ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GKFLCFJD_00001 5.55e-301 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKFLCFJD_00002 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKFLCFJD_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
GKFLCFJD_00004 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKFLCFJD_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
GKFLCFJD_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKFLCFJD_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKFLCFJD_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00011 4.5e-234 yaaC - - S - - - YaaC-like Protein
GKFLCFJD_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GKFLCFJD_00013 2.81e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKFLCFJD_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GKFLCFJD_00015 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GKFLCFJD_00016 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKFLCFJD_00018 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
GKFLCFJD_00019 2.43e-150 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
GKFLCFJD_00020 7.7e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
GKFLCFJD_00021 1.44e-127 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
GKFLCFJD_00022 1.55e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKFLCFJD_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKFLCFJD_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKFLCFJD_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKFLCFJD_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
GKFLCFJD_00027 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
GKFLCFJD_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
GKFLCFJD_00032 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
GKFLCFJD_00033 5.05e-260 yaaN - - P - - - Belongs to the TelA family
GKFLCFJD_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
GKFLCFJD_00035 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKFLCFJD_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
GKFLCFJD_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
GKFLCFJD_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GKFLCFJD_00039 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
GKFLCFJD_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
GKFLCFJD_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
GKFLCFJD_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
GKFLCFJD_00043 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKFLCFJD_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
GKFLCFJD_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKFLCFJD_00046 5.05e-185 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
GKFLCFJD_00047 1.91e-283 yabE - - T - - - protein conserved in bacteria
GKFLCFJD_00048 1.05e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKFLCFJD_00049 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKFLCFJD_00050 6.69e-200 yabG - - S ko:K06436 - ko00000 peptidase
GKFLCFJD_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
GKFLCFJD_00052 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
GKFLCFJD_00053 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GKFLCFJD_00054 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GKFLCFJD_00055 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
GKFLCFJD_00056 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
GKFLCFJD_00057 9e-310 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKFLCFJD_00058 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKFLCFJD_00059 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GKFLCFJD_00060 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKFLCFJD_00061 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
GKFLCFJD_00062 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKFLCFJD_00063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
GKFLCFJD_00064 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKFLCFJD_00065 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
GKFLCFJD_00066 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GKFLCFJD_00067 1.91e-66 yabP - - S - - - Sporulation protein YabP
GKFLCFJD_00068 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
GKFLCFJD_00069 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GKFLCFJD_00070 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
GKFLCFJD_00073 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
GKFLCFJD_00074 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GKFLCFJD_00075 1.25e-238 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
GKFLCFJD_00076 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKFLCFJD_00077 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
GKFLCFJD_00078 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKFLCFJD_00079 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GKFLCFJD_00080 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKFLCFJD_00081 6.68e-196 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
GKFLCFJD_00082 3.77e-218 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GKFLCFJD_00083 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GKFLCFJD_00084 1.03e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
GKFLCFJD_00085 2.27e-216 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
GKFLCFJD_00086 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GKFLCFJD_00087 2.78e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKFLCFJD_00088 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GKFLCFJD_00089 1.81e-41 yazB - - K - - - transcriptional
GKFLCFJD_00090 7.88e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKFLCFJD_00091 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GKFLCFJD_00092 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00102 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00103 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GKFLCFJD_00104 2.76e-65 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
GKFLCFJD_00105 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
GKFLCFJD_00106 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
GKFLCFJD_00107 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKFLCFJD_00108 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GKFLCFJD_00109 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
GKFLCFJD_00110 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GKFLCFJD_00111 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GKFLCFJD_00112 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKFLCFJD_00113 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
GKFLCFJD_00114 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GKFLCFJD_00115 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKFLCFJD_00116 4.29e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKFLCFJD_00117 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
GKFLCFJD_00118 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
GKFLCFJD_00119 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GKFLCFJD_00120 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GKFLCFJD_00121 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKFLCFJD_00122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKFLCFJD_00123 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKFLCFJD_00124 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKFLCFJD_00125 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
GKFLCFJD_00126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKFLCFJD_00127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKFLCFJD_00128 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
GKFLCFJD_00129 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKFLCFJD_00130 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKFLCFJD_00131 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKFLCFJD_00132 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKFLCFJD_00133 8.78e-238 ybaC - - S - - - Alpha/beta hydrolase family
GKFLCFJD_00134 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GKFLCFJD_00135 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKFLCFJD_00136 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GKFLCFJD_00137 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKFLCFJD_00138 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKFLCFJD_00139 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKFLCFJD_00140 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKFLCFJD_00141 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKFLCFJD_00142 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKFLCFJD_00143 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GKFLCFJD_00144 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKFLCFJD_00145 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKFLCFJD_00146 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKFLCFJD_00147 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKFLCFJD_00148 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKFLCFJD_00149 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKFLCFJD_00150 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKFLCFJD_00151 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKFLCFJD_00152 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKFLCFJD_00153 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GKFLCFJD_00154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GKFLCFJD_00155 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKFLCFJD_00156 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKFLCFJD_00157 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
GKFLCFJD_00158 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKFLCFJD_00159 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GKFLCFJD_00160 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKFLCFJD_00161 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKFLCFJD_00162 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKFLCFJD_00163 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GKFLCFJD_00164 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKFLCFJD_00165 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKFLCFJD_00166 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKFLCFJD_00167 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKFLCFJD_00168 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKFLCFJD_00169 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GKFLCFJD_00170 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
GKFLCFJD_00171 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
GKFLCFJD_00172 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GKFLCFJD_00173 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GKFLCFJD_00174 1.04e-122 gerD - - - ko:K06294 - ko00000 -
GKFLCFJD_00175 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
GKFLCFJD_00176 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
GKFLCFJD_00177 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00184 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00186 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
GKFLCFJD_00188 3.47e-205 ybaS - - S - - - Na -dependent transporter
GKFLCFJD_00189 4.01e-184 ybbA - - S ko:K07017 - ko00000 Putative esterase
GKFLCFJD_00190 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_00191 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_00192 9.23e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
GKFLCFJD_00193 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
GKFLCFJD_00194 3.6e-306 ybbC - - S - - - protein conserved in bacteria
GKFLCFJD_00195 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
GKFLCFJD_00196 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
GKFLCFJD_00197 7.29e-304 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_00198 3.82e-194 ybbH - - K - - - transcriptional
GKFLCFJD_00199 4.04e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKFLCFJD_00200 1.55e-114 ybbJ - - J - - - acetyltransferase
GKFLCFJD_00201 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
GKFLCFJD_00207 1.6e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_00208 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
GKFLCFJD_00209 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKFLCFJD_00210 4.16e-292 ybbR - - S - - - protein conserved in bacteria
GKFLCFJD_00211 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKFLCFJD_00212 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKFLCFJD_00213 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GKFLCFJD_00214 2.25e-157 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
GKFLCFJD_00215 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKFLCFJD_00216 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GKFLCFJD_00217 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
GKFLCFJD_00218 2.51e-125 ybcF - - P - - - carbonic anhydrase
GKFLCFJD_00219 5.59e-64 - - - - - - - -
GKFLCFJD_00220 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
GKFLCFJD_00221 9.45e-67 - - - K - - - Helix-turn-helix domain
GKFLCFJD_00222 1.14e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
GKFLCFJD_00224 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
GKFLCFJD_00225 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
GKFLCFJD_00226 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKFLCFJD_00227 3.99e-313 skfF - - S - - - ABC transporter
GKFLCFJD_00228 3.88e-118 - - - C - - - HEAT repeats
GKFLCFJD_00229 5.88e-103 - - - CO - - - Thioredoxin-like domain
GKFLCFJD_00230 8.07e-233 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GKFLCFJD_00231 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
GKFLCFJD_00232 4.12e-221 - - - T - - - His Kinase A (phospho-acceptor) domain
GKFLCFJD_00234 2.49e-181 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
GKFLCFJD_00235 6.61e-196 ybdN - - - - - - -
GKFLCFJD_00236 1.19e-278 ybdO - - S - - - Domain of unknown function (DUF4885)
GKFLCFJD_00237 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GKFLCFJD_00238 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
GKFLCFJD_00239 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
GKFLCFJD_00240 3.86e-195 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
GKFLCFJD_00241 9.97e-317 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
GKFLCFJD_00242 1.11e-54 ybyB - - - - - - -
GKFLCFJD_00243 0.0 ybeC - - E - - - amino acid
GKFLCFJD_00244 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
GKFLCFJD_00245 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
GKFLCFJD_00246 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
GKFLCFJD_00247 8.93e-220 ybfA - - K - - - FR47-like protein
GKFLCFJD_00248 2.36e-287 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_00250 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
GKFLCFJD_00251 5.27e-208 ybfH - - EG - - - EamA-like transporter family
GKFLCFJD_00252 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
GKFLCFJD_00253 5.85e-274 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GKFLCFJD_00254 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
GKFLCFJD_00256 2.02e-216 - - - S - - - Alpha/beta hydrolase family
GKFLCFJD_00257 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKFLCFJD_00258 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
GKFLCFJD_00259 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
GKFLCFJD_00260 2.33e-61 ybfN - - - - - - -
GKFLCFJD_00261 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
GKFLCFJD_00262 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_00263 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
GKFLCFJD_00264 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKFLCFJD_00265 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_00266 7.72e-177 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKFLCFJD_00267 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
GKFLCFJD_00269 9.84e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
GKFLCFJD_00270 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKFLCFJD_00271 2.23e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
GKFLCFJD_00272 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
GKFLCFJD_00273 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GKFLCFJD_00274 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_00275 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
GKFLCFJD_00276 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
GKFLCFJD_00277 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKFLCFJD_00278 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_00279 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GKFLCFJD_00280 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
GKFLCFJD_00281 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
GKFLCFJD_00282 4.64e-227 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
GKFLCFJD_00283 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
GKFLCFJD_00284 1.87e-220 eamA1 - - EG - - - spore germination
GKFLCFJD_00285 6.64e-162 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_00286 1.66e-218 ycbM - - T - - - Histidine kinase
GKFLCFJD_00287 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_00288 4.25e-150 - - - S - - - ABC-2 family transporter protein
GKFLCFJD_00289 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
GKFLCFJD_00290 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
GKFLCFJD_00291 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
GKFLCFJD_00292 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
GKFLCFJD_00293 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GKFLCFJD_00294 7.6e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKFLCFJD_00295 2.52e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GKFLCFJD_00296 3.48e-268 ycbU - - E - - - Selenocysteine lyase
GKFLCFJD_00297 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
GKFLCFJD_00298 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
GKFLCFJD_00299 8.74e-260 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GKFLCFJD_00300 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
GKFLCFJD_00301 4.32e-78 - - - S - - - RDD family
GKFLCFJD_00302 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
GKFLCFJD_00303 9.56e-217 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKFLCFJD_00304 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKFLCFJD_00305 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
GKFLCFJD_00306 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GKFLCFJD_00307 5.83e-223 yccK - - C - - - Aldo keto reductase
GKFLCFJD_00308 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
GKFLCFJD_00309 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_00310 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_00311 3.91e-125 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
GKFLCFJD_00312 1.42e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
GKFLCFJD_00313 5.87e-181 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
GKFLCFJD_00314 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GKFLCFJD_00315 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKFLCFJD_00316 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GKFLCFJD_00317 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GKFLCFJD_00318 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKFLCFJD_00319 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
GKFLCFJD_00320 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
GKFLCFJD_00321 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
GKFLCFJD_00322 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
GKFLCFJD_00323 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
GKFLCFJD_00324 2.96e-245 yceH - - P - - - Belongs to the TelA family
GKFLCFJD_00325 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
GKFLCFJD_00326 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
GKFLCFJD_00327 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GKFLCFJD_00328 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
GKFLCFJD_00329 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
GKFLCFJD_00330 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
GKFLCFJD_00331 2.5e-279 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
GKFLCFJD_00332 0.0 ycgA - - S - - - Membrane
GKFLCFJD_00333 1.25e-127 ycgB - - - - - - -
GKFLCFJD_00334 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
GKFLCFJD_00335 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKFLCFJD_00336 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GKFLCFJD_00337 0.0 mdr - - EGP - - - the major facilitator superfamily
GKFLCFJD_00338 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_00339 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
GKFLCFJD_00340 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
GKFLCFJD_00341 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GKFLCFJD_00342 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
GKFLCFJD_00343 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKFLCFJD_00344 1.31e-140 tmrB - - S - - - AAA domain
GKFLCFJD_00345 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GKFLCFJD_00346 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
GKFLCFJD_00347 2.05e-230 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
GKFLCFJD_00348 1.15e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
GKFLCFJD_00349 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
GKFLCFJD_00350 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
GKFLCFJD_00351 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
GKFLCFJD_00352 4.65e-188 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKFLCFJD_00353 1.71e-96 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKFLCFJD_00354 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
GKFLCFJD_00355 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
GKFLCFJD_00356 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
GKFLCFJD_00357 4.74e-209 ycgS - - I - - - alpha/beta hydrolase fold
GKFLCFJD_00358 8.9e-247 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GKFLCFJD_00359 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
GKFLCFJD_00360 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
GKFLCFJD_00361 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GKFLCFJD_00362 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKFLCFJD_00363 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
GKFLCFJD_00364 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
GKFLCFJD_00365 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
GKFLCFJD_00366 2.56e-141 - - - M - - - ErfK YbiS YcfS YnhG
GKFLCFJD_00367 6.78e-291 yciC - - S - - - GTPases (G3E family)
GKFLCFJD_00368 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GKFLCFJD_00369 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
GKFLCFJD_00372 5.95e-101 yckC - - S - - - membrane
GKFLCFJD_00373 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
GKFLCFJD_00374 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKFLCFJD_00375 7.06e-93 nin - - S - - - Competence protein J (ComJ)
GKFLCFJD_00376 4.78e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
GKFLCFJD_00377 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKFLCFJD_00378 1.38e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
GKFLCFJD_00379 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
GKFLCFJD_00380 6.05e-86 hxlR - - K - - - transcriptional
GKFLCFJD_00381 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_00382 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_00383 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
GKFLCFJD_00384 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
GKFLCFJD_00385 1.38e-291 - - - EGP - - - Major Facilitator Superfamily
GKFLCFJD_00386 1.61e-126 - - - S - - - YcxB-like protein
GKFLCFJD_00387 1.77e-209 ycxC - - EG - - - EamA-like transporter family
GKFLCFJD_00388 0.0 ycxD - - K - - - GntR family transcriptional regulator
GKFLCFJD_00389 1.37e-144 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
GKFLCFJD_00390 3.04e-148 yczE - - S ko:K07149 - ko00000 membrane
GKFLCFJD_00391 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GKFLCFJD_00392 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GKFLCFJD_00393 1.5e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
GKFLCFJD_00394 9.2e-210 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
GKFLCFJD_00395 2.33e-142 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GKFLCFJD_00396 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
GKFLCFJD_00397 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
GKFLCFJD_00398 3.05e-109 yclD - - - - - - -
GKFLCFJD_00399 5.12e-207 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
GKFLCFJD_00400 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
GKFLCFJD_00401 0.0 yclG - - M - - - Pectate lyase superfamily protein
GKFLCFJD_00403 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
GKFLCFJD_00404 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
GKFLCFJD_00405 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
GKFLCFJD_00406 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GKFLCFJD_00407 5.59e-280 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
GKFLCFJD_00408 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_00409 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GKFLCFJD_00410 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
GKFLCFJD_00412 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
GKFLCFJD_00413 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKFLCFJD_00414 5.42e-206 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_00415 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_00416 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_00417 4.98e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
GKFLCFJD_00418 0.0 ycnB - - EGP - - - the major facilitator superfamily
GKFLCFJD_00419 1.76e-199 ycnC - - K - - - Transcriptional regulator
GKFLCFJD_00420 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GKFLCFJD_00421 1.68e-60 ycnE - - S - - - Monooxygenase
GKFLCFJD_00422 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GKFLCFJD_00423 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKFLCFJD_00424 2.4e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKFLCFJD_00425 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKFLCFJD_00426 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
GKFLCFJD_00427 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_00428 1.07e-138 ycnI - - S - - - protein conserved in bacteria
GKFLCFJD_00429 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
GKFLCFJD_00430 5.18e-139 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GKFLCFJD_00431 1.34e-74 - - - - - - - -
GKFLCFJD_00432 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
GKFLCFJD_00433 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
GKFLCFJD_00434 3.77e-269 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
GKFLCFJD_00435 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
GKFLCFJD_00437 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKFLCFJD_00438 2.64e-147 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
GKFLCFJD_00439 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
GKFLCFJD_00441 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
GKFLCFJD_00442 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
GKFLCFJD_00443 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
GKFLCFJD_00444 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
GKFLCFJD_00445 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
GKFLCFJD_00446 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
GKFLCFJD_00447 3.8e-171 kipR - - K - - - Transcriptional regulator
GKFLCFJD_00448 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
GKFLCFJD_00450 7.67e-66 yczJ - - S - - - biosynthesis
GKFLCFJD_00451 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
GKFLCFJD_00452 3.26e-224 ycsN - - S - - - Oxidoreductase
GKFLCFJD_00453 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
GKFLCFJD_00454 0.0 ydaB - - IQ - - - acyl-CoA ligase
GKFLCFJD_00455 6.05e-129 ydaC - - Q - - - Methyltransferase domain
GKFLCFJD_00456 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_00457 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
GKFLCFJD_00458 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GKFLCFJD_00459 5.24e-101 ydaG - - S - - - general stress protein
GKFLCFJD_00460 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
GKFLCFJD_00461 1.88e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
GKFLCFJD_00462 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
GKFLCFJD_00463 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKFLCFJD_00464 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
GKFLCFJD_00465 1.14e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
GKFLCFJD_00466 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
GKFLCFJD_00467 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
GKFLCFJD_00468 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
GKFLCFJD_00469 0.0 ydaO - - E - - - amino acid
GKFLCFJD_00470 3.75e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GKFLCFJD_00471 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GKFLCFJD_00472 2.14e-53 - - - - - - - -
GKFLCFJD_00473 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GKFLCFJD_00474 1.67e-42 ydaS - - S - - - membrane
GKFLCFJD_00475 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
GKFLCFJD_00476 1.06e-190 ydbA - - P - - - EcsC protein family
GKFLCFJD_00477 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
GKFLCFJD_00478 7.58e-79 ydbB - - G - - - Cupin domain
GKFLCFJD_00479 5.41e-84 ydbC - - S - - - Domain of unknown function (DUF4937
GKFLCFJD_00480 1.35e-198 ydbD - - P ko:K07217 - ko00000 Catalase
GKFLCFJD_00481 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GKFLCFJD_00482 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GKFLCFJD_00483 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
GKFLCFJD_00484 4.43e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKFLCFJD_00485 3.25e-231 ydbI - - S - - - AI-2E family transporter
GKFLCFJD_00486 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_00487 7.34e-160 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GKFLCFJD_00488 9.32e-70 ydbL - - - - - - -
GKFLCFJD_00489 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
GKFLCFJD_00490 1.49e-26 - - - S - - - Fur-regulated basic protein B
GKFLCFJD_00492 1.91e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKFLCFJD_00493 4.19e-75 ydbP - - CO - - - Thioredoxin
GKFLCFJD_00494 3.07e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GKFLCFJD_00495 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKFLCFJD_00496 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKFLCFJD_00497 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
GKFLCFJD_00498 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
GKFLCFJD_00499 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
GKFLCFJD_00500 1.95e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKFLCFJD_00501 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
GKFLCFJD_00502 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKFLCFJD_00503 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
GKFLCFJD_00504 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
GKFLCFJD_00505 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
GKFLCFJD_00506 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
GKFLCFJD_00507 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
GKFLCFJD_00508 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
GKFLCFJD_00509 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
GKFLCFJD_00510 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
GKFLCFJD_00511 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKFLCFJD_00512 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
GKFLCFJD_00516 1.32e-106 ydcG - - S - - - EVE domain
GKFLCFJD_00517 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_00518 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
GKFLCFJD_00519 1.93e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GKFLCFJD_00527 4.41e-270 ydcL - - L - - - Belongs to the 'phage' integrase family
GKFLCFJD_00528 1.41e-119 - - - E - - - IrrE N-terminal-like domain
GKFLCFJD_00529 1.91e-81 - - - K - - - Transcriptional
GKFLCFJD_00530 8.96e-24 - - - - - - - -
GKFLCFJD_00531 9.52e-56 - - - - - - - -
GKFLCFJD_00533 1.84e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
GKFLCFJD_00534 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
GKFLCFJD_00535 2.62e-263 nicK - - L ko:K07467 - ko00000 Replication initiation factor
GKFLCFJD_00538 1.38e-43 yddA - - - - - - -
GKFLCFJD_00539 7.65e-232 yddB - - S - - - Conjugative transposon protein TcpC
GKFLCFJD_00540 3.41e-54 yddC - - - - - - -
GKFLCFJD_00541 7.8e-124 yddD - - S - - - TcpE family
GKFLCFJD_00542 0.0 yddE - - S - - - AAA-like domain
GKFLCFJD_00543 2.81e-74 - - - S - - - Domain of unknown function (DUF1874)
GKFLCFJD_00544 0.0 yddG - - S - - - maturation of SSU-rRNA
GKFLCFJD_00545 4.74e-243 yddH - - M - - - Lysozyme-like
GKFLCFJD_00546 4.05e-114 yddI - - - - - - -
GKFLCFJD_00547 6.67e-86 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
