ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MEAEOFIB_00006 2.91e-25 - - - K - - - Bacterial regulatory proteins, tetR family
MEAEOFIB_00007 5.89e-20 ebrB - - U ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MEAEOFIB_00008 1.13e-181 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MEAEOFIB_00009 1.11e-145 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MEAEOFIB_00010 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MEAEOFIB_00011 2.56e-145 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEAEOFIB_00012 5.96e-206 - - - O - - - Uncharacterized protein family (UPF0051)
MEAEOFIB_00013 1.85e-301 - - - F ko:K03458 - ko00000 Permease
MEAEOFIB_00014 3.23e-251 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
MEAEOFIB_00016 1.33e-91 - - - M - - - LysM domain protein
MEAEOFIB_00017 3.6e-112 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
MEAEOFIB_00018 2.68e-100 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MEAEOFIB_00019 5.29e-61 - - - K - - - Transcriptional regulator, TetR family
MEAEOFIB_00020 1.91e-74 - - - K - - - Transcriptional regulator, TetR family
MEAEOFIB_00023 3.91e-31 - - - - - - - -
MEAEOFIB_00024 1.92e-315 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEAEOFIB_00025 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MEAEOFIB_00026 0.0 - - - EGP - - - Major Facilitator
MEAEOFIB_00027 2.7e-126 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MEAEOFIB_00028 4.58e-64 - - - - - - - -
MEAEOFIB_00029 8.9e-270 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEAEOFIB_00030 1.87e-180 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEAEOFIB_00031 1.99e-282 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEAEOFIB_00032 5.07e-164 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MEAEOFIB_00033 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MEAEOFIB_00034 6.7e-55 - - - - - - - -
MEAEOFIB_00035 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MEAEOFIB_00036 3.19e-79 - - - S - - - Domain of unknown function DUF302
MEAEOFIB_00037 1.98e-200 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEAEOFIB_00038 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MEAEOFIB_00039 4.06e-113 - - - T - - - Belongs to the universal stress protein A family
MEAEOFIB_00040 0.0 - - - S - - - Putative peptidoglycan binding domain
MEAEOFIB_00041 1.89e-239 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEAEOFIB_00042 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
MEAEOFIB_00043 1.21e-143 - - - - - - - -
MEAEOFIB_00044 6.39e-235 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MEAEOFIB_00045 9.66e-151 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEAEOFIB_00046 2.44e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEAEOFIB_00047 1.07e-120 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MEAEOFIB_00048 1.54e-131 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
MEAEOFIB_00049 1.86e-305 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MEAEOFIB_00050 2.08e-132 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
MEAEOFIB_00051 7.02e-256 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
MEAEOFIB_00053 3.12e-49 - - - - - - - -
MEAEOFIB_00055 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MEAEOFIB_00056 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MEAEOFIB_00057 3.95e-73 yheA - - S - - - Belongs to the UPF0342 family
MEAEOFIB_00058 2.9e-227 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEAEOFIB_00059 3.85e-191 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEAEOFIB_00061 4.29e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MEAEOFIB_00062 3.68e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_00063 6.32e-274 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MEAEOFIB_00064 9.51e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEAEOFIB_00065 6.83e-76 - - - S - - - Small secreted protein
MEAEOFIB_00066 4.38e-72 ytpP - - CO - - - Thioredoxin
MEAEOFIB_00067 1.3e-151 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEAEOFIB_00068 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MEAEOFIB_00069 1.24e-146 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MEAEOFIB_00070 6.62e-178 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
MEAEOFIB_00071 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEAEOFIB_00072 7.57e-208 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEAEOFIB_00073 1.14e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEAEOFIB_00074 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEAEOFIB_00075 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MEAEOFIB_00076 2.66e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MEAEOFIB_00077 6.95e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEAEOFIB_00078 5.22e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MEAEOFIB_00079 4.67e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEAEOFIB_00080 6.74e-31 - - - S - - - Protein of unknown function (DUF1275)
MEAEOFIB_00081 4.65e-123 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MEAEOFIB_00082 1.88e-274 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MEAEOFIB_00083 1.38e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MEAEOFIB_00084 6.58e-120 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEAEOFIB_00085 5.53e-145 yqeK - - H - - - Hydrolase, HD family
MEAEOFIB_00086 2.79e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEAEOFIB_00087 1.49e-174 yqeM - - Q - - - Methyltransferase
MEAEOFIB_00088 1.6e-271 ylbM - - S - - - Belongs to the UPF0348 family
MEAEOFIB_00089 2.79e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MEAEOFIB_00090 7.89e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MEAEOFIB_00091 5.62e-155 csrR - - K - - - response regulator
MEAEOFIB_00092 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEAEOFIB_00093 4.43e-297 - - - V - - - MatE
MEAEOFIB_00094 1.85e-90 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEAEOFIB_00095 1.43e-199 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEAEOFIB_00096 8.13e-62 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MEAEOFIB_00097 1.51e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEAEOFIB_00098 4.08e-117 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEAEOFIB_00099 1.44e-78 yodB - - K - - - Transcriptional regulator, HxlR family
MEAEOFIB_00100 1.74e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEAEOFIB_00101 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEAEOFIB_00102 2.93e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MEAEOFIB_00103 5.2e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEAEOFIB_00104 0.0 - - - S - - - membrane
MEAEOFIB_00105 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MEAEOFIB_00106 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MEAEOFIB_00107 4.45e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEAEOFIB_00108 5.16e-136 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MEAEOFIB_00109 1.14e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MEAEOFIB_00110 4.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MEAEOFIB_00111 5.91e-93 yqhL - - P - - - Rhodanese-like protein
MEAEOFIB_00112 3.51e-33 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MEAEOFIB_00113 4.25e-219 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEAEOFIB_00114 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MEAEOFIB_00115 4.76e-19 - - - - - - - -
MEAEOFIB_00116 2.59e-199 - - - - - - - -
MEAEOFIB_00117 5.51e-225 - - - - - - - -
MEAEOFIB_00118 1.1e-120 - - - S - - - Protein conserved in bacteria
MEAEOFIB_00120 2.14e-147 - - - K - - - Transcriptional regulator
MEAEOFIB_00121 1.89e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MEAEOFIB_00122 1.2e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MEAEOFIB_00123 8.74e-62 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MEAEOFIB_00124 1.2e-262 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MEAEOFIB_00125 2.1e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MEAEOFIB_00126 2.71e-89 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEAEOFIB_00127 1.16e-205 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEAEOFIB_00128 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEAEOFIB_00129 4.68e-25 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEAEOFIB_00130 2.41e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEAEOFIB_00131 2.69e-188 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MEAEOFIB_00132 4.92e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MEAEOFIB_00133 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MEAEOFIB_00135 4.19e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MEAEOFIB_00136 1.9e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEAEOFIB_00137 3.29e-279 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEAEOFIB_00138 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEAEOFIB_00139 1.09e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEAEOFIB_00140 1.29e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEAEOFIB_00141 6.83e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MEAEOFIB_00142 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MEAEOFIB_00143 9.22e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEAEOFIB_00144 1.75e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MEAEOFIB_00145 5.28e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MEAEOFIB_00146 1e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MEAEOFIB_00147 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
MEAEOFIB_00148 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MEAEOFIB_00149 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEAEOFIB_00150 4.44e-215 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEAEOFIB_00151 1.65e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEAEOFIB_00152 3.99e-166 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEAEOFIB_00153 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MEAEOFIB_00154 7.66e-287 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEAEOFIB_00155 4.94e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEAEOFIB_00156 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEAEOFIB_00158 4.26e-132 - - - - - - - -
MEAEOFIB_00159 1.24e-170 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
MEAEOFIB_00160 1.63e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MEAEOFIB_00161 1.95e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MEAEOFIB_00162 1.74e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MEAEOFIB_00163 1.33e-174 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEAEOFIB_00164 2.78e-158 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MEAEOFIB_00165 4.94e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MEAEOFIB_00166 1.07e-52 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MEAEOFIB_00167 1.78e-113 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEAEOFIB_00168 2.22e-182 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MEAEOFIB_00169 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MEAEOFIB_00170 6.59e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEAEOFIB_00171 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase cas3
MEAEOFIB_00172 2.73e-177 casA - - L ko:K19123 - ko00000,ko02048 the current gene model (or a revised gene model) may contain a frame shift
MEAEOFIB_00173 1.12e-51 - - - S ko:K19046 - ko00000,ko02048 CRISPR-associated protein Cse2 (CRISPR_cse2)
MEAEOFIB_00174 7.76e-164 casC - - L ko:K19124 - ko00000,ko02048 CT1975-like protein
MEAEOFIB_00175 3.28e-81 casD - - S ko:K19125 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
MEAEOFIB_00176 2.37e-90 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
MEAEOFIB_00177 1.46e-158 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEAEOFIB_00178 1.04e-100 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas2CT1978)
MEAEOFIB_00181 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEAEOFIB_00182 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MEAEOFIB_00183 1.86e-218 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEAEOFIB_00184 8.55e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MEAEOFIB_00185 2.47e-85 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
MEAEOFIB_00186 4.94e-88 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
MEAEOFIB_00187 2.08e-239 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEAEOFIB_00188 1.66e-217 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
MEAEOFIB_00189 1.64e-303 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
MEAEOFIB_00190 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MEAEOFIB_00191 4.27e-275 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MEAEOFIB_00192 5.78e-268 arcT - - E - - - Aminotransferase
MEAEOFIB_00193 3.25e-166 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MEAEOFIB_00194 4.38e-140 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MEAEOFIB_00195 2.87e-247 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEAEOFIB_00197 3.83e-100 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEAEOFIB_00198 8.9e-96 - - - K - - - Transcriptional regulator, MarR family
MEAEOFIB_00199 1.53e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEAEOFIB_00200 4.18e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEAEOFIB_00201 1.86e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MEAEOFIB_00202 7.65e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MEAEOFIB_00203 1.32e-291 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEAEOFIB_00204 3.46e-94 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEAEOFIB_00205 1.13e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEAEOFIB_00206 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MEAEOFIB_00207 7.54e-205 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEAEOFIB_00208 1.1e-180 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MEAEOFIB_00209 1.27e-173 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MEAEOFIB_00210 3.1e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MEAEOFIB_00211 2.02e-222 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEAEOFIB_00212 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MEAEOFIB_00213 1.9e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEAEOFIB_00214 1.15e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEAEOFIB_00215 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEAEOFIB_00216 0.0 ydaO - - E - - - amino acid
MEAEOFIB_00217 4.12e-50 - - - - - - - -
MEAEOFIB_00218 4e-147 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MEAEOFIB_00219 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MEAEOFIB_00220 2.07e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MEAEOFIB_00221 4.64e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEAEOFIB_00222 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEAEOFIB_00223 1.24e-258 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEAEOFIB_00224 5.66e-70 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
MEAEOFIB_00225 4.15e-69 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MEAEOFIB_00226 6.56e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEAEOFIB_00227 7.58e-209 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEAEOFIB_00228 8.71e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MEAEOFIB_00229 7.64e-220 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MEAEOFIB_00230 1.06e-188 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MEAEOFIB_00231 1.03e-287 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MEAEOFIB_00232 6.21e-241 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEAEOFIB_00233 6.36e-74 yphH - - S - - - Cupin domain
MEAEOFIB_00234 4.74e-166 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEAEOFIB_00235 9.46e-198 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MEAEOFIB_00236 7.3e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MEAEOFIB_00237 1.85e-179 - - - L - - - PFAM Integrase catalytic region
MEAEOFIB_00238 5.62e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MEAEOFIB_00239 1.59e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MEAEOFIB_00240 1.99e-174 - - - S - - - haloacid dehalogenase-like hydrolase
MEAEOFIB_00241 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MEAEOFIB_00242 1.24e-145 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MEAEOFIB_00244 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEAEOFIB_00245 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEAEOFIB_00246 1.7e-259 - - - - - - - -
