ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LPNMMHEL_00001 6.35e-45 - - - M - - - Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LPNMMHEL_00002 1.02e-201 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LPNMMHEL_00003 1.85e-14 - - - - - - - -
LPNMMHEL_00005 1.32e-88 - - - S - - - Iron-sulphur cluster biosynthesis
LPNMMHEL_00006 3.05e-19 - 2.7.1.39 - S ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Phosphotransferase enzyme family
LPNMMHEL_00007 3.53e-145 - - - M - - - LysM domain
LPNMMHEL_00008 1.7e-57 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LPNMMHEL_00009 1.55e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LPNMMHEL_00010 3.98e-257 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LPNMMHEL_00011 1.27e-34 - - - S - - - MazG-like family
LPNMMHEL_00012 1.27e-113 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LPNMMHEL_00013 1.84e-56 - - - - - - - -
LPNMMHEL_00014 2.83e-92 - - - M - - - Glycosyl transferases group 1
LPNMMHEL_00016 1.3e-55 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
LPNMMHEL_00017 6.98e-216 yhgE - - V ko:K01421 - ko00000 domain protein
LPNMMHEL_00020 5.65e-257 - - - S - - - DUF218 domain
LPNMMHEL_00021 3.6e-127 - - - V - - - ABC transporter transmembrane region
LPNMMHEL_00022 1.86e-122 - - - S - - - Phospholipase A2
LPNMMHEL_00024 2.91e-39 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LPNMMHEL_00025 1.72e-22 - - - S - - - Bacteriophage abortive infection AbiH
LPNMMHEL_00026 2.55e-53 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LPNMMHEL_00027 6.18e-309 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LPNMMHEL_00029 2.42e-117 - - - T - - - ECF transporter, substrate-specific component
LPNMMHEL_00030 2.5e-231 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
LPNMMHEL_00031 3.86e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LPNMMHEL_00032 6.07e-192 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LPNMMHEL_00033 7.92e-76 yabA - - L - - - Involved in initiation control of chromosome replication
LPNMMHEL_00034 2.28e-223 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LPNMMHEL_00035 1.14e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
LPNMMHEL_00036 1.77e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LPNMMHEL_00037 2.95e-46 - - - S - - - Protein of unknown function (DUF2508)
LPNMMHEL_00038 1.26e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LPNMMHEL_00039 7e-49 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LPNMMHEL_00040 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPNMMHEL_00041 4.38e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LPNMMHEL_00042 9.05e-67 - - - - - - - -
LPNMMHEL_00043 1.12e-137 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LPNMMHEL_00044 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LPNMMHEL_00045 8.11e-60 - - - - - - - -
LPNMMHEL_00046 4.11e-223 ccpB - - K - - - lacI family
LPNMMHEL_00047 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LPNMMHEL_00048 6.63e-203 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LPNMMHEL_00049 1.05e-274 - - - M - - - Glycosyl hydrolases family 25
LPNMMHEL_00052 2.07e-86 - - - S - - - Pfam:Phage_holin_6_1
LPNMMHEL_00053 8.24e-55 - - - - - - - -
LPNMMHEL_00055 4.42e-41 - - - - - - - -
LPNMMHEL_00056 0.0 - - - S - - - peptidoglycan catabolic process
LPNMMHEL_00057 0.0 - - - S - - - Phage tail protein
LPNMMHEL_00058 0.0 - - - D - - - Phage tail tape measure protein
LPNMMHEL_00059 4.66e-87 - - - - - - - -
LPNMMHEL_00060 1.88e-69 - - - S - - - Phage tail assembly chaperone protein, TAC
LPNMMHEL_00061 4.16e-129 - - - S - - - Phage tail tube protein
LPNMMHEL_00062 6.75e-92 - - - S - - - Protein of unknown function (DUF3168)
LPNMMHEL_00063 1.48e-73 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LPNMMHEL_00064 1.63e-67 - - - - - - - -
LPNMMHEL_00065 3.6e-80 - - - S - - - Phage gp6-like head-tail connector protein
LPNMMHEL_00066 1.04e-191 - - - - - - - -
LPNMMHEL_00067 1.03e-237 - - - S - - - Phage major capsid protein E
LPNMMHEL_00068 9.65e-62 - - - - - - - -
LPNMMHEL_00069 2.48e-106 - - - S - - - Domain of unknown function (DUF4355)
LPNMMHEL_00071 2.04e-228 - - - S - - - head morphogenesis protein, SPP1 gp7 family
LPNMMHEL_00072 0.0 - - - S - - - Phage portal protein
LPNMMHEL_00073 1.55e-313 - - - S - - - Terminase-like family
LPNMMHEL_00074 1.31e-79 - - - L ko:K07474 - ko00000 Terminase small subunit
LPNMMHEL_00077 8.06e-280 - - - S - - - GcrA cell cycle regulator
LPNMMHEL_00078 4.87e-67 - - - - - - - -
LPNMMHEL_00081 1.34e-47 - - - - - - - -
LPNMMHEL_00085 1.84e-18 - - - - - - - -
LPNMMHEL_00086 7.91e-23 - - - - - - - -
LPNMMHEL_00087 3.95e-81 - - - S - - - Protein of unknown function (DUF1642)
LPNMMHEL_00090 7.94e-27 - - - - - - - -
LPNMMHEL_00091 1.33e-72 - - - S - - - Protein of unknown function (DUF1064)
LPNMMHEL_00092 1.15e-88 - - - - - - - -
LPNMMHEL_00093 1.01e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
LPNMMHEL_00094 2e-107 - - - S - - - HNH endonuclease
LPNMMHEL_00095 2.82e-90 - - - S - - - Single-strand binding protein family
LPNMMHEL_00096 2.76e-108 - - - L - - - Replication initiation and membrane attachment
LPNMMHEL_00097 2.75e-15 - - - L ko:K07451 - ko00000,ko01000,ko02048 PFAM HNH endonuclease
LPNMMHEL_00098 1.48e-172 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
LPNMMHEL_00099 3.26e-180 - - - L ko:K07455 - ko00000,ko03400 RecT family
LPNMMHEL_00102 7e-21 - - - - - - - -
LPNMMHEL_00106 3.67e-07 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LPNMMHEL_00107 6.25e-37 - 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Peptidase S24-like
LPNMMHEL_00109 6.44e-72 - - - S - - - Domain of unknown function (DUF4352)
LPNMMHEL_00113 1.39e-92 - - - S - - - Pyridoxamine 5'-phosphate oxidase
LPNMMHEL_00114 1.5e-37 soj1 - - D ko:K03496 - ko00000,ko03036,ko04812 Anion-transporting ATPase
LPNMMHEL_00117 2.24e-126 - - - L - - - Belongs to the 'phage' integrase family
LPNMMHEL_00118 2.27e-73 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LPNMMHEL_00119 4.18e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LPNMMHEL_00121 1.92e-283 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LPNMMHEL_00122 1.41e-185 - - - K - - - acetyltransferase
LPNMMHEL_00123 4.87e-86 - - - - - - - -
LPNMMHEL_00124 8.37e-278 yceI - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
LPNMMHEL_00125 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LPNMMHEL_00126 5.42e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LPNMMHEL_00127 6.87e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LPNMMHEL_00128 8.99e-122 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
LPNMMHEL_00129 3.42e-84 - - - S - - - Leucine-rich repeat (LRR) protein
LPNMMHEL_00130 2.02e-137 - - - N - - - WxL domain surface cell wall-binding
LPNMMHEL_00131 2.68e-75 - - - - - - - -
LPNMMHEL_00132 1.17e-72 - - - S - - - WxL domain surface cell wall-binding
LPNMMHEL_00133 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LPNMMHEL_00134 5.55e-70 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LPNMMHEL_00135 4.09e-131 yobS - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_00136 1.16e-48 - 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
LPNMMHEL_00137 2.93e-209 - 4.2.1.46 - GM ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Male sterility protein
LPNMMHEL_00138 1.4e-243 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
LPNMMHEL_00139 5.71e-97 - - - S - - - Short repeat of unknown function (DUF308)
LPNMMHEL_00140 1.2e-158 - - - S - - - AAA-like domain
LPNMMHEL_00141 3.05e-304 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPNMMHEL_00142 1.45e-46 - - - - - - - -
LPNMMHEL_00143 8.28e-48 - - - S - - - Protein of unknown function (DUF1722)
LPNMMHEL_00144 6.92e-242 ysdE - - P - - - Citrate transporter
LPNMMHEL_00145 5.99e-77 - - - S - - - Protein of unknown function (DUF1722)
LPNMMHEL_00146 3.35e-84 - - - S - - - Protein of unknown function (DUF1093)
LPNMMHEL_00147 7.29e-18 yjbB - - G - - - Permeases of the major facilitator superfamily
LPNMMHEL_00148 6.99e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
LPNMMHEL_00149 5.32e-213 - - - S - - - Conjugative transposon protein TcpC
LPNMMHEL_00150 4.5e-129 - - - - - - - -
LPNMMHEL_00151 4.37e-240 yddH - - M - - - NlpC/P60 family
LPNMMHEL_00152 0.0 - - - M - - - Psort location CytoplasmicMembrane, score
LPNMMHEL_00153 0.0 - - - S - - - AAA-like domain
LPNMMHEL_00154 1.4e-90 - - - S - - - TcpE family
LPNMMHEL_00155 9.62e-116 - - - S - - - Antirestriction protein (ArdA)
LPNMMHEL_00156 1.84e-41 - - - S - - - Psort location CytoplasmicMembrane, score
LPNMMHEL_00157 1.04e-54 yhdJ 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-4 methylation of cytosine
LPNMMHEL_00158 4.06e-64 - - - L - - - DNA methylase
LPNMMHEL_00159 6.4e-72 - - - - - - - -
LPNMMHEL_00160 1.2e-293 - - - K ko:K07467 - ko00000 Replication initiation factor
LPNMMHEL_00164 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
LPNMMHEL_00169 9.96e-82 - - - S - - - Bacterial protein of unknown function (DUF961)
LPNMMHEL_00170 4.02e-69 - - - S - - - Bacterial protein of unknown function (DUF961)
LPNMMHEL_00171 3.36e-42 - - - - - - - -
LPNMMHEL_00172 0.0 - - - M - - - domain protein
LPNMMHEL_00173 0.0 - - - M - - - domain protein
LPNMMHEL_00174 2.29e-87 - - - - - - - -
LPNMMHEL_00175 4.33e-162 - - - - - - - -
LPNMMHEL_00176 4.35e-159 - - - S - - - Tetratricopeptide repeat
LPNMMHEL_00177 1.7e-187 - - - - - - - -
LPNMMHEL_00178 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LPNMMHEL_00180 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LPNMMHEL_00181 2.63e-82 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LPNMMHEL_00182 4.64e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LPNMMHEL_00183 4.66e-44 - - - - - - - -
LPNMMHEL_00184 5.68e-83 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LPNMMHEL_00185 1.63e-111 queT - - S - - - QueT transporter
LPNMMHEL_00186 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
LPNMMHEL_00187 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
LPNMMHEL_00189 2.31e-166 yciB - - M - - - ErfK YbiS YcfS YnhG
LPNMMHEL_00190 1.34e-154 - - - S - - - (CBS) domain
LPNMMHEL_00191 0.0 - - - S - - - Putative peptidoglycan binding domain
LPNMMHEL_00192 2.05e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LPNMMHEL_00193 1.74e-130 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LPNMMHEL_00194 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LPNMMHEL_00195 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LPNMMHEL_00196 1.99e-53 yabO - - J - - - S4 domain protein
LPNMMHEL_00197 1.19e-85 divIC - - D ko:K05589,ko:K13052 - ko00000,ko03036 cell cycle
LPNMMHEL_00198 1.17e-105 yabR - - J ko:K07571 - ko00000 RNA binding
LPNMMHEL_00199 6.04e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LPNMMHEL_00200 1.14e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LPNMMHEL_00201 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LPNMMHEL_00202 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
LPNMMHEL_00203 1.95e-249 - - - S - - - Protein of unknown function C-terminal (DUF3324)
LPNMMHEL_00204 1.67e-243 - - - S - - - Bacterial protein of unknown function (DUF916)
LPNMMHEL_00205 1.52e-208 - - - S - - - WxL domain surface cell wall-binding
LPNMMHEL_00206 2.08e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LPNMMHEL_00207 3.08e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LPNMMHEL_00208 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LPNMMHEL_00209 1.3e-190 - - - S - - - Putative transposase
LPNMMHEL_00210 7.73e-74 - - - L - - - Integrase
LPNMMHEL_00211 7.68e-84 - - - - - - - -
LPNMMHEL_00212 2.06e-38 - - - - - - - -
LPNMMHEL_00213 0.0 - - - L - - - Transposase DDE domain
LPNMMHEL_00214 3.9e-83 - - - - - - - -
LPNMMHEL_00215 4.19e-55 isp - - L - - - Transposase
LPNMMHEL_00216 2.61e-44 - - - - - - - -
LPNMMHEL_00217 2.33e-302 - - - L ko:K07485 - ko00000 Transposase
LPNMMHEL_00218 1.24e-58 - - - L - - - Transposase and inactivated derivatives, IS30 family
LPNMMHEL_00219 1.41e-163 - - - P - - - integral membrane protein, YkoY family
LPNMMHEL_00220 8.71e-59 - - - L ko:K07483 - ko00000 4.5 Transposon and IS
LPNMMHEL_00221 7.23e-200 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
LPNMMHEL_00222 1.36e-242 - - - L - - - Transposase and inactivated derivatives, IS30 family
LPNMMHEL_00223 2.45e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
LPNMMHEL_00224 3.64e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LPNMMHEL_00225 2.43e-243 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LPNMMHEL_00226 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_00227 2.95e-110 - - - - - - - -
LPNMMHEL_00228 1.25e-282 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LPNMMHEL_00229 8.71e-200 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPNMMHEL_00230 4.36e-302 XK27_05225 - - S - - - Tetratricopeptide repeat protein
LPNMMHEL_00231 1.2e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LPNMMHEL_00232 8.65e-311 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LPNMMHEL_00233 1.72e-303 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LPNMMHEL_00234 2.04e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LPNMMHEL_00235 1.68e-104 - - - M - - - Lysin motif
LPNMMHEL_00236 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LPNMMHEL_00237 3.7e-234 - - - S - - - Helix-turn-helix domain
LPNMMHEL_00238 1.92e-59 fer - - C ko:K05337 - ko00000 4Fe-4S single cluster domain of Ferredoxin I
LPNMMHEL_00239 4.35e-123 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LPNMMHEL_00240 3.15e-175 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LPNMMHEL_00241 8.74e-139 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LPNMMHEL_00242 1.07e-159 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LPNMMHEL_00243 1.59e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LPNMMHEL_00244 9.95e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
LPNMMHEL_00245 3.45e-206 yitL - - S ko:K00243 - ko00000 S1 domain
LPNMMHEL_00246 4.31e-95 ytwI - - S - - - Protein of unknown function (DUF441)
LPNMMHEL_00247 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LPNMMHEL_00248 6.33e-227 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LPNMMHEL_00249 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LPNMMHEL_00250 8.1e-36 - - - S - - - Protein of unknown function (DUF2929)
LPNMMHEL_00251 4.99e-184 - - - - - - - -
LPNMMHEL_00252 0.0 ycjM 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
LPNMMHEL_00253 6.3e-123 - - - K - - - Domain of unknown function (DUF1836)
LPNMMHEL_00254 1.35e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LPNMMHEL_00255 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LPNMMHEL_00256 4.1e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
LPNMMHEL_00257 1.83e-183 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
LPNMMHEL_00258 1.1e-232 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LPNMMHEL_00259 0.0 oatA - - I - - - Acyltransferase
LPNMMHEL_00260 3.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LPNMMHEL_00261 2.78e-170 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
LPNMMHEL_00262 2.76e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LPNMMHEL_00263 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
LPNMMHEL_00264 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LPNMMHEL_00265 1.89e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_00266 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LPNMMHEL_00267 3.33e-28 - - - - - - - -
LPNMMHEL_00268 2.28e-63 - - - S - - - mazG nucleotide pyrophosphohydrolase
LPNMMHEL_00269 2.74e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LPNMMHEL_00270 1.19e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LPNMMHEL_00271 9.55e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LPNMMHEL_00272 0.0 yknV - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LPNMMHEL_00273 4.73e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LPNMMHEL_00274 1.93e-213 - - - S - - - Tetratricopeptide repeat
LPNMMHEL_00275 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LPNMMHEL_00276 5.41e-62 - - - - - - - -
LPNMMHEL_00277 8.73e-96 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
LPNMMHEL_00278 4.54e-264 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LPNMMHEL_00279 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LPNMMHEL_00280 1.83e-87 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LPNMMHEL_00281 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LPNMMHEL_00282 2.06e-150 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
LPNMMHEL_00283 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LPNMMHEL_00284 7.25e-264 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPNMMHEL_00285 1.13e-307 ytoI - - K - - - DRTGG domain
LPNMMHEL_00286 3.03e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LPNMMHEL_00287 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LPNMMHEL_00288 1.55e-223 - - - - - - - -
LPNMMHEL_00289 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LPNMMHEL_00291 4.89e-58 yrzL - - S - - - Belongs to the UPF0297 family
LPNMMHEL_00292 2.67e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LPNMMHEL_00293 1.3e-69 yrzB - - S - - - Belongs to the UPF0473 family
LPNMMHEL_00294 2.84e-48 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LPNMMHEL_00295 1.89e-119 cvpA - - S - - - Colicin V production protein
LPNMMHEL_00296 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LPNMMHEL_00297 3.64e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LPNMMHEL_00298 1.04e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
LPNMMHEL_00299 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNMMHEL_00300 1.99e-303 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
LPNMMHEL_00301 6.97e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNMMHEL_00302 8.29e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LPNMMHEL_00303 6.77e-111 yslB - - S - - - Protein of unknown function (DUF2507)
LPNMMHEL_00304 0.0 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LPNMMHEL_00305 1.64e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LPNMMHEL_00306 1.9e-175 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
LPNMMHEL_00307 9.32e-112 ykuL - - S - - - CBS domain
LPNMMHEL_00308 1.62e-199 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
LPNMMHEL_00309 6.86e-198 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
LPNMMHEL_00310 2.12e-46 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LPNMMHEL_00311 1.39e-113 ytxH - - S - - - YtxH-like protein
LPNMMHEL_00312 7.49e-117 yrxA - - S ko:K07105 - ko00000 3H domain
LPNMMHEL_00313 2.2e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LPNMMHEL_00314 3.03e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LPNMMHEL_00315 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
LPNMMHEL_00316 1.06e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
LPNMMHEL_00317 5.87e-177 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LPNMMHEL_00318 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
LPNMMHEL_00319 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
LPNMMHEL_00320 9.98e-73 - - - - - - - -
LPNMMHEL_00321 1.46e-241 yibE - - S - - - overlaps another CDS with the same product name
LPNMMHEL_00322 3.27e-151 yibF - - S - - - overlaps another CDS with the same product name
LPNMMHEL_00323 7.41e-148 - - - S - - - Calcineurin-like phosphoesterase
LPNMMHEL_00324 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LPNMMHEL_00325 1.19e-149 yutD - - S - - - Protein of unknown function (DUF1027)
LPNMMHEL_00326 1.34e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LPNMMHEL_00327 6.43e-146 - - - S - - - Protein of unknown function (DUF1461)
LPNMMHEL_00328 8.69e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
LPNMMHEL_00329 2.26e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
LPNMMHEL_00330 1.35e-237 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LPNMMHEL_00331 2.99e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LPNMMHEL_00332 1.17e-82 yugI - - J ko:K07570 - ko00000 general stress protein
LPNMMHEL_00333 0.0 choS - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LPNMMHEL_00334 6.07e-225 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_00335 9.36e-317 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LPNMMHEL_00336 7.28e-25 - - - V - - - ATPases associated with a variety of cellular activities
LPNMMHEL_00337 2.22e-170 - - - V - - - ATPases associated with a variety of cellular activities
LPNMMHEL_00338 7.8e-189 - - - V - - - efflux transmembrane transporter activity
LPNMMHEL_00339 2.86e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LPNMMHEL_00340 1.15e-132 lemA - - S ko:K03744 - ko00000 LemA family
LPNMMHEL_00341 7.19e-157 - - - S ko:K06872 - ko00000 TPM domain
LPNMMHEL_00342 5.58e-306 dinF - - V - - - MatE
LPNMMHEL_00343 2.76e-120 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
LPNMMHEL_00344 6.93e-197 - - - Q - - - Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
LPNMMHEL_00345 1.74e-224 ydhF - - S - - - Aldo keto reductase
LPNMMHEL_00346 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LPNMMHEL_00347 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LPNMMHEL_00348 2.57e-223 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LPNMMHEL_00349 5.77e-204 ypuA - - S - - - Protein of unknown function (DUF1002)
LPNMMHEL_00350 4.7e-50 - - - - - - - -
LPNMMHEL_00351 3.21e-125 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
LPNMMHEL_00352 3.77e-218 - - - - - - - -
LPNMMHEL_00353 6.41e-24 - - - - - - - -
LPNMMHEL_00354 8.06e-165 cobB - - K ko:K12410 - ko00000,ko01000 Sir2 family
LPNMMHEL_00355 9.14e-139 yiiE - - S - - - Protein of unknown function (DUF1211)
LPNMMHEL_00356 3.11e-218 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LPNMMHEL_00357 2.58e-117 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
LPNMMHEL_00358 9.84e-195 yunF - - F - - - Protein of unknown function DUF72
LPNMMHEL_00359 4.11e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LPNMMHEL_00360 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPNMMHEL_00361 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
LPNMMHEL_00362 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
LPNMMHEL_00363 1.18e-198 - - - T - - - GHKL domain
LPNMMHEL_00364 1.67e-159 - - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LPNMMHEL_00365 4.09e-219 yqhA - - G - - - Aldose 1-epimerase
LPNMMHEL_00366 1.35e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
LPNMMHEL_00367 3e-103 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
LPNMMHEL_00368 1.24e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
LPNMMHEL_00369 7.92e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LPNMMHEL_00370 2.04e-202 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LPNMMHEL_00371 4.13e-51 veg - - S - - - Biofilm formation stimulator VEG
