_01679 4.18e-208 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEHAAAKM_01680 1.86e-243 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEHAAAKM_01684 4.26e-22 - - - L ko:K07467 - ko00000 Replication initiation factor
NEHAAAKM_01685 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHAAAKM_01686 5.23e-97 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NEHAAAKM_01687 1.48e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHAAAKM_01688 1.07e-141 tnpR1 - - L - - - Resolvase, N terminal domain
NEHAAAKM_01689 6.91e-92 - - - L - - - IS1381, transposase OrfA
NEHAAAKM_01690 4.87e-96 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEHAAAKM_01691 1.17e-38 - - - - - - - -
NEHAAAKM_01692 4.65e-184 - - - D - - - AAA domain
NEHAAAKM_01693 5.88e-212 repA - - S - - - Replication initiator protein A
NEHAAAKM_01694 1.14e-164 - - - S - - - Fic/DOC family
NEHAAAKM_01695 1.55e-154 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NEHAAAKM_01696 1.49e-290 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NEHAAAKM_01697 7.82e-80 - - - - - - - -
NEHAAAKM_01698 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
NEHAAAKM_01699 2.14e-312 - - - P - - - P-loop Domain of unknown function (DUF2791)
NEHAAAKM_01700 5.53e-173 - - - S - - - TerB-C domain
NEHAAAKM_01701 1.23e-242 - - - S - - - TerB-C domain
NEHAAAKM_01702 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NEHAAAKM_01703 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NEHAAAKM_01704 6.94e-202 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_01705 9.05e-78 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
NEHAAAKM_01706 3.36e-42 - - - - - - - -
NEHAAAKM_01707 1.78e-100 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEHAAAKM_01708 5.26e-36 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEHAAAKM_01709 2.7e-277 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NEHAAAKM_01710 5.75e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHAAAKM_01711 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEHAAAKM_01712 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NEHAAAKM_01713 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEHAAAKM_01714 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NEHAAAKM_01715 4.47e-58 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NEHAAAKM_01716 1.38e-309 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEHAAAKM_01717 7.06e-111 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NEHAAAKM_01718 2.07e-203 - - - K - - - Transcriptional regulator
NEHAAAKM_01719 1.31e-81 - - - S - - - Domain of unknown function (DUF956)
NEHAAAKM_01720 3.51e-222 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NEHAAAKM_01721 9.65e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NEHAAAKM_01722 2.72e-236 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEHAAAKM_01724 1.38e-165 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEHAAAKM_01725 9.06e-184 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEHAAAKM_01726 1.44e-53 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEHAAAKM_01727 4.98e-37 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEHAAAKM_01728 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEHAAAKM_01729 1.23e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEHAAAKM_01730 3.2e-143 - - - S - - - SNARE associated Golgi protein
NEHAAAKM_01731 2.52e-194 - - - I - - - alpha/beta hydrolase fold
NEHAAAKM_01732 1.67e-80 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NEHAAAKM_01733 4.06e-109 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NEHAAAKM_01734 9.75e-20 - - - S ko:K07133 - ko00000 cog cog1373
NEHAAAKM_01735 1.41e-37 - - - S ko:K07133 - ko00000 cog cog1373
NEHAAAKM_01736 2.35e-117 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NEHAAAKM_01737 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NEHAAAKM_01738 1.2e-220 - - - - - - - -
NEHAAAKM_01739 1.86e-31 - - - K - - - Acetyltransferase (GNAT) domain
NEHAAAKM_01741 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NEHAAAKM_01742 1.53e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
NEHAAAKM_01743 1.89e-205 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NEHAAAKM_01744 1.4e-207 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEHAAAKM_01745 1.23e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEHAAAKM_01746 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
