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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MEGPCKMM_00001	8.79e-10	-	-	-	-	-	-	-	-
MEGPCKMM_00002	1.24e-55	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MEGPCKMM_00003	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MEGPCKMM_00004	7.7e-129	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MEGPCKMM_00005	3.65e-238	tnpA	-	-	L	-	-	-	Transposase
MEGPCKMM_00006	2.86e-45	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEGPCKMM_00008	2.8e-63	tetA	-	-	EGP	ko:K08151,ko:K08153	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
MEGPCKMM_00009	2.17e-204	-	-	-	G	-	-	-	Fructosamine kinase
MEGPCKMM_00010	1.67e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEGPCKMM_00011	4.49e-199	-	-	-	S	-	-	-	PAC2 family
MEGPCKMM_00017	2.65e-32	-	-	-	-	-	-	-	-
MEGPCKMM_00018	5.2e-123	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MEGPCKMM_00020	3.74e-127	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
MEGPCKMM_00021	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEGPCKMM_00022	8.83e-151	pgsA1	2.7.8.11, 2.7.8.5	-	I	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
MEGPCKMM_00023	4.4e-247	htrB	2.3.1.265	-	M	ko:K22311	-	ko00000,ko01000	Bacterial lipid A biosynthesis acyltransferase
MEGPCKMM_00024	1.34e-240	pimA	2.4.1.345	GT4	M	ko:K08256	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MEGPCKMM_00025	6.09e-175	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MEGPCKMM_00026	6.75e-132	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MEGPCKMM_00027	5.91e-141	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEGPCKMM_00028	1.2e-260	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEGPCKMM_00029	1.9e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
MEGPCKMM_00030	2.2e-133	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEGPCKMM_00031	5.72e-283	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MEGPCKMM_00032	1.85e-212	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MEGPCKMM_00033	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_00034	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MEGPCKMM_00035	5.52e-37	-	-	-	-	-	-	-	-
MEGPCKMM_00036	3.45e-221	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MEGPCKMM_00037	7.04e-186	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MEGPCKMM_00038	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MEGPCKMM_00040	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MEGPCKMM_00041	0.0	-	-	-	K	-	-	-	WYL domain
MEGPCKMM_00042	2.35e-67	-	-	-	-	-	-	-	-
MEGPCKMM_00043	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
MEGPCKMM_00044	5.49e-82	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MEGPCKMM_00045	2.61e-179	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
MEGPCKMM_00046	5e-88	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEGPCKMM_00047	3.58e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEGPCKMM_00048	5.12e-91	-	-	-	-	-	-	-	-
MEGPCKMM_00049	2.48e-170	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MEGPCKMM_00050	2.66e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MEGPCKMM_00051	1.81e-197	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MEGPCKMM_00052	1.09e-63	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
MEGPCKMM_00053	2.38e-225	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MEGPCKMM_00054	4.93e-141	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEGPCKMM_00055	5.79e-201	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
MEGPCKMM_00056	3.18e-55	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
MEGPCKMM_00057	2.68e-157	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
MEGPCKMM_00058	4.78e-235	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEGPCKMM_00059	3.55e-206	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MEGPCKMM_00060	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MEGPCKMM_00061	0.00074	-	-	-	-	-	-	-	-
MEGPCKMM_00062	3.13e-11	-	-	-	-	-	-	-	-
MEGPCKMM_00063	4.39e-148	-	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
MEGPCKMM_00064	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MEGPCKMM_00065	6.65e-100	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MEGPCKMM_00066	2.11e-178	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEGPCKMM_00067	4.44e-173	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MEGPCKMM_00068	3.54e-149	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00069	7.65e-136	-	-	-	K	-	-	-	WHG domain
MEGPCKMM_00070	3.81e-294	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MEGPCKMM_00071	5.59e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
MEGPCKMM_00072	1.16e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEGPCKMM_00073	5.41e-172	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MEGPCKMM_00074	2.5e-177	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEGPCKMM_00075	1.03e-208	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MEGPCKMM_00076	5.55e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEGPCKMM_00077	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
MEGPCKMM_00079	2.97e-266	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
MEGPCKMM_00080	1.2e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
MEGPCKMM_00081	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
MEGPCKMM_00082	1.13e-137	-	-	-	M	-	-	-	Peptidase family M23
MEGPCKMM_00083	1.16e-81	-	-	-	-	-	-	-	-
MEGPCKMM_00085	1.79e-117	-	-	-	-	-	-	-	-
MEGPCKMM_00087	7.97e-251	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEGPCKMM_00088	3.49e-118	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
MEGPCKMM_00089	7.23e-202	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
MEGPCKMM_00090	1.84e-146	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
MEGPCKMM_00091	2.44e-239	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MEGPCKMM_00092	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
MEGPCKMM_00093	2.36e-171	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
MEGPCKMM_00094	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MEGPCKMM_00095	5.23e-213	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MEGPCKMM_00096	5.76e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MEGPCKMM_00097	1.72e-206	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MEGPCKMM_00098	9.97e-94	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
MEGPCKMM_00101	3.21e-134	-	-	-	-	-	-	-	-
MEGPCKMM_00102	6.21e-159	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MEGPCKMM_00103	4.35e-94	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEGPCKMM_00104	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEGPCKMM_00106	2.27e-246	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEGPCKMM_00107	1.06e-171	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEGPCKMM_00108	3.59e-148	-	-	-	-	-	-	-	-
MEGPCKMM_00109	4.6e-307	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEGPCKMM_00110	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
MEGPCKMM_00111	3.85e-166	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MEGPCKMM_00112	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MEGPCKMM_00113	8.73e-236	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEGPCKMM_00114	9.59e-152	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
MEGPCKMM_00115	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
MEGPCKMM_00116	8.69e-185	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MEGPCKMM_00117	4.09e-248	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
MEGPCKMM_00118	2.75e-261	-	-	-	L	-	-	-	Tetratricopeptide repeat
MEGPCKMM_00119	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEGPCKMM_00120	3.62e-116	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MEGPCKMM_00121	2.15e-198	butA	1.1.1.100, 1.1.1.304, 1.1.1.76	-	IQ	ko:K00059,ko:K03366	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MEGPCKMM_00122	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MEGPCKMM_00123	8.47e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEGPCKMM_00124	1.23e-119	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MEGPCKMM_00125	5.7e-235	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEGPCKMM_00126	1.31e-305	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MEGPCKMM_00127	5.02e-228	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MEGPCKMM_00128	7.16e-278	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MEGPCKMM_00129	1.64e-260	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEGPCKMM_00130	5.69e-190	-	-	-	-	-	-	-	-
MEGPCKMM_00131	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
MEGPCKMM_00132	3.65e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEGPCKMM_00133	9.87e-217	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEGPCKMM_00134	1.8e-18	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MEGPCKMM_00135	2.42e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MEGPCKMM_00136	3.03e-169	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEGPCKMM_00137	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00138	2.66e-139	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MEGPCKMM_00139	1.05e-287	ytrE	-	-	V	ko:K02003,ko:K10038	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	lipoprotein transporter activity
MEGPCKMM_00140	6.74e-209	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
MEGPCKMM_00141	1.03e-55	-	-	-	-	-	-	-	-
MEGPCKMM_00142	7.53e-272	-	-	-	T	-	-	-	Histidine kinase
MEGPCKMM_00143	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
MEGPCKMM_00144	6.92e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
MEGPCKMM_00145	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MEGPCKMM_00146	1.07e-188	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
MEGPCKMM_00147	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MEGPCKMM_00148	3.49e-143	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MEGPCKMM_00149	5.3e-263	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MEGPCKMM_00150	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEGPCKMM_00151	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MEGPCKMM_00152	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEGPCKMM_00153	7.71e-193	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00154	1.3e-283	-	-	-	E	-	-	-	Aminotransferase class I and II
MEGPCKMM_00155	1.93e-172	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MEGPCKMM_00156	2.94e-85	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEGPCKMM_00157	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEGPCKMM_00158	7.3e-210	-	-	-	S	-	-	-	Aldo/keto reductase family
MEGPCKMM_00159	1.9e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
MEGPCKMM_00160	7.88e-182	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MEGPCKMM_00161	1.17e-93	yccF	-	-	S	-	-	-	Inner membrane component domain
MEGPCKMM_00162	1.42e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MEGPCKMM_00163	2.23e-184	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00164	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_00166	8.63e-255	-	-	-	L	-	-	-	Transposase, Mutator family
MEGPCKMM_00167	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MEGPCKMM_00168	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MEGPCKMM_00169	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
MEGPCKMM_00170	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
MEGPCKMM_00171	1.25e-239	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
MEGPCKMM_00172	1.1e-256	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00173	2.23e-142	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00174	1.51e-198	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MEGPCKMM_00175	1.1e-182	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
MEGPCKMM_00176	1.4e-189	-	-	-	S	ko:K06889	-	ko00000	Serine aminopeptidase, S33
MEGPCKMM_00177	5.33e-294	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
MEGPCKMM_00178	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
MEGPCKMM_00179	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MEGPCKMM_00180	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
MEGPCKMM_00181	1.7e-234	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
MEGPCKMM_00182	6.14e-178	-	-	-	-	-	-	-	-
MEGPCKMM_00183	4.88e-266	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
MEGPCKMM_00184	1.15e-103	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MEGPCKMM_00185	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEGPCKMM_00186	4.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
MEGPCKMM_00187	1.78e-202	-	-	-	-	-	-	-	-
MEGPCKMM_00188	2.56e-56	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
MEGPCKMM_00189	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEGPCKMM_00190	4.22e-45	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MEGPCKMM_00191	9.65e-114	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MEGPCKMM_00192	1.57e-180	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEGPCKMM_00193	1.79e-246	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MEGPCKMM_00194	1.98e-231	-	-	-	S	-	-	-	Protein of unknown function DUF58
MEGPCKMM_00195	9.9e-116	-	-	-	-	-	-	-	-
MEGPCKMM_00196	1.13e-249	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MEGPCKMM_00197	1.23e-230	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MEGPCKMM_00198	1.09e-125	-	-	-	-	-	-	-	-
MEGPCKMM_00200	0.0	-	-	-	S	-	-	-	PGAP1-like protein
MEGPCKMM_00201	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
MEGPCKMM_00202	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
MEGPCKMM_00203	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