LPNMMHEL_00372 6.63e-232 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LPNMMHEL_00373 1.99e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
LPNMMHEL_00374 1.38e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
LPNMMHEL_00375 1.84e-154 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_00376 1.01e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LPNMMHEL_00377 7.27e-286 ysaA - - V - - - RDD family
LPNMMHEL_00378 3.84e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LPNMMHEL_00379 2.2e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPNMMHEL_00380 1.54e-73 nudA - - S - - - ASCH
LPNMMHEL_00381 2.67e-244 - - - E - - - glutamate:sodium symporter activity
LPNMMHEL_00382 1.09e-243 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
LPNMMHEL_00383 8.89e-218 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LPNMMHEL_00384 5.32e-145 - - - Q - - - Methyltransferase
LPNMMHEL_00385 2.16e-68 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
LPNMMHEL_00386 1.5e-171 - - - S - - - -acetyltransferase
LPNMMHEL_00387 3.92e-120 yfbM - - K - - - FR47-like protein
LPNMMHEL_00388 2.42e-122 - - - E - - - HAD-hyrolase-like
LPNMMHEL_00389 1.3e-239 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
LPNMMHEL_00390 1.33e-178 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LPNMMHEL_00391 3.86e-119 - - - K - - - Acetyltransferase (GNAT) domain
LPNMMHEL_00392 7.83e-108 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LPNMMHEL_00393 1.34e-98 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LPNMMHEL_00394 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LPNMMHEL_00395 2.57e-252 ysdE - - P - - - Citrate transporter
LPNMMHEL_00396 1.23e-90 - - - - - - - -
LPNMMHEL_00397 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
LPNMMHEL_00398 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LPNMMHEL_00399 1.43e-133 - - - - - - - -
LPNMMHEL_00400 0.0 cadA - - P - - - P-type ATPase
LPNMMHEL_00401 1.8e-99 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LPNMMHEL_00402 2.35e-92 - - - S - - - Iron-sulphur cluster biosynthesis
LPNMMHEL_00403 1.14e-282 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
LPNMMHEL_00404 1.24e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
LPNMMHEL_00405 1.05e-182 yycI - - S - - - YycH protein
LPNMMHEL_00406 0.0 yycH - - S - - - YycH protein
LPNMMHEL_00407 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNMMHEL_00408 3.03e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LPNMMHEL_00409 5.03e-156 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha/beta hydrolase family
LPNMMHEL_00410 0.0 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LPNMMHEL_00411 1.63e-298 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LPNMMHEL_00412 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LPNMMHEL_00413 5.58e-272 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LPNMMHEL_00414 9.09e-97 - - - S - - - Domain of unknown function (DUF3284)
LPNMMHEL_00415 1.76e-298 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_00416 1.97e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
LPNMMHEL_00417 3.39e-67 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_00418 8.36e-72 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
LPNMMHEL_00419 3.03e-139 yokL3 - - J - - - Acetyltransferase (GNAT) domain
LPNMMHEL_00420 1.84e-110 - - - F - - - NUDIX domain
LPNMMHEL_00421 3.71e-117 - - - S - - - AAA domain
LPNMMHEL_00422 3.32e-148 ycaC - - Q - - - Isochorismatase family
LPNMMHEL_00423 3.63e-106 - - - EGP - - - Major Facilitator Superfamily
LPNMMHEL_00424 3.07e-208 - - - EGP - - - Major Facilitator Superfamily
LPNMMHEL_00425 5.62e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
LPNMMHEL_00426 4.25e-220 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LPNMMHEL_00427 1.08e-84 manO - - S - - - Domain of unknown function (DUF956)
LPNMMHEL_00428 1.73e-216 manN - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LPNMMHEL_00429 1.57e-171 manM - - G ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
LPNMMHEL_00430 8.35e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LPNMMHEL_00431 1.97e-278 - - - EGP - - - Major facilitator Superfamily
LPNMMHEL_00432 5.38e-06 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_00433 0.0 poxL 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LPNMMHEL_00434 5.25e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
LPNMMHEL_00435 4.66e-267 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
LPNMMHEL_00436 1.41e-265 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LPNMMHEL_00437 7.23e-66 - - - - - - - -
LPNMMHEL_00438 2.34e-205 - - - G - - - Xylose isomerase domain protein TIM barrel
LPNMMHEL_00439 4.44e-134 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
LPNMMHEL_00440 9.15e-201 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 converts alpha-aldose to the beta-anomer
LPNMMHEL_00441 3.11e-271 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LPNMMHEL_00442 4.33e-132 - - - S - - - ECF transporter, substrate-specific component
LPNMMHEL_00444 5.69e-105 - - - K - - - Acetyltransferase GNAT Family
LPNMMHEL_00445 6.72e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LPNMMHEL_00446 2.36e-167 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_00447 2.83e-188 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LPNMMHEL_00448 1.43e-197 XK27_08835 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_00450 5.58e-94 - - - - - - - -
LPNMMHEL_00451 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LPNMMHEL_00452 1.97e-277 - - - V - - - Beta-lactamase
LPNMMHEL_00453 1.45e-194 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LPNMMHEL_00454 2.6e-279 - - - V - - - Beta-lactamase
LPNMMHEL_00455 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LPNMMHEL_00456 1.62e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LPNMMHEL_00457 7.45e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LPNMMHEL_00458 7.6e-176 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LPNMMHEL_00459 0.0 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
LPNMMHEL_00462 8.48e-203 - - - S - - - Calcineurin-like phosphoesterase
LPNMMHEL_00463 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
LPNMMHEL_00464 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_00465 6.98e-87 - - - - - - - -
LPNMMHEL_00466 6.13e-100 - - - S - - - function, without similarity to other proteins
LPNMMHEL_00467 9.06e-182 - - - G - - - MFS/sugar transport protein
LPNMMHEL_00468 1.49e-138 - - - G - - - MFS/sugar transport protein
LPNMMHEL_00469 2.17e-291 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
LPNMMHEL_00470 3.32e-76 - - - - - - - -
LPNMMHEL_00471 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
LPNMMHEL_00472 6.28e-25 - - - S - - - Virus attachment protein p12 family
LPNMMHEL_00473 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
LPNMMHEL_00474 2.48e-55 feoA - - P ko:K04758 - ko00000,ko02000 FeoA
LPNMMHEL_00475 1.24e-31 - - - P ko:K04758 - ko00000,ko02000 FeoA
LPNMMHEL_00476 8.24e-168 - - - E - - - lipolytic protein G-D-S-L family
LPNMMHEL_00479 4.34e-151 - - - S ko:K07118 - ko00000 NAD(P)H-binding
LPNMMHEL_00480 8.14e-79 - - - S - - - MucBP domain
LPNMMHEL_00481 9.73e-109 - - - - - - - -
LPNMMHEL_00482 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
LPNMMHEL_00484 1.78e-266 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LPNMMHEL_00485 7.09e-180 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
LPNMMHEL_00486 1.62e-45 - - - S - - - Bacterial protein of unknown function (DUF898)
LPNMMHEL_00488 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LPNMMHEL_00489 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LPNMMHEL_00490 4.26e-271 camS - - S - - - sex pheromone
LPNMMHEL_00491 3.61e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPNMMHEL_00492 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LPNMMHEL_00493 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPNMMHEL_00494 4.97e-248 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
LPNMMHEL_00495 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPNMMHEL_00496 2.63e-111 yttB - - EGP - - - Major Facilitator
LPNMMHEL_00497 9.27e-151 yttB - - EGP - - - Major Facilitator
LPNMMHEL_00498 1.2e-188 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LPNMMHEL_00499 1.41e-209 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
LPNMMHEL_00500 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LPNMMHEL_00501 0.0 - - - EGP - - - Major Facilitator
LPNMMHEL_00502 4.04e-103 - - - K - - - Acetyltransferase (GNAT) family
LPNMMHEL_00503 2.87e-213 yitS - - S - - - Uncharacterised protein, DegV family COG1307
LPNMMHEL_00504 3.38e-166 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LPNMMHEL_00505 1.24e-39 - - - - - - - -
LPNMMHEL_00506 8.06e-177 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LPNMMHEL_00507 3.83e-79 - - - S - - - Protein of unknown function (DUF1093)
LPNMMHEL_00508 1.9e-79 - - - S - - - Domain of unknown function (DUF4828)
LPNMMHEL_00509 1.81e-225 mocA - - S - - - Oxidoreductase
LPNMMHEL_00510 4.41e-289 yfmL - - L - - - DEAD DEAH box helicase
LPNMMHEL_00511 2.76e-74 chbA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
LPNMMHEL_00512 6.37e-93 - - - S - - - Domain of unknown function (DUF3284)
LPNMMHEL_00514 3.06e-07 - - - - - - - -
LPNMMHEL_00515 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LPNMMHEL_00516 4.53e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
LPNMMHEL_00517 2.96e-144 - - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_00519 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
LPNMMHEL_00520 9.73e-230 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LPNMMHEL_00521 1.24e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
LPNMMHEL_00522 1.16e-204 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LPNMMHEL_00523 7.16e-257 - - - M - - - Glycosyltransferase like family 2
LPNMMHEL_00525 1.02e-20 - - - - - - - -
LPNMMHEL_00526 1.09e-253 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
LPNMMHEL_00527 1.31e-216 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LPNMMHEL_00529 1.32e-202 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
LPNMMHEL_00530 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LPNMMHEL_00531 2.98e-216 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LPNMMHEL_00532 1.27e-186 gntR - - K - - - rpiR family
LPNMMHEL_00533 8.2e-211 yvgN - - C - - - Aldo keto reductase
LPNMMHEL_00534 1.1e-181 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LPNMMHEL_00535 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LPNMMHEL_00536 2.06e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LPNMMHEL_00537 9.18e-302 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LPNMMHEL_00538 2.81e-278 hpk31 - - T - - - Histidine kinase
LPNMMHEL_00539 1.68e-156 vanR - - K - - - response regulator
LPNMMHEL_00540 1.18e-155 - - - - - - - -
LPNMMHEL_00541 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LPNMMHEL_00542 7.12e-169 - - - S - - - Protein of unknown function (DUF1129)
LPNMMHEL_00543 2.8e-236 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LPNMMHEL_00544 3.26e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
LPNMMHEL_00545 1.11e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LPNMMHEL_00546 1.49e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
LPNMMHEL_00547 1.88e-186 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LPNMMHEL_00548 2.27e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
LPNMMHEL_00549 2.32e-86 - - - - - - - -
LPNMMHEL_00550 1.35e-164 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
LPNMMHEL_00551 6.15e-139 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
LPNMMHEL_00552 5.7e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LPNMMHEL_00553 1.42e-195 - - - S - - - Protein of unknown function (DUF979)
LPNMMHEL_00554 1.08e-146 - - - S - - - Protein of unknown function (DUF969)
LPNMMHEL_00556 1.97e-92 asp2 - - S - - - Asp23 family, cell envelope-related function
LPNMMHEL_00557 8.12e-90 asp23 - - S - - - Asp23 family, cell envelope-related function
LPNMMHEL_00558 4.15e-34 - - - - - - - -
LPNMMHEL_00559 1.16e-112 - - - S - - - Protein conserved in bacteria
LPNMMHEL_00560 1.93e-52 - - - S - - - Transglycosylase associated protein
LPNMMHEL_00561 2.27e-94 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
LPNMMHEL_00562 2.86e-219 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPNMMHEL_00563 2.82e-36 - - - - - - - -
LPNMMHEL_00564 5.54e-50 - - - - - - - -
LPNMMHEL_00565 1.63e-109 - - - C - - - Flavodoxin
LPNMMHEL_00566 4.85e-65 - - - - - - - -
LPNMMHEL_00567 5.12e-117 - - - - - - - -
LPNMMHEL_00568 1.47e-07 - - - - - - - -
LPNMMHEL_00569 6.45e-74 ywjH - - S - - - Protein of unknown function (DUF1634)
LPNMMHEL_00570 8.76e-178 yunE - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
LPNMMHEL_00571 1.71e-286 - - - S ko:K06872 - ko00000 TPM domain
LPNMMHEL_00572 4.18e-148 - - - - - - - -
LPNMMHEL_00573 1.32e-135 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LPNMMHEL_00574 1.36e-174 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LPNMMHEL_00575 0.0 fnq20 - - S - - - FAD-NAD(P)-binding
LPNMMHEL_00576 3.59e-141 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
LPNMMHEL_00577 9.64e-285 - - - V - - - ABC transporter transmembrane region
LPNMMHEL_00578 8.98e-275 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
LPNMMHEL_00579 1.39e-101 - - - S - - - NUDIX domain
LPNMMHEL_00580 1.91e-56 - - - - - - - -
LPNMMHEL_00581 4.83e-49 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_00582 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LPNMMHEL_00583 6.84e-183 - - - - - - - -
LPNMMHEL_00584 9.96e-271 - - - S - - - Membrane
LPNMMHEL_00585 4.58e-82 - - - S - - - Protein of unknown function (DUF1093)
LPNMMHEL_00586 6.43e-66 - - - - - - - -
LPNMMHEL_00587 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LPNMMHEL_00588 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LPNMMHEL_00589 4.14e-232 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
LPNMMHEL_00590 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
LPNMMHEL_00592 2.86e-304 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
LPNMMHEL_00593 2.96e-242 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LPNMMHEL_00594 6.98e-53 - - - - - - - -
LPNMMHEL_00595 1.22e-112 - - - - - - - -
LPNMMHEL_00596 6.71e-34 - - - - - - - -
LPNMMHEL_00597 4.72e-211 - - - EG - - - EamA-like transporter family
LPNMMHEL_00598 4.03e-143 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LPNMMHEL_00599 9.59e-101 usp5 - - T - - - universal stress protein
LPNMMHEL_00600 3.25e-74 - - - K - - - Helix-turn-helix domain
LPNMMHEL_00601 9.49e-186 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LPNMMHEL_00602 6.69e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
LPNMMHEL_00603 1.54e-84 - - - - - - - -
LPNMMHEL_00604 2.03e-112 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LPNMMHEL_00605 9.59e-92 adhR - - K - - - helix_turn_helix, mercury resistance
LPNMMHEL_00606 2.59e-107 - - - C - - - Flavodoxin
LPNMMHEL_00607 2.46e-249 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LPNMMHEL_00608 7.57e-146 - - - GM - - - NmrA-like family
LPNMMHEL_00610 2.29e-131 - - - Q - - - methyltransferase
LPNMMHEL_00611 3.31e-137 - - - T - - - Sh3 type 3 domain protein
LPNMMHEL_00612 7.85e-151 - - - F - - - glutamine amidotransferase
LPNMMHEL_00613 5.22e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
LPNMMHEL_00614 0.0 yhdP - - S - - - Transporter associated domain
LPNMMHEL_00615 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
LPNMMHEL_00616 4.84e-79 - - - S - - - Domain of unknown function (DUF4811)
LPNMMHEL_00617 7.96e-127 maf - - D ko:K06287 - ko00000 nucleoside-triphosphate diphosphatase activity
LPNMMHEL_00618 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LPNMMHEL_00619 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LPNMMHEL_00620 0.0 ydaO - - E - - - amino acid
LPNMMHEL_00621 6.55e-75 - - - S - - - Domain of unknown function (DUF1827)
LPNMMHEL_00622 1.27e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LPNMMHEL_00623 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LPNMMHEL_00624 1.29e-60 ylxQ - - J - - - ribosomal protein
LPNMMHEL_00625 9.63e-61 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
LPNMMHEL_00626 4.13e-277 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LPNMMHEL_00627 1.33e-110 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LPNMMHEL_00628 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPNMMHEL_00629 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LPNMMHEL_00630 3.52e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LPNMMHEL_00631 7.66e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LPNMMHEL_00632 8.7e-179 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LPNMMHEL_00633 1.73e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LPNMMHEL_00634 5.86e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LPNMMHEL_00635 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LPNMMHEL_00636 1.18e-182 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LPNMMHEL_00637 1.88e-61 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
LPNMMHEL_00638 1.18e-167 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LPNMMHEL_00639 8.45e-160 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
LPNMMHEL_00640 1.36e-292 yhdG - - E ko:K03294 - ko00000 Amino Acid
LPNMMHEL_00641 4.28e-181 yejC - - S - - - Protein of unknown function (DUF1003)
LPNMMHEL_00642 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_00643 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_00644 1.39e-40 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LPNMMHEL_00645 2.84e-48 ynzC - - S - - - UPF0291 protein
LPNMMHEL_00646 9.42e-28 - - - - - - - -
LPNMMHEL_00647 2e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LPNMMHEL_00648 6.15e-186 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LPNMMHEL_00649 2.16e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LPNMMHEL_00650 1.55e-51 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LPNMMHEL_00651 2.97e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LPNMMHEL_00652 2.16e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LPNMMHEL_00653 1.26e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LPNMMHEL_00655 7.91e-70 - - - - - - - -
LPNMMHEL_00656 2.6e-232 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LPNMMHEL_00657 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LPNMMHEL_00658 2.8e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LPNMMHEL_00659 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LPNMMHEL_00660 1.8e-197 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNMMHEL_00661 3.2e-216 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LPNMMHEL_00662 5.65e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNMMHEL_00663 4.24e-247 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNMMHEL_00664 3.21e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPNMMHEL_00665 1.41e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LPNMMHEL_00666 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LPNMMHEL_00667 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
LPNMMHEL_00668 5.83e-75 yloU - - S - - - Asp23 family, cell envelope-related function
LPNMMHEL_00669 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LPNMMHEL_00670 5.28e-166 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LPNMMHEL_00671 4.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LPNMMHEL_00672 4.61e-220 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LPNMMHEL_00673 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LPNMMHEL_00674 5.22e-174 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LPNMMHEL_00675 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LPNMMHEL_00676 9.71e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LPNMMHEL_00677 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LPNMMHEL_00678 2.29e-274 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LPNMMHEL_00679 1.77e-47 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LPNMMHEL_00680 4.02e-92 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LPNMMHEL_00681 2.27e-44 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LPNMMHEL_00682 9.51e-117 - - - S ko:K07001 - ko00000 Patatin-like phospholipase
LPNMMHEL_00683 1.57e-65 - - - - - - - -
LPNMMHEL_00685 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LPNMMHEL_00686 4.19e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LPNMMHEL_00687 3.3e-196 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
LPNMMHEL_00688 3.67e-189 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LPNMMHEL_00689 1.42e-43 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LPNMMHEL_00690 3.14e-295 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LPNMMHEL_00691 1.05e-191 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LPNMMHEL_00692 6.72e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LPNMMHEL_00693 9.44e-99 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
LPNMMHEL_00694 6.06e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LPNMMHEL_00695 2.92e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LPNMMHEL_00696 1.6e-63 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LPNMMHEL_00697 1.77e-74 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
LPNMMHEL_00698 5.83e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LPNMMHEL_00699 1.17e-16 - - - - - - - -
LPNMMHEL_00702 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LPNMMHEL_00703 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LPNMMHEL_00704 1.32e-80 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
LPNMMHEL_00705 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
LPNMMHEL_00706 5.52e-303 ynbB - - P - - - aluminum resistance
LPNMMHEL_00707 6.3e-222 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LPNMMHEL_00708 3.33e-35 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
LPNMMHEL_00709 1.93e-96 yqhL - - P - - - Rhodanese-like protein
LPNMMHEL_00710 1.13e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LPNMMHEL_00711 3.93e-54 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
LPNMMHEL_00712 1.33e-157 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
LPNMMHEL_00713 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LPNMMHEL_00714 0.0 - - - S - - - Bacterial membrane protein YfhO
LPNMMHEL_00715 1.15e-71 yneR - - S - - - Belongs to the HesB IscA family
LPNMMHEL_00716 2.04e-149 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
LPNMMHEL_00717 3.81e-231 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNMMHEL_00718 1.1e-164 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