MEAEOFIB_00247 9.14e-205 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MEAEOFIB_00248 2e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MEAEOFIB_00249 5.51e-213 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MEAEOFIB_00250 4.39e-100 - 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MEAEOFIB_00251 2.96e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEAEOFIB_00252 6.7e-115 - - - L ko:K07497 - ko00000 hmm pf00665
MEAEOFIB_00253 6.81e-123 - - - M - - - PFAM NLP P60 protein
MEAEOFIB_00254 5.01e-172 yebC - - K - - - Transcriptional regulatory protein
MEAEOFIB_00255 6.65e-180 - - - - - - - -
MEAEOFIB_00256 9.84e-237 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MEAEOFIB_00257 1.8e-271 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MEAEOFIB_00258 4.44e-90 - - - - - - - -
MEAEOFIB_00259 5.14e-68 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MEAEOFIB_00260 8.71e-200 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MEAEOFIB_00261 6.84e-191 - - - S - - - haloacid dehalogenase-like hydrolase
MEAEOFIB_00262 2.25e-121 - - - S ko:K07095 - ko00000 Phosphoesterase
MEAEOFIB_00263 3.09e-139 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEAEOFIB_00264 1.83e-189 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MEAEOFIB_00265 1.96e-120 yslB - - S - - - Protein of unknown function (DUF2507)
MEAEOFIB_00266 3.59e-284 - - - P - - - Chloride transporter, ClC family
MEAEOFIB_00267 1.66e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEAEOFIB_00268 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEAEOFIB_00269 6.39e-119 cvpA - - S - - - Colicin V production protein
MEAEOFIB_00270 1.25e-208 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEAEOFIB_00271 3.99e-55 yrzB - - S - - - Belongs to the UPF0473 family
MEAEOFIB_00272 8.26e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEAEOFIB_00273 1.06e-57 yrzL - - S - - - Belongs to the UPF0297 family
MEAEOFIB_00274 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEAEOFIB_00275 2.82e-299 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEAEOFIB_00276 4.44e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MEAEOFIB_00277 2.77e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MEAEOFIB_00278 6.26e-226 - 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 queuine tRNA-ribosyltransferase activity
MEAEOFIB_00279 9.91e-241 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEAEOFIB_00280 8.79e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEAEOFIB_00281 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEAEOFIB_00282 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEAEOFIB_00283 6.87e-300 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MEAEOFIB_00284 2.68e-244 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEAEOFIB_00285 2.68e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MEAEOFIB_00286 2.97e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEAEOFIB_00287 1.64e-151 - - - S - - - Helix-turn-helix domain
MEAEOFIB_00288 2.5e-315 ymfH - - S - - - Peptidase M16
MEAEOFIB_00289 1.91e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
MEAEOFIB_00290 1.58e-203 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MEAEOFIB_00291 2.81e-148 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_00292 3.81e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MEAEOFIB_00293 9.04e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MEAEOFIB_00294 1.95e-187 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MEAEOFIB_00295 1.56e-231 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MEAEOFIB_00296 5.3e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
MEAEOFIB_00297 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MEAEOFIB_00298 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEAEOFIB_00299 3.11e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEAEOFIB_00302 9.23e-97 - - - L ko:K07497 - ko00000 hmm pf00665
MEAEOFIB_00303 7.28e-165 - - - L - - - Helix-turn-helix domain
MEAEOFIB_00304 6.82e-42 - - - S - - - zinc-ribbon domain
MEAEOFIB_00305 3.22e-52 - - - - - - - -
MEAEOFIB_00309 1.99e-39 - - - M - - - LysM domain
MEAEOFIB_00310 1.29e-259 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MEAEOFIB_00311 3.24e-277 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
MEAEOFIB_00312 1.13e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEAEOFIB_00313 8.29e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MEAEOFIB_00314 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEAEOFIB_00315 5.1e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEAEOFIB_00318 7.66e-35 - - - S - - - YjcQ protein
MEAEOFIB_00319 6.07e-190 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEAEOFIB_00320 6.58e-173 - - - S - - - Membrane
MEAEOFIB_00321 1.52e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
MEAEOFIB_00322 8.04e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MEAEOFIB_00323 6.16e-299 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MEAEOFIB_00325 3.52e-106 uspA - - T - - - universal stress protein
MEAEOFIB_00326 2.95e-202 - - - K - - - Helix-turn-helix XRE-family like proteins
MEAEOFIB_00327 8.08e-205 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MEAEOFIB_00328 2.06e-157 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
MEAEOFIB_00329 3.61e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MEAEOFIB_00330 2.73e-161 - - - S - - - Putative threonine/serine exporter
MEAEOFIB_00331 2.34e-106 - - - S - - - Threonine/Serine exporter, ThrE
MEAEOFIB_00332 3e-147 - - - I - - - phosphatase
MEAEOFIB_00333 6.96e-199 - - - I - - - alpha/beta hydrolase fold
MEAEOFIB_00335 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MEAEOFIB_00336 5.48e-150 dgk2 - - F - - - deoxynucleoside kinase
MEAEOFIB_00342 1.13e-66 - - - IQ - - - reductase
MEAEOFIB_00343 5.48e-20 - - - IQ - - - reductase
MEAEOFIB_00344 4.82e-189 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEAEOFIB_00345 1.84e-66 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MEAEOFIB_00346 2.42e-90 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
MEAEOFIB_00347 1.26e-46 rmeB - - K - - - transcriptional regulator, MerR family
MEAEOFIB_00348 5.54e-42 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Hexapeptide repeat of succinyl-transferase
MEAEOFIB_00349 1.49e-154 - - - J - - - 2'-5' RNA ligase superfamily
MEAEOFIB_00350 1.69e-170 XK27_07210 - - S - - - B3 4 domain
MEAEOFIB_00351 2.76e-247 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEAEOFIB_00352 6.36e-103 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MEAEOFIB_00353 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEAEOFIB_00354 2.44e-136 - - - K - - - Bacterial regulatory proteins, tetR family
MEAEOFIB_00355 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAEOFIB_00356 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAEOFIB_00357 2.92e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MEAEOFIB_00358 3.02e-275 - - - - - - - -
MEAEOFIB_00359 2.5e-40 pilD 3.4.23.43 - NOU ko:K02236,ko:K02506,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 aspartic-type endopeptidase activity
MEAEOFIB_00360 3.58e-93 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEAEOFIB_00361 4.15e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEAEOFIB_00362 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEAEOFIB_00363 3.14e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MEAEOFIB_00364 5.89e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEAEOFIB_00365 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MEAEOFIB_00366 2.76e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEAEOFIB_00367 1.92e-202 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEAEOFIB_00368 1.51e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEAEOFIB_00369 2.63e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEAEOFIB_00370 3.43e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEAEOFIB_00371 2.78e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEAEOFIB_00372 1.35e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MEAEOFIB_00373 4.48e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEAEOFIB_00374 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEAEOFIB_00375 1.28e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEAEOFIB_00376 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEAEOFIB_00377 2.46e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEAEOFIB_00378 7.64e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEAEOFIB_00379 2.05e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEAEOFIB_00380 5.55e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEAEOFIB_00381 2.43e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEAEOFIB_00382 6.96e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MEAEOFIB_00383 3.5e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MEAEOFIB_00384 1.36e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEAEOFIB_00385 1.78e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEAEOFIB_00386 1.69e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEAEOFIB_00387 2.6e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MEAEOFIB_00388 1.32e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEAEOFIB_00389 8.02e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEAEOFIB_00390 9.96e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAEOFIB_00391 1.02e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MEAEOFIB_00392 1.75e-192 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAEOFIB_00393 2.06e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAEOFIB_00394 2.37e-178 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAEOFIB_00395 7.76e-186 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEAEOFIB_00396 5.57e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEAEOFIB_00397 3.24e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MEAEOFIB_00398 2.71e-259 - - - S - - - interspecies interaction between organisms
MEAEOFIB_00399 4.28e-178 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
MEAEOFIB_00400 2.33e-142 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MEAEOFIB_00401 9.17e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEAEOFIB_00402 1.02e-277 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEAEOFIB_00403 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MEAEOFIB_00404 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEAEOFIB_00405 2.26e-232 camS - - S - - - sex pheromone
MEAEOFIB_00406 9.93e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEAEOFIB_00407 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEAEOFIB_00408 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEAEOFIB_00409 8.8e-238 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MEAEOFIB_00410 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEAEOFIB_00412 1.02e-39 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_00413 6.71e-241 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEAEOFIB_00414 2.3e-26 - - - D ko:K06889 - ko00000 Alpha beta
MEAEOFIB_00415 2.61e-36 - - - D ko:K06889 - ko00000 Alpha beta
MEAEOFIB_00416 2.4e-232 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_00417 3.82e-275 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MEAEOFIB_00418 3.88e-46 - - - - - - - -
MEAEOFIB_00419 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
MEAEOFIB_00420 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEAEOFIB_00421 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MEAEOFIB_00422 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MEAEOFIB_00423 5.13e-210 - - - C - - - Aldo keto reductase
MEAEOFIB_00424 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MEAEOFIB_00425 2.13e-85 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MEAEOFIB_00426 2.67e-236 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MEAEOFIB_00427 3.63e-163 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MEAEOFIB_00428 2.51e-119 - - - K - - - transcriptional regulator
MEAEOFIB_00429 1.63e-211 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEAEOFIB_00430 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEAEOFIB_00431 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MEAEOFIB_00432 8.04e-124 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEAEOFIB_00433 5.85e-169 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEAEOFIB_00434 4.18e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEAEOFIB_00435 3.97e-62 - - - - - - - -
MEAEOFIB_00436 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEAEOFIB_00437 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
MEAEOFIB_00438 2.49e-193 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MEAEOFIB_00439 1.92e-241 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEAEOFIB_00440 2.89e-139 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEAEOFIB_00441 5.22e-276 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MEAEOFIB_00442 1.97e-312 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEAEOFIB_00443 2.29e-249 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MEAEOFIB_00444 7.63e-155 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MEAEOFIB_00445 8.89e-306 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEAEOFIB_00446 3.78e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEAEOFIB_00447 1.07e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MEAEOFIB_00448 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEAEOFIB_00449 9.8e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MEAEOFIB_00450 8.66e-277 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEAEOFIB_00451 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MEAEOFIB_00452 3.66e-315 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEAEOFIB_00454 9.49e-238 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MEAEOFIB_00456 6.29e-285 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEAEOFIB_00457 1.28e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_00458 2.68e-127 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
MEAEOFIB_00459 9.6e-199 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
MEAEOFIB_00460 2.53e-142 - - - K - - - Helix-turn-helix domain
MEAEOFIB_00461 8.18e-80 - - - S ko:K07090 - ko00000 membrane transporter protein
MEAEOFIB_00462 5.47e-53 nreC - - K - - - helix_turn_helix, Lux Regulon
MEAEOFIB_00463 9.84e-95 - - - S - - - Bacterial transferase hexapeptide (six repeats)
MEAEOFIB_00464 2.34e-151 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MEAEOFIB_00465 1.01e-252 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
MEAEOFIB_00466 2.17e-11 - - - K - - - transcriptional
MEAEOFIB_00467 1.56e-67 - - - S - - - Sugar efflux transporter for intercellular exchange
MEAEOFIB_00468 4.62e-35 - - - S - - - Antibiotic biosynthesis monooxygenase
MEAEOFIB_00469 1.97e-57 - - - S - - - Protein conserved in bacteria
MEAEOFIB_00470 1.38e-99 ydeQ - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
MEAEOFIB_00471 3.54e-57 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MEAEOFIB_00472 1.06e-193 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
MEAEOFIB_00473 4.53e-238 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_00474 2.84e-82 - - - S - - - Domain of unknown function (DUF4440)
MEAEOFIB_00475 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEAEOFIB_00476 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MEAEOFIB_00477 1.3e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MEAEOFIB_00478 8.64e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEAEOFIB_00479 5.73e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEAEOFIB_00480 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEAEOFIB_00481 2.68e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_00483 5.48e-70 - - - S - - - mazG nucleotide pyrophosphohydrolase
MEAEOFIB_00484 4.39e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MEAEOFIB_00485 4.84e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEAEOFIB_00486 5.48e-298 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEAEOFIB_00487 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEAEOFIB_00488 6.1e-204 - - - S - - - Tetratricopeptide repeat
