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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MAPKKHNH_00001	1.92e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAPKKHNH_00002	1.05e-240	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MAPKKHNH_00003	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MAPKKHNH_00004	5.14e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAPKKHNH_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAPKKHNH_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAPKKHNH_00007	2.74e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MAPKKHNH_00008	4.83e-104	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAPKKHNH_00009	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MAPKKHNH_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MAPKKHNH_00011	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MAPKKHNH_00012	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MAPKKHNH_00013	5.56e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
MAPKKHNH_00014	2.26e-215	degV1	-	-	S	-	-	-	DegV family
MAPKKHNH_00015	1.23e-170	-	-	-	V	-	-	-	ABC transporter transmembrane region
MAPKKHNH_00016	4.76e-213	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MAPKKHNH_00017	3.81e-18	-	-	-	S	-	-	-	CsbD-like
MAPKKHNH_00018	2.26e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
MAPKKHNH_00019	1.37e-287	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MAPKKHNH_00020	3.92e-153	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MAPKKHNH_00024	2.09e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_00025	1.25e-94	-	-	-	K	-	-	-	Helix-turn-helix domain
MAPKKHNH_00027	6.66e-27	-	-	-	S	-	-	-	CAAX protease self-immunity
MAPKKHNH_00028	2.67e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MAPKKHNH_00030	4.11e-124	potE	-	-	E	-	-	-	thought to be involved in transport amino acids across the membrane
MAPKKHNH_00032	3.17e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MAPKKHNH_00034	5.61e-38	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAPKKHNH_00035	1.71e-128	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAPKKHNH_00036	1.09e-148	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MAPKKHNH_00037	3.26e-292	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_00038	3e-118	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_00039	2.54e-225	ydbI	-	-	K	-	-	-	AI-2E family transporter
MAPKKHNH_00040	1.95e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MAPKKHNH_00041	2.55e-26	-	-	-	-	-	-	-	-
MAPKKHNH_00042	1.06e-311	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MAPKKHNH_00043	2.81e-102	-	-	-	E	-	-	-	Zn peptidase
MAPKKHNH_00044	1.53e-54	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_00045	7.61e-59	-	-	-	-	-	-	-	-
MAPKKHNH_00046	1.08e-79	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MAPKKHNH_00047	3.56e-85	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_00048	8.58e-60	-	-	-	-	-	-	-	-
MAPKKHNH_00049	8.64e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_00050	4.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MAPKKHNH_00051	3.35e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MAPKKHNH_00052	7.75e-170	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MAPKKHNH_00053	7.93e-63	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MAPKKHNH_00054	5.49e-97	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MAPKKHNH_00055	9.52e-205	yvgN	-	-	C	-	-	-	Aldo keto reductase
MAPKKHNH_00056	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MAPKKHNH_00057	9.36e-85	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MAPKKHNH_00058	2.49e-54	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MAPKKHNH_00059	3.74e-180	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAPKKHNH_00060	9.62e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAPKKHNH_00061	6.37e-08	-	-	-	S	-	-	-	YSIRK type signal peptide
MAPKKHNH_00064	5.73e-201	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MAPKKHNH_00065	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MAPKKHNH_00066	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAPKKHNH_00067	6.72e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
MAPKKHNH_00068	1.05e-289	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MAPKKHNH_00069	4.19e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MAPKKHNH_00071	3.11e-13	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MAPKKHNH_00072	1.38e-107	-	-	-	J	-	-	-	FR47-like protein
MAPKKHNH_00073	3.37e-50	-	-	-	S	-	-	-	Cytochrome B5
MAPKKHNH_00074	3.92e-215	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
MAPKKHNH_00075	5.48e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
MAPKKHNH_00076	1.91e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
MAPKKHNH_00077	7.23e-201	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
MAPKKHNH_00078	4.19e-192	-	-	-	I	-	-	-	Acyl-transferase
MAPKKHNH_00080	1.09e-46	-	-	-	-	-	-	-	-
MAPKKHNH_00082	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MAPKKHNH_00083	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAPKKHNH_00084	0.0	yycH	-	-	S	-	-	-	YycH protein
MAPKKHNH_00085	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
MAPKKHNH_00086	1.19e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MAPKKHNH_00087	3.17e-224	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MAPKKHNH_00088	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MAPKKHNH_00089	1.93e-32	-	-	-	G	-	-	-	Peptidase_C39 like family
MAPKKHNH_00090	2.16e-207	-	-	-	M	-	-	-	NlpC/P60 family
MAPKKHNH_00091	6.67e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
MAPKKHNH_00092	1.09e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MAPKKHNH_00093	1.19e-114	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MAPKKHNH_00094	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_00095	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MAPKKHNH_00096	6.68e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MAPKKHNH_00097	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MAPKKHNH_00098	7.23e-244	ysdE	-	-	P	-	-	-	Citrate transporter
MAPKKHNH_00099	3.34e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MAPKKHNH_00100	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MAPKKHNH_00101	9.69e-25	-	-	-	-	-	-	-	-
MAPKKHNH_00102	1.34e-09	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MAPKKHNH_00103	4.75e-239	-	-	-	M	-	-	-	Glycosyl transferase
MAPKKHNH_00104	3.67e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MAPKKHNH_00105	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MAPKKHNH_00106	2.42e-204	-	-	-	L	-	-	-	HNH nucleases
MAPKKHNH_00107	1.4e-191	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MAPKKHNH_00108	2.89e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_00109	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAPKKHNH_00110	4.04e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MAPKKHNH_00111	7.63e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MAPKKHNH_00112	1.14e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
MAPKKHNH_00113	1.25e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MAPKKHNH_00114	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MAPKKHNH_00115	2.29e-112	-	-	-	-	-	-	-	-
MAPKKHNH_00116	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAPKKHNH_00117	1.24e-232	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MAPKKHNH_00118	5.07e-190	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAPKKHNH_00119	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MAPKKHNH_00120	2.62e-199	epsV	-	-	S	-	-	-	glycosyl transferase family 2
MAPKKHNH_00121	5.29e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MAPKKHNH_00122	3.49e-50	-	-	-	-	-	-	-	-
MAPKKHNH_00123	1.76e-233	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAPKKHNH_00124	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAPKKHNH_00125	1.11e-177	-	-	-	-	-	-	-	-
MAPKKHNH_00126	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAPKKHNH_00127	1.01e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_00128	7.36e-291	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MAPKKHNH_00129	2.43e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MAPKKHNH_00130	2.45e-164	-	-	-	-	-	-	-	-
MAPKKHNH_00131	6.89e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MAPKKHNH_00132	2.23e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MAPKKHNH_00133	4.67e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAPKKHNH_00134	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MAPKKHNH_00135	3.75e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MAPKKHNH_00137	1.14e-115	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MAPKKHNH_00138	7.6e-113	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MAPKKHNH_00139	3.56e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MAPKKHNH_00140	2.65e-108	usp5	-	-	T	-	-	-	universal stress protein
MAPKKHNH_00142	1.78e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MAPKKHNH_00143	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MAPKKHNH_00144	1.91e-168	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAPKKHNH_00145	1.29e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAPKKHNH_00146	7.05e-103	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MAPKKHNH_00147	1.87e-220	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MAPKKHNH_00148	5.61e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MAPKKHNH_00149	5.18e-109	-	-	-	-	-	-	-	-
MAPKKHNH_00150	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAPKKHNH_00151	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MAPKKHNH_00152	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MAPKKHNH_00153	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MAPKKHNH_00154	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MAPKKHNH_00155	1.69e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MAPKKHNH_00156	2.19e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MAPKKHNH_00157	5.67e-278	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAPKKHNH_00158	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MAPKKHNH_00159	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MAPKKHNH_00160	6.55e-97	-	-	-	-	-	-	-	-
MAPKKHNH_00161	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MAPKKHNH_00163	4.53e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MAPKKHNH_00164	3.61e-60	-	-	-	-	-	-	-	-
MAPKKHNH_00165	2.77e-25	-	-	-	-	-	-	-	-
MAPKKHNH_00166	1.21e-40	-	-	-	-	-	-	-	-
MAPKKHNH_00167	1.05e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MAPKKHNH_00168	1.8e-70	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MAPKKHNH_00170	2.96e-100	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MAPKKHNH_00171	3.41e-57	-	-	-	-	-	-	-	-
MAPKKHNH_00172	1.04e-286	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MAPKKHNH_00173	8.93e-233	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MAPKKHNH_00174	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MAPKKHNH_00175	2.47e-138	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MAPKKHNH_00176	1.68e-207	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MAPKKHNH_00177	1.98e-168	-	-	-	-	-	-	-	-
MAPKKHNH_00178	1.72e-149	-	-	-	-	-	-	-	-
MAPKKHNH_00179	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAPKKHNH_00180	5.18e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
MAPKKHNH_00181	2.92e-258	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAPKKHNH_00182	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MAPKKHNH_00183	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MAPKKHNH_00184	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
MAPKKHNH_00185	7.03e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MAPKKHNH_00186	9.39e-71	-	-	-	-	-	-	-	-
MAPKKHNH_00188	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MAPKKHNH_00189	1.77e-157	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAPKKHNH_00190	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAPKKHNH_00191	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAPKKHNH_00192	1.08e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MAPKKHNH_00193	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAPKKHNH_00194	6.71e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAPKKHNH_00195	3.52e-252	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MAPKKHNH_00196	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MAPKKHNH_00197	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MAPKKHNH_00198	8.35e-94	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MAPKKHNH_00199	2.02e-38	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAPKKHNH_00200	1.67e-143	-	-	-	-	-	-	-	-
MAPKKHNH_00202	1.66e-143	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
MAPKKHNH_00203	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MAPKKHNH_00204	4.29e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
MAPKKHNH_00205	4.57e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
MAPKKHNH_00206	1.28e-172	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MAPKKHNH_00207	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MAPKKHNH_00208	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAPKKHNH_00209	2.72e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MAPKKHNH_00210	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MAPKKHNH_00211	2.56e-193	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MAPKKHNH_00212	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MAPKKHNH_00213	2.91e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MAPKKHNH_00214	3.12e-308	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MAPKKHNH_00215	5.52e-113	-	-	-	-	-	-	-	-
MAPKKHNH_00216	0.0	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_00217	5.4e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAPKKHNH_00218	1.37e-219	-	-	-	GK	-	-	-	ROK family
MAPKKHNH_00219	2.53e-56	-	-	-	-	-	-	-	-
MAPKKHNH_00220	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAPKKHNH_00221	1.75e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MAPKKHNH_00222	2.38e-88	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MAPKKHNH_00223	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MAPKKHNH_00224	1.89e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAPKKHNH_00225	7.28e-97	-	-	-	K	-	-	-	acetyltransferase
MAPKKHNH_00226	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAPKKHNH_00227	2.07e-196	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
MAPKKHNH_00228	7.15e-295	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MAPKKHNH_00229	7.92e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MAPKKHNH_00230	4.63e-38	-	-	-	K	-	-	-	Helix-turn-helix
MAPKKHNH_00231	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MAPKKHNH_00232	7.01e-207	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
MAPKKHNH_00233	4.61e-304	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
MAPKKHNH_00234	2.13e-53	-	-	-	-	-	-	-	-
MAPKKHNH_00236	5.2e-119	-	-	-	D	-	-	-	ftsk spoiiie
MAPKKHNH_00237	1.01e-202	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAPKKHNH_00238	4e-79	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MAPKKHNH_00240	7.68e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MAPKKHNH_00241	7.07e-311	-	-	-	M	-	-	-	Rib/alpha-like repeat
MAPKKHNH_00243	3.31e-65	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MAPKKHNH_00245	2.86e-169	-	-	-	L	-	-	-	Transposase and inactivated derivatives
MAPKKHNH_00246	3.74e-125	-	-	-	-	-	-	-	-
MAPKKHNH_00248	3.94e-183	-	-	-	P	-	-	-	Voltage gated chloride channel
MAPKKHNH_00249	2.83e-237	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
MAPKKHNH_00250	1.05e-69	-	-	-	-	-	-	-	-
MAPKKHNH_00251	7.17e-56	-	-	-	-	-	-	-	-
MAPKKHNH_00252	5.43e-295	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAPKKHNH_00253	0.0	-	-	-	E	-	-	-	amino acid
MAPKKHNH_00254	1.64e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MAPKKHNH_00255	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
MAPKKHNH_00256	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MAPKKHNH_00257	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MAPKKHNH_00258	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MAPKKHNH_00259	3.83e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MAPKKHNH_00260	2.68e-275	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MAPKKHNH_00261	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
MAPKKHNH_00262	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAPKKHNH_00263	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MAPKKHNH_00264	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAPKKHNH_00265	7.32e-46	yabO	-	-	J	-	-	-	S4 domain protein
MAPKKHNH_00266	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MAPKKHNH_00267	1.61e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
MAPKKHNH_00268	2.75e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MAPKKHNH_00269	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAPKKHNH_00270	3.91e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MAPKKHNH_00271	2.77e-248	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAPKKHNH_00272	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MAPKKHNH_00273	2.84e-108	-	-	-	K	-	-	-	FR47-like protein