LPNMMHEL_00719 1.05e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LPNMMHEL_00720 3.43e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LPNMMHEL_00721 1.52e-264 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LPNMMHEL_00722 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LPNMMHEL_00723 3.55e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LPNMMHEL_00724 1.2e-87 yodB - - K - - - Transcriptional regulator, HxlR family
LPNMMHEL_00725 3.09e-122 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LPNMMHEL_00726 4.47e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPNMMHEL_00727 4.17e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LPNMMHEL_00728 2.58e-228 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LPNMMHEL_00729 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNMMHEL_00730 1.01e-157 csrR - - K - - - response regulator
LPNMMHEL_00731 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LPNMMHEL_00732 1.41e-52 - - - S - - - Psort location Cytoplasmic, score
LPNMMHEL_00733 9e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
LPNMMHEL_00734 3.76e-267 ylbM - - S - - - Belongs to the UPF0348 family
LPNMMHEL_00735 6.9e-178 yccK - - Q - - - ubiE/COQ5 methyltransferase family
LPNMMHEL_00736 1.18e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LPNMMHEL_00737 3.21e-142 yqeK - - H - - - Hydrolase, HD family
LPNMMHEL_00738 2.72e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LPNMMHEL_00739 3.95e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
LPNMMHEL_00740 2.04e-260 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
LPNMMHEL_00741 6.63e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
LPNMMHEL_00742 6.81e-221 ykcA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LPNMMHEL_00743 1.93e-243 mhqA_2 - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LPNMMHEL_00744 2.14e-157 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
LPNMMHEL_00745 2.49e-230 - - - C - - - Alcohol dehydrogenase GroES-like domain
LPNMMHEL_00746 2.37e-129 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LPNMMHEL_00747 1.02e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LPNMMHEL_00748 1.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LPNMMHEL_00749 7.46e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LPNMMHEL_00750 1.62e-165 - - - S - - - SseB protein N-terminal domain
LPNMMHEL_00751 5.3e-70 - - - - - - - -
LPNMMHEL_00752 1.27e-134 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
LPNMMHEL_00753 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LPNMMHEL_00754 2.02e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LPNMMHEL_00755 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
LPNMMHEL_00756 2.06e-103 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LPNMMHEL_00757 2.71e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LPNMMHEL_00758 2.07e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LPNMMHEL_00759 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPNMMHEL_00760 4.93e-153 ybhL - - S ko:K06890 - ko00000 Inhibitor of apoptosis-promoting Bax1
LPNMMHEL_00761 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LPNMMHEL_00762 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LPNMMHEL_00763 3.7e-148 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LPNMMHEL_00764 5.32e-73 ytpP - - CO - - - Thioredoxin
LPNMMHEL_00766 8.13e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LPNMMHEL_00767 4.51e-189 ytmP - - M - - - Choline/ethanolamine kinase
LPNMMHEL_00769 3.95e-273 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_00770 9.76e-172 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_00771 2.56e-98 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
LPNMMHEL_00772 5.77e-81 - - - S - - - YtxH-like protein
LPNMMHEL_00773 5.26e-205 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LPNMMHEL_00774 8.42e-232 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
LPNMMHEL_00775 5.98e-72 - - - S - - - Control of competence regulator ComK, YlbF/YmcA
LPNMMHEL_00776 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LPNMMHEL_00777 4.33e-197 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LPNMMHEL_00778 3.31e-98 argR1 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LPNMMHEL_00779 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LPNMMHEL_00781 1.97e-88 - - - - - - - -
LPNMMHEL_00782 1.16e-31 - - - - - - - -
LPNMMHEL_00783 3.67e-227 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
LPNMMHEL_00784 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
LPNMMHEL_00785 1.44e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LPNMMHEL_00786 1.13e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LPNMMHEL_00787 5.44e-175 yhfI - - S - - - Metallo-beta-lactamase superfamily
LPNMMHEL_00788 7.88e-121 traP 1.14.99.57, 6.2.1.3 - S ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 heme oxygenase (decyclizing) activity
LPNMMHEL_00789 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LPNMMHEL_00790 6.57e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_00791 1.57e-159 rrp1 - - K ko:K02483 - ko00000,ko02022 response regulator
LPNMMHEL_00792 1.58e-262 - - - T ko:K19168 - ko00000,ko02048 His Kinase A (phosphoacceptor) domain
LPNMMHEL_00793 1.54e-141 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LPNMMHEL_00794 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
LPNMMHEL_00795 1.37e-99 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
LPNMMHEL_00796 1.06e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LPNMMHEL_00797 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LPNMMHEL_00798 9.63e-130 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LPNMMHEL_00799 3.28e-233 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LPNMMHEL_00800 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LPNMMHEL_00801 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPNMMHEL_00802 1.63e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPNMMHEL_00803 3.46e-54 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPNMMHEL_00804 4.48e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LPNMMHEL_00805 5.81e-272 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LPNMMHEL_00806 2.66e-102 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LPNMMHEL_00807 3.87e-135 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LPNMMHEL_00808 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LPNMMHEL_00809 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LPNMMHEL_00810 1.02e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
LPNMMHEL_00811 9.5e-39 - - - - - - - -
LPNMMHEL_00812 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LPNMMHEL_00813 3.36e-61 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
LPNMMHEL_00815 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LPNMMHEL_00816 1.22e-307 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
LPNMMHEL_00817 2.41e-261 yueF - - S - - - AI-2E family transporter
LPNMMHEL_00818 1.09e-95 yjcF - - S - - - Acetyltransferase (GNAT) domain
LPNMMHEL_00819 3.19e-122 - - - - - - - -
LPNMMHEL_00820 2.23e-134 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LPNMMHEL_00821 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
LPNMMHEL_00822 0.0 frvR - - K ko:K02538,ko:K03483,ko:K09685,ko:K18531 - ko00000,ko03000 transcriptional antiterminator
LPNMMHEL_00823 6.46e-83 - - - - - - - -
LPNMMHEL_00824 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPNMMHEL_00825 1.68e-103 - - - F - - - Nucleoside 2-deoxyribosyltransferase
LPNMMHEL_00826 2.13e-172 - - - K ko:K03489 - ko00000,ko03000 UTRA
LPNMMHEL_00827 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNMMHEL_00828 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_00829 2.36e-111 - - - - - - - -
LPNMMHEL_00830 7.89e-66 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
LPNMMHEL_00831 2.62e-51 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_00832 3.09e-91 - - - S - - - DJ-1/PfpI family
LPNMMHEL_00833 9.4e-30 mutT 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 GDP-mannose mannosyl hydrolase activity
LPNMMHEL_00834 6.95e-53 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
LPNMMHEL_00835 7.59e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LPNMMHEL_00836 3.74e-302 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_00837 4.1e-152 - - - G - - - Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LPNMMHEL_00838 1.01e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LPNMMHEL_00839 3.24e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LPNMMHEL_00840 3.82e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LPNMMHEL_00841 6.47e-207 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
LPNMMHEL_00844 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LPNMMHEL_00845 1.52e-204 - - - - - - - -
LPNMMHEL_00846 6.85e-155 - - - - - - - -
LPNMMHEL_00847 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
LPNMMHEL_00848 3.49e-307 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LPNMMHEL_00849 2.22e-110 - - - - - - - -
LPNMMHEL_00850 0.0 strH 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Gram-positive signal peptide protein, YSIRK family
LPNMMHEL_00851 9.12e-249 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LPNMMHEL_00852 5.43e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
LPNMMHEL_00853 1.63e-280 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
LPNMMHEL_00854 2.26e-288 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LPNMMHEL_00855 0.0 bgaC 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
LPNMMHEL_00856 5.61e-108 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LPNMMHEL_00857 4.68e-206 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LPNMMHEL_00858 3.66e-187 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
LPNMMHEL_00859 2.72e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LPNMMHEL_00860 8.48e-284 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
LPNMMHEL_00861 7.51e-243 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LPNMMHEL_00862 3.92e-245 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LPNMMHEL_00863 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_00864 2.96e-78 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_00865 2.04e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
LPNMMHEL_00866 1.42e-240 - - - E - - - M42 glutamyl aminopeptidase
LPNMMHEL_00867 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPNMMHEL_00868 1.47e-211 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LPNMMHEL_00869 2.05e-225 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPNMMHEL_00870 4.65e-277 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LPNMMHEL_00871 8.49e-66 - - - - - - - -
LPNMMHEL_00872 2.21e-164 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
LPNMMHEL_00873 4.48e-91 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
LPNMMHEL_00874 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LPNMMHEL_00875 2.13e-36 - - - - - - - -
LPNMMHEL_00876 6.37e-82 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
LPNMMHEL_00877 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
LPNMMHEL_00878 2.21e-258 - - - S - - - Calcineurin-like phosphoesterase
LPNMMHEL_00879 6.42e-208 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LPNMMHEL_00880 5.17e-223 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LPNMMHEL_00881 5.51e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPNMMHEL_00882 9.96e-212 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
LPNMMHEL_00883 2.91e-277 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LPNMMHEL_00884 6.81e-86 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LPNMMHEL_00885 2.53e-206 CcmA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_00886 7.43e-144 - - - I - - - ABC-2 family transporter protein
LPNMMHEL_00887 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
LPNMMHEL_00888 1.02e-257 ald1 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LPNMMHEL_00889 1.06e-238 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LPNMMHEL_00890 0.0 - - - S - - - OPT oligopeptide transporter protein
LPNMMHEL_00891 3.4e-82 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
LPNMMHEL_00892 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LPNMMHEL_00893 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LPNMMHEL_00894 3.07e-187 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
LPNMMHEL_00895 1.37e-106 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
LPNMMHEL_00896 8.23e-126 - - - K ko:K18939 - ko00000,ko00002,ko03000 Bacterial regulatory proteins, tetR family
LPNMMHEL_00897 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNMMHEL_00898 2.39e-84 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNMMHEL_00899 3.54e-272 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNMMHEL_00900 4.16e-199 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LPNMMHEL_00901 0.0 msbA9 - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
LPNMMHEL_00902 0.0 cydD1 - - CO ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
LPNMMHEL_00903 1.06e-96 - - - S - - - NusG domain II
LPNMMHEL_00904 1.35e-208 - - - M - - - Peptidoglycan-binding domain 1 protein
LPNMMHEL_00905 9.41e-136 - - - S - - - Protein of unknown function (DUF1211)
LPNMMHEL_00906 8.07e-40 - - - - - - - -
LPNMMHEL_00907 1.9e-227 - - - C - - - Cytochrome bd terminal oxidase subunit II
LPNMMHEL_00908 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit I
LPNMMHEL_00909 3.26e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LPNMMHEL_00910 1.54e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LPNMMHEL_00911 1.36e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LPNMMHEL_00912 1.23e-96 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LPNMMHEL_00913 5.22e-163 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LPNMMHEL_00914 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPNMMHEL_00915 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPNMMHEL_00916 9.09e-260 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LPNMMHEL_00917 1.66e-42 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
LPNMMHEL_00919 1.02e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LPNMMHEL_00920 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LPNMMHEL_00921 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
LPNMMHEL_00922 2.99e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LPNMMHEL_00923 1.04e-177 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LPNMMHEL_00924 8.23e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
LPNMMHEL_00925 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LPNMMHEL_00926 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LPNMMHEL_00928 2.2e-174 labL - - S - - - Putative threonine/serine exporter
LPNMMHEL_00929 1.48e-104 - - - S - - - Threonine/Serine exporter, ThrE
LPNMMHEL_00930 1.53e-288 amd - - E - - - Peptidase family M20/M25/M40
LPNMMHEL_00931 6.29e-145 ypjH - - C ko:K08317 - ko00000,ko01000 dehydrogenase
LPNMMHEL_00933 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
LPNMMHEL_00934 1.38e-158 - - - S ko:K07090 - ko00000 membrane transporter protein
LPNMMHEL_00935 6.97e-133 - - - S - - - Protein of unknown function (DUF1211)
LPNMMHEL_00936 8.19e-212 - - - P - - - CorA-like Mg2+ transporter protein
LPNMMHEL_00937 3.84e-145 - - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_00939 2.37e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LPNMMHEL_00940 1.12e-67 - - - - - - - -
LPNMMHEL_00942 7.5e-53 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNMMHEL_00943 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LPNMMHEL_00944 6.62e-143 - - - S - - - Membrane
LPNMMHEL_00945 4.32e-133 - - - - - - - -
LPNMMHEL_00946 6.98e-155 - - - - - - - -
LPNMMHEL_00948 1.22e-138 - - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_00949 0.0 - - - EGP - - - Major Facilitator
LPNMMHEL_00950 2.07e-262 - - - - - - - -
LPNMMHEL_00951 1.19e-233 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LPNMMHEL_00952 4.43e-177 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LPNMMHEL_00953 1.11e-133 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LPNMMHEL_00954 7.1e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LPNMMHEL_00955 6.56e-181 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LPNMMHEL_00956 1.23e-149 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
LPNMMHEL_00957 4.72e-128 dpsB - - P - - - Belongs to the Dps family
LPNMMHEL_00958 2.09e-45 copZ - - P - - - Heavy-metal-associated domain
LPNMMHEL_00959 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
LPNMMHEL_00961 0.000666 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LPNMMHEL_00962 7.8e-282 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_00963 2.28e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LPNMMHEL_00964 1.02e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LPNMMHEL_00965 3.93e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNMMHEL_00967 2.34e-140 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
LPNMMHEL_00968 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
LPNMMHEL_00970 8.91e-306 - - - EGP - - - Major Facilitator
LPNMMHEL_00971 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LPNMMHEL_00972 5.44e-100 - - - K - - - Transcriptional activator, Rgg GadR MutR family
LPNMMHEL_00973 1.08e-54 - - - K - - - Transcriptional activator, Rgg GadR MutR family
LPNMMHEL_00974 1.35e-71 ps105 - - - - - - -
LPNMMHEL_00976 1.82e-161 kdgR - - K - - - FCD domain
LPNMMHEL_00977 6.9e-150 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
LPNMMHEL_00978 6.17e-183 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LPNMMHEL_00979 2.66e-35 - - - - - - - -
LPNMMHEL_00981 1.83e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
LPNMMHEL_00982 2.18e-156 azlC - - E - - - branched-chain amino acid
LPNMMHEL_00983 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
LPNMMHEL_00984 3.23e-92 - - - - - - - -
LPNMMHEL_00986 1.04e-14 - - - - - - - -
LPNMMHEL_00987 4.99e-72 - - - - - - - -
LPNMMHEL_00988 3.64e-70 - - - - - - - -
LPNMMHEL_00989 2.87e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LPNMMHEL_00990 2.76e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LPNMMHEL_00991 1.38e-84 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LPNMMHEL_00992 6.78e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LPNMMHEL_00993 1.03e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LPNMMHEL_00994 3.27e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
LPNMMHEL_00995 1.81e-88 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
LPNMMHEL_00996 3.98e-29 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LPNMMHEL_00997 8.44e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LPNMMHEL_00998 1.6e-206 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LPNMMHEL_00999 3.1e-216 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPNMMHEL_01000 7.56e-108 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LPNMMHEL_01001 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LPNMMHEL_01002 2.67e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LPNMMHEL_01003 3.9e-48 XK27_04345 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LPNMMHEL_01004 7.04e-217 - - - C - - - nadph quinone reductase
LPNMMHEL_01005 1.04e-99 - - - - - - - -
LPNMMHEL_01006 5.67e-191 - - - K - - - Helix-turn-helix
LPNMMHEL_01007 3.82e-92 - - - - - - - -
LPNMMHEL_01008 3.98e-240 - - - - - - - -
LPNMMHEL_01009 1.39e-200 - - - V - - - ABC transporter
LPNMMHEL_01010 6.52e-107 - - - FG - - - adenosine 5'-monophosphoramidase activity
LPNMMHEL_01011 3.28e-313 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
LPNMMHEL_01012 1.35e-150 - - - J - - - HAD-hyrolase-like
LPNMMHEL_01013 1.59e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LPNMMHEL_01014 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LPNMMHEL_01015 5.49e-58 - - - - - - - -
LPNMMHEL_01016 3.13e-170 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LPNMMHEL_01017 6.78e-220 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
LPNMMHEL_01018 1.42e-112 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
LPNMMHEL_01019 1.68e-134 - 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LPNMMHEL_01020 2.23e-50 - - - - - - - -
LPNMMHEL_01021 8.05e-88 - - - S - - - Protein of unknown function (DUF1093)
LPNMMHEL_01022 6.1e-27 - - - - - - - -
LPNMMHEL_01023 1.72e-64 - - - - - - - -
LPNMMHEL_01024 1.79e-59 - - - K - - - Acetyltransferase (GNAT) domain
LPNMMHEL_01027 5.15e-142 - - - S - - - Flavodoxin-like fold
LPNMMHEL_01028 1.48e-128 - - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_01029 2.69e-186 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
LPNMMHEL_01030 9.1e-138 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 Rossmann-like domain
LPNMMHEL_01031 1.97e-08 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 Rossmann-like domain
LPNMMHEL_01032 3.34e-245 XK27_00915 - - C - - - Luciferase-like monooxygenase
LPNMMHEL_01034 5.04e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
LPNMMHEL_01035 3.14e-181 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPNMMHEL_01036 4.83e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LPNMMHEL_01037 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LPNMMHEL_01038 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
LPNMMHEL_01039 2.55e-137 - - - - - - - -
LPNMMHEL_01041 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPNMMHEL_01042 8.13e-238 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LPNMMHEL_01043 4.11e-150 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LPNMMHEL_01044 7.02e-182 - - - K - - - SIS domain
LPNMMHEL_01045 2.64e-145 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
LPNMMHEL_01046 2.77e-226 - - - S - - - Membrane
LPNMMHEL_01047 5.31e-82 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
LPNMMHEL_01048 5.78e-287 inlJ - - M - - - MucBP domain
LPNMMHEL_01049 2.26e-169 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LPNMMHEL_01050 4.87e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_01051 1.83e-259 yacL - - S - - - domain protein
LPNMMHEL_01052 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LPNMMHEL_01053 4.85e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTPase
LPNMMHEL_01054 1.22e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
LPNMMHEL_01055 7.59e-49 - - - S - - - Protein of unknown function (DUF805)
LPNMMHEL_01056 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
LPNMMHEL_01057 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LPNMMHEL_01058 2.2e-253 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
LPNMMHEL_01059 6.1e-276 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LPNMMHEL_01060 1.17e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_01061 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LPNMMHEL_01062 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
LPNMMHEL_01063 5.12e-125 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
LPNMMHEL_01064 8.84e-120 ccpN - - K - - - Domain in cystathionine beta-synthase and other proteins.