MEAEOFIB_00489 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEAEOFIB_00490 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MEAEOFIB_00491 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEAEOFIB_00492 5.85e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MEAEOFIB_00493 7.75e-235 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MEAEOFIB_00494 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MEAEOFIB_00495 2.48e-115 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MEAEOFIB_00496 1.47e-127 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MEAEOFIB_00497 2.29e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MEAEOFIB_00498 2.51e-115 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEAEOFIB_00499 1.49e-127 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MEAEOFIB_00500 1.31e-63 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MEAEOFIB_00501 1.8e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MEAEOFIB_00502 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MEAEOFIB_00503 1.96e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MEAEOFIB_00504 1.55e-65 yktA - - S - - - Belongs to the UPF0223 family
MEAEOFIB_00505 8.59e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEAEOFIB_00506 6.12e-98 - - - - - - - -
MEAEOFIB_00507 8.83e-43 ykzG - - S - - - Belongs to the UPF0356 family
MEAEOFIB_00508 2.42e-238 - - - I - - - Diacylglycerol kinase catalytic
MEAEOFIB_00509 2.39e-98 - - - P - - - ArsC family
MEAEOFIB_00510 5.44e-139 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MEAEOFIB_00511 7.3e-121 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEAEOFIB_00512 8.83e-243 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEAEOFIB_00513 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_00514 4.37e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEAEOFIB_00515 1.66e-198 - - - L - - - Phage integrase, N-terminal SAM-like domain
MEAEOFIB_00516 1.15e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MEAEOFIB_00517 2.65e-53 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEAEOFIB_00518 1.83e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MEAEOFIB_00519 2.67e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MEAEOFIB_00520 2.58e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MEAEOFIB_00521 2.94e-70 - - - M - - - Lysin motif
MEAEOFIB_00522 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MEAEOFIB_00523 4.28e-251 - - - S - - - Helix-turn-helix domain
MEAEOFIB_00524 8.28e-112 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEAEOFIB_00525 1.68e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MEAEOFIB_00526 1.85e-130 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEAEOFIB_00527 1.18e-182 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEAEOFIB_00528 3.7e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEAEOFIB_00529 2.84e-173 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MEAEOFIB_00530 6.26e-215 yitL - - S ko:K00243 - ko00000 S1 domain
MEAEOFIB_00531 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MEAEOFIB_00532 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MEAEOFIB_00534 2.52e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MEAEOFIB_00535 1.2e-201 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEAEOFIB_00536 1.33e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MEAEOFIB_00537 5.64e-153 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MEAEOFIB_00538 1.38e-292 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MEAEOFIB_00539 1.05e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEAEOFIB_00540 2.69e-275 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MEAEOFIB_00541 7.4e-180 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEAEOFIB_00542 8.59e-221 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEAEOFIB_00543 1.56e-278 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEAEOFIB_00544 3.68e-114 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEAEOFIB_00545 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEAEOFIB_00546 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MEAEOFIB_00547 5.87e-231 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEAEOFIB_00548 4.36e-210 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEAEOFIB_00549 8.63e-32 - - - EGP - - - Major Facilitator
MEAEOFIB_00550 8.48e-68 - - - EGP - - - Major Facilitator
MEAEOFIB_00565 1.12e-90 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEAEOFIB_00566 2.53e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MEAEOFIB_00567 9.03e-258 coiA - - S ko:K06198 - ko00000 Competence protein
MEAEOFIB_00568 5.71e-145 yjbH - - Q - - - Thioredoxin
MEAEOFIB_00569 3.03e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MEAEOFIB_00570 9.49e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEAEOFIB_00571 1.55e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEAEOFIB_00572 1.73e-247 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MEAEOFIB_00573 3.74e-206 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MEAEOFIB_00574 5.55e-121 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEAEOFIB_00575 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MEAEOFIB_00576 4.5e-12 - - - S - - - Protein of unknown function (DUF4044)
MEAEOFIB_00577 9.82e-76 - - - - - - - -
MEAEOFIB_00578 7.65e-104 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MEAEOFIB_00579 5.37e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEAEOFIB_00580 4.29e-30 ftsL - - D - - - Cell division protein FtsL
MEAEOFIB_00581 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MEAEOFIB_00582 1.56e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEAEOFIB_00583 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEAEOFIB_00584 1.39e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEAEOFIB_00585 9.64e-187 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEAEOFIB_00586 8.07e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEAEOFIB_00587 4.09e-287 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEAEOFIB_00588 1.5e-101 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEAEOFIB_00589 7.27e-56 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MEAEOFIB_00590 2.49e-186 ylmH - - S - - - S4 domain protein
MEAEOFIB_00591 4.17e-141 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MEAEOFIB_00593 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEAEOFIB_00594 9.99e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MEAEOFIB_00595 2.12e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MEAEOFIB_00596 9.41e-09 - - - - - - - -
MEAEOFIB_00597 3.8e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEAEOFIB_00598 7.86e-77 XK27_04120 - - S - - - Putative amino acid metabolism
MEAEOFIB_00599 1.98e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEAEOFIB_00600 0.0 - - - S - - - amidohydrolase
MEAEOFIB_00601 1.26e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MEAEOFIB_00602 1.11e-156 pgm6 - - G - - - phosphoglycerate mutase
MEAEOFIB_00603 9.37e-159 - - - S - - - repeat protein
MEAEOFIB_00604 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEAEOFIB_00605 3.65e-226 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEAEOFIB_00606 3.82e-23 - - - - - - - -
MEAEOFIB_00607 1.31e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEAEOFIB_00608 4.22e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MEAEOFIB_00609 1.39e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEAEOFIB_00610 9.45e-317 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEAEOFIB_00611 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MEAEOFIB_00612 0.0 eriC - - P ko:K03281 - ko00000 chloride
MEAEOFIB_00613 6.82e-46 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MEAEOFIB_00614 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEAEOFIB_00615 1.9e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEAEOFIB_00616 1.36e-138 - - - - - - - -
MEAEOFIB_00617 2.15e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEAEOFIB_00618 9.74e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MEAEOFIB_00619 4.21e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MEAEOFIB_00620 1.7e-112 - - - K - - - Acetyltransferase (GNAT) domain
MEAEOFIB_00621 4e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MEAEOFIB_00622 4.72e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MEAEOFIB_00623 2.67e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEAEOFIB_00624 6.88e-151 ybbR - - S - - - YbbR-like protein
MEAEOFIB_00625 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEAEOFIB_00626 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEAEOFIB_00627 2.55e-68 - - - - - - - -
MEAEOFIB_00628 2.04e-263 oatA - - I - - - Acyltransferase
MEAEOFIB_00629 5.01e-192 XK27_02985 - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEAEOFIB_00630 1.85e-110 lytE - - M - - - Lysin motif
MEAEOFIB_00631 6.96e-222 - - - S - - - Conserved hypothetical protein 698
MEAEOFIB_00632 2.86e-214 - - - K - - - LysR substrate binding domain
MEAEOFIB_00633 6.68e-165 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MEAEOFIB_00634 4.28e-189 yitS - - S - - - EDD domain protein, DegV family
MEAEOFIB_00635 3.43e-114 - - - K - - - Domain of unknown function (DUF1836)
MEAEOFIB_00636 8.71e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MEAEOFIB_00637 1.28e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MEAEOFIB_00638 3.38e-164 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MEAEOFIB_00639 6.52e-218 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MEAEOFIB_00640 8.58e-75 manO - - S - - - Domain of unknown function (DUF956)
MEAEOFIB_00643 1.01e-141 ycsI - - S - - - Protein of unknown function (DUF1445)
MEAEOFIB_00644 4.65e-230 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MEAEOFIB_00645 4.44e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEAEOFIB_00646 6.95e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MEAEOFIB_00647 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MEAEOFIB_00648 3.21e-213 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEAEOFIB_00649 2.17e-61 - - - L ko:K07491 - ko00000 Transposase IS200 like
MEAEOFIB_00650 4.92e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MEAEOFIB_00651 1.25e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MEAEOFIB_00652 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MEAEOFIB_00653 1.33e-115 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MEAEOFIB_00654 1.85e-119 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MEAEOFIB_00655 3.06e-129 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MEAEOFIB_00656 2.62e-118 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEAEOFIB_00657 8.41e-260 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEAEOFIB_00658 3.35e-270 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MEAEOFIB_00659 3.53e-229 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MEAEOFIB_00660 8.83e-214 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MEAEOFIB_00661 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MEAEOFIB_00662 6.4e-113 ypmB - - S - - - Protein conserved in bacteria
MEAEOFIB_00663 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MEAEOFIB_00664 2.4e-172 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MEAEOFIB_00665 5.43e-190 ypuA - - S - - - Protein of unknown function (DUF1002)
MEAEOFIB_00666 2.25e-241 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MEAEOFIB_00667 1.24e-68 - - - EG - - - EamA-like transporter family
MEAEOFIB_00668 8.96e-105 - - - EG - - - EamA-like transporter family
MEAEOFIB_00669 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MEAEOFIB_00670 3.31e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEAEOFIB_00671 1.79e-143 ypsA - - S - - - Belongs to the UPF0398 family
MEAEOFIB_00672 3.46e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEAEOFIB_00673 2.09e-192 - - - K ko:K02538 - ko00000,ko03000 PRD domain
MEAEOFIB_00675 6.64e-73 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEAEOFIB_00676 7.22e-275 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MEAEOFIB_00677 3.27e-49 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MEAEOFIB_00678 4.35e-178 - - - L - - - PFAM Integrase catalytic region
MEAEOFIB_00679 3.25e-202 hpaIIM 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MEAEOFIB_00680 1.78e-193 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MEAEOFIB_00682 1.58e-94 - - - L - - - NgoFVII restriction endonuclease
MEAEOFIB_00683 7.02e-62 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 DNA mismatch endonuclease Vsr
MEAEOFIB_00684 5.87e-174 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEAEOFIB_00685 1.62e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEAEOFIB_00686 3.36e-271 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MEAEOFIB_00687 3.97e-53 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MEAEOFIB_00688 5.59e-250 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MEAEOFIB_00689 8.46e-133 - - - NU - - - mannosyl-glycoprotein
MEAEOFIB_00690 3.44e-122 - - - K - - - Acetyltransferase (GNAT) family
MEAEOFIB_00691 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
MEAEOFIB_00692 4.35e-108 - - - S - - - Psort location Cytoplasmic, score
MEAEOFIB_00693 3.69e-92 - - - K - - - helix_turn_helix, mercury resistance
MEAEOFIB_00694 1.8e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MEAEOFIB_00695 5.77e-244 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MEAEOFIB_00696 1.59e-86 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEAEOFIB_00697 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MEAEOFIB_00698 1.36e-161 - - - S ko:K07160 - ko00000 LamB/YcsF family
MEAEOFIB_00699 4.75e-269 ycsG - - P - - - Natural resistance-associated macrophage protein
MEAEOFIB_00700 1.03e-265 - - - EGP - - - Major Facilitator
MEAEOFIB_00701 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
MEAEOFIB_00702 9.26e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEAEOFIB_00703 1.11e-194 - - - S ko:K07088 - ko00000 Membrane transport protein
MEAEOFIB_00705 1.37e-55 - - - L - - - nuclease
MEAEOFIB_00706 5.96e-207 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MEAEOFIB_00707 1.16e-144 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MEAEOFIB_00708 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEAEOFIB_00709 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEAEOFIB_00710 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MEAEOFIB_00711 5.31e-285 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MEAEOFIB_00712 1.2e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEAEOFIB_00713 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEAEOFIB_00714 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEAEOFIB_00715 4.31e-197 jag - - S ko:K06346 - ko00000 R3H domain protein
MEAEOFIB_00716 4.1e-186 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEAEOFIB_00717 5.32e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEAEOFIB_00718 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MEAEOFIB_00720 1.42e-315 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEAEOFIB_00721 3.2e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEAEOFIB_00722 1.45e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MEAEOFIB_00723 8e-255 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEAEOFIB_00724 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEAEOFIB_00725 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEAEOFIB_00726 6.02e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MEAEOFIB_00727 2.41e-151 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEAEOFIB_00728 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEAEOFIB_00729 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MEAEOFIB_00730 2.16e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MEAEOFIB_00731 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MEAEOFIB_00732 5.13e-267 - - - E - - - Major Facilitator Superfamily
MEAEOFIB_00733 3.34e-77 - - - - - - - -
MEAEOFIB_00734 1.91e-144 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MEAEOFIB_00735 6.31e-172 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MEAEOFIB_00736 2.57e-60 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MEAEOFIB_00737 4.46e-179 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MEAEOFIB_00738 3.4e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEAEOFIB_00739 6.84e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MEAEOFIB_00740 5.35e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEAEOFIB_00741 2.59e-183 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEAEOFIB_00742 6.74e-173 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MEAEOFIB_00743 2.4e-295 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MEAEOFIB_00744 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEAEOFIB_00745 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEAEOFIB_00746 1.55e-273 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