NEHAAAKM_01747 3.25e-186 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHAAAKM_01748 1.64e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
NEHAAAKM_01749 5.26e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEHAAAKM_01750 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEHAAAKM_01751 7.24e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NEHAAAKM_01752 1.29e-230 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
NEHAAAKM_01753 5.11e-203 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NEHAAAKM_01754 2.23e-150 yviA - - S - - - Protein of unknown function (DUF421)
NEHAAAKM_01755 2.94e-74 - - - S - - - Protein of unknown function (DUF3290)
NEHAAAKM_01756 4.74e-110 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_01757 7.8e-10 - - - S - - - Protein of unknown function (DUF3290)
NEHAAAKM_01758 3.85e-180 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NEHAAAKM_01759 4.53e-11 - - - - - - - -
NEHAAAKM_01760 1.02e-75 - - - - - - - -
NEHAAAKM_01761 2.62e-69 - - - - - - - -
NEHAAAKM_01763 4.4e-165 - - - S - - - PAS domain
NEHAAAKM_01764 0.0 - - - V - - - ABC transporter transmembrane region
NEHAAAKM_01765 1.28e-228 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEHAAAKM_01766 1.75e-168 - - - T - - - Transcriptional regulatory protein, C terminal
NEHAAAKM_01767 2.37e-242 - - - T - - - GHKL domain
NEHAAAKM_01768 2.88e-98 ykoJ - - S - - - Peptidase propeptide and YPEB domain
NEHAAAKM_01769 5.59e-109 - - - S - - - Peptidase propeptide and YPEB domain
NEHAAAKM_01770 8e-108 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEHAAAKM_01771 8.64e-85 yybA - - K - - - Transcriptional regulator
NEHAAAKM_01772 2.91e-83 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NEHAAAKM_01773 1.13e-201 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NEHAAAKM_01774 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHAAAKM_01775 1.73e-79 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NEHAAAKM_01776 1.45e-36 - - - S - - - Peptidase propeptide and YPEB domain
NEHAAAKM_01777 2.15e-299 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NEHAAAKM_01778 1.24e-75 - - - S - - - Peptidase propeptide and YPEB domain
NEHAAAKM_01779 1.48e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEHAAAKM_01780 1.95e-218 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NEHAAAKM_01781 1.88e-125 - - - E - - - GDSL-like Lipase/Acylhydrolase
NEHAAAKM_01782 1.36e-96 yjcF - - S - - - Acetyltransferase (GNAT) domain
NEHAAAKM_01783 7.09e-184 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NEHAAAKM_01784 6.89e-136 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
NEHAAAKM_01785 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01786 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NEHAAAKM_01787 1.51e-150 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NEHAAAKM_01788 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
NEHAAAKM_01789 1.87e-308 - - - S - - - response to antibiotic
NEHAAAKM_01790 1.34e-162 - - - - - - - -
NEHAAAKM_01791 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEHAAAKM_01792 6.28e-87 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NEHAAAKM_01793 1.42e-57 - - - - - - - -
NEHAAAKM_01794 4.65e-14 - - - - - - - -
NEHAAAKM_01795 7.81e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
NEHAAAKM_01796 8.28e-176 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NEHAAAKM_01797 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
NEHAAAKM_01798 8.75e-197 - - - - - - - -
NEHAAAKM_01799 6.16e-14 - - - - - - - -
NEHAAAKM_01800 1.57e-61 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
NEHAAAKM_01801 6.84e-10 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
NEHAAAKM_01802 1.2e-71 - - - L - - - Phage terminase, small subunit
NEHAAAKM_01806 2.71e-49 - - - S - - - VRR_NUC
NEHAAAKM_01810 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NEHAAAKM_01811 1.67e-250 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NEHAAAKM_01814 9.92e-152 cps3J - - M - - - Domain of unknown function (DUF4422)
NEHAAAKM_01815 2.91e-140 epsE2 - - M - - - Bacterial sugar transferase
NEHAAAKM_01816 2.22e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NEHAAAKM_01817 5.61e-160 ywqD - - D - - - Capsular exopolysaccharide family