LPNMMHEL_01068 1.21e-182 - - - S - - - CAAX protease self-immunity
LPNMMHEL_01070 5.62e-75 - - - - - - - -
LPNMMHEL_01072 3.38e-72 - - - S - - - Enterocin A Immunity
LPNMMHEL_01073 2.28e-59 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LPNMMHEL_01074 8.67e-34 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LPNMMHEL_01075 1.41e-06 - - - S - - - SpoVT / AbrB like domain
LPNMMHEL_01076 6.03e-17 doc - - S ko:K07341 - ko00000,ko02048 Prophage maintenance system killer protein
LPNMMHEL_01077 3.41e-230 ydhF - - S - - - Aldo keto reductase
LPNMMHEL_01078 2.03e-165 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNMMHEL_01079 1.05e-273 yqiG - - C - - - Oxidoreductase
LPNMMHEL_01080 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LPNMMHEL_01081 1.05e-171 - - - - - - - -
LPNMMHEL_01082 6.42e-28 - - - - - - - -
LPNMMHEL_01083 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LPNMMHEL_01084 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LPNMMHEL_01085 1.14e-72 - - - - - - - -
LPNMMHEL_01086 5.15e-305 - - - EGP - - - Major Facilitator Superfamily
LPNMMHEL_01087 0.0 sufI - - Q - - - Multicopper oxidase
LPNMMHEL_01088 1.53e-35 - - - - - - - -
LPNMMHEL_01089 7.75e-145 - - - P - - - Cation efflux family
LPNMMHEL_01090 7.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
LPNMMHEL_01091 3.81e-225 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LPNMMHEL_01092 1.69e-184 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LPNMMHEL_01093 2.78e-169 - 3.6.3.35 - P ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LPNMMHEL_01094 0.0 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family
LPNMMHEL_01095 6.85e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LPNMMHEL_01096 6.75e-215 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LPNMMHEL_01097 1.35e-150 - - - GM - - - NmrA-like family
LPNMMHEL_01098 7.77e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
LPNMMHEL_01099 7.04e-102 - - - - - - - -
LPNMMHEL_01100 3.23e-34 - - - M - - - domain protein
LPNMMHEL_01102 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LPNMMHEL_01103 8.03e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LPNMMHEL_01105 7.1e-49 - - - - - - - -
LPNMMHEL_01106 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LPNMMHEL_01107 2.05e-109 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
LPNMMHEL_01108 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LPNMMHEL_01109 6.15e-29 - - - - - - - -
LPNMMHEL_01110 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
LPNMMHEL_01111 1.97e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LPNMMHEL_01112 2.51e-103 yjhE - - S - - - Phage tail protein
LPNMMHEL_01113 1.8e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LPNMMHEL_01114 2e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LPNMMHEL_01115 4.03e-164 gpm2 - - G - - - Phosphoglycerate mutase family
LPNMMHEL_01116 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
LPNMMHEL_01117 2.68e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_01118 0.0 - - - E - - - Amino Acid
LPNMMHEL_01119 5.76e-210 - - - I - - - Diacylglycerol kinase catalytic domain
LPNMMHEL_01120 4.57e-304 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LPNMMHEL_01121 9.61e-208 nodB3 - - G - - - Polysaccharide deacetylase
LPNMMHEL_01122 0.0 - - - S - - - Glucosyl transferase GtrII
LPNMMHEL_01123 1.34e-299 - - - - - - - -
LPNMMHEL_01124 3.59e-123 - - - - - - - -
LPNMMHEL_01125 7.99e-233 - - - M - - - Peptidase_C39 like family
LPNMMHEL_01126 1.13e-87 - - - K - - - Tetracyclin repressor, C-terminal all-alpha domain
LPNMMHEL_01127 2.03e-73 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LPNMMHEL_01129 1.5e-75 - - - P - - - ABC-2 family transporter protein
LPNMMHEL_01130 5.51e-127 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LPNMMHEL_01131 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LPNMMHEL_01132 1.58e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LPNMMHEL_01133 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LPNMMHEL_01134 1.56e-275 - - - - - - - -
LPNMMHEL_01135 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNMMHEL_01136 8.23e-165 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LPNMMHEL_01137 1.42e-153 yleF - - K - - - Helix-turn-helix domain, rpiR family
LPNMMHEL_01138 9.64e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LPNMMHEL_01139 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
LPNMMHEL_01140 4.34e-75 cadC5 - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
LPNMMHEL_01141 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
LPNMMHEL_01142 2.43e-206 lysR5 - - K - - - LysR substrate binding domain
LPNMMHEL_01143 1.84e-260 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNMMHEL_01144 1.91e-46 - - - S - - - Phospholipase_D-nuclease N-terminal
LPNMMHEL_01145 1.71e-212 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_01146 3.78e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LPNMMHEL_01147 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LPNMMHEL_01149 1.75e-127 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
LPNMMHEL_01150 0.0 - - - - - - - -
LPNMMHEL_01151 1.64e-66 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
LPNMMHEL_01152 2.38e-78 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_01153 1.1e-61 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_01154 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
LPNMMHEL_01155 3.06e-193 - - - S - - - hydrolase
LPNMMHEL_01156 1.49e-58 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
LPNMMHEL_01157 1.15e-237 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
LPNMMHEL_01158 1.48e-109 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LPNMMHEL_01159 2.18e-177 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LPNMMHEL_01160 7.9e-196 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
LPNMMHEL_01161 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
LPNMMHEL_01162 8.75e-90 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LPNMMHEL_01163 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LPNMMHEL_01164 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
LPNMMHEL_01165 6.18e-255 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
LPNMMHEL_01166 6.31e-69 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
LPNMMHEL_01168 0.0 pip - - V ko:K01421 - ko00000 domain protein
LPNMMHEL_01169 6.39e-200 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LPNMMHEL_01170 5.84e-253 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LPNMMHEL_01171 1.75e-105 - - - - - - - -
LPNMMHEL_01172 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LPNMMHEL_01173 7.24e-23 - - - - - - - -
LPNMMHEL_01174 2.03e-130 - - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_01175 2.1e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
LPNMMHEL_01176 2.35e-132 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
LPNMMHEL_01177 1.03e-242 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
LPNMMHEL_01178 1.38e-97 - - - O - - - OsmC-like protein
LPNMMHEL_01183 2.58e-113 sip - - L - - - Phage integrase family
LPNMMHEL_01184 6.52e-115 sip - - L - - - Phage integrase family
LPNMMHEL_01185 2.46e-218 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LPNMMHEL_01186 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LPNMMHEL_01187 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LPNMMHEL_01188 9.19e-249 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LPNMMHEL_01189 2.29e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LPNMMHEL_01190 2.32e-190 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LPNMMHEL_01191 2.03e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
LPNMMHEL_01192 2.32e-79 yitW - - S - - - Iron-sulfur cluster assembly protein
LPNMMHEL_01193 1.06e-182 - - - - - - - -
LPNMMHEL_01194 4.61e-224 - - - - - - - -
LPNMMHEL_01195 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
LPNMMHEL_01196 4.56e-244 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LPNMMHEL_01197 3.82e-231 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
LPNMMHEL_01198 1.31e-215 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
LPNMMHEL_01199 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LPNMMHEL_01200 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LPNMMHEL_01201 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LPNMMHEL_01203 3.5e-112 ypmB - - S - - - Protein conserved in bacteria
LPNMMHEL_01204 3.29e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LPNMMHEL_01205 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LPNMMHEL_01206 3.19e-146 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
LPNMMHEL_01207 1.26e-146 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LPNMMHEL_01208 5.94e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LPNMMHEL_01209 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
LPNMMHEL_01210 5.12e-157 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LPNMMHEL_01211 6.54e-138 ypsA - - S - - - Belongs to the UPF0398 family
LPNMMHEL_01212 7.09e-88 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LPNMMHEL_01213 9.39e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LPNMMHEL_01214 1.22e-220 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
LPNMMHEL_01215 7.29e-46 - - - - - - - -
LPNMMHEL_01216 2.02e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LPNMMHEL_01217 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LPNMMHEL_01218 7.8e-206 lysR - - K - - - Transcriptional regulator
LPNMMHEL_01219 8.83e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPNMMHEL_01220 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPNMMHEL_01221 8.72e-52 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
LPNMMHEL_01222 3.39e-26 - - - S - - - Mga helix-turn-helix domain
LPNMMHEL_01223 1.78e-292 - - - S - - - Mga helix-turn-helix domain
LPNMMHEL_01224 1.91e-63 - - - - - - - -
LPNMMHEL_01225 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPNMMHEL_01226 1.21e-142 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
LPNMMHEL_01227 2.28e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
LPNMMHEL_01228 8.5e-61 - - - S - - - Family of unknown function (DUF5322)
LPNMMHEL_01229 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LPNMMHEL_01230 2.41e-106 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LPNMMHEL_01231 5.18e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LPNMMHEL_01232 1.05e-125 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LPNMMHEL_01233 1.64e-299 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
LPNMMHEL_01234 3.11e-228 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LPNMMHEL_01235 4.71e-301 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LPNMMHEL_01236 5.32e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LPNMMHEL_01237 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LPNMMHEL_01238 1.63e-199 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LPNMMHEL_01239 3.8e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LPNMMHEL_01240 1.19e-144 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LPNMMHEL_01241 2.03e-189 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Phosphate acetyl/butaryl transferase
LPNMMHEL_01242 6.41e-261 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Acetokinase family
LPNMMHEL_01243 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
LPNMMHEL_01244 5.29e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
LPNMMHEL_01245 1.24e-233 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
LPNMMHEL_01246 7.77e-282 bfmBB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
LPNMMHEL_01247 2.13e-227 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LPNMMHEL_01248 8.21e-250 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LPNMMHEL_01249 1.73e-66 - - - S - - - MazG-like family
LPNMMHEL_01250 0.0 FbpA - - K - - - Fibronectin-binding protein
LPNMMHEL_01251 2.95e-205 - - - S - - - EDD domain protein, DegV family
LPNMMHEL_01252 3.35e-129 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LPNMMHEL_01253 1.99e-260 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LPNMMHEL_01254 3.15e-277 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LPNMMHEL_01255 2.81e-142 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LPNMMHEL_01256 3.4e-294 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LPNMMHEL_01257 3.22e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LPNMMHEL_01258 4.89e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LPNMMHEL_01259 1.08e-157 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LPNMMHEL_01260 1.42e-169 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LPNMMHEL_01261 5.84e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LPNMMHEL_01262 6.09e-70 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
LPNMMHEL_01263 2.22e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LPNMMHEL_01264 2.92e-144 - - - C - - - Nitroreductase family
LPNMMHEL_01265 6.86e-83 - - - K - - - Acetyltransferase (GNAT) domain
LPNMMHEL_01266 5.88e-62 - - - K - - - Acetyltransferase (GNAT) domain
LPNMMHEL_01267 6.44e-242 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
LPNMMHEL_01268 2.9e-158 - - - T - - - Transcriptional regulatory protein, C terminal
LPNMMHEL_01269 3.48e-219 kinG - - T - - - Histidine kinase-like ATPases
LPNMMHEL_01270 2.68e-176 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_01271 0.0 XK27_05700 - - V ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
LPNMMHEL_01272 7.18e-79 - - - - - - - -
LPNMMHEL_01273 6.01e-269 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
LPNMMHEL_01274 9.27e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
LPNMMHEL_01275 2.6e-232 - - - K - - - LysR substrate binding domain
LPNMMHEL_01276 2.56e-217 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LPNMMHEL_01277 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
LPNMMHEL_01278 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LPNMMHEL_01279 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LPNMMHEL_01280 6.92e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LPNMMHEL_01281 5.38e-219 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LPNMMHEL_01282 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LPNMMHEL_01283 2.06e-119 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LPNMMHEL_01284 1.66e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
LPNMMHEL_01285 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LPNMMHEL_01286 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LPNMMHEL_01287 1.82e-186 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
LPNMMHEL_01288 2.05e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LPNMMHEL_01289 1.46e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LPNMMHEL_01290 8.99e-64 - - - K - - - Helix-turn-helix domain
LPNMMHEL_01291 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LPNMMHEL_01292 1.03e-54 yozE - - S - - - Belongs to the UPF0346 family
LPNMMHEL_01293 6.11e-111 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPNMMHEL_01294 3.18e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
LPNMMHEL_01295 2.81e-195 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
LPNMMHEL_01296 4.9e-190 WQ51_01275 - - S - - - EDD domain protein, DegV family
LPNMMHEL_01297 5.26e-148 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
LPNMMHEL_01298 2.03e-34 - - - T - - - PFAM SpoVT AbrB
LPNMMHEL_01300 2.85e-116 - - - - - - - -
LPNMMHEL_01301 1.15e-138 dgoD 4.2.1.6, 4.2.1.8 - M ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Mandelate racemase muconate lactonizing enzyme
LPNMMHEL_01302 4.81e-118 dgoD 4.2.1.6, 4.2.1.8 - M ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Mandelate racemase muconate lactonizing enzyme
LPNMMHEL_01303 1.74e-299 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LPNMMHEL_01304 4.82e-60 sgcB 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_01305 1.69e-102 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPNMMHEL_01306 5.89e-138 - 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
LPNMMHEL_01307 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPNMMHEL_01308 5.54e-59 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
LPNMMHEL_01309 1.22e-64 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_01310 0.0 bgl 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNMMHEL_01311 2.12e-195 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
LPNMMHEL_01312 1.62e-313 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
LPNMMHEL_01313 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
LPNMMHEL_01314 4.29e-226 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_01315 1.15e-59 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_01316 1.1e-172 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LPNMMHEL_01317 2.36e-102 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
LPNMMHEL_01319 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LPNMMHEL_01320 5.31e-69 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_01321 7.5e-59 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPNMMHEL_01322 3.66e-183 rdrB - - K ko:K02444,ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LPNMMHEL_01323 6.73e-208 - - - J - - - Methyltransferase domain
LPNMMHEL_01324 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LPNMMHEL_01326 5.45e-146 alkD - - L - - - DNA alkylation repair enzyme
LPNMMHEL_01327 7.16e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LPNMMHEL_01328 3.28e-61 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LPNMMHEL_01329 2.15e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
LPNMMHEL_01330 2.63e-27 - - - - - - - -
LPNMMHEL_01332 2.08e-214 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
LPNMMHEL_01333 4.19e-31 - - - - - - - -
LPNMMHEL_01334 1.4e-26 - - - S - - - Family of unknown function (DUF5388)
LPNMMHEL_01335 3.31e-137 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
LPNMMHEL_01336 1.34e-97 - - - S - - - Replication initiator protein A (RepA) N-terminus
LPNMMHEL_01348 2.2e-60 - - - M - - - Domain of unknown function (DUF5011)
LPNMMHEL_01349 9.1e-12 - - - S - - - Protein of unknown function (DUF3801)
LPNMMHEL_01350 3.84e-157 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
LPNMMHEL_01351 1.74e-21 - - - - - - - -
LPNMMHEL_01352 2.06e-33 - - - - - - - -
LPNMMHEL_01353 2.54e-21 - - - U - - - PrgI family protein
LPNMMHEL_01354 6.91e-314 - - - U - - - AAA-like domain
LPNMMHEL_01355 8.57e-43 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
LPNMMHEL_01359 1.21e-74 - - - L - - - IrrE N-terminal-like domain
LPNMMHEL_01361 1.29e-05 - - - S - - - Bacterial mobilisation protein (MobC)
LPNMMHEL_01362 3.51e-114 - - - U - - - Relaxase/Mobilisation nuclease domain
LPNMMHEL_01363 1.96e-81 - - - L - - - Protein of unknown function (DUF3991)
LPNMMHEL_01365 2.4e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LPNMMHEL_01366 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LPNMMHEL_01367 4.81e-127 - - - - - - - -
LPNMMHEL_01368 8.44e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LPNMMHEL_01369 9.61e-246 - - - S - - - Protein of unknown function C-terminal (DUF3324)
LPNMMHEL_01370 8.02e-114 - - - - - - - -
LPNMMHEL_01371 1.43e-25 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LPNMMHEL_01372 5.98e-150 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LPNMMHEL_01373 7.86e-202 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LPNMMHEL_01374 1.25e-201 - - - I - - - alpha/beta hydrolase fold
LPNMMHEL_01375 6.45e-41 - - - - - - - -
LPNMMHEL_01376 6.11e-96 - - - - - - - -
LPNMMHEL_01377 6.65e-198 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
LPNMMHEL_01378 4.14e-163 citR - - K - - - FCD
LPNMMHEL_01379 0.0 oadA 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Conserved carboxylase domain
LPNMMHEL_01380 1.89e-120 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LPNMMHEL_01381 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
LPNMMHEL_01382 7.46e-201 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
LPNMMHEL_01383 3.41e-65 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
LPNMMHEL_01384 1.28e-229 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LPNMMHEL_01385 3.26e-07 - - - - - - - -
LPNMMHEL_01386 1.13e-250 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
LPNMMHEL_01387 2.06e-60 oadG - - I - - - Biotin-requiring enzyme
LPNMMHEL_01388 9.08e-71 - - - - - - - -
LPNMMHEL_01389 1.43e-307 citM - - C ko:K03300 - ko00000 Citrate transporter
LPNMMHEL_01390 3.61e-55 - - - - - - - -
LPNMMHEL_01391 2.68e-135 kptA - - J ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LPNMMHEL_01392 2.1e-114 - - - K - - - GNAT family
LPNMMHEL_01393 3.85e-137 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
LPNMMHEL_01394 1.13e-75 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LPNMMHEL_01395 5.7e-112 ORF00048 - - - - - - -
LPNMMHEL_01396 2.38e-172 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LPNMMHEL_01397 4.57e-50 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPNMMHEL_01398 2.36e-167 rpl - - K - - - Helix-turn-helix domain, rpiR family
LPNMMHEL_01399 1.88e-223 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LPNMMHEL_01400 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPNMMHEL_01401 5.24e-116 - - - - - - - -
LPNMMHEL_01402 4.42e-154 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LPNMMHEL_01403 2.66e-233 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LPNMMHEL_01404 2.87e-289 - - - EK - - - Aminotransferase, class I
LPNMMHEL_01405 8.49e-211 - - - K - - - LysR substrate binding domain
LPNMMHEL_01406 3.81e-115 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LPNMMHEL_01407 7.22e-197 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LPNMMHEL_01408 4.48e-161 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
LPNMMHEL_01409 3.43e-138 - - - S - - - Protein of unknown function (DUF1275)
LPNMMHEL_01410 1.99e-16 - - - - - - - -
LPNMMHEL_01411 4.04e-79 - - - - - - - -
LPNMMHEL_01412 6.84e-186 - - - S - - - hydrolase
LPNMMHEL_01413 6.25e-246 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