MEAEOFIB_00747 1.14e-173 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MEAEOFIB_00748 4.97e-264 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MEAEOFIB_00749 7.08e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEAEOFIB_00750 1.2e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MEAEOFIB_00751 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MEAEOFIB_00752 1.49e-107 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MEAEOFIB_00753 2.61e-280 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MEAEOFIB_00754 3.71e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MEAEOFIB_00755 5.29e-65 ylxQ - - J - - - ribosomal protein
MEAEOFIB_00756 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEAEOFIB_00757 8.62e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEAEOFIB_00758 9.23e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEAEOFIB_00759 1.33e-229 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MEAEOFIB_00760 3.86e-314 - - - U - - - Belongs to the major facilitator superfamily
MEAEOFIB_00761 1.37e-182 yidA - - S - - - hydrolase
MEAEOFIB_00762 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MEAEOFIB_00763 2.13e-96 ywiB - - S - - - Domain of unknown function (DUF1934)
MEAEOFIB_00764 3.57e-96 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEAEOFIB_00765 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEAEOFIB_00766 8.81e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEAEOFIB_00767 3.85e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MEAEOFIB_00768 3.61e-64 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
MEAEOFIB_00769 3.67e-49 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
MEAEOFIB_00770 5.38e-158 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MEAEOFIB_00771 2.02e-58 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEAEOFIB_00772 6.76e-119 lemA - - S ko:K03744 - ko00000 LemA family
MEAEOFIB_00773 1.9e-202 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MEAEOFIB_00774 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEAEOFIB_00775 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEAEOFIB_00776 1.18e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEAEOFIB_00777 1.79e-267 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEAEOFIB_00778 1.67e-73 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MEAEOFIB_00779 4.51e-148 - - - S - - - (CBS) domain
MEAEOFIB_00780 7.98e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEAEOFIB_00781 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEAEOFIB_00782 2.47e-53 yabO - - J - - - S4 domain protein
MEAEOFIB_00783 5.88e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MEAEOFIB_00784 6.71e-113 yabR - - J ko:K07571 - ko00000 RNA binding
MEAEOFIB_00785 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEAEOFIB_00786 2.67e-123 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MEAEOFIB_00787 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEAEOFIB_00788 3.19e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEAEOFIB_00789 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEAEOFIB_00790 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MEAEOFIB_00791 2.76e-182 - - - EG - - - EamA-like transporter family
MEAEOFIB_00792 0.0 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MEAEOFIB_00793 1.04e-26 - - - S - - - Domain of unknown function (DUF1858)
MEAEOFIB_00794 3.62e-72 yitW - - S - - - Iron-sulfur cluster assembly protein
MEAEOFIB_00795 8.95e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MEAEOFIB_00796 6.12e-182 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MEAEOFIB_00797 1.78e-219 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEAEOFIB_00798 2.87e-76 - - - S - - - Flavodoxin
MEAEOFIB_00799 7.91e-95 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
MEAEOFIB_00800 2.34e-47 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
MEAEOFIB_00801 1.67e-249 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MEAEOFIB_00802 7.73e-277 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Major Facilitator Superfamily
MEAEOFIB_00803 2.36e-77 - - - S - - - Iron-sulfur cluster assembly protein
MEAEOFIB_00804 4.54e-208 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MEAEOFIB_00805 5.05e-172 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MEAEOFIB_00807 3.74e-212 - - - H - - - geranyltranstransferase activity
MEAEOFIB_00808 5.69e-234 - - - - - - - -
MEAEOFIB_00809 1.99e-53 - - - - - - - -
MEAEOFIB_00810 1.06e-149 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
MEAEOFIB_00811 5.67e-240 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
MEAEOFIB_00812 2.47e-101 nreA - - T ko:K10851 ko02020,map02020 ko00000,ko00001 GAF domain
MEAEOFIB_00813 6.94e-54 - - - - - - - -
MEAEOFIB_00814 5.41e-123 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MEAEOFIB_00815 5.39e-106 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MEAEOFIB_00816 1.05e-293 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
MEAEOFIB_00817 2.55e-111 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MEAEOFIB_00818 2.96e-242 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
MEAEOFIB_00819 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEAEOFIB_00820 0.0 - 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
MEAEOFIB_00821 7.2e-131 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
MEAEOFIB_00822 1.24e-163 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
MEAEOFIB_00823 3.05e-235 - - - - - - - -
MEAEOFIB_00824 2.91e-99 - - - - - - - -
MEAEOFIB_00825 4.02e-145 cat 2.3.1.79 - S ko:K00661,ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
MEAEOFIB_00826 5.54e-214 - - - E - - - lipolytic protein G-D-S-L family
MEAEOFIB_00827 2.85e-135 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MEAEOFIB_00828 1.73e-48 yozE - - S - - - Belongs to the UPF0346 family
MEAEOFIB_00829 1.03e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEAEOFIB_00830 8e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEAEOFIB_00831 2.97e-211 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MEAEOFIB_00832 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEAEOFIB_00833 2.24e-198 - - - D - - - DNA integration
MEAEOFIB_00834 6.28e-218 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MEAEOFIB_00835 4.32e-133 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEAEOFIB_00836 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEAEOFIB_00837 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEAEOFIB_00838 1.03e-122 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MEAEOFIB_00839 3.78e-219 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MEAEOFIB_00840 7.86e-92 - - - S - - - Belongs to the HesB IscA family
MEAEOFIB_00841 4.48e-98 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MEAEOFIB_00842 1.93e-117 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MEAEOFIB_00843 5.48e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MEAEOFIB_00844 2.93e-313 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MEAEOFIB_00845 8.83e-306 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
MEAEOFIB_00846 0.0 - - - EP - - - Psort location Cytoplasmic, score
MEAEOFIB_00848 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MEAEOFIB_00849 1.74e-61 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MEAEOFIB_00850 9.26e-57 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MEAEOFIB_00851 2.9e-310 yhjX - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MEAEOFIB_00852 6.75e-22 ycnB - - U - - - Belongs to the major facilitator superfamily
MEAEOFIB_00853 8.31e-31 eriC - - P ko:K03281 - ko00000 chloride
MEAEOFIB_00854 7.58e-31 eriC - - P ko:K03281 - ko00000 chloride
MEAEOFIB_00855 2.83e-35 eriC - - P ko:K03281 - ko00000 chloride
MEAEOFIB_00856 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MEAEOFIB_00857 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MEAEOFIB_00858 8.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MEAEOFIB_00859 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MEAEOFIB_00860 4.19e-285 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEAEOFIB_00861 2.31e-232 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
MEAEOFIB_00862 1.96e-184 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MEAEOFIB_00863 2.44e-125 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MEAEOFIB_00864 1.21e-48 - - - - - - - -
MEAEOFIB_00865 5.88e-174 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_00866 4.27e-155 - - - U ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEAEOFIB_00867 1.8e-179 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MEAEOFIB_00868 1.51e-69 - - - - - - - -
MEAEOFIB_00869 2.34e-214 - 1.1.1.399, 1.1.1.95 - CH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_00870 1.43e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEAEOFIB_00871 2.52e-187 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MEAEOFIB_00872 2.01e-119 ymdB - - S - - - Macro domain protein
MEAEOFIB_00873 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MEAEOFIB_00874 1.73e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MEAEOFIB_00875 1.41e-59 - - - - - - - -
MEAEOFIB_00876 4.63e-266 - - - S - - - Putative metallopeptidase domain
MEAEOFIB_00877 9.08e-260 - - - S - - - associated with various cellular activities
MEAEOFIB_00878 1.16e-149 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MEAEOFIB_00879 1.36e-85 yeaO - - S - - - Protein of unknown function, DUF488
MEAEOFIB_00881 1.83e-158 yrkL - - S - - - Flavodoxin-like fold
MEAEOFIB_00882 8.76e-73 - - - - - - - -
MEAEOFIB_00883 1.24e-139 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MEAEOFIB_00884 6.55e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEAEOFIB_00885 6.86e-138 - - - - - - - -
MEAEOFIB_00886 1.11e-35 - - - - - - - -
MEAEOFIB_00887 1.16e-206 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MEAEOFIB_00888 1.84e-78 - - - - - - - -
MEAEOFIB_00889 8.13e-243 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEAEOFIB_00890 7.99e-86 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEAEOFIB_00891 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MEAEOFIB_00892 2.85e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEAEOFIB_00894 1.11e-105 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEAEOFIB_00895 2.69e-62 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEAEOFIB_00896 1.04e-214 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
MEAEOFIB_00897 7.13e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MEAEOFIB_00898 3.72e-139 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MEAEOFIB_00899 6.33e-293 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MEAEOFIB_00900 2.09e-131 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MEAEOFIB_00901 1.21e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEAEOFIB_00902 8.93e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MEAEOFIB_00903 6.34e-182 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEAEOFIB_00904 4.55e-74 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MEAEOFIB_00905 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
MEAEOFIB_00906 2.12e-253 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MEAEOFIB_00907 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEAEOFIB_00909 1.7e-141 pgm1 - - G - - - phosphoglycerate mutase
MEAEOFIB_00910 2.84e-103 - - - C - - - aldo keto reductase
MEAEOFIB_00911 6.96e-22 - - - C - - - aldo keto reductase
MEAEOFIB_00912 6.6e-255 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEAEOFIB_00913 6.36e-277 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_00914 1.14e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MEAEOFIB_00915 1.08e-287 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MEAEOFIB_00916 3.57e-136 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MEAEOFIB_00917 1.14e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MEAEOFIB_00918 5.84e-77 - - - C - - - FMN binding
MEAEOFIB_00919 6.62e-08 - - - S - - - Domain of unknown function (DUF4190)
MEAEOFIB_00920 5.11e-104 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MEAEOFIB_00921 3.48e-182 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MEAEOFIB_00922 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MEAEOFIB_00923 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MEAEOFIB_00924 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MEAEOFIB_00925 9.83e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MEAEOFIB_00926 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MEAEOFIB_00927 8.24e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEAEOFIB_00928 6.43e-106 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEAEOFIB_00929 3.15e-312 steT - - E ko:K03294 - ko00000 amino acid
MEAEOFIB_00930 1.96e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEAEOFIB_00931 3.34e-68 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEAEOFIB_00932 3.4e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MEAEOFIB_00933 2.48e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEAEOFIB_00934 2.04e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MEAEOFIB_00935 2.65e-133 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MEAEOFIB_00936 6.81e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEAEOFIB_00937 1.25e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEAEOFIB_00938 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MEAEOFIB_00939 6.51e-128 ywlG - - S - - - Belongs to the UPF0340 family
MEAEOFIB_00940 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEAEOFIB_00941 6.44e-263 yacL - - S - - - domain protein
MEAEOFIB_00942 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEAEOFIB_00943 3.41e-125 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MEAEOFIB_00944 4.42e-71 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MEAEOFIB_00945 7.13e-158 - 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEAEOFIB_00946 6.97e-142 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MEAEOFIB_00947 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MEAEOFIB_00948 1.32e-271 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MEAEOFIB_00949 5.22e-229 - - - S - - - Protein of unknown function (DUF2785)
MEAEOFIB_00951 8.44e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MEAEOFIB_00952 7.67e-43 - - - S - - - Protein of unknown function (DUF2969)
MEAEOFIB_00953 9.42e-234 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MEAEOFIB_00954 6.88e-278 - - - M - - - EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
MEAEOFIB_00955 6.65e-39 - - - S - - - Protein of unknown function (DUF1146)
MEAEOFIB_00956 1.19e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MEAEOFIB_00957 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEAEOFIB_00958 1.03e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEAEOFIB_00959 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEAEOFIB_00960 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEAEOFIB_00961 5.31e-78 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEAEOFIB_00962 2.13e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEAEOFIB_00963 5.66e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MEAEOFIB_00964 3.15e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MEAEOFIB_00965 1.11e-164 yibF - - S - - - overlaps another CDS with the same product name
MEAEOFIB_00966 9.1e-249 yibE - - S - - - overlaps another CDS with the same product name
MEAEOFIB_00967 7.8e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEAEOFIB_00968 1.28e-293 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEAEOFIB_00969 8.89e-246 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEAEOFIB_00970 7.82e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEAEOFIB_00971 4.39e-207 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEAEOFIB_00972 5.11e-139 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MEAEOFIB_00973 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MEAEOFIB_00974 6.15e-180 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
MEAEOFIB_00975 2.31e-63 - - - - - - - -
MEAEOFIB_00976 4.89e-11 odh 1.5.1.28 - C ko:K04940 - ko00000,ko01000 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