NEHAAAKM_01818 5.52e-187 epsB - - M - - - biosynthesis protein
NEHAAAKM_01819 8.14e-241 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEHAAAKM_01821 6.72e-285 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEHAAAKM_01822 1.26e-223 - - - S - - - Cysteine-rich secretory protein family
NEHAAAKM_01823 3.01e-54 - - - - - - - -
NEHAAAKM_01824 6.72e-165 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
NEHAAAKM_01825 1.28e-174 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NEHAAAKM_01826 1.47e-114 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
NEHAAAKM_01827 4.26e-115 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
NEHAAAKM_01828 4.52e-56 - - - - - - - -
NEHAAAKM_01829 0.0 - - - S - - - O-antigen ligase like membrane protein
NEHAAAKM_01830 8.77e-144 - - - - - - - -
NEHAAAKM_01831 5.48e-283 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEHAAAKM_01832 4.75e-101 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NEHAAAKM_01833 1.96e-226 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHAAAKM_01834 1.16e-101 - - - - - - - -
NEHAAAKM_01835 1.58e-143 - - - S - - - Peptidase_C39 like family
NEHAAAKM_01836 7.36e-109 - - - S - - - Threonine/Serine exporter, ThrE
NEHAAAKM_01837 1.73e-172 - - - S - - - Putative threonine/serine exporter
NEHAAAKM_01838 0.0 - - - S - - - ABC transporter
NEHAAAKM_01839 2.52e-76 - - - - - - - -
NEHAAAKM_01840 8.69e-93 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEHAAAKM_01841 5.49e-46 - - - - - - - -
NEHAAAKM_01842 7.2e-40 - - - - - - - -
NEHAAAKM_01843 2.33e-143 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NEHAAAKM_01844 5.74e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEHAAAKM_01845 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NEHAAAKM_01846 7.27e-42 - - - - - - - -
NEHAAAKM_01847 1.47e-91 doc - - S ko:K07341 - ko00000,ko02048 Prophage maintenance system killer protein
NEHAAAKM_01850 4.61e-37 - - - S - - - Enterocin A Immunity
NEHAAAKM_01853 1.13e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NEHAAAKM_01854 0.000868 - - - - - - - -
NEHAAAKM_01855 2.04e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NEHAAAKM_01856 6.6e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEHAAAKM_01857 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NEHAAAKM_01858 1.59e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NEHAAAKM_01859 1.63e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEHAAAKM_01860 9.9e-209 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEHAAAKM_01861 4.47e-56 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NEHAAAKM_01862 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NEHAAAKM_01863 2.18e-215 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NEHAAAKM_01864 3.14e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NEHAAAKM_01865 6.39e-279 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEHAAAKM_01866 3.09e-212 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01867 3.41e-88 - - - - - - - -
NEHAAAKM_01868 2.52e-32 - - - - - - - -
NEHAAAKM_01869 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NEHAAAKM_01870 4.74e-107 - - - - - - - -
NEHAAAKM_01871 7.87e-30 - - - - - - - -
NEHAAAKM_01875 5.02e-180 blpT - - - - - - -
NEHAAAKM_01876 7.86e-138 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NEHAAAKM_01877 1.85e-141 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEHAAAKM_01878 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEHAAAKM_01879 2.08e-164 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEHAAAKM_01880 8.34e-171 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEHAAAKM_01881 1.89e-23 - - - - - - - -
NEHAAAKM_01882 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
NEHAAAKM_01883 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NEHAAAKM_01884 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
NEHAAAKM_01885 4.48e-34 - - - - - - - -
NEHAAAKM_01886 1.07e-35 - - - - - - - -
NEHAAAKM_01887 1.95e-45 - - - - - - - -
NEHAAAKM_01888 6.94e-70 - - - S - - - Enterocin A Immunity
NEHAAAKM_01889 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NEHAAAKM_01890 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEHAAAKM_01891 9.28e-271 - - - T - - - His Kinase A (phosphoacceptor) domain
NEHAAAKM_01892 8.32e-157 vanR - - K - - - response regulator