LPNMMHEL_01414 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
LPNMMHEL_01415 6.41e-92 - - - K - - - MarR family
LPNMMHEL_01416 3.47e-147 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LPNMMHEL_01418 1.15e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LPNMMHEL_01419 6.52e-222 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 Voltage-dependent anion channel
LPNMMHEL_01420 1.62e-192 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LPNMMHEL_01421 0.0 - - - L - - - DNA helicase
LPNMMHEL_01422 4.1e-130 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LPNMMHEL_01423 0.0 - - - EGP - - - Major Facilitator Superfamily
LPNMMHEL_01424 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LPNMMHEL_01425 1.4e-208 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNMMHEL_01426 3.01e-227 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNMMHEL_01427 4.99e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNMMHEL_01428 3.15e-230 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNMMHEL_01429 8.42e-149 gpm5 - - G - - - Phosphoglycerate mutase family
LPNMMHEL_01430 6.56e-64 - - - K - - - sequence-specific DNA binding
LPNMMHEL_01431 3.49e-48 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
LPNMMHEL_01432 3.64e-160 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LPNMMHEL_01433 3.45e-105 ccl - - S - - - QueT transporter
LPNMMHEL_01434 1.5e-169 - - - E - - - lipolytic protein G-D-S-L family
LPNMMHEL_01435 3.14e-151 epsB - - M - - - biosynthesis protein
LPNMMHEL_01436 6.9e-143 ywqD - - D - - - Capsular exopolysaccharide family
LPNMMHEL_01437 5.64e-109 cps2J - - S - - - Polysaccharide biosynthesis protein
LPNMMHEL_01438 1.52e-33 - - - S ko:K07011 - ko00000 Pfam Glycosyl transferase family 2
LPNMMHEL_01439 5.36e-45 - - - M - - - Glycosyl transferases group 1
LPNMMHEL_01440 2.06e-21 - - - S - - - Glycosyl transferase family 2
LPNMMHEL_01441 8.75e-84 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
LPNMMHEL_01443 1.45e-52 - - - M - - - Glycosyl transferases group 1
LPNMMHEL_01444 1.22e-76 - - - S - - - SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
LPNMMHEL_01445 4.22e-41 - - - - - - - -
LPNMMHEL_01446 1.89e-133 - - - - - - - -
LPNMMHEL_01447 3.79e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNMMHEL_01448 4.58e-305 - - - EGP - - - Major Facilitator
LPNMMHEL_01449 0.0 pbpC - - M ko:K21467 - ko00000,ko01011 NTF2-like N-terminal transpeptidase domain
LPNMMHEL_01450 5.13e-55 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
LPNMMHEL_01451 1.34e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPNMMHEL_01452 1.41e-214 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
LPNMMHEL_01453 1.39e-197 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LPNMMHEL_01454 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LPNMMHEL_01455 3.66e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LPNMMHEL_01456 8.47e-240 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
LPNMMHEL_01457 1.16e-45 - - - - - - - -
LPNMMHEL_01458 0.0 - - - E - - - Amino acid permease
LPNMMHEL_01459 3.14e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LPNMMHEL_01460 4.09e-136 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LPNMMHEL_01461 1.68e-191 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LPNMMHEL_01462 5.11e-107 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
LPNMMHEL_01463 1.19e-166 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LPNMMHEL_01464 2.8e-144 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
LPNMMHEL_01465 3.99e-313 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LPNMMHEL_01466 4.57e-123 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LPNMMHEL_01468 3.82e-141 - - - S ko:K03824 - ko00000,ko01000 Acetyltransferase (GNAT) family
LPNMMHEL_01469 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LPNMMHEL_01470 4.62e-66 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LPNMMHEL_01473 6.22e-243 - - - K - - - DNA-binding helix-turn-helix protein
LPNMMHEL_01474 1.17e-77 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LPNMMHEL_01475 2.7e-62 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
LPNMMHEL_01476 4.91e-55 - - - - - - - -
LPNMMHEL_01477 2.02e-245 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LPNMMHEL_01479 1.32e-71 - - - - - - - -
LPNMMHEL_01480 1.03e-103 - - - - - - - -
LPNMMHEL_01481 5.77e-267 XK27_05220 - - S - - - AI-2E family transporter
LPNMMHEL_01482 1.58e-33 - - - - - - - -
LPNMMHEL_01483 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LPNMMHEL_01484 8.86e-60 - - - - - - - -
LPNMMHEL_01485 8.47e-214 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
LPNMMHEL_01486 8.37e-116 - - - S - - - Flavin reductase like domain
LPNMMHEL_01487 6.83e-91 - - - - - - - -
LPNMMHEL_01488 3.12e-129 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LPNMMHEL_01489 1.7e-81 yeaO - - S - - - Protein of unknown function, DUF488
LPNMMHEL_01490 2.2e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LPNMMHEL_01491 4.86e-201 mleR - - K - - - LysR family
LPNMMHEL_01492 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
LPNMMHEL_01493 3.58e-217 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
LPNMMHEL_01494 8.23e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LPNMMHEL_01495 2.28e-113 - - - C - - - FMN binding
LPNMMHEL_01496 7.65e-223 - - - K ko:K20373,ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
LPNMMHEL_01497 0.0 - - - V - - - ABC transporter transmembrane region
LPNMMHEL_01498 0.0 pepF - - E - - - Oligopeptidase F
LPNMMHEL_01499 3.86e-78 - - - - - - - -
LPNMMHEL_01500 4.5e-165 - - - S - - - WxL domain surface cell wall-binding
LPNMMHEL_01501 1.99e-241 ynjC - - S - - - Cell surface protein
LPNMMHEL_01503 0.0 - - - L - - - Mga helix-turn-helix domain
LPNMMHEL_01504 3.07e-218 - - - S - - - Protein of unknown function (DUF805)
LPNMMHEL_01505 1.1e-76 - - - - - - - -
LPNMMHEL_01506 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LPNMMHEL_01507 1.77e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPNMMHEL_01508 1.58e-202 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LPNMMHEL_01509 6.39e-177 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
LPNMMHEL_01510 8.86e-62 - - - S - - - Thiamine-binding protein
LPNMMHEL_01511 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
LPNMMHEL_01512 4.77e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_01513 0.0 bmr3 - - EGP - - - Major Facilitator
LPNMMHEL_01515 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LPNMMHEL_01516 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LPNMMHEL_01517 1.35e-129 - - - - - - - -
LPNMMHEL_01518 3.66e-67 - - - - - - - -
LPNMMHEL_01519 2.19e-69 - - - - - - - -
LPNMMHEL_01520 8.92e-50 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_01521 3.28e-156 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LPNMMHEL_01522 4.71e-263 - - - S - - - Bacterial low temperature requirement A protein (LtrA)
LPNMMHEL_01523 5.25e-61 - - - - - - - -
LPNMMHEL_01524 2.84e-263 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
LPNMMHEL_01525 1.59e-28 yhjA - - K - - - CsbD-like
LPNMMHEL_01527 1.5e-44 - - - - - - - -
LPNMMHEL_01528 5.02e-52 - - - - - - - -
LPNMMHEL_01529 1.72e-286 - - - EGP - - - Transmembrane secretion effector
LPNMMHEL_01530 1.15e-279 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LPNMMHEL_01531 5.43e-191 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LPNMMHEL_01533 2.58e-54 - - - - - - - -
LPNMMHEL_01534 1.62e-294 - - - S - - - Membrane
LPNMMHEL_01535 5.2e-188 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LPNMMHEL_01536 0.0 - - - M - - - Cna protein B-type domain
LPNMMHEL_01537 9.63e-306 - - - - - - - -
LPNMMHEL_01538 0.0 - - - M - - - domain protein
LPNMMHEL_01539 1.38e-235 - - - M - - - domain protein
LPNMMHEL_01540 7.69e-134 - - - - - - - -
LPNMMHEL_01541 1.48e-290 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LPNMMHEL_01542 1.15e-261 - - - S - - - Protein of unknown function (DUF2974)
LPNMMHEL_01543 2.06e-143 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNMMHEL_01544 0.0 - - - M - - - Glycosyl hydrolases family 25
LPNMMHEL_01545 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LPNMMHEL_01546 1.07e-206 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
LPNMMHEL_01547 7.39e-253 - - - S - - - Protein conserved in bacteria
LPNMMHEL_01548 3.74e-75 - - - - - - - -
LPNMMHEL_01549 3.39e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LPNMMHEL_01550 6.97e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LPNMMHEL_01551 2.55e-212 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LPNMMHEL_01552 1.07e-205 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
LPNMMHEL_01553 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LPNMMHEL_01554 4.84e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LPNMMHEL_01555 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LPNMMHEL_01556 5.69e-102 - - - T - - - Sh3 type 3 domain protein
LPNMMHEL_01557 7.68e-174 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LPNMMHEL_01558 2.32e-188 - - - M - - - Glycosyltransferase like family 2
LPNMMHEL_01559 2.19e-174 - - - S - - - Protein of unknown function (DUF975)
LPNMMHEL_01560 4.42e-54 - - - - - - - -
LPNMMHEL_01561 2.53e-139 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LPNMMHEL_01562 5.84e-224 draG - - O - - - ADP-ribosylglycohydrolase
LPNMMHEL_01563 0.0 - - - S - - - ABC transporter
LPNMMHEL_01564 6.86e-174 ypaC - - Q - - - Methyltransferase domain
LPNMMHEL_01565 3.07e-53 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
LPNMMHEL_01566 3.21e-158 ciaR - - K ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
LPNMMHEL_01567 3.08e-93 - - - S - - - GtrA-like protein
LPNMMHEL_01568 0.0 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
LPNMMHEL_01569 8.07e-233 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
LPNMMHEL_01570 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
LPNMMHEL_01571 1.43e-223 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
LPNMMHEL_01572 9.65e-180 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_01573 2.78e-207 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LPNMMHEL_01574 2.07e-213 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_01575 3.73e-214 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
LPNMMHEL_01576 0.0 bglB 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
LPNMMHEL_01577 8.05e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
LPNMMHEL_01579 1.94e-251 - - - - - - - -
LPNMMHEL_01580 9.5e-199 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LPNMMHEL_01581 1.92e-153 - - - S - - - Psort location Cytoplasmic, score
LPNMMHEL_01582 7.44e-113 - - - S - - - Short repeat of unknown function (DUF308)
LPNMMHEL_01584 1.5e-156 yrkL - - S - - - Flavodoxin-like fold
LPNMMHEL_01585 2.23e-191 - - - I - - - alpha/beta hydrolase fold
LPNMMHEL_01586 3.1e-270 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
LPNMMHEL_01588 7.42e-112 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LPNMMHEL_01589 6.8e-21 - - - - - - - -
LPNMMHEL_01590 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
LPNMMHEL_01591 3.77e-269 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LPNMMHEL_01592 3.73e-150 - - - S - - - HAD hydrolase, family IA, variant
LPNMMHEL_01593 4.13e-181 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
LPNMMHEL_01594 1.25e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
LPNMMHEL_01595 1.3e-121 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
LPNMMHEL_01596 1.03e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
LPNMMHEL_01597 7.11e-225 lacC 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LPNMMHEL_01598 4.48e-160 - - - S - - - Domain of unknown function (DUF4867)
LPNMMHEL_01599 9.83e-37 - - - - - - - -
LPNMMHEL_01600 0.0 gatC - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LPNMMHEL_01601 2.68e-67 - 2.7.1.204 - G ko:K20113 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_01602 3.22e-109 - 2.7.1.204 - G ko:K20112 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPNMMHEL_01605 3.94e-250 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LPNMMHEL_01606 1.39e-217 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LPNMMHEL_01607 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LPNMMHEL_01608 4.24e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LPNMMHEL_01609 6.67e-282 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LPNMMHEL_01610 6.22e-174 - - - M - - - Glycosyltransferase like family 2
LPNMMHEL_01611 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPNMMHEL_01612 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
LPNMMHEL_01613 7.75e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LPNMMHEL_01614 1.48e-144 ung2 - - L - - - Uracil-DNA glycosylase
LPNMMHEL_01615 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
LPNMMHEL_01616 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
LPNMMHEL_01618 5.67e-21 - - - M - - - Peptidoglycan-binding domain 1 protein
LPNMMHEL_01619 6.52e-153 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
LPNMMHEL_01620 2.22e-154 yqgG - - S ko:K07507 - ko00000,ko02000 MgtC family
LPNMMHEL_01621 9.75e-228 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
LPNMMHEL_01622 2.09e-315 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LPNMMHEL_01623 2.92e-203 - - - C - - - nadph quinone reductase
LPNMMHEL_01624 1.06e-69 ybjQ - - S - - - Belongs to the UPF0145 family
LPNMMHEL_01625 2.71e-159 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
LPNMMHEL_01626 1.79e-54 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LPNMMHEL_01627 6.05e-76 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LPNMMHEL_01628 1.12e-209 - - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_01629 5.16e-190 - - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
LPNMMHEL_01630 1.2e-95 - - - K - - - LytTr DNA-binding domain
LPNMMHEL_01631 1.57e-77 - - - S - - - Protein of unknown function (DUF3021)
LPNMMHEL_01632 4.51e-269 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
LPNMMHEL_01633 4.43e-146 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
LPNMMHEL_01634 0.0 - - - S - - - Protein of unknown function (DUF3800)
LPNMMHEL_01635 9.04e-317 yifK - - E ko:K03293 - ko00000 Amino acid permease
LPNMMHEL_01636 9.12e-201 - - - S - - - Aldo/keto reductase family
LPNMMHEL_01637 2.73e-147 ylbE - - GM - - - NAD(P)H-binding
LPNMMHEL_01638 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
LPNMMHEL_01639 1.37e-99 - - - O - - - OsmC-like protein
LPNMMHEL_01640 2.1e-89 - - - - - - - -
LPNMMHEL_01641 3.08e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
LPNMMHEL_01642 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LPNMMHEL_01643 2.66e-220 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
LPNMMHEL_01644 0.0 - - - E ko:K03294 - ko00000 Amino Acid
LPNMMHEL_01645 2.51e-282 sstT - - U ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LPNMMHEL_01646 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNMMHEL_01647 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LPNMMHEL_01648 5.43e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LPNMMHEL_01649 3.34e-286 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
LPNMMHEL_01650 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_01651 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_01652 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LPNMMHEL_01653 7.88e-211 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
LPNMMHEL_01654 1.83e-192 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
LPNMMHEL_01655 3.11e-30 - - - S - - - ECF-type riboflavin transporter, S component
LPNMMHEL_01656 3.7e-71 - - - S - - - ECF-type riboflavin transporter, S component
LPNMMHEL_01657 3.03e-186 CcmA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_01658 0.0 - - - - - - - -
LPNMMHEL_01659 6.94e-225 yicL - - EG - - - EamA-like transporter family
LPNMMHEL_01660 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
LPNMMHEL_01661 8.97e-312 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LPNMMHEL_01662 3.11e-73 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LPNMMHEL_01663 3.94e-127 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LPNMMHEL_01664 5.83e-73 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LPNMMHEL_01665 1.22e-219 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LPNMMHEL_01666 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LPNMMHEL_01667 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LPNMMHEL_01668 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LPNMMHEL_01669 1.9e-277 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LPNMMHEL_01670 4.81e-255 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LPNMMHEL_01671 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LPNMMHEL_01672 8.73e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LPNMMHEL_01673 6.31e-131 - - - M - - - Sortase family
LPNMMHEL_01674 2.13e-185 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPNMMHEL_01675 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
LPNMMHEL_01676 1.94e-86 spx2 - - P ko:K16509 - ko00000 ArsC family
LPNMMHEL_01677 1.42e-270 - - - - - - - -
LPNMMHEL_01678 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNMMHEL_01679 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LPNMMHEL_01680 2.05e-230 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
LPNMMHEL_01681 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LPNMMHEL_01682 3.47e-210 - - - GM - - - NmrA-like family
LPNMMHEL_01683 3.95e-297 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LPNMMHEL_01684 1.14e-182 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
LPNMMHEL_01685 8.74e-194 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LPNMMHEL_01686 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
LPNMMHEL_01687 3.23e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LPNMMHEL_01688 8.8e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LPNMMHEL_01689 6.98e-284 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LPNMMHEL_01690 9.65e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LPNMMHEL_01691 1.4e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
LPNMMHEL_01692 4.56e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
LPNMMHEL_01693 1.38e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPNMMHEL_01694 3.25e-225 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPNMMHEL_01695 2.44e-99 - - - K - - - Winged helix DNA-binding domain
LPNMMHEL_01696 3.93e-94 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LPNMMHEL_01699 5.52e-286 int3 - - L - - - Belongs to the 'phage' integrase family
LPNMMHEL_01701 2.14e-24 - - - - - - - -
LPNMMHEL_01702 2.2e-222 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LPNMMHEL_01703 6.47e-205 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LPNMMHEL_01704 4.94e-214 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LPNMMHEL_01705 8.6e-273 - - - EGP - - - Major Facilitator Superfamily
LPNMMHEL_01706 7.27e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LPNMMHEL_01707 7.27e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LPNMMHEL_01708 1.28e-203 - - - G - - - Xylose isomerase-like TIM barrel
LPNMMHEL_01709 4.74e-211 - - - K - - - Transcriptional regulator, LysR family
LPNMMHEL_01710 1.66e-117 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
LPNMMHEL_01711 0.0 ycaM - - E - - - amino acid
LPNMMHEL_01712 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LPNMMHEL_01713 2e-167 - - - S - - - WxL domain surface cell wall-binding
LPNMMHEL_01715 0.0 - - - - - - - -
LPNMMHEL_01716 7.85e-66 - - - - - - - -
LPNMMHEL_01717 4.96e-133 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LPNMMHEL_01718 6.64e-39 - - - - - - - -
LPNMMHEL_01719 2.04e-228 mhqA - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LPNMMHEL_01720 1.2e-61 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
LPNMMHEL_01721 0.0 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
LPNMMHEL_01722 2.42e-72 - - - S - - - Protein of unknown function (DUF1516)
LPNMMHEL_01723 1.55e-70 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LPNMMHEL_01724 5.79e-207 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 alcohol dehydrogenase
LPNMMHEL_01725 6.94e-106 - - - K - - - Transcriptional regulator
LPNMMHEL_01726 6.75e-57 - - - - - - - -
LPNMMHEL_01727 1.17e-245 ldhD3 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPNMMHEL_01728 3.37e-115 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
LPNMMHEL_01729 6.15e-260 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LPNMMHEL_01730 6.55e-57 - - - - - - - -
LPNMMHEL_01731 5.31e-266 mccF - - V - - - LD-carboxypeptidase
LPNMMHEL_01732 3.17e-235 yveB - - I - - - PAP2 superfamily
LPNMMHEL_01733 7.64e-57 - - - S - - - Protein of unknown function (DUF2089)
LPNMMHEL_01734 1.06e-49 - - - - - - - -
LPNMMHEL_01735 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
LPNMMHEL_01736 2.89e-105 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
LPNMMHEL_01739 8.65e-228 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LPNMMHEL_01740 4.18e-127 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
LPNMMHEL_01741 1.6e-103 - - - S - - - NusG domain II
LPNMMHEL_01742 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LPNMMHEL_01743 6.86e-187 cad - - S ko:K20379 ko02024,map02024 ko00000,ko00001 FMN_bind
LPNMMHEL_01744 6.32e-252 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LPNMMHEL_01745 2.85e-215 menA 2.5.1.74 - M ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
LPNMMHEL_01746 4.58e-220 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LPNMMHEL_01747 2.09e-30 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LPNMMHEL_01748 2.29e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LPNMMHEL_01749 8.15e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LPNMMHEL_01750 3.77e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
LPNMMHEL_01751 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
LPNMMHEL_01752 4.31e-83 - - - S - - - Domain of unknown function (DUF4430)