GKFLCFJD_00548 8.08e-192 - - - S - - - TIR domain
GKFLCFJD_00549 5.17e-92 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
GKFLCFJD_00551 2.93e-212 - - - - - - - -
GKFLCFJD_00552 2.43e-241 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKFLCFJD_00553 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
GKFLCFJD_00554 2.17e-102 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
GKFLCFJD_00555 1.62e-128 yddQ - - Q - - - Isochorismatase family
GKFLCFJD_00556 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
GKFLCFJD_00557 3.35e-288 ydeG3 - - EGP - - - Major Facilitator Superfamily
GKFLCFJD_00562 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
GKFLCFJD_00563 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
GKFLCFJD_00564 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
GKFLCFJD_00565 2.47e-47 ydzE - - EG - - - spore germination
GKFLCFJD_00566 3.23e-215 - - - K - - - AraC-like ligand binding domain
GKFLCFJD_00567 4.99e-224 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GKFLCFJD_00568 2.87e-213 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
GKFLCFJD_00569 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKFLCFJD_00570 1.19e-280 ydeG - - EGP - - - Major facilitator superfamily
GKFLCFJD_00571 4.76e-72 ydeH - - - - - - -
GKFLCFJD_00572 1.26e-138 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
GKFLCFJD_00573 6.11e-150 - - - - - - - -
GKFLCFJD_00574 4.66e-197 ydeK - - EG - - - -transporter
GKFLCFJD_00575 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKFLCFJD_00576 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
GKFLCFJD_00577 8.6e-138 - - - S ko:K07002 - ko00000 Serine hydrolase
GKFLCFJD_00578 1.33e-77 - - - K - - - HxlR-like helix-turn-helix
GKFLCFJD_00579 1.68e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKFLCFJD_00580 5.03e-91 ydeP - - K - - - Transcriptional regulator
GKFLCFJD_00581 2.44e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
GKFLCFJD_00582 1.51e-261 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
GKFLCFJD_00583 3.74e-136 ydeS - - K - - - Transcriptional regulator
GKFLCFJD_00584 2.56e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
GKFLCFJD_00585 9.07e-297 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GKFLCFJD_00586 8.05e-191 - - - J - - - GNAT acetyltransferase
GKFLCFJD_00587 3.05e-207 - - - EG - - - EamA-like transporter family
GKFLCFJD_00588 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKFLCFJD_00589 5.97e-151 ydfE - - S - - - Flavin reductase like domain
GKFLCFJD_00590 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GKFLCFJD_00591 1.37e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GKFLCFJD_00593 4.11e-253 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_00594 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKFLCFJD_00595 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
GKFLCFJD_00596 9.73e-226 - - - S - - - Alpha/beta hydrolase family
GKFLCFJD_00597 6.79e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GKFLCFJD_00598 2.13e-189 - - - K - - - Bacterial transcription activator, effector binding domain
GKFLCFJD_00599 3.15e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKFLCFJD_00600 3.45e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
GKFLCFJD_00601 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GKFLCFJD_00602 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
GKFLCFJD_00603 9.63e-77 ydfQ - - CO - - - Thioredoxin
GKFLCFJD_00604 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
GKFLCFJD_00605 5.33e-39 - - - - - - - -
GKFLCFJD_00607 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
GKFLCFJD_00608 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
GKFLCFJD_00609 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKFLCFJD_00610 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
GKFLCFJD_00611 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
GKFLCFJD_00612 7.86e-132 ydgC - - K - - - Bacterial regulatory proteins, tetR family
GKFLCFJD_00613 4.21e-72 - - - S - - - DoxX-like family
GKFLCFJD_00614 2.49e-114 yycN - - K - - - Acetyltransferase
GKFLCFJD_00615 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
GKFLCFJD_00616 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GKFLCFJD_00617 5.09e-119 - - - S - - - DinB family
GKFLCFJD_00618 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_00619 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
GKFLCFJD_00620 6.42e-147 ydgI - - C - - - nitroreductase
GKFLCFJD_00621 1.15e-90 - - - K - - - Winged helix DNA-binding domain
GKFLCFJD_00622 5.97e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
GKFLCFJD_00623 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
GKFLCFJD_00624 5.24e-158 ydhC - - K - - - FCD
GKFLCFJD_00625 8.92e-310 ydhD - - M - - - Glycosyl hydrolase
GKFLCFJD_00626 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GKFLCFJD_00627 7.71e-166 - - - - - - - -
GKFLCFJD_00628 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
GKFLCFJD_00629 9.93e-91 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
GKFLCFJD_00631 1.43e-112 - - - K - - - Acetyltransferase (GNAT) domain
GKFLCFJD_00632 1.25e-236 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKFLCFJD_00633 4.01e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
GKFLCFJD_00634 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
GKFLCFJD_00635 7.97e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_00636 6.09e-70 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_00637 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKFLCFJD_00638 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKFLCFJD_00639 1.9e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
GKFLCFJD_00640 9.28e-219 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
GKFLCFJD_00641 1.93e-244 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKFLCFJD_00642 3.49e-273 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
GKFLCFJD_00643 1.12e-98 ydhU - - P ko:K07217 - ko00000 Catalase
GKFLCFJD_00644 7.94e-22 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
GKFLCFJD_00647 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00650 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GKFLCFJD_00651 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
GKFLCFJD_00652 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
GKFLCFJD_00653 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GKFLCFJD_00654 1.63e-241 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKFLCFJD_00655 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
GKFLCFJD_00656 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GKFLCFJD_00657 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKFLCFJD_00658 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GKFLCFJD_00659 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKFLCFJD_00660 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
GKFLCFJD_00661 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKFLCFJD_00662 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKFLCFJD_00663 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKFLCFJD_00665 6.93e-88 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
GKFLCFJD_00666 0.0 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
GKFLCFJD_00667 1.43e-297 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
GKFLCFJD_00669 3.67e-254 - - - V - - - AAA domain (dynein-related subfamily)
GKFLCFJD_00670 0.0 - - - J - - - LlaJI restriction endonuclease
GKFLCFJD_00671 3.73e-11 ydjC - - S - - - Abhydrolase domain containing 18
GKFLCFJD_00672 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
GKFLCFJD_00673 1.06e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
GKFLCFJD_00674 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
GKFLCFJD_00675 5.39e-224 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
GKFLCFJD_00676 5.36e-148 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
GKFLCFJD_00677 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKFLCFJD_00678 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
GKFLCFJD_00679 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
GKFLCFJD_00680 1.37e-248 - - - S - - - Ion transport 2 domain protein
GKFLCFJD_00681 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKFLCFJD_00682 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
GKFLCFJD_00683 1.79e-84 ydjM - - M - - - Lytic transglycolase
GKFLCFJD_00684 3.76e-213 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
GKFLCFJD_00686 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
GKFLCFJD_00687 3.21e-205 - - - I - - - Alpha/beta hydrolase family
GKFLCFJD_00688 1.9e-233 yeaA - - S - - - Protein of unknown function (DUF4003)
GKFLCFJD_00689 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
GKFLCFJD_00690 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GKFLCFJD_00691 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKFLCFJD_00692 1.18e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
GKFLCFJD_00693 6.74e-287 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
GKFLCFJD_00694 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
GKFLCFJD_00695 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GKFLCFJD_00696 1.2e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKFLCFJD_00697 1.44e-165 yebC - - M - - - Membrane
GKFLCFJD_00699 2.66e-120 yebE - - S - - - UPF0316 protein
GKFLCFJD_00700 3.13e-38 yebG - - S - - - NETI protein
GKFLCFJD_00701 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKFLCFJD_00702 9.39e-278 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKFLCFJD_00703 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKFLCFJD_00704 1.06e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GKFLCFJD_00705 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKFLCFJD_00706 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKFLCFJD_00707 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKFLCFJD_00708 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GKFLCFJD_00709 4.2e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GKFLCFJD_00710 4.4e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKFLCFJD_00711 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GKFLCFJD_00712 2.07e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GKFLCFJD_00713 5.26e-96 - - - K - - - helix_turn_helix ASNC type
GKFLCFJD_00714 1.91e-297 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
GKFLCFJD_00715 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
GKFLCFJD_00716 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
GKFLCFJD_00717 7.03e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
GKFLCFJD_00718 7.62e-68 yerC - - S - - - protein conserved in bacteria
GKFLCFJD_00719 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
GKFLCFJD_00721 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GKFLCFJD_00722 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GKFLCFJD_00723 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKFLCFJD_00724 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
GKFLCFJD_00725 6.28e-253 yerI - - S - - - homoserine kinase type II (protein kinase fold)
GKFLCFJD_00726 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
GKFLCFJD_00727 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKFLCFJD_00728 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKFLCFJD_00729 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKFLCFJD_00730 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKFLCFJD_00731 2.93e-201 yerO - - K - - - Transcriptional regulator
GKFLCFJD_00732 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GKFLCFJD_00733 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GKFLCFJD_00734 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKFLCFJD_00735 3.63e-127 - - - L - - - Recombinase
GKFLCFJD_00736 5.61e-71 - - - L - - - Resolvase, N terminal domain
GKFLCFJD_00737 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
GKFLCFJD_00738 0.0 - - - L - - - DEAD-like helicases superfamily
GKFLCFJD_00739 1.37e-271 yeeC - - P - - - T5orf172
GKFLCFJD_00740 7.48e-05 - - - - - - - -
GKFLCFJD_00741 4.15e-42 - - - S - - - Colicin immunity protein / pyocin immunity protein
GKFLCFJD_00742 2.1e-109 - - - S - - - Protein of unknown function, DUF600
GKFLCFJD_00743 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
GKFLCFJD_00744 1.73e-246 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
GKFLCFJD_00745 1.33e-275 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
GKFLCFJD_00747 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
GKFLCFJD_00749 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_00750 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
GKFLCFJD_00751 8.81e-206 yesF - - GM - - - NAD(P)H-binding
GKFLCFJD_00752 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
GKFLCFJD_00753 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
GKFLCFJD_00754 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
GKFLCFJD_00755 1.76e-132 yesJ - - K - - - Acetyltransferase (GNAT) family
GKFLCFJD_00757 3.52e-135 yesL - - S - - - Protein of unknown function, DUF624
GKFLCFJD_00758 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_00759 5.07e-260 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
GKFLCFJD_00760 8.76e-316 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKFLCFJD_00761 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKFLCFJD_00762 1.31e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKFLCFJD_00763 6.85e-255 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
GKFLCFJD_00764 0.0 yesS - - K - - - Transcriptional regulator
GKFLCFJD_00765 3.56e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKFLCFJD_00766 1.41e-169 yesU - - S - - - Domain of unknown function (DUF1961)
GKFLCFJD_00767 3.44e-146 - - - S - - - Protein of unknown function, DUF624
GKFLCFJD_00768 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
GKFLCFJD_00769 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
GKFLCFJD_00770 9.13e-160 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKFLCFJD_00771 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
GKFLCFJD_00772 0.0 yetA - - - - - - -
GKFLCFJD_00773 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKFLCFJD_00774 1.01e-227 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
GKFLCFJD_00775 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKFLCFJD_00776 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
GKFLCFJD_00777 3.13e-158 yetF - - S - - - membrane
GKFLCFJD_00778 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
GKFLCFJD_00779 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKFLCFJD_00780 9.79e-45 - - - - - - - -
GKFLCFJD_00781 3.87e-114 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKFLCFJD_00782 1.97e-54 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKFLCFJD_00783 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
GKFLCFJD_00784 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKFLCFJD_00785 7.35e-203 - - - EG - - - EamA-like transporter family
GKFLCFJD_00786 6.74e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_00787 4.77e-270 yetM - - CH - - - FAD binding domain
GKFLCFJD_00788 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
GKFLCFJD_00789 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
GKFLCFJD_00790 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GKFLCFJD_00791 2.15e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
GKFLCFJD_00792 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
GKFLCFJD_00793 9.79e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
GKFLCFJD_00794 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
GKFLCFJD_00795 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
GKFLCFJD_00796 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_00797 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GKFLCFJD_00798 4.16e-313 yfnA - - E ko:K03294 - ko00000 amino acid
GKFLCFJD_00799 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKFLCFJD_00800 5.14e-161 yfmS - - NT - - - chemotaxis protein
GKFLCFJD_00801 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GKFLCFJD_00802 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
GKFLCFJD_00803 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
GKFLCFJD_00804 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
GKFLCFJD_00805 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GKFLCFJD_00806 1.86e-266 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
GKFLCFJD_00807 1.86e-107 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
GKFLCFJD_00808 4.21e-242 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
GKFLCFJD_00809 1.72e-268 - - - G - - - Major Facilitator Superfamily
GKFLCFJD_00810 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
GKFLCFJD_00811 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
GKFLCFJD_00812 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_00813 2.85e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_00814 2.88e-221 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
GKFLCFJD_00815 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
GKFLCFJD_00816 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
GKFLCFJD_00817 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
GKFLCFJD_00818 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GKFLCFJD_00819 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GKFLCFJD_00820 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GKFLCFJD_00821 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
GKFLCFJD_00823 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GKFLCFJD_00824 7.21e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GKFLCFJD_00825 1.43e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GKFLCFJD_00826 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GKFLCFJD_00827 2.51e-159 yflK - - S - - - protein conserved in bacteria
GKFLCFJD_00828 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
GKFLCFJD_00829 6.9e-27 yflI - - - - - - -
GKFLCFJD_00830 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
GKFLCFJD_00831 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
GKFLCFJD_00832 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GKFLCFJD_00833 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GKFLCFJD_00834 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
GKFLCFJD_00835 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
GKFLCFJD_00836 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
GKFLCFJD_00838 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
GKFLCFJD_00839 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
GKFLCFJD_00840 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_00841 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
GKFLCFJD_00842 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
GKFLCFJD_00843 5.27e-161 frp - - C - - - nitroreductase
GKFLCFJD_00844 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKFLCFJD_00845 8.44e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
GKFLCFJD_00846 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_00847 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
GKFLCFJD_00848 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKFLCFJD_00849 2.53e-67 yfkI - - S - - - gas vesicle protein
GKFLCFJD_00850 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GKFLCFJD_00851 1.64e-12 - - - - - - - -
GKFLCFJD_00852 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_00853 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
GKFLCFJD_00854 3.69e-189 yfkD - - S - - - YfkD-like protein
GKFLCFJD_00855 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
GKFLCFJD_00856 1.76e-283 yfkA - - S - - - YfkB-like domain
GKFLCFJD_00857 3.26e-36 yfjT - - - - - - -
GKFLCFJD_00858 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
GKFLCFJD_00859 4.82e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
GKFLCFJD_00860 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
GKFLCFJD_00861 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GKFLCFJD_00862 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKFLCFJD_00863 3e-53 - - - S - - - YfzA-like protein
GKFLCFJD_00864 1.21e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKFLCFJD_00865 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
GKFLCFJD_00867 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GKFLCFJD_00868 2.75e-244 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GKFLCFJD_00869 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKFLCFJD_00870 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GKFLCFJD_00871 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
GKFLCFJD_00872 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
GKFLCFJD_00873 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
GKFLCFJD_00874 1.53e-104 - - - S - - - Family of unknown function (DUF5381)
GKFLCFJD_00875 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
GKFLCFJD_00876 2.5e-185 yfjC - - - - - - -
GKFLCFJD_00877 1.94e-270 yfjB - - - - - - -
GKFLCFJD_00878 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
GKFLCFJD_00879 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GKFLCFJD_00880 6.12e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GKFLCFJD_00881 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_00882 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
GKFLCFJD_00883 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKFLCFJD_00884 2.01e-84 yfiD3 - - S - - - DoxX
GKFLCFJD_00885 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
GKFLCFJD_00886 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
GKFLCFJD_00887 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKFLCFJD_00888 5.47e-234 - - - G - - - Xylose isomerase
GKFLCFJD_00889 5.17e-295 - - - S - - - Oxidoreductase
GKFLCFJD_00891 7.54e-276 baeS - - T - - - Histidine kinase
GKFLCFJD_00892 1.05e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
GKFLCFJD_00893 3.35e-218 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_00894 3.66e-274 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GKFLCFJD_00895 4.56e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
GKFLCFJD_00896 1.89e-128 padR - - K - - - transcriptional
GKFLCFJD_00897 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
GKFLCFJD_00898 2.29e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GKFLCFJD_00899 4.18e-141 yfiR - - K - - - Transcriptional regulator
GKFLCFJD_00900 4.51e-281 yfiS - - EGP - - - Major facilitator superfamily
GKFLCFJD_00901 2.41e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
GKFLCFJD_00902 0.0 yfiU - - EGP - - - the major facilitator superfamily
GKFLCFJD_00903 5.39e-106 yfiV - - K - - - transcriptional
GKFLCFJD_00904 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKFLCFJD_00905 2.81e-233 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKFLCFJD_00906 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_00907 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_00908 7.61e-215 yfhB - - S - - - PhzF family
GKFLCFJD_00909 2.87e-138 yfhC - - C - - - nitroreductase
GKFLCFJD_00910 8.86e-35 yfhD - - S - - - YfhD-like protein
GKFLCFJD_00912 1.13e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
GKFLCFJD_00913 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
GKFLCFJD_00914 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
GKFLCFJD_00916 2.45e-268 yfhI - - EGP - - - -transporter
GKFLCFJD_00917 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
GKFLCFJD_00918 8.95e-60 yfhJ - - S - - - WVELL protein
GKFLCFJD_00919 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
GKFLCFJD_00920 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
GKFLCFJD_00921 3.37e-219 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
GKFLCFJD_00922 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GKFLCFJD_00923 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
GKFLCFJD_00924 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
GKFLCFJD_00925 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
GKFLCFJD_00926 1.73e-48 yfhS - - - - - - -
GKFLCFJD_00927 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_00928 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
GKFLCFJD_00929 2.01e-49 ygaB - - S - - - YgaB-like protein
GKFLCFJD_00930 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
GKFLCFJD_00931 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
GKFLCFJD_00932 1.87e-238 ygaE - - S - - - Membrane
GKFLCFJD_00933 1.19e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
GKFLCFJD_00934 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
GKFLCFJD_00935 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GKFLCFJD_00936 4.67e-75 ygzB - - S - - - UPF0295 protein
GKFLCFJD_00937 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
GKFLCFJD_00938 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_00955 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
GKFLCFJD_00956 3.88e-37 - - - - - - - -
GKFLCFJD_00957 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
GKFLCFJD_00958 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GKFLCFJD_00959 0.0 ygaK - - C - - - Berberine and berberine like
GKFLCFJD_00961 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GKFLCFJD_00962 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GKFLCFJD_00963 1.78e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
GKFLCFJD_00964 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GKFLCFJD_00965 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
GKFLCFJD_00967 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKFLCFJD_00968 2.79e-102 ygaO - - - - - - -
GKFLCFJD_00969 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_00971 1.92e-147 yhzB - - S - - - B3/4 domain
GKFLCFJD_00972 5.09e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GKFLCFJD_00973 4.79e-226 yhbB - - S - - - Putative amidase domain
GKFLCFJD_00974 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKFLCFJD_00975 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
GKFLCFJD_00976 2.29e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
GKFLCFJD_00977 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
GKFLCFJD_00978 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
GKFLCFJD_00979 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
GKFLCFJD_00980 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
GKFLCFJD_00981 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
GKFLCFJD_00982 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
GKFLCFJD_00983 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
GKFLCFJD_00984 3.95e-59 yhcC - - - - - - -
GKFLCFJD_00985 2.92e-69 - - - - - - - -
GKFLCFJD_00986 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_00987 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_00988 6.47e-213 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_00989 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GKFLCFJD_00990 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
GKFLCFJD_00991 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKFLCFJD_00992 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
GKFLCFJD_00993 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKFLCFJD_00994 3.23e-80 yhcM - - - - - - -
GKFLCFJD_00995 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GKFLCFJD_00996 3.96e-227 yhcP - - - - - - -
GKFLCFJD_00997 1.68e-146 yhcQ - - M - - - Spore coat protein
GKFLCFJD_00998 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKFLCFJD_00999 3.9e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
GKFLCFJD_01000 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GKFLCFJD_01001 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
GKFLCFJD_01002 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
GKFLCFJD_01003 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
GKFLCFJD_01004 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GKFLCFJD_01005 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKFLCFJD_01006 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GKFLCFJD_01007 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GKFLCFJD_01008 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKFLCFJD_01009 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GKFLCFJD_01010 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
GKFLCFJD_01011 2.29e-273 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_01012 5.68e-148 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKFLCFJD_01013 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
GKFLCFJD_01014 1.65e-51 yhdB - - S - - - YhdB-like protein
GKFLCFJD_01015 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
GKFLCFJD_01016 2.4e-275 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GKFLCFJD_01017 1.37e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
GKFLCFJD_01018 5.29e-307 ygxB - - M - - - Conserved TM helix
GKFLCFJD_01019 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
GKFLCFJD_01020 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
GKFLCFJD_01021 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GKFLCFJD_01022 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_01023 5.51e-263 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GKFLCFJD_01024 1.41e-208 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_01025 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
GKFLCFJD_01026 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GKFLCFJD_01027 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKFLCFJD_01028 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKFLCFJD_01029 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
GKFLCFJD_01030 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
GKFLCFJD_01031 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_01032 6.74e-244 yhdN - - C - - - Aldo keto reductase
GKFLCFJD_01033 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GKFLCFJD_01034 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GKFLCFJD_01035 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
GKFLCFJD_01036 4.37e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GKFLCFJD_01037 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
GKFLCFJD_01038 2.69e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKFLCFJD_01039 1.01e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKFLCFJD_01040 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GKFLCFJD_01041 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
GKFLCFJD_01042 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
GKFLCFJD_01043 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GKFLCFJD_01044 5.7e-200 nodB1 - - G - - - deacetylase
GKFLCFJD_01045 2.23e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
GKFLCFJD_01046 3.94e-307 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
GKFLCFJD_01047 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
GKFLCFJD_01048 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKFLCFJD_01049 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKFLCFJD_01050 3.31e-143 yheG - - GM - - - NAD(P)H-binding
GKFLCFJD_01051 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
GKFLCFJD_01052 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
GKFLCFJD_01053 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
GKFLCFJD_01054 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
GKFLCFJD_01055 1.51e-261 yheB - - S - - - Belongs to the UPF0754 family
GKFLCFJD_01056 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
GKFLCFJD_01057 6.69e-264 yhaZ - - L - - - DNA alkylation repair enzyme
GKFLCFJD_01058 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
GKFLCFJD_01059 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
GKFLCFJD_01060 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
GKFLCFJD_01061 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
GKFLCFJD_01063 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
GKFLCFJD_01064 2.29e-36 - - - S - - - YhzD-like protein
GKFLCFJD_01065 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_01066 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
GKFLCFJD_01067 9.85e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
GKFLCFJD_01068 0.0 yhaN - - L - - - AAA domain
GKFLCFJD_01069 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
GKFLCFJD_01070 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
GKFLCFJD_01071 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GKFLCFJD_01072 1.4e-116 yhaK - - S - - - Putative zincin peptidase
GKFLCFJD_01073 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
GKFLCFJD_01074 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
GKFLCFJD_01075 1.74e-54 yhaH - - S - - - YtxH-like protein
GKFLCFJD_01076 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
GKFLCFJD_01077 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GKFLCFJD_01078 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GKFLCFJD_01079 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
GKFLCFJD_01080 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GKFLCFJD_01081 5e-162 ecsC - - S - - - EcsC protein family
GKFLCFJD_01082 4.8e-295 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GKFLCFJD_01083 8.98e-317 yhfA - - C - - - membrane