MAPKKHNH_00278	1.92e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MAPKKHNH_00279	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAPKKHNH_00280	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAPKKHNH_00281	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAPKKHNH_00282	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MAPKKHNH_00283	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MAPKKHNH_00284	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MAPKKHNH_00285	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MAPKKHNH_00286	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MAPKKHNH_00287	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MAPKKHNH_00288	1.1e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MAPKKHNH_00289	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MAPKKHNH_00290	4.01e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MAPKKHNH_00291	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MAPKKHNH_00292	3.04e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MAPKKHNH_00293	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MAPKKHNH_00294	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MAPKKHNH_00295	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MAPKKHNH_00296	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MAPKKHNH_00297	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MAPKKHNH_00298	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MAPKKHNH_00299	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MAPKKHNH_00300	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAPKKHNH_00301	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MAPKKHNH_00302	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MAPKKHNH_00303	2.8e-72	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MAPKKHNH_00304	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MAPKKHNH_00305	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MAPKKHNH_00306	4.95e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MAPKKHNH_00307	1.25e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MAPKKHNH_00308	3.7e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MAPKKHNH_00309	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MAPKKHNH_00310	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MAPKKHNH_00311	3.44e-72	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MAPKKHNH_00312	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MAPKKHNH_00313	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAPKKHNH_00314	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MAPKKHNH_00315	5.91e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAPKKHNH_00316	5.5e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAPKKHNH_00317	5.12e-174	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAPKKHNH_00318	1.06e-185	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MAPKKHNH_00319	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MAPKKHNH_00320	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MAPKKHNH_00321	1.44e-234	-	-	-	L	-	-	-	Phage integrase family
MAPKKHNH_00322	4.4e-86	-	-	-	K	-	-	-	LytTr DNA-binding domain
MAPKKHNH_00323	6.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MAPKKHNH_00324	4.57e-135	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MAPKKHNH_00325	1.1e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MAPKKHNH_00326	2.02e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MAPKKHNH_00327	3.16e-160	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MAPKKHNH_00328	8.43e-206	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MAPKKHNH_00329	2.42e-33	-	-	-	-	-	-	-	-
MAPKKHNH_00330	9.82e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAPKKHNH_00331	2.32e-234	-	-	-	S	-	-	-	AAA domain
MAPKKHNH_00332	8.69e-66	-	-	-	-	-	-	-	-
MAPKKHNH_00333	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MAPKKHNH_00334	1.11e-69	-	-	-	-	-	-	-	-
MAPKKHNH_00335	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MAPKKHNH_00336	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAPKKHNH_00337	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAPKKHNH_00338	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MAPKKHNH_00339	2.45e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MAPKKHNH_00340	2.69e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAPKKHNH_00341	1.55e-122	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MAPKKHNH_00342	1.19e-45	-	-	-	-	-	-	-	-
MAPKKHNH_00343	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MAPKKHNH_00344	4.66e-155	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MAPKKHNH_00345	1.26e-245	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MAPKKHNH_00346	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MAPKKHNH_00347	5e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MAPKKHNH_00348	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MAPKKHNH_00349	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MAPKKHNH_00350	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MAPKKHNH_00351	1.13e-210	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MAPKKHNH_00352	2.48e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MAPKKHNH_00353	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAPKKHNH_00354	3.83e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAPKKHNH_00355	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MAPKKHNH_00356	1.61e-117	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_00358	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MAPKKHNH_00359	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MAPKKHNH_00360	9.32e-189	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
MAPKKHNH_00361	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MAPKKHNH_00362	6.15e-36	-	-	-	-	-	-	-	-
MAPKKHNH_00363	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MAPKKHNH_00364	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAPKKHNH_00365	1.12e-136	-	-	-	M	-	-	-	family 8
MAPKKHNH_00366	1.15e-47	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
MAPKKHNH_00367	6.31e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MAPKKHNH_00368	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MAPKKHNH_00369	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MAPKKHNH_00370	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MAPKKHNH_00371	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MAPKKHNH_00372	8.4e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MAPKKHNH_00373	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MAPKKHNH_00374	3.05e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MAPKKHNH_00375	4.27e-167	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MAPKKHNH_00376	8.72e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MAPKKHNH_00377	1.83e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MAPKKHNH_00378	4.59e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MAPKKHNH_00379	1.94e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAPKKHNH_00380	1.28e-311	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MAPKKHNH_00381	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
MAPKKHNH_00382	4.01e-84	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MAPKKHNH_00383	9.48e-31	-	-	-	-	-	-	-	-
MAPKKHNH_00384	3.06e-53	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MAPKKHNH_00385	6.43e-230	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MAPKKHNH_00386	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MAPKKHNH_00387	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MAPKKHNH_00388	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MAPKKHNH_00389	2.14e-234	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MAPKKHNH_00390	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MAPKKHNH_00391	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MAPKKHNH_00392	2.14e-231	-	-	-	M	-	-	-	CHAP domain
MAPKKHNH_00393	2.79e-102	-	-	-	-	-	-	-	-
MAPKKHNH_00394	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAPKKHNH_00395	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MAPKKHNH_00396	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MAPKKHNH_00397	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MAPKKHNH_00398	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MAPKKHNH_00399	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MAPKKHNH_00400	4.38e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MAPKKHNH_00401	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MAPKKHNH_00402	6.15e-268	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAPKKHNH_00403	3.16e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MAPKKHNH_00404	1.26e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MAPKKHNH_00405	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MAPKKHNH_00406	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MAPKKHNH_00407	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAPKKHNH_00408	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MAPKKHNH_00409	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MAPKKHNH_00410	5.37e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAPKKHNH_00411	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MAPKKHNH_00412	5.88e-91	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MAPKKHNH_00413	4.13e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MAPKKHNH_00414	8.12e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MAPKKHNH_00415	1.55e-29	-	-	-	-	-	-	-	-
MAPKKHNH_00416	5.53e-147	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MAPKKHNH_00417	4.31e-175	-	-	-	-	-	-	-	-
MAPKKHNH_00418	4.52e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MAPKKHNH_00419	4.28e-187	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MAPKKHNH_00420	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MAPKKHNH_00421	3.09e-71	-	-	-	-	-	-	-	-
MAPKKHNH_00422	1.6e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MAPKKHNH_00423	1.23e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MAPKKHNH_00424	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MAPKKHNH_00425	9.89e-74	-	-	-	-	-	-	-	-
MAPKKHNH_00426	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MAPKKHNH_00427	4.25e-119	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MAPKKHNH_00428	6.38e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MAPKKHNH_00429	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MAPKKHNH_00430	6.9e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MAPKKHNH_00431	1.76e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MAPKKHNH_00459	1.72e-286	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
MAPKKHNH_00460	3.68e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MAPKKHNH_00461	5.35e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MAPKKHNH_00462	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MAPKKHNH_00463	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MAPKKHNH_00464	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MAPKKHNH_00465	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MAPKKHNH_00468	5.31e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MAPKKHNH_00471	7.29e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAPKKHNH_00472	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
MAPKKHNH_00474	1.92e-102	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MAPKKHNH_00475	3.39e-154	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MAPKKHNH_00476	1.32e-151	-	-	-	S	-	-	-	Putative esterase
MAPKKHNH_00477	2.11e-269	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MAPKKHNH_00478	7.66e-248	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MAPKKHNH_00479	3.75e-168	-	-	-	K	-	-	-	rpiR family
MAPKKHNH_00480	1.29e-27	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MAPKKHNH_00481	7.25e-309	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MAPKKHNH_00482	9.83e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MAPKKHNH_00483	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MAPKKHNH_00484	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MAPKKHNH_00485	1.76e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MAPKKHNH_00486	3.53e-170	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MAPKKHNH_00487	1.03e-206	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MAPKKHNH_00488	3.01e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MAPKKHNH_00489	1.41e-51	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAPKKHNH_00490	9.32e-109	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MAPKKHNH_00491	6.75e-216	-	-	-	K	-	-	-	LysR substrate binding domain
MAPKKHNH_00492	1.39e-156	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MAPKKHNH_00493	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MAPKKHNH_00494	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MAPKKHNH_00495	4.91e-289	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MAPKKHNH_00496	3.54e-300	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MAPKKHNH_00497	1.59e-61	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MAPKKHNH_00499	9.64e-307	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MAPKKHNH_00500	2.23e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MAPKKHNH_00501	5.6e-129	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MAPKKHNH_00502	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MAPKKHNH_00503	6.03e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MAPKKHNH_00504	8.08e-108	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MAPKKHNH_00505	1.32e-105	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MAPKKHNH_00506	7.02e-36	-	-	-	-	-	-	-	-
MAPKKHNH_00507	1.01e-98	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MAPKKHNH_00508	6.24e-210	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_00510	1.86e-91	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MAPKKHNH_00511	1.28e-226	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MAPKKHNH_00512	4.77e-248	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MAPKKHNH_00513	4.95e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MAPKKHNH_00514	2.74e-06	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MAPKKHNH_00515	5.46e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MAPKKHNH_00516	7.62e-134	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MAPKKHNH_00517	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MAPKKHNH_00518	1.21e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MAPKKHNH_00519	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MAPKKHNH_00520	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MAPKKHNH_00521	1.68e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MAPKKHNH_00522	0.0	yhaN	-	-	L	-	-	-	AAA domain
MAPKKHNH_00523	4.53e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAPKKHNH_00525	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
MAPKKHNH_00526	0.0	-	-	-	-	-	-	-	-
MAPKKHNH_00527	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
MAPKKHNH_00528	3.12e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MAPKKHNH_00529	1.2e-41	-	-	-	-	-	-	-	-
MAPKKHNH_00530	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MAPKKHNH_00531	3.67e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_00532	1.63e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MAPKKHNH_00533	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MAPKKHNH_00535	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
MAPKKHNH_00536	8.78e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAPKKHNH_00537	2.59e-313	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MAPKKHNH_00538	4.65e-278	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MAPKKHNH_00539	2.04e-226	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_00540	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
MAPKKHNH_00541	2.43e-239	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MAPKKHNH_00542	1.33e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MAPKKHNH_00543	2.53e-139	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MAPKKHNH_00544	1.98e-35	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MAPKKHNH_00545	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MAPKKHNH_00546	7.81e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MAPKKHNH_00547	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MAPKKHNH_00548	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MAPKKHNH_00549	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
MAPKKHNH_00550	1.31e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MAPKKHNH_00551	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAPKKHNH_00552	2.28e-97	-	-	-	-	-	-	-	-
MAPKKHNH_00553	4.78e-261	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
MAPKKHNH_00554	1.53e-122	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAPKKHNH_00555	6.49e-137	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAPKKHNH_00558	8.95e-70	-	-	-	K	-	-	-	LytTr DNA-binding domain
MAPKKHNH_00559	9.29e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MAPKKHNH_00560	1.08e-217	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MAPKKHNH_00561	5.16e-118	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
MAPKKHNH_00562	5.89e-316	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