MEAEOFIB_00977 3.81e-168 - - - C - - - NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
MEAEOFIB_00978 9.29e-150 - - - M - - - racemase activity, acting on amino acids and derivatives
MEAEOFIB_00979 0.0 - - - E ko:K03758 - ko00000,ko02000 Amino acid permease
MEAEOFIB_00980 5.43e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MEAEOFIB_00981 6.18e-83 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEAEOFIB_00982 2.91e-21 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEAEOFIB_00983 3.27e-40 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEAEOFIB_00984 2.68e-55 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEAEOFIB_00985 2.73e-118 - - - S - - - Fic/DOC family
MEAEOFIB_00986 5.73e-67 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
MEAEOFIB_00987 2.6e-314 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
MEAEOFIB_00988 4.56e-58 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
MEAEOFIB_00989 6.84e-152 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
MEAEOFIB_00990 1.96e-267 - - - E - - - Aminotransferase
MEAEOFIB_00993 1.27e-120 - - - S - - - Phage minor capsid protein 2
MEAEOFIB_00994 7.4e-209 - - - I - - - alpha/beta hydrolase fold
MEAEOFIB_00995 5.27e-81 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MEAEOFIB_00996 1.41e-06 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
MEAEOFIB_00998 7.18e-207 - - - S - - - DUF218 domain
MEAEOFIB_00999 7.7e-212 yvgN - - C - - - Aldo keto reductase
MEAEOFIB_01000 1.85e-105 - - - S - - - ECF-type riboflavin transporter, S component
MEAEOFIB_01001 1.75e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MEAEOFIB_01002 6.95e-301 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
MEAEOFIB_01003 3.99e-121 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MEAEOFIB_01004 6.9e-258 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
MEAEOFIB_01005 3.98e-229 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEAEOFIB_01006 1.64e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MEAEOFIB_01007 2.58e-12 fabG1 1.1.1.100, 1.1.1.140, 1.1.1.30, 1.1.1.304, 1.1.1.6, 1.1.1.69, 1.1.1.76 - IQ ko:K00019,ko:K00046,ko:K00059,ko:K00068,ko:K03366,ko:K07535,ko:K22251 ko00051,ko00061,ko00072,ko00333,ko00362,ko00561,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00051,map00061,map00072,map00333,map00362,map00561,map00650,map00780,map01040,map01100,map01120,map01130,map01212,map01220 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MEAEOFIB_01008 3.01e-56 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MEAEOFIB_01009 4.91e-264 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEAEOFIB_01010 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEAEOFIB_01011 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MEAEOFIB_01012 4.19e-239 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MEAEOFIB_01013 5.3e-200 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MEAEOFIB_01014 8.91e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEAEOFIB_01015 8.92e-87 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MEAEOFIB_01016 1.18e-103 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEAEOFIB_01017 7.11e-228 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MEAEOFIB_01018 3.73e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MEAEOFIB_01019 3.81e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MEAEOFIB_01020 3.04e-163 - - - F - - - glutamine amidotransferase
MEAEOFIB_01021 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEAEOFIB_01022 2.81e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MEAEOFIB_01023 1.72e-36 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MEAEOFIB_01024 5.58e-198 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MEAEOFIB_01025 3.35e-221 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
MEAEOFIB_01026 4.22e-212 - - - G - - - Phosphotransferase enzyme family
MEAEOFIB_01027 3.94e-221 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MEAEOFIB_01028 1.71e-192 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MEAEOFIB_01029 5.48e-123 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MEAEOFIB_01030 1.58e-202 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MEAEOFIB_01031 3.01e-41 - - - S - - - CRISPR-associated protein (Cas_Csn2)
MEAEOFIB_01033 5.41e-94 - - - I - - - Hydrolase, alpha beta domain protein
MEAEOFIB_01035 9.98e-124 - - - S - - - integral membrane protein
MEAEOFIB_01036 3.92e-220 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MEAEOFIB_01038 9.74e-72 - - - - - - - -
MEAEOFIB_01039 1.83e-231 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MEAEOFIB_01040 1.5e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEAEOFIB_01041 4.23e-76 - - - - - - - -
MEAEOFIB_01042 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEAEOFIB_01043 2.56e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEAEOFIB_01044 1.01e-108 - - - K - - - Transcriptional regulator
MEAEOFIB_01045 1.4e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MEAEOFIB_01046 1.47e-267 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MEAEOFIB_01047 2.74e-79 yxeM - - ET ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MEAEOFIB_01048 5.11e-60 yxeL - - K - - - acetyltransferase
MEAEOFIB_01049 1.97e-97 yxeN - - U ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
MEAEOFIB_01050 3.05e-100 yxeO - - E ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MEAEOFIB_01051 5.99e-185 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
MEAEOFIB_01052 2.96e-214 - 4.3.2.2, 5.5.1.2 - F ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminus
MEAEOFIB_01053 3.05e-108 - - - S - - - MmgE/PrpD family
MEAEOFIB_01055 2.29e-145 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
MEAEOFIB_01056 1.08e-145 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
MEAEOFIB_01057 1.62e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01058 3.54e-195 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MEAEOFIB_01059 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MEAEOFIB_01060 3.63e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEAEOFIB_01061 4.8e-251 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MEAEOFIB_01062 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEAEOFIB_01063 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEAEOFIB_01064 1.98e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEAEOFIB_01065 1.36e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEAEOFIB_01066 1.51e-174 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MEAEOFIB_01067 1.61e-42 - - - S - - - Protein of unknown function (DUF2992)
MEAEOFIB_01068 2.8e-70 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MEAEOFIB_01069 1.6e-116 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MEAEOFIB_01070 1.07e-34 - - - L - - - Psort location Cytoplasmic, score
MEAEOFIB_01071 4.49e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
MEAEOFIB_01072 3.92e-48 - - - S - - - SnoaL-like domain
MEAEOFIB_01073 3.22e-26 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
MEAEOFIB_01074 4.03e-316 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MEAEOFIB_01075 1.73e-215 hrpQ 4.6.1.1 - T ko:K01768,ko:K03220,ko:K10914 ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111 ko00000,ko00001,ko00002,ko01000,ko02044,ko03000 histone H2A K63-linked ubiquitination
MEAEOFIB_01076 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEAEOFIB_01077 8.32e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEAEOFIB_01078 1.17e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEAEOFIB_01079 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MEAEOFIB_01080 9.91e-224 ydbI - - K - - - AI-2E family transporter
MEAEOFIB_01081 9.93e-17 - - - K - - - transcriptional regulator
MEAEOFIB_01082 8.24e-291 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MEAEOFIB_01083 6.15e-66 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MEAEOFIB_01084 6.92e-213 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MEAEOFIB_01085 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEAEOFIB_01087 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MEAEOFIB_01089 1.24e-219 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEAEOFIB_01090 6.3e-99 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEAEOFIB_01091 9.16e-208 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MEAEOFIB_01092 5.52e-209 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
MEAEOFIB_01093 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEAEOFIB_01094 1.34e-200 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEAEOFIB_01096 6.52e-290 - - - - - - - -
MEAEOFIB_01097 2.27e-247 flp - - V - - - Beta-lactamase
MEAEOFIB_01098 8.23e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
MEAEOFIB_01099 5.71e-157 - - - S ko:K07090 - ko00000 membrane transporter protein
MEAEOFIB_01100 2.87e-233 XK27_12525 - - S - - - AI-2E family transporter
MEAEOFIB_01101 1.09e-272 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MEAEOFIB_01102 9.13e-203 rssA - - S - - - Phospholipase, patatin family
MEAEOFIB_01103 1.15e-209 - - - K - - - LysR substrate binding domain
MEAEOFIB_01104 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MEAEOFIB_01105 1.89e-172 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
MEAEOFIB_01106 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEAEOFIB_01107 3.16e-313 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
MEAEOFIB_01108 6.96e-175 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MEAEOFIB_01110 8.81e-98 uspA3 - - T - - - universal stress protein
MEAEOFIB_01111 1.79e-77 - - - - - - - -
MEAEOFIB_01112 6.63e-10 - - - - - - - -
MEAEOFIB_01113 3.56e-199 - - - - - - - -
MEAEOFIB_01114 1.28e-97 - - - K - - - Transcriptional regulator
MEAEOFIB_01115 1.34e-233 ybcH - - D ko:K06889 - ko00000 Alpha beta
MEAEOFIB_01116 9.46e-96 - - - O - - - OsmC-like protein
MEAEOFIB_01117 1.31e-244 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
MEAEOFIB_01118 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
MEAEOFIB_01119 2.52e-22 - - - - - - - -
MEAEOFIB_01120 3.54e-148 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MEAEOFIB_01121 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01122 1.66e-130 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MEAEOFIB_01123 3.41e-231 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MEAEOFIB_01124 2.51e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MEAEOFIB_01125 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MEAEOFIB_01126 1.3e-44 copZ - - P - - - Heavy-metal-associated domain
MEAEOFIB_01127 8.02e-130 dpsB - - P - - - Belongs to the Dps family
MEAEOFIB_01128 2.68e-142 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
MEAEOFIB_01129 1.27e-220 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEAEOFIB_01130 0.0 - - - L - - - Helicase C-terminal domain protein
MEAEOFIB_01131 5.37e-72 - - - S - - - MazG-like family
MEAEOFIB_01132 1.79e-137 - - - I - - - PAP2 superfamily
MEAEOFIB_01133 8.63e-253 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MEAEOFIB_01134 3.52e-124 - - - - - - - -
MEAEOFIB_01135 2.79e-284 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MEAEOFIB_01136 2.18e-216 - - - V - - - Beta-lactamase enzyme family
MEAEOFIB_01137 6.16e-163 potE - - E - - - Amino Acid
MEAEOFIB_01138 6.48e-172 potE - - E - - - Amino Acid
MEAEOFIB_01140 1.25e-140 - - - - - - - -
MEAEOFIB_01141 3.18e-211 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
MEAEOFIB_01142 2.44e-211 - - - K - - - LysR substrate binding domain
MEAEOFIB_01143 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MEAEOFIB_01144 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MEAEOFIB_01145 1.86e-246 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
MEAEOFIB_01146 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MEAEOFIB_01147 1.87e-139 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEAEOFIB_01148 3.82e-43 nlhH_1 - - I ko:K01066 - ko00000,ko01000 acetylesterase activity
MEAEOFIB_01150 1.1e-197 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MEAEOFIB_01151 2.59e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEAEOFIB_01152 0.0 - - - L - - - DNA helicase
MEAEOFIB_01153 1.32e-220 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEAEOFIB_01154 1.12e-285 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MEAEOFIB_01155 7.53e-239 - - - - - - - -
MEAEOFIB_01156 2.31e-165 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MEAEOFIB_01157 6.35e-125 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MEAEOFIB_01158 2.63e-112 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MEAEOFIB_01159 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
MEAEOFIB_01160 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEAEOFIB_01161 1.83e-186 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MEAEOFIB_01162 3.77e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEAEOFIB_01163 1.7e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEAEOFIB_01164 4.04e-205 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEAEOFIB_01165 4.04e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MEAEOFIB_01166 4.67e-122 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEAEOFIB_01167 2.81e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
MEAEOFIB_01168 5.86e-191 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MEAEOFIB_01169 2.33e-300 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEAEOFIB_01170 5.19e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEAEOFIB_01171 1.89e-78 - - - - - - - -
MEAEOFIB_01172 1.65e-110 - - - L - - - Helix-turn-helix domain
MEAEOFIB_01173 8.65e-226 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
MEAEOFIB_01174 8.04e-163 cpkA 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Amino acid kinase family
MEAEOFIB_01175 5.87e-21 - - - S - - - Protein of unknown function (DUF2877)
MEAEOFIB_01176 1.48e-272 - - - C - - - Protein of unknown function (DUF1116)
MEAEOFIB_01177 2.44e-304 fdrA - - C ko:K02381 - ko00000 CoA-ligase
MEAEOFIB_01178 1.15e-258 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
MEAEOFIB_01179 1.69e-163 ylbA 3.5.3.26 - S ko:K14977 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 protein, possibly involved in glyoxylate utilization
MEAEOFIB_01180 2.24e-291 allC 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 Peptidase family M20/M25/M40
MEAEOFIB_01181 1.73e-285 - 3.5.2.3, 3.5.2.5 - F ko:K01465,ko:K01466 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEAEOFIB_01182 4.28e-154 - - - FH ko:K03457 - ko00000 Permease for cytosine/purines, uracil, thiamine, allantoin
MEAEOFIB_01183 1.69e-84 - - - I - - - alpha/beta hydrolase fold
MEAEOFIB_01184 1.39e-234 - - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
MEAEOFIB_01185 4.13e-194 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
MEAEOFIB_01186 2.7e-230 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_01187 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MEAEOFIB_01189 5.36e-299 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MEAEOFIB_01190 1.15e-200 - - - S - - - Alpha beta hydrolase
MEAEOFIB_01191 1.07e-202 - - - GM - - - NAD(P)H-binding
MEAEOFIB_01192 3.71e-195 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEAEOFIB_01194 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MEAEOFIB_01195 1.05e-274 - - - G - - - Major Facilitator Superfamily
MEAEOFIB_01196 7.56e-15 aroH 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
MEAEOFIB_01197 1.32e-272 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEAEOFIB_01198 4.48e-131 - - - - - - - -
MEAEOFIB_01199 2.62e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEAEOFIB_01200 2.27e-248 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MEAEOFIB_01201 4.33e-116 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MEAEOFIB_01202 1.5e-277 aspB3 - - E - - - DegT/DnrJ/EryC1/StrS aminotransferase family
MEAEOFIB_01203 1.28e-230 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_01204 2.7e-79 XK27_08315 - - M - - - Sulfatase
MEAEOFIB_01205 2.27e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MEAEOFIB_01206 1.66e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MEAEOFIB_01207 3.25e-97 gtcA - - S - - - Teichoic acid glycosylation protein
MEAEOFIB_01209 2.35e-304 yfmL - - L - - - DEAD DEAH box helicase
MEAEOFIB_01210 1.16e-242 mocA - - S - - - Oxidoreductase
MEAEOFIB_01211 5.17e-83 - - - S - - - Domain of unknown function (DUF4828)