MEGPCKMM_00204	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MEGPCKMM_00205	8.24e-41	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MEGPCKMM_00206	4.64e-220	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
MEGPCKMM_00207	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
MEGPCKMM_00208	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
MEGPCKMM_00209	5.9e-163	-	-	-	S	-	-	-	SNARE associated Golgi protein
MEGPCKMM_00210	8.15e-110	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
MEGPCKMM_00211	1.06e-235	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEGPCKMM_00212	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEGPCKMM_00213	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
MEGPCKMM_00214	8.72e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEGPCKMM_00215	4.74e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEGPCKMM_00216	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
MEGPCKMM_00217	6.35e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MEGPCKMM_00218	5.67e-232	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MEGPCKMM_00219	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MEGPCKMM_00220	6.95e-306	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MEGPCKMM_00221	1.34e-103	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEGPCKMM_00222	7.02e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEGPCKMM_00223	8.01e-123	-	-	-	-	-	-	-	-
MEGPCKMM_00224	1.07e-157	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEGPCKMM_00225	2.25e-294	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEGPCKMM_00226	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEGPCKMM_00227	1.34e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEGPCKMM_00228	8.2e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEGPCKMM_00230	2.78e-253	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
MEGPCKMM_00231	3.4e-300	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
MEGPCKMM_00232	8.01e-297	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEGPCKMM_00233	4.83e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MEGPCKMM_00234	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
MEGPCKMM_00235	4.93e-286	-	-	-	S	-	-	-	Short C-terminal domain
MEGPCKMM_00236	4.96e-139	-	-	-	-	-	-	-	-
MEGPCKMM_00237	2.77e-90	-	-	-	-	-	-	-	-
MEGPCKMM_00238	2.73e-162	-	-	-	-	-	-	-	-
MEGPCKMM_00239	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_00241	1.97e-140	-	-	-	K	-	-	-	sequence-specific DNA binding
MEGPCKMM_00242	1.97e-116	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MEGPCKMM_00243	1.21e-130	-	-	-	-	-	-	-	-
MEGPCKMM_00244	9.81e-297	-	-	-	S	-	-	-	50S ribosome-binding GTPase
MEGPCKMM_00245	7.52e-95	-	-	-	-	-	-	-	-
MEGPCKMM_00246	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
MEGPCKMM_00247	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEGPCKMM_00248	3.44e-251	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MEGPCKMM_00249	2.74e-305	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MEGPCKMM_00250	0.0	-	-	-	S	-	-	-	Putative esterase
MEGPCKMM_00251	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
MEGPCKMM_00252	2.4e-93	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MEGPCKMM_00253	1.2e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEGPCKMM_00254	6.53e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEGPCKMM_00255	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEGPCKMM_00257	6.68e-282	-	-	-	P	-	-	-	Citrate transporter
MEGPCKMM_00258	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEGPCKMM_00259	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEGPCKMM_00260	1.21e-129	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEGPCKMM_00261	8.52e-122	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEGPCKMM_00262	3.3e-290	gldA	1.1.1.6	-	C	ko:K00005,ko:K08317	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
MEGPCKMM_00263	5.05e-190	-	-	-	S	-	-	-	3-oxo-5-alpha-steroid 4-dehydrogenase
MEGPCKMM_00264	2.04e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MEGPCKMM_00265	9.13e-119	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MEGPCKMM_00266	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
MEGPCKMM_00267	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
MEGPCKMM_00268	8.48e-81	-	-	-	S	-	-	-	Fic/DOC family
MEGPCKMM_00269	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
MEGPCKMM_00270	7.91e-95	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MEGPCKMM_00271	4.86e-84	-	-	-	-	-	-	-	-
MEGPCKMM_00272	3.78e-76	-	-	-	-	-	-	-	-
MEGPCKMM_00274	1.14e-30	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
MEGPCKMM_00275	4.02e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
MEGPCKMM_00278	1.29e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MEGPCKMM_00279	1.01e-221	-	-	-	S	-	-	-	Protein conserved in bacteria
MEGPCKMM_00280	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MEGPCKMM_00281	5.12e-243	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MEGPCKMM_00282	3.07e-284	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MEGPCKMM_00283	9.13e-180	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00284	4.99e-181	oppDF2	-	-	P	ko:K02031,ko:K02032,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00285	8.71e-201	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00286	7.86e-217	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00287	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MEGPCKMM_00288	1.14e-175	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MEGPCKMM_00289	6.41e-89	-	-	-	-	-	-	-	-
MEGPCKMM_00290	2.61e-184	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
MEGPCKMM_00291	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEGPCKMM_00292	1.98e-164	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MEGPCKMM_00293	2.66e-231	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MEGPCKMM_00294	2.6e-197	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00295	6.2e-208	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00296	3.75e-215	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
MEGPCKMM_00297	3.92e-213	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
MEGPCKMM_00298	1.36e-105	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEGPCKMM_00299	3.74e-282	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
MEGPCKMM_00300	2.42e-209	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
MEGPCKMM_00301	1.64e-298	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
MEGPCKMM_00302	1.65e-265	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEGPCKMM_00303	1.57e-236	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MEGPCKMM_00304	6.33e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEGPCKMM_00305	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
MEGPCKMM_00306	1.86e-165	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MEGPCKMM_00307	1.78e-133	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MEGPCKMM_00308	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
MEGPCKMM_00309	6.13e-174	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
MEGPCKMM_00310	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEGPCKMM_00311	7.39e-98	-	-	-	-	-	-	-	-
MEGPCKMM_00312	0.0	-	-	-	L	-	-	-	PIF1-like helicase
MEGPCKMM_00313	1.72e-200	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MEGPCKMM_00314	1.09e-158	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MEGPCKMM_00315	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MEGPCKMM_00316	1.04e-268	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
MEGPCKMM_00317	2.61e-150	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
MEGPCKMM_00318	9.47e-225	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEGPCKMM_00319	9.55e-217	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEGPCKMM_00320	9.15e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MEGPCKMM_00321	8.6e-293	xylR	-	-	GK	-	-	-	ROK family
MEGPCKMM_00322	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MEGPCKMM_00323	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
MEGPCKMM_00324	3.21e-299	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MEGPCKMM_00325	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
MEGPCKMM_00326	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MEGPCKMM_00327	1.07e-203	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00328	1.54e-246	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00329	1.02e-310	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
MEGPCKMM_00330	2.63e-241	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MEGPCKMM_00331	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MEGPCKMM_00332	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MEGPCKMM_00333	1.47e-47	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MEGPCKMM_00334	4.11e-223	-	-	-	-	-	-	-	-
MEGPCKMM_00336	5.11e-184	-	-	-	-	-	-	-	-
MEGPCKMM_00337	6.02e-145	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MEGPCKMM_00338	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
MEGPCKMM_00339	4.14e-91	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEGPCKMM_00340	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
MEGPCKMM_00341	4.03e-221	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
MEGPCKMM_00342	7.39e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
MEGPCKMM_00343	3.66e-186	folK	2.7.6.3, 4.1.2.25	-	H	ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEGPCKMM_00344	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEGPCKMM_00345	2.77e-128	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MEGPCKMM_00346	5e-274	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEGPCKMM_00347	8.49e-301	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
MEGPCKMM_00348	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MEGPCKMM_00349	1.78e-207	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00350	2.55e-307	-	-	-	M	-	-	-	Glycosyl transferase family 21
MEGPCKMM_00351	0.0	-	-	-	S	-	-	-	AI-2E family transporter
MEGPCKMM_00352	5.74e-241	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MEGPCKMM_00356	2.41e-239	-	-	-	K	-	-	-	Periplasmic binding protein domain
MEGPCKMM_00357	4.97e-225	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00358	7.36e-225	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
MEGPCKMM_00359	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00360	2.28e-260	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEGPCKMM_00361	5.97e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
MEGPCKMM_00362	8.48e-132	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
MEGPCKMM_00363	2.76e-80	-	-	-	-	-	-	-	-
MEGPCKMM_00364	7.35e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MEGPCKMM_00365	3.44e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MEGPCKMM_00366	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00367	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MEGPCKMM_00368	2.83e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
MEGPCKMM_00370	7.2e-302	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00371	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00372	1.89e-187	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
MEGPCKMM_00373	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00374	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2130)
MEGPCKMM_00376	0.0	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
MEGPCKMM_00377	1.95e-139	-	-	-	-	-	-	-	-
MEGPCKMM_00378	1.78e-239	-	3.1.3.5	-	S	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase
MEGPCKMM_00379	3.21e-245	-	-	-	S	-	-	-	DUF218 domain
MEGPCKMM_00381	5.36e-206	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEGPCKMM_00382	9.11e-256	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MEGPCKMM_00383	1.04e-129	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
MEGPCKMM_00384	1.46e-170	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
MEGPCKMM_00385	1.12e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEGPCKMM_00386	1.07e-94	-	-	-	O	-	-	-	OsmC-like protein
MEGPCKMM_00387	8.87e-252	-	-	-	T	-	-	-	Universal stress protein family
MEGPCKMM_00388	1.42e-140	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MEGPCKMM_00389	1.91e-228	-	-	-	S	-	-	-	CHAP domain
MEGPCKMM_00390	2.42e-268	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEGPCKMM_00391	4.13e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MEGPCKMM_00392	1.87e-288	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEGPCKMM_00393	2.41e-29	-	-	-	-	-	-	-	-
MEGPCKMM_00394	0.0	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
MEGPCKMM_00395	4.64e-159	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
MEGPCKMM_00396	1.62e-84	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
MEGPCKMM_00397	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
MEGPCKMM_00398	2.91e-179	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEGPCKMM_00399	1.05e-101	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MEGPCKMM_00400	0.0	-	-	-	E	-	-	-	Amino acid permease
MEGPCKMM_00401	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
MEGPCKMM_00402	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
MEGPCKMM_00403	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MEGPCKMM_00404	0.0	-	-	-	E	-	-	-	Phospholipase B
MEGPCKMM_00405	1.71e-186	-	-	-	-	-	-	-	-
MEGPCKMM_00406	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MEGPCKMM_00408	1.71e-38	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