GKFLCFJD_01084 1.33e-23 - - - C - - - Rubrerythrin
GKFLCFJD_01085 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
GKFLCFJD_01086 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKFLCFJD_01087 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GKFLCFJD_01088 2.06e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GKFLCFJD_01089 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GKFLCFJD_01090 3.49e-133 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_01091 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
GKFLCFJD_01092 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKFLCFJD_01093 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
GKFLCFJD_01094 2.68e-253 yhfE - - G - - - peptidase M42
GKFLCFJD_01095 3.75e-94 - - - S - - - ASCH
GKFLCFJD_01096 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKFLCFJD_01097 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
GKFLCFJD_01098 1.21e-246 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GKFLCFJD_01099 1.82e-144 yhfK - - GM - - - NmrA-like family
GKFLCFJD_01100 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
GKFLCFJD_01101 2.78e-85 yhfM - - - - - - -
GKFLCFJD_01102 9.64e-308 yhfN - - O - - - Peptidase M48
GKFLCFJD_01103 2.94e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKFLCFJD_01104 2.75e-105 - - - K - - - acetyltransferase
GKFLCFJD_01105 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
GKFLCFJD_01106 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GKFLCFJD_01107 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
GKFLCFJD_01108 1.19e-256 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GKFLCFJD_01109 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
GKFLCFJD_01110 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
GKFLCFJD_01111 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
GKFLCFJD_01112 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
GKFLCFJD_01113 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_01114 9.84e-45 yhzC - - S - - - IDEAL
GKFLCFJD_01115 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
GKFLCFJD_01116 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GKFLCFJD_01117 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
GKFLCFJD_01118 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKFLCFJD_01119 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
GKFLCFJD_01120 2.57e-78 yhjD - - - - - - -
GKFLCFJD_01121 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
GKFLCFJD_01122 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKFLCFJD_01123 0.0 yhjG - - CH - - - FAD binding domain
GKFLCFJD_01124 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_01125 3.12e-273 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
GKFLCFJD_01126 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
GKFLCFJD_01127 2.63e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
GKFLCFJD_01128 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
GKFLCFJD_01129 2.63e-240 yhjM - - K - - - Transcriptional regulator
GKFLCFJD_01130 2.14e-260 yhjN - - S ko:K07120 - ko00000 membrane
GKFLCFJD_01131 1.27e-272 - - - EGP - - - Transmembrane secretion effector
GKFLCFJD_01132 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
GKFLCFJD_01133 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
GKFLCFJD_01134 9.3e-102 yhjR - - S - - - Rubrerythrin
GKFLCFJD_01135 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
GKFLCFJD_01136 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GKFLCFJD_01137 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GKFLCFJD_01138 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
GKFLCFJD_01139 1.34e-66 yisB - - V - - - COG1403 Restriction endonuclease
GKFLCFJD_01140 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
GKFLCFJD_01141 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
GKFLCFJD_01142 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
GKFLCFJD_01143 8.23e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
GKFLCFJD_01144 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
GKFLCFJD_01145 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
GKFLCFJD_01146 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
GKFLCFJD_01147 3.96e-224 cotH - - M ko:K06330 - ko00000 Spore Coat
GKFLCFJD_01148 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
GKFLCFJD_01149 1.02e-74 yisL - - S - - - UPF0344 protein
GKFLCFJD_01150 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKFLCFJD_01151 7.48e-137 yisN - - S - - - Protein of unknown function (DUF2777)
GKFLCFJD_01152 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GKFLCFJD_01153 1.85e-115 yizA - - S - - - Damage-inducible protein DinB
GKFLCFJD_01154 6.82e-193 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
GKFLCFJD_01155 1.01e-310 yisQ - - V - - - Mate efflux family protein
GKFLCFJD_01156 1.41e-207 yisR - - K - - - Transcriptional regulator
GKFLCFJD_01157 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GKFLCFJD_01158 9.72e-254 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
GKFLCFJD_01159 7.28e-122 yisT - - S - - - DinB family
GKFLCFJD_01160 5.42e-140 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
GKFLCFJD_01161 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKFLCFJD_01162 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
GKFLCFJD_01163 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GKFLCFJD_01164 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
GKFLCFJD_01165 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
GKFLCFJD_01166 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
GKFLCFJD_01167 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
GKFLCFJD_01168 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
GKFLCFJD_01169 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKFLCFJD_01170 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GKFLCFJD_01171 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_01172 7.86e-207 yitH - - K - - - Acetyltransferase (GNAT) domain
GKFLCFJD_01173 8.19e-107 - - - S - - - Acetyltransferase (GNAT) domain
GKFLCFJD_01174 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GKFLCFJD_01175 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
GKFLCFJD_01176 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
GKFLCFJD_01177 4.16e-122 - - - - - - - -
GKFLCFJD_01178 1.42e-218 - - - - - - - -
GKFLCFJD_01179 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
GKFLCFJD_01180 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
GKFLCFJD_01181 7.76e-123 - - - - - - - -
GKFLCFJD_01182 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
GKFLCFJD_01183 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
GKFLCFJD_01184 9.13e-202 yitS - - S - - - protein conserved in bacteria
GKFLCFJD_01185 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKFLCFJD_01186 1.61e-92 ipi - - S - - - Intracellular proteinase inhibitor
GKFLCFJD_01187 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
GKFLCFJD_01188 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GKFLCFJD_01189 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
GKFLCFJD_01190 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
GKFLCFJD_01191 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
GKFLCFJD_01192 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
GKFLCFJD_01193 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
GKFLCFJD_01194 9.02e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GKFLCFJD_01195 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GKFLCFJD_01196 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
GKFLCFJD_01197 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
GKFLCFJD_01198 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKFLCFJD_01199 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
GKFLCFJD_01200 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKFLCFJD_01201 2.51e-39 yjzC - - S - - - YjzC-like protein
GKFLCFJD_01202 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
GKFLCFJD_01203 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
GKFLCFJD_01204 5.41e-134 yjaV - - - - - - -
GKFLCFJD_01205 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
GKFLCFJD_01206 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
GKFLCFJD_01207 2.67e-38 yjzB - - - - - - -
GKFLCFJD_01208 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKFLCFJD_01209 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GKFLCFJD_01210 9.48e-193 yjaZ - - O - - - Zn-dependent protease
GKFLCFJD_01211 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKFLCFJD_01212 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKFLCFJD_01213 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
GKFLCFJD_01214 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKFLCFJD_01215 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKFLCFJD_01216 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
GKFLCFJD_01217 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
GKFLCFJD_01218 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKFLCFJD_01219 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKFLCFJD_01220 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKFLCFJD_01221 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKFLCFJD_01222 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKFLCFJD_01223 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
GKFLCFJD_01224 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKFLCFJD_01225 3.51e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKFLCFJD_01226 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
GKFLCFJD_01227 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GKFLCFJD_01228 1.31e-283 coiA - - S ko:K06198 - ko00000 Competence protein
GKFLCFJD_01229 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GKFLCFJD_01230 2.68e-28 - - - - - - - -
GKFLCFJD_01232 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
GKFLCFJD_01233 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
GKFLCFJD_01234 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GKFLCFJD_01235 5.15e-130 yjbK - - S - - - protein conserved in bacteria
GKFLCFJD_01236 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
GKFLCFJD_01237 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
GKFLCFJD_01238 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKFLCFJD_01239 9.4e-206 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GKFLCFJD_01240 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
GKFLCFJD_01241 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GKFLCFJD_01242 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GKFLCFJD_01243 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
GKFLCFJD_01244 1.14e-277 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
GKFLCFJD_01245 5.35e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
GKFLCFJD_01246 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GKFLCFJD_01247 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GKFLCFJD_01248 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GKFLCFJD_01249 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
GKFLCFJD_01250 2.32e-107 yjbX - - S - - - Spore coat protein
GKFLCFJD_01251 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
GKFLCFJD_01252 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
GKFLCFJD_01253 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
GKFLCFJD_01254 1.08e-54 cotW - - - ko:K06341 - ko00000 -
GKFLCFJD_01255 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
GKFLCFJD_01256 3.03e-76 yjcA - - S - - - Protein of unknown function (DUF1360)
GKFLCFJD_01259 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
GKFLCFJD_01260 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKFLCFJD_01261 6.31e-51 - - - - - - - -
GKFLCFJD_01262 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKFLCFJD_01263 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
GKFLCFJD_01264 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
GKFLCFJD_01265 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GKFLCFJD_01266 6.4e-281 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GKFLCFJD_01267 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
GKFLCFJD_01268 2.58e-274 yjcL - - S - - - Protein of unknown function (DUF819)
GKFLCFJD_01271 3.75e-269 - - - S - - - Putative amidase domain
GKFLCFJD_01272 1.52e-68 yjcN - - - - - - -
GKFLCFJD_01275 2.24e-106 - - - L - - - Transposase
GKFLCFJD_01276 5.68e-100 yjcP - - - - - - -
GKFLCFJD_01277 1.01e-65 - - - S - - - YjcQ protein
GKFLCFJD_01278 3.29e-121 yqaS - - L - - - DNA packaging
GKFLCFJD_01279 3.8e-63 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
GKFLCFJD_01280 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GKFLCFJD_01281 0.000759 - - - - - - - -
GKFLCFJD_01282 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
GKFLCFJD_01283 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_01284 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKFLCFJD_01285 4.79e-78 yjdF3 - - S - - - Protein of unknown function (DUF2992)
GKFLCFJD_01286 1.36e-121 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKFLCFJD_01288 1.01e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKFLCFJD_01289 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
GKFLCFJD_01290 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
GKFLCFJD_01291 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GKFLCFJD_01293 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
GKFLCFJD_01294 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
GKFLCFJD_01295 1.95e-30 yjfB - - S - - - Putative motility protein
GKFLCFJD_01296 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
GKFLCFJD_01297 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
GKFLCFJD_01298 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
GKFLCFJD_01299 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
GKFLCFJD_01300 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
GKFLCFJD_01302 1.91e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GKFLCFJD_01304 1.48e-289 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKFLCFJD_01305 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GKFLCFJD_01306 1.11e-41 - - - - - - - -
GKFLCFJD_01307 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
GKFLCFJD_01308 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
GKFLCFJD_01309 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKFLCFJD_01310 1.09e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
GKFLCFJD_01311 8.91e-121 yjlB - - S - - - Cupin domain
GKFLCFJD_01312 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
GKFLCFJD_01313 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKFLCFJD_01314 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
GKFLCFJD_01315 6.34e-316 - - - G ko:K03292 - ko00000 symporter YjmB
GKFLCFJD_01316 2.02e-248 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
GKFLCFJD_01317 1.6e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
GKFLCFJD_01318 1.66e-274 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
GKFLCFJD_01319 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_01320 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
GKFLCFJD_01321 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
GKFLCFJD_01322 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
GKFLCFJD_01323 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
GKFLCFJD_01324 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
GKFLCFJD_01325 4.87e-106 yjoA - - S - - - DinB family
GKFLCFJD_01326 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
GKFLCFJD_01327 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
GKFLCFJD_01329 1.79e-55 - - - S - - - YCII-related domain
GKFLCFJD_01330 1.37e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
GKFLCFJD_01331 3.31e-81 yjqA - - S - - - Bacterial PH domain
GKFLCFJD_01332 1.47e-143 yjqB - - S - - - Pfam:DUF867
GKFLCFJD_01333 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
GKFLCFJD_01334 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
GKFLCFJD_01335 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
GKFLCFJD_01337 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
GKFLCFJD_01338 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
GKFLCFJD_01342 5.95e-112 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GKFLCFJD_01343 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
GKFLCFJD_01344 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
GKFLCFJD_01345 0.0 yqbA - - S - - - portal protein
GKFLCFJD_01346 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
GKFLCFJD_01347 3.91e-217 xkdG - - S - - - Phage capsid family
GKFLCFJD_01348 2.06e-85 yqbG - - S - - - Protein of unknown function (DUF3199)
GKFLCFJD_01349 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
GKFLCFJD_01350 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
GKFLCFJD_01351 2.87e-101 xkdJ - - - - - - -
GKFLCFJD_01352 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
GKFLCFJD_01353 6.01e-99 xkdM - - S - - - Phage tail tube protein
GKFLCFJD_01354 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
GKFLCFJD_01355 0.0 xkdO - - L - - - Transglycosylase SLT domain
GKFLCFJD_01356 1.77e-158 xkdP - - S - - - Lysin motif
GKFLCFJD_01357 2.31e-232 xkdQ - - G - - - NLP P60 protein
GKFLCFJD_01358 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
GKFLCFJD_01359 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
GKFLCFJD_01360 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GKFLCFJD_01361 9.63e-136 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
GKFLCFJD_01362 4.43e-56 - - - - - - - -
GKFLCFJD_01363 0.0 - - - - - - - -
GKFLCFJD_01364 8.68e-74 xkdW - - S - - - XkdW protein
GKFLCFJD_01365 9.34e-33 xkdX - - - - - - -
GKFLCFJD_01366 1.51e-198 xepA - - - - - - -
GKFLCFJD_01367 7.71e-52 xhlA - - S - - - Haemolysin XhlA
GKFLCFJD_01368 8.12e-53 xhlB - - S - - - SPP1 phage holin
GKFLCFJD_01369 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
GKFLCFJD_01370 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
GKFLCFJD_01371 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
GKFLCFJD_01372 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
GKFLCFJD_01373 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
GKFLCFJD_01374 7.7e-311 steT - - E ko:K03294 - ko00000 amino acid
GKFLCFJD_01375 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GKFLCFJD_01377 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKFLCFJD_01378 1.34e-230 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GKFLCFJD_01380 6.72e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKFLCFJD_01381 1.54e-183 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
GKFLCFJD_01382 2.42e-197 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
GKFLCFJD_01383 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKFLCFJD_01384 6.35e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKFLCFJD_01385 6.22e-242 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKFLCFJD_01386 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKFLCFJD_01388 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
GKFLCFJD_01389 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GKFLCFJD_01390 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GKFLCFJD_01391 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKFLCFJD_01392 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
GKFLCFJD_01393 4.37e-206 ykgA - - E - - - Amidinotransferase
GKFLCFJD_01394 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
GKFLCFJD_01395 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GKFLCFJD_01396 5.85e-13 - - - - - - - -
GKFLCFJD_01397 4.81e-168 ykjA - - S - - - Protein of unknown function (DUF421)
GKFLCFJD_01398 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
GKFLCFJD_01399 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GKFLCFJD_01400 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
GKFLCFJD_01401 2.86e-68 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
GKFLCFJD_01402 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
GKFLCFJD_01403 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKFLCFJD_01404 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKFLCFJD_01405 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
GKFLCFJD_01406 1.21e-98 ohrR - - K - - - COG1846 Transcriptional regulators
GKFLCFJD_01407 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
GKFLCFJD_01409 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
GKFLCFJD_01410 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GKFLCFJD_01411 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKFLCFJD_01412 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKFLCFJD_01413 3.8e-175 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GKFLCFJD_01414 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_01415 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GKFLCFJD_01416 7.28e-144 ykoF - - S - - - YKOF-related Family
GKFLCFJD_01417 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_01418 8.05e-312 ykoH - - T - - - Histidine kinase
GKFLCFJD_01419 3.35e-146 ykoI - - S - - - Peptidase propeptide and YPEB domain
GKFLCFJD_01420 2.24e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GKFLCFJD_01421 1.45e-08 - - - - - - - -
GKFLCFJD_01423 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
GKFLCFJD_01424 1.49e-70 tnrA - - K - - - transcriptional
GKFLCFJD_01425 1.63e-25 - - - - - - - -
GKFLCFJD_01426 3.04e-36 ykoL - - - - - - -
GKFLCFJD_01427 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
GKFLCFJD_01428 1.19e-281 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
GKFLCFJD_01429 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
GKFLCFJD_01430 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
GKFLCFJD_01431 0.0 ykoS - - - - - - -
GKFLCFJD_01432 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
GKFLCFJD_01433 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
GKFLCFJD_01434 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GKFLCFJD_01435 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
GKFLCFJD_01436 4.48e-153 ykoX - - S - - - membrane-associated protein
GKFLCFJD_01437 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GKFLCFJD_01438 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKFLCFJD_01439 9.33e-219 rsgI - - S - - - Anti-sigma factor N-terminus
GKFLCFJD_01440 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
GKFLCFJD_01441 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
GKFLCFJD_01442 3.4e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GKFLCFJD_01443 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
GKFLCFJD_01445 8.33e-31 ykzE - - - - - - -
GKFLCFJD_01446 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
GKFLCFJD_01447 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_01448 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKFLCFJD_01450 1.62e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GKFLCFJD_01451 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GKFLCFJD_01452 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GKFLCFJD_01453 4.81e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKFLCFJD_01454 3.39e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
GKFLCFJD_01455 1.07e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GKFLCFJD_01456 4.52e-147 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
GKFLCFJD_01457 1.5e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GKFLCFJD_01458 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
GKFLCFJD_01460 5.84e-95 eag - - - - - - -
GKFLCFJD_01461 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GKFLCFJD_01462 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
GKFLCFJD_01463 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
GKFLCFJD_01464 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
GKFLCFJD_01465 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
GKFLCFJD_01466 4.26e-230 ykvI - - S - - - membrane
GKFLCFJD_01467 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GKFLCFJD_01468 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
GKFLCFJD_01469 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GKFLCFJD_01470 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GKFLCFJD_01471 2.8e-81 ykvN - - K - - - Transcriptional regulator
GKFLCFJD_01472 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GKFLCFJD_01473 2.69e-275 - - - M - - - Glycosyl transferases group 1
GKFLCFJD_01474 1.85e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
GKFLCFJD_01475 2.5e-169 - - - G - - - Glycosyl hydrolases family 18
GKFLCFJD_01476 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
GKFLCFJD_01477 5.43e-35 ykvS - - S - - - protein conserved in bacteria
GKFLCFJD_01478 2.6e-39 - - - - - - - -
GKFLCFJD_01479 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
GKFLCFJD_01480 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKFLCFJD_01481 5.79e-117 stoA - - CO - - - thiol-disulfide
GKFLCFJD_01482 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
GKFLCFJD_01483 3.99e-09 - - - - - - - -
GKFLCFJD_01484 7.85e-266 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
GKFLCFJD_01486 3.28e-230 ykvZ - - K - - - Transcriptional regulator
GKFLCFJD_01488 3.41e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
GKFLCFJD_01489 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_01490 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
GKFLCFJD_01491 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKFLCFJD_01492 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_01493 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
GKFLCFJD_01494 5.49e-170 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKFLCFJD_01495 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKFLCFJD_01496 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GKFLCFJD_01497 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
GKFLCFJD_01498 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKFLCFJD_01499 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_01500 5.32e-286 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKFLCFJD_01501 1.05e-22 - - - - - - - -
GKFLCFJD_01502 4.24e-217 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
GKFLCFJD_01503 3.71e-110 ykyB - - S - - - YkyB-like protein
GKFLCFJD_01504 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_01505 7.1e-116 ykuD - - S - - - protein conserved in bacteria
GKFLCFJD_01506 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
GKFLCFJD_01507 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_01508 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
GKFLCFJD_01509 1.52e-120 - - - M - - - Peptidoglycan-binding domain 1 protein
GKFLCFJD_01511 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
GKFLCFJD_01512 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
GKFLCFJD_01513 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
GKFLCFJD_01514 7.83e-38 ykzF - - S - - - Antirepressor AbbA
GKFLCFJD_01515 5.15e-100 ykuL - - S - - - CBS domain
GKFLCFJD_01516 6.52e-216 ccpC - - K - - - Transcriptional regulator
GKFLCFJD_01517 7.72e-114 - - - C ko:K03839 - ko00000 Flavodoxin domain
GKFLCFJD_01518 1.33e-226 ykuO - - - - - - -
GKFLCFJD_01519 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
GKFLCFJD_01520 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GKFLCFJD_01521 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GKFLCFJD_01522 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
GKFLCFJD_01523 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
GKFLCFJD_01524 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
GKFLCFJD_01525 6.25e-106 ykuV - - CO - - - thiol-disulfide
GKFLCFJD_01526 4.71e-122 rok - - K - - - Repressor of ComK
GKFLCFJD_01527 1.47e-201 yknT - - - ko:K06437 - ko00000 -
GKFLCFJD_01528 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GKFLCFJD_01529 6.5e-246 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GKFLCFJD_01530 1.05e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
GKFLCFJD_01531 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
GKFLCFJD_01532 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
GKFLCFJD_01533 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GKFLCFJD_01534 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKFLCFJD_01535 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKFLCFJD_01536 1.6e-151 yknW - - S - - - Yip1 domain
GKFLCFJD_01537 4.93e-235 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKFLCFJD_01538 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_01539 2.1e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GKFLCFJD_01540 1.49e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_01541 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
GKFLCFJD_01542 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GKFLCFJD_01543 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKFLCFJD_01544 5.43e-52 ykoA - - - - - - -
GKFLCFJD_01545 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GKFLCFJD_01546 2.99e-217 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKFLCFJD_01547 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
GKFLCFJD_01548 1.09e-18 - - - S - - - Uncharacterized protein YkpC
GKFLCFJD_01549 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
GKFLCFJD_01550 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
GKFLCFJD_01551 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GKFLCFJD_01552 9.21e-208 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
GKFLCFJD_01553 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
GKFLCFJD_01554 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GKFLCFJD_01555 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKFLCFJD_01556 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
GKFLCFJD_01557 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
GKFLCFJD_01558 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKFLCFJD_01559 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
GKFLCFJD_01560 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
GKFLCFJD_01561 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GKFLCFJD_01562 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GKFLCFJD_01563 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKFLCFJD_01564 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GKFLCFJD_01565 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
GKFLCFJD_01566 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
GKFLCFJD_01567 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
GKFLCFJD_01568 1.3e-152 yktB - - S - - - Belongs to the UPF0637 family
GKFLCFJD_01569 4.48e-35 ykzI - - - - - - -
GKFLCFJD_01570 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
GKFLCFJD_01571 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
GKFLCFJD_01572 1.28e-223 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GKFLCFJD_01573 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
GKFLCFJD_01574 0.0 ylaA - - - - - - -
GKFLCFJD_01575 1.44e-56 ylaB - - - - - - -
GKFLCFJD_01576 4.51e-118 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_01578 1.74e-57 ylaE - - - - - - -
GKFLCFJD_01579 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
GKFLCFJD_01580 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GKFLCFJD_01581 4.4e-63 ylaH - - S - - - YlaH-like protein
GKFLCFJD_01582 8.92e-44 ylaI - - S - - - protein conserved in bacteria
GKFLCFJD_01583 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GKFLCFJD_01584 5.64e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
GKFLCFJD_01585 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GKFLCFJD_01586 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GKFLCFJD_01587 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
GKFLCFJD_01588 2.57e-273 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GKFLCFJD_01589 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GKFLCFJD_01590 2.97e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
GKFLCFJD_01591 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GKFLCFJD_01592 5.85e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
GKFLCFJD_01593 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GKFLCFJD_01594 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
GKFLCFJD_01595 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
GKFLCFJD_01596 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
GKFLCFJD_01597 1.61e-81 ylbA - - S - - - YugN-like family
GKFLCFJD_01598 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
GKFLCFJD_01599 4.58e-258 ylbC - - S - - - protein with SCP PR1 domains
GKFLCFJD_01600 3.24e-89 ylbD - - S - - - Putative coat protein
GKFLCFJD_01601 1.73e-48 ylbE - - S - - - YlbE-like protein
GKFLCFJD_01602 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
GKFLCFJD_01603 4.36e-52 ylbG - - S - - - UPF0298 protein
GKFLCFJD_01604 2.12e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
GKFLCFJD_01605 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKFLCFJD_01606 2.73e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
GKFLCFJD_01607 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