MAPKKHNH_00563	1.22e-195	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAPKKHNH_00564	2.72e-175	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MAPKKHNH_00565	7.05e-146	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAPKKHNH_00566	3.77e-131	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAPKKHNH_00567	6.18e-123	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MAPKKHNH_00568	1.07e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MAPKKHNH_00569	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MAPKKHNH_00570	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MAPKKHNH_00571	1.52e-193	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MAPKKHNH_00572	5.81e-253	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MAPKKHNH_00573	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MAPKKHNH_00574	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MAPKKHNH_00575	2.51e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAPKKHNH_00576	1.59e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MAPKKHNH_00577	5.09e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MAPKKHNH_00578	8.01e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MAPKKHNH_00579	2.19e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MAPKKHNH_00580	3.52e-163	csrR	-	-	K	-	-	-	response regulator
MAPKKHNH_00581	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAPKKHNH_00582	2.19e-18	-	-	-	-	-	-	-	-
MAPKKHNH_00583	5.18e-65	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAPKKHNH_00584	2.85e-25	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAPKKHNH_00585	2.95e-283	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_00586	1.13e-108	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MAPKKHNH_00587	8.13e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAPKKHNH_00588	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MAPKKHNH_00589	5.59e-173	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAPKKHNH_00590	3.71e-76	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MAPKKHNH_00592	2.9e-31	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MAPKKHNH_00593	1.11e-98	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MAPKKHNH_00594	1.68e-149	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MAPKKHNH_00595	7.91e-164	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_00596	2.82e-201	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_00597	2.9e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAPKKHNH_00598	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAPKKHNH_00599	1.72e-92	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAPKKHNH_00600	8.21e-215	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
MAPKKHNH_00601	5.5e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAPKKHNH_00602	1.8e-34	-	-	-	-	-	-	-	-
MAPKKHNH_00603	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
MAPKKHNH_00604	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MAPKKHNH_00605	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAPKKHNH_00606	2.77e-292	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MAPKKHNH_00607	5.84e-312	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
MAPKKHNH_00608	1.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
MAPKKHNH_00609	2.04e-60	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_00610	6.91e-67	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MAPKKHNH_00611	1.29e-164	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_00612	6.09e-121	-	-	-	-	-	-	-	-
MAPKKHNH_00614	7.04e-159	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
MAPKKHNH_00615	2.07e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MAPKKHNH_00616	1.55e-201	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAPKKHNH_00617	1.49e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
MAPKKHNH_00618	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAPKKHNH_00619	2.74e-69	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MAPKKHNH_00620	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MAPKKHNH_00621	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MAPKKHNH_00622	0.0	-	-	-	S	-	-	-	membrane
MAPKKHNH_00623	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MAPKKHNH_00624	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MAPKKHNH_00625	7.92e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MAPKKHNH_00626	3.25e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MAPKKHNH_00627	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MAPKKHNH_00628	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MAPKKHNH_00629	9.03e-215	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAPKKHNH_00630	2.05e-286	ynbB	-	-	P	-	-	-	aluminum resistance
MAPKKHNH_00631	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MAPKKHNH_00632	2.37e-219	-	-	-	-	-	-	-	-
MAPKKHNH_00633	2.09e-205	-	-	-	-	-	-	-	-
MAPKKHNH_00637	6.78e-47	-	-	-	-	-	-	-	-
MAPKKHNH_00638	1.94e-165	-	-	-	S	-	-	-	interspecies interaction between organisms
MAPKKHNH_00639	1.28e-09	-	-	-	S	-	-	-	PFAM HicB family
MAPKKHNH_00640	2.86e-13	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
MAPKKHNH_00641	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAPKKHNH_00642	1.57e-84	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MAPKKHNH_00643	2.65e-154	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MAPKKHNH_00644	1.03e-112	nanK	-	-	GK	-	-	-	ROK family
MAPKKHNH_00645	3.74e-70	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MAPKKHNH_00646	1.48e-166	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MAPKKHNH_00647	6.48e-279	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAPKKHNH_00648	1.4e-74	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MAPKKHNH_00649	4.42e-45	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MAPKKHNH_00650	6.9e-141	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MAPKKHNH_00651	2.58e-13	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MAPKKHNH_00652	1.59e-108	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MAPKKHNH_00653	3.32e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAPKKHNH_00654	2.5e-136	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
MAPKKHNH_00655	8.45e-102	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
MAPKKHNH_00656	4.12e-205	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
MAPKKHNH_00657	5.38e-184	-	-	-	K	-	-	-	LysR substrate binding domain
MAPKKHNH_00658	1.47e-70	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAPKKHNH_00659	1.41e-97	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MAPKKHNH_00660	3.28e-101	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MAPKKHNH_00661	4.05e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
MAPKKHNH_00662	5.55e-137	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
MAPKKHNH_00663	2.44e-210	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAPKKHNH_00664	2.84e-240	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MAPKKHNH_00665	5.06e-184	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MAPKKHNH_00666	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MAPKKHNH_00667	1.48e-210	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MAPKKHNH_00668	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MAPKKHNH_00669	3.37e-312	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MAPKKHNH_00670	5.06e-98	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MAPKKHNH_00671	4.16e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MAPKKHNH_00672	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MAPKKHNH_00673	1.6e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MAPKKHNH_00674	2.14e-48	-	-	-	-	-	-	-	-
MAPKKHNH_00675	6.89e-93	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MAPKKHNH_00676	4.63e-253	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MAPKKHNH_00677	3e-290	sptS	-	-	T	-	-	-	Histidine kinase
MAPKKHNH_00678	7.86e-266	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAPKKHNH_00679	1.08e-88	-	-	-	O	-	-	-	OsmC-like protein
MAPKKHNH_00680	3.89e-122	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MAPKKHNH_00681	5.57e-108	-	-	-	-	-	-	-	-
MAPKKHNH_00682	4.36e-126	-	-	-	-	-	-	-	-
MAPKKHNH_00683	1.37e-219	-	-	-	-	-	-	-	-
MAPKKHNH_00684	2.65e-107	-	-	-	S	-	-	-	Fic/DOC family
MAPKKHNH_00685	0.0	potE	-	-	E	-	-	-	Amino Acid
MAPKKHNH_00686	2.44e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAPKKHNH_00687	8.62e-311	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MAPKKHNH_00688	1.68e-64	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MAPKKHNH_00689	5.01e-150	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MAPKKHNH_00690	6.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MAPKKHNH_00691	7.73e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MAPKKHNH_00692	9.46e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MAPKKHNH_00693	3.23e-59	-	-	-	-	-	-	-	-
MAPKKHNH_00694	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MAPKKHNH_00695	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
MAPKKHNH_00696	4.14e-113	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MAPKKHNH_00698	5.32e-42	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
MAPKKHNH_00699	4.02e-91	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
MAPKKHNH_00700	9e-132	-	-	-	L	-	-	-	Integrase
MAPKKHNH_00701	1.48e-136	-	-	-	L	-	-	-	PFAM Integrase catalytic
MAPKKHNH_00702	2.28e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAPKKHNH_00703	2.99e-07	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAPKKHNH_00704	5.93e-50	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAPKKHNH_00705	6.55e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAPKKHNH_00706	1.45e-34	-	-	-	K	-	-	-	FCD
MAPKKHNH_00707	4.3e-13	-	-	-	K	-	-	-	FCD
MAPKKHNH_00708	4.37e-132	-	-	-	GM	-	-	-	NmrA-like family
MAPKKHNH_00709	5.5e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MAPKKHNH_00710	1.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MAPKKHNH_00711	8.81e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MAPKKHNH_00712	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MAPKKHNH_00713	3.68e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MAPKKHNH_00714	8.31e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MAPKKHNH_00715	4.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MAPKKHNH_00716	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MAPKKHNH_00717	1.42e-197	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MAPKKHNH_00718	1.4e-103	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MAPKKHNH_00719	6.79e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MAPKKHNH_00720	8.74e-62	-	-	-	-	-	-	-	-
MAPKKHNH_00721	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MAPKKHNH_00722	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MAPKKHNH_00723	6.78e-24	-	-	-	S	-	-	-	Alpha beta hydrolase
MAPKKHNH_00724	2.48e-80	-	-	-	S	-	-	-	Alpha beta hydrolase
MAPKKHNH_00725	8.51e-50	-	-	-	-	-	-	-	-
MAPKKHNH_00726	4.3e-66	-	-	-	-	-	-	-	-
MAPKKHNH_00727	1.14e-189	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MAPKKHNH_00728	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MAPKKHNH_00729	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MAPKKHNH_00730	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MAPKKHNH_00731	1.23e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
MAPKKHNH_00733	1.16e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MAPKKHNH_00734	8.21e-200	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MAPKKHNH_00735	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MAPKKHNH_00736	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MAPKKHNH_00738	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MAPKKHNH_00739	5.24e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MAPKKHNH_00740	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MAPKKHNH_00741	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MAPKKHNH_00742	2.14e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MAPKKHNH_00743	8.59e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAPKKHNH_00744	7.98e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MAPKKHNH_00745	2.78e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MAPKKHNH_00746	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAPKKHNH_00747	1.97e-248	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAPKKHNH_00748	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAPKKHNH_00749	6.44e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MAPKKHNH_00750	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MAPKKHNH_00751	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MAPKKHNH_00752	2.19e-100	-	-	-	S	-	-	-	ASCH
MAPKKHNH_00753	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MAPKKHNH_00754	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MAPKKHNH_00755	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAPKKHNH_00756	1.27e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAPKKHNH_00757	7.82e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MAPKKHNH_00758	1.91e-34	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MAPKKHNH_00759	2.42e-133	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MAPKKHNH_00760	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MAPKKHNH_00761	1.71e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MAPKKHNH_00762	7.49e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MAPKKHNH_00763	1.1e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MAPKKHNH_00764	2.29e-41	-	-	-	-	-	-	-	-
MAPKKHNH_00765	8.76e-146	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAPKKHNH_00768	2.15e-09	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_00769	2.69e-25	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_00770	1.23e-101	-	-	-	S	-	-	-	Phage antirepressor protein KilAC domain
MAPKKHNH_00771	5.99e-61	-	-	-	-	-	-	-	-
MAPKKHNH_00777	8.83e-88	-	-	-	S	-	-	-	AAA domain
MAPKKHNH_00779	1.52e-182	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAPKKHNH_00780	4.62e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
MAPKKHNH_00781	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
MAPKKHNH_00785	1.2e-71	-	-	-	L	-	-	-	Phage terminase, small subunit
MAPKKHNH_00786	6.84e-10	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MAPKKHNH_00787	1.57e-61	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MAPKKHNH_00788	1.82e-260	-	-	-	S	-	-	-	Phage Terminase
MAPKKHNH_00790	2.23e-169	-	-	-	S	-	-	-	Phage portal protein
MAPKKHNH_00791	4.37e-110	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MAPKKHNH_00792	5.87e-67	-	-	-	S	-	-	-	Phage capsid family
MAPKKHNH_00800	2.66e-131	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MAPKKHNH_00802	5.6e-158	-	-	-	S	-	-	-	Phage minor structural protein
MAPKKHNH_00811	6.5e-51	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MAPKKHNH_00812	1.05e-120	-	-	-	M	-	-	-	hydrolase, family 25
MAPKKHNH_00814	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MAPKKHNH_00815	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MAPKKHNH_00816	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MAPKKHNH_00817	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MAPKKHNH_00818	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MAPKKHNH_00819	7.32e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAPKKHNH_00820	1.21e-245	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MAPKKHNH_00821	3.27e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MAPKKHNH_00822	7.92e-221	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAPKKHNH_00823	3.74e-182	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAPKKHNH_00824	3.35e-55	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_00825	2.02e-301	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_00826	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_00827	2.8e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MAPKKHNH_00828	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MAPKKHNH_00829	4.69e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MAPKKHNH_00830	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAPKKHNH_00831	1.69e-06	-	-	-	-	-	-	-	-
MAPKKHNH_00832	2.1e-31	-	-	-	-	-	-	-	-
MAPKKHNH_00833	5.41e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_00834	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MAPKKHNH_00835	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MAPKKHNH_00836	5.56e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MAPKKHNH_00837	1.34e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MAPKKHNH_00838	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MAPKKHNH_00839	2.08e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAPKKHNH_00840	1.63e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MAPKKHNH_00841	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MAPKKHNH_00842	4.96e-270	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_00843	1.15e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MAPKKHNH_00844	7.18e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MAPKKHNH_00845	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MAPKKHNH_00846	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