MEGPCKMM_00409	2.29e-166	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MEGPCKMM_00410	2.09e-286	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MEGPCKMM_00411	5.45e-146	-	-	-	-	-	-	-	-
MEGPCKMM_00412	0.0	pspC	-	-	KT	-	-	-	PspC domain
MEGPCKMM_00413	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
MEGPCKMM_00414	8.64e-163	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MEGPCKMM_00415	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
MEGPCKMM_00416	5.96e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
MEGPCKMM_00417	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MEGPCKMM_00418	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MEGPCKMM_00419	1.69e-278	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MEGPCKMM_00420	2.27e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEGPCKMM_00422	7.54e-240	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEGPCKMM_00423	2.05e-164	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEGPCKMM_00424	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
MEGPCKMM_00425	1.12e-128	-	-	-	-	-	-	-	-
MEGPCKMM_00426	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEGPCKMM_00427	9.91e-302	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
MEGPCKMM_00428	5.82e-250	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEGPCKMM_00429	5.79e-122	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEGPCKMM_00430	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEGPCKMM_00431	6.28e-249	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MEGPCKMM_00432	5.94e-208	-	-	-	-	-	-	-	-
MEGPCKMM_00434	6.34e-190	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEGPCKMM_00435	1.16e-92	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MEGPCKMM_00436	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGPCKMM_00437	1.73e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEGPCKMM_00438	1.17e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEGPCKMM_00439	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MEGPCKMM_00440	4.86e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEGPCKMM_00441	4.41e-131	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEGPCKMM_00442	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEGPCKMM_00443	3.98e-100	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MEGPCKMM_00444	1.75e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
MEGPCKMM_00445	6.25e-132	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEGPCKMM_00446	5.96e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEGPCKMM_00447	6.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEGPCKMM_00448	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEGPCKMM_00449	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEGPCKMM_00450	1.94e-136	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEGPCKMM_00451	4.44e-68	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEGPCKMM_00452	5.15e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEGPCKMM_00453	7.84e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEGPCKMM_00454	5.27e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MEGPCKMM_00455	1.15e-99	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEGPCKMM_00456	2.32e-176	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEGPCKMM_00457	2.68e-75	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEGPCKMM_00458	6.95e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEGPCKMM_00459	2.32e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEGPCKMM_00460	1.79e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEGPCKMM_00461	3.41e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MEGPCKMM_00462	1.06e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEGPCKMM_00463	6.58e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MEGPCKMM_00464	3.06e-198	-	-	-	S	-	-	-	YwiC-like protein
MEGPCKMM_00465	3.9e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MEGPCKMM_00466	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MEGPCKMM_00467	1.65e-267	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MEGPCKMM_00468	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MEGPCKMM_00469	6.69e-97	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MEGPCKMM_00470	1.31e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEGPCKMM_00471	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MEGPCKMM_00472	1.73e-157	-	-	-	-	-	-	-	-
MEGPCKMM_00473	3.01e-147	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
MEGPCKMM_00474	1e-243	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEGPCKMM_00476	0.0	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEGPCKMM_00477	7.49e-282	dapC	-	-	E	-	-	-	Aminotransferase class I and II
MEGPCKMM_00478	4.15e-80	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
MEGPCKMM_00479	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
MEGPCKMM_00480	2.74e-302	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MEGPCKMM_00481	2.06e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
MEGPCKMM_00485	4.55e-64	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEGPCKMM_00486	1.73e-257	-	-	-	-	-	-	-	-
MEGPCKMM_00487	1.59e-103	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MEGPCKMM_00488	1.84e-177	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
MEGPCKMM_00489	1.76e-43	-	-	-	S	-	-	-	Putative regulatory protein
MEGPCKMM_00490	8.73e-132	-	-	-	NO	-	-	-	SAF
MEGPCKMM_00491	2.19e-52	-	-	-	-	-	-	-	-
MEGPCKMM_00492	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
MEGPCKMM_00493	0.0	-	-	-	T	-	-	-	Forkhead associated domain
MEGPCKMM_00494	9.38e-68	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEGPCKMM_00495	2.13e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEGPCKMM_00496	2.41e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MEGPCKMM_00497	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
MEGPCKMM_00498	1.51e-188	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEGPCKMM_00499	1.53e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MEGPCKMM_00500	2.63e-218	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MEGPCKMM_00501	3.8e-262	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
MEGPCKMM_00502	1.32e-168	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MEGPCKMM_00503	1.85e-280	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MEGPCKMM_00504	2.15e-155	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEGPCKMM_00505	1.15e-305	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MEGPCKMM_00506	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MEGPCKMM_00507	8.35e-279	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MEGPCKMM_00508	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MEGPCKMM_00509	3.73e-192	-	-	-	D	-	-	-	nuclear chromosome segregation
MEGPCKMM_00510	2.7e-172	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MEGPCKMM_00511	3.41e-193	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MEGPCKMM_00512	1.79e-288	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
MEGPCKMM_00513	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
MEGPCKMM_00514	5.57e-214	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
MEGPCKMM_00515	7.35e-28	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MEGPCKMM_00516	2.38e-100	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MEGPCKMM_00517	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGPCKMM_00518	2.7e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGPCKMM_00519	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MEGPCKMM_00520	2.65e-128	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MEGPCKMM_00521	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MEGPCKMM_00522	2.28e-65	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEGPCKMM_00523	2.28e-238	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MEGPCKMM_00524	4.41e-156	-	-	-	-	-	-	-	-
MEGPCKMM_00526	1.39e-102	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEGPCKMM_00527	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
MEGPCKMM_00528	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
MEGPCKMM_00529	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MEGPCKMM_00530	4.06e-134	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MEGPCKMM_00531	2.36e-216	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
MEGPCKMM_00532	8.38e-188	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MEGPCKMM_00533	2.3e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEGPCKMM_00534	3.53e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEGPCKMM_00535	3.74e-204	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MEGPCKMM_00536	5.51e-46	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEGPCKMM_00538	2.39e-295	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
MEGPCKMM_00539	1.76e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEGPCKMM_00540	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEGPCKMM_00541	1.23e-52	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
MEGPCKMM_00542	7.1e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MEGPCKMM_00543	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
MEGPCKMM_00544	5.31e-295	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
MEGPCKMM_00545	3.25e-155	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
MEGPCKMM_00546	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
MEGPCKMM_00547	1.28e-229	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00548	5.07e-185	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEGPCKMM_00549	3.61e-175	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MEGPCKMM_00550	1.67e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEGPCKMM_00551	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MEGPCKMM_00552	4.94e-287	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mannose-6-phosphate isomerase
MEGPCKMM_00555	3.86e-236	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
MEGPCKMM_00556	2.98e-313	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00557	2.59e-170	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEGPCKMM_00558	1.69e-174	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MEGPCKMM_00559	8.13e-59	-	-	-	-	-	-	-	-
MEGPCKMM_00560	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEGPCKMM_00561	1.73e-248	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
MEGPCKMM_00562	2.64e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
MEGPCKMM_00563	2.39e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEGPCKMM_00564	1.03e-156	-	-	-	-	-	-	-	-
MEGPCKMM_00565	1.08e-144	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MEGPCKMM_00566	4.3e-40	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MEGPCKMM_00567	3.18e-181	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEGPCKMM_00568	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
MEGPCKMM_00569	1.08e-119	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MEGPCKMM_00570	6.62e-176	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
MEGPCKMM_00571	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
MEGPCKMM_00572	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MEGPCKMM_00573	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEGPCKMM_00574	1.62e-205	-	-	-	P	-	-	-	Cation efflux family
MEGPCKMM_00575	8.36e-283	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
MEGPCKMM_00576	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00577	8.95e-94	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MEGPCKMM_00578	4.08e-62	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MEGPCKMM_00579	7.44e-155	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEGPCKMM_00580	1.47e-203	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MEGPCKMM_00581	1.17e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
MEGPCKMM_00582	0.0	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
MEGPCKMM_00583	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
MEGPCKMM_00584	3.36e-42	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MEGPCKMM_00585	3.96e-253	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
MEGPCKMM_00586	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00587	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00588	1.27e-291	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00589	1.12e-209	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MEGPCKMM_00590	5.91e-297	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00591	9.92e-149	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEGPCKMM_00592	2.29e-186	-	-	-	M	-	-	-	Mechanosensitive ion channel
MEGPCKMM_00593	1.65e-236	-	-	-	S	-	-	-	CAAX protease self-immunity
MEGPCKMM_00594	3.07e-178	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
MEGPCKMM_00596	2.54e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MEGPCKMM_00597	1.02e-202	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MEGPCKMM_00598	1.57e-202	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MEGPCKMM_00599	4.71e-316	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEGPCKMM_00600	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
MEGPCKMM_00601	5.98e-55	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
MEGPCKMM_00602	8.41e-165	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEGPCKMM_00603	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEGPCKMM_00604	1.96e-186	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
MEGPCKMM_00605	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MEGPCKMM_00608	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEGPCKMM_00609	3.59e-37	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEGPCKMM_00610	8.61e-54	yjbD	-	-	S	-	-	-	YjbD family (DUF3811)