MEAEOFIB_01212 2.46e-132 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MEAEOFIB_01213 5.04e-203 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MEAEOFIB_01214 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MEAEOFIB_01215 4.1e-177 - - - S - - - NADPH-dependent FMN reductase
MEAEOFIB_01216 1.01e-44 yneR - - S - - - Belongs to the HesB IscA family
MEAEOFIB_01217 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MEAEOFIB_01218 4.16e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MEAEOFIB_01219 4.44e-136 - - - - - - - -
MEAEOFIB_01220 1.13e-275 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MEAEOFIB_01221 2.39e-131 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEAEOFIB_01222 3.5e-36 rhaS4 - - K - - - Transcriptional regulator
MEAEOFIB_01223 6.84e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MEAEOFIB_01224 7.37e-207 - - - EG - - - EamA-like transporter family
MEAEOFIB_01225 1.85e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEAEOFIB_01226 7.8e-181 - - - G - - - MucBP domain
MEAEOFIB_01227 2.31e-125 - - - S - - - Pfam:DUF3816
MEAEOFIB_01228 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEAEOFIB_01229 1.18e-140 pncA - - Q - - - Isochorismatase family
MEAEOFIB_01230 3.26e-162 - - - F - - - NUDIX domain
MEAEOFIB_01231 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MEAEOFIB_01232 5.36e-07 - - - - - - - -
MEAEOFIB_01233 5.05e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MEAEOFIB_01234 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEAEOFIB_01235 3.25e-293 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MEAEOFIB_01236 1.28e-253 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MEAEOFIB_01237 9.75e-232 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEAEOFIB_01238 6.63e-52 - - - S - - - Protein of unknown function (DUF1797)
MEAEOFIB_01239 1.88e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
MEAEOFIB_01240 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
MEAEOFIB_01241 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MEAEOFIB_01243 2.38e-109 - - - K - - - GNAT family
MEAEOFIB_01244 5.19e-158 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MEAEOFIB_01245 1.52e-204 yvgN - - S - - - Aldo keto reductase
MEAEOFIB_01246 1.5e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEAEOFIB_01247 3.69e-168 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
MEAEOFIB_01249 2.67e-75 - - - - - - - -
MEAEOFIB_01251 3.22e-11 - - - - - - - -
MEAEOFIB_01252 1.02e-102 - - - K - - - Winged helix-turn-helix DNA-binding
MEAEOFIB_01253 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01254 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MEAEOFIB_01255 3.76e-245 ampC - - V - - - Beta-lactamase
MEAEOFIB_01256 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEAEOFIB_01257 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MEAEOFIB_01258 3.41e-188 - - - S - - - haloacid dehalogenase-like hydrolase
MEAEOFIB_01259 8.99e-168 gntR - - K - - - UbiC transcription regulator-associated domain protein
MEAEOFIB_01260 4.94e-114 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEAEOFIB_01261 2.98e-164 - - - - - - - -
MEAEOFIB_01262 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEAEOFIB_01263 4.35e-198 - - - G - - - Xylose isomerase domain protein TIM barrel
MEAEOFIB_01264 6.93e-112 - - - K - - - Domain of unknown function (DUF1836)
MEAEOFIB_01265 1.8e-111 - - - GM - - - epimerase
MEAEOFIB_01266 0.0 yhdP - - S - - - Transporter associated domain
MEAEOFIB_01267 3.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MEAEOFIB_01268 1.23e-96 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
MEAEOFIB_01269 2.96e-265 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
MEAEOFIB_01270 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEAEOFIB_01272 2.01e-125 - - - K - - - Bacterial regulatory proteins, tetR family
MEAEOFIB_01273 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01274 3.08e-68 - - - S - - - FMN_bind
MEAEOFIB_01275 4.81e-36 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEAEOFIB_01276 2.21e-147 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
MEAEOFIB_01277 1.36e-27 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
MEAEOFIB_01278 1e-30 XK27_06785 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MEAEOFIB_01279 5.27e-105 - - - K - - - Transcriptional regulator
MEAEOFIB_01280 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEAEOFIB_01281 4.13e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEAEOFIB_01282 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MEAEOFIB_01283 5.52e-68 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MEAEOFIB_01284 6.93e-198 yneP - - L ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MEAEOFIB_01285 2.34e-95 - - - S - - - NADPH-dependent FMN reductase
MEAEOFIB_01286 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
MEAEOFIB_01287 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEAEOFIB_01288 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
MEAEOFIB_01289 2.7e-21 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
MEAEOFIB_01291 3.84e-233 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MEAEOFIB_01292 5.77e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MEAEOFIB_01293 7.17e-123 - - - - - - - -
MEAEOFIB_01295 7.66e-222 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEAEOFIB_01296 4.28e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
MEAEOFIB_01297 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MEAEOFIB_01299 2.06e-108 - - - P - - - Cation efflux family
MEAEOFIB_01300 3.69e-26 yycN - - K - - - Acetyltransferase (GNAT) domain
MEAEOFIB_01301 9.5e-222 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEAEOFIB_01302 7.3e-155 - - - S - - - VIT family
MEAEOFIB_01303 3.76e-150 - - - S - - - membrane
MEAEOFIB_01304 2e-143 - - - S - - - VIT family
MEAEOFIB_01305 2.49e-110 - - - T - - - Belongs to the universal stress protein A family
MEAEOFIB_01306 1.59e-29 elaA - - S ko:K02348 - ko00000 acyltransferase COG2153
MEAEOFIB_01307 2.58e-273 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEAEOFIB_01308 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEAEOFIB_01309 3.3e-77 - - - - - - - -
MEAEOFIB_01310 3.27e-95 - - - K - - - MerR HTH family regulatory protein
MEAEOFIB_01311 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MEAEOFIB_01312 1.84e-147 - - - S - - - Domain of unknown function (DUF4811)
MEAEOFIB_01313 1.85e-139 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MEAEOFIB_01314 5.79e-215 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEAEOFIB_01316 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEAEOFIB_01317 3.78e-282 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEAEOFIB_01318 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MEAEOFIB_01319 1.63e-210 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MEAEOFIB_01320 1.76e-316 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MEAEOFIB_01321 1.05e-223 citR - - K - - - sugar-binding domain protein
MEAEOFIB_01322 1.41e-265 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
MEAEOFIB_01323 3.24e-250 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MEAEOFIB_01324 3.36e-61 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MEAEOFIB_01325 3.07e-209 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MEAEOFIB_01326 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MEAEOFIB_01327 0.0 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MEAEOFIB_01328 4.49e-187 - - - I - - - Alpha/beta hydrolase family
MEAEOFIB_01329 2.13e-27 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 transmembrane transport
MEAEOFIB_01330 8.98e-149 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MEAEOFIB_01331 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MEAEOFIB_01332 6.57e-223 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MEAEOFIB_01333 8.7e-94 ywnA - - K - - - Transcriptional regulator
MEAEOFIB_01334 4.11e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEAEOFIB_01335 3.18e-268 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MEAEOFIB_01336 2.61e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MEAEOFIB_01337 1.61e-182 yycI - - S - - - YycH protein
MEAEOFIB_01338 2.34e-302 yycH - - S - - - YycH protein
MEAEOFIB_01339 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEAEOFIB_01340 8.69e-167 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MEAEOFIB_01342 8.76e-299 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MEAEOFIB_01343 9.65e-220 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MEAEOFIB_01344 1.42e-215 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MEAEOFIB_01345 8.27e-182 yceF - - P ko:K05794 - ko00000 membrane
MEAEOFIB_01346 6.96e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEAEOFIB_01347 6.99e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEAEOFIB_01348 9.89e-207 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MEAEOFIB_01349 1.7e-235 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MEAEOFIB_01350 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MEAEOFIB_01351 7.61e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MEAEOFIB_01352 3.55e-296 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MEAEOFIB_01353 1.47e-284 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MEAEOFIB_01354 5.05e-51 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MEAEOFIB_01355 3.35e-135 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MEAEOFIB_01356 2.03e-33 yitW - - S - - - DNA methyltransferase
MEAEOFIB_01357 1.11e-39 - - - M - - - domain protein
MEAEOFIB_01358 2.35e-50 - - - M - - - LPXTG-motif cell wall anchor domain protein
MEAEOFIB_01359 3.98e-26 - - - M - - - LPXTG-motif cell wall anchor domain protein
MEAEOFIB_01360 6.39e-05 - - - M - - - LPXTG-motif cell wall anchor domain protein
MEAEOFIB_01361 1.95e-110 lutC - - S ko:K00782 - ko00000 LUD domain
MEAEOFIB_01362 2.26e-309 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
MEAEOFIB_01363 4.61e-165 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
MEAEOFIB_01364 6.35e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MEAEOFIB_01365 5.09e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEAEOFIB_01366 3.28e-48 ynzC - - S - - - UPF0291 protein
MEAEOFIB_01367 1.05e-36 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MEAEOFIB_01368 2.51e-218 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MEAEOFIB_01369 2.67e-39 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
MEAEOFIB_01370 1.99e-42 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
MEAEOFIB_01371 9.7e-116 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
MEAEOFIB_01373 1.29e-271 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
MEAEOFIB_01374 6.71e-198 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MEAEOFIB_01375 4.24e-183 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MEAEOFIB_01377 1.39e-279 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MEAEOFIB_01379 2.1e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MEAEOFIB_01380 1.45e-127 - - - K - - - Virulence activator alpha C-term
MEAEOFIB_01381 3.37e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MEAEOFIB_01382 9.01e-132 cadD - - P - - - Cadmium resistance transporter
MEAEOFIB_01383 3.64e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MEAEOFIB_01384 2.93e-135 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEAEOFIB_01385 9.86e-201 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MEAEOFIB_01386 2.62e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEAEOFIB_01388 4.44e-21 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MEAEOFIB_01389 2.93e-69 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MEAEOFIB_01390 1.32e-83 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MEAEOFIB_01391 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
MEAEOFIB_01392 2.04e-269 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MEAEOFIB_01393 1.54e-272 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
MEAEOFIB_01394 0.0 yhdP - - S - - - Transporter associated domain
MEAEOFIB_01395 3.32e-267 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MEAEOFIB_01396 2.71e-202 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
MEAEOFIB_01397 1.26e-213 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MEAEOFIB_01398 3.52e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEAEOFIB_01399 6.19e-300 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEAEOFIB_01400 7.74e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEAEOFIB_01401 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEAEOFIB_01402 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MEAEOFIB_01403 4.66e-236 - - - D - - - nuclear chromosome segregation
MEAEOFIB_01404 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MEAEOFIB_01405 2.64e-209 - - - S - - - Calcineurin-like phosphoesterase
MEAEOFIB_01408 1.1e-147 - - - - - - - -
MEAEOFIB_01409 4.3e-168 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MEAEOFIB_01410 8.7e-166 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MEAEOFIB_01411 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEAEOFIB_01412 1.91e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEAEOFIB_01413 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MEAEOFIB_01414 3.19e-105 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MEAEOFIB_01415 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MEAEOFIB_01416 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEAEOFIB_01417 1.85e-76 - - - L ko:K07497 - ko00000 hmm pf00665
MEAEOFIB_01418 2.61e-53 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MEAEOFIB_01419 6.59e-139 - - - GK - - - ROK family
MEAEOFIB_01420 2.42e-77 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MEAEOFIB_01421 3.42e-08 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEAEOFIB_01422 9.66e-122 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MEAEOFIB_01423 2.82e-185 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MEAEOFIB_01424 1.23e-202 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MEAEOFIB_01425 9.64e-201 spxB 1.2.3.3, 1.2.5.1, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577 ko00620,ko00630,ko01100,map00620,map00630,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MEAEOFIB_01426 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MEAEOFIB_01427 2.73e-227 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MEAEOFIB_01428 5.93e-149 - - - S - - - HAD hydrolase, family IA, variant
MEAEOFIB_01429 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MEAEOFIB_01430 8.41e-235 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
MEAEOFIB_01431 8.88e-216 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
MEAEOFIB_01432 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEAEOFIB_01433 1.64e-108 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MEAEOFIB_01434 3.38e-140 yciB - - M - - - ErfK YbiS YcfS YnhG
MEAEOFIB_01435 2.2e-116 XK27_08315 - - M - - - Sulfatase
MEAEOFIB_01436 5.86e-192 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MEAEOFIB_01437 4.37e-43 - - - S - - - Protein of unknown function (DUF2922)
MEAEOFIB_01439 5.86e-188 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MEAEOFIB_01440 1.73e-152 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MEAEOFIB_01441 1.35e-188 cps1D - - M - - - Domain of unknown function (DUF4422)
MEAEOFIB_01442 1.04e-118 cps3F - - - - - - -
MEAEOFIB_01443 1.51e-38 - - - M - - - biosynthesis protein
MEAEOFIB_01444 2.69e-278 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MEAEOFIB_01445 1.24e-256 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MEAEOFIB_01446 1.35e-87 - - - S - - - enterobacterial common antigen metabolic process
MEAEOFIB_01447 3.52e-91 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
MEAEOFIB_01448 7.51e-125 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MEAEOFIB_01449 7.52e-61 - - - T ko:K14988 ko02020,map02020 ko00000,ko00001,ko00002,ko01001,ko02022 Histidine kinase
MEAEOFIB_01450 3.66e-60 - - - T - - - regulator
MEAEOFIB_01452 1.21e-125 - - - F - - - AAA domain
MEAEOFIB_01453 7.69e-108 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01454 2.19e-261 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease)
MEAEOFIB_01455 6.22e-52 - - - L ko:K07483 - ko00000 Transposase
MEAEOFIB_01456 1.85e-119 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
MEAEOFIB_01457 2.18e-246 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEAEOFIB_01458 8.73e-41 - - - K - - - LytTr DNA-binding domain