MAPKKHNH_00847	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MAPKKHNH_00848	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAPKKHNH_00849	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAPKKHNH_00850	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MAPKKHNH_00851	8.61e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MAPKKHNH_00852	1.65e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MAPKKHNH_00853	2.03e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MAPKKHNH_00854	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MAPKKHNH_00855	1.76e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAPKKHNH_00856	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MAPKKHNH_00857	1.22e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MAPKKHNH_00858	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MAPKKHNH_00859	3.93e-181	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MAPKKHNH_00860	6.38e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MAPKKHNH_00861	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MAPKKHNH_00862	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAPKKHNH_00863	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MAPKKHNH_00864	1.19e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MAPKKHNH_00865	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MAPKKHNH_00866	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
MAPKKHNH_00867	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MAPKKHNH_00868	1.67e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MAPKKHNH_00869	1.64e-198	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAPKKHNH_00870	5.35e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MAPKKHNH_00871	6.02e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MAPKKHNH_00872	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAPKKHNH_00873	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MAPKKHNH_00874	6.87e-277	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MAPKKHNH_00875	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MAPKKHNH_00876	1.09e-226	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAPKKHNH_00881	1.43e-57	-	-	-	K	-	-	-	Peptidase S24-like
MAPKKHNH_00882	3.96e-06	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_00885	7.64e-21	-	-	-	-	-	-	-	-
MAPKKHNH_00886	1.78e-124	-	-	-	S	-	-	-	AntA/AntB antirepressor
MAPKKHNH_00892	2.36e-08	-	-	-	K	-	-	-	DNA-binding protein
MAPKKHNH_00896	1.11e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
MAPKKHNH_00897	5.49e-39	-	-	-	S	-	-	-	Conserved phage C-terminus (Phg_2220_C)
MAPKKHNH_00898	8.93e-64	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
MAPKKHNH_00904	5.99e-52	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MAPKKHNH_00905	1.08e-10	-	-	-	-	-	-	-	-
MAPKKHNH_00914	8.27e-46	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MAPKKHNH_00915	7.69e-16	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MAPKKHNH_00916	3.6e-47	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
MAPKKHNH_00917	5.64e-290	-	-	-	S	-	-	-	Terminase-like family
MAPKKHNH_00918	5.29e-177	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
MAPKKHNH_00919	3.57e-128	-	-	-	S	-	-	-	Phage Mu protein F like protein
MAPKKHNH_00920	1.14e-16	-	-	-	S	-	-	-	Lysin motif
MAPKKHNH_00921	1.12e-136	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
MAPKKHNH_00922	3.08e-76	-	-	-	-	-	-	-	-
MAPKKHNH_00923	3.18e-182	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2184)
MAPKKHNH_00925	5.11e-95	-	-	-	-	-	-	-	-
MAPKKHNH_00926	5.73e-56	-	-	-	-	-	-	-	-
MAPKKHNH_00927	5.61e-69	-	-	-	-	-	-	-	-
MAPKKHNH_00928	1.12e-193	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
MAPKKHNH_00929	1.33e-73	-	-	-	-	-	-	-	-
MAPKKHNH_00932	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MAPKKHNH_00933	1.06e-69	-	-	-	M	-	-	-	LysM domain
MAPKKHNH_00934	6.91e-61	-	-	-	-	-	-	-	-
MAPKKHNH_00935	1.11e-128	-	-	-	-	-	-	-	-
MAPKKHNH_00936	4.6e-63	-	-	-	-	-	-	-	-
MAPKKHNH_00937	1.37e-42	-	-	-	-	-	-	-	-
MAPKKHNH_00938	2.78e-156	-	-	-	S	-	-	-	Baseplate J-like protein
MAPKKHNH_00940	8.4e-42	-	-	-	-	-	-	-	-
MAPKKHNH_00944	9.46e-58	-	-	-	-	-	-	-	-
MAPKKHNH_00945	2.12e-27	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
MAPKKHNH_00948	6.31e-27	-	-	-	-	-	-	-	-
MAPKKHNH_00949	1.76e-38	-	-	-	-	-	-	-	-
MAPKKHNH_00950	5.31e-221	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MAPKKHNH_00951	5.3e-32	-	-	-	-	-	-	-	-
MAPKKHNH_00952	9.71e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MAPKKHNH_00953	7e-131	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MAPKKHNH_00954	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MAPKKHNH_00955	1.15e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MAPKKHNH_00956	4.39e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MAPKKHNH_00958	5.01e-55	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MAPKKHNH_00959	4.97e-64	-	-	-	S	-	-	-	Metal binding domain of Ada
MAPKKHNH_00960	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MAPKKHNH_00961	3.03e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MAPKKHNH_00962	2.4e-297	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MAPKKHNH_00963	5.39e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MAPKKHNH_00964	2.01e-135	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MAPKKHNH_00965	1.76e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MAPKKHNH_00966	1.07e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
MAPKKHNH_00967	4.04e-29	-	-	-	-	-	-	-	-
MAPKKHNH_00968	6.93e-140	-	-	-	K	-	-	-	LysR substrate binding domain
MAPKKHNH_00969	1.13e-126	-	-	-	-	-	-	-	-
MAPKKHNH_00970	5.04e-154	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MAPKKHNH_00971	5.73e-153	-	-	-	-	-	-	-	-
MAPKKHNH_00972	8.93e-108	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAPKKHNH_00973	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MAPKKHNH_00974	1.15e-64	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MAPKKHNH_00975	5.51e-35	-	-	-	-	-	-	-	-
MAPKKHNH_00976	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
MAPKKHNH_00977	6.13e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
MAPKKHNH_00978	5.97e-55	-	-	-	S	-	-	-	SnoaL-like domain
MAPKKHNH_00979	0.0	-	-	-	L	-	-	-	PLD-like domain
MAPKKHNH_00980	6.83e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
MAPKKHNH_00981	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MAPKKHNH_00982	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MAPKKHNH_00983	2.95e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MAPKKHNH_00984	3.06e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MAPKKHNH_00985	5.47e-151	-	-	-	-	-	-	-	-
MAPKKHNH_00986	2.83e-205	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MAPKKHNH_00988	1.22e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAPKKHNH_00989	2e-149	-	-	-	S	-	-	-	Peptidase family M23
MAPKKHNH_00990	1.34e-22	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MAPKKHNH_00991	1.99e-198	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MAPKKHNH_00992	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MAPKKHNH_00993	1.08e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MAPKKHNH_00994	1.74e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MAPKKHNH_00995	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAPKKHNH_00996	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAPKKHNH_00997	4.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MAPKKHNH_00998	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MAPKKHNH_00999	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MAPKKHNH_01000	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MAPKKHNH_01001	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MAPKKHNH_01002	4.34e-166	-	-	-	S	-	-	-	Peptidase family M23
MAPKKHNH_01003	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MAPKKHNH_01004	2.8e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MAPKKHNH_01005	8.12e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MAPKKHNH_01006	2.86e-307	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MAPKKHNH_01007	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
MAPKKHNH_01008	1.33e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MAPKKHNH_01009	1.65e-180	-	-	-	-	-	-	-	-
MAPKKHNH_01010	2.54e-176	-	-	-	-	-	-	-	-
MAPKKHNH_01011	3.85e-193	-	-	-	-	-	-	-	-
MAPKKHNH_01012	3.49e-36	-	-	-	-	-	-	-	-
MAPKKHNH_01013	1.27e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MAPKKHNH_01014	4.01e-184	-	-	-	-	-	-	-	-
MAPKKHNH_01015	4.4e-215	-	-	-	-	-	-	-	-
MAPKKHNH_01016	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MAPKKHNH_01017	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MAPKKHNH_01018	4.87e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MAPKKHNH_01019	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MAPKKHNH_01020	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MAPKKHNH_01021	3.02e-173	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MAPKKHNH_01022	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MAPKKHNH_01023	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MAPKKHNH_01024	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MAPKKHNH_01025	1.66e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MAPKKHNH_01026	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MAPKKHNH_01027	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MAPKKHNH_01028	1.92e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MAPKKHNH_01029	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MAPKKHNH_01030	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MAPKKHNH_01031	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MAPKKHNH_01032	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MAPKKHNH_01033	1.68e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MAPKKHNH_01034	6.74e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAPKKHNH_01035	9.67e-104	-	-	-	-	-	-	-	-
MAPKKHNH_01036	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MAPKKHNH_01037	3.56e-47	-	-	-	-	-	-	-	-
MAPKKHNH_01038	4.13e-83	-	-	-	-	-	-	-	-
MAPKKHNH_01041	1.51e-159	-	-	-	-	-	-	-	-
MAPKKHNH_01042	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
MAPKKHNH_01043	1.24e-08	-	-	-	-	-	-	-	-
MAPKKHNH_01044	1.73e-48	-	-	-	-	-	-	-	-
MAPKKHNH_01045	0.0	snf	-	-	KL	-	-	-	domain protein
MAPKKHNH_01046	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MAPKKHNH_01047	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAPKKHNH_01048	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAPKKHNH_01049	1.11e-234	-	-	-	K	-	-	-	Transcriptional regulator
MAPKKHNH_01050	1.05e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MAPKKHNH_01051	1.17e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAPKKHNH_01052	5.03e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
MAPKKHNH_01053	3.35e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MAPKKHNH_01054	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MAPKKHNH_01055	1.5e-90	-	-	-	-	-	-	-	-
MAPKKHNH_01056	1.24e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MAPKKHNH_01057	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MAPKKHNH_01058	1.15e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
MAPKKHNH_01059	2.06e-88	-	-	-	-	-	-	-	-
MAPKKHNH_01060	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MAPKKHNH_01061	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MAPKKHNH_01062	4.13e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MAPKKHNH_01063	3.24e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAPKKHNH_01064	3.16e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAPKKHNH_01065	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MAPKKHNH_01066	1.61e-70	-	-	-	-	-	-	-	-
MAPKKHNH_01068	8.81e-40	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
MAPKKHNH_01069	9.86e-146	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MAPKKHNH_01070	3.39e-88	-	-	-	S	ko:K06915	-	ko00000	cog cog0433
MAPKKHNH_01072	4.81e-77	-	-	-	S	-	-	-	SIR2-like domain
MAPKKHNH_01073	2.08e-118	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MAPKKHNH_01074	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MAPKKHNH_01075	5.22e-54	-	-	-	S	-	-	-	RloB-like protein
MAPKKHNH_01076	1.35e-208	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MAPKKHNH_01077	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
MAPKKHNH_01078	0.0	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_01080	5.93e-302	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAPKKHNH_01081	1.43e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MAPKKHNH_01082	1.65e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MAPKKHNH_01084	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MAPKKHNH_01085	4.21e-129	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
MAPKKHNH_01086	2.02e-137	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MAPKKHNH_01087	9.63e-204	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MAPKKHNH_01088	1.12e-85	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MAPKKHNH_01089	6.84e-243	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
MAPKKHNH_01090	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MAPKKHNH_01091	5.74e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAPKKHNH_01092	1.87e-290	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MAPKKHNH_01093	7.89e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MAPKKHNH_01094	3.1e-127	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MAPKKHNH_01095	1.59e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
MAPKKHNH_01096	1.12e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MAPKKHNH_01097	1.12e-104	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MAPKKHNH_01098	4.87e-262	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MAPKKHNH_01099	5.94e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
MAPKKHNH_01100	2.25e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MAPKKHNH_01101	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MAPKKHNH_01102	3.6e-106	-	-	-	C	-	-	-	Flavodoxin
MAPKKHNH_01103	3.39e-45	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_01104	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MAPKKHNH_01105	4.97e-311	ynbB	-	-	P	-	-	-	aluminum resistance
MAPKKHNH_01106	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MAPKKHNH_01107	0.0	-	-	-	E	-	-	-	Amino acid permease
MAPKKHNH_01108	7.88e-121	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
MAPKKHNH_01109	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MAPKKHNH_01110	3.03e-145	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MAPKKHNH_01111	1.31e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MAPKKHNH_01112	2.95e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAPKKHNH_01113	7.64e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAPKKHNH_01114	2.15e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MAPKKHNH_01115	7.7e-126	-	-	-	L	-	-	-	Helix-turn-helix domain
MAPKKHNH_01116	4.47e-148	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MAPKKHNH_01117	1.8e-36	-	-	-	M	-	-	-	LysM domain protein
MAPKKHNH_01118	9.44e-63	-	-	-	M	-	-	-	LysM domain protein
MAPKKHNH_01119	9.11e-110	-	-	-	C	-	-	-	Aldo keto reductase
MAPKKHNH_01120	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MAPKKHNH_01121	1.4e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MAPKKHNH_01122	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MAPKKHNH_01123	2.09e-180	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MAPKKHNH_01124	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MAPKKHNH_01125	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MAPKKHNH_01126	1.5e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MAPKKHNH_01127	1e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAPKKHNH_01128	2.15e-198	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MAPKKHNH_01129	2.4e-118	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MAPKKHNH_01130	7.2e-49	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MAPKKHNH_01131	3.67e-88	-	-	-	P	-	-	-	NhaP-type Na H and K H
MAPKKHNH_01132	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MAPKKHNH_01133	1.2e-184	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MAPKKHNH_01134	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MAPKKHNH_01135	5.13e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MAPKKHNH_01136	3.86e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MAPKKHNH_01137	9.58e-112	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
MAPKKHNH_01138	1.01e-240	yagE	-	-	E	-	-	-	Amino acid permease
MAPKKHNH_01139	2.16e-193	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MAPKKHNH_01140	6.64e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
MAPKKHNH_01141	1.05e-176	-	-	-	F	-	-	-	Phosphorylase superfamily
MAPKKHNH_01142	9.82e-80	-	-	-	F	-	-	-	NUDIX domain
MAPKKHNH_01143	1.83e-103	-	-	-	S	-	-	-	AAA domain
MAPKKHNH_01144	1.5e-150	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
MAPKKHNH_01145	2.53e-171	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MAPKKHNH_01146	2.95e-123	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MAPKKHNH_01147	2e-299	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAPKKHNH_01148	1.23e-125	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MAPKKHNH_01149	4.33e-95	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MAPKKHNH_01150	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAPKKHNH_01151	5.45e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MAPKKHNH_01152	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MAPKKHNH_01153	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MAPKKHNH_01154	1.13e-41	-	-	-	M	-	-	-	Lysin motif