GKFLCFJD_01608 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GKFLCFJD_01609 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
GKFLCFJD_01611 1.7e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
GKFLCFJD_01612 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GKFLCFJD_01613 5.75e-108 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
GKFLCFJD_01614 3.26e-116 ylbP - - K - - - n-acetyltransferase
GKFLCFJD_01615 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKFLCFJD_01616 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GKFLCFJD_01617 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GKFLCFJD_01618 4.97e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKFLCFJD_01619 3.42e-68 ftsL - - D - - - Essential cell division protein
GKFLCFJD_01620 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKFLCFJD_01621 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
GKFLCFJD_01622 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKFLCFJD_01623 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKFLCFJD_01624 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKFLCFJD_01625 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GKFLCFJD_01626 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKFLCFJD_01627 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
GKFLCFJD_01628 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKFLCFJD_01629 3.45e-146 ylxW - - S - - - protein conserved in bacteria
GKFLCFJD_01630 1.06e-132 ylxX - - S - - - protein conserved in bacteria
GKFLCFJD_01631 5.37e-76 sbp - - S - - - small basic protein
GKFLCFJD_01632 8.45e-300 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKFLCFJD_01633 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKFLCFJD_01634 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
GKFLCFJD_01635 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
GKFLCFJD_01636 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKFLCFJD_01637 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKFLCFJD_01638 3.84e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
GKFLCFJD_01639 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
GKFLCFJD_01640 3.58e-51 ylmC - - S - - - sporulation protein
GKFLCFJD_01641 5.53e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
GKFLCFJD_01642 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GKFLCFJD_01643 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GKFLCFJD_01644 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
GKFLCFJD_01645 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
GKFLCFJD_01646 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
GKFLCFJD_01647 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKFLCFJD_01648 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
GKFLCFJD_01649 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKFLCFJD_01650 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKFLCFJD_01651 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKFLCFJD_01652 2.24e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
GKFLCFJD_01653 4.4e-215 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GKFLCFJD_01654 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKFLCFJD_01655 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKFLCFJD_01656 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
GKFLCFJD_01657 3.84e-185 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GKFLCFJD_01658 1.33e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKFLCFJD_01659 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKFLCFJD_01660 3.8e-150 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKFLCFJD_01662 3.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
GKFLCFJD_01663 7.32e-230 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
GKFLCFJD_01664 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
GKFLCFJD_01665 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
GKFLCFJD_01666 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
GKFLCFJD_01667 4.33e-189 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
GKFLCFJD_01668 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
GKFLCFJD_01669 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
GKFLCFJD_01670 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
GKFLCFJD_01671 8.41e-202 yloC - - S - - - stress-induced protein
GKFLCFJD_01672 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
GKFLCFJD_01673 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GKFLCFJD_01674 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GKFLCFJD_01675 4.59e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKFLCFJD_01676 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKFLCFJD_01677 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKFLCFJD_01678 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKFLCFJD_01679 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKFLCFJD_01680 3.73e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GKFLCFJD_01681 3.03e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GKFLCFJD_01682 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GKFLCFJD_01683 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKFLCFJD_01684 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GKFLCFJD_01685 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GKFLCFJD_01686 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GKFLCFJD_01687 3.65e-78 yloU - - S - - - protein conserved in bacteria
GKFLCFJD_01688 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
GKFLCFJD_01689 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GKFLCFJD_01690 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GKFLCFJD_01691 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKFLCFJD_01692 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
GKFLCFJD_01693 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKFLCFJD_01694 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
GKFLCFJD_01695 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GKFLCFJD_01696 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKFLCFJD_01697 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKFLCFJD_01698 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GKFLCFJD_01699 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKFLCFJD_01700 1.67e-114 - - - - - - - -
GKFLCFJD_01701 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKFLCFJD_01702 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKFLCFJD_01703 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GKFLCFJD_01704 2.95e-50 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
GKFLCFJD_01705 5.89e-81 ylqD - - S - - - YlqD protein
GKFLCFJD_01706 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKFLCFJD_01707 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GKFLCFJD_01708 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKFLCFJD_01709 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKFLCFJD_01710 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKFLCFJD_01711 0.0 ylqG - - - - - - -
GKFLCFJD_01712 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
GKFLCFJD_01713 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GKFLCFJD_01714 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GKFLCFJD_01715 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
GKFLCFJD_01716 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKFLCFJD_01717 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GKFLCFJD_01718 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
GKFLCFJD_01719 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GKFLCFJD_01720 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GKFLCFJD_01721 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GKFLCFJD_01722 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
GKFLCFJD_01723 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
GKFLCFJD_01724 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
GKFLCFJD_01725 7.38e-35 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
GKFLCFJD_01726 1.66e-292 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
GKFLCFJD_01727 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GKFLCFJD_01728 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
GKFLCFJD_01729 2.11e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
GKFLCFJD_01730 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
GKFLCFJD_01731 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
GKFLCFJD_01732 2.31e-314 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
GKFLCFJD_01733 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
GKFLCFJD_01734 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
GKFLCFJD_01735 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
GKFLCFJD_01736 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GKFLCFJD_01737 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GKFLCFJD_01738 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
GKFLCFJD_01739 5.54e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
GKFLCFJD_01740 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
GKFLCFJD_01741 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
GKFLCFJD_01742 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
GKFLCFJD_01743 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GKFLCFJD_01744 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GKFLCFJD_01745 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
GKFLCFJD_01746 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
GKFLCFJD_01747 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
GKFLCFJD_01748 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
GKFLCFJD_01749 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
GKFLCFJD_01750 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
GKFLCFJD_01751 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
GKFLCFJD_01752 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKFLCFJD_01753 6.91e-101 ylxL - - - - - - -
GKFLCFJD_01754 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GKFLCFJD_01755 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKFLCFJD_01756 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GKFLCFJD_01757 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKFLCFJD_01758 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKFLCFJD_01759 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GKFLCFJD_01760 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GKFLCFJD_01761 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GKFLCFJD_01762 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKFLCFJD_01763 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKFLCFJD_01764 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GKFLCFJD_01765 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GKFLCFJD_01766 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
GKFLCFJD_01767 6.16e-63 ylxQ - - J - - - ribosomal protein
GKFLCFJD_01768 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKFLCFJD_01769 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
GKFLCFJD_01770 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKFLCFJD_01771 5.18e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKFLCFJD_01772 1.63e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GKFLCFJD_01773 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKFLCFJD_01774 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GKFLCFJD_01775 1.29e-235 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
GKFLCFJD_01776 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
GKFLCFJD_01777 1.53e-56 ymxH - - S - - - YlmC YmxH family
GKFLCFJD_01778 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
GKFLCFJD_01779 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GKFLCFJD_01780 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKFLCFJD_01781 1.2e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKFLCFJD_01782 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKFLCFJD_01783 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKFLCFJD_01784 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
GKFLCFJD_01785 4.94e-44 - - - S - - - YlzJ-like protein
GKFLCFJD_01786 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GKFLCFJD_01787 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_01788 2.08e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_01789 2.96e-302 albE - - S - - - Peptidase M16
GKFLCFJD_01790 2.37e-309 ymfH - - S - - - zinc protease
GKFLCFJD_01791 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
GKFLCFJD_01792 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
GKFLCFJD_01793 4.57e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
GKFLCFJD_01794 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
GKFLCFJD_01795 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKFLCFJD_01796 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GKFLCFJD_01797 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKFLCFJD_01798 8.43e-282 pbpX - - V - - - Beta-lactamase
GKFLCFJD_01799 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GKFLCFJD_01800 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
GKFLCFJD_01801 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
GKFLCFJD_01802 3.02e-255 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
GKFLCFJD_01803 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GKFLCFJD_01804 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GKFLCFJD_01805 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
GKFLCFJD_01806 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
GKFLCFJD_01807 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKFLCFJD_01808 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKFLCFJD_01809 7.19e-93 - - - S - - - Regulatory protein YrvL
GKFLCFJD_01811 1.38e-127 ymcC - - S - - - Membrane
GKFLCFJD_01812 2.94e-141 pksA - - K - - - Transcriptional regulator
GKFLCFJD_01813 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
GKFLCFJD_01814 1.31e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
GKFLCFJD_01816 2.08e-239 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
GKFLCFJD_01817 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
GKFLCFJD_01818 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
GKFLCFJD_01819 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GKFLCFJD_01820 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
GKFLCFJD_01821 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
GKFLCFJD_01822 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
GKFLCFJD_01823 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GKFLCFJD_01824 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
GKFLCFJD_01825 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GKFLCFJD_01826 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GKFLCFJD_01827 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
GKFLCFJD_01828 2.49e-297 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKFLCFJD_01829 2.8e-81 ymzB - - - - - - -
GKFLCFJD_01830 4.8e-210 - - - S - - - Metallo-beta-lactamase superfamily
GKFLCFJD_01831 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
GKFLCFJD_01832 3.96e-163 ymaC - - S - - - Replication protein
GKFLCFJD_01833 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
GKFLCFJD_01834 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
GKFLCFJD_01835 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
GKFLCFJD_01837 5.41e-76 ymaF - - S - - - YmaF family
GKFLCFJD_01838 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKFLCFJD_01839 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
GKFLCFJD_01840 8.07e-32 - - - - - - - -
GKFLCFJD_01841 1.2e-30 ymzA - - - - - - -
GKFLCFJD_01842 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
GKFLCFJD_01843 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKFLCFJD_01844 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKFLCFJD_01845 2.24e-141 - - - - - - - -
GKFLCFJD_01846 1.72e-151 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GKFLCFJD_01847 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
GKFLCFJD_01848 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKFLCFJD_01849 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
GKFLCFJD_01850 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
GKFLCFJD_01851 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GKFLCFJD_01852 2.95e-14 - - - - - - - -
GKFLCFJD_01853 2.61e-40 - - - - - - - -
GKFLCFJD_01854 7.13e-52 - - - - - - - -
GKFLCFJD_01855 5.4e-105 - - - G - - - regulation of fungal-type cell wall biogenesis
GKFLCFJD_01856 1.97e-186 ynaC - - - - - - -
GKFLCFJD_01857 7.56e-129 ynaD - - J - - - Acetyltransferase (GNAT) domain
GKFLCFJD_01858 1.65e-160 - - - S - - - Domain of unknown function (DUF3885)
GKFLCFJD_01859 1.06e-80 ynaF - - - - - - -
GKFLCFJD_01862 4.32e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
GKFLCFJD_01863 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
GKFLCFJD_01864 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
GKFLCFJD_01865 3.15e-278 xylR - - GK - - - ROK family
GKFLCFJD_01866 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
GKFLCFJD_01867 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
GKFLCFJD_01868 9.1e-148 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
GKFLCFJD_01869 3.64e-313 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKFLCFJD_01870 3.05e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKFLCFJD_01871 3.44e-110 - - - S - - - Protein of unknown function (DUF2691)
GKFLCFJD_01872 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
GKFLCFJD_01873 7.54e-22 - - - - - - - -
GKFLCFJD_01876 7.03e-213 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKFLCFJD_01878 1.55e-172 - - - S - - - Domain of unknown function, YrpD
GKFLCFJD_01881 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
GKFLCFJD_01882 8.92e-96 - - - - - - - -
GKFLCFJD_01883 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
GKFLCFJD_01886 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
GKFLCFJD_01887 2.38e-251 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
GKFLCFJD_01888 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
GKFLCFJD_01889 9.15e-199 yndG - - S - - - DoxX-like family
GKFLCFJD_01890 1.26e-151 - - - S - - - Domain of unknown function (DUF4166)
GKFLCFJD_01891 0.0 yndJ - - S - - - YndJ-like protein
GKFLCFJD_01893 1.68e-177 yndL - - S - - - Replication protein
GKFLCFJD_01894 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
GKFLCFJD_01895 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
GKFLCFJD_01897 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKFLCFJD_01898 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
GKFLCFJD_01899 3.97e-145 yneB - - L - - - resolvase
GKFLCFJD_01900 1.15e-43 ynzC - - S - - - UPF0291 protein
GKFLCFJD_01901 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GKFLCFJD_01902 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
GKFLCFJD_01903 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
GKFLCFJD_01904 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
GKFLCFJD_01905 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
GKFLCFJD_01906 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
GKFLCFJD_01907 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
GKFLCFJD_01908 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
GKFLCFJD_01909 1.21e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
GKFLCFJD_01910 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
GKFLCFJD_01911 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
GKFLCFJD_01912 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GKFLCFJD_01913 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GKFLCFJD_01914 9.26e-10 - - - S - - - Fur-regulated basic protein B
GKFLCFJD_01916 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
GKFLCFJD_01917 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
GKFLCFJD_01918 1.63e-71 yneQ - - - - - - -
GKFLCFJD_01919 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
GKFLCFJD_01920 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKFLCFJD_01921 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
GKFLCFJD_01922 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKFLCFJD_01923 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKFLCFJD_01924 1.82e-18 - - - - - - - -
GKFLCFJD_01925 1.06e-75 ynfC - - - - - - -
GKFLCFJD_01926 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
GKFLCFJD_01927 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
GKFLCFJD_01929 0.0 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
GKFLCFJD_01930 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
GKFLCFJD_01931 1.04e-104 yngA - - S - - - membrane
GKFLCFJD_01932 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GKFLCFJD_01933 2.01e-134 yngC - - S - - - membrane-associated protein
GKFLCFJD_01934 4.46e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
GKFLCFJD_01935 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GKFLCFJD_01936 1.48e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
GKFLCFJD_01937 7.02e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
GKFLCFJD_01938 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
GKFLCFJD_01939 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
GKFLCFJD_01940 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GKFLCFJD_01941 1.31e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
GKFLCFJD_01942 4.3e-41 - - - S - - - Family of unknown function (DUF5367)
GKFLCFJD_01944 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
GKFLCFJD_01945 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
GKFLCFJD_01946 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
GKFLCFJD_01947 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_01948 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_01949 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_01950 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_01951 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
GKFLCFJD_01952 2.54e-245 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GKFLCFJD_01953 9.8e-313 yoeA - - V - - - MATE efflux family protein
GKFLCFJD_01954 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
GKFLCFJD_01956 1.14e-124 - - - L - - - Integrase
GKFLCFJD_01957 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
GKFLCFJD_01958 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
GKFLCFJD_01959 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_01960 7.23e-238 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GKFLCFJD_01961 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GKFLCFJD_01962 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
GKFLCFJD_01963 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_01964 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKFLCFJD_01965 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKFLCFJD_01966 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
GKFLCFJD_01967 7.94e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_01968 8.39e-57 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
GKFLCFJD_01969 1.34e-185 yoxB - - - - - - -
GKFLCFJD_01970 5.91e-125 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GKFLCFJD_01971 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
GKFLCFJD_01972 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
GKFLCFJD_01973 3.41e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKFLCFJD_01974 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKFLCFJD_01975 2.08e-44 yoaF - - - - - - -
GKFLCFJD_01977 1.25e-20 - - - - - - - -
GKFLCFJD_01978 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
GKFLCFJD_01979 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
GKFLCFJD_01980 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
GKFLCFJD_01981 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
GKFLCFJD_01982 1.79e-145 yoaK - - S - - - Membrane
GKFLCFJD_01983 1.5e-254 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
GKFLCFJD_01984 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
GKFLCFJD_01986 1.95e-296 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
GKFLCFJD_01988 4.7e-188 yoaP - - K - - - YoaP-like
GKFLCFJD_01989 7.38e-88 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
GKFLCFJD_01990 2.36e-116 - - - - - - - -
GKFLCFJD_01991 3.63e-218 yoaR - - V - - - vancomycin resistance protein
GKFLCFJD_01992 1.6e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
GKFLCFJD_01993 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_01994 6.92e-192 yoaT - - S - - - Protein of unknown function (DUF817)
GKFLCFJD_01995 6.67e-203 yoaU - - K - - - LysR substrate binding domain
GKFLCFJD_01996 1.11e-202 yoaV - - EG - - - EamA-like transporter family
GKFLCFJD_01997 6.84e-103 yoaW - - - - - - -
GKFLCFJD_01998 3.88e-153 lin0465 - - S - - - DJ-1/PfpI family
GKFLCFJD_01999 9.26e-218 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
GKFLCFJD_02003 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
GKFLCFJD_02004 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
GKFLCFJD_02005 6.27e-51 - - - S - - - TM2 domain
GKFLCFJD_02006 3.92e-76 - - - K - - - Helix-turn-helix
GKFLCFJD_02008 1.21e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
GKFLCFJD_02009 1.92e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
GKFLCFJD_02010 6.85e-229 - - - - - - - -
GKFLCFJD_02011 1.36e-08 - - - - - - - -
GKFLCFJD_02015 6.23e-267 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
GKFLCFJD_02017 6.17e-158 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKFLCFJD_02018 1.52e-79 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKFLCFJD_02019 2.05e-51 - - - S - - - YolD-like protein
GKFLCFJD_02020 2.08e-64 - - - - - - - -
GKFLCFJD_02021 0.0 - - - K - - - Psort location Cytoplasmic, score
GKFLCFJD_02022 3.58e-202 - - - - - - - -
GKFLCFJD_02023 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
GKFLCFJD_02024 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GKFLCFJD_02025 4.3e-136 yokH - - G - - - SMI1 / KNR4 family
GKFLCFJD_02026 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
GKFLCFJD_02027 0.0 yobO - - M - - - Pectate lyase superfamily protein
GKFLCFJD_02028 2.21e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
GKFLCFJD_02029 5.23e-175 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
GKFLCFJD_02030 1.29e-183 - - - J - - - FR47-like protein
GKFLCFJD_02031 9.22e-129 yobS - - K - - - Transcriptional regulator
GKFLCFJD_02032 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GKFLCFJD_02033 1.55e-114 - - - K - - - Bacterial transcription activator, effector binding domain
GKFLCFJD_02034 2.05e-229 yobV - - K - - - WYL domain
GKFLCFJD_02035 7.69e-123 yobW - - - - - - -
GKFLCFJD_02036 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
GKFLCFJD_02037 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GKFLCFJD_02038 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
GKFLCFJD_02039 4.49e-186 - - - - - - - -
GKFLCFJD_02040 1.32e-122 yocC - - - - - - -
GKFLCFJD_02041 1.21e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
GKFLCFJD_02042 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
GKFLCFJD_02043 1.22e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_02044 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKFLCFJD_02045 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
GKFLCFJD_02046 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKFLCFJD_02047 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GKFLCFJD_02048 1.42e-107 yocK - - T - - - general stress protein
GKFLCFJD_02049 3.02e-70 yocL - - - - - - -
GKFLCFJD_02050 7.29e-46 - - - - - - - -
GKFLCFJD_02051 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKFLCFJD_02052 2.94e-55 yozN - - - - - - -
GKFLCFJD_02053 1.83e-49 yocN - - - - - - -
GKFLCFJD_02054 2.17e-74 yozO - - S - - - Bacterial PH domain
GKFLCFJD_02055 1.91e-42 yozC - - - - - - -
GKFLCFJD_02056 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKFLCFJD_02057 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
GKFLCFJD_02058 3.35e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
GKFLCFJD_02059 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GKFLCFJD_02060 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
GKFLCFJD_02061 3.16e-265 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
GKFLCFJD_02062 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GKFLCFJD_02063 0.0 yojO - - P - - - Von Willebrand factor
GKFLCFJD_02064 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
GKFLCFJD_02065 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GKFLCFJD_02066 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GKFLCFJD_02067 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
GKFLCFJD_02068 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKFLCFJD_02070 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
GKFLCFJD_02071 2.49e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKFLCFJD_02072 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
GKFLCFJD_02073 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
GKFLCFJD_02074 1.85e-58 - - - - - - - -
GKFLCFJD_02075 1.21e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
GKFLCFJD_02076 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
GKFLCFJD_02077 1.95e-14 - - - - - - - -
GKFLCFJD_02078 1.01e-293 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
GKFLCFJD_02079 2.05e-86 iolK - - S - - - tautomerase
GKFLCFJD_02080 1.37e-76 yodB - - K - - - transcriptional
GKFLCFJD_02081 1.92e-140 yodC - - C - - - nitroreductase
GKFLCFJD_02082 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
GKFLCFJD_02083 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GKFLCFJD_02084 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
GKFLCFJD_02085 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKFLCFJD_02086 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
GKFLCFJD_02087 6.38e-168 yodH - - Q - - - Methyltransferase
GKFLCFJD_02088 2.93e-42 yodI - - - - - - -
GKFLCFJD_02089 1.62e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
GKFLCFJD_02090 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
GKFLCFJD_02091 2.08e-12 - - - - - - - -
GKFLCFJD_02092 1.17e-71 yodL - - S - - - YodL-like
GKFLCFJD_02093 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
GKFLCFJD_02094 5.18e-34 yozD - - S - - - YozD-like protein
GKFLCFJD_02096 3.84e-161 yodN - - - - - - -
GKFLCFJD_02097 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
GKFLCFJD_02098 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
GKFLCFJD_02099 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
GKFLCFJD_02100 9.5e-200 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
GKFLCFJD_02101 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
GKFLCFJD_02102 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GKFLCFJD_02104 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKFLCFJD_02107 2.06e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
GKFLCFJD_02108 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
GKFLCFJD_02109 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
GKFLCFJD_02110 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
GKFLCFJD_02111 2.95e-240 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
GKFLCFJD_02112 4.17e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
GKFLCFJD_02113 1.13e-82 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
GKFLCFJD_02115 1.31e-139 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKFLCFJD_02124 6.52e-216 - - - S - - - Calcineurin-like phosphoesterase
GKFLCFJD_02125 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
GKFLCFJD_02130 2.85e-107 - - - L - - - Bacterial transcription activator, effector binding domain
GKFLCFJD_02131 3.02e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
GKFLCFJD_02132 2.34e-51 - - - O - - - Glutaredoxin
GKFLCFJD_02133 1.12e-87 - - - S - - - Ribonucleotide reductase, small chain
GKFLCFJD_02134 3.73e-126 - - - L - - - HNH endonuclease
GKFLCFJD_02135 1.59e-139 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKFLCFJD_02136 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKFLCFJD_02137 1.71e-160 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKFLCFJD_02138 7.75e-87 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
GKFLCFJD_02155 0.0 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
GKFLCFJD_02157 1.71e-126 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GKFLCFJD_02158 3.92e-115 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
GKFLCFJD_02163 9.54e-147 - - - S - - - protein conserved in bacteria
GKFLCFJD_02164 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GKFLCFJD_02165 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GKFLCFJD_02166 3.45e-288 - - - L - - - DNA primase activity
GKFLCFJD_02167 0.0 - - - J - - - DnaB-like helicase C terminal domain
GKFLCFJD_02168 1.1e-112 - - - - - - - -
GKFLCFJD_02169 6.35e-229 - - - L - - - AAA domain
GKFLCFJD_02170 2.37e-219 - - - - - - - -
GKFLCFJD_02175 0.0 - - - M - - - Parallel beta-helix repeats
GKFLCFJD_02176 1.83e-192 - - - S - - - Pfam:DUF867
GKFLCFJD_02179 2.62e-167 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
GKFLCFJD_02180 3.73e-199 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