LPNMMHEL_01753 7.87e-125 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
LPNMMHEL_01754 1.4e-116 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
LPNMMHEL_01755 3.48e-86 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LPNMMHEL_01756 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
LPNMMHEL_01757 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
LPNMMHEL_01758 7.56e-75 - - - K - - - HxlR-like helix-turn-helix
LPNMMHEL_01759 9.7e-253 adh3 - - C - - - Zinc-binding dehydrogenase
LPNMMHEL_01760 6.47e-209 - - - S - - - reductase
LPNMMHEL_01761 1.68e-98 - - - K - - - helix_turn_helix, mercury resistance
LPNMMHEL_01762 0.0 - - - E - - - Amino acid permease
LPNMMHEL_01763 9.8e-282 - - - S ko:K07045 - ko00000 Amidohydrolase
LPNMMHEL_01764 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase, catalytic domain
LPNMMHEL_01765 3.29e-183 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
LPNMMHEL_01766 3.17e-185 - - - H - - - Protein of unknown function (DUF1698)
LPNMMHEL_01767 5.41e-191 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LPNMMHEL_01768 1.37e-246 pbpE - - V - - - Beta-lactamase
LPNMMHEL_01769 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LPNMMHEL_01770 5.36e-215 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
LPNMMHEL_01771 1.32e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LPNMMHEL_01772 4.89e-139 ydfF - - K - - - Transcriptional
LPNMMHEL_01773 7.42e-258 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
LPNMMHEL_01774 2.98e-64 yczG - - K - - - Helix-turn-helix domain
LPNMMHEL_01775 0.0 - - - L - - - Exonuclease
LPNMMHEL_01776 6.37e-169 lutC - - S ko:K00782 - ko00000 LUD domain
LPNMMHEL_01777 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
LPNMMHEL_01778 2.82e-189 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
LPNMMHEL_01779 2.39e-109 - - - - - - - -
LPNMMHEL_01780 6.31e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
LPNMMHEL_01781 8.51e-267 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LPNMMHEL_01782 2.3e-90 - - - S - - - Domain of unknown function (DUF3284)
LPNMMHEL_01784 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_01785 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LPNMMHEL_01786 1.68e-170 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
LPNMMHEL_01787 1.92e-122 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
LPNMMHEL_01788 0.0 - 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Helix-hairpin-helix containing domain
LPNMMHEL_01789 1.52e-103 - - - - - - - -
LPNMMHEL_01790 9.27e-77 - - - S - - - WxL domain surface cell wall-binding
LPNMMHEL_01791 2.79e-185 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
LPNMMHEL_01792 1.55e-169 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNMMHEL_01793 4.06e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
LPNMMHEL_01794 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
LPNMMHEL_01795 1.56e-230 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 carboxylic ester hydrolase activity
LPNMMHEL_01796 2.41e-58 - - - - - - - -
LPNMMHEL_01797 4.89e-122 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LPNMMHEL_01798 3.96e-256 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LPNMMHEL_01799 7.46e-157 XK27_05175 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
LPNMMHEL_01800 6.42e-101 - - - K - - - Transcriptional regulator
LPNMMHEL_01801 8.04e-230 ybcH - - D ko:K06889 - ko00000 Alpha beta
LPNMMHEL_01802 3.83e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
LPNMMHEL_01803 7.22e-199 dkgB - - S - - - reductase
LPNMMHEL_01804 5.55e-200 - - - - - - - -
LPNMMHEL_01805 6.16e-199 - - - S - - - Alpha beta hydrolase
LPNMMHEL_01806 4.49e-151 yviA - - S - - - Protein of unknown function (DUF421)
LPNMMHEL_01807 4.49e-97 - - - S - - - Protein of unknown function (DUF3290)
LPNMMHEL_01809 5.92e-284 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LPNMMHEL_01810 1.69e-112 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LPNMMHEL_01811 1.3e-136 yjbF - - S - - - SNARE associated Golgi protein
LPNMMHEL_01812 2.95e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LPNMMHEL_01813 1.59e-241 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LPNMMHEL_01814 7.74e-132 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LPNMMHEL_01815 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LPNMMHEL_01816 8.02e-118 - - - - - - - -
LPNMMHEL_01817 7.61e-269 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
LPNMMHEL_01818 9.28e-179 - - - V - - - ATPases associated with a variety of cellular activities
LPNMMHEL_01819 1.64e-249 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LPNMMHEL_01820 2.22e-163 - - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
LPNMMHEL_01821 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
LPNMMHEL_01822 4.78e-164 XK27_12140 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_01823 7.44e-257 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LPNMMHEL_01824 5.75e-209 - - - M - - - LPXTG cell wall anchor motif
LPNMMHEL_01825 2.44e-244 - - - E - - - Alpha/beta hydrolase family
LPNMMHEL_01826 1.08e-287 - - - C - - - Iron-containing alcohol dehydrogenase
LPNMMHEL_01827 2.84e-63 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
LPNMMHEL_01828 5.49e-88 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
LPNMMHEL_01829 5.76e-14 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LPNMMHEL_01830 5.89e-215 - - - S - - - Putative esterase
LPNMMHEL_01831 4.12e-253 - - - - - - - -
LPNMMHEL_01832 1.72e-135 - - - K - - - Transcriptional regulator, MarR family
LPNMMHEL_01833 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LPNMMHEL_01834 2.3e-106 - - - F - - - NUDIX domain
LPNMMHEL_01835 1.91e-167 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LPNMMHEL_01836 4.74e-30 - - - - - - - -
LPNMMHEL_01837 4.95e-206 - - - S - - - zinc-ribbon domain
LPNMMHEL_01838 4e-260 pbpX - - V - - - Beta-lactamase
LPNMMHEL_01839 4.01e-240 ydbI - - K - - - AI-2E family transporter
LPNMMHEL_01840 4.31e-166 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LPNMMHEL_01841 4.03e-85 gtcA2 - - S - - - Teichoic acid glycosylation protein
LPNMMHEL_01842 2.13e-90 - - - I - - - Diacylglycerol kinase catalytic domain
LPNMMHEL_01843 3.13e-68 - - - - - - - -
LPNMMHEL_01844 1.53e-88 - - - - - - - -
LPNMMHEL_01845 7.36e-94 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
LPNMMHEL_01846 7.39e-20 - - - - - - - -
LPNMMHEL_01847 7.99e-75 - - - S - - - acetyltransferase
LPNMMHEL_01848 0.0 yclK - - T - - - Histidine kinase
LPNMMHEL_01849 3.55e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
LPNMMHEL_01850 9.31e-93 - - - S - - - SdpI/YhfL protein family
LPNMMHEL_01853 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LPNMMHEL_01854 2.18e-212 arbZ - - I - - - Phosphate acyltransferases
LPNMMHEL_01855 1.63e-233 arbY - - M - - - family 8
LPNMMHEL_01856 1.17e-211 arbx - - M - - - Glycosyl transferase family 8
LPNMMHEL_01857 3.06e-190 arbV - - I - - - Phosphate acyltransferases
LPNMMHEL_01858 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LPNMMHEL_01859 4.05e-79 - - - - - - - -
LPNMMHEL_01860 3.06e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LPNMMHEL_01862 8.03e-24 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
LPNMMHEL_01863 3.85e-31 - - - - - - - -
LPNMMHEL_01865 2.86e-35 - - - - ko:K02245 - ko00000,ko00002,ko02044 -
LPNMMHEL_01866 7.91e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
LPNMMHEL_01867 2.91e-196 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
LPNMMHEL_01868 5.85e-169 yebC - - K - - - Transcriptional regulatory protein
LPNMMHEL_01869 3.35e-106 - - - S - - - VanZ like family
LPNMMHEL_01870 0.0 pepF2 - - E - - - Oligopeptidase F
LPNMMHEL_01872 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LPNMMHEL_01873 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPNMMHEL_01874 1.93e-217 ybbR - - S - - - YbbR-like protein
LPNMMHEL_01875 3.82e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LPNMMHEL_01876 4.45e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LPNMMHEL_01877 7.01e-236 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_01878 1.82e-144 - - - K - - - Transcriptional regulator
LPNMMHEL_01879 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
LPNMMHEL_01881 3.46e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_01882 2.88e-187 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LPNMMHEL_01883 1.44e-189 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LPNMMHEL_01884 9.1e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LPNMMHEL_01885 1.97e-124 - - - K - - - Cupin domain
LPNMMHEL_01886 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
LPNMMHEL_01887 5.54e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
LPNMMHEL_01888 8.14e-194 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LPNMMHEL_01889 8.04e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LPNMMHEL_01890 2.34e-271 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LPNMMHEL_01891 1.71e-209 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_01893 3.18e-106 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
LPNMMHEL_01894 5.84e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
LPNMMHEL_01895 1.45e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LPNMMHEL_01896 1.63e-202 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
LPNMMHEL_01897 7.57e-119 - - - - - - - -
LPNMMHEL_01898 3.63e-136 - - - K ko:K06977 - ko00000 Acetyltransferase (GNAT) domain
LPNMMHEL_01899 3.08e-248 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_01900 7.01e-213 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
LPNMMHEL_01901 1.1e-188 malF - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNMMHEL_01902 8.67e-312 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LPNMMHEL_01903 1.25e-306 YSH1 - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Metallo-beta-lactamase superfamily
LPNMMHEL_01904 1.13e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LPNMMHEL_01905 9.45e-23 - - - - - - - -
LPNMMHEL_01906 5.02e-20 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNMMHEL_01907 6.75e-153 - 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LPNMMHEL_01908 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LPNMMHEL_01909 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LPNMMHEL_01910 2.04e-94 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
LPNMMHEL_01911 7.56e-289 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
LPNMMHEL_01912 1.09e-226 yvdE - - K - - - helix_turn _helix lactose operon repressor
LPNMMHEL_01913 4.47e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LPNMMHEL_01914 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LPNMMHEL_01915 4.68e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
LPNMMHEL_01916 5.04e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LPNMMHEL_01917 0.0 eriC - - P ko:K03281 - ko00000 chloride
LPNMMHEL_01918 6.88e-73 - - - - - - - -
LPNMMHEL_01919 5.21e-293 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
LPNMMHEL_01920 9.74e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LPNMMHEL_01921 2.81e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LPNMMHEL_01922 2.16e-282 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LPNMMHEL_01923 2.1e-247 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LPNMMHEL_01924 5.52e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
LPNMMHEL_01925 7.35e-27 - - - M - - - Host cell surface-exposed lipoprotein
LPNMMHEL_01926 3.27e-256 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LPNMMHEL_01927 1.14e-60 - - - S - - - Bacteriophage holin
LPNMMHEL_01928 1.4e-58 - - - - - - - -
LPNMMHEL_01929 1.28e-50 - - - - - - - -
LPNMMHEL_01930 5.88e-94 - - - - - - - -
LPNMMHEL_01931 0.0 - - - LM - - - gp58-like protein
LPNMMHEL_01932 3.4e-162 - - - S - - - phage tail
LPNMMHEL_01933 0.0 - - - D - - - Phage tail tape measure protein
LPNMMHEL_01934 5.59e-30 - - - D - - - Phage tail tape measure protein
LPNMMHEL_01935 1.73e-81 - - - - - - - -
LPNMMHEL_01936 9.45e-152 - - - - - - - -
LPNMMHEL_01937 3.16e-89 - - - - - - - -
LPNMMHEL_01938 5.22e-75 - - - - - - - -
LPNMMHEL_01939 3.92e-76 - - - S - - - Phage head-tail joining protein
LPNMMHEL_01940 9.08e-71 - - - - - - - -
LPNMMHEL_01942 7.38e-274 - - - S - - - Phage capsid family
LPNMMHEL_01943 1.68e-164 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
LPNMMHEL_01944 2.31e-296 - - - S - - - Phage portal protein
LPNMMHEL_01945 0.0 - - - S - - - overlaps another CDS with the same product name
LPNMMHEL_01946 3.35e-81 - - - - - - - -
LPNMMHEL_01947 8.78e-89 - - - V - - - HNH endonuclease
LPNMMHEL_01948 1.66e-92 - - - S - - - Transcriptional regulator, RinA family
LPNMMHEL_01950 7.3e-137 - - - S - - - HNH endonuclease
LPNMMHEL_01952 2.93e-56 - - - - - - - -
LPNMMHEL_01953 2.04e-289 - - - S ko:K06919 - ko00000 Virulence-associated protein E
LPNMMHEL_01954 1.84e-192 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
LPNMMHEL_01955 1.41e-119 - - - - - - - -
LPNMMHEL_01956 9.31e-188 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LPNMMHEL_01957 1.32e-51 - - - - - - - -
LPNMMHEL_01958 1.07e-268 floL - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 SPFH domain / Band 7 family
LPNMMHEL_01959 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LPNMMHEL_01960 2.77e-291 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LPNMMHEL_01961 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
LPNMMHEL_01962 3.52e-192 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LPNMMHEL_01963 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
LPNMMHEL_01964 2.6e-96 usp1 - - T - - - Universal stress protein family
LPNMMHEL_01965 3.99e-176 sfsA - - S ko:K06206 - ko00000 Belongs to the SfsA family
LPNMMHEL_01966 9.19e-285 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
LPNMMHEL_01967 5.82e-189 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LPNMMHEL_01968 3.51e-216 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LPNMMHEL_01969 0.0 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LPNMMHEL_01970 1.66e-71 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
LPNMMHEL_01971 2.86e-118 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LPNMMHEL_01972 1.7e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LPNMMHEL_01973 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LPNMMHEL_01974 1.79e-75 - - - - - - - -
LPNMMHEL_01975 5.87e-109 - - - S - - - ASCH
LPNMMHEL_01976 5.36e-33 - - - - - - - -
LPNMMHEL_01977 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LPNMMHEL_01978 9.45e-261 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LPNMMHEL_01979 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LPNMMHEL_01980 3.18e-127 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LPNMMHEL_01981 1.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LPNMMHEL_01982 8.81e-288 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LPNMMHEL_01983 9.76e-229 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LPNMMHEL_01984 5.71e-213 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LPNMMHEL_01985 4.46e-183 terC - - P - - - Integral membrane protein TerC family
LPNMMHEL_01986 5.16e-142 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LPNMMHEL_01987 9.6e-217 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LPNMMHEL_01988 1.74e-152 - - - T - - - Transcriptional regulatory protein, C terminal
LPNMMHEL_01989 1.44e-201 - - - T - - - GHKL domain
LPNMMHEL_01990 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LPNMMHEL_01991 8.16e-203 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
LPNMMHEL_01992 2.05e-173 - - - F - - - deoxynucleoside kinase
LPNMMHEL_01993 2.93e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LPNMMHEL_01994 2.87e-219 - - - IQ - - - NAD dependent epimerase/dehydratase family
LPNMMHEL_01995 1.15e-196 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPNMMHEL_01996 1.89e-157 - - - G - - - alpha-ribazole phosphatase activity
LPNMMHEL_01997 4.62e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LPNMMHEL_01998 1.02e-158 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
LPNMMHEL_01999 5.99e-141 yktB - - S - - - Belongs to the UPF0637 family
LPNMMHEL_02000 2.76e-99 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
LPNMMHEL_02001 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
LPNMMHEL_02002 6.75e-215 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_02003 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
LPNMMHEL_02004 9.83e-148 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LPNMMHEL_02005 0.0 - - - EGP - - - Major Facilitator
LPNMMHEL_02006 1.65e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
LPNMMHEL_02007 1.23e-232 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNMMHEL_02008 4.73e-209 - - - S - - - Alpha beta hydrolase
LPNMMHEL_02009 2.73e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
LPNMMHEL_02010 3.24e-161 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_02011 1.32e-15 - - - - - - - -
LPNMMHEL_02012 5.83e-173 - - - - - - - -
LPNMMHEL_02013 1.5e-112 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_02014 2.48e-123 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LPNMMHEL_02015 7.79e-203 - - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
LPNMMHEL_02016 1.88e-252 - - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
LPNMMHEL_02018 1.08e-222 - - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNMMHEL_02021 1.4e-172 - - - - - - - -
LPNMMHEL_02022 2.33e-25 - - - E - - - Zn peptidase
LPNMMHEL_02023 1.51e-80 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNMMHEL_02026 4.03e-202 ps305 - - S - - - Protein of unknown function (Hypoth_ymh)
LPNMMHEL_02027 2.23e-179 - - - S - - - ORF6N domain
LPNMMHEL_02029 1.66e-59 - - - S - - - Domain of unknown function (DUF1883)
LPNMMHEL_02035 4.31e-178 - - - L - - - Helix-turn-helix domain
LPNMMHEL_02036 1.2e-197 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
LPNMMHEL_02038 5.45e-94 - - - - - - - -
LPNMMHEL_02039 1.23e-171 - - - - - - - -
LPNMMHEL_02042 2.76e-104 - - - - - - - -
LPNMMHEL_02044 6.7e-240 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
LPNMMHEL_02045 0.000324 - - - S - - - CsbD-like
LPNMMHEL_02046 6.79e-39 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
LPNMMHEL_02047 2.24e-264 - - - Q - - - Imidazolonepropionase and related amidohydrolases
LPNMMHEL_02048 1.31e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LPNMMHEL_02049 2.14e-237 - - - S - - - DUF218 domain
LPNMMHEL_02050 1.41e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
LPNMMHEL_02051 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
LPNMMHEL_02052 2.32e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
LPNMMHEL_02053 3.48e-103 ywiB - - S - - - Domain of unknown function (DUF1934)
LPNMMHEL_02054 1.15e-111 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LPNMMHEL_02055 3.42e-202 ybbB - - S - - - Protein of unknown function (DUF1211)
LPNMMHEL_02056 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LPNMMHEL_02057 5.48e-299 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LPNMMHEL_02058 6.55e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LPNMMHEL_02059 1.77e-300 int - - L - - - Belongs to the 'phage' integrase family
LPNMMHEL_02061 5.8e-83 - - - - - - - -
LPNMMHEL_02065 1.11e-190 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
LPNMMHEL_02066 1.18e-228 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
LPNMMHEL_02067 9.24e-189 - - - S - - - Sulfite exporter TauE/SafE
LPNMMHEL_02068 3.2e-203 - - - K - - - Sugar-specific transcriptional regulator TrmB
LPNMMHEL_02069 7.78e-150 - - - S - - - Zeta toxin
LPNMMHEL_02070 6.47e-208 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
LPNMMHEL_02071 1.19e-88 - - - - - - - -
LPNMMHEL_02072 5.62e-292 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LPNMMHEL_02073 3.38e-66 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_02074 1.9e-249 - - - GKT - - - transcriptional antiterminator
LPNMMHEL_02075 0.0 frdC 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
LPNMMHEL_02076 1.39e-80 - - - - - - - -
LPNMMHEL_02077 2.56e-104 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LPNMMHEL_02078 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LPNMMHEL_02079 1.52e-57 ykuJ - - S - - - Protein of unknown function (DUF1797)
LPNMMHEL_02080 8.08e-280 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LPNMMHEL_02082 1.58e-220 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LPNMMHEL_02083 4.62e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LPNMMHEL_02084 1.09e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LPNMMHEL_02086 1e-274 ybeC - - E - - - amino acid
LPNMMHEL_02087 2.97e-70 ybeC - - E - - - amino acid
LPNMMHEL_02088 8.3e-123 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
LPNMMHEL_02112 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LPNMMHEL_02113 1.7e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LPNMMHEL_02114 6.1e-143 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LPNMMHEL_02115 1.18e-250 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LPNMMHEL_02116 1.63e-236 - - - - - - - -
LPNMMHEL_02117 2.41e-203 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_02118 4.97e-81 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LPNMMHEL_02119 1.57e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LPNMMHEL_02120 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LPNMMHEL_02121 3.12e-68 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_02122 5.99e-243 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LPNMMHEL_02123 8.44e-130 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
LPNMMHEL_02124 3.82e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
LPNMMHEL_02125 2.81e-94 - - - - - - - -
LPNMMHEL_02126 1.57e-166 - - - - - - - -
LPNMMHEL_02127 0.0 cps2E - - M - - - Bacterial sugar transferase
LPNMMHEL_02128 9.34e-225 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