MAPKKHNH_01155	1.64e-143	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MAPKKHNH_01156	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MAPKKHNH_01157	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MAPKKHNH_01158	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MAPKKHNH_01159	1.13e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MAPKKHNH_01160	6.74e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MAPKKHNH_01161	1.21e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MAPKKHNH_01162	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MAPKKHNH_01163	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MAPKKHNH_01164	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MAPKKHNH_01165	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MAPKKHNH_01166	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MAPKKHNH_01167	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MAPKKHNH_01168	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MAPKKHNH_01169	1.18e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAPKKHNH_01170	6.82e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MAPKKHNH_01171	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MAPKKHNH_01172	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAPKKHNH_01173	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MAPKKHNH_01174	1.58e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MAPKKHNH_01175	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MAPKKHNH_01176	1.14e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAPKKHNH_01177	1.83e-190	yxeH	-	-	S	-	-	-	hydrolase
MAPKKHNH_01178	6.32e-41	-	-	-	S	-	-	-	reductase
MAPKKHNH_01179	2.98e-50	-	-	-	S	-	-	-	reductase
MAPKKHNH_01180	1.19e-43	-	-	-	S	-	-	-	reductase
MAPKKHNH_01181	3.82e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MAPKKHNH_01183	9.14e-283	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAPKKHNH_01184	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MAPKKHNH_01185	7.1e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MAPKKHNH_01186	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MAPKKHNH_01187	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAPKKHNH_01188	3.8e-80	-	-	-	-	-	-	-	-
MAPKKHNH_01189	4.8e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MAPKKHNH_01190	1.3e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MAPKKHNH_01191	5.26e-15	-	-	-	-	-	-	-	-
MAPKKHNH_01193	9.28e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
MAPKKHNH_01194	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
MAPKKHNH_01195	2.41e-66	-	-	-	-	-	-	-	-
MAPKKHNH_01196	7.91e-14	-	-	-	-	-	-	-	-
MAPKKHNH_01197	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
MAPKKHNH_01198	5.38e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MAPKKHNH_01199	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_01200	2.58e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
MAPKKHNH_01201	9.9e-30	-	-	-	-	-	-	-	-
MAPKKHNH_01202	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
MAPKKHNH_01203	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MAPKKHNH_01204	1.79e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MAPKKHNH_01205	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MAPKKHNH_01206	5.17e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MAPKKHNH_01207	8.46e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MAPKKHNH_01208	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MAPKKHNH_01209	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
MAPKKHNH_01210	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MAPKKHNH_01211	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAPKKHNH_01212	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAPKKHNH_01213	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MAPKKHNH_01214	3.32e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAPKKHNH_01215	3.87e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MAPKKHNH_01216	2.16e-205	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAPKKHNH_01217	4.26e-222	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MAPKKHNH_01218	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MAPKKHNH_01219	7.89e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MAPKKHNH_01220	2.99e-230	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAPKKHNH_01221	1.8e-316	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MAPKKHNH_01222	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MAPKKHNH_01223	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
MAPKKHNH_01224	6.04e-49	-	-	-	-	-	-	-	-
MAPKKHNH_01226	3.44e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MAPKKHNH_01227	7.94e-114	-	-	-	K	-	-	-	GNAT family
MAPKKHNH_01228	1.76e-256	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
MAPKKHNH_01230	1.23e-81	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MAPKKHNH_01231	2.69e-124	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
MAPKKHNH_01232	1.76e-135	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
MAPKKHNH_01233	9.35e-63	-	-	-	-	-	-	-	-
MAPKKHNH_01234	3.77e-86	-	-	-	K	-	-	-	HxlR family
MAPKKHNH_01235	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MAPKKHNH_01236	1.28e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MAPKKHNH_01237	1.07e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MAPKKHNH_01238	2.89e-140	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
MAPKKHNH_01239	1.34e-34	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAPKKHNH_01240	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MAPKKHNH_01241	3.46e-32	-	-	-	S	-	-	-	Alpha beta hydrolase
MAPKKHNH_01242	1.47e-303	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MAPKKHNH_01244	3.68e-176	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAPKKHNH_01245	3.05e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MAPKKHNH_01246	1.31e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MAPKKHNH_01247	1.63e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MAPKKHNH_01248	8.44e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MAPKKHNH_01249	4.36e-93	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MAPKKHNH_01250	2.43e-95	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MAPKKHNH_01251	2.33e-130	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
MAPKKHNH_01252	3.87e-15	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
MAPKKHNH_01253	1.63e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MAPKKHNH_01254	1.73e-227	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MAPKKHNH_01256	1.21e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MAPKKHNH_01257	1.94e-130	-	-	-	I	-	-	-	PAP2 superfamily
MAPKKHNH_01258	1.23e-187	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MAPKKHNH_01259	1.43e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MAPKKHNH_01260	3.73e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MAPKKHNH_01261	3.87e-16	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MAPKKHNH_01262	2.08e-95	yfhC	-	-	C	-	-	-	nitroreductase
MAPKKHNH_01263	8.72e-258	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MAPKKHNH_01264	1.31e-56	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MAPKKHNH_01265	4.06e-39	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_01266	4.22e-288	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_01267	2.3e-169	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MAPKKHNH_01268	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MAPKKHNH_01269	2.73e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
MAPKKHNH_01270	1.64e-215	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_01271	7.88e-79	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
MAPKKHNH_01272	2.19e-73	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MAPKKHNH_01273	4.65e-166	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
MAPKKHNH_01274	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MAPKKHNH_01275	2.06e-111	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
MAPKKHNH_01276	3.14e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
MAPKKHNH_01277	4.49e-108	-	-	-	-	-	-	-	-
MAPKKHNH_01278	1.83e-54	-	-	-	C	-	-	-	FMN_bind
MAPKKHNH_01279	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MAPKKHNH_01280	4.2e-249	pbpX1	-	-	V	-	-	-	Beta-lactamase
MAPKKHNH_01281	2.48e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MAPKKHNH_01282	9.03e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAPKKHNH_01283	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MAPKKHNH_01284	3.66e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAPKKHNH_01285	3.29e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MAPKKHNH_01286	8.62e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MAPKKHNH_01287	1.39e-312	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MAPKKHNH_01288	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MAPKKHNH_01289	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MAPKKHNH_01290	1.27e-220	potE	-	-	E	-	-	-	Amino Acid
MAPKKHNH_01291	2.58e-48	potE	-	-	E	-	-	-	Amino Acid
MAPKKHNH_01292	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MAPKKHNH_01293	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MAPKKHNH_01294	2.56e-291	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MAPKKHNH_01295	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MAPKKHNH_01296	5.43e-191	-	-	-	-	-	-	-	-
MAPKKHNH_01297	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAPKKHNH_01298	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MAPKKHNH_01299	3.64e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MAPKKHNH_01300	2.57e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MAPKKHNH_01301	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MAPKKHNH_01302	2.7e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MAPKKHNH_01303	1.42e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MAPKKHNH_01304	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAPKKHNH_01305	5.21e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MAPKKHNH_01306	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MAPKKHNH_01307	3.91e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MAPKKHNH_01308	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MAPKKHNH_01309	2.79e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MAPKKHNH_01310	5.22e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MAPKKHNH_01311	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAPKKHNH_01312	1.79e-74	-	-	-	L	-	-	-	Resolvase, N-terminal
MAPKKHNH_01313	1.03e-208	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MAPKKHNH_01314	1.75e-211	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MAPKKHNH_01315	0.0	-	-	-	L	-	-	-	Nuclease-related domain
MAPKKHNH_01316	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MAPKKHNH_01317	2.31e-148	-	-	-	S	-	-	-	repeat protein
MAPKKHNH_01318	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MAPKKHNH_01319	4.47e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MAPKKHNH_01320	9.98e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MAPKKHNH_01321	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MAPKKHNH_01322	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MAPKKHNH_01323	1.22e-55	-	-	-	-	-	-	-	-
MAPKKHNH_01324	5.18e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MAPKKHNH_01325	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MAPKKHNH_01326	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAPKKHNH_01327	6.3e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MAPKKHNH_01328	4.01e-192	ylmH	-	-	S	-	-	-	S4 domain protein
MAPKKHNH_01329	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MAPKKHNH_01330	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MAPKKHNH_01331	2.52e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MAPKKHNH_01332	3.3e-315	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MAPKKHNH_01333	3.14e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MAPKKHNH_01334	3.88e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAPKKHNH_01335	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAPKKHNH_01336	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAPKKHNH_01337	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MAPKKHNH_01338	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MAPKKHNH_01339	1.49e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MAPKKHNH_01340	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MAPKKHNH_01341	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
MAPKKHNH_01342	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MAPKKHNH_01343	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
MAPKKHNH_01344	8.27e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MAPKKHNH_01345	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MAPKKHNH_01346	6.18e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MAPKKHNH_01347	1.06e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MAPKKHNH_01348	1.22e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MAPKKHNH_01349	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MAPKKHNH_01350	2.91e-67	-	-	-	-	-	-	-	-
MAPKKHNH_01351	3.02e-166	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MAPKKHNH_01352	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MAPKKHNH_01353	9.25e-13	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MAPKKHNH_01354	8.53e-59	-	-	-	-	-	-	-	-
MAPKKHNH_01355	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
MAPKKHNH_01356	4.08e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MAPKKHNH_01357	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
MAPKKHNH_01358	3.97e-57	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MAPKKHNH_01359	6.01e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MAPKKHNH_01360	2.1e-232	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MAPKKHNH_01361	3.48e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAPKKHNH_01362	1.67e-270	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MAPKKHNH_01363	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MAPKKHNH_01364	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MAPKKHNH_01365	8.08e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MAPKKHNH_01366	5.98e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MAPKKHNH_01367	1.35e-56	-	-	-	-	-	-	-	-
MAPKKHNH_01368	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
MAPKKHNH_01369	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MAPKKHNH_01370	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MAPKKHNH_01371	1.59e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MAPKKHNH_01372	4.81e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MAPKKHNH_01373	2.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MAPKKHNH_01374	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MAPKKHNH_01375	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MAPKKHNH_01376	1.04e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MAPKKHNH_01377	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MAPKKHNH_01378	3.24e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAPKKHNH_01379	2.57e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MAPKKHNH_01380	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAPKKHNH_01381	8.33e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MAPKKHNH_01382	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MAPKKHNH_01383	1.36e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MAPKKHNH_01384	1.24e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MAPKKHNH_01385	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAPKKHNH_01386	9.98e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MAPKKHNH_01387	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MAPKKHNH_01390	3.94e-250	ampC	-	-	V	-	-	-	Beta-lactamase
MAPKKHNH_01391	4.63e-274	-	-	-	EGP	-	-	-	Major Facilitator
MAPKKHNH_01392	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MAPKKHNH_01393	1.52e-136	vanZ	-	-	V	-	-	-	VanZ like family
MAPKKHNH_01394	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MAPKKHNH_01395	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MAPKKHNH_01396	1.97e-170	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MAPKKHNH_01397	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
MAPKKHNH_01398	1.93e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MAPKKHNH_01399	1.72e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MAPKKHNH_01400	2.45e-127	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MAPKKHNH_01401	2.9e-124	-	-	-	M	-	-	-	hydrolase, family 25
MAPKKHNH_01402	4.98e-21	-	-	-	-	-	-	-	-
MAPKKHNH_01412	1.45e-294	-	-	-	S	-	-	-	Phage minor structural protein
MAPKKHNH_01414	3.25e-193	-	-	-	D	-	-	-	domain protein
MAPKKHNH_01422	2.13e-181	-	-	-	S	-	-	-	peptidase activity
MAPKKHNH_01423	7.16e-84	-	-	-	S	-	-	-	Clp protease
MAPKKHNH_01424	5.55e-170	-	-	-	S	-	-	-	Phage portal protein
MAPKKHNH_01426	0.0	-	-	-	S	-	-	-	Phage Terminase
MAPKKHNH_01429	4.61e-75	-	-	-	S	-	-	-	Phage terminase, small subunit
MAPKKHNH_01431	4.2e-181	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAPKKHNH_01432	3.68e-14	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MAPKKHNH_01433	6.88e-11	-	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