NEHAAAKM_01894 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEHAAAKM_01895 1.68e-179 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01896 1.22e-190 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01897 3.93e-176 - - - S - - - Protein of unknown function (DUF1129)
NEHAAAKM_01898 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEHAAAKM_01899 1.1e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NEHAAAKM_01900 1.49e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEHAAAKM_01901 4.99e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NEHAAAKM_01902 1.18e-190 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEHAAAKM_01903 3.66e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NEHAAAKM_01904 2.99e-75 cvpA - - S - - - Colicin V production protein
NEHAAAKM_01906 5.24e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEHAAAKM_01907 9.48e-194 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEHAAAKM_01908 2.58e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NEHAAAKM_01909 3.41e-125 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NEHAAAKM_01910 1.25e-143 - - - K - - - WHG domain
NEHAAAKM_01911 2.63e-50 - - - - - - - -
NEHAAAKM_01912 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEHAAAKM_01913 1.23e-131 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01914 1.05e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01915 1.45e-119 - - - K - - - Bacterial regulatory proteins, tetR family
NEHAAAKM_01916 2.75e-143 - - - G - - - phosphoglycerate mutase
NEHAAAKM_01917 9.79e-181 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
NEHAAAKM_01918 1.45e-183 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NEHAAAKM_01919 5.5e-155 - - - - - - - -
NEHAAAKM_01920 9.18e-202 - - - C - - - Domain of unknown function (DUF4931)
NEHAAAKM_01921 3.58e-251 - - - S - - - Putative peptidoglycan binding domain
NEHAAAKM_01922 2.61e-23 - - - - - - - -
NEHAAAKM_01923 3.15e-121 - - - S - - - membrane
NEHAAAKM_01924 5.3e-92 - - - K - - - LytTr DNA-binding domain
NEHAAAKM_01925 6.93e-34 - - - S - - - Sugar efflux transporter for intercellular exchange
NEHAAAKM_01926 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NEHAAAKM_01927 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NEHAAAKM_01928 2.2e-79 lysM - - M - - - LysM domain
NEHAAAKM_01929 7.62e-223 - - - - - - - -
NEHAAAKM_01930 6.74e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NEHAAAKM_01931 1.27e-58 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NEHAAAKM_01935 4.73e-84 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_01936 1.39e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01937 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHAAAKM_01938 2.73e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEHAAAKM_01939 2.85e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHAAAKM_01940 7.7e-149 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NEHAAAKM_01941 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NEHAAAKM_01942 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NEHAAAKM_01943 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NEHAAAKM_01944 0.0 - - - M - - - Rib/alpha-like repeat
NEHAAAKM_01945 6.36e-230 yvdE - - K - - - helix_turn _helix lactose operon repressor
NEHAAAKM_01946 4.24e-46 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEHAAAKM_01947 4.23e-46 - - - L - - - An automated process has identified a potential problem with this gene model
NEHAAAKM_01948 1e-131 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEHAAAKM_01949 1.11e-244 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEHAAAKM_01950 6.25e-83 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEHAAAKM_01951 3.66e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NEHAAAKM_01952 1.74e-248 - - - G - - - Transmembrane secretion effector
NEHAAAKM_01953 5.63e-171 - - - V - - - ABC transporter transmembrane region
NEHAAAKM_01954 3.65e-285 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NEHAAAKM_01955 2.58e-91 - - - V - - - ABC transporter transmembrane region
NEHAAAKM_01956 6.69e-84 - - - L - - - RelB antitoxin
NEHAAAKM_01957 1.51e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NEHAAAKM_01958 8.6e-108 - - - M - - - NlpC/P60 family
NEHAAAKM_01961 1.02e-200 - - - - - - - -
NEHAAAKM_01962 1.03e-07 - - - - - - - -
NEHAAAKM_01963 5.51e-47 - - - - - - - -