LPNMMHEL_02129 6.51e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LPNMMHEL_02130 1.44e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LPNMMHEL_02131 2.05e-189 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LPNMMHEL_02132 2.59e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_02133 2.65e-223 - - - - - - - -
LPNMMHEL_02135 3.91e-109 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LPNMMHEL_02136 2.69e-14 - - - - - - - -
LPNMMHEL_02137 7.28e-144 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
LPNMMHEL_02138 1.41e-89 - - - K - - - Acetyltransferase (GNAT) domain
LPNMMHEL_02139 2.08e-187 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
LPNMMHEL_02140 5.54e-270 - - - L - - - Helicase C-terminal domain protein
LPNMMHEL_02142 6.5e-109 - - - S - - - Siphovirus Gp157
LPNMMHEL_02145 9.66e-30 - - - - - - - -
LPNMMHEL_02148 4.68e-77 - - - S - - - Domain of unknown function (DUF771)
LPNMMHEL_02149 1.74e-151 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
LPNMMHEL_02151 8.81e-124 - - - K - - - Peptidase S24-like
LPNMMHEL_02154 1.64e-47 - - - - - - - -
LPNMMHEL_02155 2.81e-181 - - - - - - - -
LPNMMHEL_02156 8.96e-273 int3 - - L - - - Belongs to the 'phage' integrase family
LPNMMHEL_02158 5.97e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LPNMMHEL_02159 3.19e-105 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
LPNMMHEL_02160 7.91e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LPNMMHEL_02161 2.99e-248 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LPNMMHEL_02162 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LPNMMHEL_02163 2.56e-111 - - - S - - - Short repeat of unknown function (DUF308)
LPNMMHEL_02164 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LPNMMHEL_02165 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LPNMMHEL_02166 1.99e-153 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
LPNMMHEL_02167 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
LPNMMHEL_02168 2.43e-117 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_02169 5.51e-214 - - - T - - - His Kinase A (phosphoacceptor) domain
LPNMMHEL_02170 6.38e-148 - - - T - - - Transcriptional regulatory protein, C terminal
LPNMMHEL_02171 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LPNMMHEL_02172 1.43e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LPNMMHEL_02173 6.29e-250 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LPNMMHEL_02174 7.94e-202 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LPNMMHEL_02175 8.27e-223 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LPNMMHEL_02176 3.07e-50 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
LPNMMHEL_02177 2.13e-49 - - - - - - - -
LPNMMHEL_02178 0.0 yvlB - - S - - - Putative adhesin
LPNMMHEL_02179 3.82e-156 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
LPNMMHEL_02180 2.49e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LPNMMHEL_02181 9.06e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LPNMMHEL_02182 3.55e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
LPNMMHEL_02183 4.48e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LPNMMHEL_02184 1.76e-196 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LPNMMHEL_02185 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNMMHEL_02186 1.83e-168 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LPNMMHEL_02187 7.77e-259 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
LPNMMHEL_02189 1.28e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 ABC transporter
LPNMMHEL_02190 8.69e-239 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LPNMMHEL_02191 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LPNMMHEL_02192 3.24e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LPNMMHEL_02193 4.32e-104 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
LPNMMHEL_02194 2.33e-301 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
LPNMMHEL_02195 2.93e-151 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
LPNMMHEL_02196 7.95e-317 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LPNMMHEL_02197 5.55e-245 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LPNMMHEL_02198 1.05e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LPNMMHEL_02199 3.46e-136 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LPNMMHEL_02200 1.33e-168 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
LPNMMHEL_02201 3.01e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LPNMMHEL_02202 2.38e-310 ymfH - - S - - - Peptidase M16
LPNMMHEL_02203 2.21e-294 ymfF - - S - - - Peptidase M16 inactive domain protein
LPNMMHEL_02204 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LPNMMHEL_02205 4.04e-94 - - - S - - - Protein of unknown function (DUF1149)
LPNMMHEL_02206 3.21e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LPNMMHEL_02207 1.99e-199 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
LPNMMHEL_02208 1.94e-219 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LPNMMHEL_02209 4.94e-245 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LPNMMHEL_02210 4.12e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LPNMMHEL_02211 4.71e-81 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LPNMMHEL_02212 2.3e-254 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
LPNMMHEL_02213 1.09e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LPNMMHEL_02214 2.24e-148 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
LPNMMHEL_02215 9.8e-259 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LPNMMHEL_02216 2.88e-218 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LPNMMHEL_02217 1.05e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LPNMMHEL_02218 1.19e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LPNMMHEL_02219 7.28e-138 - - - S - - - CYTH
LPNMMHEL_02220 6.41e-148 yjbH - - Q - - - Thioredoxin
LPNMMHEL_02221 1.72e-272 coiA - - S ko:K06198 - ko00000 Competence protein
LPNMMHEL_02222 3.93e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
LPNMMHEL_02223 5.05e-52 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
LPNMMHEL_02224 0.0 cpdA - - S - - - Calcineurin-like phosphoesterase
LPNMMHEL_02225 9.02e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LPNMMHEL_02228 9.78e-112 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LPNMMHEL_02229 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LPNMMHEL_02230 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LPNMMHEL_02232 2.55e-121 - - - F - - - NUDIX domain
LPNMMHEL_02233 3.37e-183 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LPNMMHEL_02234 9.15e-45 yhcC - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
LPNMMHEL_02235 5.43e-166 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LPNMMHEL_02236 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LPNMMHEL_02237 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LPNMMHEL_02238 7.4e-155 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LPNMMHEL_02239 7.54e-155 - - - S - - - Domain of unknown function (DUF4811)
LPNMMHEL_02240 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
LPNMMHEL_02241 4.66e-105 - - - K - - - MerR HTH family regulatory protein
LPNMMHEL_02242 0.0 mdr - - EGP - - - Major Facilitator
LPNMMHEL_02243 7.89e-268 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LPNMMHEL_02244 1.98e-91 - - - - - - - -
LPNMMHEL_02247 3.38e-234 - - - S - - - endonuclease exonuclease phosphatase family protein
LPNMMHEL_02248 8.76e-177 XK27_08455 - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LPNMMHEL_02249 1.56e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
LPNMMHEL_02250 1.37e-104 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LPNMMHEL_02251 3.72e-210 - - - K - - - Helix-turn-helix domain, rpiR family
LPNMMHEL_02252 5.83e-197 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LPNMMHEL_02253 6.03e-247 - - - V - - - Beta-lactamase
LPNMMHEL_02254 2.53e-242 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LPNMMHEL_02255 3.41e-186 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
LPNMMHEL_02256 5.44e-174 - - - F - - - NUDIX domain
LPNMMHEL_02257 1.09e-138 pncA - - Q - - - Isochorismatase family
LPNMMHEL_02258 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LPNMMHEL_02259 4.95e-269 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
LPNMMHEL_02261 1.99e-187 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
LPNMMHEL_02262 4.75e-101 - - - - - - - -
LPNMMHEL_02264 5.33e-103 - - - - - - - -
LPNMMHEL_02265 2.45e-23 - - - - - - - -
LPNMMHEL_02266 2.32e-46 - - - - - - - -
LPNMMHEL_02267 1.5e-23 - - - - - - - -
LPNMMHEL_02268 0.0 - - - L - - - Protein of unknown function (DUF3991)
LPNMMHEL_02270 7.86e-285 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
LPNMMHEL_02277 1.19e-235 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 cysteine-type peptidase activity
LPNMMHEL_02278 3.41e-91 - - - S - - - COG0433 Predicted ATPase
LPNMMHEL_02279 9.64e-135 - - - EG - - - EamA-like transporter family
LPNMMHEL_02280 1.54e-25 - - - EG - - - EamA-like transporter family
LPNMMHEL_02281 7.82e-97 - - - L - - - NUDIX domain
LPNMMHEL_02282 8.13e-82 - - - - - - - -
LPNMMHEL_02283 9.67e-250 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LPNMMHEL_02284 1.46e-240 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LPNMMHEL_02285 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LPNMMHEL_02286 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LPNMMHEL_02287 4.4e-116 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LPNMMHEL_02288 3.04e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LPNMMHEL_02289 3.48e-215 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPNMMHEL_02290 3.52e-176 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LPNMMHEL_02292 0.000164 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
LPNMMHEL_02293 9.81e-19 - - - M - - - LPXTG cell wall anchor motif
LPNMMHEL_02294 4.1e-162 - - - M - - - domain protein
LPNMMHEL_02295 0.0 yvcC - - M - - - Cna protein B-type domain
LPNMMHEL_02296 7.58e-134 tnpR1 - - L - - - Resolvase, N terminal domain
LPNMMHEL_02297 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LPNMMHEL_02298 4.8e-66 licB2 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_02299 3.21e-268 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_02300 1.54e-75 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
LPNMMHEL_02301 0.0 - 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNMMHEL_02302 1.38e-123 - - - - - - - -
LPNMMHEL_02303 1.89e-167 - - - S - - - Protein of unknown function C-terminus (DUF2399)
LPNMMHEL_02304 0.0 - - - D - - - Putative exonuclease SbcCD, C subunit
LPNMMHEL_02305 5.02e-176 - - - - - - - -
LPNMMHEL_02306 1.38e-284 - - - - - - - -
LPNMMHEL_02307 1.83e-61 - - - S - - - Protein of unknown function (DUF2568)
LPNMMHEL_02308 1.79e-87 - - - K - - - helix_turn_helix, mercury resistance
LPNMMHEL_02309 1.89e-275 - - - - - - - -
LPNMMHEL_02311 1.21e-06 - - - - - - - -
LPNMMHEL_02313 2.94e-99 - - - L - - - Initiator Replication protein
LPNMMHEL_02315 5.52e-121 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LPNMMHEL_02316 2.44e-173 - - - D - - - Psort location Cytoplasmic, score
LPNMMHEL_02317 1.86e-63 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LPNMMHEL_02318 2.04e-47 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LPNMMHEL_02319 5.49e-261 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNMMHEL_02320 8.42e-135 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
LPNMMHEL_02321 3.42e-198 degV - - S - - - Uncharacterised protein, DegV family COG1307
LPNMMHEL_02322 1.76e-114 - - - K - - - Acetyltransferase (GNAT) domain
LPNMMHEL_02323 1.14e-174 - - - K - - - Acetyltransferase (GNAT) domain
LPNMMHEL_02324 8.39e-144 - - - GM - - - NAD(P)H-binding
LPNMMHEL_02325 1.07e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
LPNMMHEL_02326 5.48e-102 yphH - - S - - - Cupin domain
LPNMMHEL_02327 1.99e-205 - - - K - - - Transcriptional regulator
LPNMMHEL_02328 9.68e-173 zmp3 - - O - - - Zinc-dependent metalloprotease
LPNMMHEL_02330 1.04e-168 - - - K - - - DeoR C terminal sensor domain
LPNMMHEL_02332 5.24e-66 lciIC - - K - - - Helix-turn-helix domain
LPNMMHEL_02333 9.33e-122 yjdB - - S - - - Domain of unknown function (DUF4767)
LPNMMHEL_02334 7.28e-243 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
LPNMMHEL_02335 8.33e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNMMHEL_02336 3.06e-204 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
LPNMMHEL_02338 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LPNMMHEL_02339 3.81e-172 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_02340 4.51e-41 - - - - - - - -
LPNMMHEL_02341 1.21e-304 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LPNMMHEL_02342 1.26e-44 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
LPNMMHEL_02343 3.71e-94 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNMMHEL_02344 1.23e-113 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPNMMHEL_02345 2.23e-181 - - - M - - - Glycosyltransferase like family 2
LPNMMHEL_02346 8.47e-207 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
LPNMMHEL_02347 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
LPNMMHEL_02348 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNMMHEL_02349 2.65e-67 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
LPNMMHEL_02350 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LPNMMHEL_02352 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LPNMMHEL_02353 5.08e-222 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LPNMMHEL_02354 7.21e-245 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LPNMMHEL_02355 3.03e-261 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LPNMMHEL_02356 4.95e-146 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LPNMMHEL_02357 1.82e-233 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LPNMMHEL_02358 4.38e-113 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LPNMMHEL_02359 9.93e-130 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
LPNMMHEL_02360 8.46e-84 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
LPNMMHEL_02361 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LPNMMHEL_02362 1.66e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LPNMMHEL_02363 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LPNMMHEL_02364 3.56e-189 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
LPNMMHEL_02365 6.15e-62 yktA - - S - - - Belongs to the UPF0223 family
LPNMMHEL_02366 7.16e-201 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
LPNMMHEL_02367 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
LPNMMHEL_02368 0.0 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LPNMMHEL_02369 1.15e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
LPNMMHEL_02370 1.42e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
LPNMMHEL_02371 5.13e-112 - - - S - - - E1-E2 ATPase
LPNMMHEL_02372 4.82e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LPNMMHEL_02373 1.73e-63 - - - - - - - -
LPNMMHEL_02374 1.3e-94 - - - - - - - -
LPNMMHEL_02375 2.02e-43 ykzG - - S - - - Belongs to the UPF0356 family
LPNMMHEL_02376 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LPNMMHEL_02377 4.67e-232 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LPNMMHEL_02378 2.86e-312 - - - S - - - Sterol carrier protein domain
LPNMMHEL_02379 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LPNMMHEL_02380 1.62e-151 - - - S - - - repeat protein
LPNMMHEL_02381 4.69e-159 pgm6 - - G - - - phosphoglycerate mutase
LPNMMHEL_02382 7.55e-311 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LPNMMHEL_02383 0.0 uvrA2 - - L - - - ABC transporter
LPNMMHEL_02384 2.45e-75 XK27_04120 - - S - - - Putative amino acid metabolism
LPNMMHEL_02385 2.81e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LPNMMHEL_02386 1.95e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LPNMMHEL_02387 2.45e-40 - - - - - - - -
LPNMMHEL_02388 1.83e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LPNMMHEL_02389 8.03e-151 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LPNMMHEL_02390 7.29e-270 yaaN - - P - - - Toxic anion resistance protein (TelA)
LPNMMHEL_02391 0.0 ydiC1 - - EGP - - - Major Facilitator
LPNMMHEL_02392 5.93e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LPNMMHEL_02393 4.62e-48 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LPNMMHEL_02394 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LPNMMHEL_02395 8.49e-120 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA protein
LPNMMHEL_02396 3.98e-184 ylmH - - S - - - S4 domain protein
LPNMMHEL_02397 5.58e-60 ylmG - - S ko:K02221 - ko00000,ko02044 integral membrane protein
LPNMMHEL_02398 2.95e-101 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LPNMMHEL_02399 6.55e-291 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LPNMMHEL_02400 1.44e-311 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LPNMMHEL_02401 2.06e-200 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LPNMMHEL_02402 4e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LPNMMHEL_02403 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LPNMMHEL_02404 5.4e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LPNMMHEL_02405 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LPNMMHEL_02406 2.65e-67 ftsL - - D - - - cell division protein FtsL
LPNMMHEL_02407 2.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LPNMMHEL_02408 1.61e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LPNMMHEL_02409 7.11e-60 - - - - - - - -
LPNMMHEL_02410 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPNMMHEL_02411 2.71e-192 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LPNMMHEL_02412 9.43e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
LPNMMHEL_02413 4.79e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LPNMMHEL_02414 8.63e-182 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LPNMMHEL_02415 2.69e-148 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LPNMMHEL_02416 8.66e-113 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
LPNMMHEL_02417 1.88e-191 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LPNMMHEL_02418 4.82e-229 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
LPNMMHEL_02419 3.26e-151 radC - - L ko:K03630 - ko00000 DNA repair protein
LPNMMHEL_02420 1.34e-146 - - - S - - - Haloacid dehalogenase-like hydrolase
LPNMMHEL_02421 5.15e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LPNMMHEL_02422 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LPNMMHEL_02423 1.24e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LPNMMHEL_02424 4.95e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPNMMHEL_02425 5.01e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LPNMMHEL_02426 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LPNMMHEL_02427 7.1e-111 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LPNMMHEL_02428 5.31e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LPNMMHEL_02429 3.12e-90 - - - K - - - Cro/C1-type HTH DNA-binding domain
LPNMMHEL_02430 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
LPNMMHEL_02432 1.2e-214 - - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNMMHEL_02433 0.0 - - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
LPNMMHEL_02434 1.19e-164 - - - S - - - DJ-1/PfpI family
LPNMMHEL_02435 2.48e-69 - - - K - - - Transcriptional
LPNMMHEL_02436 3.73e-49 - - - - - - - -
LPNMMHEL_02437 0.0 - - - V - - - ABC transporter transmembrane region
LPNMMHEL_02438 3.71e-274 - - - V ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter transmembrane region
LPNMMHEL_02440 0.000177 - - - G - - - Belongs to the peptidase S8 family
LPNMMHEL_02441 2.25e-64 - - - S - - - Protein of unknown function (DUF1093)
LPNMMHEL_02445 1.35e-73 - - - L - - - Initiator Replication protein
LPNMMHEL_02448 1.9e-62 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LPNMMHEL_02449 1.55e-307 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
LPNMMHEL_02450 9.15e-34 - - - - - - - -
LPNMMHEL_02452 0.0 - - - S - - - Putative threonine/serine exporter
LPNMMHEL_02453 7.28e-41 spiA - - K - - - TRANSCRIPTIONal
LPNMMHEL_02454 7.46e-59 - - - S - - - Enterocin A Immunity
LPNMMHEL_02455 6.69e-61 - - - S - - - Enterocin A Immunity
LPNMMHEL_02456 2.99e-176 - - - - - - - -
LPNMMHEL_02457 6.77e-81 - - - - - - - -
LPNMMHEL_02458 2.05e-72 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LPNMMHEL_02459 2.1e-45 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LPNMMHEL_02460 1.52e-192 - - - M ko:K19510 - ko00000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LPNMMHEL_02461 4.33e-123 - - - M ko:K19504 - ko00000 SIS domain
LPNMMHEL_02462 1.52e-161 - - - G ko:K19509 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
LPNMMHEL_02463 5.85e-140 - - - G ko:K19508 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LPNMMHEL_02464 2.41e-70 - - - G ko:K19507 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LPNMMHEL_02465 2.11e-54 - - - K - - - GntR family
LPNMMHEL_02466 5.43e-24 dasR - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LPNMMHEL_02467 4.18e-151 epsG - - M - - - Glycosyltransferase like family 2
LPNMMHEL_02468 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPNMMHEL_02469 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
LPNMMHEL_02470 1.34e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LPNMMHEL_02471 1.04e-144 ung2 - - L - - - Uracil-DNA glycosylase
LPNMMHEL_02472 1.86e-232 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
LPNMMHEL_02473 1.16e-159 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_02474 1.23e-179 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
LPNMMHEL_02475 1.1e-182 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
LPNMMHEL_02476 1.04e-191 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
LPNMMHEL_02477 1.61e-273 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
LPNMMHEL_02478 2.51e-98 - - - S - - - Threonine/Serine exporter, ThrE
LPNMMHEL_02479 2.2e-176 - - - S - - - Putative threonine/serine exporter
LPNMMHEL_02480 3.02e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LPNMMHEL_02481 3.82e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LPNMMHEL_02482 0.0 - - - K - - - Mga helix-turn-helix domain