GKFLCFJD_02181 6.17e-103 - - - - - - - -
GKFLCFJD_02188 3.88e-60 - - - - - - - -
GKFLCFJD_02190 9.17e-126 - - - S - - - Protein of unknown function (DUF1273)
GKFLCFJD_02192 1.16e-102 yoqH - - M - - - LysM domain
GKFLCFJD_02195 2.65e-15 - - - S - - - Protein of unknown function (DUF2815)
GKFLCFJD_02196 2.12e-175 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
GKFLCFJD_02202 0.000573 - - - S - - - YopX protein
GKFLCFJD_02207 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_02208 2.89e-226 - - - - - - - -
GKFLCFJD_02209 0.0 - - - S - - - DNA-sulfur modification-associated
GKFLCFJD_02210 2.04e-254 - - - L - - - Belongs to the 'phage' integrase family
GKFLCFJD_02215 7.95e-135 - - - - - - - -
GKFLCFJD_02217 8.39e-125 - - - - - - - -
GKFLCFJD_02218 2.68e-124 - - - S - - - Super-infection exclusion protein B
GKFLCFJD_02224 0.0 - - - - - - - -
GKFLCFJD_02225 7.56e-48 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
GKFLCFJD_02226 0.0 - - - - - - - -
GKFLCFJD_02228 1.07e-305 - - - - - - - -
GKFLCFJD_02231 6.64e-73 bldD - - K ko:K07110,ko:K21572 - ko00000,ko02000,ko03000 domain, Protein
GKFLCFJD_02234 0.0 - - - - - - - -
GKFLCFJD_02235 7.27e-56 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKFLCFJD_02237 2.29e-293 - - - - - - - -
GKFLCFJD_02240 4.45e-225 - - - - - - - -
GKFLCFJD_02241 0.0 - - - S - - - Terminase-like family
GKFLCFJD_02242 0.0 - - - - - - - -
GKFLCFJD_02243 0.0 - - - - - - - -
GKFLCFJD_02244 1.24e-122 - - - - - - - -
GKFLCFJD_02245 5.93e-237 - - - - - - - -
GKFLCFJD_02246 8.05e-106 - - - - - - - -
GKFLCFJD_02247 8.95e-91 - - - - - - - -
GKFLCFJD_02249 9.48e-157 - - - - - - - -
GKFLCFJD_02250 4.38e-118 - - - - - - - -
GKFLCFJD_02251 2.4e-169 - - - - - - - -
GKFLCFJD_02252 1.58e-145 - - - - - - - -
GKFLCFJD_02255 2.22e-76 - - - - - - - -
GKFLCFJD_02256 4.46e-229 - - - - - - - -
GKFLCFJD_02259 1.65e-112 - - - - - - - -
GKFLCFJD_02260 2e-94 - - - - - - - -
GKFLCFJD_02261 1.73e-247 - - - A - - - Belongs to the 'phage' integrase family
GKFLCFJD_02266 5.66e-159 - - - - - - - -
GKFLCFJD_02267 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GKFLCFJD_02268 1.7e-186 - - - S - - - Phage tail protein
GKFLCFJD_02269 0.0 - - - S - - - Pfam Transposase IS66
GKFLCFJD_02270 9.28e-166 - - - - - - - -
GKFLCFJD_02271 0.0 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
GKFLCFJD_02272 1.31e-210 - - - - - - - -
GKFLCFJD_02274 7.44e-257 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
GKFLCFJD_02275 1.42e-43 bhlA - - S - - - BhlA holin family
GKFLCFJD_02276 3.04e-53 - - - S - - - SPP1 phage holin
GKFLCFJD_02277 5.12e-96 - - - O ko:K03611 - ko00000,ko03110 protein disulfide oxidoreductase activity
GKFLCFJD_02278 6.04e-309 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
GKFLCFJD_02279 3.44e-91 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 cell redox homeostasis
GKFLCFJD_02280 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 Peptidase C39 family
GKFLCFJD_02283 2.97e-306 - - - S - - - damaged DNA binding
GKFLCFJD_02284 7.69e-73 - - - S - - - YolD-like protein
GKFLCFJD_02285 7.43e-49 - - - - - - - -
GKFLCFJD_02289 5.26e-128 - - - J - - - Acetyltransferase (GNAT) domain
GKFLCFJD_02290 5.38e-142 yokK - - S - - - SMI1 / KNR4 family
GKFLCFJD_02291 9.26e-123 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
GKFLCFJD_02292 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
GKFLCFJD_02293 2.64e-119 yokH - - G - - - SMI1 / KNR4 family
GKFLCFJD_02294 5.27e-261 - - - - - - - -
GKFLCFJD_02295 2.55e-178 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
GKFLCFJD_02296 6.83e-109 - - - S - - - Bacterial PH domain
GKFLCFJD_02297 8.79e-199 yokD 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 aminoglycoside
GKFLCFJD_02300 5.1e-123 - - - - - - - -
GKFLCFJD_02301 4.93e-153 - - - - - - - -
GKFLCFJD_02302 0.0 yokA - - L - - - Recombinase
GKFLCFJD_02303 1.76e-124 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
GKFLCFJD_02304 3.52e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GKFLCFJD_02305 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKFLCFJD_02306 4.14e-94 ypoP - - K - - - transcriptional
GKFLCFJD_02307 3.49e-290 mepA - - V - - - MATE efflux family protein
GKFLCFJD_02308 2.13e-40 ypmT - - S - - - Uncharacterized ympT
GKFLCFJD_02309 6.8e-129 ypmS - - S - - - protein conserved in bacteria
GKFLCFJD_02310 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
GKFLCFJD_02311 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GKFLCFJD_02312 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
GKFLCFJD_02313 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GKFLCFJD_02314 1.4e-236 yplP - - K - - - Transcriptional regulator
GKFLCFJD_02315 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
GKFLCFJD_02316 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GKFLCFJD_02317 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKFLCFJD_02318 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKFLCFJD_02319 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
GKFLCFJD_02320 3.47e-148 ypjP - - S - - - YpjP-like protein
GKFLCFJD_02321 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
GKFLCFJD_02322 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
GKFLCFJD_02323 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
GKFLCFJD_02324 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
GKFLCFJD_02325 2.52e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
GKFLCFJD_02326 1.89e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
GKFLCFJD_02327 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GKFLCFJD_02328 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GKFLCFJD_02329 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
GKFLCFJD_02330 1.17e-22 degR - - - - - - -
GKFLCFJD_02331 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
GKFLCFJD_02332 1.54e-37 ypeQ - - S - - - Zinc-finger
GKFLCFJD_02333 4e-163 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
GKFLCFJD_02334 2.4e-138 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GKFLCFJD_02335 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
GKFLCFJD_02336 5.23e-05 - - - - ko:K06429 - ko00000 -
GKFLCFJD_02337 2.26e-213 ypcP - - L - - - 5'3' exonuclease
GKFLCFJD_02338 1.08e-11 - - - - - - - -
GKFLCFJD_02339 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
GKFLCFJD_02340 0.0 ypbR - - S - - - Dynamin family
GKFLCFJD_02341 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
GKFLCFJD_02342 4.55e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
GKFLCFJD_02343 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
GKFLCFJD_02344 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKFLCFJD_02345 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GKFLCFJD_02346 1e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
GKFLCFJD_02347 2.53e-133 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
GKFLCFJD_02348 6.95e-238 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
GKFLCFJD_02349 1.92e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
GKFLCFJD_02350 1.25e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GKFLCFJD_02351 2.05e-179 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_02352 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
GKFLCFJD_02354 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GKFLCFJD_02355 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKFLCFJD_02356 3.41e-130 ypsA - - S - - - Belongs to the UPF0398 family
GKFLCFJD_02357 7.21e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
GKFLCFJD_02358 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
GKFLCFJD_02359 2.34e-113 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
GKFLCFJD_02360 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKFLCFJD_02361 8.72e-68 yppG - - S - - - YppG-like protein
GKFLCFJD_02362 9.21e-11 - - - S - - - YppF-like protein
GKFLCFJD_02363 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
GKFLCFJD_02366 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
GKFLCFJD_02367 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKFLCFJD_02368 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKFLCFJD_02369 1.43e-121 ypoC - - - - - - -
GKFLCFJD_02370 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKFLCFJD_02371 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
GKFLCFJD_02372 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
GKFLCFJD_02373 1.07e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GKFLCFJD_02374 2.27e-103 ypmB - - S - - - protein conserved in bacteria
GKFLCFJD_02375 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
GKFLCFJD_02376 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GKFLCFJD_02377 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GKFLCFJD_02378 1.34e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GKFLCFJD_02379 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
GKFLCFJD_02380 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GKFLCFJD_02381 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKFLCFJD_02382 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
GKFLCFJD_02383 6.61e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
GKFLCFJD_02384 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
GKFLCFJD_02385 8.38e-190 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GKFLCFJD_02386 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
GKFLCFJD_02387 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKFLCFJD_02388 6.84e-183 ypjB - - S - - - sporulation protein
GKFLCFJD_02389 1.63e-125 ypjA - - S - - - membrane
GKFLCFJD_02390 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
GKFLCFJD_02391 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
GKFLCFJD_02392 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
GKFLCFJD_02393 4.75e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
GKFLCFJD_02394 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
GKFLCFJD_02395 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
GKFLCFJD_02396 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GKFLCFJD_02397 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
GKFLCFJD_02398 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GKFLCFJD_02399 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GKFLCFJD_02400 9.33e-295 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GKFLCFJD_02401 2.82e-153 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
GKFLCFJD_02402 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
GKFLCFJD_02403 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GKFLCFJD_02404 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GKFLCFJD_02405 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
GKFLCFJD_02406 8.48e-265 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GKFLCFJD_02407 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GKFLCFJD_02408 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
GKFLCFJD_02409 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GKFLCFJD_02410 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKFLCFJD_02411 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GKFLCFJD_02412 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
GKFLCFJD_02413 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
GKFLCFJD_02414 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
GKFLCFJD_02415 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKFLCFJD_02416 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GKFLCFJD_02417 9.07e-178 yphF - - - - - - -
GKFLCFJD_02418 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
GKFLCFJD_02419 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GKFLCFJD_02420 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GKFLCFJD_02421 8.69e-40 ypzH - - - - - - -
GKFLCFJD_02422 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
GKFLCFJD_02423 2.73e-134 yphA - - - - - - -
GKFLCFJD_02424 1.13e-11 - - - S - - - YpzI-like protein
GKFLCFJD_02425 8.41e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKFLCFJD_02426 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GKFLCFJD_02427 1.73e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GKFLCFJD_02428 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
GKFLCFJD_02429 4.63e-144 ypfA - - M - - - Flagellar protein YcgR
GKFLCFJD_02430 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
GKFLCFJD_02431 4.88e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
GKFLCFJD_02432 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
GKFLCFJD_02433 1.62e-227 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
GKFLCFJD_02434 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GKFLCFJD_02435 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GKFLCFJD_02436 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
GKFLCFJD_02437 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
GKFLCFJD_02438 5.04e-148 ypbE - - M - - - Lysin motif
GKFLCFJD_02439 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
GKFLCFJD_02440 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKFLCFJD_02441 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
GKFLCFJD_02442 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
GKFLCFJD_02443 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKFLCFJD_02444 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKFLCFJD_02445 2.89e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GKFLCFJD_02446 2.7e-257 rsiX - - - - - - -
GKFLCFJD_02447 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_02448 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_02449 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_02450 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GKFLCFJD_02451 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
GKFLCFJD_02452 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
GKFLCFJD_02453 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKFLCFJD_02454 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
GKFLCFJD_02455 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
GKFLCFJD_02456 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKFLCFJD_02457 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
GKFLCFJD_02458 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKFLCFJD_02459 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKFLCFJD_02460 3.34e-93 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
GKFLCFJD_02461 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKFLCFJD_02462 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GKFLCFJD_02463 3.12e-292 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GKFLCFJD_02464 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GKFLCFJD_02465 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKFLCFJD_02466 2.96e-72 ypuD - - - - - - -
GKFLCFJD_02467 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKFLCFJD_02468 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
GKFLCFJD_02470 3.82e-09 - - - S - - - SNARE associated Golgi protein
GKFLCFJD_02472 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKFLCFJD_02473 2.67e-193 ypuA - - S - - - Secreted protein
GKFLCFJD_02474 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GKFLCFJD_02475 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
GKFLCFJD_02476 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
GKFLCFJD_02477 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
GKFLCFJD_02478 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
GKFLCFJD_02479 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
GKFLCFJD_02480 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
GKFLCFJD_02481 5.72e-144 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
GKFLCFJD_02482 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKFLCFJD_02483 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
GKFLCFJD_02484 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
GKFLCFJD_02485 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKFLCFJD_02486 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GKFLCFJD_02487 2.89e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GKFLCFJD_02488 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
GKFLCFJD_02489 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
GKFLCFJD_02490 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
GKFLCFJD_02491 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
GKFLCFJD_02492 3.73e-44 yqkK - - - - - - -
GKFLCFJD_02493 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
GKFLCFJD_02494 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
GKFLCFJD_02495 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
GKFLCFJD_02496 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
GKFLCFJD_02497 3.18e-77 ansR - - K - - - Transcriptional regulator
GKFLCFJD_02498 2.62e-283 yqxK - - L - - - DNA helicase
GKFLCFJD_02499 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
GKFLCFJD_02500 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
GKFLCFJD_02501 9.26e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
GKFLCFJD_02502 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
GKFLCFJD_02503 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
GKFLCFJD_02504 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
GKFLCFJD_02505 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
GKFLCFJD_02506 2.89e-251 yqkA - - K - - - GrpB protein
GKFLCFJD_02507 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
GKFLCFJD_02508 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
GKFLCFJD_02509 1.87e-65 yqiX - - S - - - YolD-like protein
GKFLCFJD_02510 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKFLCFJD_02512 1.08e-289 yqjV - - G - - - Major Facilitator Superfamily
GKFLCFJD_02514 1.33e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKFLCFJD_02515 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GKFLCFJD_02516 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
GKFLCFJD_02517 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_02518 3.98e-230 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GKFLCFJD_02519 6.84e-190 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKFLCFJD_02520 0.0 rocB - - E - - - arginine degradation protein
GKFLCFJD_02521 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GKFLCFJD_02522 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GKFLCFJD_02523 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKFLCFJD_02524 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKFLCFJD_02525 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKFLCFJD_02526 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKFLCFJD_02527 1.77e-32 yqzJ - - - - - - -
GKFLCFJD_02528 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKFLCFJD_02529 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
GKFLCFJD_02530 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
GKFLCFJD_02531 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GKFLCFJD_02532 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
GKFLCFJD_02534 2.41e-128 yqjB - - S - - - protein conserved in bacteria
GKFLCFJD_02535 9.33e-226 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
GKFLCFJD_02536 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GKFLCFJD_02537 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GKFLCFJD_02538 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GKFLCFJD_02539 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
GKFLCFJD_02540 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GKFLCFJD_02541 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_02542 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
GKFLCFJD_02543 1.57e-296 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKFLCFJD_02544 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GKFLCFJD_02545 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GKFLCFJD_02546 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GKFLCFJD_02547 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
GKFLCFJD_02548 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GKFLCFJD_02549 6.35e-201 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
GKFLCFJD_02550 0.0 bkdR - - KT - - - Transcriptional regulator
GKFLCFJD_02551 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
GKFLCFJD_02552 1.07e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GKFLCFJD_02553 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
GKFLCFJD_02554 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GKFLCFJD_02555 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
GKFLCFJD_02556 7.2e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
GKFLCFJD_02557 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GKFLCFJD_02558 3.68e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GKFLCFJD_02559 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
GKFLCFJD_02560 2.26e-37 - - - - - - - -
GKFLCFJD_02561 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
GKFLCFJD_02563 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
GKFLCFJD_02564 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
GKFLCFJD_02565 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GKFLCFJD_02566 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GKFLCFJD_02567 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
GKFLCFJD_02568 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKFLCFJD_02569 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKFLCFJD_02570 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKFLCFJD_02571 2.5e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKFLCFJD_02572 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKFLCFJD_02573 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKFLCFJD_02574 1.65e-88 yqhY - - S - - - protein conserved in bacteria
GKFLCFJD_02575 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GKFLCFJD_02576 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GKFLCFJD_02577 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
GKFLCFJD_02578 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
GKFLCFJD_02579 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
GKFLCFJD_02580 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
GKFLCFJD_02581 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
GKFLCFJD_02582 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
GKFLCFJD_02583 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
GKFLCFJD_02584 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
GKFLCFJD_02585 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
GKFLCFJD_02586 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKFLCFJD_02587 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
GKFLCFJD_02588 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
GKFLCFJD_02589 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
GKFLCFJD_02590 3.79e-223 yqhQ - - S - - - Protein of unknown function (DUF1385)
GKFLCFJD_02591 5.18e-81 yqhP - - - - - - -
GKFLCFJD_02592 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
GKFLCFJD_02593 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
GKFLCFJD_02594 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
GKFLCFJD_02595 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
GKFLCFJD_02596 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKFLCFJD_02597 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKFLCFJD_02598 8.13e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
GKFLCFJD_02599 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
GKFLCFJD_02600 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
GKFLCFJD_02601 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
GKFLCFJD_02602 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
GKFLCFJD_02603 1.56e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
GKFLCFJD_02604 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
GKFLCFJD_02605 8.73e-160 yqxM - - - ko:K19433 - ko00000 -
GKFLCFJD_02606 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
GKFLCFJD_02607 4.9e-37 yqzE - - S - - - YqzE-like protein
GKFLCFJD_02608 2.55e-55 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
GKFLCFJD_02609 3.44e-65 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
GKFLCFJD_02610 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
GKFLCFJD_02611 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
GKFLCFJD_02612 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
GKFLCFJD_02613 1.29e-220 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
GKFLCFJD_02614 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GKFLCFJD_02616 1.51e-233 yqxL - - P - - - Mg2 transporter protein
GKFLCFJD_02617 8.56e-307 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GKFLCFJD_02618 1.06e-193 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKFLCFJD_02620 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
GKFLCFJD_02621 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
GKFLCFJD_02622 5.52e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
GKFLCFJD_02623 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
GKFLCFJD_02624 7.34e-66 yqgV - - S - - - Thiamine-binding protein
GKFLCFJD_02625 5.65e-258 yqgU - - - - - - -
GKFLCFJD_02626 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
GKFLCFJD_02627 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GKFLCFJD_02628 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GKFLCFJD_02629 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
GKFLCFJD_02630 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
GKFLCFJD_02631 3.38e-14 yqgO - - - - - - -
GKFLCFJD_02632 2.38e-138 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKFLCFJD_02633 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GKFLCFJD_02634 1.24e-260 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
GKFLCFJD_02636 3.42e-68 yqzD - - - - - - -
GKFLCFJD_02637 2.92e-98 yqzC - - S - - - YceG-like family
GKFLCFJD_02638 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKFLCFJD_02639 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKFLCFJD_02640 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
GKFLCFJD_02641 7.43e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GKFLCFJD_02642 4.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GKFLCFJD_02643 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
GKFLCFJD_02644 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
GKFLCFJD_02645 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
GKFLCFJD_02646 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
GKFLCFJD_02647 9.27e-172 yqgB - - S - - - Protein of unknown function (DUF1189)
GKFLCFJD_02648 2.05e-99 yqgA - - - - - - -
GKFLCFJD_02649 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
GKFLCFJD_02650 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GKFLCFJD_02651 2.04e-81 yqfX - - S - - - membrane
GKFLCFJD_02652 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
GKFLCFJD_02653 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
GKFLCFJD_02654 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKFLCFJD_02655 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
GKFLCFJD_02656 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GKFLCFJD_02657 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKFLCFJD_02658 4.89e-58 yqfQ - - S - - - YqfQ-like protein
GKFLCFJD_02659 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GKFLCFJD_02660 2.27e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKFLCFJD_02661 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GKFLCFJD_02662 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
GKFLCFJD_02663 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKFLCFJD_02664 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKFLCFJD_02665 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
GKFLCFJD_02666 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GKFLCFJD_02667 3.29e-144 ccpN - - K - - - CBS domain
GKFLCFJD_02668 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GKFLCFJD_02669 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GKFLCFJD_02670 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GKFLCFJD_02671 5.29e-27 - - - S - - - YqzL-like protein
GKFLCFJD_02672 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKFLCFJD_02673 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GKFLCFJD_02674 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GKFLCFJD_02675 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKFLCFJD_02676 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
GKFLCFJD_02678 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
GKFLCFJD_02679 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
GKFLCFJD_02680 2.07e-60 yqfC - - S - - - sporulation protein YqfC
GKFLCFJD_02681 3.13e-79 yqfB - - - - - - -
GKFLCFJD_02682 4.35e-192 yqfA - - S - - - UPF0365 protein
GKFLCFJD_02683 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
GKFLCFJD_02684 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
GKFLCFJD_02685 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GKFLCFJD_02686 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
GKFLCFJD_02687 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
GKFLCFJD_02688 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GKFLCFJD_02689 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
GKFLCFJD_02690 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKFLCFJD_02691 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GKFLCFJD_02692 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKFLCFJD_02693 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKFLCFJD_02694 4.3e-278 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
GKFLCFJD_02695 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKFLCFJD_02696 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
GKFLCFJD_02697 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
GKFLCFJD_02698 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GKFLCFJD_02699 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GKFLCFJD_02700 2.01e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GKFLCFJD_02701 2.36e-22 - - - S - - - YqzM-like protein
GKFLCFJD_02702 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GKFLCFJD_02703 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GKFLCFJD_02704 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
GKFLCFJD_02705 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKFLCFJD_02706 9.8e-179 yqeM - - Q - - - Methyltransferase
GKFLCFJD_02707 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKFLCFJD_02708 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
GKFLCFJD_02709 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKFLCFJD_02710 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
GKFLCFJD_02711 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKFLCFJD_02712 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GKFLCFJD_02713 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
GKFLCFJD_02715 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
GKFLCFJD_02716 7.45e-180 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
GKFLCFJD_02717 3.97e-136 yqeD - - S - - - SNARE associated Golgi protein
GKFLCFJD_02718 7.95e-219 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
GKFLCFJD_02719 9.38e-171 - - - - - - - -
GKFLCFJD_02720 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
GKFLCFJD_02721 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKFLCFJD_02722 0.0 - - - L ko:K06400 - ko00000 Recombinase
GKFLCFJD_02723 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
GKFLCFJD_02724 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
GKFLCFJD_02725 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKFLCFJD_02726 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
GKFLCFJD_02727 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
GKFLCFJD_02728 8.68e-120 - - - S - - - Tetratricopeptide repeat
GKFLCFJD_02731 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
GKFLCFJD_02732 1.66e-136 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
GKFLCFJD_02734 5.4e-80 - - - - - - - -
GKFLCFJD_02736 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
GKFLCFJD_02737 8.36e-89 - - - S - - - Bacteriophage holin family
GKFLCFJD_02738 2.45e-213 xepA - - - - - - -
GKFLCFJD_02739 9.34e-33 - - - - - - - -
GKFLCFJD_02740 1.01e-73 xkdW - - S - - - XkdW protein
GKFLCFJD_02741 2.91e-283 - - - - - - - -
GKFLCFJD_02742 3e-54 - - - - - - - -
GKFLCFJD_02743 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
GKFLCFJD_02744 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GKFLCFJD_02745 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
GKFLCFJD_02746 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
GKFLCFJD_02747 1.02e-231 xkdQ - - G - - - NLP P60 protein
GKFLCFJD_02748 6.56e-156 xkdP - - S - - - Lysin motif
GKFLCFJD_02749 0.0 xkdO - - L - - - Transglycosylase SLT domain
GKFLCFJD_02750 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
GKFLCFJD_02752 4.23e-99 xkdM - - S - - - Phage tail tube protein
GKFLCFJD_02753 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
GKFLCFJD_02754 2.52e-36 - - - - - - - -
GKFLCFJD_02755 3.24e-102 yqbJ - - - - - - -
GKFLCFJD_02756 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GKFLCFJD_02757 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