MAPKKHNH_01435	1.94e-22	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
MAPKKHNH_01436	4.83e-125	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	VirC1 protein
MAPKKHNH_01438	3.03e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MAPKKHNH_01439	6.8e-48	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MAPKKHNH_01440	1.48e-95	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MAPKKHNH_01441	3.84e-299	-	-	-	V	-	-	-	N-6 DNA Methylase
MAPKKHNH_01443	3.64e-86	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MAPKKHNH_01444	2.38e-46	-	-	-	-	-	-	-	-
MAPKKHNH_01445	2.74e-28	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAPKKHNH_01446	4.38e-157	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MAPKKHNH_01448	7.33e-19	-	-	-	-	-	-	-	-
MAPKKHNH_01449	1.02e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
MAPKKHNH_01450	3.77e-54	-	-	-	E	-	-	-	Pfam:DUF955
MAPKKHNH_01451	3.71e-142	-	-	-	S	-	-	-	Fic/DOC family
MAPKKHNH_01452	4.2e-22	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MAPKKHNH_01453	1.74e-32	-	-	-	L	-	-	-	four-way junction helicase activity
MAPKKHNH_01462	8.52e-25	lysM	-	-	M	-	-	-	LysM domain
MAPKKHNH_01463	6.51e-194	-	-	-	S	-	-	-	COG0433 Predicted ATPase
MAPKKHNH_01467	5.28e-165	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MAPKKHNH_01472	2.74e-13	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_01473	4.5e-24	-	-	-	M	-	-	-	oxidoreductase activity
MAPKKHNH_01475	3.56e-21	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MAPKKHNH_01476	6.04e-05	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_01483	4.48e-10	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAPKKHNH_01485	9.34e-231	-	-	-	L	-	-	-	N-6 DNA Methylase
MAPKKHNH_01486	1.49e-47	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_01487	6.57e-45	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
MAPKKHNH_01494	2.72e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
MAPKKHNH_01497	2.13e-14	-	-	-	S	-	-	-	Arc-like DNA binding domain
MAPKKHNH_01499	2.62e-33	-	-	-	K	-	-	-	Helix-turn-helix domain
MAPKKHNH_01500	1.09e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_01501	1.11e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MAPKKHNH_01503	2.76e-189	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAPKKHNH_01505	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAPKKHNH_01506	2.42e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MAPKKHNH_01507	3.69e-30	-	-	-	-	-	-	-	-
MAPKKHNH_01508	1.94e-100	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MAPKKHNH_01509	1.68e-55	-	-	-	-	-	-	-	-
MAPKKHNH_01510	8.19e-91	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MAPKKHNH_01511	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MAPKKHNH_01512	1.72e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MAPKKHNH_01513	5.04e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MAPKKHNH_01514	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MAPKKHNH_01515	2.33e-120	-	-	-	S	-	-	-	VanZ like family
MAPKKHNH_01516	1.49e-130	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
MAPKKHNH_01517	3.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAPKKHNH_01519	4.31e-204	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MAPKKHNH_01520	2.15e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
MAPKKHNH_01521	0.0	-	-	-	E	-	-	-	Amino acid permease
MAPKKHNH_01523	1.14e-99	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAPKKHNH_01524	1.96e-110	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
MAPKKHNH_01525	2.64e-46	-	-	-	-	-	-	-	-
MAPKKHNH_01526	1.67e-136	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
MAPKKHNH_01527	2.21e-34	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
MAPKKHNH_01528	6.91e-118	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
MAPKKHNH_01529	5.12e-199	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MAPKKHNH_01530	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MAPKKHNH_01531	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MAPKKHNH_01532	8.39e-195	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MAPKKHNH_01533	2.52e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MAPKKHNH_01534	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MAPKKHNH_01535	2.85e-153	-	-	-	-	-	-	-	-
MAPKKHNH_01536	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MAPKKHNH_01537	8.04e-190	-	-	-	S	-	-	-	hydrolase
MAPKKHNH_01538	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAPKKHNH_01539	2.76e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
MAPKKHNH_01540	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MAPKKHNH_01541	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAPKKHNH_01542	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAPKKHNH_01543	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAPKKHNH_01544	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MAPKKHNH_01545	2.84e-208	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MAPKKHNH_01546	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MAPKKHNH_01547	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MAPKKHNH_01548	1.1e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MAPKKHNH_01549	1.64e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAPKKHNH_01550	4.66e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MAPKKHNH_01551	3.07e-124	-	-	-	-	-	-	-	-
MAPKKHNH_01552	5.85e-136	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MAPKKHNH_01553	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAPKKHNH_01554	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MAPKKHNH_01555	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MAPKKHNH_01556	9.53e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MAPKKHNH_01558	0.0	-	-	-	-	-	-	-	-
MAPKKHNH_01559	0.0	ycaM	-	-	E	-	-	-	amino acid
MAPKKHNH_01560	1.43e-178	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MAPKKHNH_01561	7.65e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MAPKKHNH_01562	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAPKKHNH_01563	4.64e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MAPKKHNH_01564	4.76e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MAPKKHNH_01565	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_01566	0.0	-	-	-	S	-	-	-	SH3-like domain
MAPKKHNH_01567	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MAPKKHNH_01568	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MAPKKHNH_01569	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MAPKKHNH_01570	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MAPKKHNH_01571	1.55e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MAPKKHNH_01572	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MAPKKHNH_01573	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MAPKKHNH_01574	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MAPKKHNH_01575	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MAPKKHNH_01576	3.31e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MAPKKHNH_01577	4.04e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAPKKHNH_01578	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MAPKKHNH_01579	8.33e-27	-	-	-	-	-	-	-	-
MAPKKHNH_01580	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MAPKKHNH_01581	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAPKKHNH_01582	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MAPKKHNH_01583	9.44e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MAPKKHNH_01584	1.55e-313	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MAPKKHNH_01585	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MAPKKHNH_01586	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MAPKKHNH_01587	3.03e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MAPKKHNH_01588	1.17e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAPKKHNH_01589	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MAPKKHNH_01590	1.63e-154	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MAPKKHNH_01591	1.39e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MAPKKHNH_01592	5.49e-301	ymfH	-	-	S	-	-	-	Peptidase M16
MAPKKHNH_01593	1.47e-284	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MAPKKHNH_01594	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MAPKKHNH_01595	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
MAPKKHNH_01596	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MAPKKHNH_01597	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
MAPKKHNH_01598	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MAPKKHNH_01599	1.01e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MAPKKHNH_01600	3.77e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
MAPKKHNH_01601	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MAPKKHNH_01602	7.96e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAPKKHNH_01603	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAPKKHNH_01604	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MAPKKHNH_01605	2.44e-143	-	-	-	S	-	-	-	CYTH
MAPKKHNH_01606	5.74e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
MAPKKHNH_01607	2.63e-205	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MAPKKHNH_01608	1.5e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MAPKKHNH_01609	6.28e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MAPKKHNH_01610	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MAPKKHNH_01611	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MAPKKHNH_01612	2.6e-37	-	-	-	-	-	-	-	-
MAPKKHNH_01613	1.28e-168	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MAPKKHNH_01614	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MAPKKHNH_01615	5.93e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MAPKKHNH_01616	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MAPKKHNH_01617	1.76e-181	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MAPKKHNH_01618	7.76e-98	-	-	-	-	-	-	-	-
MAPKKHNH_01619	1.74e-111	-	-	-	-	-	-	-	-
MAPKKHNH_01620	2.79e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MAPKKHNH_01621	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAPKKHNH_01622	1.94e-150	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MAPKKHNH_01623	1.04e-48	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MAPKKHNH_01624	7.74e-61	-	-	-	-	-	-	-	-
MAPKKHNH_01625	4.42e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MAPKKHNH_01626	1.22e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MAPKKHNH_01627	3.22e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MAPKKHNH_01628	3.44e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MAPKKHNH_01629	9.98e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MAPKKHNH_01630	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MAPKKHNH_01631	7.46e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
MAPKKHNH_01632	1.62e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MAPKKHNH_01634	1.15e-314	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_01635	5.96e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MAPKKHNH_01636	2.16e-79	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MAPKKHNH_01637	6.73e-78	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MAPKKHNH_01638	2.22e-296	-	-	-	E	ko:K03294	-	ko00000	amino acid
MAPKKHNH_01639	7.32e-157	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAPKKHNH_01640	6.74e-269	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAPKKHNH_01641	5.83e-67	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MAPKKHNH_01642	1.73e-114	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MAPKKHNH_01643	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAPKKHNH_01644	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAPKKHNH_01645	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MAPKKHNH_01646	2.14e-154	-	-	-	C	-	-	-	nitroreductase
MAPKKHNH_01647	1.76e-52	-	-	-	-	-	-	-	-
MAPKKHNH_01648	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MAPKKHNH_01649	1.52e-103	-	-	-	-	-	-	-	-
MAPKKHNH_01650	1.39e-189	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MAPKKHNH_01651	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MAPKKHNH_01652	7.44e-189	-	-	-	S	-	-	-	hydrolase
MAPKKHNH_01653	1.85e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
MAPKKHNH_01654	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MAPKKHNH_01655	4.44e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MAPKKHNH_01656	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
MAPKKHNH_01657	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MAPKKHNH_01658	6.63e-174	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MAPKKHNH_01659	1.01e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MAPKKHNH_01660	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MAPKKHNH_01661	1.82e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MAPKKHNH_01662	8.52e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAPKKHNH_01663	7.29e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MAPKKHNH_01664	2.2e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MAPKKHNH_01665	3.52e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MAPKKHNH_01666	2.09e-110	-	-	-	-	-	-	-	-
MAPKKHNH_01667	1.04e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MAPKKHNH_01668	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAPKKHNH_01669	4.29e-122	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAPKKHNH_01670	3.39e-187	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_01671	2.8e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_01672	2.72e-60	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
MAPKKHNH_01673	5.43e-50	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
MAPKKHNH_01674	2.68e-268	-	-	-	G	-	-	-	MFS/sugar transport protein
MAPKKHNH_01675	1.72e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MAPKKHNH_01676	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MAPKKHNH_01677	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_01678	2.53e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MAPKKHNH_01679	1.38e-186	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAPKKHNH_01680	1.07e-165	-	-	-	F	-	-	-	glutamine amidotransferase
MAPKKHNH_01681	3.41e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MAPKKHNH_01682	3.97e-33	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MAPKKHNH_01683	4.99e-74	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MAPKKHNH_01684	1.31e-145	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MAPKKHNH_01685	1.53e-176	-	-	-	-	-	-	-	-
MAPKKHNH_01686	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
MAPKKHNH_01687	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MAPKKHNH_01688	2.33e-230	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
MAPKKHNH_01689	1.06e-195	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MAPKKHNH_01690	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MAPKKHNH_01691	1.02e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MAPKKHNH_01692	3.34e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MAPKKHNH_01693	3.55e-28	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
MAPKKHNH_01694	8.97e-47	-	-	-	-	-	-	-	-
MAPKKHNH_01695	5.94e-200	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MAPKKHNH_01696	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAPKKHNH_01697	6.61e-186	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MAPKKHNH_01698	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MAPKKHNH_01699	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAPKKHNH_01700	1.27e-299	qacA	-	-	EGP	-	-	-	Major Facilitator
MAPKKHNH_01705	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAPKKHNH_01706	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAPKKHNH_01707	1.01e-256	flp	-	-	V	-	-	-	Beta-lactamase
MAPKKHNH_01708	2.79e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MAPKKHNH_01709	9.92e-187	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MAPKKHNH_01710	1.46e-75	-	-	-	-	-	-	-	-
MAPKKHNH_01711	2.61e-148	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MAPKKHNH_01712	5.58e-219	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MAPKKHNH_01713	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAPKKHNH_01714	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MAPKKHNH_01715	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAPKKHNH_01716	6.25e-268	camS	-	-	S	-	-	-	sex pheromone
MAPKKHNH_01717	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAPKKHNH_01718	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MAPKKHNH_01719	2.26e-118	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MAPKKHNH_01721	2.62e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MAPKKHNH_01722	5.48e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MAPKKHNH_01723	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MAPKKHNH_01724	9.16e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MAPKKHNH_01725	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MAPKKHNH_01726	9.83e-261	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MAPKKHNH_01727	1.29e-193	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MAPKKHNH_01728	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MAPKKHNH_01729	1.03e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
MAPKKHNH_01730	3.02e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MAPKKHNH_01731	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