MEGPCKMM_00611	6.21e-58	-	-	-	L	ko:K07483	-	ko00000	transposase activity
MEGPCKMM_00612	5.27e-195	-	-	-	S	-	-	-	Protein of unknown function DUF262
MEGPCKMM_00613	9.39e-149	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MEGPCKMM_00614	2.19e-271	-	-	-	T	-	-	-	Histidine kinase
MEGPCKMM_00615	1.62e-236	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00616	1.71e-301	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MEGPCKMM_00617	3.98e-295	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MEGPCKMM_00618	6.82e-254	-	1.4.1.12, 1.4.1.26	-	S	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	ko00000,ko00001,ko01000	Dihydrodipicolinate reductase, N-terminus
MEGPCKMM_00620	3.69e-184	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
MEGPCKMM_00621	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MEGPCKMM_00622	4.34e-247	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEGPCKMM_00623	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
MEGPCKMM_00624	8.42e-156	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEGPCKMM_00625	1.92e-144	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MEGPCKMM_00626	6.75e-113	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEGPCKMM_00627	1.78e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
MEGPCKMM_00628	8.14e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEGPCKMM_00629	2.43e-147	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MEGPCKMM_00631	1.82e-160	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEGPCKMM_00632	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEGPCKMM_00633	3.49e-247	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MEGPCKMM_00634	7.66e-127	-	-	-	-	-	-	-	-
MEGPCKMM_00635	1.73e-178	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MEGPCKMM_00636	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
MEGPCKMM_00637	7.37e-259	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MEGPCKMM_00638	8.16e-167	-	-	-	-	-	-	-	-
MEGPCKMM_00639	2.66e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEGPCKMM_00640	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MEGPCKMM_00641	1.21e-288	-	2.4.1.345	GT4	M	ko:K08256	-	ko00000,ko01000,ko01003	Glycosyl transferase 4-like domain
MEGPCKMM_00642	5.36e-282	-	-	-	G	-	-	-	Major Facilitator Superfamily
MEGPCKMM_00644	2.31e-56	-	-	-	G	-	-	-	Major facilitator superfamily
MEGPCKMM_00645	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MEGPCKMM_00646	2.47e-222	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
MEGPCKMM_00647	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MEGPCKMM_00648	9.9e-274	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
MEGPCKMM_00649	3.68e-312	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
MEGPCKMM_00650	1.42e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
MEGPCKMM_00651	4.9e-108	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MEGPCKMM_00652	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEGPCKMM_00653	4.86e-134	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEGPCKMM_00654	2.68e-232	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
MEGPCKMM_00655	6.49e-304	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEGPCKMM_00656	3.75e-155	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00657	1.09e-288	-	-	-	S	-	-	-	Peptidase dimerisation domain
MEGPCKMM_00658	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MEGPCKMM_00659	2.17e-43	-	-	-	-	-	-	-	-
MEGPCKMM_00660	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
MEGPCKMM_00661	6.98e-224	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEGPCKMM_00662	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
MEGPCKMM_00663	6.03e-306	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEGPCKMM_00664	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MEGPCKMM_00665	3.08e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEGPCKMM_00666	5.41e-160	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEGPCKMM_00667	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEGPCKMM_00670	2.54e-311	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MEGPCKMM_00671	0.0	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MEGPCKMM_00672	1.06e-192	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MEGPCKMM_00673	2.13e-157	safC	-	-	S	-	-	-	O-methyltransferase
MEGPCKMM_00674	1.36e-234	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MEGPCKMM_00675	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
MEGPCKMM_00676	1.44e-277	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
MEGPCKMM_00677	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
MEGPCKMM_00678	1.89e-114	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
MEGPCKMM_00679	9.84e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MEGPCKMM_00680	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
MEGPCKMM_00682	0.0	ykoD	-	-	P	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MEGPCKMM_00683	1.68e-136	ecfT	-	-	P	ko:K02008,ko:K16783,ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
MEGPCKMM_00684	2.32e-219	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEGPCKMM_00685	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MEGPCKMM_00686	3.72e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MEGPCKMM_00687	0.0	-	-	-	T	-	-	-	Histidine kinase
MEGPCKMM_00688	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
MEGPCKMM_00689	4.3e-186	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEGPCKMM_00690	2.17e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEGPCKMM_00691	1.32e-76	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
MEGPCKMM_00692	9.64e-47	-	-	-	-	-	-	-	-
MEGPCKMM_00693	1.66e-273	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
MEGPCKMM_00694	0.0	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
MEGPCKMM_00695	2.85e-255	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MEGPCKMM_00696	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
MEGPCKMM_00697	1.53e-189	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGPCKMM_00698	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MEGPCKMM_00699	2.17e-247	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEGPCKMM_00700	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MEGPCKMM_00701	2.15e-22	M1-966	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MEGPCKMM_00702	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEGPCKMM_00703	9.91e-189	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MEGPCKMM_00704	5.42e-232	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
MEGPCKMM_00705	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEGPCKMM_00706	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
MEGPCKMM_00707	6.85e-54	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
MEGPCKMM_00708	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
MEGPCKMM_00709	3.72e-105	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MEGPCKMM_00710	1.2e-116	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MEGPCKMM_00712	7.43e-130	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
MEGPCKMM_00713	8.43e-94	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	(ABC) transporter
MEGPCKMM_00714	2.88e-43	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MEGPCKMM_00715	0.0	cstA	-	-	T	ko:K06200	-	ko00000	5TM C-terminal transporter carbon starvation CstA
MEGPCKMM_00716	5.3e-22	-	-	-	S	-	-	-	Selenoprotein, putative
MEGPCKMM_00717	9.99e-300	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MEGPCKMM_00718	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
MEGPCKMM_00719	7.24e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MEGPCKMM_00720	3.18e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEGPCKMM_00721	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEGPCKMM_00723	3.28e-165	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00724	1.14e-224	-	-	-	P	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
MEGPCKMM_00725	3.38e-209	-	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_00726	8.66e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEGPCKMM_00727	3.48e-128	-	-	-	D	-	-	-	Septum formation initiator
MEGPCKMM_00728	2.96e-144	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
MEGPCKMM_00729	2.94e-238	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MEGPCKMM_00731	1.24e-136	-	-	-	-	-	-	-	-
MEGPCKMM_00732	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
MEGPCKMM_00733	2.24e-97	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
MEGPCKMM_00734	3.4e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEGPCKMM_00735	6.93e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MEGPCKMM_00736	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEGPCKMM_00737	5.33e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MEGPCKMM_00738	1.17e-313	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
MEGPCKMM_00739	8.99e-234	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
MEGPCKMM_00740	0.0	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
MEGPCKMM_00741	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
MEGPCKMM_00742	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_00743	1.6e-72	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MEGPCKMM_00744	1.75e-197	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
MEGPCKMM_00745	3.71e-187	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
MEGPCKMM_00746	8.38e-258	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEGPCKMM_00747	3.21e-168	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
MEGPCKMM_00748	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MEGPCKMM_00749	1.02e-132	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
MEGPCKMM_00750	7.88e-116	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MEGPCKMM_00751	2.27e-185	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MEGPCKMM_00752	4.24e-217	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00753	1.26e-236	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MEGPCKMM_00754	3.33e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEGPCKMM_00755	4.47e-315	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MEGPCKMM_00756	1.4e-152	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEGPCKMM_00757	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEGPCKMM_00758	5.79e-230	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
MEGPCKMM_00759	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
MEGPCKMM_00761	6.77e-153	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MEGPCKMM_00762	7.75e-158	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
MEGPCKMM_00764	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEGPCKMM_00765	3.04e-235	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
MEGPCKMM_00766	3.06e-158	-	-	-	L	-	-	-	NUDIX domain
MEGPCKMM_00767	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MEGPCKMM_00768	1.05e-295	-	-	-	-	-	-	-	-
MEGPCKMM_00770	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEGPCKMM_00771	4.94e-297	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEGPCKMM_00772	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
MEGPCKMM_00773	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MEGPCKMM_00774	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MEGPCKMM_00775	4.41e-92	-	-	-	K	-	-	-	sequence-specific DNA binding
MEGPCKMM_00776	5.18e-228	-	-	-	L	ko:K07481	-	ko00000	Transposase domain (DUF772)
MEGPCKMM_00777	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
MEGPCKMM_00778	8.85e-85	-	-	-	S	ko:K07133	-	ko00000	AAA domain
MEGPCKMM_00779	3.03e-140	-	-	-	F	-	-	-	adenylate kinase activity
MEGPCKMM_00780	1.82e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MEGPCKMM_00781	6.73e-207	-	-	-	E	-	-	-	-acetyltransferase
MEGPCKMM_00782	1.23e-67	-	4.2.99.21	-	E	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Chorismate mutase type II
MEGPCKMM_00783	3.44e-182	-	-	-	-	-	-	-	-
MEGPCKMM_00784	1.88e-214	add1	3.5.4.4	-	F	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MEGPCKMM_00785	5.23e-244	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEGPCKMM_00786	1.42e-86	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MEGPCKMM_00787	2.02e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00788	1.89e-133	-	-	-	S	-	-	-	ABC-2 family transporter protein
MEGPCKMM_00789	1.63e-110	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MEGPCKMM_00790	1.07e-181	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MEGPCKMM_00791	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
MEGPCKMM_00792	5.4e-239	-	-	-	K	-	-	-	TRANSCRIPTIONal
MEGPCKMM_00793	1.51e-226	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MEGPCKMM_00794	6.73e-26	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MEGPCKMM_00795	1.5e-151	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MEGPCKMM_00796	0.0	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
MEGPCKMM_00797	8.71e-119	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEGPCKMM_00798	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MEGPCKMM_00799	3.61e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEGPCKMM_00800	2.01e-81	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MEGPCKMM_00801	7.34e-165	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MEGPCKMM_00802	1.31e-84	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MEGPCKMM_00803	6.54e-46	-	-	-	-	-	-	-	-