GKFLCFJD_02758 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
GKFLCFJD_02759 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
GKFLCFJD_02760 9.21e-216 xkdG - - S - - - Phage capsid family
GKFLCFJD_02761 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
GKFLCFJD_02762 2.13e-149 - - - - - - - -
GKFLCFJD_02763 1.73e-217 - - - S - - - Phage Mu protein F like protein
GKFLCFJD_02764 0.0 yqbA - - S - - - portal protein
GKFLCFJD_02765 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
GKFLCFJD_02766 2.02e-158 yqaS - - L - - - DNA packaging
GKFLCFJD_02768 1.58e-105 yqaQ - - L - - - Transposase
GKFLCFJD_02769 7.56e-214 - - - - - - - -
GKFLCFJD_02770 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
GKFLCFJD_02771 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
GKFLCFJD_02773 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
GKFLCFJD_02774 3.33e-159 yqaL - - L - - - DnaD domain protein
GKFLCFJD_02775 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
GKFLCFJD_02776 9.38e-229 yqaJ - - L - - - YqaJ-like viral recombinase domain
GKFLCFJD_02780 1.27e-134 - - - - - - - -
GKFLCFJD_02782 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
GKFLCFJD_02783 1.25e-74 - - - K - - - sequence-specific DNA binding
GKFLCFJD_02785 8.73e-132 yqaC - - F - - - adenylate kinase activity
GKFLCFJD_02786 2.25e-131 xkdA - - E - - - IrrE N-terminal-like domain
GKFLCFJD_02787 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKFLCFJD_02788 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
GKFLCFJD_02789 7.32e-306 yrkQ - - T - - - Histidine kinase
GKFLCFJD_02790 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
GKFLCFJD_02791 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
GKFLCFJD_02792 1.33e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
GKFLCFJD_02793 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
GKFLCFJD_02794 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
GKFLCFJD_02795 1.21e-170 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
GKFLCFJD_02796 1.11e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
GKFLCFJD_02797 2.1e-272 yrkH - - P - - - Rhodanese Homology Domain
GKFLCFJD_02798 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
GKFLCFJD_02799 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
GKFLCFJD_02800 4.38e-52 yrkD - - S - - - protein conserved in bacteria
GKFLCFJD_02801 3.81e-139 yrkC - - G - - - Cupin domain
GKFLCFJD_02802 2.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
GKFLCFJD_02803 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_02804 3.73e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
GKFLCFJD_02805 1.58e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GKFLCFJD_02806 7.28e-25 - - - S - - - YrzO-like protein
GKFLCFJD_02807 1.53e-219 yrdR - - EG - - - EamA-like transporter family
GKFLCFJD_02808 1.2e-204 - - - K - - - Transcriptional regulator
GKFLCFJD_02809 2.58e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
GKFLCFJD_02810 2.26e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
GKFLCFJD_02811 1.75e-87 yodA - - S - - - tautomerase
GKFLCFJD_02812 2.08e-209 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
GKFLCFJD_02814 2.22e-295 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GKFLCFJD_02815 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
GKFLCFJD_02816 2.29e-176 azlC - - E - - - AzlC protein
GKFLCFJD_02817 1.44e-104 bkdR - - K - - - helix_turn_helix ASNC type
GKFLCFJD_02818 1.07e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
GKFLCFJD_02819 1.75e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKFLCFJD_02821 7.37e-133 yrdC - - Q - - - Isochorismatase family
GKFLCFJD_02822 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
GKFLCFJD_02823 1.47e-120 yrdA - - S - - - DinB family
GKFLCFJD_02824 2.66e-215 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
GKFLCFJD_02825 3.79e-249 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
GKFLCFJD_02826 8.73e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GKFLCFJD_02827 5.87e-163 yrpD - - S - - - Domain of unknown function, YrpD
GKFLCFJD_02829 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
GKFLCFJD_02830 1.1e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_02831 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
GKFLCFJD_02832 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GKFLCFJD_02833 5.13e-211 yraN - - K - - - Transcriptional regulator
GKFLCFJD_02834 7.25e-264 yraM - - S - - - PrpF protein
GKFLCFJD_02836 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
GKFLCFJD_02837 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKFLCFJD_02838 4.9e-200 - - - S - - - Alpha beta hydrolase
GKFLCFJD_02839 6.61e-80 - - - T - - - sh3 domain protein
GKFLCFJD_02840 2.92e-81 - - - T - - - sh3 domain protein
GKFLCFJD_02841 6.62e-87 - - - E - - - Glyoxalase-like domain
GKFLCFJD_02842 4.19e-50 yraG - - - ko:K06440 - ko00000 -
GKFLCFJD_02843 9.61e-84 yraF - - M - - - Spore coat protein
GKFLCFJD_02844 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GKFLCFJD_02845 1.05e-36 yraE - - - ko:K06440 - ko00000 -
GKFLCFJD_02846 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
GKFLCFJD_02847 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
GKFLCFJD_02848 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
GKFLCFJD_02849 4.3e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
GKFLCFJD_02850 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
GKFLCFJD_02851 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
GKFLCFJD_02852 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
GKFLCFJD_02853 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
GKFLCFJD_02854 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
GKFLCFJD_02855 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
GKFLCFJD_02856 0.0 levR - - K - - - PTS system fructose IIA component
GKFLCFJD_02857 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GKFLCFJD_02858 5.63e-137 yrhP - - E - - - LysE type translocator
GKFLCFJD_02859 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
GKFLCFJD_02860 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_02861 3.67e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
GKFLCFJD_02862 0.0 oatA - - I - - - Acyltransferase family
GKFLCFJD_02863 2.67e-62 yrhK - - S - - - YrhK-like protein
GKFLCFJD_02864 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
GKFLCFJD_02865 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
GKFLCFJD_02866 1.1e-126 yrhH - - Q - - - methyltransferase
GKFLCFJD_02867 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
GKFLCFJD_02869 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
GKFLCFJD_02870 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
GKFLCFJD_02871 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
GKFLCFJD_02872 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
GKFLCFJD_02873 6.93e-49 yrhC - - S - - - YrhC-like protein
GKFLCFJD_02874 4.24e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GKFLCFJD_02875 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
GKFLCFJD_02876 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKFLCFJD_02877 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
GKFLCFJD_02878 7.27e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
GKFLCFJD_02879 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
GKFLCFJD_02880 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
GKFLCFJD_02881 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKFLCFJD_02882 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GKFLCFJD_02883 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
GKFLCFJD_02884 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
GKFLCFJD_02885 1.7e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
GKFLCFJD_02886 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKFLCFJD_02887 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
GKFLCFJD_02888 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKFLCFJD_02889 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
GKFLCFJD_02890 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKFLCFJD_02891 3.07e-242 yrrI - - S - - - AI-2E family transporter
GKFLCFJD_02892 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GKFLCFJD_02893 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GKFLCFJD_02894 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKFLCFJD_02895 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKFLCFJD_02896 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
GKFLCFJD_02897 8.4e-42 yrzR - - - - - - -
GKFLCFJD_02898 1.23e-108 yrrD - - S - - - protein conserved in bacteria
GKFLCFJD_02899 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKFLCFJD_02900 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
GKFLCFJD_02901 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKFLCFJD_02902 2.67e-272 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GKFLCFJD_02903 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_02904 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
GKFLCFJD_02905 3.4e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
GKFLCFJD_02906 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GKFLCFJD_02907 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GKFLCFJD_02909 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
GKFLCFJD_02910 1.6e-89 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKFLCFJD_02911 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKFLCFJD_02912 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKFLCFJD_02913 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GKFLCFJD_02914 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
GKFLCFJD_02915 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
GKFLCFJD_02916 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GKFLCFJD_02917 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
GKFLCFJD_02918 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKFLCFJD_02919 6.34e-147 yrbG - - S - - - membrane
GKFLCFJD_02920 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
GKFLCFJD_02921 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
GKFLCFJD_02922 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GKFLCFJD_02923 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GKFLCFJD_02924 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
GKFLCFJD_02925 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKFLCFJD_02926 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKFLCFJD_02927 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
GKFLCFJD_02928 0.0 csbX - - EGP - - - the major facilitator superfamily
GKFLCFJD_02929 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
GKFLCFJD_02930 2.32e-152 yrzF - - T - - - serine threonine protein kinase
GKFLCFJD_02932 2.42e-47 - - - S - - - Family of unknown function (DUF5412)
GKFLCFJD_02933 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
GKFLCFJD_02934 8.63e-165 yebC - - K - - - transcriptional regulatory protein
GKFLCFJD_02935 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GKFLCFJD_02936 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
GKFLCFJD_02937 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GKFLCFJD_02938 8.17e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
GKFLCFJD_02939 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
GKFLCFJD_02940 1.27e-294 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GKFLCFJD_02941 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
GKFLCFJD_02942 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
GKFLCFJD_02943 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
GKFLCFJD_02944 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKFLCFJD_02945 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
GKFLCFJD_02946 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GKFLCFJD_02947 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
GKFLCFJD_02948 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GKFLCFJD_02949 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
GKFLCFJD_02950 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
GKFLCFJD_02951 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
GKFLCFJD_02952 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GKFLCFJD_02953 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
GKFLCFJD_02954 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GKFLCFJD_02955 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
GKFLCFJD_02956 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
GKFLCFJD_02957 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
GKFLCFJD_02958 4.67e-215 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
GKFLCFJD_02959 3.15e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
GKFLCFJD_02960 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GKFLCFJD_02961 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKFLCFJD_02962 1.53e-35 - - - - - - - -
GKFLCFJD_02963 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GKFLCFJD_02964 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
GKFLCFJD_02965 8.99e-315 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
GKFLCFJD_02966 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
GKFLCFJD_02967 1.57e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
GKFLCFJD_02968 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GKFLCFJD_02969 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
GKFLCFJD_02970 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GKFLCFJD_02971 8.23e-117 ysxD - - - - - - -
GKFLCFJD_02972 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GKFLCFJD_02973 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GKFLCFJD_02974 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
GKFLCFJD_02975 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKFLCFJD_02976 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKFLCFJD_02977 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
GKFLCFJD_02978 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKFLCFJD_02979 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKFLCFJD_02980 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GKFLCFJD_02981 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKFLCFJD_02982 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GKFLCFJD_02983 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GKFLCFJD_02984 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GKFLCFJD_02986 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
GKFLCFJD_02987 1.01e-184 ysnF - - S - - - protein conserved in bacteria
GKFLCFJD_02989 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
GKFLCFJD_02990 1.06e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKFLCFJD_02991 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GKFLCFJD_02992 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
GKFLCFJD_02993 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GKFLCFJD_02994 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_02995 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_02996 1.6e-103 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
GKFLCFJD_02997 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
GKFLCFJD_02998 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
GKFLCFJD_02999 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
GKFLCFJD_03000 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
GKFLCFJD_03001 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKFLCFJD_03002 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKFLCFJD_03003 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GKFLCFJD_03004 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
GKFLCFJD_03006 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
GKFLCFJD_03007 1.28e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
GKFLCFJD_03008 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
GKFLCFJD_03009 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_03010 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GKFLCFJD_03011 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
GKFLCFJD_03012 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKFLCFJD_03013 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
GKFLCFJD_03014 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
GKFLCFJD_03015 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GKFLCFJD_03016 6.77e-219 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKFLCFJD_03017 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKFLCFJD_03018 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKFLCFJD_03019 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKFLCFJD_03020 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
GKFLCFJD_03021 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
GKFLCFJD_03022 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
GKFLCFJD_03023 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
GKFLCFJD_03024 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
GKFLCFJD_03026 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
GKFLCFJD_03027 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
GKFLCFJD_03028 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
GKFLCFJD_03029 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
GKFLCFJD_03030 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
GKFLCFJD_03031 1.47e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
GKFLCFJD_03032 1.05e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
GKFLCFJD_03033 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
GKFLCFJD_03034 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
GKFLCFJD_03035 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
GKFLCFJD_03036 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
GKFLCFJD_03037 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
GKFLCFJD_03038 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
GKFLCFJD_03039 1.27e-59 ysdA - - S - - - Membrane
GKFLCFJD_03040 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKFLCFJD_03041 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GKFLCFJD_03042 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKFLCFJD_03044 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GKFLCFJD_03045 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GKFLCFJD_03046 2.9e-168 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
GKFLCFJD_03047 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_03048 2.07e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
GKFLCFJD_03049 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKFLCFJD_03050 5.98e-206 ytxC - - S - - - YtxC-like family
GKFLCFJD_03051 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
GKFLCFJD_03052 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GKFLCFJD_03053 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
GKFLCFJD_03054 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKFLCFJD_03055 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GKFLCFJD_03056 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKFLCFJD_03057 9.85e-88 ytcD - - K - - - Transcriptional regulator
GKFLCFJD_03058 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
GKFLCFJD_03059 4.54e-205 ytbE - - S - - - reductase
GKFLCFJD_03060 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKFLCFJD_03061 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
GKFLCFJD_03062 7e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKFLCFJD_03063 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKFLCFJD_03064 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
GKFLCFJD_03065 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_03066 2.55e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
GKFLCFJD_03067 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
GKFLCFJD_03068 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GKFLCFJD_03069 9.38e-95 ytwI - - S - - - membrane
GKFLCFJD_03070 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
GKFLCFJD_03071 5.68e-83 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
GKFLCFJD_03072 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GKFLCFJD_03073 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GKFLCFJD_03074 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GKFLCFJD_03075 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GKFLCFJD_03076 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
GKFLCFJD_03077 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GKFLCFJD_03078 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
GKFLCFJD_03079 5.12e-112 ytrI - - - - - - -
GKFLCFJD_03080 1.15e-39 - - - - - - - -
GKFLCFJD_03081 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
GKFLCFJD_03082 2.15e-63 ytpI - - S - - - YtpI-like protein
GKFLCFJD_03083 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
GKFLCFJD_03084 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
GKFLCFJD_03085 2.09e-306 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
GKFLCFJD_03086 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
GKFLCFJD_03087 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKFLCFJD_03088 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
GKFLCFJD_03089 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKFLCFJD_03090 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GKFLCFJD_03091 4.08e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKFLCFJD_03092 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKFLCFJD_03093 4.01e-194 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
GKFLCFJD_03094 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
GKFLCFJD_03095 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GKFLCFJD_03096 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
GKFLCFJD_03097 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
GKFLCFJD_03098 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_03100 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
GKFLCFJD_03101 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GKFLCFJD_03102 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
GKFLCFJD_03103 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKFLCFJD_03104 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
GKFLCFJD_03105 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKFLCFJD_03106 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
GKFLCFJD_03107 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
GKFLCFJD_03108 7.05e-113 yteJ - - S - - - RDD family
GKFLCFJD_03109 6.13e-233 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
GKFLCFJD_03110 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKFLCFJD_03111 0.0 ytcJ - - S - - - amidohydrolase
GKFLCFJD_03112 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GKFLCFJD_03113 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
GKFLCFJD_03114 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKFLCFJD_03115 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GKFLCFJD_03116 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GKFLCFJD_03117 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKFLCFJD_03118 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
GKFLCFJD_03119 2.94e-142 yttP - - K - - - Transcriptional regulator
GKFLCFJD_03120 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GKFLCFJD_03121 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
GKFLCFJD_03122 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKFLCFJD_03124 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKFLCFJD_03125 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GKFLCFJD_03126 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
GKFLCFJD_03127 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
GKFLCFJD_03128 6.51e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
GKFLCFJD_03129 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
GKFLCFJD_03130 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
GKFLCFJD_03131 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GKFLCFJD_03132 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
GKFLCFJD_03133 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
GKFLCFJD_03134 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
GKFLCFJD_03135 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKFLCFJD_03136 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GKFLCFJD_03137 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GKFLCFJD_03138 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKFLCFJD_03139 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
GKFLCFJD_03140 3.17e-75 ytpP - - CO - - - Thioredoxin
GKFLCFJD_03141 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
GKFLCFJD_03142 2.24e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
GKFLCFJD_03143 4.06e-68 ytzB - - S - - - small secreted protein
GKFLCFJD_03144 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
GKFLCFJD_03145 2.16e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GKFLCFJD_03146 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKFLCFJD_03147 9.51e-61 ytzH - - S - - - YtzH-like protein
GKFLCFJD_03148 3.02e-192 ytmP - - M - - - Phosphotransferase
GKFLCFJD_03149 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GKFLCFJD_03150 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
GKFLCFJD_03151 4.92e-212 ytlQ - - - - - - -
GKFLCFJD_03152 7.71e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GKFLCFJD_03153 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GKFLCFJD_03154 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
GKFLCFJD_03155 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
GKFLCFJD_03156 8.45e-263 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
GKFLCFJD_03157 2.4e-169 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKFLCFJD_03158 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
GKFLCFJD_03159 9.04e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKFLCFJD_03160 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKFLCFJD_03161 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
GKFLCFJD_03162 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
GKFLCFJD_03163 2.14e-36 yteV - - S - - - Sporulation protein Cse60
GKFLCFJD_03164 1.97e-152 yteU - - S - - - Integral membrane protein
GKFLCFJD_03165 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
GKFLCFJD_03166 5.81e-95 yteS - - G - - - transport
GKFLCFJD_03167 2.23e-286 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
GKFLCFJD_03168 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
GKFLCFJD_03169 0.0 ytdP - - K - - - Transcriptional regulator
GKFLCFJD_03170 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
GKFLCFJD_03171 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
GKFLCFJD_03172 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
GKFLCFJD_03173 2.64e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKFLCFJD_03174 4.57e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GKFLCFJD_03175 5.04e-164 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GKFLCFJD_03176 3.73e-284 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GKFLCFJD_03177 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
GKFLCFJD_03178 4.04e-182 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GKFLCFJD_03179 1.43e-222 - - - S - - - Acetyl xylan esterase (AXE1)
GKFLCFJD_03180 1.12e-244 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_03181 4.68e-315 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKFLCFJD_03182 2.86e-215 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKFLCFJD_03183 1.32e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
GKFLCFJD_03184 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
GKFLCFJD_03185 1.22e-68 ytwF - - P - - - Sulfurtransferase
GKFLCFJD_03186 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GKFLCFJD_03187 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
GKFLCFJD_03188 6.61e-184 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
GKFLCFJD_03189 2.98e-269 yttB - - EGP - - - Major facilitator superfamily
GKFLCFJD_03190 2.02e-78 yttA - - S - - - Pfam Transposase IS66
GKFLCFJD_03191 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
GKFLCFJD_03192 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_03193 1.58e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
GKFLCFJD_03194 1.77e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_03195 5.92e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GKFLCFJD_03196 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_03197 1.07e-189 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
GKFLCFJD_03198 3.35e-222 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GKFLCFJD_03199 1.03e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_03200 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
GKFLCFJD_03202 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
GKFLCFJD_03203 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
GKFLCFJD_03204 6.76e-137 ytqB - - J - - - Putative rRNA methylase
GKFLCFJD_03205 1.96e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
GKFLCFJD_03206 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
GKFLCFJD_03207 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GKFLCFJD_03208 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GKFLCFJD_03209 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GKFLCFJD_03210 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKFLCFJD_03211 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GKFLCFJD_03212 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
GKFLCFJD_03213 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
GKFLCFJD_03214 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GKFLCFJD_03215 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKFLCFJD_03216 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GKFLCFJD_03217 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GKFLCFJD_03218 1.59e-81 ytkC - - S - - - Bacteriophage holin family
GKFLCFJD_03219 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GKFLCFJD_03221 8.26e-96 ytkA - - S - - - YtkA-like
GKFLCFJD_03222 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKFLCFJD_03223 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
GKFLCFJD_03224 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GKFLCFJD_03225 2.81e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
GKFLCFJD_03226 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
GKFLCFJD_03227 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
GKFLCFJD_03228 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
GKFLCFJD_03229 1.64e-299 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GKFLCFJD_03230 1.83e-180 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GKFLCFJD_03231 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKFLCFJD_03232 1.22e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GKFLCFJD_03233 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GKFLCFJD_03234 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GKFLCFJD_03235 5.09e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
GKFLCFJD_03236 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GKFLCFJD_03237 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
GKFLCFJD_03238 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
GKFLCFJD_03239 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
GKFLCFJD_03240 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKFLCFJD_03241 7.74e-231 ytcB - - M - - - NAD-dependent epimerase dehydratase
GKFLCFJD_03242 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
GKFLCFJD_03244 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
GKFLCFJD_03245 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
GKFLCFJD_03246 9.43e-263 cotI - - S ko:K06331 - ko00000 Spore coat protein
GKFLCFJD_03247 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
GKFLCFJD_03248 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GKFLCFJD_03249 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
GKFLCFJD_03250 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
GKFLCFJD_03251 2.96e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GKFLCFJD_03252 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GKFLCFJD_03274 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKFLCFJD_03275 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
GKFLCFJD_03276 1.2e-122 - - - M - - - FR47-like protein
GKFLCFJD_03277 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
GKFLCFJD_03278 4.06e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
GKFLCFJD_03279 1.95e-109 yuaE - - S - - - DinB superfamily
GKFLCFJD_03280 8.58e-139 yuaD - - - - - - -
GKFLCFJD_03281 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
GKFLCFJD_03282 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKFLCFJD_03283 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
GKFLCFJD_03284 5.83e-118 yuaB - - - - - - -
GKFLCFJD_03285 1.83e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
GKFLCFJD_03286 1.85e-301 - - - P ko:K03498 - ko00000,ko02000 Potassium
GKFLCFJD_03287 3.31e-52 yubF - - S - - - yiaA/B two helix domain
GKFLCFJD_03288 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKFLCFJD_03289 0.0 yubD - - P - - - Major Facilitator Superfamily