MAPKKHNH_01732	1.87e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MAPKKHNH_01733	4.18e-230	-	-	-	-	-	-	-	-
MAPKKHNH_01734	1.15e-54	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAPKKHNH_01735	7.83e-303	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAPKKHNH_01738	7.62e-306	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
MAPKKHNH_01739	1.18e-13	-	-	-	-	-	-	-	-
MAPKKHNH_01740	6.39e-32	-	-	-	S	-	-	-	transposase or invertase
MAPKKHNH_01741	9.6e-309	slpX	-	-	S	-	-	-	SLAP domain
MAPKKHNH_01742	2.03e-186	-	-	-	K	-	-	-	SIS domain
MAPKKHNH_01743	1.05e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MAPKKHNH_01744	3.16e-232	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MAPKKHNH_01745	1.93e-266	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAPKKHNH_01747	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MAPKKHNH_01749	2.67e-148	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MAPKKHNH_01750	1.9e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MAPKKHNH_01751	9.01e-115	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
MAPKKHNH_01752	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MAPKKHNH_01753	5.68e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
MAPKKHNH_01754	1.33e-130	-	-	-	M	-	-	-	LysM domain protein
MAPKKHNH_01755	2.57e-108	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_01756	6.31e-99	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_01757	1.83e-22	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_01758	1.25e-17	-	-	-	-	-	-	-	-
MAPKKHNH_01759	2.77e-220	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MAPKKHNH_01760	1.04e-41	-	-	-	-	-	-	-	-
MAPKKHNH_01762	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MAPKKHNH_01763	1.08e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MAPKKHNH_01764	4.51e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MAPKKHNH_01766	2.44e-169	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MAPKKHNH_01767	1.49e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MAPKKHNH_01768	7.82e-80	-	-	-	-	-	-	-	-
MAPKKHNH_01769	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MAPKKHNH_01770	2.14e-312	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
MAPKKHNH_01771	5.53e-173	-	-	-	S	-	-	-	TerB-C domain
MAPKKHNH_01772	1.23e-242	-	-	-	S	-	-	-	TerB-C domain
MAPKKHNH_01773	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MAPKKHNH_01774	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MAPKKHNH_01775	6.94e-202	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_01776	9.05e-78	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
MAPKKHNH_01777	3.36e-42	-	-	-	-	-	-	-	-
MAPKKHNH_01778	1.78e-100	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MAPKKHNH_01779	5.26e-36	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MAPKKHNH_01780	2.7e-277	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
MAPKKHNH_01781	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_01782	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MAPKKHNH_01783	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
MAPKKHNH_01784	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MAPKKHNH_01785	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MAPKKHNH_01786	4.47e-58	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MAPKKHNH_01787	1.38e-309	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MAPKKHNH_01788	7.06e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MAPKKHNH_01789	2.07e-203	-	-	-	K	-	-	-	Transcriptional regulator
MAPKKHNH_01790	1.31e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MAPKKHNH_01791	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MAPKKHNH_01792	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MAPKKHNH_01793	2.72e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MAPKKHNH_01795	1.38e-165	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAPKKHNH_01796	9.06e-184	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAPKKHNH_01797	1.44e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAPKKHNH_01798	4.98e-37	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAPKKHNH_01799	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MAPKKHNH_01800	1.23e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MAPKKHNH_01801	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
MAPKKHNH_01802	1.77e-194	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAPKKHNH_01803	4.69e-201	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MAPKKHNH_01804	9.75e-20	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MAPKKHNH_01805	1.41e-37	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MAPKKHNH_01806	2.35e-117	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MAPKKHNH_01807	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MAPKKHNH_01808	1.2e-220	-	-	-	-	-	-	-	-
MAPKKHNH_01809	1.86e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAPKKHNH_01811	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
MAPKKHNH_01812	1.53e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAPKKHNH_01813	1.89e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MAPKKHNH_01814	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MAPKKHNH_01815	2.12e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MAPKKHNH_01816	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
MAPKKHNH_01817	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAPKKHNH_01818	1.64e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
MAPKKHNH_01819	5.26e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MAPKKHNH_01820	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAPKKHNH_01821	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MAPKKHNH_01822	1.29e-230	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MAPKKHNH_01823	5.11e-203	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MAPKKHNH_01824	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MAPKKHNH_01825	2.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MAPKKHNH_01826	7.8e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MAPKKHNH_01827	3.85e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MAPKKHNH_01828	6.31e-84	-	-	-	-	-	-	-	-
MAPKKHNH_01829	2.62e-69	-	-	-	-	-	-	-	-
MAPKKHNH_01831	4.4e-165	-	-	-	S	-	-	-	PAS domain
MAPKKHNH_01832	7.28e-209	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_01833	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MAPKKHNH_01834	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MAPKKHNH_01835	1.75e-168	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MAPKKHNH_01836	2.37e-242	-	-	-	T	-	-	-	GHKL domain
MAPKKHNH_01837	2.88e-98	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MAPKKHNH_01838	5.59e-109	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MAPKKHNH_01839	8e-108	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MAPKKHNH_01840	8.64e-85	yybA	-	-	K	-	-	-	Transcriptional regulator
MAPKKHNH_01841	2.91e-83	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MAPKKHNH_01842	1.13e-201	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MAPKKHNH_01843	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAPKKHNH_01844	1.04e-80	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MAPKKHNH_01845	1.45e-36	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MAPKKHNH_01846	2.15e-299	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MAPKKHNH_01847	1.24e-75	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MAPKKHNH_01848	1.48e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAPKKHNH_01849	1.95e-218	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MAPKKHNH_01850	1.88e-125	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MAPKKHNH_01851	1.36e-96	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MAPKKHNH_01852	7.09e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_01853	1.39e-135	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MAPKKHNH_01854	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAPKKHNH_01855	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MAPKKHNH_01856	1.47e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MAPKKHNH_01857	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
MAPKKHNH_01858	1.87e-308	-	-	-	S	-	-	-	response to antibiotic
MAPKKHNH_01859	1.34e-162	-	-	-	-	-	-	-	-
MAPKKHNH_01860	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MAPKKHNH_01861	6.28e-87	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MAPKKHNH_01862	1.42e-57	-	-	-	-	-	-	-	-
MAPKKHNH_01863	4.71e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MAPKKHNH_01864	1.43e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MAPKKHNH_01865	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
MAPKKHNH_01866	2.15e-197	-	-	-	-	-	-	-	-
MAPKKHNH_01867	3.32e-13	-	-	-	-	-	-	-	-
MAPKKHNH_01868	6.57e-113	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAPKKHNH_01869	1.18e-136	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MAPKKHNH_01872	3.67e-92	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MAPKKHNH_01873	1.36e-136	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MAPKKHNH_01874	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MAPKKHNH_01875	6.38e-95	-	-	-	L	-	-	-	Transposase DDE domain
MAPKKHNH_01877	1.42e-74	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MAPKKHNH_01878	3.39e-253	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MAPKKHNH_01879	1.49e-252	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MAPKKHNH_01881	1.74e-61	pglI	2.4.1.293	GT2	M	ko:K17250	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
MAPKKHNH_01883	8.76e-83	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MAPKKHNH_01884	3.46e-80	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
MAPKKHNH_01885	2.45e-97	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
MAPKKHNH_01886	1.17e-102	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
MAPKKHNH_01887	2.39e-222	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
MAPKKHNH_01888	1.43e-140	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MAPKKHNH_01889	3.16e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MAPKKHNH_01890	1.58e-154	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MAPKKHNH_01891	8.55e-191	epsB	-	-	M	-	-	-	biosynthesis protein
MAPKKHNH_01892	1.53e-245	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAPKKHNH_01893	2.09e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MAPKKHNH_01894	9.52e-56	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MAPKKHNH_01896	2.01e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAPKKHNH_01897	2.08e-222	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MAPKKHNH_01899	3.01e-54	-	-	-	-	-	-	-	-
MAPKKHNH_01900	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MAPKKHNH_01901	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MAPKKHNH_01902	1.47e-114	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MAPKKHNH_01903	4.26e-115	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
MAPKKHNH_01904	4.52e-56	-	-	-	-	-	-	-	-
MAPKKHNH_01905	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
MAPKKHNH_01906	8.77e-144	-	-	-	-	-	-	-	-
MAPKKHNH_01907	5.48e-283	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MAPKKHNH_01908	7.29e-62	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MAPKKHNH_01909	8.26e-216	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAPKKHNH_01910	1.16e-101	-	-	-	-	-	-	-	-
MAPKKHNH_01911	1.58e-143	-	-	-	S	-	-	-	Peptidase_C39 like family
MAPKKHNH_01912	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MAPKKHNH_01913	7.35e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
MAPKKHNH_01914	0.0	-	-	-	S	-	-	-	ABC transporter
MAPKKHNH_01915	2.52e-76	-	-	-	-	-	-	-	-
MAPKKHNH_01916	8.69e-93	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MAPKKHNH_01917	5.49e-46	-	-	-	-	-	-	-	-
MAPKKHNH_01918	7.2e-40	-	-	-	-	-	-	-	-
MAPKKHNH_01919	2.33e-143	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MAPKKHNH_01920	5.74e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAPKKHNH_01921	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MAPKKHNH_01922	7.27e-42	-	-	-	-	-	-	-	-
MAPKKHNH_01923	1.47e-91	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
MAPKKHNH_01926	4.61e-37	-	-	-	S	-	-	-	Enterocin A Immunity
MAPKKHNH_01929	1.13e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MAPKKHNH_01930	0.000868	-	-	-	-	-	-	-	-
MAPKKHNH_01931	1.18e-276	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MAPKKHNH_01932	6.6e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MAPKKHNH_01933	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MAPKKHNH_01934	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MAPKKHNH_01935	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MAPKKHNH_01936	9.9e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MAPKKHNH_01937	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MAPKKHNH_01938	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MAPKKHNH_01939	3.61e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MAPKKHNH_01940	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MAPKKHNH_01941	6.39e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MAPKKHNH_01942	3.09e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_01943	3.41e-88	-	-	-	-	-	-	-	-
MAPKKHNH_01944	2.52e-32	-	-	-	-	-	-	-	-
MAPKKHNH_01945	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MAPKKHNH_01946	4.74e-107	-	-	-	-	-	-	-	-
MAPKKHNH_01947	7.87e-30	-	-	-	-	-	-	-	-
MAPKKHNH_01951	5.02e-180	blpT	-	-	-	-	-	-	-
MAPKKHNH_01952	7.86e-138	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
MAPKKHNH_01953	1.85e-141	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAPKKHNH_01954	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAPKKHNH_01955	2.08e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MAPKKHNH_01956	8.83e-170	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MAPKKHNH_01957	1.89e-23	-	-	-	-	-	-	-	-
MAPKKHNH_01958	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MAPKKHNH_01959	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MAPKKHNH_01960	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MAPKKHNH_01961	4.48e-34	-	-	-	-	-	-	-	-
MAPKKHNH_01962	1.07e-35	-	-	-	-	-	-	-	-
MAPKKHNH_01963	1.95e-45	-	-	-	-	-	-	-	-
MAPKKHNH_01964	6.94e-70	-	-	-	S	-	-	-	Enterocin A Immunity
MAPKKHNH_01965	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MAPKKHNH_01966	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAPKKHNH_01967	9.28e-271	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MAPKKHNH_01968	8.32e-157	vanR	-	-	K	-	-	-	response regulator
MAPKKHNH_01970	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MAPKKHNH_01971	1.68e-179	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_01972	1.22e-190	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_01973	9.8e-58	-	-	-	L	-	-	-	Transposase
MAPKKHNH_01974	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MAPKKHNH_01975	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MAPKKHNH_01976	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MAPKKHNH_01977	1.49e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MAPKKHNH_01978	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MAPKKHNH_01979	1.18e-190	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MAPKKHNH_01980	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MAPKKHNH_01981	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
MAPKKHNH_01983	5.24e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MAPKKHNH_01984	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MAPKKHNH_01985	7.4e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MAPKKHNH_01986	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MAPKKHNH_01987	1.25e-143	-	-	-	K	-	-	-	WHG domain
MAPKKHNH_01988	2.63e-50	-	-	-	-	-	-	-	-
MAPKKHNH_01989	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAPKKHNH_01990	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_01991	1.05e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MAPKKHNH_01992	1.45e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAPKKHNH_01993	2.75e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
MAPKKHNH_01994	9.79e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
MAPKKHNH_01995	1.45e-183	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MAPKKHNH_01996	5.5e-155	-	-	-	-	-	-	-	-
MAPKKHNH_01997	9.18e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MAPKKHNH_01998	3.58e-251	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MAPKKHNH_01999	2.61e-23	-	-	-	-	-	-	-	-
MAPKKHNH_02000	3.15e-121	-	-	-	S	-	-	-	membrane
MAPKKHNH_02001	5.3e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
MAPKKHNH_02002	6.93e-34	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
MAPKKHNH_02003	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MAPKKHNH_02004	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MAPKKHNH_02005	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
MAPKKHNH_02006	7.62e-223	-	-	-	-	-	-	-	-
MAPKKHNH_02007	6.74e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MAPKKHNH_02008	1.27e-58	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MAPKKHNH_02009	1.86e-114	ymdB	-	-	S	-	-	-	Macro domain protein