MEGPCKMM_00804	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEGPCKMM_00805	3.78e-112	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEGPCKMM_00806	2.13e-264	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEGPCKMM_00808	1.45e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEGPCKMM_00809	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MEGPCKMM_00810	2.03e-92	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MEGPCKMM_00811	1.64e-242	-	-	-	-	-	-	-	-
MEGPCKMM_00812	2.23e-105	-	-	-	-	-	-	-	-
MEGPCKMM_00813	1.78e-105	-	-	-	-	-	-	-	-
MEGPCKMM_00814	1.49e-286	-	-	-	-	-	-	-	-
MEGPCKMM_00815	6.74e-281	-	-	-	-	-	-	-	-
MEGPCKMM_00818	7.78e-125	-	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MEGPCKMM_00819	2.25e-109	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
MEGPCKMM_00820	4.16e-236	pulA	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MEGPCKMM_00821	3.78e-73	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
MEGPCKMM_00822	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEGPCKMM_00823	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MEGPCKMM_00824	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
MEGPCKMM_00825	8.08e-300	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
MEGPCKMM_00826	8.04e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MEGPCKMM_00827	2.17e-305	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEGPCKMM_00828	3.17e-135	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MEGPCKMM_00829	6.88e-121	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MEGPCKMM_00830	2.43e-284	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MEGPCKMM_00831	9.8e-171	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
MEGPCKMM_00832	2.75e-211	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
MEGPCKMM_00834	7.71e-185	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEGPCKMM_00835	2.19e-77	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MEGPCKMM_00836	1.28e-274	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
MEGPCKMM_00837	1.5e-134	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEGPCKMM_00838	0.0	corC	-	-	S	-	-	-	CBS domain
MEGPCKMM_00839	6.02e-232	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEGPCKMM_00840	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MEGPCKMM_00841	2.51e-258	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
MEGPCKMM_00842	4.73e-62	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
MEGPCKMM_00843	0.0	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MEGPCKMM_00844	2.54e-249	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MEGPCKMM_00845	6.37e-139	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MEGPCKMM_00846	2.14e-289	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
MEGPCKMM_00847	1.74e-179	-	-	-	S	-	-	-	UPF0126 domain
MEGPCKMM_00848	1.36e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MEGPCKMM_00849	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEGPCKMM_00850	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MEGPCKMM_00851	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
MEGPCKMM_00852	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MEGPCKMM_00853	1.11e-103	-	-	-	-	-	-	-	-
MEGPCKMM_00854	4.8e-114	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
MEGPCKMM_00855	2.02e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
MEGPCKMM_00856	1.41e-203	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00857	7.41e-254	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MEGPCKMM_00858	1.07e-127	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
MEGPCKMM_00859	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MEGPCKMM_00860	6.6e-206	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MEGPCKMM_00861	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MEGPCKMM_00862	1.33e-115	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
MEGPCKMM_00863	6.91e-242	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MEGPCKMM_00864	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MEGPCKMM_00865	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEGPCKMM_00866	1.68e-225	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
MEGPCKMM_00867	3.32e-202	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MEGPCKMM_00868	8.93e-241	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEGPCKMM_00869	5.35e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEGPCKMM_00870	6.8e-104	ypeA	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
MEGPCKMM_00871	1.25e-66	-	-	-	L	-	-	-	NUDIX domain
MEGPCKMM_00872	1.2e-76	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MEGPCKMM_00873	9.71e-232	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MEGPCKMM_00874	1.23e-243	-	-	-	S	-	-	-	Protein conserved in bacteria
MEGPCKMM_00875	5.22e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MEGPCKMM_00876	7.4e-223	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MEGPCKMM_00877	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MEGPCKMM_00878	5e-140	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
MEGPCKMM_00879	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEGPCKMM_00880	2.09e-236	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEGPCKMM_00881	3.09e-187	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MEGPCKMM_00882	3.78e-249	-	-	-	P	-	-	-	Cation efflux family
MEGPCKMM_00883	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MEGPCKMM_00884	1.93e-157	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MEGPCKMM_00885	1.57e-127	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
MEGPCKMM_00886	2.31e-230	-	-	-	-	-	-	-	-
MEGPCKMM_00888	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEGPCKMM_00889	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEGPCKMM_00890	1.28e-225	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
MEGPCKMM_00891	1.72e-224	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MEGPCKMM_00892	2.67e-224	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MEGPCKMM_00893	2.34e-284	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
MEGPCKMM_00894	2.06e-194	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEGPCKMM_00895	2.87e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
MEGPCKMM_00896	7.54e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MEGPCKMM_00897	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
MEGPCKMM_00898	1.01e-117	-	-	-	K	-	-	-	helix_turn_helix ASNC type
MEGPCKMM_00899	4.1e-293	-	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K00841,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MEGPCKMM_00900	3.06e-109	-	-	-	S	-	-	-	PFAM Pentapeptide repeats (8 copies)
MEGPCKMM_00901	9.8e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MEGPCKMM_00902	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
MEGPCKMM_00903	2.8e-256	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEGPCKMM_00904	2.49e-279	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEGPCKMM_00905	4.59e-53	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MEGPCKMM_00906	2.9e-264	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MEGPCKMM_00907	1.4e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
MEGPCKMM_00908	3.73e-104	-	-	-	I	-	-	-	Sterol carrier protein
MEGPCKMM_00909	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEGPCKMM_00910	9.18e-49	-	-	-	-	-	-	-	-
MEGPCKMM_00911	1.76e-164	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MEGPCKMM_00912	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
MEGPCKMM_00913	2.13e-46	crgA	-	-	D	-	-	-	Involved in cell division
MEGPCKMM_00914	1.4e-177	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MEGPCKMM_00915	1.07e-285	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MEGPCKMM_00916	7.93e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
MEGPCKMM_00917	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MEGPCKMM_00918	1.37e-248	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MEGPCKMM_00919	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MEGPCKMM_00920	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MEGPCKMM_00921	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MEGPCKMM_00922	2.44e-94	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MEGPCKMM_00923	1.83e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
MEGPCKMM_00924	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MEGPCKMM_00925	5.05e-161	-	-	-	EG	-	-	-	EamA-like transporter family
MEGPCKMM_00926	1.54e-271	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
MEGPCKMM_00927	3.36e-77	-	-	-	-	-	-	-	-
MEGPCKMM_00928	1.39e-229	rrmA	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MEGPCKMM_00929	4.12e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
MEGPCKMM_00930	4.74e-48	-	-	-	S	-	-	-	Transglycosylase associated protein
MEGPCKMM_00932	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
MEGPCKMM_00933	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MEGPCKMM_00934	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
MEGPCKMM_00935	6.47e-149	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MEGPCKMM_00936	0.0	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
MEGPCKMM_00937	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEGPCKMM_00939	1.98e-232	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MEGPCKMM_00940	6.74e-271	-	-	-	V	-	-	-	Beta-lactamase
MEGPCKMM_00941	8.61e-158	-	-	-	E	-	-	-	SOS response associated peptidase (SRAP)
MEGPCKMM_00942	4.63e-293	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
MEGPCKMM_00943	2.14e-14	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MEGPCKMM_00944	8.74e-69	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MEGPCKMM_00945	2.39e-113	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEGPCKMM_00946	0.0	-	-	-	S	-	-	-	cellulose binding
MEGPCKMM_00947	1.87e-181	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MEGPCKMM_00948	1.13e-111	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
MEGPCKMM_00949	2.08e-244	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
MEGPCKMM_00950	5.51e-206	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MEGPCKMM_00951	1.43e-250	-	1.1.1.91	-	C	ko:K05882	-	ko00000,ko01000	Aldo/keto reductase family
MEGPCKMM_00952	2.27e-05	-	-	-	I	-	-	-	acetylesterase activity
MEGPCKMM_00953	0.0	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
MEGPCKMM_00954	1.47e-120	-	-	-	C	-	-	-	Flavodoxin
MEGPCKMM_00955	1.47e-51	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MEGPCKMM_00956	1.97e-111	-	-	-	C	-	-	-	Flavodoxin
MEGPCKMM_00957	3.29e-189	-	-	-	GM	-	-	-	NmrA-like family
MEGPCKMM_00958	7.83e-262	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MEGPCKMM_00959	2.86e-213	-	-	-	K	-	-	-	LysR substrate binding domain
MEGPCKMM_00960	0.0	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MEGPCKMM_00961	8.45e-249	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MEGPCKMM_00962	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEGPCKMM_00963	3.73e-224	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEGPCKMM_00964	7.85e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEGPCKMM_00965	2.82e-306	-	-	-	U	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MEGPCKMM_00966	6.84e-210	livM	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MEGPCKMM_00967	1.67e-202	-	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
MEGPCKMM_00968	6.62e-194	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00969	1.73e-287	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
MEGPCKMM_00970	1e-244	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MEGPCKMM_00971	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
MEGPCKMM_00972	0.0	-	-	-	G	-	-	-	Transporter major facilitator family protein
MEGPCKMM_00973	9.6e-144	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
MEGPCKMM_00974	1.8e-101	accBC3	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
MEGPCKMM_00975	3.05e-234	-	-	-	S	-	-	-	Domain of unknown function (DUF4392)
MEGPCKMM_00976	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
MEGPCKMM_00977	5.95e-121	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MEGPCKMM_00978	2.26e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
MEGPCKMM_00980	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MEGPCKMM_00981	1.53e-258	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MEGPCKMM_00983	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
MEGPCKMM_00984	3.67e-281	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MEGPCKMM_00985	0.0	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MEGPCKMM_00986	2.28e-175	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
MEGPCKMM_00987	5.1e-240	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MEGPCKMM_00988	1.8e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MEGPCKMM_00989	3.02e-171	-	-	-	-	-	-	-	-
MEGPCKMM_00990	5.24e-34	-	-	-	-	-	-	-	-
MEGPCKMM_00991	0.0	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MEGPCKMM_00992	8.53e-172	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_00993	1.42e-187	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MEGPCKMM_00994	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
MEGPCKMM_00996	5.82e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MEGPCKMM_00997	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MEGPCKMM_00998	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MEGPCKMM_00999	1.08e-43	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
MEGPCKMM_01001	0.0	-	-	-	M	-	-	-	MacB-like periplasmic core domain