GKFLCFJD_03290 6.82e-114 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
GKFLCFJD_03292 6.02e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GKFLCFJD_03293 3.8e-256 yubA - - S - - - transporter activity
GKFLCFJD_03294 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GKFLCFJD_03295 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
GKFLCFJD_03296 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
GKFLCFJD_03297 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
GKFLCFJD_03298 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GKFLCFJD_03299 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
GKFLCFJD_03300 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKFLCFJD_03301 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKFLCFJD_03302 6.34e-300 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKFLCFJD_03303 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKFLCFJD_03304 1.06e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
GKFLCFJD_03305 5e-48 - - - - - - - -
GKFLCFJD_03306 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
GKFLCFJD_03307 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GKFLCFJD_03308 1.07e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GKFLCFJD_03309 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
GKFLCFJD_03310 1.35e-51 - - - - - - - -
GKFLCFJD_03311 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
GKFLCFJD_03312 1.76e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
GKFLCFJD_03313 4.22e-95 yugN - - S - - - YugN-like family
GKFLCFJD_03315 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GKFLCFJD_03316 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
GKFLCFJD_03317 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
GKFLCFJD_03318 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
GKFLCFJD_03319 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
GKFLCFJD_03320 6.62e-256 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
GKFLCFJD_03321 6.74e-112 alaR - - K - - - Transcriptional regulator
GKFLCFJD_03322 1.2e-201 yugF - - I - - - Hydrolase
GKFLCFJD_03323 6.7e-56 yugE - - S - - - Domain of unknown function (DUF1871)
GKFLCFJD_03324 2.09e-289 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GKFLCFJD_03325 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_03326 4.3e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
GKFLCFJD_03327 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
GKFLCFJD_03329 1.96e-245 yuxJ - - EGP - - - Major facilitator superfamily
GKFLCFJD_03330 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
GKFLCFJD_03331 3.31e-98 yuxK - - S - - - protein conserved in bacteria
GKFLCFJD_03332 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
GKFLCFJD_03333 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GKFLCFJD_03334 1.14e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
GKFLCFJD_03335 6.34e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
GKFLCFJD_03336 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_03337 1.57e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKFLCFJD_03338 1.47e-216 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKFLCFJD_03339 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
GKFLCFJD_03340 7.06e-22 - - - - - - - -
GKFLCFJD_03341 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GKFLCFJD_03342 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKFLCFJD_03343 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKFLCFJD_03344 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKFLCFJD_03345 7.39e-103 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKFLCFJD_03346 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKFLCFJD_03347 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
GKFLCFJD_03348 3.18e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
GKFLCFJD_03349 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKFLCFJD_03350 4.23e-276 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_03351 3.27e-246 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_03353 1.4e-209 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
GKFLCFJD_03354 6.29e-10 - - - S - - - DegQ (SacQ) family
GKFLCFJD_03355 9.63e-08 - - - - - - - -
GKFLCFJD_03356 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
GKFLCFJD_03357 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKFLCFJD_03358 5.65e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
GKFLCFJD_03359 1.32e-88 - - - S - - - Protein of unknown function (DUF1694)
GKFLCFJD_03360 1.63e-52 yueH - - S - - - YueH-like protein
GKFLCFJD_03361 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
GKFLCFJD_03362 4.72e-245 yueF - - S - - - transporter activity
GKFLCFJD_03363 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
GKFLCFJD_03364 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
GKFLCFJD_03365 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
GKFLCFJD_03366 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_03367 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
GKFLCFJD_03368 0.0 yueB - - S - - - type VII secretion protein EsaA
GKFLCFJD_03369 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GKFLCFJD_03370 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
GKFLCFJD_03371 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
GKFLCFJD_03372 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
GKFLCFJD_03373 1.03e-292 yukF - - QT - - - Transcriptional regulator
GKFLCFJD_03374 4.9e-263 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
GKFLCFJD_03375 2.07e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
GKFLCFJD_03376 1.42e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
GKFLCFJD_03377 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_03378 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
GKFLCFJD_03379 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
GKFLCFJD_03380 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
GKFLCFJD_03381 1.43e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_03382 1.55e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
GKFLCFJD_03383 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
GKFLCFJD_03384 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
GKFLCFJD_03385 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
GKFLCFJD_03386 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GKFLCFJD_03387 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
GKFLCFJD_03388 3.28e-151 yuiC - - S - - - protein conserved in bacteria
GKFLCFJD_03389 9.78e-47 yuiB - - S - - - Putative membrane protein
GKFLCFJD_03390 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKFLCFJD_03391 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
GKFLCFJD_03393 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKFLCFJD_03394 2.96e-151 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
GKFLCFJD_03395 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKFLCFJD_03396 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
GKFLCFJD_03397 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKFLCFJD_03398 1.54e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKFLCFJD_03399 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
GKFLCFJD_03400 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKFLCFJD_03401 6.61e-75 yuzD - - S - - - protein conserved in bacteria
GKFLCFJD_03402 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
GKFLCFJD_03403 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
GKFLCFJD_03404 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GKFLCFJD_03405 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GKFLCFJD_03406 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GKFLCFJD_03407 4.63e-255 yutH - - S - - - Spore coat protein
GKFLCFJD_03408 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
GKFLCFJD_03409 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKFLCFJD_03410 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
GKFLCFJD_03411 3.2e-63 yutD - - S - - - protein conserved in bacteria
GKFLCFJD_03412 9.45e-145 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GKFLCFJD_03413 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GKFLCFJD_03414 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
GKFLCFJD_03415 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
GKFLCFJD_03416 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
GKFLCFJD_03417 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKFLCFJD_03418 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
GKFLCFJD_03419 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
GKFLCFJD_03420 2.72e-82 yunG - - - - - - -
GKFLCFJD_03421 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
GKFLCFJD_03422 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
GKFLCFJD_03423 1.46e-300 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
GKFLCFJD_03424 1.65e-285 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
GKFLCFJD_03425 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
GKFLCFJD_03426 1.41e-79 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
GKFLCFJD_03427 1.3e-126 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
GKFLCFJD_03428 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
GKFLCFJD_03429 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
GKFLCFJD_03430 2.62e-144 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
GKFLCFJD_03431 5.12e-243 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GKFLCFJD_03433 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
GKFLCFJD_03434 4.9e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GKFLCFJD_03435 6.53e-218 bsn - - L - - - Ribonuclease
GKFLCFJD_03436 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKFLCFJD_03437 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
GKFLCFJD_03438 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
GKFLCFJD_03439 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
GKFLCFJD_03440 1.24e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKFLCFJD_03441 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
GKFLCFJD_03442 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GKFLCFJD_03443 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
GKFLCFJD_03444 1.42e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
GKFLCFJD_03446 3.35e-56 - - - - - - - -
GKFLCFJD_03447 2.14e-87 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKFLCFJD_03448 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
GKFLCFJD_03449 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
GKFLCFJD_03450 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKFLCFJD_03451 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
GKFLCFJD_03452 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GKFLCFJD_03453 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GKFLCFJD_03454 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
GKFLCFJD_03455 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
GKFLCFJD_03456 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKFLCFJD_03457 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
GKFLCFJD_03458 2e-73 yusE - - CO - - - Thioredoxin
GKFLCFJD_03459 1.32e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
GKFLCFJD_03460 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
GKFLCFJD_03461 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
GKFLCFJD_03462 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GKFLCFJD_03463 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
GKFLCFJD_03464 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
GKFLCFJD_03465 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
GKFLCFJD_03466 2.86e-14 - - - S - - - YuzL-like protein
GKFLCFJD_03467 2.09e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
GKFLCFJD_03468 2.23e-54 - - - - - - - -
GKFLCFJD_03469 2.12e-70 yusN - - M - - - Coat F domain
GKFLCFJD_03470 3.83e-99 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
GKFLCFJD_03471 0.0 yusP - - P - - - Major facilitator superfamily
GKFLCFJD_03472 1.76e-86 yusQ - - S - - - Tautomerase enzyme
GKFLCFJD_03473 6.81e-82 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_03474 4.48e-67 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_03475 1.52e-206 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
GKFLCFJD_03476 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
GKFLCFJD_03477 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKFLCFJD_03478 2.01e-87 - - - S - - - YusW-like protein
GKFLCFJD_03479 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
GKFLCFJD_03480 1.21e-41 pepF2 - - E - - - COG1164 Oligoendopeptidase F
GKFLCFJD_03481 6.65e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_03482 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
GKFLCFJD_03483 9.63e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKFLCFJD_03484 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_03485 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_03486 3.06e-204 yuxN - - K - - - Transcriptional regulator
GKFLCFJD_03487 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GKFLCFJD_03488 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
GKFLCFJD_03489 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
GKFLCFJD_03490 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
GKFLCFJD_03491 1.22e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
GKFLCFJD_03492 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKFLCFJD_03493 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_03494 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
GKFLCFJD_03495 6.57e-178 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GKFLCFJD_03496 4.22e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
GKFLCFJD_03497 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
GKFLCFJD_03498 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_03499 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
GKFLCFJD_03500 0.0 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GKFLCFJD_03501 3.29e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_03502 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GKFLCFJD_03503 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_03504 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
GKFLCFJD_03505 0.0 yvrG - - T - - - Histidine kinase
GKFLCFJD_03506 2.08e-169 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_03507 5.07e-32 - - - - - - - -
GKFLCFJD_03508 6.74e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
GKFLCFJD_03509 3.46e-26 - - - S - - - YvrJ protein family
GKFLCFJD_03510 1.59e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
GKFLCFJD_03511 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
GKFLCFJD_03512 1.17e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GKFLCFJD_03513 1.62e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_03514 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
GKFLCFJD_03515 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKFLCFJD_03516 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_03517 1.48e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKFLCFJD_03518 1.14e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKFLCFJD_03520 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GKFLCFJD_03521 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
GKFLCFJD_03522 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
GKFLCFJD_03523 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
GKFLCFJD_03524 5.58e-218 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
GKFLCFJD_03525 6.57e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
GKFLCFJD_03526 6.08e-154 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
GKFLCFJD_03527 4.54e-203 yvgN - - S - - - reductase
GKFLCFJD_03528 7.97e-113 yvgO - - - - - - -
GKFLCFJD_03529 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
GKFLCFJD_03530 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
GKFLCFJD_03531 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GKFLCFJD_03532 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKFLCFJD_03533 3.88e-140 yvgT - - S - - - membrane
GKFLCFJD_03534 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
GKFLCFJD_03535 3.45e-137 bdbD - - O - - - Thioredoxin
GKFLCFJD_03536 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
GKFLCFJD_03537 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GKFLCFJD_03538 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
GKFLCFJD_03539 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
GKFLCFJD_03540 7.89e-254 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GKFLCFJD_03541 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GKFLCFJD_03542 0.0 - - - S - - - Fusaric acid resistance protein-like
GKFLCFJD_03543 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
GKFLCFJD_03544 4.28e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
GKFLCFJD_03545 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
GKFLCFJD_03546 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_03548 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GKFLCFJD_03549 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKFLCFJD_03550 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
GKFLCFJD_03551 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
GKFLCFJD_03552 4.03e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
GKFLCFJD_03553 3.44e-48 yvzC - - K - - - transcriptional
GKFLCFJD_03554 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
GKFLCFJD_03555 1.19e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
GKFLCFJD_03556 3.85e-72 yvaP - - K - - - transcriptional
GKFLCFJD_03557 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKFLCFJD_03558 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GKFLCFJD_03559 2.89e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GKFLCFJD_03560 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GKFLCFJD_03561 6.29e-272 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GKFLCFJD_03562 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
GKFLCFJD_03563 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
GKFLCFJD_03564 4.79e-224 - - - - - - - -
GKFLCFJD_03566 8.32e-133 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
GKFLCFJD_03567 9.63e-60 sdpR - - K - - - transcriptional
GKFLCFJD_03568 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GKFLCFJD_03569 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GKFLCFJD_03570 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GKFLCFJD_03571 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GKFLCFJD_03572 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
GKFLCFJD_03573 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
GKFLCFJD_03574 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
GKFLCFJD_03575 2.38e-158 yvbI - - M - - - Membrane
GKFLCFJD_03576 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
GKFLCFJD_03577 2.4e-106 yvbK - - K - - - acetyltransferase
GKFLCFJD_03578 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKFLCFJD_03579 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
GKFLCFJD_03580 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKFLCFJD_03581 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GKFLCFJD_03582 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKFLCFJD_03583 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GKFLCFJD_03584 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKFLCFJD_03585 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
GKFLCFJD_03586 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKFLCFJD_03587 3.45e-206 yvbU - - K - - - Transcriptional regulator
GKFLCFJD_03588 2.37e-199 yvbV - - EG - - - EamA-like transporter family
GKFLCFJD_03589 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GKFLCFJD_03590 2.68e-252 - - - S - - - Glycosyl hydrolase
GKFLCFJD_03591 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GKFLCFJD_03592 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
GKFLCFJD_03593 5.47e-176 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GKFLCFJD_03594 7.53e-137 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKFLCFJD_03595 1.76e-257 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_03596 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
GKFLCFJD_03597 1.03e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
GKFLCFJD_03598 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
GKFLCFJD_03599 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
GKFLCFJD_03600 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
GKFLCFJD_03601 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
GKFLCFJD_03602 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
GKFLCFJD_03603 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
GKFLCFJD_03604 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
GKFLCFJD_03605 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_03606 9.32e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
GKFLCFJD_03607 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GKFLCFJD_03608 2.57e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GKFLCFJD_03609 5.69e-44 yvfG - - S - - - YvfG protein
GKFLCFJD_03610 1.85e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
GKFLCFJD_03611 1.2e-284 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
GKFLCFJD_03612 6.53e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
GKFLCFJD_03613 1.65e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GKFLCFJD_03614 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKFLCFJD_03615 4.44e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GKFLCFJD_03616 5.09e-264 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
GKFLCFJD_03617 6.3e-251 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
GKFLCFJD_03618 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
GKFLCFJD_03619 7.49e-280 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GKFLCFJD_03620 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
GKFLCFJD_03621 2.95e-286 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
GKFLCFJD_03622 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
GKFLCFJD_03623 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
GKFLCFJD_03624 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
GKFLCFJD_03625 2.15e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
GKFLCFJD_03626 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
GKFLCFJD_03628 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
GKFLCFJD_03629 5.1e-64 - - - S - - - Protein of unknown function (DUF3237)
GKFLCFJD_03630 1.51e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GKFLCFJD_03631 0.0 pbpE - - V - - - Beta-lactamase
GKFLCFJD_03632 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
GKFLCFJD_03633 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
GKFLCFJD_03634 0.0 ybeC - - E - - - amino acid
GKFLCFJD_03635 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
GKFLCFJD_03636 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
GKFLCFJD_03637 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
GKFLCFJD_03638 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
GKFLCFJD_03639 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
GKFLCFJD_03640 1.99e-235 - - - S - - - Patatin-like phospholipase
GKFLCFJD_03642 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKFLCFJD_03643 1.01e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GKFLCFJD_03644 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GKFLCFJD_03645 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
GKFLCFJD_03646 2.42e-203 malA - - S - - - Protein of unknown function (DUF1189)
GKFLCFJD_03647 1.18e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
GKFLCFJD_03648 2.12e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
GKFLCFJD_03649 1.03e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
GKFLCFJD_03650 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
GKFLCFJD_03651 2.28e-223 yvdE - - K - - - Transcriptional regulator
GKFLCFJD_03652 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GKFLCFJD_03653 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
GKFLCFJD_03654 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
GKFLCFJD_03655 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
GKFLCFJD_03656 1.4e-235 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKFLCFJD_03657 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
GKFLCFJD_03658 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_03659 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
GKFLCFJD_03660 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_03661 1.37e-45 - - - - - - - -
GKFLCFJD_03662 5.24e-188 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
GKFLCFJD_03663 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
GKFLCFJD_03664 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GKFLCFJD_03665 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GKFLCFJD_03666 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GKFLCFJD_03667 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GKFLCFJD_03668 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKFLCFJD_03669 3.05e-190 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
GKFLCFJD_03670 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
GKFLCFJD_03671 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GKFLCFJD_03673 0.0 - - - - - - - -
GKFLCFJD_03674 6.36e-172 - - - - - - - -
GKFLCFJD_03675 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
GKFLCFJD_03676 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GKFLCFJD_03677 1.44e-170 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GKFLCFJD_03678 7.21e-150 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GKFLCFJD_03679 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
GKFLCFJD_03680 1.19e-297 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GKFLCFJD_03681 9.09e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GKFLCFJD_03682 2.07e-282 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GKFLCFJD_03683 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
GKFLCFJD_03684 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
GKFLCFJD_03685 5.29e-121 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
GKFLCFJD_03686 4.51e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
GKFLCFJD_03687 3.19e-212 yvoD - - P - - - COG0370 Fe2 transport system protein B
GKFLCFJD_03688 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKFLCFJD_03689 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKFLCFJD_03690 2.25e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKFLCFJD_03691 1.39e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKFLCFJD_03692 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
GKFLCFJD_03693 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
GKFLCFJD_03694 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_03695 1.61e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKFLCFJD_03696 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
GKFLCFJD_03697 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_03698 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
GKFLCFJD_03699 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
GKFLCFJD_03700 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
GKFLCFJD_03701 5.8e-221 yvlB - - S - - - Putative adhesin
GKFLCFJD_03702 8.09e-65 yvlA - - - - - - -
GKFLCFJD_03703 2.73e-46 yvkN - - - - - - -
GKFLCFJD_03704 2.57e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GKFLCFJD_03705 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GKFLCFJD_03706 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKFLCFJD_03707 2.54e-42 csbA - - S - - - protein conserved in bacteria
GKFLCFJD_03708 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
GKFLCFJD_03709 1.43e-131 yvkB - - K - - - Transcriptional regulator
GKFLCFJD_03710 5.47e-298 yvkA - - P - - - -transporter
GKFLCFJD_03711 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKFLCFJD_03712 1.38e-73 swrA - - S - - - Swarming motility protein
GKFLCFJD_03713 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
GKFLCFJD_03714 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GKFLCFJD_03715 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
GKFLCFJD_03716 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
GKFLCFJD_03717 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKFLCFJD_03718 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKFLCFJD_03719 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKFLCFJD_03720 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKFLCFJD_03721 9.14e-88 - - - - - - - -
GKFLCFJD_03722 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
GKFLCFJD_03723 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
GKFLCFJD_03724 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GKFLCFJD_03725 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
GKFLCFJD_03726 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GKFLCFJD_03727 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GKFLCFJD_03728 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GKFLCFJD_03729 4.19e-93 yviE - - - - - - -
GKFLCFJD_03730 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
GKFLCFJD_03731 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
GKFLCFJD_03732 3.5e-102 yvyG - - NOU - - - FlgN protein
GKFLCFJD_03733 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
GKFLCFJD_03734 1.83e-96 yvyF - - S - - - flagellar protein
GKFLCFJD_03735 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
GKFLCFJD_03736 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
GKFLCFJD_03737 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GKFLCFJD_03738 2.15e-199 degV - - S - - - protein conserved in bacteria
GKFLCFJD_03739 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKFLCFJD_03740 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GKFLCFJD_03741 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
GKFLCFJD_03742 3.99e-225 yvhJ - - K - - - Transcriptional regulator
GKFLCFJD_03743 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
GKFLCFJD_03744 3.3e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
GKFLCFJD_03745 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
GKFLCFJD_03746 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
GKFLCFJD_03747 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
GKFLCFJD_03748 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKFLCFJD_03749 8.77e-283 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
GKFLCFJD_03750 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKFLCFJD_03751 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GKFLCFJD_03752 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GKFLCFJD_03753 0.0 lytB - - D - - - Stage II sporulation protein
GKFLCFJD_03754 3.26e-50 - - - - - - - -
GKFLCFJD_03755 2.77e-219 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GKFLCFJD_03756 6.61e-278 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKFLCFJD_03757 1.78e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GKFLCFJD_03758 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GKFLCFJD_03759 0.0 - - - M - - - Glycosyltransferase like family 2
GKFLCFJD_03760 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
GKFLCFJD_03761 2.13e-127 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GKFLCFJD_03762 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GKFLCFJD_03763 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
GKFLCFJD_03764 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKFLCFJD_03765 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
GKFLCFJD_03766 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
GKFLCFJD_03767 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GKFLCFJD_03768 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKFLCFJD_03769 0.0 - - - - - - - -
GKFLCFJD_03770 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKFLCFJD_03771 1.16e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKFLCFJD_03772 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
GKFLCFJD_03773 1.24e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
GKFLCFJD_03774 2.29e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
GKFLCFJD_03775 8.19e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKFLCFJD_03776 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
GKFLCFJD_03777 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GKFLCFJD_03778 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GKFLCFJD_03779 2.29e-29 ywtC - - - - - - -
GKFLCFJD_03780 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
GKFLCFJD_03781 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
GKFLCFJD_03782 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
GKFLCFJD_03783 2.3e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
GKFLCFJD_03784 6.44e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKFLCFJD_03785 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GKFLCFJD_03786 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GKFLCFJD_03787 2.87e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKFLCFJD_03788 1.34e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