MAPKKHNH_02014	4.73e-84	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_02015	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAPKKHNH_02016	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAPKKHNH_02017	2.73e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MAPKKHNH_02018	2.85e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MAPKKHNH_02019	7.7e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MAPKKHNH_02020	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MAPKKHNH_02021	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MAPKKHNH_02022	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MAPKKHNH_02023	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
MAPKKHNH_02024	6.36e-230	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MAPKKHNH_02025	4.24e-46	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MAPKKHNH_02026	4.23e-46	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_02027	1e-131	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MAPKKHNH_02028	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MAPKKHNH_02029	3.66e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MAPKKHNH_02030	1.74e-248	-	-	-	G	-	-	-	Transmembrane secretion effector
MAPKKHNH_02031	5.63e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
MAPKKHNH_02032	3.65e-285	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MAPKKHNH_02033	1.83e-91	-	-	-	V	-	-	-	ABC transporter transmembrane region
MAPKKHNH_02034	6.69e-84	-	-	-	L	-	-	-	RelB antitoxin
MAPKKHNH_02035	1.51e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MAPKKHNH_02036	8.6e-108	-	-	-	M	-	-	-	NlpC/P60 family
MAPKKHNH_02039	1.02e-200	-	-	-	-	-	-	-	-
MAPKKHNH_02040	1.03e-07	-	-	-	-	-	-	-	-
MAPKKHNH_02041	5.51e-47	-	-	-	-	-	-	-	-
MAPKKHNH_02042	4.48e-206	-	-	-	EG	-	-	-	EamA-like transporter family
MAPKKHNH_02043	3.18e-209	-	-	-	EG	-	-	-	EamA-like transporter family
MAPKKHNH_02044	3.75e-178	yicL	-	-	EG	-	-	-	EamA-like transporter family
MAPKKHNH_02045	1.32e-137	-	-	-	-	-	-	-	-
MAPKKHNH_02046	9.07e-143	-	-	-	-	-	-	-	-
MAPKKHNH_02047	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
MAPKKHNH_02048	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MAPKKHNH_02049	6.77e-111	-	-	-	-	-	-	-	-
MAPKKHNH_02050	1.09e-74	-	-	-	-	-	-	-	-
MAPKKHNH_02051	7.26e-35	-	-	-	S	-	-	-	Protein conserved in bacteria
MAPKKHNH_02052	2.27e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
MAPKKHNH_02053	1.01e-38	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MAPKKHNH_02054	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAPKKHNH_02055	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAPKKHNH_02056	1.35e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MAPKKHNH_02059	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MAPKKHNH_02060	5.12e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MAPKKHNH_02061	6.45e-291	-	-	-	E	-	-	-	amino acid
MAPKKHNH_02062	6.65e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MAPKKHNH_02064	1.95e-221	-	-	-	V	-	-	-	HNH endonuclease
MAPKKHNH_02065	5.05e-114	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MAPKKHNH_02066	3.44e-63	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MAPKKHNH_02067	5.27e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MAPKKHNH_02068	2.58e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MAPKKHNH_02069	5.08e-149	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MAPKKHNH_02070	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
MAPKKHNH_02071	7.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MAPKKHNH_02072	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPKKHNH_02073	1.68e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_02074	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MAPKKHNH_02075	1.96e-49	-	-	-	-	-	-	-	-
MAPKKHNH_02076	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MAPKKHNH_02077	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MAPKKHNH_02078	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MAPKKHNH_02079	1.97e-227	pbpX2	-	-	V	-	-	-	Beta-lactamase
MAPKKHNH_02080	1.82e-313	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MAPKKHNH_02081	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAPKKHNH_02082	2.95e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MAPKKHNH_02083	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAPKKHNH_02084	1.3e-26	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MAPKKHNH_02085	1.42e-58	-	-	-	-	-	-	-	-
MAPKKHNH_02086	5.11e-265	-	-	-	S	-	-	-	Membrane
MAPKKHNH_02087	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
MAPKKHNH_02088	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MAPKKHNH_02089	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MAPKKHNH_02090	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MAPKKHNH_02091	1.68e-55	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MAPKKHNH_02092	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MAPKKHNH_02093	1.91e-200	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_02094	1.05e-67	-	-	-	-	-	-	-	-
MAPKKHNH_02095	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MAPKKHNH_02096	1.49e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MAPKKHNH_02097	3.43e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAPKKHNH_02098	5.14e-248	-	-	-	S	-	-	-	DUF218 domain
MAPKKHNH_02099	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_02100	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MAPKKHNH_02101	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MAPKKHNH_02102	1.97e-255	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MAPKKHNH_02103	4.57e-232	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MAPKKHNH_02104	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MAPKKHNH_02105	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MAPKKHNH_02106	2.1e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MAPKKHNH_02107	3.08e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
MAPKKHNH_02108	1.15e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MAPKKHNH_02109	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MAPKKHNH_02110	1.06e-159	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MAPKKHNH_02111	6.64e-94	-	-	-	-	-	-	-	-
MAPKKHNH_02112	4.24e-178	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MAPKKHNH_02113	6.82e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MAPKKHNH_02114	1.91e-97	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MAPKKHNH_02115	4.03e-75	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MAPKKHNH_02116	2.53e-117	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAPKKHNH_02117	3.31e-154	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MAPKKHNH_02118	8.06e-110	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MAPKKHNH_02119	2.29e-162	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MAPKKHNH_02120	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
MAPKKHNH_02121	5.05e-11	-	-	-	-	-	-	-	-
MAPKKHNH_02122	3.58e-61	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MAPKKHNH_02124	4.06e-108	yneE	-	-	K	-	-	-	Transcriptional regulator
MAPKKHNH_02125	1.92e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
MAPKKHNH_02126	1.56e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MAPKKHNH_02127	5.26e-188	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MAPKKHNH_02128	4.45e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MAPKKHNH_02129	1.13e-44	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MAPKKHNH_02130	3.61e-212	-	-	-	V	-	-	-	ABC transporter transmembrane region
MAPKKHNH_02131	1.26e-176	-	-	-	-	-	-	-	-
MAPKKHNH_02135	3.15e-48	-	-	-	-	-	-	-	-
MAPKKHNH_02136	5.94e-75	-	-	-	S	-	-	-	Cupredoxin-like domain
MAPKKHNH_02137	3.27e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
MAPKKHNH_02138	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MAPKKHNH_02139	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MAPKKHNH_02140	3.14e-137	-	-	-	-	-	-	-	-
MAPKKHNH_02141	1.83e-316	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MAPKKHNH_02142	6.46e-27	-	-	-	-	-	-	-	-
MAPKKHNH_02143	3.91e-269	-	-	-	-	-	-	-	-
MAPKKHNH_02144	6.57e-175	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_02145	1.14e-154	-	-	-	S	-	-	-	SLAP domain
MAPKKHNH_02146	4.54e-135	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MAPKKHNH_02147	4.75e-58	-	-	-	-	-	-	-	-
MAPKKHNH_02148	2.38e-75	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_02149	1.21e-42	-	-	-	E	-	-	-	Zn peptidase
MAPKKHNH_02150	2.61e-90	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MAPKKHNH_02151	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAPKKHNH_02152	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MAPKKHNH_02153	2.42e-40	-	-	-	-	-	-	-	-
MAPKKHNH_02154	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MAPKKHNH_02155	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MAPKKHNH_02156	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MAPKKHNH_02157	3.37e-192	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAPKKHNH_02158	2.65e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MAPKKHNH_02159	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MAPKKHNH_02160	3.11e-256	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAPKKHNH_02161	4.84e-42	-	-	-	-	-	-	-	-
MAPKKHNH_02162	9.14e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MAPKKHNH_02163	8.73e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MAPKKHNH_02164	8.63e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MAPKKHNH_02165	4.66e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAPKKHNH_02166	6.07e-138	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MAPKKHNH_02167	2.69e-156	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MAPKKHNH_02168	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAPKKHNH_02169	6.1e-186	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_02170	2.55e-65	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_02172	4.97e-45	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537,ko:K12952	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
MAPKKHNH_02173	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
MAPKKHNH_02174	2.52e-06	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
MAPKKHNH_02175	6.33e-221	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
MAPKKHNH_02176	4.93e-80	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MAPKKHNH_02177	1.97e-294	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MAPKKHNH_02178	4.82e-42	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MAPKKHNH_02179	2.85e-115	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
MAPKKHNH_02180	1.78e-163	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
MAPKKHNH_02181	1.52e-157	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MAPKKHNH_02182	5.85e-86	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
MAPKKHNH_02183	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MAPKKHNH_02184	1.01e-22	-	-	-	L	-	-	-	Transposase
MAPKKHNH_02185	7.51e-16	-	-	-	L	-	-	-	Transposase
MAPKKHNH_02186	1.21e-72	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAPKKHNH_02187	8.71e-29	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MAPKKHNH_02189	1.06e-30	-	-	-	N	-	-	-	PFAM Uncharacterised protein family UPF0150
MAPKKHNH_02190	4.1e-96	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_02191	5.7e-69	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_02193	6.06e-58	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MAPKKHNH_02194	6.27e-161	-	-	-	L	-	-	-	Transposase
MAPKKHNH_02197	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
MAPKKHNH_02200	9.18e-187	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAPKKHNH_02202	9.54e-88	-	-	-	S	-	-	-	AAA domain
MAPKKHNH_02203	8.93e-33	-	-	-	S	-	-	-	HNH endonuclease
MAPKKHNH_02210	3.24e-94	-	-	-	S	-	-	-	Phage antirepressor protein KilAC domain
MAPKKHNH_02211	3.25e-23	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_02212	1.7e-23	-	-	-	-	-	-	-	-
MAPKKHNH_02215	2.79e-10	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_02217	2.99e-31	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
MAPKKHNH_02220	4.47e-20	-	-	-	L	-	-	-	Replication initiation factor
MAPKKHNH_02221	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAPKKHNH_02222	5.23e-97	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MAPKKHNH_02223	2.46e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAPKKHNH_02224	1.07e-141	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MAPKKHNH_02225	6.91e-92	-	-	-	L	-	-	-	IS1381, transposase OrfA
MAPKKHNH_02226	5.88e-212	repA	-	-	S	-	-	-	Replication initiator protein A
MAPKKHNH_02227	4.65e-184	-	-	-	D	-	-	-	AAA domain
MAPKKHNH_02228	1.17e-38	-	-	-	-	-	-	-	-
MAPKKHNH_02229	1.28e-33	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAPKKHNH_02231	3.65e-203	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAPKKHNH_02232	3.93e-118	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
MAPKKHNH_02233	2.59e-219	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MAPKKHNH_02234	5.21e-29	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MAPKKHNH_02235	1.14e-44	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MAPKKHNH_02236	1.75e-145	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
MAPKKHNH_02237	4.24e-78	farR	-	-	K	-	-	-	Helix-turn-helix domain
MAPKKHNH_02239	1.28e-33	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAPKKHNH_02240	1.27e-311	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MAPKKHNH_02241	1.64e-59	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MAPKKHNH_02242	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MAPKKHNH_02243	6.98e-78	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MAPKKHNH_02244	1.39e-224	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAPKKHNH_02245	6.22e-232	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MAPKKHNH_02246	4.43e-179	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MAPKKHNH_02247	3.98e-97	-	-	-	M	-	-	-	LysM domain
MAPKKHNH_02248	3.3e-42	-	-	-	-	-	-	-	-
MAPKKHNH_02250	6.29e-38	-	-	-	-	-	-	-	-
MAPKKHNH_02251	1.38e-95	-	-	-	EGP	-	-	-	Major Facilitator
MAPKKHNH_02252	9.16e-301	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MAPKKHNH_02253	1.48e-139	-	-	-	EGP	-	-	-	Major Facilitator
MAPKKHNH_02254	1.08e-161	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MAPKKHNH_02255	1.69e-59	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAPKKHNH_02256	1.64e-169	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAPKKHNH_02257	8.27e-88	-	-	-	GM	-	-	-	NAD(P)H-binding
MAPKKHNH_02258	1.59e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
MAPKKHNH_02259	3.49e-113	-	-	-	K	-	-	-	LysR substrate binding domain
MAPKKHNH_02261	4.52e-57	-	-	-	K	-	-	-	Tetracycline repressor, C-terminal all-alpha domain
MAPKKHNH_02262	5.94e-100	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
MAPKKHNH_02264	1.5e-27	-	-	-	S	-	-	-	Enterocin A Immunity
MAPKKHNH_02266	1.23e-54	-	-	-	V	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
MAPKKHNH_02267	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAPKKHNH_02268	1.64e-101	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MAPKKHNH_02269	1.79e-99	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MAPKKHNH_02270	1.5e-93	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MAPKKHNH_02271	2.47e-104	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MAPKKHNH_02272	1.44e-164	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAPKKHNH_02273	4.67e-54	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAPKKHNH_02274	9.07e-51	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MAPKKHNH_02275	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MAPKKHNH_02276	4.51e-130	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MAPKKHNH_02277	4.1e-34	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MAPKKHNH_02278	5.34e-77	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MAPKKHNH_02279	4.63e-32	-	-	-	-	-	-	-	-
MAPKKHNH_02280	6.72e-177	-	-	-	EP	-	-	-	Plasmid replication protein
MAPKKHNH_02281	8.08e-43	-	-	-	S	-	-	-	helix_turn_helix, Deoxyribose operon repressor
MAPKKHNH_02288	2.71e-49	-	-	-	S	-	-	-	VRR_NUC
MAPKKHNH_02289	6.04e-70	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MAPKKHNH_02290	2.22e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAPKKHNH_02291	1.45e-133	-	-	-	-	-	-	-	-
MAPKKHNH_02294	2.14e-103	-	-	-	-	-	-	-	-
MAPKKHNH_02295	9.13e-157	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MAPKKHNH_02296	1.29e-41	-	-	-	O	-	-	-	OsmC-like protein
MAPKKHNH_02298	1.33e-44	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MAPKKHNH_02299	0.0	-	-	-	L	-	-	-	Transposase DDE domain
MAPKKHNH_02300	6.59e-296	-	-	-	L	-	-	-	Transposase DDE domain
MAPKKHNH_02301	1.08e-229	-	-	-	L	-	-	-	DDE superfamily endonuclease
MAPKKHNH_02302	2.24e-71	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MAPKKHNH_02303	7.43e-42	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAPKKHNH_02305	8.39e-165	-	-	-	S	-	-	-	Fic/DOC family
MAPKKHNH_02308	5.22e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
MAPKKHNH_02309	5.45e-72	-	-	-	-	-	-	-	-
MAPKKHNH_02312	2.16e-75	-	-	-	V	-	-	-	Abi-like protein
MAPKKHNH_02313	2.41e-39	-	-	-	-	-	-	-	-
MAPKKHNH_02316	9.62e-25	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAPKKHNH_02317	7.88e-59	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
MAPKKHNH_02319	9.14e-203	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)