MEGPCKMM_01002	8.06e-96	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEGPCKMM_01003	7.97e-137	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEGPCKMM_01004	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MEGPCKMM_01005	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MEGPCKMM_01006	0.0	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MEGPCKMM_01007	5.42e-158	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MEGPCKMM_01008	6.76e-151	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MEGPCKMM_01009	1.34e-98	-	-	-	-	-	-	-	-
MEGPCKMM_01010	1.16e-292	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
MEGPCKMM_01011	2.75e-136	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_01012	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MEGPCKMM_01013	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MEGPCKMM_01014	2.58e-139	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
MEGPCKMM_01015	7.69e-171	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MEGPCKMM_01016	0.0	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_01017	2.93e-230	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MEGPCKMM_01018	6.48e-213	-	-	-	S	-	-	-	esterase of the alpha-beta hydrolase superfamily
MEGPCKMM_01019	9.61e-43	-	-	-	K	-	-	-	transcriptional regulator
MEGPCKMM_01020	6.61e-147	-	-	-	-	-	-	-	-
MEGPCKMM_01022	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MEGPCKMM_01023	7.53e-156	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEGPCKMM_01024	1.95e-301	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEGPCKMM_01025	1.79e-300	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
MEGPCKMM_01026	6.28e-73	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
MEGPCKMM_01027	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
MEGPCKMM_01028	3.38e-51	-	-	-	K	-	-	-	sequence-specific DNA binding
MEGPCKMM_01029	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MEGPCKMM_01030	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
MEGPCKMM_01031	6.15e-183	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MEGPCKMM_01032	3.85e-69	-	-	-	S	-	-	-	granule-associated protein
MEGPCKMM_01033	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
MEGPCKMM_01034	3.02e-254	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MEGPCKMM_01035	5.67e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEGPCKMM_01036	2.45e-168	-	-	-	-	-	-	-	-
MEGPCKMM_01037	5.22e-262	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
MEGPCKMM_01038	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MEGPCKMM_01039	3.59e-95	-	-	-	D	-	-	-	bacterial-type flagellum organization
MEGPCKMM_01040	2.01e-291	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
MEGPCKMM_01041	3.09e-151	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
MEGPCKMM_01042	3.93e-143	-	-	-	U	-	-	-	Type II secretion system (T2SS), protein F
MEGPCKMM_01043	4.93e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
MEGPCKMM_01044	5.66e-74	-	-	-	U	-	-	-	TadE-like protein
MEGPCKMM_01045	6.12e-98	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
MEGPCKMM_01046	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
MEGPCKMM_01047	8.17e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEGPCKMM_01048	2.52e-173	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MEGPCKMM_01049	5.79e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MEGPCKMM_01050	2.38e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEGPCKMM_01051	1.7e-155	-	-	-	-	-	-	-	-
MEGPCKMM_01052	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MEGPCKMM_01053	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
MEGPCKMM_01054	2.86e-274	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Myo-inositol-1-phosphate synthase
MEGPCKMM_01056	4.9e-281	-	-	-	I	-	-	-	PAP2 superfamily
MEGPCKMM_01057	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEGPCKMM_01058	2.72e-142	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEGPCKMM_01059	1.16e-285	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MEGPCKMM_01060	6.8e-181	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MEGPCKMM_01061	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MEGPCKMM_01062	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MEGPCKMM_01063	3.43e-281	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MEGPCKMM_01064	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
MEGPCKMM_01065	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
MEGPCKMM_01066	5.83e-255	-	-	-	S	-	-	-	Protein conserved in bacteria
MEGPCKMM_01067	1.74e-130	-	-	-	S	-	-	-	GtrA-like protein
MEGPCKMM_01068	2.38e-224	-	-	-	-	-	-	-	-
MEGPCKMM_01069	1.51e-159	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MEGPCKMM_01070	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MEGPCKMM_01071	6.14e-110	-	-	-	-	-	-	-	-
MEGPCKMM_01072	0.0	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
MEGPCKMM_01073	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
MEGPCKMM_01074	1.13e-132	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
MEGPCKMM_01075	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
MEGPCKMM_01076	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
MEGPCKMM_01077	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
MEGPCKMM_01078	8.76e-261	-	-	-	S	-	-	-	EpsG family
MEGPCKMM_01079	5.53e-205	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
MEGPCKMM_01080	6.67e-237	-	-	-	S	-	-	-	Glycosyl transferase family 2
MEGPCKMM_01081	1.84e-119	-	-	-	M	-	-	-	Glycosyltransferase family 28 C-terminal domain
MEGPCKMM_01082	6.41e-111	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
MEGPCKMM_01083	2.14e-282	-	-	-	M	-	-	-	epimerase dehydratase
MEGPCKMM_01084	2.15e-153	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MEGPCKMM_01085	2.31e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MEGPCKMM_01086	1.3e-174	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
MEGPCKMM_01087	6.59e-310	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MEGPCKMM_01088	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MEGPCKMM_01089	2.01e-65	-	-	-	-	-	-	-	-
MEGPCKMM_01090	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MEGPCKMM_01091	4.92e-208	-	-	-	S	-	-	-	Glycosyl transferase family 2
MEGPCKMM_01092	1.53e-252	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MEGPCKMM_01093	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MEGPCKMM_01094	5.09e-302	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
MEGPCKMM_01095	3.61e-234	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
MEGPCKMM_01096	1.34e-210	-	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase like family 2
MEGPCKMM_01097	9.26e-187	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MEGPCKMM_01098	6.81e-220	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
MEGPCKMM_01099	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_01100	4.03e-245	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
MEGPCKMM_01101	6.8e-219	-	-	-	S	-	-	-	Glycosyl transferase family 2
MEGPCKMM_01102	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MEGPCKMM_01103	4.52e-237	-	-	-	M	-	-	-	Glycosyl transferase family 2
MEGPCKMM_01104	1.28e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEGPCKMM_01105	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEGPCKMM_01106	8.58e-218	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MEGPCKMM_01107	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
MEGPCKMM_01108	3.45e-239	-	-	-	M	-	-	-	Glycosyl transferase family 2
MEGPCKMM_01109	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
MEGPCKMM_01110	1.57e-100	-	-	-	-	-	-	-	-
MEGPCKMM_01111	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MEGPCKMM_01112	3.66e-241	-	-	-	S	ko:K21688	-	ko00000	G5
MEGPCKMM_01113	1.18e-86	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
MEGPCKMM_01114	1.17e-109	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
MEGPCKMM_01115	3.34e-220	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MEGPCKMM_01116	2.11e-273	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
MEGPCKMM_01117	5.74e-94	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MEGPCKMM_01118	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
MEGPCKMM_01119	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
MEGPCKMM_01120	1.06e-220	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MEGPCKMM_01121	1.84e-28	-	-	-	-	-	-	-	-
MEGPCKMM_01122	5.69e-105	-	-	-	J	-	-	-	TM2 domain
MEGPCKMM_01123	5.28e-283	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
MEGPCKMM_01124	1.64e-178	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MEGPCKMM_01125	0.0	pon1	-	-	M	-	-	-	Transglycosylase
MEGPCKMM_01126	2.6e-282	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MEGPCKMM_01127	2.16e-282	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MEGPCKMM_01128	9.89e-143	ppm1	2.4.1.83	GT2	S	ko:K00721	ko00510,ko01100,map00510,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase family 2
MEGPCKMM_01129	5.19e-184	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MEGPCKMM_01130	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
MEGPCKMM_01131	3.52e-295	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
MEGPCKMM_01133	1.45e-192	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MEGPCKMM_01134	1.69e-57	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MEGPCKMM_01135	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MEGPCKMM_01136	3.3e-165	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEGPCKMM_01137	5.51e-239	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
MEGPCKMM_01138	2.17e-68	-	-	-	-	-	-	-	-
MEGPCKMM_01139	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGPCKMM_01140	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGPCKMM_01141	1.49e-138	-	-	-	T	-	-	-	Forkhead associated domain
MEGPCKMM_01142	5.62e-135	-	-	-	B	-	-	-	Belongs to the OprB family
MEGPCKMM_01143	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
MEGPCKMM_01144	3.4e-266	-	-	-	S	-	-	-	Protein of unknown function DUF58
MEGPCKMM_01145	9.88e-163	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MEGPCKMM_01146	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
MEGPCKMM_01147	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MEGPCKMM_01148	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
MEGPCKMM_01149	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
MEGPCKMM_01150	2.04e-171	-	-	-	K	-	-	-	-acetyltransferase
MEGPCKMM_01151	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
MEGPCKMM_01152	7.91e-173	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEGPCKMM_01153	3.72e-212	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEGPCKMM_01154	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEGPCKMM_01155	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
MEGPCKMM_01156	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEGPCKMM_01157	1.64e-162	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEGPCKMM_01158	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MEGPCKMM_01159	0.0	-	-	-	S	-	-	-	zinc finger
MEGPCKMM_01160	1.34e-130	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MEGPCKMM_01161	2.09e-217	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
MEGPCKMM_01162	5.11e-165	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
MEGPCKMM_01164	7.29e-244	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
MEGPCKMM_01165	4.21e-60	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEGPCKMM_01166	1.04e-305	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEGPCKMM_01167	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
MEGPCKMM_01168	2.07e-190	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEGPCKMM_01169	3.76e-183	-	-	-	-	-	-	-	-
MEGPCKMM_01170	5.83e-78	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MEGPCKMM_01171	8.85e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MEGPCKMM_01172	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
MEGPCKMM_01173	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
MEGPCKMM_01174	0.0	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEGPCKMM_01175	7.49e-24	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR associated protein Cas2
MEGPCKMM_01176	5.26e-284	-	-	-	S	ko:K19131	-	ko00000,ko02048	CRISPR-associated protein GSU0053 (Cas_GSU0053)
MEGPCKMM_01177	0.0	-	-	-	-	ko:K19132	-	ko00000,ko02048	-
MEGPCKMM_01178	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase Cas3
MEGPCKMM_01179	4.02e-265	-	-	-	-	ko:K19133	-	ko00000,ko02048	-
MEGPCKMM_01180	6.34e-66	-	-	-	-	-	-	-	-
MEGPCKMM_01183	1.31e-129	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MEGPCKMM_01184	2.28e-132	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MEGPCKMM_01185	6.41e-127	-	-	-	K	-	-	-	MarR family
MEGPCKMM_01186	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MEGPCKMM_01187	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MEGPCKMM_01188	2.3e-22	-	-	-	-	-	-	-	-
MEGPCKMM_01189	5.39e-62	-	-	-	-	-	-	-	-
MEGPCKMM_01190	1.7e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MEGPCKMM_01191	3.48e-33	-	-	-	-	-	-	-	-
MEGPCKMM_01192	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEGPCKMM_01193	8.06e-315	-	-	-	S	-	-	-	COG1512 Beta-propeller domains of methanol dehydrogenase type
MEGPCKMM_01194	3.33e-149	pspA	-	-	KT	ko:K03969	-	ko00000	PspA/IM30 family
MEGPCKMM_01195	0.0	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
MEGPCKMM_01196	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MEGPCKMM_01197	3.18e-41	-	-	-	-	-	-	-	-
MEGPCKMM_01198	1.13e-150	-	-	-	-	-	-	-	-
MEGPCKMM_01199	0.0	lysI	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
MEGPCKMM_01200	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
MEGPCKMM_01203	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