NEHAAAKM_01964 4.48e-206 - - - EG - - - EamA-like transporter family
NEHAAAKM_01965 3.18e-209 - - - EG - - - EamA-like transporter family
NEHAAAKM_01966 3.75e-178 yicL - - EG - - - EamA-like transporter family
NEHAAAKM_01967 1.32e-137 - - - - - - - -
NEHAAAKM_01968 9.07e-143 - - - - - - - -
NEHAAAKM_01969 1.84e-238 - - - S - - - DUF218 domain
NEHAAAKM_01970 0.0 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
NEHAAAKM_01971 6.77e-111 - - - - - - - -
NEHAAAKM_01972 1.09e-74 - - - - - - - -
NEHAAAKM_01973 7.26e-35 - - - S - - - Protein conserved in bacteria
NEHAAAKM_01974 2.27e-71 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
NEHAAAKM_01975 1.01e-38 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
NEHAAAKM_01976 7.13e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NEHAAAKM_01977 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEHAAAKM_01978 3.87e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEHAAAKM_01981 1.84e-263 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
NEHAAAKM_01982 5.12e-242 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NEHAAAKM_01983 6.45e-291 - - - E - - - amino acid
NEHAAAKM_01984 6.65e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NEHAAAKM_01986 1.95e-221 - - - V - - - HNH endonuclease
NEHAAAKM_01987 6.36e-173 - - - S - - - PFAM Archaeal ATPase
NEHAAAKM_01988 5.27e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
NEHAAAKM_01989 2.58e-310 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEHAAAKM_01990 5.08e-149 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEHAAAKM_01991 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
NEHAAAKM_01992 7.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHAAAKM_01993 3.09e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHAAAKM_01994 1.68e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_01995 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEHAAAKM_01996 1.96e-49 - - - - - - - -
NEHAAAKM_01997 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEHAAAKM_01998 1.34e-183 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEHAAAKM_01999 2.5e-172 - - - S - - - Protein of unknown function (DUF975)
NEHAAAKM_02000 1.97e-227 pbpX2 - - V - - - Beta-lactamase
NEHAAAKM_02001 6.34e-314 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NEHAAAKM_02002 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHAAAKM_02003 2.95e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NEHAAAKM_02004 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHAAAKM_02005 1.3e-26 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NEHAAAKM_02006 1.42e-58 - - - - - - - -
NEHAAAKM_02007 5.11e-265 - - - S - - - Membrane
NEHAAAKM_02008 3.41e-107 ykuL - - S - - - (CBS) domain
NEHAAAKM_02009 0.0 cadA - - P - - - P-type ATPase
NEHAAAKM_02010 5.71e-263 napA - - P - - - Sodium/hydrogen exchanger family
NEHAAAKM_02011 2.49e-63 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
NEHAAAKM_02012 1.68e-55 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
NEHAAAKM_02013 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NEHAAAKM_02014 7.78e-200 mutR - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_02015 1.05e-67 - - - - - - - -
NEHAAAKM_02016 3.62e-202 - - - EGP - - - Major facilitator Superfamily
NEHAAAKM_02017 1.49e-141 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
NEHAAAKM_02018 3.43e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHAAAKM_02019 5.14e-248 - - - S - - - DUF218 domain
NEHAAAKM_02020 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_02021 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NEHAAAKM_02022 5.9e-130 - - - S - - - ECF transporter, substrate-specific component
NEHAAAKM_02023 1.97e-255 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
NEHAAAKM_02024 4.57e-232 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
NEHAAAKM_02025 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
NEHAAAKM_02026 8.8e-262 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEHAAAKM_02027 2.1e-220 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEHAAAKM_02028 3.08e-205 - - - S - - - Aldo/keto reductase family
NEHAAAKM_02029 1.15e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEHAAAKM_02030 9.85e-154 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NEHAAAKM_02031 1.06e-159 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NEHAAAKM_02032 6.64e-94 - - - - - - - -
NEHAAAKM_02033 2.56e-179 - - - S - - - haloacid dehalogenase-like hydrolase
NEHAAAKM_02034 9.69e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NEHAAAKM_02035 3.85e-97 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEHAAAKM_02036 4.03e-75 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEHAAAKM_02037 8.34e-116 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHAAAKM_02038 1.64e-45 - - - - - - - -
NEHAAAKM_02039 3.31e-154 - - - K - - - helix_turn_helix, mercury resistance
NEHAAAKM_02040 3.82e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NEHAAAKM_02041 4.59e-17 - - - K - - - Helix-turn-helix domain
NEHAAAKM_02042 5.94e-75 - - - S - - - Cupredoxin-like domain
NEHAAAKM_02043 3.27e-58 - - - S - - - Cupredoxin-like domain
NEHAAAKM_02044 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NEHAAAKM_02045 6.63e-147 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
NEHAAAKM_02046 3.14e-137 - - - - - - - -
NEHAAAKM_02047 1.3e-247 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
NEHAAAKM_02048 6.46e-27 - - - - - - - -
NEHAAAKM_02049 3.91e-269 - - - - - - - -
NEHAAAKM_02050 6.57e-175 - - - S - - - SLAP domain
NEHAAAKM_02051 1.14e-154 - - - S - - - SLAP domain
NEHAAAKM_02052 4.54e-135 - - - S - - - Bacteriocin helveticin-J
NEHAAAKM_02053 2.35e-58 - - - - - - - -
NEHAAAKM_02054 8.29e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_02055 1.98e-41 - - - E - - - Zn peptidase
NEHAAAKM_02056 0.0 eriC - - P ko:K03281 - ko00000 chloride
NEHAAAKM_02057 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEHAAAKM_02058 5.38e-39 - - - - - - - -
NEHAAAKM_02059 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEHAAAKM_02060 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEHAAAKM_02061 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEHAAAKM_02062 5.58e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEHAAAKM_02063 1.87e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEHAAAKM_02064 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NEHAAAKM_02065 1.92e-315 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEHAAAKM_02066 1.05e-240 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEHAAAKM_02067 1.18e-95 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
NEHAAAKM_02069 5.89e-316 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
NEHAAAKM_02070 1.22e-195 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHAAAKM_02071 4.48e-174 potA11 3.6.3.30 - P ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NEHAAAKM_02072 7.05e-146 potC3 - - E ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHAAAKM_02073 5.34e-77 tnpR1 - - L - - - Resolvase, N terminal domain
NEHAAAKM_02074 4.1e-34 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NEHAAAKM_02075 7.44e-129 - - - L - - - An automated process has identified a potential problem with this gene model
NEHAAAKM_02076 5.44e-161 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NEHAAAKM_02077 5.48e-103 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEHAAAKM_02078 7.88e-59 - - - L - - - Transposase, IS116 IS110 IS902 family
NEHAAAKM_02079 1.89e-32 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_02080 2.5e-136 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NEHAAAKM_02081 2.22e-113 - - - L - - - Belongs to the 'phage' integrase family
NEHAAAKM_02083 7.72e-09 - - - M - - - Host cell surface-exposed lipoprotein
NEHAAAKM_02085 3.24e-24 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_02086 2.18e-24 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_02087 1.38e-121 - - - S - - - DNA binding
NEHAAAKM_02093 4.49e-42 - - - S - - - Helix-turn-helix domain
NEHAAAKM_02094 2.12e-24 - - - - - - - -
NEHAAAKM_02096 1.07e-58 - - - - - - - -
NEHAAAKM_02097 3.17e-161 - - - S - - - Protein of unknown function (DUF1351)
NEHAAAKM_02098 5.44e-168 - - - S - - - ERF superfamily
NEHAAAKM_02099 4.02e-140 - - - L - - - Helix-turn-helix domain
NEHAAAKM_02107 1.32e-273 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
NEHAAAKM_02113 2.21e-13 - - - L ko:K07474 - ko00000 Terminase small subunit
NEHAAAKM_02114 9.67e-251 - - - S - - - Terminase-like family
NEHAAAKM_02115 4.77e-165 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
NEHAAAKM_02116 7.9e-55 - - - S - - - Phage Mu protein F like protein
NEHAAAKM_02118 1.1e-83 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
NEHAAAKM_02120 5.88e-118 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2184)
NEHAAAKM_02122 5.06e-33 - - - - - - - -
NEHAAAKM_02123 5.58e-34 - - - - - - - -
NEHAAAKM_02125 4.55e-127 - - - S - - - Protein of unknown function (DUF3383)
NEHAAAKM_02126 5.24e-38 - - - - - - - -
NEHAAAKM_02129 3.88e-276 - - - L - - - Phage tail tape measure protein TP901
NEHAAAKM_02130 7.64e-54 - - - M - - - LysM domain
NEHAAAKM_02131 9.82e-61 - - - - - - - -
NEHAAAKM_02132 1.87e-127 - - - - - - - -
NEHAAAKM_02133 9.53e-48 - - - - - - - -
NEHAAAKM_02134 6.21e-38 - - - - - - - -
NEHAAAKM_02135 3.34e-139 - - - S - - - Baseplate J-like protein
NEHAAAKM_02138 2.95e-92 - - - - - - - -
NEHAAAKM_02144 1.58e-09 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
NEHAAAKM_02147 1.28e-22 - - - - - - - -
NEHAAAKM_02148 1.66e-36 - - - - - - - -
NEHAAAKM_02149 2e-232 - - - M - - - Glycosyl hydrolases family 25
NEHAAAKM_02151 4.47e-26 - - - - - - - -
NEHAAAKM_02152 3.01e-92 pct 2.8.3.1 - I ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 ko00000,ko00001,ko01000 Coenzyme A transferase
NEHAAAKM_02153 4.12e-205 pct 2.8.3.1 - I ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 ko00000,ko00001,ko01000 Coenzyme A transferase
NEHAAAKM_02154 5.38e-184 - - - K - - - LysR substrate binding domain
NEHAAAKM_02155 1.47e-70 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEHAAAKM_02156 1.41e-97 - - - S - - - ECF transporter, substrate-specific component
NEHAAAKM_02157 3.28e-101 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NEHAAAKM_02158 1.29e-41 - - - O - - - OsmC-like protein
NEHAAAKM_02160 1.33e-44 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEHAAAKM_02161 2.15e-84 - - - L - - - An automated process has identified a potential problem with this gene model
NEHAAAKM_02162 2.97e-56 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEHAAAKM_02163 1.9e-158 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NEHAAAKM_02164 2.42e-163 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NEHAAAKM_02165 4.9e-180 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEHAAAKM_02166 3.44e-300 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NEHAAAKM_02167 7.28e-80 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NEHAAAKM_02168 3.17e-67 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEHAAAKM_02169 2.53e-268 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEHAAAKM_02170 1.4e-137 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NEHAAAKM_02171 2.77e-177 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NEHAAAKM_02172 4.22e-41 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEHAAAKM_02173 1.98e-47 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEHAAAKM_02174 9.89e-112 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEHAAAKM_02175 8.44e-65 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NEHAAAKM_02176 1.67e-95 - - - K - - - Transcriptional regulator, MarR family
NEHAAAKM_02177 6.14e-107 - - - - - - - -
NEHAAAKM_02178 3.76e-18 - - - K - - - Acetyltransferase (GNAT) domain
NEHAAAKM_02179 7.51e-16 - - - L - - - Transposase
NEHAAAKM_02180 1.01e-22 - - - L - - - Transposase
NEHAAAKM_02181 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NEHAAAKM_02182 5.85e-86 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NEHAAAKM_02183 1.52e-157 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NEHAAAKM_02184 1.78e-163 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
NEHAAAKM_02185 2.85e-115 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
NEHAAAKM_02186 4.82e-42 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEHAAAKM_02187 6.58e-293 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEHAAAKM_02188 4.93e-80 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHAAAKM_02189 6.33e-221 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
NEHAAAKM_02191 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
NEHAAAKM_02192 4.62e-25 - - - S - - - Protein of unknown function (DUF669)
NEHAAAKM_02193 1.52e-182 - - - L - - - Helicase C-terminal domain protein
NEHAAAKM_02195 8.83e-88 - - - S - - - AAA domain
NEHAAAKM_02201 5.99e-61 - - - - - - - -
NEHAAAKM_02202 1.23e-101 - - - S - - - Phage antirepressor protein KilAC domain
NEHAAAKM_02203 2.69e-25 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_02204 2.15e-09 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHAAAKM_02207 1.27e-311 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEHAAAKM_02208 1.64e-59 yitW - - S - - - Iron-sulfur cluster assembly protein
NEHAAAKM_02209 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NEHAAAKM_02210 6.98e-78 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NEHAAAKM_02211 1.39e-224 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEHAAAKM_02212 6.22e-232 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NEHAAAKM_02213 4.43e-179 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NEHAAAKM_02214 1.08e-161 - - - S ko:K07133 - ko00000 cog cog1373
NEHAAAKM_02215 1.48e-139 - - - EGP - - - Major Facilitator
NEHAAAKM_02216 9.16e-301 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NEHAAAKM_02217 7.84e-95 - - - EGP - - - Major Facilitator
NEHAAAKM_02218 2.58e-45 - - - - - - - -
NEHAAAKM_02220 3.3e-42 - - - - - - - -
NEHAAAKM_02221 3.98e-97 - - - M - - - LysM domain
NEHAAAKM_02222 1.61e-145 - - - L - - - UvrD/REP helicase N-terminal domain
NEHAAAKM_02223 6.82e-154 - - - L ko:K07459 - ko00000 AAA ATPase domain
NEHAAAKM_02224 1.15e-32 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEHAAAKM_02226 3.3e-203 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NEHAAAKM_02227 7.13e-67 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NEHAAAKM_02228 1.53e-189 - 5.2.1.13 - Q ko:K09835 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
NEHAAAKM_02229 3.43e-79 - - - C - - - 2Fe-2S iron-sulfur cluster binding domain
NEHAAAKM_02230 2.52e-06 - - - D - - - Domain of Unknown Function (DUF1542)
NEHAAAKM_02231 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
NEHAAAKM_02232 4.97e-45 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537,ko:K12952 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
NEHAAAKM_02235 1.71e-72 - - - S - - - Phage terminase, small subunit
NEHAAAKM_02236 1.34e-62 - - - L - - - HNH nucleases
NEHAAAKM_02241 3.85e-49 - - - S - - - VRR_NUC
NEHAAAKM_02244 9.07e-51 - - - S - - - CRISPR-associated protein (Cas_Csn2)
NEHAAAKM_02245 4.67e-54 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEHAAAKM_02246 1.44e-164 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEHAAAKM_02247 2.47e-104 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NEHAAAKM_02248 1.5e-93 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NEHAAAKM_02249 3.27e-23 - - - - - - - -
NEHAAAKM_02250 3.26e-57 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NEHAAAKM_02251 4.28e-42 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NEHAAAKM_02256 4.63e-250 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
NEHAAAKM_02258 8.3e-68 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHAAAKM_02259 4.63e-32 - - - - - - - -
NEHAAAKM_02260 6.72e-177 - - - EP - - - Plasmid replication protein
NEHAAAKM_02261 1.93e-100 - - - S - - - helix_turn_helix, Deoxyribose operon repressor
NEHAAAKM_02262 4.45e-42 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NEHAAAKM_02265 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NEHAAAKM_02266 3.82e-103 epsIIG 1.1.1.133 - S ko:K00067,ko:K07011 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Glycosyltransferase, group 2 family protein
NEHAAAKM_02267 1.81e-91 - - - M - - - Glycosyltransferase, group 1 family protein
NEHAAAKM_02268 1.63e-52 - - - M - - - Glycosyl transferase family 2
NEHAAAKM_02270 4.4e-86 - - - K - - - LytTr DNA-binding domain
NEHAAAKM_02271 6.11e-66 - - - S - - - Protein of unknown function (DUF3021)
NEHAAAKM_02272 1.25e-248 - - - K - - - IrrE N-terminal-like domain
NEHAAAKM_02273 5.88e-63 - - - - - - - -
NEHAAAKM_02274 2.14e-103 - - - - - - - -
NEHAAAKM_02275 3.39e-88 - - - S ko:K06915 - ko00000 cog cog0433
NEHAAAKM_02283 6.59e-296 - - - L - - - Transposase DDE domain
NEHAAAKM_02284 1.08e-229 - - - L - - - DDE superfamily endonuclease
NEHAAAKM_02285 9.13e-157 - - - L - - - PFAM transposase IS116 IS110 IS902
NEHAAAKM_02286 5.71e-218 - - - S - - - Uncharacterised protein family (UPF0236)
NEHAAAKM_02287 2.09e-105 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NEHAAAKM_02288 1.03e-141 - - - L - - - COG3547 Transposase and inactivated derivatives

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)