LPNMMHEL_02483 0.0 - - - K - - - Mga helix-turn-helix domain
LPNMMHEL_02484 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
LPNMMHEL_02485 6.99e-314 - - - S - - - O-antigen ligase like membrane protein
LPNMMHEL_02486 6.41e-196 - - - S - - - Glycosyl transferase family 2
LPNMMHEL_02487 7.26e-163 welB - - S - - - Glycosyltransferase like family 2
LPNMMHEL_02488 1.35e-204 - - - S - - - Glycosyltransferase like family 2
LPNMMHEL_02489 2.72e-190 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
LPNMMHEL_02490 4.98e-282 - - - M - - - Glycosyl hydrolases family 25
LPNMMHEL_02492 1.08e-120 - - - KL - - - SNF2 family N-terminal domain
LPNMMHEL_02494 6.95e-93 - - - D ko:K19171 - ko00000,ko02048 AAA domain
LPNMMHEL_02496 3.07e-13 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LPNMMHEL_02497 4.77e-89 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LPNMMHEL_02498 2.29e-96 tnpR - - L - - - Resolvase, N terminal domain
LPNMMHEL_02499 4.44e-273 - - - G - - - Transporter, major facilitator family protein
LPNMMHEL_02500 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LPNMMHEL_02501 4.9e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LPNMMHEL_02502 3.41e-68 yuxO - - Q - - - Thioesterase superfamily
LPNMMHEL_02503 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
LPNMMHEL_02504 3.03e-231 - - - S - - - Protein of unknown function (DUF2785)
LPNMMHEL_02505 9.85e-88 - - - S - - - Protein of unknown function (DUF1694)
LPNMMHEL_02506 4.73e-31 - - - - - - - -
LPNMMHEL_02507 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
LPNMMHEL_02508 4.94e-103 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
LPNMMHEL_02509 1.34e-277 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LPNMMHEL_02510 4.72e-244 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
LPNMMHEL_02511 4.15e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
LPNMMHEL_02512 1.31e-149 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LPNMMHEL_02513 2.43e-242 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LPNMMHEL_02514 8.04e-192 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LPNMMHEL_02515 2.67e-186 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LPNMMHEL_02516 3.19e-284 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LPNMMHEL_02517 4.19e-65 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
LPNMMHEL_02518 8.17e-285 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LPNMMHEL_02519 8.37e-42 - - - S - - - Protein of unknown function (DUF2969)
LPNMMHEL_02520 1.14e-72 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LPNMMHEL_02521 1.37e-26 - - - S - - - DNA-directed RNA polymerase subunit beta
LPNMMHEL_02522 4.12e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
LPNMMHEL_02523 8.38e-42 - - - S - - - Protein of unknown function (DUF1146)
LPNMMHEL_02524 1.88e-91 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LPNMMHEL_02525 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LPNMMHEL_02526 1.92e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LPNMMHEL_02527 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LPNMMHEL_02528 3.93e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPNMMHEL_02529 3.59e-80 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LPNMMHEL_02530 2.57e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPNMMHEL_02531 1.23e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LPNMMHEL_02532 3.05e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LPNMMHEL_02533 1.57e-298 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LPNMMHEL_02534 1.4e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LPNMMHEL_02535 6.65e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LPNMMHEL_02536 8.62e-252 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LPNMMHEL_02537 7.61e-144 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LPNMMHEL_02538 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
LPNMMHEL_02539 1.07e-250 ampC - - V - - - Beta-lactamase
LPNMMHEL_02540 9.19e-209 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
LPNMMHEL_02541 1.24e-179 - - - S - - - NADPH-dependent FMN reductase
LPNMMHEL_02542 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
LPNMMHEL_02543 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_02544 6.41e-155 - - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_02545 4.1e-163 pgm7 - - G - - - Phosphoglycerate mutase family
LPNMMHEL_02548 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LPNMMHEL_02549 4.36e-136 - - - S - - - Protein of unknown function (DUF1211)
LPNMMHEL_02550 6.01e-269 yttB - - EGP - - - Major Facilitator
LPNMMHEL_02551 1.53e-19 - - - - - - - -
LPNMMHEL_02552 6.05e-103 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
LPNMMHEL_02554 5.68e-110 guaD - - FJ - - - MafB19-like deaminase
LPNMMHEL_02555 2.56e-219 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
LPNMMHEL_02556 2.27e-293 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferases group 1
LPNMMHEL_02557 4.8e-104 - - - S - - - Pfam Transposase IS66
LPNMMHEL_02558 6.61e-195 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
LPNMMHEL_02560 1.18e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
LPNMMHEL_02561 5.22e-63 - - - S - - - Domain of unknown function DUF1829
LPNMMHEL_02562 6.02e-85 - - - S - - - Domain of unknown function DUF1829
LPNMMHEL_02563 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LPNMMHEL_02564 4.66e-196 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
LPNMMHEL_02565 2.63e-142 vanZ - - V - - - VanZ like family
LPNMMHEL_02566 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LPNMMHEL_02567 1.05e-137 - - - - - - - -
LPNMMHEL_02568 7.65e-136 - - - - - - - -
LPNMMHEL_02569 9.74e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LPNMMHEL_02570 3.86e-260 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LPNMMHEL_02571 6.23e-303 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
LPNMMHEL_02572 5.35e-133 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LPNMMHEL_02573 1.45e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
LPNMMHEL_02574 1.38e-108 yvbK - - K - - - GNAT family
LPNMMHEL_02575 6.22e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LPNMMHEL_02576 1.71e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
LPNMMHEL_02577 5.17e-134 - - - - - - - -
LPNMMHEL_02578 3.35e-217 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
LPNMMHEL_02579 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
LPNMMHEL_02580 0.0 - - - S - - - Bacterial membrane protein YfhO
LPNMMHEL_02581 2.49e-191 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LPNMMHEL_02582 0.0 bglH - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNMMHEL_02583 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNMMHEL_02584 3.11e-164 - - - N - - - domain, Protein
LPNMMHEL_02585 1.04e-72 - - - N - - - domain, Protein
LPNMMHEL_02587 4.7e-146 - - - L - - - Transposase, IS116 IS110 IS902 family
LPNMMHEL_02588 7.69e-150 - - - S - - - WxL domain surface cell wall-binding
LPNMMHEL_02589 6.03e-198 - - - S - - - Cell surface protein
LPNMMHEL_02590 5.11e-58 - - - - - - - -
LPNMMHEL_02591 1.33e-249 - - - S - - - Leucine-rich repeat (LRR) protein
LPNMMHEL_02592 6.59e-70 - - - S - - - WxL domain surface cell wall-binding
LPNMMHEL_02593 9.04e-48 lacC 2.7.1.144 - G ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LPNMMHEL_02594 1.28e-76 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
LPNMMHEL_02595 1.36e-38 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPNMMHEL_02597 2.82e-233 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 iic component
LPNMMHEL_02599 2.19e-122 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
LPNMMHEL_02600 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LPNMMHEL_02601 8.16e-43 - - - - - - - -
LPNMMHEL_02602 1.17e-156 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_02603 1.36e-93 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LPNMMHEL_02604 7.05e-195 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LPNMMHEL_02605 1.15e-185 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LPNMMHEL_02606 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
LPNMMHEL_02607 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNMMHEL_02608 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LPNMMHEL_02609 7.4e-165 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LPNMMHEL_02611 2.25e-131 tnpR - - L - - - Resolvase, N terminal domain
LPNMMHEL_02612 3.3e-315 xylP - - G - - - MFS/sugar transport protein
LPNMMHEL_02613 7.69e-134 - - - - - - - -
LPNMMHEL_02614 2.56e-46 - - - - - - - -
LPNMMHEL_02615 2.57e-124 yhfA - - S - - - HAD hydrolase, family IA, variant 3
LPNMMHEL_02616 6.35e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNMMHEL_02617 2.86e-108 uspA - - T - - - universal stress protein
LPNMMHEL_02618 1.65e-52 - - - - - - - -
LPNMMHEL_02620 5.56e-305 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LPNMMHEL_02626 5.16e-210 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LPNMMHEL_02627 2.73e-140 - - - S - - - NADPH-dependent FMN reductase
LPNMMHEL_02628 2.87e-307 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
LPNMMHEL_02629 1.98e-38 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LPNMMHEL_02630 3.42e-50 - - - L - - - Transposase DDE domain
LPNMMHEL_02632 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LPNMMHEL_02633 4.17e-55 - - - - - - - -
LPNMMHEL_02635 1.33e-166 - - - S - - - Protein of unknown function (DUF975)
LPNMMHEL_02636 5.96e-53 - - - S - - - Iron-sulphur cluster biosynthesis
LPNMMHEL_02637 1.4e-69 - - - - - - - -
LPNMMHEL_02638 8.68e-106 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
LPNMMHEL_02639 0.0 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
LPNMMHEL_02640 7.76e-186 - - - S - - - AAA ATPase domain
LPNMMHEL_02641 1.08e-212 - - - G - - - Phosphotransferase enzyme family
LPNMMHEL_02642 1.09e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_02643 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_02644 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNMMHEL_02645 9.37e-129 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LPNMMHEL_02646 2.22e-137 - - - S ko:K06384 - ko00000 Stage II sporulation protein M
LPNMMHEL_02647 3.67e-182 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
LPNMMHEL_02648 8.74e-235 - - - S - - - Protein of unknown function DUF58
LPNMMHEL_02649 0.0 yebA - - E - - - Transglutaminase/protease-like homologues
LPNMMHEL_02650 2.11e-273 - - - M - - - Glycosyl transferases group 1
LPNMMHEL_02651 1.34e-126 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LPNMMHEL_02652 1.75e-185 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LPNMMHEL_02653 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
LPNMMHEL_02654 8.26e-147 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
LPNMMHEL_02655 1.49e-61 yjdF3 - - S - - - Protein of unknown function (DUF2992)
LPNMMHEL_02656 3.65e-272 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
LPNMMHEL_02657 5.39e-292 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 2-hydroxycarboxylate transporter family
LPNMMHEL_02658 0.0 dpiB 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
LPNMMHEL_02659 6.07e-155 malR - - KT ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
LPNMMHEL_02660 2.21e-194 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
LPNMMHEL_02661 1.3e-115 M1-431 - - S - - - Protein of unknown function (DUF1706)
LPNMMHEL_02662 6.42e-86 - - - - - - - -
LPNMMHEL_02663 1.58e-284 yagE - - E - - - Amino acid permease
LPNMMHEL_02664 2.36e-217 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LPNMMHEL_02665 3.5e-88 - - - V - - - Domain of unknown function (DUF3883)
LPNMMHEL_02669 1.11e-283 sip - - L - - - Belongs to the 'phage' integrase family
LPNMMHEL_02670 2.32e-06 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LPNMMHEL_02671 2.26e-50 - - - - - - - -
LPNMMHEL_02672 1.19e-41 - - - - - - - -
LPNMMHEL_02673 3.66e-18 - - - - - - - -
LPNMMHEL_02674 3.61e-34 - - - - - - - -
LPNMMHEL_02675 1.09e-47 - - - - - - - -
LPNMMHEL_02676 1.78e-11 - - - - - - - -
LPNMMHEL_02677 5.66e-171 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
LPNMMHEL_02678 3.34e-173 - - - S ko:K06919 - ko00000 D5 N terminal like
LPNMMHEL_02680 8.05e-106 terS - - L - - - Phage terminase, small subunit
LPNMMHEL_02681 0.0 terL - - S - - - overlaps another CDS with the same product name
LPNMMHEL_02682 6.27e-31 - - - - - - - -
LPNMMHEL_02683 1.07e-281 - - - S - - - Phage portal protein
LPNMMHEL_02684 0.0 - - - S ko:K06904 - ko00000 Phage capsid family
LPNMMHEL_02685 2.28e-63 - - - S - - - Phage gp6-like head-tail connector protein
LPNMMHEL_02686 6.83e-18 - - - S - - - Phage head-tail joining protein
LPNMMHEL_02687 2.3e-23 - - - - - - - -
LPNMMHEL_02688 1.4e-35 ytgB - - S - - - Transglycosylase associated protein
LPNMMHEL_02690 1.87e-217 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPNMMHEL_02691 2.32e-233 - - - D ko:K06889 - ko00000 Alpha beta
LPNMMHEL_02692 2.16e-238 lipA - - I - - - Carboxylesterase family
LPNMMHEL_02693 1.68e-275 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
LPNMMHEL_02694 9.2e-101 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNMMHEL_02695 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
LPNMMHEL_02696 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LPNMMHEL_02697 2.09e-169 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LPNMMHEL_02698 2.23e-191 - - - S - - - haloacid dehalogenase-like hydrolase
LPNMMHEL_02699 5.93e-59 - - - - - - - -
LPNMMHEL_02700 6.72e-19 - - - - - - - -
LPNMMHEL_02701 8.73e-238 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPNMMHEL_02702 2.9e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LPNMMHEL_02703 2.95e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
LPNMMHEL_02704 6.51e-51 - - - M - - - Leucine rich repeats (6 copies)
LPNMMHEL_02705 0.0 - - - M - - - Leucine rich repeats (6 copies)
LPNMMHEL_02706 1.86e-84 ypjH - - C ko:K08317 - ko00000,ko01000 dehydrogenase
LPNMMHEL_02708 4.92e-65 - - - - - - - -
LPNMMHEL_02709 4.35e-197 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
LPNMMHEL_02710 9.71e-127 - - - K - - - transcriptional regulator
LPNMMHEL_02711 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNMMHEL_02712 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LPNMMHEL_02713 1.87e-191 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
LPNMMHEL_02717 1.06e-165 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
LPNMMHEL_02719 0.0 repE - - K - - - Primase C terminal 1 (PriCT-1)
LPNMMHEL_02720 1.68e-177 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LPNMMHEL_02721 1.44e-170 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
LPNMMHEL_02722 1.4e-217 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPNMMHEL_02723 3.95e-102 - - - L - - - Psort location Cytoplasmic, score
LPNMMHEL_02724 2.38e-150 - - - S - - - CRISPR-associated protein (Cas_Csn2)
LPNMMHEL_02725 1.65e-61 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LPNMMHEL_02726 5.38e-161 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LPNMMHEL_02727 4.47e-25 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LPNMMHEL_02728 7.63e-134 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LPNMMHEL_02729 1.98e-50 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
LPNMMHEL_02730 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
LPNMMHEL_02731 1.28e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
LPNMMHEL_02732 1.79e-80 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LPNMMHEL_02733 3.12e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LPNMMHEL_02734 8.06e-232 - - - M - - - Glycosyl hydrolases family 25
LPNMMHEL_02735 2.26e-212 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LPNMMHEL_02736 1.28e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LPNMMHEL_02737 3.38e-128 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
LPNMMHEL_02738 4.49e-74 - - - L - - - Transposase DDE domain
LPNMMHEL_02739 2.24e-71 - - - L - - - Transposase DDE domain
LPNMMHEL_02740 7.48e-49 mntH - - P ko:K03322 - ko00000,ko02000 Natural resistance-associated macrophage protein
LPNMMHEL_02741 2.33e-209 - - - P - - - CorA-like Mg2+ transporter protein
LPNMMHEL_02742 3.34e-117 - - - L ko:K07497 - ko00000 hmm pf00665
LPNMMHEL_02743 4.6e-89 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
LPNMMHEL_02744 8.12e-117 - - - - - - - -
LPNMMHEL_02745 3.83e-61 - - - L - - - BRCA1 C Terminus (BRCT) domain
LPNMMHEL_02746 8.05e-149 - - - L - - - Resolvase, N terminal domain
LPNMMHEL_02748 5.19e-90 - - - S - - - COG NOG38524 non supervised orthologous group
LPNMMHEL_02749 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPNMMHEL_02750 5.23e-36 - - - - - - - -
LPNMMHEL_02751 1.41e-209 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LPNMMHEL_02752 2.1e-27 - - - - - - - -
LPNMMHEL_02756 4.37e-153 - - - - - - - -
LPNMMHEL_02761 3.56e-68 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LPNMMHEL_02762 7.25e-88 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LPNMMHEL_02763 6.72e-60 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LPNMMHEL_02764 4.25e-28 - - - S - - - RelE toxin of RelE / RelB toxin-antitoxin system
LPNMMHEL_02766 8.7e-280 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LPNMMHEL_02767 8.76e-282 - - - P - - - Cation transporter/ATPase, N-terminus
LPNMMHEL_02768 1.99e-212 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
LPNMMHEL_02769 4.28e-178 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LPNMMHEL_02770 1e-173 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNMMHEL_02771 3.27e-187 ptxC - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNMMHEL_02773 2.02e-71 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
LPNMMHEL_02774 3.79e-112 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
LPNMMHEL_02775 0.0 - 6.2.1.48 - IQ ko:K02182 - ko00000,ko01000 AMP-binding enzyme C-terminal domain
LPNMMHEL_02776 1.1e-298 - - - I - - - Acyltransferase family
LPNMMHEL_02777 1.17e-154 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_02778 1.62e-189 ssuC - - U ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNMMHEL_02779 3.91e-24 - - - S - - - Protein of unknown function (DUF2785)
LPNMMHEL_02780 3.13e-106 - - - - - - - -
LPNMMHEL_02781 5.94e-71 - - - - - - - -
LPNMMHEL_02782 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LPNMMHEL_02783 2.98e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LPNMMHEL_02784 1.06e-133 - - - K - - - Bacterial regulatory proteins, tetR family
LPNMMHEL_02785 2.05e-235 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
LPNMMHEL_02786 1.05e-163 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNMMHEL_02787 6.11e-44 - - - - - - - -
LPNMMHEL_02788 8.93e-114 tipA - - K - - - TipAS antibiotic-recognition domain
LPNMMHEL_02789 1.8e-30 tipA - - K - - - TipAS antibiotic-recognition domain
LPNMMHEL_02790 1.39e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LPNMMHEL_02791 3.8e-180 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPNMMHEL_02792 1.92e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPNMMHEL_02793 4.68e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPNMMHEL_02794 2.85e-141 - - - - - - - -
LPNMMHEL_02795 3.16e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LPNMMHEL_02796 1.26e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPNMMHEL_02797 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LPNMMHEL_02798 5.37e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LPNMMHEL_02799 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LPNMMHEL_02800 4.15e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LPNMMHEL_02801 1.29e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LPNMMHEL_02802 4.06e-303 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LPNMMHEL_02803 4.07e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LPNMMHEL_02804 2.6e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LPNMMHEL_02805 5.74e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LPNMMHEL_02806 1.62e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LPNMMHEL_02807 2.61e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LPNMMHEL_02808 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LPNMMHEL_02809 8.67e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LPNMMHEL_02810 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LPNMMHEL_02811 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LPNMMHEL_02812 5.93e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LPNMMHEL_02813 3.55e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LPNMMHEL_02814 2.78e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LPNMMHEL_02815 6.88e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LPNMMHEL_02816 1.29e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LPNMMHEL_02817 5.26e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LPNMMHEL_02818 7.23e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LPNMMHEL_02819 1.02e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LPNMMHEL_02820 1.98e-140 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LPNMMHEL_02821 4.01e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LPNMMHEL_02822 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LPNMMHEL_02823 3.63e-90 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
LPNMMHEL_02824 2.38e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
LPNMMHEL_02825 1.18e-255 - - - K - - - WYL domain
LPNMMHEL_02826 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LPNMMHEL_02827 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LPNMMHEL_02828 1.11e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LPNMMHEL_02829 0.0 - - - M - - - domain protein
LPNMMHEL_02830 1.81e-47 - 3.4.23.43 - - ko:K02236 - ko00000,ko00002,ko01000,ko02044 -
LPNMMHEL_02831 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPNMMHEL_02832 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPNMMHEL_02833 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LPNMMHEL_02834 6.14e-105 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)