MEGPCKMM_01204	3.31e-158	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
MEGPCKMM_01205	3.99e-47	-	-	-	-	-	-	-	-
MEGPCKMM_01206	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MEGPCKMM_01207	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MEGPCKMM_01208	3.81e-133	-	-	-	-	-	-	-	-
MEGPCKMM_01209	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEGPCKMM_01210	2.68e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
MEGPCKMM_01211	5.41e-204	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
MEGPCKMM_01212	4.59e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
MEGPCKMM_01213	2.11e-153	-	-	-	-	-	-	-	-
MEGPCKMM_01214	0.0	dppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEGPCKMM_01215	9.25e-220	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MEGPCKMM_01216	1.48e-199	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01217	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MEGPCKMM_01218	1.44e-228	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
MEGPCKMM_01219	4.76e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEGPCKMM_01220	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MEGPCKMM_01221	3.14e-54	-	-	-	-	-	-	-	-
MEGPCKMM_01222	7.85e-270	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
MEGPCKMM_01223	6.3e-277	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MEGPCKMM_01224	2.34e-118	-	-	-	-	-	-	-	-
MEGPCKMM_01225	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
MEGPCKMM_01226	0.0	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
MEGPCKMM_01227	1.01e-200	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
MEGPCKMM_01228	1.55e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MEGPCKMM_01229	9.9e-214	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
MEGPCKMM_01230	1.63e-82	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEGPCKMM_01231	1.79e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
MEGPCKMM_01232	2.25e-136	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEGPCKMM_01233	1.68e-193	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
MEGPCKMM_01234	1.3e-264	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEGPCKMM_01235	3.2e-116	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEGPCKMM_01236	4.77e-229	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MEGPCKMM_01237	3.12e-253	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MEGPCKMM_01238	1.32e-72	-	-	-	-	-	-	-	-
MEGPCKMM_01239	2.85e-169	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEGPCKMM_01240	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEGPCKMM_01241	2e-255	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
MEGPCKMM_01242	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
MEGPCKMM_01243	5.94e-149	-	-	-	KT	-	-	-	cheY-homologous receiver domain
MEGPCKMM_01244	2.34e-248	-	-	-	T	-	-	-	Histidine kinase
MEGPCKMM_01245	3.55e-192	-	-	-	-	-	-	-	-
MEGPCKMM_01246	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
MEGPCKMM_01247	6.13e-127	-	-	-	F	-	-	-	NUDIX domain
MEGPCKMM_01248	1.51e-284	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MEGPCKMM_01249	2.02e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MEGPCKMM_01250	6.33e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEGPCKMM_01251	3.23e-271	int8	-	-	L	-	-	-	Phage integrase family
MEGPCKMM_01253	0.00013	-	-	-	L	-	-	-	Helix-turn-helix domain
MEGPCKMM_01257	3.06e-39	-	-	-	-	-	-	-	-
MEGPCKMM_01258	4.49e-291	-	-	-	T	-	-	-	AAA domain
MEGPCKMM_01263	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
MEGPCKMM_01266	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEGPCKMM_01267	3.5e-272	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01268	1.98e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01269	5.75e-76	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MEGPCKMM_01270	3.14e-200	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MEGPCKMM_01271	2.95e-301	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
MEGPCKMM_01272	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MEGPCKMM_01273	2.95e-206	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEGPCKMM_01274	0.0	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
MEGPCKMM_01275	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEGPCKMM_01276	1.21e-267	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEGPCKMM_01277	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEGPCKMM_01278	9.34e-204	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEGPCKMM_01279	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
MEGPCKMM_01280	3.19e-119	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MEGPCKMM_01281	2.11e-249	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEGPCKMM_01282	5.36e-111	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MEGPCKMM_01283	0.0	-	-	-	L	-	-	-	DNA helicase
MEGPCKMM_01284	1.59e-289	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MEGPCKMM_01285	1.85e-125	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEGPCKMM_01286	3.77e-14	-	-	-	M	-	-	-	LysM domain
MEGPCKMM_01287	1.06e-165	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEGPCKMM_01288	2.23e-212	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEGPCKMM_01289	3.25e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MEGPCKMM_01290	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEGPCKMM_01291	1.27e-150	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
MEGPCKMM_01292	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
MEGPCKMM_01293	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MEGPCKMM_01294	1.28e-230	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
MEGPCKMM_01295	3.66e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
MEGPCKMM_01296	2.09e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEGPCKMM_01297	4.58e-167	-	-	-	-	-	-	-	-
MEGPCKMM_01298	2.09e-143	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
MEGPCKMM_01299	2.17e-287	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MEGPCKMM_01300	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MEGPCKMM_01301	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
MEGPCKMM_01303	5.2e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MEGPCKMM_01304	1.34e-127	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEGPCKMM_01305	7.28e-149	-	-	-	V	-	-	-	DivIVA protein
MEGPCKMM_01306	1.18e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MEGPCKMM_01307	2.22e-103	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEGPCKMM_01308	7.23e-283	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEGPCKMM_01309	3.31e-316	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEGPCKMM_01310	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
MEGPCKMM_01311	7.5e-125	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEGPCKMM_01312	0.0	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MEGPCKMM_01313	7.04e-79	-	-	-	S	-	-	-	Thiamine-binding protein
MEGPCKMM_01314	3.28e-257	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MEGPCKMM_01315	9.04e-316	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
MEGPCKMM_01316	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MEGPCKMM_01317	7.44e-190	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01318	3.8e-264	-	-	-	P	-	-	-	NMT1/THI5 like
MEGPCKMM_01319	4.16e-299	-	-	-	F	-	-	-	nucleoside hydrolase
MEGPCKMM_01321	5.72e-195	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEGPCKMM_01322	3.68e-170	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MEGPCKMM_01323	0.0	-	-	-	I	-	-	-	acetylesterase activity
MEGPCKMM_01324	1.48e-291	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MEGPCKMM_01325	5.92e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MEGPCKMM_01326	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
MEGPCKMM_01328	1.94e-105	-	-	-	-	-	-	-	-
MEGPCKMM_01329	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
MEGPCKMM_01330	9.43e-233	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MEGPCKMM_01331	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MEGPCKMM_01332	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MEGPCKMM_01333	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
MEGPCKMM_01334	1.45e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
MEGPCKMM_01335	1.14e-213	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
MEGPCKMM_01336	3.37e-156	-	-	-	S	-	-	-	Vitamin K epoxide reductase
MEGPCKMM_01337	7.78e-223	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MEGPCKMM_01338	3.84e-186	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MEGPCKMM_01339	1.21e-207	-	-	-	S	-	-	-	Patatin-like phospholipase
MEGPCKMM_01340	7.34e-197	hflK	-	-	O	-	-	-	prohibitin homologues
MEGPCKMM_01341	9.92e-211	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MEGPCKMM_01342	2.41e-204	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
MEGPCKMM_01343	3.77e-157	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01344	1.29e-145	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01345	2.49e-295	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MEGPCKMM_01346	3.64e-142	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
MEGPCKMM_01347	3e-280	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEGPCKMM_01348	8.77e-208	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
MEGPCKMM_01349	1.42e-244	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEGPCKMM_01350	1.07e-165	-	-	-	K	-	-	-	acetyltransferase
MEGPCKMM_01351	5.15e-134	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
MEGPCKMM_01352	0.0	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
MEGPCKMM_01353	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
MEGPCKMM_01354	2.59e-257	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
MEGPCKMM_01355	2.72e-187	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
MEGPCKMM_01356	1.43e-284	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MEGPCKMM_01357	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MEGPCKMM_01359	2.78e-237	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MEGPCKMM_01360	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
MEGPCKMM_01361	3.43e-206	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01362	1.35e-238	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01363	1.66e-308	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEGPCKMM_01364	2.57e-297	-	-	-	GK	-	-	-	ROK family
MEGPCKMM_01365	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
MEGPCKMM_01366	4.78e-110	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEGPCKMM_01367	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
MEGPCKMM_01368	3.82e-232	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MEGPCKMM_01369	2.47e-253	-	-	-	D	-	-	-	nuclear chromosome segregation
MEGPCKMM_01370	5.78e-143	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
MEGPCKMM_01371	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
MEGPCKMM_01372	3.62e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEGPCKMM_01373	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
MEGPCKMM_01374	6.27e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEGPCKMM_01375	1.41e-241	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
MEGPCKMM_01376	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MEGPCKMM_01377	3.47e-114	-	-	-	O	-	-	-	Thioredoxin
MEGPCKMM_01379	7.02e-285	rpfB	-	-	S	ko:K21688	-	ko00000	G5
MEGPCKMM_01380	1.13e-208	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEGPCKMM_01381	1.44e-227	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEGPCKMM_01382	1.51e-145	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MEGPCKMM_01383	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
MEGPCKMM_01384	1.51e-239	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
MEGPCKMM_01385	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_01386	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
MEGPCKMM_01387	2.29e-228	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEGPCKMM_01388	0.0	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MEGPCKMM_01389	2.2e-225	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MEGPCKMM_01390	1.82e-174	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MEGPCKMM_01391	4.13e-122	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
MEGPCKMM_01392	8.06e-234	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
MEGPCKMM_01393	9.33e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MEGPCKMM_01394	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEGPCKMM_01395	7.9e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEGPCKMM_01396	0.0	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEGPCKMM_01397	2.35e-117	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
MEGPCKMM_01398	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEGPCKMM_01399	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEGPCKMM_01400	2.65e-108	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
MEGPCKMM_01401	3.27e-279	-	-	-	V	-	-	-	VanZ like family
MEGPCKMM_01402	3.88e-207	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MEGPCKMM_01403	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MEGPCKMM_01404	4.42e-307	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
MEGPCKMM_01405	6.85e-218	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Glycosyl hydrolase family 26
MEGPCKMM_01406	1.39e-95	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEGPCKMM_01407	3.45e-68	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
MEGPCKMM_01410	4.87e-187	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
MEGPCKMM_01411	2.87e-101	-	-	-	-	-	-	-	-