MEAEOFIB_01459 1.54e-45 - - - S - - - Protein of unknown function (DUF3021)
MEAEOFIB_01460 1.55e-56 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MEAEOFIB_01461 7.76e-72 azlD - - E - - - Branched-chain amino acid transport
MEAEOFIB_01462 1.19e-134 azlC - - E - - - azaleucine resistance protein AzlC
MEAEOFIB_01463 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MEAEOFIB_01464 4.34e-299 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MEAEOFIB_01465 6.66e-201 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEAEOFIB_01466 8.44e-128 - - - K - - - Acetyltransferase (GNAT) domain
MEAEOFIB_01467 1.02e-145 ylbE - - GM - - - NAD(P)H-binding
MEAEOFIB_01468 1.45e-152 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEAEOFIB_01469 6.09e-173 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MEAEOFIB_01470 1.39e-129 - - - - - - - -
MEAEOFIB_01471 4.02e-205 - - - S - - - EDD domain protein, DegV family
MEAEOFIB_01472 0.0 FbpA - - K - - - Fibronectin-binding protein
MEAEOFIB_01473 4.17e-35 - - - L - - - nuclease
MEAEOFIB_01474 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEAEOFIB_01475 4.99e-60 - - - - - - - -
MEAEOFIB_01476 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MEAEOFIB_01477 3.73e-239 - - - E - - - Zinc-binding dehydrogenase
MEAEOFIB_01478 1.74e-118 - - - K - - - Bacterial regulatory proteins, tetR family
MEAEOFIB_01479 6.51e-34 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MEAEOFIB_01480 1.03e-151 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MEAEOFIB_01481 8.31e-158 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01482 3.72e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MEAEOFIB_01485 4.19e-13 - - - - - - - -
MEAEOFIB_01486 5.38e-47 - - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
MEAEOFIB_01487 1.82e-09 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
MEAEOFIB_01488 3.95e-67 - - - - - - - -
MEAEOFIB_01489 1.13e-150 yckA - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEAEOFIB_01490 3.42e-199 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MEAEOFIB_01491 1.85e-137 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
MEAEOFIB_01492 7.04e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MEAEOFIB_01493 8.6e-93 esbA - - S - - - Family of unknown function (DUF5322)
MEAEOFIB_01494 1.8e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEAEOFIB_01495 8.61e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEAEOFIB_01496 2.43e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MEAEOFIB_01497 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MEAEOFIB_01498 4.19e-153 - 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MEAEOFIB_01499 3.89e-136 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MEAEOFIB_01502 1.95e-176 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
MEAEOFIB_01503 5.51e-197 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
MEAEOFIB_01504 3.14e-227 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MEAEOFIB_01505 1.75e-211 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MEAEOFIB_01506 8.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MEAEOFIB_01511 2.06e-201 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MEAEOFIB_01512 2.74e-286 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEAEOFIB_01513 5.51e-147 - - - S - - - Calcineurin-like phosphoesterase
MEAEOFIB_01514 2.22e-125 yutD - - S - - - Protein of unknown function (DUF1027)
MEAEOFIB_01515 4.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEAEOFIB_01516 9.59e-22 - - - S - - - Protein of unknown function (DUF1461)
MEAEOFIB_01517 3.38e-141 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MEAEOFIB_01518 1.41e-214 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEAEOFIB_01519 3.4e-99 - - - S - - - Bacterial membrane protein, YfhO
MEAEOFIB_01520 2.99e-126 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MEAEOFIB_01521 1.3e-119 - - - M - - - transferase activity, transferring glycosyl groups
MEAEOFIB_01522 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEAEOFIB_01523 2.76e-206 ykoT - - M - - - Glycosyl transferase family 2
MEAEOFIB_01524 5.62e-214 yueF - - S - - - AI-2E family transporter
MEAEOFIB_01525 4.64e-204 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MEAEOFIB_01526 8.03e-10 - - - - - - - -
MEAEOFIB_01527 9.96e-81 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
MEAEOFIB_01528 0.0 - 1.7.2.5 - P ko:K04561 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Cytochrome C and Quinol oxidase polypeptide I
MEAEOFIB_01529 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
MEAEOFIB_01530 7.47e-90 - - - - - - - -
MEAEOFIB_01531 1.17e-135 - - - S - - - Domain of unknown function (DUF4767)
MEAEOFIB_01532 6.7e-72 - - - K - - - Helix-turn-helix domain
MEAEOFIB_01533 2.1e-219 - 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MEAEOFIB_01534 1.03e-98 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
MEAEOFIB_01535 4.36e-67 ybjQ - - S - - - Belongs to the UPF0145 family
MEAEOFIB_01536 1.75e-74 - 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEAEOFIB_01537 3.26e-190 - 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEAEOFIB_01538 2.56e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEAEOFIB_01539 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEAEOFIB_01540 6.56e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MEAEOFIB_01541 7.14e-111 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEAEOFIB_01543 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEAEOFIB_01544 3.14e-57 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEAEOFIB_01545 1.86e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEAEOFIB_01546 1.02e-28 - - - S - - - Protein of unknown function (DUF2508)
MEAEOFIB_01547 2.41e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEAEOFIB_01548 2.25e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
MEAEOFIB_01549 5.8e-248 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MEAEOFIB_01550 4.98e-74 yabA - - L - - - Involved in initiation control of chromosome replication
MEAEOFIB_01551 1.34e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEAEOFIB_01552 2.16e-187 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MEAEOFIB_01553 8.97e-227 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEAEOFIB_01554 5e-198 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MEAEOFIB_01555 2.87e-28 - - - S - - - Virus attachment protein p12 family
MEAEOFIB_01556 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MEAEOFIB_01557 2e-45 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
MEAEOFIB_01558 2.3e-186 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MEAEOFIB_01559 3e-309 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MEAEOFIB_01560 4.31e-297 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEAEOFIB_01561 2.14e-110 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MEAEOFIB_01562 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MEAEOFIB_01563 7.04e-245 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MEAEOFIB_01564 1.86e-122 - - - S ko:K07002 - ko00000 Serine hydrolase
MEAEOFIB_01565 2.22e-78 - - - S - - - branched-chain amino acid
MEAEOFIB_01566 2.57e-175 - - - E - - - AzlC protein
MEAEOFIB_01567 1.79e-264 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MEAEOFIB_01568 1.53e-267 hpk31 - - T - - - Histidine kinase
MEAEOFIB_01569 1.44e-156 vanR - - K - - - response regulator
MEAEOFIB_01570 3.21e-120 - - - S ko:K09705 - ko00000 Cupin superfamily (DUF985)
MEAEOFIB_01573 2.06e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEAEOFIB_01574 1.97e-258 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEAEOFIB_01575 3.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MEAEOFIB_01576 3.06e-203 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MEAEOFIB_01577 4.54e-96 - - - L - - - Helix-turn-helix domain
MEAEOFIB_01579 8.34e-179 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MEAEOFIB_01581 1.46e-208 - - - K - - - Transcriptional regulator
MEAEOFIB_01582 8.2e-152 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MEAEOFIB_01583 3.99e-51 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MEAEOFIB_01584 6.65e-90 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MEAEOFIB_01586 4.84e-29 - - - S - - - Bacterial transferase hexapeptide (six repeats)
MEAEOFIB_01587 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MEAEOFIB_01588 3.72e-195 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEAEOFIB_01589 1.06e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
MEAEOFIB_01590 5.67e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MEAEOFIB_01591 3.88e-160 - - - C - - - nitroreductase
MEAEOFIB_01592 1.11e-203 - - - EG - - - EamA-like transporter family
MEAEOFIB_01593 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEAEOFIB_01594 5.07e-85 - - - IQ - - - dehydrogenase reductase
MEAEOFIB_01595 1.62e-134 - - - K - - - acetyltransferase
MEAEOFIB_01596 9.32e-223 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MEAEOFIB_01597 2.94e-164 sptS - - T - - - Histidine kinase
MEAEOFIB_01598 1.35e-100 dltr - - K - - - response regulator
MEAEOFIB_01599 1.16e-146 - - - T - - - Region found in RelA / SpoT proteins
MEAEOFIB_01600 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MEAEOFIB_01601 1.63e-76 - - - - - - - -
MEAEOFIB_01602 0.0 - - - M - - - Iron Transport-associated domain
MEAEOFIB_01603 9.26e-130 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
MEAEOFIB_01604 3.64e-192 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MEAEOFIB_01605 2.46e-198 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEAEOFIB_01606 1.55e-181 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01607 1.25e-298 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
MEAEOFIB_01608 5.73e-203 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MEAEOFIB_01609 9.66e-07 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MEAEOFIB_01610 1.18e-73 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEAEOFIB_01611 2.6e-63 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MEAEOFIB_01612 8.31e-74 citR - - K - - - sugar-binding domain protein
MEAEOFIB_01613 3.62e-42 citR - - K - - - sugar-binding domain protein
MEAEOFIB_01614 4.24e-59 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MEAEOFIB_01615 1.74e-106 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MEAEOFIB_01616 3.45e-301 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MEAEOFIB_01617 2.93e-132 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MEAEOFIB_01618 2.42e-22 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MEAEOFIB_01619 1.86e-86 - - - I - - - Alpha/beta hydrolase family
MEAEOFIB_01620 2.53e-147 - - - L - - - Integrase
MEAEOFIB_01621 1.86e-58 - - - K - - - transcriptional regulator
MEAEOFIB_01622 3.29e-27 - - - GM - - - NmrA-like family
MEAEOFIB_01623 1.06e-103 - - - GM - - - NmrA-like family
MEAEOFIB_01624 1.06e-32 - - - C - - - Flavodoxin
MEAEOFIB_01625 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
MEAEOFIB_01626 1.11e-256 arcD - - S - - - C4-dicarboxylate anaerobic carrier
MEAEOFIB_01627 6.25e-242 arcT - - E - - - Dipeptidase
MEAEOFIB_01628 3.68e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MEAEOFIB_01629 9.95e-108 - - - F - - - Hydrolase, NUDIX family
MEAEOFIB_01630 2.82e-267 - - - S ko:K06915 - ko00000 AAA-like domain
MEAEOFIB_01631 0.0 fusA1 - - J - - - elongation factor G
MEAEOFIB_01632 0.0 XK27_03440 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
MEAEOFIB_01633 1.77e-76 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
MEAEOFIB_01634 8.84e-105 - - - S - - - Domain of unknown function (DUF4391)
MEAEOFIB_01635 0.0 - - - L - - - helicase superfamily c-terminal domain
MEAEOFIB_01636 2.31e-35 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MEAEOFIB_01637 6e-05 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MEAEOFIB_01638 2.61e-188 XK27_00020 - - J - - - Telomere recombination
MEAEOFIB_01639 3.49e-139 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEAEOFIB_01640 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEAEOFIB_01641 1.01e-249 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MEAEOFIB_01642 2.19e-305 - - - EGP ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MEAEOFIB_01643 1.15e-166 yocS - - S ko:K03453 - ko00000 Transporter
MEAEOFIB_01644 2.99e-37 XK27_02560 - - S - - - Pfam:DUF59
MEAEOFIB_01645 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
MEAEOFIB_01646 8e-76 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
MEAEOFIB_01647 2.24e-61 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MEAEOFIB_01648 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MEAEOFIB_01649 1.69e-124 - - - V - - - VanZ like family
MEAEOFIB_01650 1.71e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MEAEOFIB_01651 2.74e-81 - - - - - - - -
MEAEOFIB_01652 1.19e-234 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
MEAEOFIB_01653 2.34e-301 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MEAEOFIB_01654 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MEAEOFIB_01655 5.31e-72 - - - L ko:K07491 - ko00000 Transposase IS200 like
MEAEOFIB_01656 1.45e-245 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MEAEOFIB_01658 2.29e-96 - 3.5.3.18 - E ko:K01482 - ko00000,ko01000,ko04147 Amidinotransferase
MEAEOFIB_01659 9.15e-115 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
MEAEOFIB_01660 0.0 sufI - - Q - - - Multicopper oxidase
MEAEOFIB_01661 2.49e-65 - - - K - - - 2 iron, 2 sulfur cluster binding
MEAEOFIB_01662 1.12e-110 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MEAEOFIB_01663 5.13e-147 - - - Q - - - Methyltransferase domain
MEAEOFIB_01665 6.44e-132 - - - S - - - CAAX protease self-immunity
MEAEOFIB_01666 8.81e-129 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEAEOFIB_01667 9.22e-119 - - - EGP - - - Major Facilitator Superfamily
MEAEOFIB_01668 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
MEAEOFIB_01669 8.31e-100 - - - L - - - 4.5 Transposon and IS
MEAEOFIB_01670 1.92e-51 - - - L ko:K07483 - ko00000 Transposase
MEAEOFIB_01671 8.74e-161 - - - S - - - Membrane
MEAEOFIB_01672 3.18e-299 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEAEOFIB_01673 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MEAEOFIB_01674 1.13e-227 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEAEOFIB_01675 7.72e-180 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEAEOFIB_01676 1.03e-213 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
MEAEOFIB_01679 4.1e-18 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 ATPase, P-type transporting, HAD superfamily, subfamily IC
MEAEOFIB_01680 1.91e-65 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 ATPase, P-type transporting, HAD superfamily, subfamily IC
MEAEOFIB_01682 1.03e-106 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MEAEOFIB_01683 3.92e-55 - - - - - - - -
MEAEOFIB_01684 2.02e-216 - - - GK - - - ROK family
MEAEOFIB_01685 1.68e-163 - - - C - - - Oxidoreductase NAD-binding domain
MEAEOFIB_01686 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
MEAEOFIB_01687 3.13e-133 - - - K - - - Acetyltransferase (GNAT) family
MEAEOFIB_01688 2.51e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEAEOFIB_01689 7.05e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEAEOFIB_01690 6.33e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEAEOFIB_01691 3.39e-94 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MEAEOFIB_01694 1.4e-200 repA - - S - - - Replication initiator protein A
MEAEOFIB_01695 7.21e-47 - - - - - - - -
MEAEOFIB_01696 9.03e-190 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MEAEOFIB_01697 7.7e-234 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEAEOFIB_01698 1.18e-106 - - - S - - - Domain of unknown function (DUF4352)
MEAEOFIB_01699 5.51e-142 yicL - - EG - - - EamA-like transporter family
MEAEOFIB_01700 1.08e-83 - - - - - - - -
MEAEOFIB_01701 2.16e-42 - - - - - - - -
MEAEOFIB_01702 3.96e-89 - - - S - - - pyridoxamine 5-phosphate
MEAEOFIB_01703 1.8e-228 - - - K - - - WYL domain
MEAEOFIB_01704 4.66e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MEAEOFIB_01705 1.65e-53 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MEAEOFIB_01706 4.07e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MEAEOFIB_01707 4.58e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MEAEOFIB_01708 2.43e-261 yhdG - - E ko:K03294 - ko00000 Amino Acid
MEAEOFIB_01709 3.13e-95 - - - F - - - Nudix hydrolase
MEAEOFIB_01710 7.64e-133 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MEAEOFIB_01711 7.28e-110 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MEAEOFIB_01712 4.69e-10 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MEAEOFIB_01713 1.12e-213 - - - - - - - -
MEAEOFIB_01714 1.54e-248 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MEAEOFIB_01715 6e-122 - - - K - - - Transcriptional regulator (TetR family)
MEAEOFIB_01716 9.6e-314 yhgE - - V ko:K01421 - ko00000 domain protein
MEAEOFIB_01717 2.2e-272 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
MEAEOFIB_01718 4.65e-185 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MEAEOFIB_01719 2.04e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MEAEOFIB_01720 2.22e-207 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MEAEOFIB_01721 1.02e-186 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MEAEOFIB_01722 1.47e-41 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MEAEOFIB_01723 2.13e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEAEOFIB_01724 1.37e-174 - - - S - - - Protein of unknown function (DUF1129)
MEAEOFIB_01725 1.41e-263 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEAEOFIB_01726 1.51e-131 - - - K - - - DNA-templated transcription, initiation
MEAEOFIB_01729 6.59e-27 - - - S - - - Protein of unknown function (DUF4256)
MEAEOFIB_01730 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MEAEOFIB_01731 3.02e-136 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MEAEOFIB_01732 4.27e-17 - - - L ko:K07483 - ko00000 Helix-turn-helix domain
MEAEOFIB_01733 2.4e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01734 4.4e-170 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MEAEOFIB_01735 9.99e-147 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MEAEOFIB_01736 1.5e-58 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphotyrosine protein phosphatase
MEAEOFIB_01737 4.83e-224 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
MEAEOFIB_01738 5.24e-168 - - - E - - - Peptidase family M20/M25/M40
MEAEOFIB_01739 2.85e-165 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
MEAEOFIB_01740 4.98e-206 allB 3.5.2.3, 3.5.2.5 - F ko:K01465,ko:K01466 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEAEOFIB_01741 8.73e-196 - - - FH ko:K03457 - ko00000 Permease for cytosine/purines, uracil, thiamine, allantoin
MEAEOFIB_01742 9.36e-108 - 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Amidase
MEAEOFIB_01743 1.84e-80 tnp1216 - - L ko:K07498 - ko00000 DDE domain
MEAEOFIB_01744 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
MEAEOFIB_01745 8.8e-202 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
MEAEOFIB_01746 7.82e-110 is18 - - L - - - COG2801 Transposase and inactivated derivatives
MEAEOFIB_01747 7.44e-82 is18 - - L - - - Integrase core domain
MEAEOFIB_01748 4.13e-51 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
MEAEOFIB_01749 2.69e-47 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
MEAEOFIB_01750 2.83e-127 tnpR - - L - - - Resolvase, N terminal domain
MEAEOFIB_01751 1.3e-34 - - - L - - - MULE transposase domain
MEAEOFIB_01752 5.12e-132 - - - L ko:K07497 - ko00000 hmm pf00665
MEAEOFIB_01753 1.05e-160 - - - L - - - Helix-turn-helix domain
MEAEOFIB_01754 3.91e-307 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MEAEOFIB_01755 4.68e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEAEOFIB_01756 1.41e-285 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MEAEOFIB_01757 4.99e-227 - - - - - - - -
MEAEOFIB_01758 2.52e-66 - - - S - - - Cupredoxin-like domain
MEAEOFIB_01759 1.33e-67 - - - S - - - Cupredoxin-like domain
MEAEOFIB_01760 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MEAEOFIB_01761 5.41e-33 - - - EGP - - - Major Facilitator
MEAEOFIB_01762 4.72e-128 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MEAEOFIB_01763 4.07e-48 - - - K - - - Putative DNA-binding domain
MEAEOFIB_01764 1.66e-78 - - - - - - - -
MEAEOFIB_01765 5.79e-132 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
MEAEOFIB_01766 6.01e-41 - - - - - - - -
MEAEOFIB_01767 1.25e-09 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MEAEOFIB_01769 1.71e-228 repA - - S - - - Replication initiator protein A
MEAEOFIB_01770 8.05e-09 rlrB - - K - - - LysR substrate binding domain protein
MEAEOFIB_01771 1.2e-67 lysR - - K - - - Transcriptional regulator
MEAEOFIB_01772 2.2e-33 rlrB - - K - - - LysR substrate binding domain protein
MEAEOFIB_01773 1.37e-271 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MEAEOFIB_01774 5.81e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MEAEOFIB_01775 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MEAEOFIB_01776 1.36e-272 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEAEOFIB_01777 2.59e-229 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MEAEOFIB_01778 1.99e-231 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MEAEOFIB_01779 3.02e-255 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_01780 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MEAEOFIB_01781 1.85e-240 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MEAEOFIB_01782 4.86e-210 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MEAEOFIB_01783 4.33e-162 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEAEOFIB_01784 7.3e-212 - - - I - - - alpha/beta hydrolase fold
MEAEOFIB_01785 5.89e-172 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MEAEOFIB_01786 3.6e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MEAEOFIB_01787 1.19e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEAEOFIB_01788 5.28e-153 pgm3 - - G - - - phosphoglycerate mutase
MEAEOFIB_01789 6.89e-151 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MEAEOFIB_01790 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MEAEOFIB_01791 5.58e-248 bdhA 1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4 - C ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MEAEOFIB_01792 1e-107 - - - C - - - Zinc-binding dehydrogenase
MEAEOFIB_01793 8.12e-75 - - - C - - - Zinc-binding dehydrogenase
MEAEOFIB_01794 4.6e-131 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
MEAEOFIB_01795 3.14e-179 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01796 1.48e-137 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEAEOFIB_01797 1.92e-207 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
MEAEOFIB_01798 6.99e-99 ywnA - - K - - - Transcriptional regulator
MEAEOFIB_01799 5.23e-97 - - - O ko:K07397 - ko00000 OsmC-like protein
MEAEOFIB_01800 2.27e-96 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MEAEOFIB_01801 5.58e-90 - - - L ko:K06400 - ko00000 Recombinase
MEAEOFIB_01802 3.81e-205 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MEAEOFIB_01803 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MEAEOFIB_01804 7.33e-78 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEAEOFIB_01805 1.1e-260 yngD - - S ko:K07097 - ko00000 DHHA1 domain
MEAEOFIB_01806 0.0 - - - S - - - ABC transporter, ATP-binding protein
MEAEOFIB_01807 1.33e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MEAEOFIB_01808 3.6e-191 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MEAEOFIB_01809 1.54e-169 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01811 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEAEOFIB_01812 4.46e-182 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEAEOFIB_01813 1.1e-184 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MEAEOFIB_01814 7.38e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MEAEOFIB_01815 1.37e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MEAEOFIB_01816 4.38e-92 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MEAEOFIB_01818 5.56e-41 potE - - E - - - Amino Acid
MEAEOFIB_01819 3.69e-278 potE - - E - - - Amino Acid
MEAEOFIB_01820 7.51e-238 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEAEOFIB_01821 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
MEAEOFIB_01822 4.33e-84 - - - S ko:K07126 - ko00000 Sel1-like repeats.
MEAEOFIB_01823 9.76e-82 - - - S - - - YjbR
MEAEOFIB_01825 5.92e-157 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MEAEOFIB_01826 7.52e-96 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEAEOFIB_01827 5.74e-20 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEAEOFIB_01828 1.6e-19 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
MEAEOFIB_01829 1.57e-32 - - - D ko:K19158 - ko00000,ko01000,ko02048 mRNA cleavage
MEAEOFIB_01830 4.29e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MEAEOFIB_01831 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MEAEOFIB_01832 7.09e-115 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEAEOFIB_01833 5.56e-41 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEAEOFIB_01834 2.14e-16 - - - I - - - alpha/beta hydrolase fold
MEAEOFIB_01835 2.4e-100 mleR - - K - - - LysR family
MEAEOFIB_01836 2.41e-286 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MEAEOFIB_01838 2.23e-230 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MEAEOFIB_01839 2.48e-117 - - - S - - - NADPH-dependent FMN reductase
MEAEOFIB_01840 4.48e-11 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MEAEOFIB_01841 7.48e-155 pnb - - C - - - nitroreductase
MEAEOFIB_01842 6.67e-106 - 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha/beta hydrolase family
MEAEOFIB_01844 1.05e-22 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MEAEOFIB_01846 2.54e-51 - - - C - - - Aldo keto reductase
MEAEOFIB_01847 5.11e-06 - - - S - - - CsbD-like
MEAEOFIB_01849 7.43e-08 - - - C - - - Aldo/keto reductase family
MEAEOFIB_01850 4.08e-116 - - - P - - - Cadmium resistance transporter
MEAEOFIB_01852 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MEAEOFIB_01853 7.87e-33 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEAEOFIB_01855 3.19e-150 - - - C ko:K08317 - ko00000,ko01000 dehydrogenase
MEAEOFIB_01856 8.76e-82 yuxO - - Q - - - Thioesterase superfamily
MEAEOFIB_01857 2e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MEAEOFIB_01858 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MEAEOFIB_01859 1.02e-276 - - - G - - - Transporter, major facilitator family protein
MEAEOFIB_01860 1.77e-263 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
MEAEOFIB_01861 5.29e-110 - - - - - - - -
MEAEOFIB_01862 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEAEOFIB_01863 1.35e-161 pgm3 - - G - - - phosphoglycerate mutase family
MEAEOFIB_01864 1.13e-191 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MEAEOFIB_01865 1.25e-206 mleR2 - - K - - - LysR family transcriptional regulator
MEAEOFIB_01866 0.0 - - - S - - - Putative threonine/serine exporter
MEAEOFIB_01867 1.29e-152 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
MEAEOFIB_01868 1.85e-239 - - - I - - - Alpha beta
MEAEOFIB_01869 7.04e-139 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MEAEOFIB_01870 2.29e-28 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_01871 1.33e-173 - 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 UDP-N-acetylglucosamine 2-epimerase
MEAEOFIB_01872 9.04e-129 - - - G - - - Glycosyl hydrolases family 8
MEAEOFIB_01873 9.91e-230 ydaM - - M - - - Glycosyl transferase family group 2
MEAEOFIB_01875 1.52e-12 - - - - - - - -
MEAEOFIB_01876 7.26e-63 - - - - - - - -
MEAEOFIB_01877 4.46e-71 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAEOFIB_01878 7.59e-90 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MEAEOFIB_01879 2.6e-69 - - - L ko:K07491 - ko00000 Transposase IS200 like
MEAEOFIB_01880 0.0 - - - E - - - amino acid
MEAEOFIB_01881 8.85e-259 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEAEOFIB_01883 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MEAEOFIB_01884 4.81e-282 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEAEOFIB_01885 3.55e-61 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MEAEOFIB_01887 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MEAEOFIB_01888 1.46e-72 XK27_09800 - - I - - - Acyltransferase family
MEAEOFIB_01889 1.83e-100 XK27_09800 - - I - - - Acyltransferase family
MEAEOFIB_01890 1.07e-89 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
MEAEOFIB_01891 4.18e-198 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
MEAEOFIB_01892 1.33e-274 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MEAEOFIB_01893 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEAEOFIB_01894 1.37e-72 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
MEAEOFIB_01895 1.22e-222 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEAEOFIB_01896 0.0 - - - G - - - Major Facilitator Superfamily
MEAEOFIB_01897 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MEAEOFIB_01898 1.89e-168 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MEAEOFIB_01899 0.0 yclK - - T - - - Histidine kinase
MEAEOFIB_01900 1.68e-194 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MEAEOFIB_01901 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MEAEOFIB_01902 6.81e-180 ywfI - - S ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 Chlorite dismutase
MEAEOFIB_01903 4.34e-314 - - - EGP - - - Transporter, major facilitator family protein
MEAEOFIB_01904 1.25e-220 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MEAEOFIB_01905 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
MEAEOFIB_01907 0.000393 - - - S - - - Polysaccharide biosynthesis protein
MEAEOFIB_01908 1.42e-142 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MEAEOFIB_01909 6.06e-234 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
MEAEOFIB_01910 4.03e-300 yagE - - E - - - Amino acid permease
MEAEOFIB_01911 4.18e-281 - - - S - - - Domain of unknown function (DUF389)
MEAEOFIB_01912 6.07e-42 - - - - - - - -
MEAEOFIB_01913 1.76e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEAEOFIB_01914 1.83e-92 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEAEOFIB_01916 5.06e-64 - - - M - - - group 2 family protein
MEAEOFIB_01917 5.52e-91 - - - M - - - Glycosyl transferases group 1
MEAEOFIB_01918 2.08e-84 - - - K - - - Transcriptional regulator, GntR family
MEAEOFIB_01919 5.71e-202 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEAEOFIB_01921 7.61e-268 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MEAEOFIB_01922 6.99e-189 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MEAEOFIB_01923 7.68e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MEAEOFIB_01924 8.3e-217 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
MEAEOFIB_01925 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEAEOFIB_01926 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MEAEOFIB_01927 1.02e-34 - - - - - - - -
MEAEOFIB_01928 2.16e-99 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
MEAEOFIB_01929 2.23e-281 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MEAEOFIB_01930 1.25e-102 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
MEAEOFIB_01931 6.11e-106 usp5 - - T - - - universal stress protein
MEAEOFIB_01932 3.8e-101 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEAEOFIB_01934 9.7e-117 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MEAEOFIB_01935 8.06e-88 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MEAEOFIB_01936 3.01e-245 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the alpha-IPM synthase homocitrate synthase family
MEAEOFIB_01939 1.21e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEAEOFIB_01943 3.17e-93 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
MEAEOFIB_01944 9.84e-105 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MEAEOFIB_01945 6.87e-117 yejD 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 nucleoside 2-deoxyribosyltransferase
MEAEOFIB_01946 1.36e-65 - - - K - - - TRANSCRIPTIONal
MEAEOFIB_01947 3.14e-114 - - - L ko:K07497 - ko00000 hmm pf00665
MEAEOFIB_01948 8.34e-101 - - - - - - - -
MEAEOFIB_01949 6.48e-87 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MEAEOFIB_01950 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MEAEOFIB_01951 2.6e-167 tnp1216 - - L ko:K07498 - ko00000 DDE domain
MEAEOFIB_01953 1.62e-68 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MEAEOFIB_01954 6.8e-100 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MEAEOFIB_01956 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
MEAEOFIB_01957 5.16e-70 - - - L ko:K07484 - ko00000 Transposase IS66 family
MEAEOFIB_01959 7.07e-31 yitW - - S - - - Iron-sulfur cluster assembly protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)