GKFLCFJD_03789 2.49e-122 batE - - T - - - Sh3 type 3 domain protein
GKFLCFJD_03790 9.2e-64 ywsA - - S - - - Protein of unknown function (DUF3892)
GKFLCFJD_03791 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
GKFLCFJD_03792 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
GKFLCFJD_03793 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GKFLCFJD_03794 3.36e-218 alsR - - K - - - LysR substrate binding domain
GKFLCFJD_03795 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GKFLCFJD_03796 9.09e-164 ywrJ - - - - - - -
GKFLCFJD_03797 1.02e-196 cotB - - - ko:K06325 - ko00000 -
GKFLCFJD_03798 1.12e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
GKFLCFJD_03799 2.17e-16 - - - - - - - -
GKFLCFJD_03800 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GKFLCFJD_03801 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
GKFLCFJD_03802 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
GKFLCFJD_03803 4.83e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
GKFLCFJD_03804 5.52e-133 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
GKFLCFJD_03805 3.66e-115 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
GKFLCFJD_03807 3.83e-132 ywqN - - S - - - NAD(P)H-dependent
GKFLCFJD_03808 1.16e-209 - - - K - - - Transcriptional regulator
GKFLCFJD_03809 7.78e-176 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
GKFLCFJD_03810 1.36e-71 - - - S - - - MORN repeat variant
GKFLCFJD_03811 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
GKFLCFJD_03812 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
GKFLCFJD_03814 2.52e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
GKFLCFJD_03815 9.82e-315 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKFLCFJD_03816 3.16e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
GKFLCFJD_03817 4.51e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
GKFLCFJD_03818 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
GKFLCFJD_03819 3.6e-25 - - - - - - - -
GKFLCFJD_03820 0.0 ywqB - - S - - - SWIM zinc finger
GKFLCFJD_03821 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
GKFLCFJD_03822 4.53e-203 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GKFLCFJD_03823 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GKFLCFJD_03824 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
GKFLCFJD_03825 5.26e-88 ywpG - - - - - - -
GKFLCFJD_03826 8.81e-89 ywpF - - S - - - YwpF-like protein
GKFLCFJD_03827 4.63e-68 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GKFLCFJD_03828 2.55e-197 ywpD - - T - - - Histidine kinase
GKFLCFJD_03829 1.13e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKFLCFJD_03830 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKFLCFJD_03831 5.45e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
GKFLCFJD_03832 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
GKFLCFJD_03833 6.18e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
GKFLCFJD_03834 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
GKFLCFJD_03835 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
GKFLCFJD_03836 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
GKFLCFJD_03837 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_03838 1.02e-312 ywoF - - P - - - Right handed beta helix region
GKFLCFJD_03839 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
GKFLCFJD_03840 8e-309 ywoD - - EGP - - - Major facilitator superfamily
GKFLCFJD_03841 2.56e-134 yjgF - - Q - - - Isochorismatase family
GKFLCFJD_03842 3.04e-102 - - - - - - - -
GKFLCFJD_03843 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
GKFLCFJD_03844 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
GKFLCFJD_03845 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
GKFLCFJD_03846 1.63e-95 ywnJ - - S - - - VanZ like family
GKFLCFJD_03847 2.13e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
GKFLCFJD_03848 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
GKFLCFJD_03849 3.28e-22 ywnC - - S - - - Family of unknown function (DUF5362)
GKFLCFJD_03850 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
GKFLCFJD_03851 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKFLCFJD_03852 3.41e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
GKFLCFJD_03853 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
GKFLCFJD_03854 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
GKFLCFJD_03855 4.58e-85 ywnA - - K - - - Transcriptional regulator
GKFLCFJD_03856 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GKFLCFJD_03857 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
GKFLCFJD_03858 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
GKFLCFJD_03860 1.11e-21 csbD - - K - - - CsbD-like
GKFLCFJD_03861 1.12e-109 ywmF - - S - - - Peptidase M50
GKFLCFJD_03862 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
GKFLCFJD_03863 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GKFLCFJD_03864 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GKFLCFJD_03866 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GKFLCFJD_03867 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GKFLCFJD_03868 3.72e-238 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
GKFLCFJD_03869 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKFLCFJD_03870 2.39e-174 ywmB - - S - - - TATA-box binding
GKFLCFJD_03871 4.54e-45 ywzB - - S - - - membrane
GKFLCFJD_03872 6.12e-115 ywmA - - - - - - -
GKFLCFJD_03873 1.04e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GKFLCFJD_03874 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKFLCFJD_03875 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKFLCFJD_03876 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKFLCFJD_03877 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKFLCFJD_03878 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKFLCFJD_03879 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKFLCFJD_03880 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GKFLCFJD_03881 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
GKFLCFJD_03882 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKFLCFJD_03883 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKFLCFJD_03884 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
GKFLCFJD_03885 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
GKFLCFJD_03886 5.75e-103 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKFLCFJD_03887 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
GKFLCFJD_03888 4.44e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKFLCFJD_03889 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
GKFLCFJD_03890 6.58e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
GKFLCFJD_03891 1.67e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
GKFLCFJD_03893 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKFLCFJD_03894 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKFLCFJD_03895 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKFLCFJD_03896 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
GKFLCFJD_03897 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
GKFLCFJD_03898 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
GKFLCFJD_03899 8.53e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GKFLCFJD_03900 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
GKFLCFJD_03901 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GKFLCFJD_03902 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
GKFLCFJD_03903 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKFLCFJD_03904 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GKFLCFJD_03905 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
GKFLCFJD_03906 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
GKFLCFJD_03907 3.31e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
GKFLCFJD_03908 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKFLCFJD_03909 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKFLCFJD_03910 2.1e-269 acdA - - I - - - acyl-CoA dehydrogenase
GKFLCFJD_03911 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
GKFLCFJD_03912 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
GKFLCFJD_03913 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
GKFLCFJD_03914 1.32e-57 ywjC - - - - - - -
GKFLCFJD_03915 1.35e-124 ywjB - - H - - - RibD C-terminal domain
GKFLCFJD_03916 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
GKFLCFJD_03917 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKFLCFJD_03918 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
GKFLCFJD_03919 6.32e-128 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
GKFLCFJD_03920 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
GKFLCFJD_03921 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKFLCFJD_03922 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
GKFLCFJD_03923 1.57e-180 ywiC - - S - - - YwiC-like protein
GKFLCFJD_03924 3.98e-169 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
GKFLCFJD_03925 3.39e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
GKFLCFJD_03926 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GKFLCFJD_03927 4.64e-96 ywiB - - S - - - protein conserved in bacteria
GKFLCFJD_03928 3.71e-12 - - - S - - - Bacteriocin subtilosin A
GKFLCFJD_03929 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
GKFLCFJD_03931 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKFLCFJD_03932 1.07e-300 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
GKFLCFJD_03933 7.55e-280 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
GKFLCFJD_03934 0.0 - - - L - - - Peptidase, M16
GKFLCFJD_03936 0.0 ywhL - - CO - - - amine dehydrogenase activity
GKFLCFJD_03937 2.36e-291 ywhK - - CO - - - amine dehydrogenase activity
GKFLCFJD_03938 2.88e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
GKFLCFJD_03940 6.61e-110 - - - S - - - Aminoacyl-tRNA editing domain
GKFLCFJD_03941 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
GKFLCFJD_03942 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GKFLCFJD_03943 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKFLCFJD_03944 1.92e-123 ywhD - - S - - - YwhD family
GKFLCFJD_03945 3.29e-154 ywhC - - S - - - Peptidase family M50
GKFLCFJD_03946 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
GKFLCFJD_03947 1.76e-94 ywhA - - K - - - Transcriptional regulator
GKFLCFJD_03948 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKFLCFJD_03950 2.66e-307 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
GKFLCFJD_03951 1.1e-103 yffB - - K - - - Transcriptional regulator
GKFLCFJD_03952 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
GKFLCFJD_03953 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
GKFLCFJD_03954 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
GKFLCFJD_03955 5.65e-147 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
GKFLCFJD_03956 1.57e-204 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
GKFLCFJD_03957 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
GKFLCFJD_03958 9.56e-212 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_03959 7.1e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
GKFLCFJD_03960 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
GKFLCFJD_03961 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
GKFLCFJD_03962 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
GKFLCFJD_03963 1.36e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
GKFLCFJD_03964 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
GKFLCFJD_03965 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKFLCFJD_03966 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
GKFLCFJD_03967 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
GKFLCFJD_03968 1.89e-275 ywfA - - EGP - - - -transporter
GKFLCFJD_03969 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKFLCFJD_03970 0.0 rocB - - E - - - arginine degradation protein
GKFLCFJD_03971 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
GKFLCFJD_03972 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GKFLCFJD_03973 1.1e-102 - - - - - - - -
GKFLCFJD_03974 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
GKFLCFJD_03975 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GKFLCFJD_03976 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GKFLCFJD_03977 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKFLCFJD_03978 2.54e-243 spsG - - M - - - Spore Coat
GKFLCFJD_03979 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
GKFLCFJD_03980 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
GKFLCFJD_03981 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
GKFLCFJD_03982 4.54e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
GKFLCFJD_03983 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
GKFLCFJD_03984 4.87e-188 spsA - - M - - - Spore Coat
GKFLCFJD_03985 7.61e-114 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
GKFLCFJD_03986 1.59e-78 ywdK - - S - - - small membrane protein
GKFLCFJD_03987 4.57e-304 ywdJ - - F - - - Xanthine uracil
GKFLCFJD_03988 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
GKFLCFJD_03989 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKFLCFJD_03990 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKFLCFJD_03991 5.69e-193 ywdF - - S - - - Glycosyltransferase like family 2
GKFLCFJD_03993 8.74e-146 ywdD - - - - - - -
GKFLCFJD_03994 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
GKFLCFJD_03995 5.43e-188 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GKFLCFJD_03996 6.19e-39 ywdA - - - - - - -
GKFLCFJD_03997 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GKFLCFJD_03998 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_03999 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
GKFLCFJD_04000 4.49e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GKFLCFJD_04002 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKFLCFJD_04003 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKFLCFJD_04004 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
GKFLCFJD_04005 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GKFLCFJD_04006 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
GKFLCFJD_04007 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
GKFLCFJD_04008 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
GKFLCFJD_04009 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GKFLCFJD_04010 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
GKFLCFJD_04011 5.11e-49 ydaS - - S - - - membrane
GKFLCFJD_04012 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GKFLCFJD_04013 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKFLCFJD_04014 3.33e-77 gtcA - - S - - - GtrA-like protein
GKFLCFJD_04015 4.16e-159 ywcC - - K - - - transcriptional regulator
GKFLCFJD_04017 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
GKFLCFJD_04018 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKFLCFJD_04019 1.08e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
GKFLCFJD_04020 3.23e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
GKFLCFJD_04021 6.21e-249 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
GKFLCFJD_04022 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
GKFLCFJD_04023 7.69e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GKFLCFJD_04024 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GKFLCFJD_04025 2.7e-203 ywbI - - K - - - Transcriptional regulator
GKFLCFJD_04026 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
GKFLCFJD_04027 1.21e-143 ywbG - - M - - - effector of murein hydrolase
GKFLCFJD_04028 1.29e-280 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
GKFLCFJD_04029 1.32e-39 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
GKFLCFJD_04030 1.3e-283 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
GKFLCFJD_04031 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
GKFLCFJD_04032 7.78e-165 ywbB - - S - - - Protein of unknown function (DUF2711)
GKFLCFJD_04033 9.36e-317 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKFLCFJD_04034 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKFLCFJD_04035 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_04036 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GKFLCFJD_04037 6.53e-217 gspA - - M - - - General stress
GKFLCFJD_04038 3.96e-164 ywaF - - S - - - Integral membrane protein
GKFLCFJD_04039 2.15e-115 ywaE - - K - - - Transcriptional regulator
GKFLCFJD_04040 2.7e-298 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKFLCFJD_04041 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
GKFLCFJD_04042 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
GKFLCFJD_04043 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
GKFLCFJD_04044 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
GKFLCFJD_04045 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_04046 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
GKFLCFJD_04047 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKFLCFJD_04048 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKFLCFJD_04049 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_04050 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
GKFLCFJD_04051 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GKFLCFJD_04052 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_04053 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKFLCFJD_04054 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
GKFLCFJD_04055 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
GKFLCFJD_04056 8.94e-28 yxzF - - - - - - -
GKFLCFJD_04057 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GKFLCFJD_04058 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GKFLCFJD_04059 4.48e-277 yxlH - - EGP - - - Major Facilitator Superfamily
GKFLCFJD_04060 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GKFLCFJD_04061 2.09e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_04062 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
GKFLCFJD_04063 1.75e-43 - - - - - - - -
GKFLCFJD_04064 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
GKFLCFJD_04065 9.06e-125 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKFLCFJD_04066 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
GKFLCFJD_04067 2.01e-206 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKFLCFJD_04068 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
GKFLCFJD_04069 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
GKFLCFJD_04070 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
GKFLCFJD_04071 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
GKFLCFJD_04072 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
GKFLCFJD_04073 0.0 - - - O - - - Peptidase family M48
GKFLCFJD_04075 1.58e-200 yxkH - - G - - - Polysaccharide deacetylase
GKFLCFJD_04076 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKFLCFJD_04077 1.16e-211 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
GKFLCFJD_04078 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKFLCFJD_04079 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKFLCFJD_04080 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
GKFLCFJD_04081 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GKFLCFJD_04082 2.01e-123 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
GKFLCFJD_04083 1.53e-213 - - - K - - - LysR substrate binding domain
GKFLCFJD_04084 5.63e-102 - - - S - - - Protein of unknown function (DUF1453)
GKFLCFJD_04085 7.13e-261 - - - T - - - Signal transduction histidine kinase
GKFLCFJD_04086 5.66e-150 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
GKFLCFJD_04087 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GKFLCFJD_04090 2.57e-114 yxjI - - S - - - LURP-one-related
GKFLCFJD_04091 7.74e-280 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GKFLCFJD_04092 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GKFLCFJD_04093 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GKFLCFJD_04094 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GKFLCFJD_04095 4.65e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GKFLCFJD_04096 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
GKFLCFJD_04097 4.55e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
GKFLCFJD_04098 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKFLCFJD_04099 2.96e-29 - - - T - - - Domain of unknown function (DUF4163)
GKFLCFJD_04100 9.65e-65 yxiS - - - - - - -
GKFLCFJD_04101 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GKFLCFJD_04102 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GKFLCFJD_04103 2.62e-185 bglS - - M - - - licheninase activity
GKFLCFJD_04104 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GKFLCFJD_04105 2.75e-145 - - - - - - - -
GKFLCFJD_04106 3.97e-294 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
GKFLCFJD_04107 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
GKFLCFJD_04108 3.28e-279 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKFLCFJD_04111 5.53e-65 yxiJ - - S - - - YxiJ-like protein
GKFLCFJD_04112 3.79e-125 yxiI - - S - - - Protein of unknown function (DUF2716)
GKFLCFJD_04113 6.22e-107 - - - - - - - -
GKFLCFJD_04114 1.2e-57 - - - - - - - -
GKFLCFJD_04115 8.76e-99 yxiG - - - - - - -
GKFLCFJD_04116 1.12e-82 - - - - - - - -
GKFLCFJD_04117 3.69e-111 - - - - - - - -
GKFLCFJD_04118 1.09e-94 yxxG - - - - - - -
GKFLCFJD_04119 0.0 wapA - - M - - - COG3209 Rhs family protein
GKFLCFJD_04120 1.17e-216 yxxF - - EG - - - EamA-like transporter family
GKFLCFJD_04121 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
GKFLCFJD_04122 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKFLCFJD_04123 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_04124 1.33e-67 - - - - - - - -
GKFLCFJD_04125 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
GKFLCFJD_04126 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
GKFLCFJD_04127 2.3e-53 yxiC - - S - - - Family of unknown function (DUF5344)
GKFLCFJD_04128 1.88e-37 - - - S - - - Domain of unknown function (DUF5082)
GKFLCFJD_04129 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
GKFLCFJD_04130 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
GKFLCFJD_04131 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
GKFLCFJD_04132 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GKFLCFJD_04133 2.44e-303 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
GKFLCFJD_04134 4.15e-232 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
GKFLCFJD_04135 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKFLCFJD_04136 4.9e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
GKFLCFJD_04137 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKFLCFJD_04138 1.44e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GKFLCFJD_04139 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GKFLCFJD_04140 9.11e-198 - - - S - - - Domain of Unknown Function (DUF1206)
GKFLCFJD_04141 4.86e-259 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
GKFLCFJD_04142 0.0 yxeQ - - S - - - MmgE/PrpD family
GKFLCFJD_04143 5.21e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
GKFLCFJD_04144 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_04145 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GKFLCFJD_04146 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GKFLCFJD_04147 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKFLCFJD_04148 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKFLCFJD_04150 2.17e-243 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
GKFLCFJD_04151 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
GKFLCFJD_04154 7.32e-42 yxeE - - - - - - -
GKFLCFJD_04155 2.66e-28 yxeD - - - - - - -
GKFLCFJD_04156 6.79e-91 - - - - - - - -
GKFLCFJD_04157 9.01e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKFLCFJD_04158 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
GKFLCFJD_04159 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
GKFLCFJD_04160 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKFLCFJD_04161 4e-233 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_04162 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_04163 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
GKFLCFJD_04164 9.32e-188 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
GKFLCFJD_04165 1.87e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
GKFLCFJD_04166 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
GKFLCFJD_04167 1.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
GKFLCFJD_04168 7.09e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
GKFLCFJD_04169 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
GKFLCFJD_04170 2.13e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
GKFLCFJD_04171 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
GKFLCFJD_04172 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKFLCFJD_04173 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GKFLCFJD_04174 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
GKFLCFJD_04176 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
GKFLCFJD_04177 1.77e-314 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKFLCFJD_04178 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
GKFLCFJD_04180 4.33e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GKFLCFJD_04181 3.66e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
GKFLCFJD_04182 1.21e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKFLCFJD_04183 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
GKFLCFJD_04184 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
GKFLCFJD_04185 1.29e-177 yxbB - - Q - - - Met-10+ like-protein
GKFLCFJD_04186 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
GKFLCFJD_04187 8.99e-114 yxnB - - - - - - -
GKFLCFJD_04188 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GKFLCFJD_04189 1.8e-271 yxaM - - U - - - MFS_1 like family
GKFLCFJD_04190 2.63e-137 yxaL - - S - - - PQQ-like domain
GKFLCFJD_04191 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
GKFLCFJD_04192 2.83e-99 yxaI - - S - - - membrane protein domain
GKFLCFJD_04193 2.88e-290 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
GKFLCFJD_04194 9.33e-254 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
GKFLCFJD_04195 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
GKFLCFJD_04196 4.48e-257 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GKFLCFJD_04197 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKFLCFJD_04198 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
GKFLCFJD_04199 2.19e-153 yxaC - - M - - - effector of murein hydrolase
GKFLCFJD_04200 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
GKFLCFJD_04201 2.54e-267 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GKFLCFJD_04202 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
GKFLCFJD_04203 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GKFLCFJD_04204 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
GKFLCFJD_04205 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKFLCFJD_04206 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
GKFLCFJD_04207 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
GKFLCFJD_04208 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKFLCFJD_04209 1.2e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKFLCFJD_04210 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
GKFLCFJD_04211 1.44e-24 - - - - - - - -
GKFLCFJD_04212 4.04e-154 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GKFLCFJD_04213 5.06e-144 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKFLCFJD_04214 1.55e-173 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
GKFLCFJD_04215 1.35e-237 - - - S - - - Radical SAM superfamily
GKFLCFJD_04216 1.99e-17 - - - - - - - -
GKFLCFJD_04217 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
GKFLCFJD_04218 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
GKFLCFJD_04219 7.17e-86 - - - - - - - -
GKFLCFJD_04220 0.0 - - - S - - - Calcineurin-like phosphoesterase
GKFLCFJD_04221 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKFLCFJD_04223 1.25e-93 - - - - - - - -
GKFLCFJD_04224 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GKFLCFJD_04226 1.7e-45 yycQ - - S - - - Protein of unknown function (DUF2651)
GKFLCFJD_04227 1.77e-281 yycP - - - - - - -
GKFLCFJD_04228 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GKFLCFJD_04229 3.84e-113 yycN - - K - - - Acetyltransferase
GKFLCFJD_04230 3.03e-239 - - - S - - - aspartate phosphatase
GKFLCFJD_04232 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
GKFLCFJD_04233 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKFLCFJD_04234 1.5e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
GKFLCFJD_04235 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
GKFLCFJD_04236 2.42e-281 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKFLCFJD_04237 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
GKFLCFJD_04238 1.2e-200 yycI - - S - - - protein conserved in bacteria
GKFLCFJD_04239 0.0 yycH - - S - - - protein conserved in bacteria
GKFLCFJD_04240 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKFLCFJD_04241 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKFLCFJD_04246 6.38e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKFLCFJD_04247 1.19e-101 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKFLCFJD_04248 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GKFLCFJD_04249 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
GKFLCFJD_04251 1.89e-22 yycC - - K - - - YycC-like protein
GKFLCFJD_04252 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
GKFLCFJD_04253 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKFLCFJD_04254 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GKFLCFJD_04255 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GKFLCFJD_04256 5.23e-205 yybS - - S - - - membrane
GKFLCFJD_04258 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
GKFLCFJD_04259 6.68e-90 yybR - - K - - - Transcriptional regulator
GKFLCFJD_04260 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
GKFLCFJD_04261 2.34e-92 - - - - - - - -
GKFLCFJD_04263 6.8e-308 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_04264 3.44e-22 - - - - - - - -
GKFLCFJD_04265 1.61e-102 yybN - - S - - - Protein of unknown function (DUF2712)
GKFLCFJD_04266 3.78e-169 - - - - - - - -
GKFLCFJD_04267 5.36e-157 - - - - - - - -
GKFLCFJD_04268 2.34e-163 - - - S - - - Protein of unknown function (DUF2705)
GKFLCFJD_04269 1.14e-149 yybJ - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKFLCFJD_04270 4.35e-194 - - - - - - - -
GKFLCFJD_04271 3.02e-88 - - - S - - - SnoaL-like domain
GKFLCFJD_04272 1.46e-164 yybG - - S - - - Pentapeptide repeat-containing protein
GKFLCFJD_04273 3.31e-281 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_04274 1.36e-212 yybE - - K - - - Transcriptional regulator
GKFLCFJD_04275 7.91e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
GKFLCFJD_04276 1.27e-99 yybC - - - - - - -
GKFLCFJD_04277 5.29e-165 - - - S - - - Metallo-beta-lactamase superfamily
GKFLCFJD_04278 4.54e-100 yybA - - K - - - transcriptional
GKFLCFJD_04279 2.45e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
GKFLCFJD_04280 8.73e-132 yyaS - - S ko:K07149 - ko00000 Membrane
GKFLCFJD_04281 4.03e-130 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
GKFLCFJD_04282 1.09e-87 - - - S - - - YjbR
GKFLCFJD_04283 2.2e-139 yyaP - - H - - - RibD C-terminal domain
GKFLCFJD_04284 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
GKFLCFJD_04285 1.46e-58 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
GKFLCFJD_04286 1.34e-88 - - - K - - - MerR HTH family regulatory protein
GKFLCFJD_04287 1.99e-207 - - - EG - - - EamA-like transporter family
GKFLCFJD_04288 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
GKFLCFJD_04289 8.91e-217 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKFLCFJD_04290 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
GKFLCFJD_04291 1.14e-130 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
GKFLCFJD_04292 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKFLCFJD_04293 3.03e-230 ccpB - - K - - - Transcriptional regulator
GKFLCFJD_04294 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GKFLCFJD_04295 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKFLCFJD_04296 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKFLCFJD_04297 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GKFLCFJD_04298 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKFLCFJD_04299 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKFLCFJD_04300 7.41e-45 yyzM - - S - - - protein conserved in bacteria
GKFLCFJD_04301 5.34e-227 yyaD - - S - - - Membrane
GKFLCFJD_04302 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
GKFLCFJD_04303 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GKFLCFJD_04304 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
GKFLCFJD_04305 1.13e-98 - - - S - - - Bacterial PH domain
GKFLCFJD_04306 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
GKFLCFJD_04307 8.68e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
GKFLCFJD_04308 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKFLCFJD_04309 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKFLCFJD_04310 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
GKFLCFJD_04311 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKFLCFJD_04312 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)