MEGPCKMM_01412	6.65e-198	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MEGPCKMM_01413	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MEGPCKMM_01414	2.44e-191	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MEGPCKMM_01415	1.79e-214	-	-	-	-	-	-	-	-
MEGPCKMM_01416	5.12e-139	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
MEGPCKMM_01417	5.46e-136	-	-	-	-	-	-	-	-
MEGPCKMM_01418	3.27e-25	-	-	-	-	-	-	-	-
MEGPCKMM_01421	2.13e-75	-	-	-	S	-	-	-	MazG-like family
MEGPCKMM_01422	1.15e-31	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MEGPCKMM_01424	2.53e-243	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
MEGPCKMM_01425	2.61e-60	-	-	-	S	-	-	-	Type II restriction endonuclease EcoO109I
MEGPCKMM_01426	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_01427	1.94e-143	-	-	-	-	-	-	-	-
MEGPCKMM_01428	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_01429	0.0	-	-	-	-	-	-	-	-
MEGPCKMM_01430	1.06e-52	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MEGPCKMM_01431	5.7e-30	-	-	-	K	-	-	-	SpoVT / AbrB like domain
MEGPCKMM_01432	1.01e-86	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MEGPCKMM_01433	1.46e-210	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MEGPCKMM_01434	1.14e-30	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MEGPCKMM_01435	6.38e-154	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Aldo/keto reductase family
MEGPCKMM_01436	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MEGPCKMM_01437	4.75e-110	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
MEGPCKMM_01438	1.13e-26	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
MEGPCKMM_01439	1.92e-115	-	-	-	S	-	-	-	Domain of unknown function (DUF4234)
MEGPCKMM_01440	4.45e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MEGPCKMM_01441	3.76e-218	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MEGPCKMM_01442	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
MEGPCKMM_01443	9.03e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEGPCKMM_01444	8.13e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEGPCKMM_01445	5.36e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MEGPCKMM_01446	1.77e-124	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MEGPCKMM_01447	1.06e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEGPCKMM_01448	3.61e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MEGPCKMM_01449	6.82e-174	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
MEGPCKMM_01453	7.69e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MEGPCKMM_01454	7.84e-218	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
MEGPCKMM_01455	3.88e-251	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MEGPCKMM_01456	3.91e-200	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MEGPCKMM_01457	5.75e-244	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MEGPCKMM_01458	0.0	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
MEGPCKMM_01459	0.0	-	-	-	M	-	-	-	domain protein
MEGPCKMM_01460	4.56e-109	-	-	-	-	-	-	-	-
MEGPCKMM_01461	1.32e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
MEGPCKMM_01462	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEGPCKMM_01463	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
MEGPCKMM_01464	6.33e-148	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEGPCKMM_01465	7.8e-196	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
MEGPCKMM_01466	2.77e-176	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MEGPCKMM_01467	8.48e-198	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
MEGPCKMM_01468	4.42e-34	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEGPCKMM_01469	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEGPCKMM_01470	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEGPCKMM_01471	7.27e-252	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MEGPCKMM_01472	1.87e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
MEGPCKMM_01473	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
MEGPCKMM_01474	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MEGPCKMM_01475	0.0	-	-	-	S	-	-	-	domain protein
MEGPCKMM_01476	1.91e-83	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
MEGPCKMM_01477	1e-135	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
MEGPCKMM_01478	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEGPCKMM_01479	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MEGPCKMM_01480	4.39e-178	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEGPCKMM_01481	6.99e-177	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
MEGPCKMM_01482	3.16e-197	-	-	-	-	-	-	-	-
MEGPCKMM_01483	3.01e-120	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MEGPCKMM_01484	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MEGPCKMM_01485	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
MEGPCKMM_01486	0.0	-	-	-	M	ko:K13735	ko05100,map05100	ko00000,ko00001	domain protein
MEGPCKMM_01487	0.0	-	-	-	P	-	-	-	Voltage gated chloride channel
MEGPCKMM_01488	0.0	oxc	4.1.1.8	-	EH	ko:K01577	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
MEGPCKMM_01489	5.91e-222	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MEGPCKMM_01490	4.97e-276	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	hydrolase family 5
MEGPCKMM_01491	0.0	frc	2.8.3.15, 2.8.3.16	-	C	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MEGPCKMM_01492	2.89e-292	-	-	-	L	-	-	-	Phage integrase family
MEGPCKMM_01493	1.17e-280	-	-	-	H	-	-	-	Adenine-specific methyltransferase EcoRI
MEGPCKMM_01494	1.39e-284	-	-	-	L	-	-	-	HNH endonuclease
MEGPCKMM_01495	9.18e-49	-	-	-	-	-	-	-	-
MEGPCKMM_01496	8.16e-159	-	-	-	S	-	-	-	Plasmid replication protein
MEGPCKMM_01497	9.79e-182	-	-	-	D	ko:K03466	-	ko00000,ko03036	ftsk spoiiie
MEGPCKMM_01498	2.44e-86	-	-	-	-	-	-	-	-
MEGPCKMM_01499	5.62e-37	-	-	-	-	-	-	-	-
MEGPCKMM_01500	2.08e-270	-	-	-	-	-	-	-	-
MEGPCKMM_01502	6.66e-235	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MEGPCKMM_01503	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MEGPCKMM_01504	1.61e-261	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MEGPCKMM_01505	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MEGPCKMM_01506	2.54e-42	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEGPCKMM_01507	2.71e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEGPCKMM_01508	7.19e-196	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEGPCKMM_01509	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEGPCKMM_01510	1.72e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEGPCKMM_01511	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEGPCKMM_01512	1.28e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MEGPCKMM_01513	4.85e-180	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MEGPCKMM_01514	2.58e-223	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
MEGPCKMM_01515	9.9e-276	-	-	-	-	-	-	-	-
MEGPCKMM_01516	6.91e-235	-	-	-	-	-	-	-	-
MEGPCKMM_01517	1.96e-219	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
MEGPCKMM_01519	2.42e-235	-	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase 36 superfamily, catalytic domain
MEGPCKMM_01520	9.46e-144	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01521	1.23e-86	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
MEGPCKMM_01522	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
MEGPCKMM_01523	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MEGPCKMM_01524	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEGPCKMM_01525	1.26e-311	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MEGPCKMM_01526	4.17e-236	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEGPCKMM_01527	1.05e-299	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MEGPCKMM_01528	2.34e-266	amsE	-	-	M	-	-	-	Glycosyl transferase family 2
MEGPCKMM_01530	3.65e-253	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
MEGPCKMM_01531	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
MEGPCKMM_01532	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
MEGPCKMM_01533	0.0	glfT	2.4.1.288	GT2	S	ko:K16650	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MEGPCKMM_01534	2.57e-226	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MEGPCKMM_01535	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MEGPCKMM_01536	2.61e-239	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
MEGPCKMM_01537	1.62e-78	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
MEGPCKMM_01538	3.31e-130	-	-	-	M	-	-	-	hydrolase, family 25
MEGPCKMM_01539	1.2e-172	-	-	-	-	-	-	-	-
MEGPCKMM_01540	0.0	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
MEGPCKMM_01541	0.0	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEGPCKMM_01542	5.64e-194	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MEGPCKMM_01543	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MEGPCKMM_01545	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEGPCKMM_01546	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEGPCKMM_01547	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MEGPCKMM_01548	0.0	-	-	-	V	-	-	-	ABC transporter permease
MEGPCKMM_01549	4.6e-249	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MEGPCKMM_01550	8.09e-195	-	-	-	T	ko:K06950	-	ko00000	HD domain
MEGPCKMM_01551	1.17e-217	-	-	-	S	-	-	-	Glutamine amidotransferase domain
MEGPCKMM_01552	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MEGPCKMM_01553	1.7e-235	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
MEGPCKMM_01554	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MEGPCKMM_01555	6.89e-166	-	-	-	-	-	-	-	-
MEGPCKMM_01556	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MEGPCKMM_01557	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MEGPCKMM_01558	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEGPCKMM_01559	2.01e-167	-	-	-	-	-	-	-	-
MEGPCKMM_01560	9.93e-94	-	-	-	-	-	-	-	-
MEGPCKMM_01561	3.49e-221	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEGPCKMM_01562	0.0	pmt	2.4.1.109	GT39	O	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	ko00000,ko00001,ko01000,ko01003	C-terminal four TMM region of protein-O-mannosyltransferase
MEGPCKMM_01563	1.2e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MEGPCKMM_01564	2.12e-174	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MEGPCKMM_01566	6.19e-163	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MEGPCKMM_01567	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
MEGPCKMM_01568	4.71e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEGPCKMM_01569	1.2e-166	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
MEGPCKMM_01570	1.43e-119	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
MEGPCKMM_01571	4.87e-238	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
MEGPCKMM_01572	6.25e-132	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEGPCKMM_01573	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MEGPCKMM_01575	4.59e-247	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MEGPCKMM_01576	8.73e-187	traX	-	-	S	-	-	-	TraX protein
MEGPCKMM_01577	1.55e-190	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
MEGPCKMM_01578	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MEGPCKMM_01579	2.29e-226	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01580	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01581	5.8e-303	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEGPCKMM_01582	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
MEGPCKMM_01583	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MEGPCKMM_01584	3.35e-140	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MEGPCKMM_01585	1.7e-197	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MEGPCKMM_01586	1.1e-199	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEGPCKMM_01587	4.41e-232	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MEGPCKMM_01589	8.24e-308	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEGPCKMM_01590	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
MEGPCKMM_01591	1.4e-148	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MEGPCKMM_01592	4.02e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
MEGPCKMM_01593	1.44e-181	nfrA	-	-	C	-	-	-	Nitroreductase family
MEGPCKMM_01594	4.78e-59	-	-	-	-	-	-	-	-
MEGPCKMM_01595	3.96e-124	iolT	-	-	EGP	-	-	-	Major facilitator Superfamily
MEGPCKMM_01596	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MEGPCKMM_01597	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MEGPCKMM_01598	4.08e-216	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
MEGPCKMM_01599	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MEGPCKMM_01600	1.14e-166	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
MEGPCKMM_01601	0.0	araB	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
MEGPCKMM_01602	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
MEGPCKMM_01603	2.57e-250	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MEGPCKMM_01604	1.59e-71	-	-	-	-	-	-	-	-
MEGPCKMM_01605	3.58e-213	-	3.6.3.17	-	G	ko:K02056,ko:K10545	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEGPCKMM_01606	1.3e-48	-	-	-	-	-	-	-	-
MEGPCKMM_01607	7.3e-275	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MEGPCKMM_01608	3.01e-165	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MEGPCKMM_01609	4.68e-314	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MEGPCKMM_01610	1.87e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MEGPCKMM_01611	9.15e-158	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEGPCKMM_01612	7.41e-289	-	-	-	G	-	-	-	MFS/sugar transport protein
MEGPCKMM_01613	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
MEGPCKMM_01614	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain