ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GDHHKMLE_00001 3.47e-117 - - - E - - - HAD-hyrolase-like
GDHHKMLE_00002 3.8e-119 yfbM - - K - - - FR47-like protein
GDHHKMLE_00003 3.15e-173 - - - S - - - -acetyltransferase
GDHHKMLE_00004 8.82e-68 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
GDHHKMLE_00005 6.53e-174 draG - - O - - - ADP-ribosylglycohydrolase
GDHHKMLE_00006 3.78e-219 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GDHHKMLE_00007 2.52e-130 - - - S - - - endonuclease exonuclease phosphatase family protein
GDHHKMLE_00008 1.76e-237 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GDHHKMLE_00009 5.86e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_00010 1.03e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
GDHHKMLE_00011 4.22e-236 - - - M - - - Leucine rich repeats (6 copies)
GDHHKMLE_00012 5.51e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GDHHKMLE_00013 8.94e-224 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GDHHKMLE_00014 6.42e-208 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GDHHKMLE_00015 1.28e-257 - - - S - - - Calcineurin-like phosphoesterase
GDHHKMLE_00016 0.0 - - - EGP - - - Major Facilitator
GDHHKMLE_00017 8.19e-161 - - - S ko:K07090 - ko00000 membrane transporter protein
GDHHKMLE_00018 1.23e-232 - - - K - - - Helix-turn-helix XRE-family like proteins
GDHHKMLE_00019 4.73e-209 - - - S - - - Alpha beta hydrolase
GDHHKMLE_00020 2.73e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
GDHHKMLE_00021 1.53e-54 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GDHHKMLE_00022 5.66e-193 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GDHHKMLE_00023 1.56e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
GDHHKMLE_00024 7.63e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GDHHKMLE_00025 2.04e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GDHHKMLE_00028 1.34e-94 - - - L - - - Type III restriction enzyme, res subunit
GDHHKMLE_00029 4.65e-128 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
GDHHKMLE_00030 1.2e-65 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
GDHHKMLE_00031 1.24e-192 - - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GDHHKMLE_00032 1.71e-196 fbpC 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 TOBE domain
GDHHKMLE_00033 1.17e-313 sfuB - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GDHHKMLE_00034 6.94e-41 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GDHHKMLE_00035 2.96e-301 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GDHHKMLE_00036 0.0 bglH - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GDHHKMLE_00037 8.33e-190 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
GDHHKMLE_00038 8e-108 - - - - - - - -
GDHHKMLE_00039 4.04e-79 - - - S - - - MucBP domain
GDHHKMLE_00040 1.02e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
GDHHKMLE_00043 2.36e-167 - - - E - - - lipolytic protein G-D-S-L family
GDHHKMLE_00044 4.14e-91 - - - P ko:K04758 - ko00000,ko02000 FeoA
GDHHKMLE_00045 7.13e-149 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
GDHHKMLE_00046 1.96e-182 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GDHHKMLE_00047 1.95e-290 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GDHHKMLE_00048 3.57e-130 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
GDHHKMLE_00049 1.94e-137 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
GDHHKMLE_00050 6.12e-115 - - - - - - - -
GDHHKMLE_00051 4.42e-154 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GDHHKMLE_00052 4.2e-230 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GDHHKMLE_00053 4.08e-289 - - - EK - - - Aminotransferase, class I
GDHHKMLE_00054 4.39e-213 - - - K - - - LysR substrate binding domain
GDHHKMLE_00055 1.38e-117 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GDHHKMLE_00056 7.22e-197 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GDHHKMLE_00057 1.56e-161 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
GDHHKMLE_00058 7.74e-135 - - - S - - - Protein of unknown function (DUF1275)
GDHHKMLE_00059 1.99e-16 - - - - - - - -
GDHHKMLE_00060 4.04e-79 - - - - - - - -
GDHHKMLE_00061 4.82e-186 - - - S - - - hydrolase
GDHHKMLE_00062 8.52e-244 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
GDHHKMLE_00063 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
GDHHKMLE_00064 4.38e-28 - - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 ABC transporter
GDHHKMLE_00065 1.06e-90 - - - K - - - MarR family
GDHHKMLE_00066 3.47e-147 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GDHHKMLE_00068 7.74e-146 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GDHHKMLE_00069 3.77e-221 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 Voltage-dependent anion channel
GDHHKMLE_00070 1.14e-192 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
GDHHKMLE_00071 0.0 - - - L - - - DNA helicase
GDHHKMLE_00073 0.0 choS - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GDHHKMLE_00074 2.47e-224 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_00075 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
GDHHKMLE_00076 1.48e-246 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GDHHKMLE_00077 1.15e-132 lemA - - S ko:K03744 - ko00000 LemA family
GDHHKMLE_00078 5.89e-156 - - - S ko:K06872 - ko00000 TPM domain
GDHHKMLE_00079 5.58e-306 dinF - - V - - - MatE
GDHHKMLE_00080 6.5e-119 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
GDHHKMLE_00081 4.01e-196 - - - Q - - - Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
GDHHKMLE_00082 4.48e-172 ydhF - - S - - - Aldo keto reductase
GDHHKMLE_00083 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GDHHKMLE_00084 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GDHHKMLE_00085 2.57e-223 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GDHHKMLE_00086 3.25e-203 ypuA - - S - - - Protein of unknown function (DUF1002)
GDHHKMLE_00087 4.7e-50 - - - - - - - -
GDHHKMLE_00088 3.21e-125 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
GDHHKMLE_00089 5.59e-220 - - - - - - - -
GDHHKMLE_00090 6.41e-24 - - - - - - - -
GDHHKMLE_00091 5.67e-165 cobB - - K ko:K12410 - ko00000,ko01000 Sir2 family
GDHHKMLE_00092 9.14e-139 yiiE - - S - - - Protein of unknown function (DUF1211)
GDHHKMLE_00093 3.11e-218 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GDHHKMLE_00094 1.82e-117 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GDHHKMLE_00095 1.7e-195 yunF - - F - - - Protein of unknown function DUF72
GDHHKMLE_00096 4.11e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GDHHKMLE_00097 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GDHHKMLE_00098 3.51e-41 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GDHHKMLE_00099 1.66e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_00100 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
GDHHKMLE_00105 6.04e-12 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
GDHHKMLE_00106 2.1e-248 butB 1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4 - C ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
GDHHKMLE_00107 6.57e-18 - - - L - - - IrrE N-terminal-like domain
GDHHKMLE_00109 1.35e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GDHHKMLE_00110 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GDHHKMLE_00112 1.25e-83 - - - S - - - Phospholipase A2
GDHHKMLE_00113 7.95e-58 cps4G - - M - - - Glycosyltransferase Family 4
GDHHKMLE_00114 4.95e-36 - - - S - - - Glycosyltransferase like family 2
GDHHKMLE_00115 4.87e-40 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GDHHKMLE_00116 5.39e-30 - - - M - - - Glycosyl transferase 4-like domain
GDHHKMLE_00117 3.4e-15 - - - S - - - Initiator Replication protein
GDHHKMLE_00120 5.19e-37 - - - U - - - Relaxase/Mobilisation nuclease domain
GDHHKMLE_00121 5.85e-26 - - - S - - - Bacterial mobilisation protein (MobC)
GDHHKMLE_00122 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
GDHHKMLE_00123 7.26e-208 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
GDHHKMLE_00124 3.87e-80 - - - - - - - -
GDHHKMLE_00125 2.05e-72 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
GDHHKMLE_00126 2.06e-143 - - - K - - - Helix-turn-helix XRE-family like proteins
GDHHKMLE_00127 1.15e-261 - - - S - - - Protein of unknown function (DUF2974)
GDHHKMLE_00128 1.98e-50 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
GDHHKMLE_00129 0.0 copB 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
GDHHKMLE_00130 1.28e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
GDHHKMLE_00132 3.45e-82 - - - L - - - Psort location Cytoplasmic, score
GDHHKMLE_00133 0.0 traA - - L - - - MobA MobL family protein
GDHHKMLE_00134 2.51e-30 - - - - - - - -
GDHHKMLE_00135 1.06e-12 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
GDHHKMLE_00136 5.8e-29 - - - K - - - DeoR C terminal sensor domain
GDHHKMLE_00137 9.04e-35 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
GDHHKMLE_00138 9.9e-301 yagE - - E - - - Amino acid permease
GDHHKMLE_00139 9.48e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GDHHKMLE_00140 2.28e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GDHHKMLE_00141 2.29e-87 - - - - - - - -
GDHHKMLE_00142 2.61e-163 - - - - - - - -
GDHHKMLE_00143 5.08e-158 - - - S - - - Tetratricopeptide repeat
GDHHKMLE_00144 4.87e-187 - - - - - - - -
GDHHKMLE_00145 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GDHHKMLE_00146 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GDHHKMLE_00147 2.63e-82 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GDHHKMLE_00148 2.3e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GDHHKMLE_00149 4.66e-44 - - - - - - - -
GDHHKMLE_00150 5.68e-83 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
GDHHKMLE_00151 1.14e-111 queT - - S - - - QueT transporter
GDHHKMLE_00152 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
GDHHKMLE_00153 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GDHHKMLE_00154 1.98e-167 yciB - - M - - - ErfK YbiS YcfS YnhG
GDHHKMLE_00155 1.34e-154 - - - S - - - (CBS) domain
GDHHKMLE_00156 0.0 - - - S - - - Putative peptidoglycan binding domain
GDHHKMLE_00157 7.16e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GDHHKMLE_00158 4.28e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GDHHKMLE_00159 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GDHHKMLE_00160 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GDHHKMLE_00161 1.99e-53 yabO - - J - - - S4 domain protein
GDHHKMLE_00162 7.17e-87 divIC - - D ko:K05589,ko:K13052 - ko00000,ko03036 cell cycle
GDHHKMLE_00163 1.17e-105 yabR - - J ko:K07571 - ko00000 RNA binding
GDHHKMLE_00164 1.55e-309 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GDHHKMLE_00165 1.14e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GDHHKMLE_00166 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GDHHKMLE_00167 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
GDHHKMLE_00168 2.77e-249 - - - S - - - Protein of unknown function C-terminal (DUF3324)
GDHHKMLE_00169 2.83e-235 - - - S - - - Bacterial protein of unknown function (DUF916)
GDHHKMLE_00170 3.83e-202 - - - S - - - WxL domain surface cell wall-binding
GDHHKMLE_00171 2.43e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GDHHKMLE_00172 3.08e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GDHHKMLE_00173 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GDHHKMLE_00174 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GDHHKMLE_00175 8.99e-138 pncA - - Q - - - Isochorismatase family
GDHHKMLE_00176 3.28e-175 - - - F - - - NUDIX domain
GDHHKMLE_00177 1.75e-168 - - - E - - - lipolytic protein G-D-S-L family
GDHHKMLE_00178 1.43e-52 - - - K - - - Protein of unknown function (DUF4065)
GDHHKMLE_00179 9.9e-105 ccl - - S - - - QueT transporter
GDHHKMLE_00180 2.57e-160 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GDHHKMLE_00181 8.55e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
GDHHKMLE_00182 2.38e-123 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
GDHHKMLE_00183 2.85e-104 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GDHHKMLE_00184 1.47e-34 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GDHHKMLE_00185 9.11e-15 - - - - - - - -
GDHHKMLE_00186 1.56e-289 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GDHHKMLE_00187 4.56e-17 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
GDHHKMLE_00188 7.35e-228 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GDHHKMLE_00189 2.31e-295 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GDHHKMLE_00191 9.85e-11 ybbB - - S - - - Protein of unknown function (DUF1211)
GDHHKMLE_00192 2.63e-166 ybbB - - S - - - Protein of unknown function (DUF1211)
GDHHKMLE_00193 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GDHHKMLE_00194 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GDHHKMLE_00195 9.45e-261 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GDHHKMLE_00196 8.3e-123 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
GDHHKMLE_00197 0.0 ybeC - - E - - - amino acid
GDHHKMLE_00198 1.31e-216 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GDHHKMLE_00200 5.49e-206 lysR - - K - - - Transcriptional regulator
GDHHKMLE_00201 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GDHHKMLE_00202 1e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GDHHKMLE_00203 8.85e-47 - - - - - - - -
GDHHKMLE_00204 3e-221 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
GDHHKMLE_00205 6.61e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GDHHKMLE_00206 7.09e-88 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GDHHKMLE_00207 6.54e-138 ypsA - - S - - - Belongs to the UPF0398 family
GDHHKMLE_00208 5.12e-157 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GDHHKMLE_00209 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GDHHKMLE_00210 5.94e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GDHHKMLE_00211 7.61e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GDHHKMLE_00212 3.19e-146 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
GDHHKMLE_00213 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
GDHHKMLE_00214 6.64e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GDHHKMLE_00215 2.03e-111 ypmB - - S - - - Protein conserved in bacteria
GDHHKMLE_00216 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GDHHKMLE_00217 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GDHHKMLE_00218 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GDHHKMLE_00220 1.03e-212 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
GDHHKMLE_00221 3.82e-231 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GDHHKMLE_00222 1.31e-243 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GDHHKMLE_00223 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
GDHHKMLE_00224 5.38e-223 - - - - - - - -
GDHHKMLE_00225 7.48e-183 - - - - - - - -
GDHHKMLE_00226 2.32e-79 yitW - - S - - - Iron-sulfur cluster assembly protein
GDHHKMLE_00227 2.03e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GDHHKMLE_00228 2.32e-190 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GDHHKMLE_00229 1.14e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GDHHKMLE_00230 9.19e-249 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GDHHKMLE_00231 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GDHHKMLE_00232 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GDHHKMLE_00233 2.11e-219 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GDHHKMLE_00234 2.49e-54 - - - - - - - -
GDHHKMLE_00235 5.39e-64 - - - L - - - Transposase DDE domain
GDHHKMLE_00237 5.67e-87 - - - K - - - Primase C terminal 1 (PriCT-1)
GDHHKMLE_00238 2.44e-54 - - - - - - - -
GDHHKMLE_00239 1.4e-163 - - - S - - - protein conserved in bacteria
GDHHKMLE_00240 1.35e-38 - - - - - - - -
GDHHKMLE_00241 2.83e-58 - - - L - - - Addiction module antitoxin, RelB DinJ family
GDHHKMLE_00242 1.61e-123 repA - - S - - - Replication initiator protein A
GDHHKMLE_00243 5.3e-193 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GDHHKMLE_00244 1.83e-218 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
GDHHKMLE_00245 3.52e-33 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GDHHKMLE_00246 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GDHHKMLE_00247 6.21e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GDHHKMLE_00248 1.49e-107 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GDHHKMLE_00249 2.02e-87 rdrB - - K ko:K02444,ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
GDHHKMLE_00251 5.93e-12 - - - - - - - -
GDHHKMLE_00252 1.28e-132 - - - - - - - -
GDHHKMLE_00253 3.79e-293 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
GDHHKMLE_00254 2.87e-21 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GDHHKMLE_00259 1.07e-51 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
GDHHKMLE_00261 8.76e-28 - - - - - - - -
GDHHKMLE_00262 3.05e-09 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
GDHHKMLE_00265 8.53e-222 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 cysteine-type peptidase activity
GDHHKMLE_00267 4.95e-110 repA - - S - - - Replication initiator protein A
GDHHKMLE_00268 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
GDHHKMLE_00269 6.42e-47 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GDHHKMLE_00270 1.38e-299 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GDHHKMLE_00273 0.0 pip - - V ko:K01421 - ko00000 domain protein
GDHHKMLE_00274 0.0 - - - GK - - - helix_turn_helix, arabinose operon control protein
GDHHKMLE_00275 4.56e-242 - - - G - - - Major Facilitator Superfamily
GDHHKMLE_00276 0.0 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
GDHHKMLE_00277 5.25e-199 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GDHHKMLE_00278 4.15e-173 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
GDHHKMLE_00279 2.24e-58 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
GDHHKMLE_00280 3.52e-105 - - - - - - - -
GDHHKMLE_00281 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GDHHKMLE_00282 4.2e-22 - - - - - - - -
GDHHKMLE_00283 1.6e-127 - - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_00284 2.1e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
GDHHKMLE_00285 1.42e-133 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
GDHHKMLE_00286 2.09e-242 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
GDHHKMLE_00287 4.13e-99 - - - O - - - OsmC-like protein
GDHHKMLE_00288 0.0 - - - L - - - Exonuclease
GDHHKMLE_00289 4.23e-64 yczG - - K - - - Helix-turn-helix domain
GDHHKMLE_00290 1.99e-65 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
GDHHKMLE_00291 4.55e-135 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
GDHHKMLE_00292 8.57e-25 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
GDHHKMLE_00293 4.02e-138 ydfF - - K - - - Transcriptional
GDHHKMLE_00294 2.66e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GDHHKMLE_00295 5.36e-215 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GDHHKMLE_00296 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GDHHKMLE_00297 2.34e-244 pbpE - - V - - - Beta-lactamase
GDHHKMLE_00298 7.69e-191 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GDHHKMLE_00299 1.06e-183 - - - H - - - Protein of unknown function (DUF1698)
GDHHKMLE_00300 5.24e-180 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GDHHKMLE_00301 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase, catalytic domain
GDHHKMLE_00302 8.05e-281 - - - S ko:K07045 - ko00000 Amidohydrolase
GDHHKMLE_00303 0.0 - - - E - - - Amino acid permease
GDHHKMLE_00304 1.68e-98 - - - K - - - helix_turn_helix, mercury resistance
GDHHKMLE_00305 6.47e-209 - - - S - - - reductase
GDHHKMLE_00306 2.05e-263 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
GDHHKMLE_00307 4.4e-75 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
GDHHKMLE_00308 1.26e-132 tnpR1 - - L - - - Resolvase, N terminal domain
GDHHKMLE_00309 7.78e-46 yvcC - - M - - - Cna protein B-type domain
GDHHKMLE_00310 1.8e-164 epsB - - M - - - biosynthesis protein
GDHHKMLE_00311 8.88e-138 ywqD - - D - - - Capsular exopolysaccharide family
GDHHKMLE_00312 1.72e-140 - - - S - - - Flavodoxin-like fold
GDHHKMLE_00313 6.76e-125 - - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_00337 5.36e-49 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GDHHKMLE_00338 1.5e-35 - - - - - - - -
GDHHKMLE_00339 9.17e-111 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GDHHKMLE_00340 8.04e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GDHHKMLE_00341 5.5e-192 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GDHHKMLE_00342 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
GDHHKMLE_00343 1.32e-77 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
GDHHKMLE_00345 1.1e-59 - - - S - - - Initiator Replication protein
GDHHKMLE_00346 1.15e-208 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GDHHKMLE_00347 2.65e-67 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
GDHHKMLE_00348 2.35e-90 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GDHHKMLE_00349 1.36e-285 inlJ - - M - - - MucBP domain
GDHHKMLE_00350 5.31e-82 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
GDHHKMLE_00351 3.76e-224 - - - S - - - Membrane
GDHHKMLE_00352 2.26e-146 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
GDHHKMLE_00353 7.02e-182 - - - K - - - SIS domain
GDHHKMLE_00354 1.18e-149 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GDHHKMLE_00355 8.13e-238 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GDHHKMLE_00356 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GDHHKMLE_00358 2.97e-136 - - - - - - - -
GDHHKMLE_00359 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
GDHHKMLE_00360 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GDHHKMLE_00361 4.83e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GDHHKMLE_00362 3.14e-181 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GDHHKMLE_00363 5.04e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
GDHHKMLE_00365 5.78e-246 XK27_00915 - - C - - - Luciferase-like monooxygenase
GDHHKMLE_00366 6.6e-158 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 Rossmann-like domain
GDHHKMLE_00369 8.65e-228 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GDHHKMLE_00370 4.18e-127 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
GDHHKMLE_00371 2.76e-104 - - - S - - - NusG domain II
GDHHKMLE_00372 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GDHHKMLE_00373 6.86e-187 cad - - S ko:K20379 ko02024,map02024 ko00000,ko00001 FMN_bind
GDHHKMLE_00374 6.32e-252 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GDHHKMLE_00375 2.85e-215 menA 2.5.1.74 - M ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
GDHHKMLE_00376 4.58e-220 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GDHHKMLE_00377 2.09e-30 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GDHHKMLE_00378 2.29e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GDHHKMLE_00379 8.15e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GDHHKMLE_00380 4.4e-101 - - - F - - - Nucleoside 2-deoxyribosyltransferase
GDHHKMLE_00381 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
GDHHKMLE_00382 4.31e-83 - - - S - - - Domain of unknown function (DUF4430)
GDHHKMLE_00383 1.31e-123 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
GDHHKMLE_00384 1.4e-116 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
GDHHKMLE_00385 3.48e-86 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
GDHHKMLE_00386 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
GDHHKMLE_00387 1.86e-145 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GDHHKMLE_00388 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GDHHKMLE_00389 6.87e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GDHHKMLE_00390 1.89e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GDHHKMLE_00391 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GDHHKMLE_00392 1.07e-136 - - - S - - - EcsC protein family
GDHHKMLE_00393 3.31e-137 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
GDHHKMLE_00394 1.4e-26 - - - S - - - Family of unknown function (DUF5388)
GDHHKMLE_00395 1.43e-29 - - - - - - - -
GDHHKMLE_00398 3.38e-166 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
GDHHKMLE_00399 1.24e-39 - - - - - - - -
GDHHKMLE_00400 1.45e-46 - - - - - - - -
GDHHKMLE_00401 1.27e-221 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GDHHKMLE_00402 5.83e-73 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GDHHKMLE_00403 1.34e-55 yhgE - - V ko:K01421 - ko00000 domain protein
GDHHKMLE_00404 1.56e-67 yhgE - - V ko:K01421 - ko00000 domain protein
GDHHKMLE_00405 1.97e-212 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
GDHHKMLE_00407 1.42e-109 - - - K - - - SIR2-like domain
GDHHKMLE_00408 6.02e-143 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GDHHKMLE_00409 2.27e-216 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GDHHKMLE_00410 3.25e-181 - - - - - - - -
GDHHKMLE_00411 7.63e-275 - - - S - - - Membrane
GDHHKMLE_00412 1.12e-82 - - - S - - - Protein of unknown function (DUF1093)
GDHHKMLE_00413 8.79e-64 - - - - - - - -
GDHHKMLE_00414 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GDHHKMLE_00415 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GDHHKMLE_00416 2.5e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
GDHHKMLE_00417 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GDHHKMLE_00418 8.2e-304 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
GDHHKMLE_00419 1.21e-241 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GDHHKMLE_00420 6.98e-53 - - - - - - - -
GDHHKMLE_00421 1.22e-112 - - - - - - - -
GDHHKMLE_00422 2.74e-33 - - - - - - - -
GDHHKMLE_00423 1.72e-213 - - - EG - - - EamA-like transporter family
GDHHKMLE_00424 3.45e-144 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GDHHKMLE_00425 9.59e-101 usp5 - - T - - - universal stress protein
GDHHKMLE_00426 3.25e-74 - - - K - - - Helix-turn-helix domain
GDHHKMLE_00427 1.29e-186 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GDHHKMLE_00428 6.69e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
GDHHKMLE_00429 1.54e-84 - - - - - - - -
GDHHKMLE_00430 7.09e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
GDHHKMLE_00431 5.77e-93 adhR - - K - - - helix_turn_helix, mercury resistance
GDHHKMLE_00432 1.44e-104 - - - C - - - Flavodoxin
GDHHKMLE_00433 1.81e-251 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GDHHKMLE_00434 6.48e-147 - - - GM - - - NmrA-like family
GDHHKMLE_00436 5.62e-132 - - - Q - - - methyltransferase
GDHHKMLE_00437 7.76e-143 - - - T - - - Sh3 type 3 domain protein
GDHHKMLE_00438 6.72e-152 - - - F - - - glutamine amidotransferase
GDHHKMLE_00439 1.05e-173 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
GDHHKMLE_00440 0.0 yhdP - - S - - - Transporter associated domain
GDHHKMLE_00441 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GDHHKMLE_00442 9.76e-79 - - - S - - - Domain of unknown function (DUF4811)
GDHHKMLE_00443 1.95e-127 maf - - D ko:K06287 - ko00000 nucleoside-triphosphate diphosphatase activity
GDHHKMLE_00444 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GDHHKMLE_00445 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GDHHKMLE_00446 0.0 ydaO - - E - - - amino acid
GDHHKMLE_00447 5.32e-75 - - - S - - - Domain of unknown function (DUF1827)
GDHHKMLE_00448 1.76e-168 - - - L - - - Transposase, IS116 IS110 IS902 family
GDHHKMLE_00449 5.81e-181 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_00450 5.43e-22 - - - - - - - -
GDHHKMLE_00451 1.43e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GDHHKMLE_00452 1.42e-138 - - - L - - - Transposase DDE domain
GDHHKMLE_00453 5.83e-161 - - - L - - - Transposase DDE domain
GDHHKMLE_00454 0.0 - - - L - - - Transposase DDE domain
GDHHKMLE_00455 0.0 - - - L - - - Transposase DDE domain
GDHHKMLE_00456 5.39e-70 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
GDHHKMLE_00458 1.42e-31 - - - - - - - -
GDHHKMLE_00459 5.45e-26 - - - - - - - -
GDHHKMLE_00460 2.92e-42 - - - - - - - -
GDHHKMLE_00462 3.68e-77 yafQ - - S ko:K19157 - ko00000,ko01000,ko02048 endonuclease activity
GDHHKMLE_00463 1.15e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
GDHHKMLE_00464 6.91e-118 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
GDHHKMLE_00465 1.96e-24 - - - S - - - Family of unknown function (DUF5388)
GDHHKMLE_00466 7.58e-99 - - - - - - - -
GDHHKMLE_00467 3.52e-79 - - - - - - - -
GDHHKMLE_00470 3.14e-254 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
GDHHKMLE_00472 1.15e-203 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GDHHKMLE_00473 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GDHHKMLE_00474 7.1e-224 ccpB - - K - - - lacI family
GDHHKMLE_00475 1.1e-57 - - - - - - - -
GDHHKMLE_00476 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GDHHKMLE_00477 1.12e-137 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
GDHHKMLE_00478 9.05e-67 - - - - - - - -
GDHHKMLE_00479 4.38e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GDHHKMLE_00480 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GDHHKMLE_00481 7e-49 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GDHHKMLE_00482 2.53e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GDHHKMLE_00483 2.95e-46 - - - S - - - Protein of unknown function (DUF2508)
GDHHKMLE_00484 1.77e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GDHHKMLE_00485 1.14e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
GDHHKMLE_00486 4.59e-223 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GDHHKMLE_00487 7.92e-76 yabA - - L - - - Involved in initiation control of chromosome replication
GDHHKMLE_00488 6.07e-192 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GDHHKMLE_00489 3.86e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GDHHKMLE_00490 2.05e-230 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
GDHHKMLE_00491 2.42e-117 - - - T - - - ECF transporter, substrate-specific component
GDHHKMLE_00492 2.81e-94 - - - - - - - -
GDHHKMLE_00493 3.82e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
GDHHKMLE_00494 8.44e-130 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
GDHHKMLE_00495 5.99e-243 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GDHHKMLE_00496 3.12e-68 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GDHHKMLE_00497 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
GDHHKMLE_00498 1.1e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GDHHKMLE_00499 4.97e-81 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
GDHHKMLE_00500 4e-202 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_00501 6.65e-236 - - - - - - - -
GDHHKMLE_00502 2.89e-251 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GDHHKMLE_00503 6.1e-143 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
GDHHKMLE_00504 1.7e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GDHHKMLE_00505 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GDHHKMLE_00508 4.69e-64 - - - M - - - transferase activity, transferring glycosyl groups
GDHHKMLE_00509 1.63e-06 - - - - - - - -
GDHHKMLE_00510 8.71e-59 - - - L ko:K07483 - ko00000 4.5 Transposon and IS
GDHHKMLE_00511 7.23e-200 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
GDHHKMLE_00512 9.51e-173 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GDHHKMLE_00513 7.01e-67 rdrB - - K ko:K02444,ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
GDHHKMLE_00514 3.48e-131 - - - J - - - Methyltransferase domain
GDHHKMLE_00515 2.25e-64 - - - S - - - Protein of unknown function (DUF1093)
GDHHKMLE_00516 1.01e-51 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
GDHHKMLE_00517 2.89e-117 ydhK - - M - - - Protein of unknown function (DUF1541)
GDHHKMLE_00518 1.64e-128 - - - - - - - -
GDHHKMLE_00519 1.56e-49 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
GDHHKMLE_00520 1.3e-24 - - - S - - - Protein of unknown function (DUF1722)
GDHHKMLE_00521 2.01e-54 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
GDHHKMLE_00522 1.16e-243 - - - L - - - Transposase and inactivated derivatives, IS30 family
GDHHKMLE_00523 2.87e-213 yitS - - S - - - Uncharacterised protein, DegV family COG1307
GDHHKMLE_00524 4.21e-105 - - - K - - - Acetyltransferase (GNAT) family
GDHHKMLE_00525 0.0 - - - EGP - - - Major Facilitator
GDHHKMLE_00526 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GDHHKMLE_00527 1.21e-210 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
GDHHKMLE_00528 2.53e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
GDHHKMLE_00529 1.08e-279 yttB - - EGP - - - Major Facilitator
GDHHKMLE_00530 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GDHHKMLE_00531 4.97e-248 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
GDHHKMLE_00532 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GDHHKMLE_00533 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GDHHKMLE_00534 3.61e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GDHHKMLE_00535 3e-271 camS - - S - - - sex pheromone
GDHHKMLE_00536 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GDHHKMLE_00537 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GDHHKMLE_00538 5.65e-46 - - - S - - - Bacterial protein of unknown function (DUF898)
GDHHKMLE_00539 1.01e-179 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
GDHHKMLE_00540 5.72e-265 tcaA - - S ko:K21463 - ko00000 response to antibiotic
GDHHKMLE_00542 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
GDHHKMLE_00543 4.96e-73 - - - - - - - -
GDHHKMLE_00544 1.53e-88 - - - - - - - -
GDHHKMLE_00545 7.36e-94 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
GDHHKMLE_00546 7.39e-20 - - - - - - - -
GDHHKMLE_00547 1.34e-96 - - - S - - - acetyltransferase
GDHHKMLE_00548 0.0 yclK - - T - - - Histidine kinase
GDHHKMLE_00549 3.55e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
GDHHKMLE_00550 5.39e-92 - - - S - - - SdpI/YhfL protein family
GDHHKMLE_00552 1.4e-35 ytgB - - S - - - Transglycosylase associated protein
GDHHKMLE_00553 2.3e-23 - - - - - - - -
GDHHKMLE_00555 9.63e-61 - - - S - - - Phage gp6-like head-tail connector protein
GDHHKMLE_00556 0.0 - - - S ko:K06904 - ko00000 Phage capsid family
GDHHKMLE_00557 1.4e-281 - - - S - - - Phage portal protein
GDHHKMLE_00558 2.89e-27 - - - - - - - -
GDHHKMLE_00559 2.25e-64 - - - S - - - Protein of unknown function (DUF1093)
GDHHKMLE_00560 3.48e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
GDHHKMLE_00561 2.27e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
GDHHKMLE_00562 1.41e-241 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
GDHHKMLE_00563 4.7e-225 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GDHHKMLE_00564 1.41e-163 - - - P - - - integral membrane protein, YkoY family
GDHHKMLE_00568 1.11e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GDHHKMLE_00569 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GDHHKMLE_00570 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GDHHKMLE_00571 1.44e-256 - - - K - - - WYL domain
GDHHKMLE_00572 3.46e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
GDHHKMLE_00573 3.63e-90 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
GDHHKMLE_00574 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GDHHKMLE_00575 4.01e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GDHHKMLE_00576 1.98e-140 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GDHHKMLE_00577 1.02e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GDHHKMLE_00578 7.23e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GDHHKMLE_00579 5.26e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GDHHKMLE_00580 4.5e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GDHHKMLE_00581 6.88e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GDHHKMLE_00582 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GDHHKMLE_00583 3.55e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GDHHKMLE_00584 5.93e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GDHHKMLE_00585 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GDHHKMLE_00586 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GDHHKMLE_00587 8.67e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GDHHKMLE_00588 4.78e-35 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GDHHKMLE_00589 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GDHHKMLE_00590 2.61e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GDHHKMLE_00591 1.62e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GDHHKMLE_00592 5.74e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GDHHKMLE_00593 2.6e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GDHHKMLE_00594 4.07e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GDHHKMLE_00595 4.06e-303 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GDHHKMLE_00596 1.29e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GDHHKMLE_00597 4.15e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GDHHKMLE_00598 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GDHHKMLE_00599 5.37e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GDHHKMLE_00600 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GDHHKMLE_00601 1.26e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDHHKMLE_00602 5.46e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GDHHKMLE_00603 2.85e-141 - - - - - - - -
GDHHKMLE_00604 4.68e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDHHKMLE_00605 1.92e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDHHKMLE_00606 1.13e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDHHKMLE_00607 1.39e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GDHHKMLE_00608 5.14e-168 tipA - - K - - - TipAS antibiotic-recognition domain
GDHHKMLE_00609 1.5e-44 - - - - - - - -
GDHHKMLE_00610 7.1e-162 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GDHHKMLE_00611 2.5e-236 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GDHHKMLE_00612 1.06e-133 - - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_00613 2.98e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GDHHKMLE_00614 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GDHHKMLE_00615 5.94e-71 - - - - - - - -
GDHHKMLE_00616 2.54e-105 - - - - - - - -
GDHHKMLE_00617 3.91e-24 - - - S - - - Protein of unknown function (DUF2785)
GDHHKMLE_00618 1.62e-189 ssuC - - U ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GDHHKMLE_00619 1.19e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GDHHKMLE_00620 2.74e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GDHHKMLE_00621 0.0 yknV - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
GDHHKMLE_00622 4.73e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GDHHKMLE_00623 1.93e-213 - - - S - - - Tetratricopeptide repeat
GDHHKMLE_00624 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GDHHKMLE_00625 8.76e-61 - - - - - - - -
GDHHKMLE_00626 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GDHHKMLE_00628 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GDHHKMLE_00629 7.21e-222 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GDHHKMLE_00630 2e-309 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GDHHKMLE_00631 1.83e-189 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GDHHKMLE_00632 2.99e-147 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
GDHHKMLE_00633 9.02e-234 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GDHHKMLE_00634 5.12e-112 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GDHHKMLE_00635 9.93e-130 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
GDHHKMLE_00636 4.9e-83 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
GDHHKMLE_00637 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GDHHKMLE_00638 1.66e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GDHHKMLE_00639 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GDHHKMLE_00640 3.98e-186 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
GDHHKMLE_00641 6.15e-62 yktA - - S - - - Belongs to the UPF0223 family
GDHHKMLE_00642 2.05e-200 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
GDHHKMLE_00643 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
GDHHKMLE_00644 0.0 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GDHHKMLE_00645 1.15e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
GDHHKMLE_00646 1.42e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
GDHHKMLE_00647 5.94e-111 - - - S - - - E1-E2 ATPase
GDHHKMLE_00648 1.21e-142 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
GDHHKMLE_00649 1.95e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
GDHHKMLE_00650 2.43e-60 - - - S - - - Family of unknown function (DUF5322)
GDHHKMLE_00651 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GDHHKMLE_00652 2.41e-106 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GDHHKMLE_00653 2.99e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GDHHKMLE_00654 1.05e-125 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GDHHKMLE_00655 1.91e-298 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
GDHHKMLE_00656 1.04e-226 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GDHHKMLE_00657 3.46e-303 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GDHHKMLE_00658 5.32e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GDHHKMLE_00659 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GDHHKMLE_00660 1.28e-198 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GDHHKMLE_00661 1.88e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GDHHKMLE_00662 4.15e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GDHHKMLE_00663 1.74e-190 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Phosphate acetyl/butaryl transferase
GDHHKMLE_00664 1.51e-259 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Acetokinase family
GDHHKMLE_00665 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
GDHHKMLE_00666 1.45e-235 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
GDHHKMLE_00667 1.24e-233 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
GDHHKMLE_00668 1.32e-243 bfmBB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
GDHHKMLE_00669 7.12e-226 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GDHHKMLE_00670 2.74e-248 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
GDHHKMLE_00671 8.55e-67 - - - S - - - MazG-like family
GDHHKMLE_00672 0.0 FbpA - - K - - - Fibronectin-binding protein
GDHHKMLE_00673 2.95e-205 - - - S - - - EDD domain protein, DegV family
GDHHKMLE_00674 9.61e-129 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
GDHHKMLE_00675 2.32e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GDHHKMLE_00676 7.41e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GDHHKMLE_00677 8.39e-144 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GDHHKMLE_00678 5.88e-295 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GDHHKMLE_00679 7.58e-134 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
GDHHKMLE_00680 1.99e-145 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GDHHKMLE_00681 6.52e-159 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GDHHKMLE_00682 1.42e-169 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GDHHKMLE_00683 1.01e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GDHHKMLE_00684 6.09e-70 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
GDHHKMLE_00685 5.93e-261 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GDHHKMLE_00686 2.4e-143 - - - C - - - Nitroreductase family
GDHHKMLE_00687 1.33e-91 - - - K - - - Acetyltransferase (GNAT) domain
GDHHKMLE_00688 8.72e-64 - - - K - - - Acetyltransferase (GNAT) domain
GDHHKMLE_00689 2.37e-53 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
GDHHKMLE_00690 1.86e-205 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
GDHHKMLE_00691 2.9e-158 - - - T - - - Transcriptional regulatory protein, C terminal
GDHHKMLE_00692 2.98e-220 kinG - - T - - - Histidine kinase-like ATPases
GDHHKMLE_00693 5.18e-174 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_00694 0.0 XK27_05700 - - V ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
GDHHKMLE_00695 1.45e-78 - - - - - - - -
GDHHKMLE_00696 5.77e-267 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
GDHHKMLE_00697 7.95e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GDHHKMLE_00698 2.6e-232 - - - K - - - LysR substrate binding domain
GDHHKMLE_00699 6.03e-216 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GDHHKMLE_00700 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
GDHHKMLE_00701 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GDHHKMLE_00702 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GDHHKMLE_00704 6.92e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GDHHKMLE_00705 5.38e-219 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GDHHKMLE_00706 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GDHHKMLE_00707 4.87e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GDHHKMLE_00708 1.66e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
GDHHKMLE_00709 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GDHHKMLE_00710 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GDHHKMLE_00711 1.36e-118 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GDHHKMLE_00712 2.5e-33 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GDHHKMLE_00713 2.91e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GDHHKMLE_00714 2.53e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GDHHKMLE_00715 3.57e-53 - - - K - - - Helix-turn-helix domain
GDHHKMLE_00716 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
GDHHKMLE_00717 2.95e-54 yozE - - S - - - Belongs to the UPF0346 family
GDHHKMLE_00718 2.49e-110 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GDHHKMLE_00719 3.18e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
GDHHKMLE_00720 3.53e-193 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
GDHHKMLE_00721 2.83e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
GDHHKMLE_00722 1.83e-148 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
GDHHKMLE_00723 3.64e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GDHHKMLE_00724 2e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GDHHKMLE_00725 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_00726 2.95e-110 - - - - - - - -
GDHHKMLE_00727 5.31e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GDHHKMLE_00728 8.71e-200 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GDHHKMLE_00729 1.52e-302 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GDHHKMLE_00730 1.2e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GDHHKMLE_00731 7.41e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GDHHKMLE_00732 1.72e-303 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GDHHKMLE_00733 2.04e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GDHHKMLE_00734 1.68e-104 - - - M - - - Lysin motif
GDHHKMLE_00735 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GDHHKMLE_00736 2.4e-230 - - - S - - - Helix-turn-helix domain
GDHHKMLE_00737 1.92e-59 fer - - C ko:K05337 - ko00000 4Fe-4S single cluster domain of Ferredoxin I
GDHHKMLE_00738 4.35e-123 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GDHHKMLE_00739 3.15e-175 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GDHHKMLE_00740 8.74e-139 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GDHHKMLE_00741 2.17e-159 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GDHHKMLE_00742 1.59e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GDHHKMLE_00743 9.95e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
GDHHKMLE_00744 5.96e-207 yitL - - S ko:K00243 - ko00000 S1 domain
GDHHKMLE_00745 4.31e-95 ytwI - - S - - - Protein of unknown function (DUF441)
GDHHKMLE_00746 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GDHHKMLE_00747 1.82e-226 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GDHHKMLE_00748 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GDHHKMLE_00749 8.1e-36 - - - S - - - Protein of unknown function (DUF2929)
GDHHKMLE_00750 2.47e-184 - - - - - - - -
GDHHKMLE_00751 0.0 ycjM 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
GDHHKMLE_00752 6.3e-123 - - - K - - - Domain of unknown function (DUF1836)
GDHHKMLE_00753 1.35e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GDHHKMLE_00754 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GDHHKMLE_00755 4.1e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
GDHHKMLE_00756 2.13e-182 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
GDHHKMLE_00757 1.1e-232 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GDHHKMLE_00758 0.0 oatA - - I - - - Acyltransferase
GDHHKMLE_00759 3.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GDHHKMLE_00760 2.78e-170 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
GDHHKMLE_00761 1.13e-217 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GDHHKMLE_00762 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
GDHHKMLE_00763 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GDHHKMLE_00764 7.68e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_00765 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GDHHKMLE_00766 3.33e-28 - - - - - - - -
GDHHKMLE_00767 2.28e-63 - - - S - - - mazG nucleotide pyrophosphohydrolase
GDHHKMLE_00768 2.74e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GDHHKMLE_00769 1.09e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GDHHKMLE_00770 1.51e-146 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
GDHHKMLE_00771 3.99e-258 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GDHHKMLE_00772 5.81e-218 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GDHHKMLE_00773 1.05e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GDHHKMLE_00774 1.19e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
GDHHKMLE_00775 1.79e-138 - - - S - - - CYTH
GDHHKMLE_00776 1.15e-150 yjbH - - Q - - - Thioredoxin
GDHHKMLE_00777 1.16e-270 coiA - - S ko:K06198 - ko00000 Competence protein
GDHHKMLE_00778 3.93e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
GDHHKMLE_00779 5.05e-52 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
GDHHKMLE_00780 0.0 cpdA - - S - - - Calcineurin-like phosphoesterase
GDHHKMLE_00781 3.02e-296 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
GDHHKMLE_00783 2.31e-110 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
GDHHKMLE_00784 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GDHHKMLE_00785 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GDHHKMLE_00787 4.23e-120 - - - F - - - NUDIX domain
GDHHKMLE_00788 7.92e-182 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GDHHKMLE_00789 1.58e-45 yhcC - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GDHHKMLE_00790 5.43e-166 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GDHHKMLE_00791 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GDHHKMLE_00792 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GDHHKMLE_00793 1.05e-154 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
GDHHKMLE_00794 7.54e-155 - - - S - - - Domain of unknown function (DUF4811)
GDHHKMLE_00795 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GDHHKMLE_00796 3.99e-106 - - - K - - - MerR HTH family regulatory protein
GDHHKMLE_00797 0.0 mdr - - EGP - - - Major Facilitator
GDHHKMLE_00798 1.52e-265 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GDHHKMLE_00799 8.02e-91 - - - - - - - -
GDHHKMLE_00802 6.41e-127 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GDHHKMLE_00803 4.39e-244 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GDHHKMLE_00804 8.81e-288 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
GDHHKMLE_00805 1e-221 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GDHHKMLE_00806 1.34e-211 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GDHHKMLE_00807 1.05e-181 terC - - P - - - Integral membrane protein TerC family
GDHHKMLE_00808 1.27e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GDHHKMLE_00809 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GDHHKMLE_00810 1.29e-60 ylxQ - - J - - - ribosomal protein
GDHHKMLE_00811 9.63e-61 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
GDHHKMLE_00812 1.61e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GDHHKMLE_00813 1.28e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GDHHKMLE_00814 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GDHHKMLE_00815 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GDHHKMLE_00816 1.43e-291 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GDHHKMLE_00817 7.66e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GDHHKMLE_00818 5.24e-180 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GDHHKMLE_00819 4.96e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GDHHKMLE_00820 5.62e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GDHHKMLE_00821 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GDHHKMLE_00822 1.18e-182 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GDHHKMLE_00823 5.19e-59 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
GDHHKMLE_00824 1.68e-167 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
GDHHKMLE_00825 5.54e-85 - - - S - - - P63C domain
GDHHKMLE_00826 1.84e-283 - - - M - - - Glycosyl hydrolases family 25
GDHHKMLE_00827 3.63e-64 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
GDHHKMLE_00828 8.27e-20 - - - - - - - -
GDHHKMLE_00831 1.34e-64 - - - S - - - cellulase activity
GDHHKMLE_00832 4.08e-47 - - - - - - - -
GDHHKMLE_00833 3.29e-228 - - - C - - - Cytochrome bd terminal oxidase subunit II
GDHHKMLE_00834 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit I
GDHHKMLE_00835 3.26e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GDHHKMLE_00836 3.65e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GDHHKMLE_00837 1.36e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GDHHKMLE_00838 5.2e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GDHHKMLE_00839 3.02e-162 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GDHHKMLE_00840 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GDHHKMLE_00841 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GDHHKMLE_00842 1.24e-257 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GDHHKMLE_00843 4.07e-43 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
GDHHKMLE_00844 2.93e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GDHHKMLE_00845 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GDHHKMLE_00846 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
GDHHKMLE_00847 2.99e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GDHHKMLE_00848 5.29e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GDHHKMLE_00849 2.87e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
GDHHKMLE_00851 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GDHHKMLE_00852 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GDHHKMLE_00853 3.8e-175 labL - - S - - - Putative threonine/serine exporter
GDHHKMLE_00854 1.48e-104 - - - S - - - Threonine/Serine exporter, ThrE
GDHHKMLE_00855 4.92e-285 amd - - E - - - Peptidase family M20/M25/M40
GDHHKMLE_00856 4.79e-250 ypjH - - C ko:K08317 - ko00000,ko01000 dehydrogenase
GDHHKMLE_00857 5.71e-238 - - - M - - - Leucine rich repeats (6 copies)
GDHHKMLE_00858 0.0 yvcC - - M - - - Cna protein B-type domain
GDHHKMLE_00859 9.16e-128 yvcC - - M - - - Cna protein B-type domain
GDHHKMLE_00860 2.37e-161 - - - M - - - domain protein
GDHHKMLE_00861 4.86e-234 - - - M - - - LPXTG cell wall anchor motif
GDHHKMLE_00862 6.01e-138 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GDHHKMLE_00863 1.81e-88 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GDHHKMLE_00864 1.94e-163 XK27_12140 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GDHHKMLE_00865 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
GDHHKMLE_00866 7.73e-164 - - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
GDHHKMLE_00867 5.71e-250 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GDHHKMLE_00868 3.24e-179 - - - V - - - ATPases associated with a variety of cellular activities
GDHHKMLE_00869 1.04e-266 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GDHHKMLE_00870 2.8e-118 - - - - - - - -
GDHHKMLE_00871 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GDHHKMLE_00872 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GDHHKMLE_00873 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GDHHKMLE_00874 7.62e-269 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
GDHHKMLE_00875 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GDHHKMLE_00876 3.48e-215 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
GDHHKMLE_00877 2.45e-184 gntR - - K - - - rpiR family
GDHHKMLE_00878 4.55e-208 yvgN - - C - - - Aldo keto reductase
GDHHKMLE_00879 2.71e-182 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GDHHKMLE_00880 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GDHHKMLE_00881 5.9e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GDHHKMLE_00882 4.55e-302 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GDHHKMLE_00883 2.81e-278 hpk31 - - T - - - Histidine kinase
GDHHKMLE_00884 1.68e-156 vanR - - K - - - response regulator
GDHHKMLE_00885 1.23e-157 - - - - - - - -
GDHHKMLE_00886 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GDHHKMLE_00887 6.38e-172 - - - S - - - Protein of unknown function (DUF1129)
GDHHKMLE_00888 2.8e-236 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GDHHKMLE_00889 1.33e-39 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
GDHHKMLE_00890 5.25e-200 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GDHHKMLE_00891 4.28e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
GDHHKMLE_00892 7.98e-188 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GDHHKMLE_00893 3.22e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
GDHHKMLE_00894 4.01e-87 - - - - - - - -
GDHHKMLE_00895 2.72e-164 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
GDHHKMLE_00896 1.02e-137 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
GDHHKMLE_00897 6.93e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GDHHKMLE_00898 1.42e-195 - - - S - - - Protein of unknown function (DUF979)
GDHHKMLE_00899 2.66e-147 - - - S - - - Protein of unknown function (DUF969)
GDHHKMLE_00900 1.97e-92 asp2 - - S - - - Asp23 family, cell envelope-related function
GDHHKMLE_00901 2.11e-88 asp23 - - S - - - Asp23 family, cell envelope-related function
GDHHKMLE_00902 4.15e-34 - - - - - - - -
GDHHKMLE_00903 1.16e-112 - - - S - - - Protein conserved in bacteria
GDHHKMLE_00904 1.93e-52 - - - S - - - Transglycosylase associated protein
GDHHKMLE_00905 6.51e-94 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
GDHHKMLE_00907 3.38e-72 - - - S - - - Enterocin A Immunity
GDHHKMLE_00908 2.06e-87 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
GDHHKMLE_00909 8.67e-34 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
GDHHKMLE_00910 1.41e-06 - - - S - - - SpoVT / AbrB like domain
GDHHKMLE_00912 1.65e-08 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
GDHHKMLE_00913 5.65e-229 ydhF - - S - - - Aldo keto reductase
GDHHKMLE_00914 2.03e-165 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GDHHKMLE_00915 3.51e-272 yqiG - - C - - - Oxidoreductase
GDHHKMLE_00916 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GDHHKMLE_00917 6.05e-171 - - - - - - - -
GDHHKMLE_00918 6.42e-28 - - - - - - - -
GDHHKMLE_00919 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GDHHKMLE_00920 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GDHHKMLE_00921 1.14e-72 - - - - - - - -
GDHHKMLE_00922 5.15e-305 - - - EGP - - - Major Facilitator Superfamily
GDHHKMLE_00923 0.0 sufI - - Q - - - Multicopper oxidase
GDHHKMLE_00924 1.53e-35 - - - - - - - -
GDHHKMLE_00925 7.75e-145 - - - P - - - Cation efflux family
GDHHKMLE_00926 7.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
GDHHKMLE_00927 1.09e-224 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GDHHKMLE_00928 1.69e-184 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
GDHHKMLE_00929 2.78e-169 - 3.6.3.35 - P ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
GDHHKMLE_00930 0.0 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family
GDHHKMLE_00931 6.85e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GDHHKMLE_00932 6.75e-215 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GDHHKMLE_00933 1.35e-150 - - - GM - - - NmrA-like family
GDHHKMLE_00934 4.49e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
GDHHKMLE_00935 7.04e-102 - - - - - - - -
GDHHKMLE_00936 2.06e-32 - - - M - - - domain protein
GDHHKMLE_00937 0.0 poxL 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GDHHKMLE_00938 2.6e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
GDHHKMLE_00939 4.66e-267 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
GDHHKMLE_00940 4.04e-265 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GDHHKMLE_00941 7.23e-66 - - - - - - - -
GDHHKMLE_00942 1.58e-203 - - - G - - - Xylose isomerase domain protein TIM barrel
GDHHKMLE_00943 1.05e-132 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
GDHHKMLE_00944 7.52e-200 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 converts alpha-aldose to the beta-anomer
GDHHKMLE_00945 2.56e-270 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GDHHKMLE_00946 4.33e-132 - - - S - - - ECF transporter, substrate-specific component
GDHHKMLE_00948 1.4e-105 - - - K - - - Acetyltransferase GNAT Family
GDHHKMLE_00949 3.33e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GDHHKMLE_00950 3.35e-167 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_00951 2.83e-188 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GDHHKMLE_00952 1.67e-196 XK27_08835 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_00953 1.17e-95 - - - - - - - -
GDHHKMLE_00954 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GDHHKMLE_00955 4.84e-278 - - - V - - - Beta-lactamase
GDHHKMLE_00956 3.41e-193 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GDHHKMLE_00957 9.09e-280 - - - V - - - Beta-lactamase
GDHHKMLE_00958 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GDHHKMLE_00959 1.62e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
GDHHKMLE_00960 7.45e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GDHHKMLE_00961 1.13e-177 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GDHHKMLE_00962 7.06e-274 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
GDHHKMLE_00964 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GDHHKMLE_00965 8.03e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GDHHKMLE_00967 3.38e-56 - - - - - - - -
GDHHKMLE_00968 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GDHHKMLE_00969 4.13e-109 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
GDHHKMLE_00970 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GDHHKMLE_00971 2.51e-28 - - - - - - - -
GDHHKMLE_00972 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GDHHKMLE_00973 3.27e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GDHHKMLE_00974 1.29e-105 yjhE - - S - - - Phage tail protein
GDHHKMLE_00975 4.06e-303 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GDHHKMLE_00976 3.32e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GDHHKMLE_00977 4.03e-164 gpm2 - - G - - - Phosphoglycerate mutase family
GDHHKMLE_00978 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GDHHKMLE_00979 2.68e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_00980 0.0 - - - E - - - Amino Acid
GDHHKMLE_00981 2.01e-210 - - - I - - - Diacylglycerol kinase catalytic domain
GDHHKMLE_00982 6.49e-304 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GDHHKMLE_00983 4.16e-202 nodB3 - - G - - - Polysaccharide deacetylase
GDHHKMLE_00984 0.0 - - - M - - - Sulfatase
GDHHKMLE_00985 1.15e-111 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GDHHKMLE_00986 3.48e-103 ywiB - - S - - - Domain of unknown function (DUF1934)
GDHHKMLE_00987 4.89e-201 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
GDHHKMLE_00988 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
GDHHKMLE_00989 4.73e-102 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GDHHKMLE_00990 3.04e-237 - - - S - - - DUF218 domain
GDHHKMLE_00991 1.31e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GDHHKMLE_00992 1.95e-104 - - - E - - - glutamate:sodium symporter activity
GDHHKMLE_00993 3.78e-74 nudA - - S - - - ASCH
GDHHKMLE_00994 2.2e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GDHHKMLE_00995 3.29e-299 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GDHHKMLE_00996 4.21e-285 ysaA - - V - - - RDD family
GDHHKMLE_00997 2.91e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GDHHKMLE_00998 1.06e-153 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_00999 5.89e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
GDHHKMLE_01000 1.99e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GDHHKMLE_01001 6.63e-232 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GDHHKMLE_01002 4.13e-51 veg - - S - - - Biofilm formation stimulator VEG
GDHHKMLE_01003 2.04e-202 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GDHHKMLE_01004 5.57e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GDHHKMLE_01005 9.1e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
GDHHKMLE_01006 3.64e-104 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
GDHHKMLE_01007 1.35e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
GDHHKMLE_01008 7.08e-220 yqhA - - G - - - Aldose 1-epimerase
GDHHKMLE_01009 6.82e-159 - - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GDHHKMLE_01010 3.52e-200 - - - T - - - GHKL domain
GDHHKMLE_01011 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
GDHHKMLE_01012 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
GDHHKMLE_01013 9.13e-82 - - - - - - - -
GDHHKMLE_01014 1.26e-85 - - - - - - - -
GDHHKMLE_01015 0.0 frdC 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
GDHHKMLE_01016 3.82e-249 - - - GKT - - - transcriptional antiterminator
GDHHKMLE_01017 1.32e-63 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GDHHKMLE_01018 1.88e-290 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GDHHKMLE_01019 2.92e-89 - - - - - - - -
GDHHKMLE_01020 6.47e-208 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
GDHHKMLE_01021 2.92e-145 - - - S - - - Zeta toxin
GDHHKMLE_01022 2.63e-202 - - - K - - - Sugar-specific transcriptional regulator TrmB
GDHHKMLE_01023 9.64e-191 - - - S - - - Sulfite exporter TauE/SafE
GDHHKMLE_01024 1.68e-228 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
GDHHKMLE_01025 2.99e-106 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01026 2.03e-153 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_01027 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
GDHHKMLE_01028 8.76e-193 - - - S - - - hydrolase
GDHHKMLE_01029 1.49e-58 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
GDHHKMLE_01030 9.48e-237 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
GDHHKMLE_01031 2.46e-108 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
GDHHKMLE_01032 4.39e-177 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
GDHHKMLE_01033 7.9e-196 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
GDHHKMLE_01034 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GDHHKMLE_01035 8.75e-90 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
GDHHKMLE_01036 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GDHHKMLE_01037 0.0 - - - S - - - Phage tail protein
GDHHKMLE_01038 0.0 - - - L - - - Phage tail tape measure protein TP901
GDHHKMLE_01040 6.3e-121 - - - S - - - Phage tail tube protein
GDHHKMLE_01041 1.46e-84 - - - - - - - -
GDHHKMLE_01042 5.09e-93 - - - - - - - -
GDHHKMLE_01043 1.11e-89 - - - - - - - -
GDHHKMLE_01044 1.09e-61 - - - - - - - -
GDHHKMLE_01045 3.52e-273 - - - S - - - Phage capsid family
GDHHKMLE_01046 1.42e-162 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
GDHHKMLE_01047 6.12e-278 - - - S - - - Phage portal protein
GDHHKMLE_01048 0.0 - - - S - - - Phage Terminase
GDHHKMLE_01049 4.72e-53 - - - - - - - -
GDHHKMLE_01050 1.98e-40 - - - L - - - HNH nucleases
GDHHKMLE_01051 8.3e-60 - - - - - - - -
GDHHKMLE_01053 1.98e-62 - - - - - - - -
GDHHKMLE_01054 2.71e-301 - - - - - - - -
GDHHKMLE_01056 9.37e-96 - - - - - - - -
GDHHKMLE_01058 3.43e-55 - - - S - - - YopX protein
GDHHKMLE_01060 1.05e-77 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
GDHHKMLE_01061 1.49e-23 - - - - - - - -
GDHHKMLE_01064 1.92e-43 - - - S - - - Protein of unknown function (DUF1642)
GDHHKMLE_01067 1.09e-29 - - - - - - - -
GDHHKMLE_01068 2.86e-74 rusA - - L - - - Endodeoxyribonuclease RusA
GDHHKMLE_01070 2.81e-297 - - - S - - - DNA helicase activity
GDHHKMLE_01071 1.43e-147 - - - S - - - calcium ion binding
GDHHKMLE_01076 1.66e-59 - - - S - - - Domain of unknown function (DUF1883)
GDHHKMLE_01078 6.67e-156 - - - S - - - ORF6N domain
GDHHKMLE_01081 2.7e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
GDHHKMLE_01082 1.07e-29 - - - E - - - Zn peptidase
GDHHKMLE_01083 3.45e-36 - - - M - - - Host cell surface-exposed lipoprotein
GDHHKMLE_01088 2.16e-51 int2 - - L - - - Belongs to the 'phage' integrase family
GDHHKMLE_01089 2.51e-27 int3 - - L - - - Belongs to the 'phage' integrase family
GDHHKMLE_01090 3.44e-159 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GDHHKMLE_01091 2.26e-291 yhdG - - E ko:K03294 - ko00000 Amino Acid
GDHHKMLE_01092 4.28e-181 yejC - - S - - - Protein of unknown function (DUF1003)
GDHHKMLE_01093 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_01094 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_01095 1.39e-40 yneF - - S ko:K09976 - ko00000 UPF0154 protein
GDHHKMLE_01096 2.84e-48 ynzC - - S - - - UPF0291 protein
GDHHKMLE_01097 3.28e-28 - - - - - - - -
GDHHKMLE_01098 2e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GDHHKMLE_01099 1.76e-185 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GDHHKMLE_01100 2.16e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GDHHKMLE_01101 1.55e-51 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
GDHHKMLE_01102 2.97e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GDHHKMLE_01103 1.52e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GDHHKMLE_01104 1.26e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GDHHKMLE_01105 7.91e-70 - - - - - - - -
GDHHKMLE_01106 6.11e-231 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GDHHKMLE_01107 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GDHHKMLE_01108 8.02e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GDHHKMLE_01109 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GDHHKMLE_01110 1.16e-193 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GDHHKMLE_01111 1.3e-215 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01112 1.62e-228 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDHHKMLE_01113 4.24e-247 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDHHKMLE_01114 3.21e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GDHHKMLE_01115 1.35e-239 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GDHHKMLE_01116 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GDHHKMLE_01117 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
GDHHKMLE_01118 4.8e-74 yloU - - S - - - Asp23 family, cell envelope-related function
GDHHKMLE_01119 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GDHHKMLE_01120 7.21e-164 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GDHHKMLE_01121 4.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GDHHKMLE_01122 5.6e-221 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GDHHKMLE_01123 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GDHHKMLE_01124 5.22e-174 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GDHHKMLE_01125 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GDHHKMLE_01126 3.95e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GDHHKMLE_01127 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GDHHKMLE_01128 5.63e-275 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GDHHKMLE_01129 2.94e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GDHHKMLE_01130 1.7e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GDHHKMLE_01131 1.7e-72 - - - S ko:K07001 - ko00000 Patatin-like phospholipase
GDHHKMLE_01132 2.71e-66 - - - - - - - -
GDHHKMLE_01134 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GDHHKMLE_01135 4.19e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GDHHKMLE_01136 8.09e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GDHHKMLE_01137 5.21e-189 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GDHHKMLE_01138 1.42e-43 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GDHHKMLE_01139 1.74e-292 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GDHHKMLE_01140 7.39e-192 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GDHHKMLE_01141 1.12e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GDHHKMLE_01142 9.44e-99 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
GDHHKMLE_01143 3.51e-131 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GDHHKMLE_01145 1.69e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GDHHKMLE_01146 1.6e-63 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GDHHKMLE_01147 1.77e-74 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
GDHHKMLE_01148 5.83e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GDHHKMLE_01149 1.17e-16 - - - - - - - -
GDHHKMLE_01152 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GDHHKMLE_01153 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GDHHKMLE_01154 1.32e-80 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
GDHHKMLE_01155 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
GDHHKMLE_01156 4.73e-304 ynbB - - P - - - aluminum resistance
GDHHKMLE_01157 1.22e-219 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GDHHKMLE_01158 9.56e-35 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
GDHHKMLE_01159 1.93e-96 yqhL - - P - - - Rhodanese-like protein
GDHHKMLE_01160 1.13e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GDHHKMLE_01161 6.79e-55 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
GDHHKMLE_01162 1.33e-157 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
GDHHKMLE_01163 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GDHHKMLE_01164 3.23e-137 - - - S - - - Bacterial membrane protein YfhO
GDHHKMLE_01165 1.32e-170 - - - S - - - Bacterial membrane protein YfhO
GDHHKMLE_01166 5.15e-237 - - - S - - - Bacterial membrane protein YfhO
GDHHKMLE_01167 9.49e-71 yneR - - S - - - Belongs to the HesB IscA family
GDHHKMLE_01168 2.04e-149 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
GDHHKMLE_01169 2.2e-230 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDHHKMLE_01170 3.14e-164 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
GDHHKMLE_01171 6.8e-129 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GDHHKMLE_01172 6.25e-204 - - - C - - - Alcohol dehydrogenase GroES-like domain
GDHHKMLE_01173 6.12e-157 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
GDHHKMLE_01174 6.46e-242 mhqA_2 - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GDHHKMLE_01175 3.47e-191 ykcA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GDHHKMLE_01176 6.63e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
GDHHKMLE_01177 2.37e-259 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
GDHHKMLE_01178 3.95e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
GDHHKMLE_01179 2.24e-156 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GDHHKMLE_01180 3.21e-142 yqeK - - H - - - Hydrolase, HD family
GDHHKMLE_01181 6.85e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GDHHKMLE_01182 3.83e-175 yccK - - Q - - - ubiE/COQ5 methyltransferase family
GDHHKMLE_01183 7.26e-265 ylbM - - S - - - Belongs to the UPF0348 family
GDHHKMLE_01184 2.58e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
GDHHKMLE_01185 5.74e-52 - - - S - - - Psort location Cytoplasmic, score
GDHHKMLE_01186 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GDHHKMLE_01187 1.01e-157 csrR - - K - - - response regulator
GDHHKMLE_01188 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDHHKMLE_01189 2.58e-228 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GDHHKMLE_01190 4.17e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GDHHKMLE_01191 1.28e-177 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GDHHKMLE_01192 8.88e-122 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GDHHKMLE_01193 2e-86 yodB - - K - - - Transcriptional regulator, HxlR family
GDHHKMLE_01194 3.55e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GDHHKMLE_01195 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GDHHKMLE_01196 2.12e-264 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GDHHKMLE_01197 3.43e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GDHHKMLE_01198 1.05e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GDHHKMLE_01199 1.44e-174 - - - S - - - Phage tail protein
GDHHKMLE_01200 0.0 - - - D - - - Phage tail tape measure protein
GDHHKMLE_01201 3.44e-74 - - - - - - - -
GDHHKMLE_01202 5.4e-69 - - - S - - - Phage tail assembly chaperone protein, TAC
GDHHKMLE_01203 2.29e-123 - - - S - - - Phage tail tube protein
GDHHKMLE_01204 1.12e-90 - - - S - - - Protein of unknown function (DUF3168)
GDHHKMLE_01205 7.05e-72 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GDHHKMLE_01206 6.4e-65 - - - - - - - -
GDHHKMLE_01207 6.21e-81 - - - S - - - Phage gp6-like head-tail connector protein
GDHHKMLE_01208 2.05e-198 - - - - - - - -
GDHHKMLE_01209 4.18e-237 - - - S - - - Phage major capsid protein E
GDHHKMLE_01210 4.78e-62 - - - - - - - -
GDHHKMLE_01211 1.57e-112 - - - S - - - Domain of unknown function (DUF4355)
GDHHKMLE_01212 1.05e-22 - - - - - - - -
GDHHKMLE_01215 6.85e-228 - - - S - - - head morphogenesis protein, SPP1 gp7 family
GDHHKMLE_01216 0.0 - - - S - - - Phage portal protein
GDHHKMLE_01217 5.17e-312 - - - S - - - Terminase-like family
GDHHKMLE_01218 4.84e-30 - - - L ko:K07474 - ko00000 Terminase small subunit
GDHHKMLE_01221 2.12e-275 - - - S - - - GcrA cell cycle regulator
GDHHKMLE_01223 0.000413 - - - S - - - CsbD-like
GDHHKMLE_01224 3.51e-88 - - - K - - - IrrE N-terminal-like domain
GDHHKMLE_01226 3.8e-24 arpU - - S - - - ArpU family
GDHHKMLE_01230 3.2e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
GDHHKMLE_01231 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
GDHHKMLE_01232 1.97e-124 - - - K - - - Cupin domain
GDHHKMLE_01233 9.1e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GDHHKMLE_01234 1.44e-189 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01235 2.88e-187 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01236 8.49e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_01238 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
GDHHKMLE_01239 5.23e-144 - - - K - - - Transcriptional regulator
GDHHKMLE_01240 1.72e-236 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_01241 1.09e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
GDHHKMLE_01242 1.1e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GDHHKMLE_01243 3.17e-214 ybbR - - S - - - YbbR-like protein
GDHHKMLE_01244 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GDHHKMLE_01245 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GDHHKMLE_01247 0.0 pepF2 - - E - - - Oligopeptidase F
GDHHKMLE_01248 5.56e-105 - - - S - - - VanZ like family
GDHHKMLE_01249 5.85e-169 yebC - - K - - - Transcriptional regulatory protein
GDHHKMLE_01250 6.56e-193 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
GDHHKMLE_01251 1.61e-190 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GDHHKMLE_01252 6.78e-136 - - - S - - - Leucine-rich repeat (LRR) protein
GDHHKMLE_01253 8.71e-26 - - - S - - - Leucine-rich repeat (LRR) protein
GDHHKMLE_01254 3.15e-61 - - - S - - - Leucine-rich repeat (LRR) protein
GDHHKMLE_01255 1.03e-57 - - - - - - - -
GDHHKMLE_01256 1.51e-219 - - - S - - - Cell surface protein
GDHHKMLE_01257 3.65e-90 - - - S - - - WxL domain surface cell wall-binding
GDHHKMLE_01258 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GDHHKMLE_01259 8.86e-46 - - - - - - - -
GDHHKMLE_01260 2.87e-157 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_01261 6.84e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
GDHHKMLE_01262 1.27e-270 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GDHHKMLE_01263 1.01e-183 - - - - - - - -
GDHHKMLE_01265 7.63e-25 - - - - - - - -
GDHHKMLE_01266 5.18e-221 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GDHHKMLE_01267 2.26e-205 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
GDHHKMLE_01268 4.94e-214 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GDHHKMLE_01269 2.11e-273 - - - EGP - - - Major Facilitator Superfamily
GDHHKMLE_01270 6.47e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GDHHKMLE_01271 5.97e-179 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GDHHKMLE_01272 1.56e-204 - - - G - - - Xylose isomerase-like TIM barrel
GDHHKMLE_01273 4.54e-209 - - - K - - - Transcriptional regulator, LysR family
GDHHKMLE_01274 6.74e-117 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
GDHHKMLE_01275 9.93e-247 ycaM - - E - - - amino acid
GDHHKMLE_01276 2.76e-110 - 2.7.1.204 - G ko:K20112 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GDHHKMLE_01277 5.42e-67 - 2.7.1.204 - G ko:K20113 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GDHHKMLE_01278 0.0 gatC - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GDHHKMLE_01279 2.82e-36 - - - - - - - -
GDHHKMLE_01280 1.83e-159 - - - S - - - Domain of unknown function (DUF4867)
GDHHKMLE_01281 1.75e-225 lacC 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
GDHHKMLE_01282 4.19e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
GDHHKMLE_01283 2.62e-121 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
GDHHKMLE_01284 1.25e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
GDHHKMLE_01285 1.68e-180 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
GDHHKMLE_01286 5.3e-150 - - - S - - - HAD hydrolase, family IA, variant
GDHHKMLE_01287 1.31e-269 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GDHHKMLE_01288 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
GDHHKMLE_01289 6.8e-21 - - - - - - - -
GDHHKMLE_01291 7.42e-112 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GDHHKMLE_01293 6.26e-270 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
GDHHKMLE_01294 9.1e-191 - - - I - - - alpha/beta hydrolase fold
GDHHKMLE_01295 3.04e-156 yrkL - - S - - - Flavodoxin-like fold
GDHHKMLE_01297 1.06e-112 - - - S - - - Short repeat of unknown function (DUF308)
GDHHKMLE_01298 4.53e-152 - - - S - - - Psort location Cytoplasmic, score
GDHHKMLE_01299 2.72e-198 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GDHHKMLE_01300 1.94e-251 - - - - - - - -
GDHHKMLE_01302 3.99e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
GDHHKMLE_01303 6.5e-22 - - - - - - - -
GDHHKMLE_01305 1.27e-57 - - - S - - - Protein of unknown function (DUF1642)
GDHHKMLE_01307 2.87e-172 - - - S - - - C-5 cytosine-specific DNA methylase
GDHHKMLE_01308 1.09e-79 - - - S - - - Protein of unknown function (DUF1064)
GDHHKMLE_01311 5.02e-153 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
GDHHKMLE_01312 2.03e-71 - - - L - - - Replication initiation and membrane attachment
GDHHKMLE_01313 2.53e-188 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
GDHHKMLE_01314 2.41e-199 recT - - L ko:K07455 - ko00000,ko03400 RecT family
GDHHKMLE_01316 2.08e-22 - - - - - - - -
GDHHKMLE_01320 1.31e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
GDHHKMLE_01321 2.12e-37 - - - K - - - transcriptional
GDHHKMLE_01323 2.12e-93 - - - - - - - -
GDHHKMLE_01324 1.7e-72 - - - - - - - -
GDHHKMLE_01325 1.03e-277 - - - J - - - Domain of unknown function (DUF4041)
GDHHKMLE_01328 2.01e-69 - - - S - - - Pyridoxamine 5'-phosphate oxidase
GDHHKMLE_01331 7.87e-127 - - - L - - - Belongs to the 'phage' integrase family
GDHHKMLE_01332 1.37e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GDHHKMLE_01333 4.18e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GDHHKMLE_01335 1.92e-283 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GDHHKMLE_01336 3.47e-186 - - - K - - - acetyltransferase
GDHHKMLE_01337 9.83e-86 - - - - - - - -
GDHHKMLE_01338 3.97e-276 yceI - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
GDHHKMLE_01339 2.22e-48 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GDHHKMLE_01340 1.89e-89 - - - S - - - Domain of unknown function (DUF3284)
GDHHKMLE_01342 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDHHKMLE_01343 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
GDHHKMLE_01344 1.01e-171 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GDHHKMLE_01345 4.83e-175 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
GDHHKMLE_01346 0.0 - 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Helix-hairpin-helix containing domain
GDHHKMLE_01347 7.21e-102 - - - - - - - -
GDHHKMLE_01348 9.27e-77 - - - S - - - WxL domain surface cell wall-binding
GDHHKMLE_01349 7.99e-185 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
GDHHKMLE_01350 4.34e-130 hyuA - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
GDHHKMLE_01351 5.53e-175 - - - - - - - -
GDHHKMLE_01352 0.0 - - - S - - - Protein of unknown function (DUF1524)
GDHHKMLE_01353 3.51e-77 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GDHHKMLE_01354 2.77e-220 - - - L - - - Belongs to the 'phage' integrase family
GDHHKMLE_01355 2.09e-91 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GDHHKMLE_01356 8.43e-67 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GDHHKMLE_01357 3.89e-252 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GDHHKMLE_01358 4.42e-49 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GDHHKMLE_01359 0.0 - - - M - - - domain protein
GDHHKMLE_01360 0.0 - - - M - - - domain protein
GDHHKMLE_01361 3.63e-47 - 3.4.23.43 - - ko:K02236 - ko00000,ko00002,ko01000,ko02044 -
GDHHKMLE_01362 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDHHKMLE_01363 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDHHKMLE_01364 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GDHHKMLE_01365 2.5e-104 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GDHHKMLE_01372 1.15e-146 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
GDHHKMLE_01373 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
GDHHKMLE_01374 1.59e-213 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_01375 2.58e-176 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GDHHKMLE_01376 5.7e-112 ORF00048 - - - - - - -
GDHHKMLE_01377 4.59e-75 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
GDHHKMLE_01378 1.57e-136 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
GDHHKMLE_01379 1.94e-110 - - - K - - - GNAT family
GDHHKMLE_01380 4.44e-134 kptA - - J ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GDHHKMLE_01381 3.61e-55 - - - - - - - -
GDHHKMLE_01382 4.1e-307 citM - - C ko:K03300 - ko00000 Citrate transporter
GDHHKMLE_01383 1.76e-68 - - - - - - - -
GDHHKMLE_01384 2.5e-59 oadG - - I - - - Biotin-requiring enzyme
GDHHKMLE_01385 9.25e-250 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
GDHHKMLE_01386 3.26e-07 - - - - - - - -
GDHHKMLE_01387 3.01e-228 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GDHHKMLE_01388 3.41e-65 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
GDHHKMLE_01389 7.46e-201 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
GDHHKMLE_01390 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
GDHHKMLE_01391 3.38e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GDHHKMLE_01392 0.0 oadA 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Conserved carboxylase domain
GDHHKMLE_01393 4.14e-163 citR - - K - - - FCD
GDHHKMLE_01394 1.15e-198 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GDHHKMLE_01395 7.43e-97 - - - - - - - -
GDHHKMLE_01397 1.56e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
GDHHKMLE_01398 3.73e-283 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
GDHHKMLE_01399 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_01400 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_01401 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GDHHKMLE_01402 9.2e-210 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
GDHHKMLE_01403 1.44e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
GDHHKMLE_01404 4.07e-114 - - - S - - - ECF-type riboflavin transporter, S component
GDHHKMLE_01405 1.23e-185 CcmA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_01406 0.0 - - - - - - - -
GDHHKMLE_01407 1.99e-224 yicL - - EG - - - EamA-like transporter family
GDHHKMLE_01408 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
GDHHKMLE_01409 7.37e-140 - - - N - - - WxL domain surface cell wall-binding
GDHHKMLE_01410 4.64e-76 - - - - - - - -
GDHHKMLE_01411 4.91e-142 - - - S - - - WxL domain surface cell wall-binding
GDHHKMLE_01412 4.95e-173 degV - - S - - - Uncharacterised protein, DegV family COG1307
GDHHKMLE_01413 1.63e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
GDHHKMLE_01414 1.64e-192 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDHHKMLE_01415 3.34e-116 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
GDHHKMLE_01416 1.16e-155 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_01417 2.3e-276 - - - - - - - -
GDHHKMLE_01418 1.26e-87 - - - K - - - helix_turn_helix, mercury resistance
GDHHKMLE_01419 1.34e-63 - - - S - - - Protein of unknown function (DUF2568)
GDHHKMLE_01420 5.62e-293 - - - - - - - -
GDHHKMLE_01421 1.17e-174 - - - - - - - -
GDHHKMLE_01422 0.0 - - - D - - - Putative exonuclease SbcCD, C subunit
GDHHKMLE_01423 1.61e-166 - - - S - - - Protein of unknown function C-terminus (DUF2399)
GDHHKMLE_01424 3.43e-155 - - - K - - - Acetyltransferase (GNAT) domain
GDHHKMLE_01425 1.23e-57 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
GDHHKMLE_01426 2.15e-63 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
GDHHKMLE_01428 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
GDHHKMLE_01429 4.44e-90 - - - K - - - Cro/C1-type HTH DNA-binding domain
GDHHKMLE_01430 5.31e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GDHHKMLE_01431 4.11e-110 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GDHHKMLE_01432 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GDHHKMLE_01433 2.48e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GDHHKMLE_01434 2.45e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GDHHKMLE_01435 1.44e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GDHHKMLE_01436 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GDHHKMLE_01437 4.23e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GDHHKMLE_01438 3.84e-25 - - - S - - - Haloacid dehalogenase-like hydrolase
GDHHKMLE_01439 6.89e-110 - - - S - - - Haloacid dehalogenase-like hydrolase
GDHHKMLE_01440 4.64e-151 radC - - L ko:K03630 - ko00000 DNA repair protein
GDHHKMLE_01441 4.82e-229 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
GDHHKMLE_01442 1.88e-191 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GDHHKMLE_01443 8.66e-113 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
GDHHKMLE_01444 1.56e-147 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GDHHKMLE_01445 8.63e-182 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
GDHHKMLE_01446 1.32e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01447 3.29e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GDHHKMLE_01448 7.76e-192 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GDHHKMLE_01449 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GDHHKMLE_01450 1.68e-58 - - - - - - - -
GDHHKMLE_01451 1.61e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GDHHKMLE_01452 6.77e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GDHHKMLE_01453 1.6e-68 ftsL - - D - - - cell division protein FtsL
GDHHKMLE_01454 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GDHHKMLE_01455 1.33e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GDHHKMLE_01456 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GDHHKMLE_01457 4e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GDHHKMLE_01458 9.8e-199 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GDHHKMLE_01459 5.87e-311 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GDHHKMLE_01460 3.25e-291 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GDHHKMLE_01461 7.24e-102 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GDHHKMLE_01462 5.58e-60 ylmG - - S ko:K02221 - ko00000,ko02044 integral membrane protein
GDHHKMLE_01463 2.92e-186 ylmH - - S - - - S4 domain protein
GDHHKMLE_01464 1.4e-118 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA protein
GDHHKMLE_01465 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GDHHKMLE_01466 4.62e-48 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
GDHHKMLE_01467 1.4e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GDHHKMLE_01468 0.0 ydiC1 - - EGP - - - Major Facilitator
GDHHKMLE_01469 2.97e-269 yaaN - - P - - - Toxic anion resistance protein (TelA)
GDHHKMLE_01470 1.89e-149 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
GDHHKMLE_01471 2.49e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GDHHKMLE_01472 1.42e-39 - - - - - - - -
GDHHKMLE_01473 1.95e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GDHHKMLE_01474 1.62e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GDHHKMLE_01475 1.21e-75 XK27_04120 - - S - - - Putative amino acid metabolism
GDHHKMLE_01476 0.0 uvrA2 - - L - - - ABC transporter
GDHHKMLE_01477 7.08e-305 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GDHHKMLE_01479 3.85e-158 pgm6 - - G - - - phosphoglycerate mutase
GDHHKMLE_01480 1.62e-151 - - - S - - - repeat protein
GDHHKMLE_01481 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GDHHKMLE_01482 4.06e-312 - - - S - - - Sterol carrier protein domain
GDHHKMLE_01483 1.15e-232 ytlR - - I - - - Diacylglycerol kinase catalytic domain
GDHHKMLE_01484 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GDHHKMLE_01485 2.02e-43 ykzG - - S - - - Belongs to the UPF0356 family
GDHHKMLE_01486 2.6e-85 - - - - - - - -
GDHHKMLE_01487 1.73e-63 - - - - - - - -
GDHHKMLE_01488 4.82e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GDHHKMLE_01489 1.23e-127 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
GDHHKMLE_01491 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GDHHKMLE_01492 5.36e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GDHHKMLE_01493 9.2e-215 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_01494 1.91e-46 - - - S - - - Phospholipase_D-nuclease N-terminal
GDHHKMLE_01495 5.88e-257 - - - K - - - Helix-turn-helix XRE-family like proteins
GDHHKMLE_01496 1.99e-205 lysR5 - - K - - - LysR substrate binding domain
GDHHKMLE_01497 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
GDHHKMLE_01498 1.54e-162 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
GDHHKMLE_01499 2.51e-74 cadC5 - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
GDHHKMLE_01500 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
GDHHKMLE_01501 9.64e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GDHHKMLE_01502 1.33e-276 - - - - - - - -
GDHHKMLE_01503 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GDHHKMLE_01505 3.42e-178 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GDHHKMLE_01506 9.39e-80 - - - S - - - Protein of unknown function (DUF1093)
GDHHKMLE_01507 2.69e-79 - - - S - - - Domain of unknown function (DUF4828)
GDHHKMLE_01508 2.21e-226 mocA - - S - - - Oxidoreductase
GDHHKMLE_01509 4.41e-289 yfmL - - L - - - DEAD DEAH box helicase
GDHHKMLE_01510 7.9e-74 chbA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
GDHHKMLE_01511 4.49e-93 - - - S - - - Domain of unknown function (DUF3284)
GDHHKMLE_01513 1.04e-06 - - - - - - - -
GDHHKMLE_01514 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GDHHKMLE_01515 1.92e-304 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
GDHHKMLE_01516 9.92e-143 - - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_01517 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
GDHHKMLE_01518 1.61e-228 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GDHHKMLE_01519 1.24e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
GDHHKMLE_01520 4.05e-205 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GDHHKMLE_01521 2.05e-256 - - - M - - - Glycosyltransferase like family 2
GDHHKMLE_01523 1.02e-20 - - - - - - - -
GDHHKMLE_01524 3.26e-253 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
GDHHKMLE_01525 3.99e-157 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GDHHKMLE_01526 7.81e-262 - - - S - - - Bacterial low temperature requirement A protein (LtrA)
GDHHKMLE_01527 5.25e-61 - - - - - - - -
GDHHKMLE_01528 1.64e-262 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
GDHHKMLE_01529 1.59e-28 yhjA - - K - - - CsbD-like
GDHHKMLE_01531 1.5e-44 - - - - - - - -
GDHHKMLE_01532 1.27e-23 - - - - - - - -
GDHHKMLE_01533 2.45e-286 - - - EGP - - - Transmembrane secretion effector
GDHHKMLE_01534 1.15e-279 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GDHHKMLE_01535 5.43e-191 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GDHHKMLE_01537 3.64e-55 - - - - - - - -
GDHHKMLE_01538 1.09e-292 - - - S - - - Membrane
GDHHKMLE_01539 2.12e-187 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GDHHKMLE_01540 0.0 - - - M - - - Cna protein B-type domain
GDHHKMLE_01541 5.57e-305 - - - - - - - -
GDHHKMLE_01542 0.0 - - - M - - - domain protein
GDHHKMLE_01543 1.95e-81 yugI - - J ko:K07570 - ko00000 general stress protein
GDHHKMLE_01544 2.99e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GDHHKMLE_01545 1.11e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GDHHKMLE_01546 2.26e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
GDHHKMLE_01547 2.05e-147 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
GDHHKMLE_01548 6.43e-146 - - - S - - - Protein of unknown function (DUF1461)
GDHHKMLE_01549 1.34e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GDHHKMLE_01550 1.02e-150 yutD - - S - - - Protein of unknown function (DUF1027)
GDHHKMLE_01551 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GDHHKMLE_01552 4.29e-147 - - - S - - - Calcineurin-like phosphoesterase
GDHHKMLE_01553 2.69e-150 yibF - - S - - - overlaps another CDS with the same product name
GDHHKMLE_01554 4.19e-241 yibE - - S - - - overlaps another CDS with the same product name
GDHHKMLE_01555 1.66e-71 - - - - - - - -
GDHHKMLE_01556 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
GDHHKMLE_01557 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
GDHHKMLE_01558 5.87e-177 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GDHHKMLE_01559 6.14e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
GDHHKMLE_01560 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
GDHHKMLE_01562 1.87e-191 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
GDHHKMLE_01563 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01564 5.03e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_01565 9.71e-127 - - - K - - - transcriptional regulator
GDHHKMLE_01566 8.09e-193 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
GDHHKMLE_01567 6.33e-42 - - - - - - - -
GDHHKMLE_01570 1.38e-158 - - - S ko:K07090 - ko00000 membrane transporter protein
GDHHKMLE_01571 4.71e-131 - - - S - - - Protein of unknown function (DUF1211)
GDHHKMLE_01572 8.19e-212 - - - P - - - CorA-like Mg2+ transporter protein
GDHHKMLE_01573 3.84e-145 - - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_01575 3.92e-305 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GDHHKMLE_01576 5.98e-72 - - - - - - - -
GDHHKMLE_01578 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GDHHKMLE_01579 5.01e-140 - - - S - - - Membrane
GDHHKMLE_01580 9.75e-174 ypaC - - Q - - - Methyltransferase domain
GDHHKMLE_01581 0.0 - - - S - - - ABC transporter
GDHHKMLE_01582 1.32e-220 draG - - O - - - ADP-ribosylglycohydrolase
GDHHKMLE_01583 2.53e-139 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GDHHKMLE_01584 4.42e-54 - - - - - - - -
GDHHKMLE_01585 2.55e-173 - - - S - - - Protein of unknown function (DUF975)
GDHHKMLE_01586 2.32e-188 - - - M - - - Glycosyltransferase like family 2
GDHHKMLE_01587 7.68e-174 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
GDHHKMLE_01588 2.31e-101 - - - T - - - Sh3 type 3 domain protein
GDHHKMLE_01589 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GDHHKMLE_01590 1.39e-239 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GDHHKMLE_01591 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GDHHKMLE_01592 1.52e-205 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
GDHHKMLE_01593 2.09e-211 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
GDHHKMLE_01594 4.91e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
GDHHKMLE_01595 5.86e-167 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GDHHKMLE_01596 3.74e-75 - - - - - - - -
GDHHKMLE_01597 2.7e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
GDHHKMLE_01598 2.86e-108 uspA - - T - - - universal stress protein
GDHHKMLE_01599 6.74e-52 - - - - - - - -
GDHHKMLE_01600 5.56e-305 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GDHHKMLE_01601 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
GDHHKMLE_01602 1.41e-98 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
GDHHKMLE_01603 2.44e-142 yktB - - S - - - Belongs to the UPF0637 family
GDHHKMLE_01604 2.41e-157 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
GDHHKMLE_01605 9.32e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GDHHKMLE_01606 1.28e-155 - - - G - - - alpha-ribazole phosphatase activity
GDHHKMLE_01607 1.15e-196 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GDHHKMLE_01608 5.56e-217 - - - IQ - - - NAD dependent epimerase/dehydratase family
GDHHKMLE_01609 8.4e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GDHHKMLE_01610 2.05e-173 - - - F - - - deoxynucleoside kinase
GDHHKMLE_01611 8.16e-203 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
GDHHKMLE_01612 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GDHHKMLE_01613 2.67e-197 - - - T - - - GHKL domain
GDHHKMLE_01614 8.84e-120 ccpN - - K - - - Domain in cystathionine beta-synthase and other proteins.
GDHHKMLE_01615 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
GDHHKMLE_01616 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GDHHKMLE_01617 1.17e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GDHHKMLE_01618 1.75e-275 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GDHHKMLE_01619 2.2e-253 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GDHHKMLE_01620 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GDHHKMLE_01621 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GDHHKMLE_01622 5.93e-93 - - - S - - - Protein of unknown function (DUF805)
GDHHKMLE_01623 1.22e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
GDHHKMLE_01624 4.85e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTPase
GDHHKMLE_01625 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GDHHKMLE_01626 5.49e-261 yacL - - S - - - domain protein
GDHHKMLE_01627 4.87e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_01628 1.93e-27 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GDHHKMLE_01629 1.89e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GDHHKMLE_01630 0.0 - - - K - - - Mga helix-turn-helix domain
GDHHKMLE_01631 0.0 - - - K - - - Mga helix-turn-helix domain
GDHHKMLE_01632 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
GDHHKMLE_01634 2.4e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
GDHHKMLE_01635 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GDHHKMLE_01636 2.29e-125 - - - - - - - -
GDHHKMLE_01637 9.87e-127 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GDHHKMLE_01638 2.75e-245 - - - S - - - Protein of unknown function C-terminal (DUF3324)
GDHHKMLE_01639 8.02e-114 - - - - - - - -
GDHHKMLE_01640 2.38e-24 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GDHHKMLE_01641 1.03e-150 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GDHHKMLE_01642 2.86e-204 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GDHHKMLE_01643 2.08e-200 - - - I - - - alpha/beta hydrolase fold
GDHHKMLE_01644 1.86e-34 - - - - - - - -
GDHHKMLE_01645 4.56e-244 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GDHHKMLE_01646 2.12e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GDHHKMLE_01647 3.46e-136 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GDHHKMLE_01648 1.75e-167 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
GDHHKMLE_01649 1.17e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GDHHKMLE_01650 7.96e-309 ymfH - - S - - - Peptidase M16
GDHHKMLE_01651 7.4e-293 ymfF - - S - - - Peptidase M16 inactive domain protein
GDHHKMLE_01652 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GDHHKMLE_01653 4.04e-94 - - - S - - - Protein of unknown function (DUF1149)
GDHHKMLE_01654 3.75e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GDHHKMLE_01655 9.86e-200 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
GDHHKMLE_01656 1.94e-219 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GDHHKMLE_01657 4.94e-245 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GDHHKMLE_01658 4.12e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GDHHKMLE_01659 2e-82 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
GDHHKMLE_01660 2.3e-254 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GDHHKMLE_01661 6.56e-107 yvbK - - K - - - GNAT family
GDHHKMLE_01662 1.45e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
GDHHKMLE_01663 4.22e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GDHHKMLE_01664 1.26e-302 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GDHHKMLE_01665 6.67e-261 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GDHHKMLE_01666 9.74e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GDHHKMLE_01667 3.12e-135 - - - - - - - -
GDHHKMLE_01668 7.04e-136 - - - - - - - -
GDHHKMLE_01669 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GDHHKMLE_01670 4.55e-143 vanZ - - V - - - VanZ like family
GDHHKMLE_01671 3.72e-160 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
GDHHKMLE_01672 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GDHHKMLE_01673 3.93e-175 - - - S - - - Domain of unknown function DUF1829
GDHHKMLE_01674 1.44e-61 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
GDHHKMLE_01676 4.65e-195 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GDHHKMLE_01677 2.73e-71 - - - S - - - Pfam Transposase IS66
GDHHKMLE_01678 2.76e-294 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferases group 1
GDHHKMLE_01679 1.54e-220 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
GDHHKMLE_01680 5.68e-110 guaD - - FJ - - - MafB19-like deaminase
GDHHKMLE_01683 1.48e-103 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
GDHHKMLE_01684 1.53e-19 - - - - - - - -
GDHHKMLE_01685 1.8e-270 yttB - - EGP - - - Major Facilitator
GDHHKMLE_01686 4.36e-136 - - - S - - - Protein of unknown function (DUF1211)
GDHHKMLE_01687 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GDHHKMLE_01690 2.37e-162 pgm7 - - G - - - Phosphoglycerate mutase family
GDHHKMLE_01691 6.41e-155 - - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_01692 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_01693 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
GDHHKMLE_01694 4.13e-178 - - - S - - - NADPH-dependent FMN reductase
GDHHKMLE_01695 1.31e-208 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
GDHHKMLE_01696 1.3e-251 ampC - - V - - - Beta-lactamase
GDHHKMLE_01697 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
GDHHKMLE_01698 4.41e-143 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GDHHKMLE_01699 3.51e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GDHHKMLE_01700 6.65e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GDHHKMLE_01701 3.3e-236 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GDHHKMLE_01702 2.6e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GDHHKMLE_01703 3.05e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GDHHKMLE_01704 3.52e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GDHHKMLE_01705 2.57e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GDHHKMLE_01706 2.41e-78 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GDHHKMLE_01707 3.93e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GDHHKMLE_01708 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GDHHKMLE_01709 1.92e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GDHHKMLE_01710 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GDHHKMLE_01711 1.88e-91 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GDHHKMLE_01712 1.69e-41 - - - S - - - Protein of unknown function (DUF1146)
GDHHKMLE_01713 4.12e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
GDHHKMLE_01714 1.37e-26 - - - S - - - DNA-directed RNA polymerase subunit beta
GDHHKMLE_01715 1.14e-72 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
GDHHKMLE_01716 8.37e-42 - - - S - - - Protein of unknown function (DUF2969)
GDHHKMLE_01717 1.16e-284 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GDHHKMLE_01718 1.71e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
GDHHKMLE_01719 7.83e-200 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GDHHKMLE_01720 1.98e-61 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GDHHKMLE_01721 1.09e-185 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GDHHKMLE_01722 8.04e-192 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GDHHKMLE_01723 4.91e-242 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GDHHKMLE_01724 1.31e-149 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01725 4.85e-183 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
GDHHKMLE_01726 3.88e-243 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
GDHHKMLE_01727 6.63e-278 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GDHHKMLE_01728 4.06e-102 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GDHHKMLE_01729 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GDHHKMLE_01730 4.73e-31 - - - - - - - -
GDHHKMLE_01731 9.85e-88 - - - S - - - Protein of unknown function (DUF1694)
GDHHKMLE_01732 5.03e-230 - - - S - - - Protein of unknown function (DUF2785)
GDHHKMLE_01733 1.06e-149 yhfA - - S - - - HAD hydrolase, family IA, variant 3
GDHHKMLE_01734 1.41e-52 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
GDHHKMLE_01735 2.01e-119 M1-431 - - S - - - Protein of unknown function (DUF1706)
GDHHKMLE_01736 1.07e-84 - - - - - - - -
GDHHKMLE_01737 5.07e-258 yagE - - E - - - Amino acid permease
GDHHKMLE_01738 8.23e-218 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GDHHKMLE_01740 2.65e-217 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GDHHKMLE_01741 1.9e-232 - - - D ko:K06889 - ko00000 Alpha beta
GDHHKMLE_01742 4.35e-238 lipA - - I - - - Carboxylesterase family
GDHHKMLE_01743 1.38e-274 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
GDHHKMLE_01744 9.2e-101 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDHHKMLE_01745 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
GDHHKMLE_01746 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GDHHKMLE_01747 1.41e-167 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GDHHKMLE_01748 2.23e-191 - - - S - - - haloacid dehalogenase-like hydrolase
GDHHKMLE_01749 5.93e-59 - - - - - - - -
GDHHKMLE_01750 6.72e-19 - - - - - - - -
GDHHKMLE_01751 6.27e-67 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GDHHKMLE_01752 7.89e-66 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
GDHHKMLE_01753 2.36e-111 - - - - - - - -
GDHHKMLE_01754 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDHHKMLE_01755 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GDHHKMLE_01756 2.13e-172 - - - K ko:K03489 - ko00000,ko03000 UTRA
GDHHKMLE_01757 1.68e-103 - - - F - - - Nucleoside 2-deoxyribosyltransferase
GDHHKMLE_01758 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GDHHKMLE_01759 6.46e-83 - - - - - - - -
GDHHKMLE_01760 0.0 frvR - - K ko:K02538,ko:K03483,ko:K09685,ko:K18531 - ko00000,ko03000 transcriptional antiterminator
GDHHKMLE_01761 3.39e-183 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GDHHKMLE_01762 1.1e-134 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
GDHHKMLE_01763 3.19e-122 - - - - - - - -
GDHHKMLE_01764 4.61e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
GDHHKMLE_01765 6.6e-259 yueF - - S - - - AI-2E family transporter
GDHHKMLE_01766 3.96e-309 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
GDHHKMLE_01767 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GDHHKMLE_01768 9.39e-185 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GDHHKMLE_01769 2.47e-65 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
GDHHKMLE_01770 4.82e-109 - - - - - - - -
GDHHKMLE_01771 1.4e-189 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
GDHHKMLE_01772 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
GDHHKMLE_01773 7.75e-170 lutC - - S ko:K00782 - ko00000 LUD domain
GDHHKMLE_01774 4.1e-130 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GDHHKMLE_01775 3.51e-316 - - - EGP - - - Major Facilitator Superfamily
GDHHKMLE_01776 1.22e-93 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GDHHKMLE_01777 2.15e-269 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GDHHKMLE_01778 1.4e-208 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GDHHKMLE_01779 3.01e-227 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GDHHKMLE_01780 3.37e-249 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDHHKMLE_01781 3.67e-229 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDHHKMLE_01782 1.36e-23 gpm5 - - G - - - Phosphoglycerate mutase family
GDHHKMLE_01783 5.85e-107 gpm5 - - G - - - Phosphoglycerate mutase family
GDHHKMLE_01784 6.56e-64 - - - K - - - sequence-specific DNA binding
GDHHKMLE_01785 3.03e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GDHHKMLE_01786 1.42e-270 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GDHHKMLE_01787 7.49e-117 yrxA - - S ko:K07105 - ko00000 3H domain
GDHHKMLE_01788 8.03e-113 ytxH - - S - - - YtxH-like protein
GDHHKMLE_01789 2.12e-46 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GDHHKMLE_01790 6.86e-198 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GDHHKMLE_01791 1.33e-198 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
GDHHKMLE_01792 4.44e-110 ykuL - - S - - - CBS domain
GDHHKMLE_01793 1.9e-175 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
GDHHKMLE_01794 6.68e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
GDHHKMLE_01795 0.0 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GDHHKMLE_01796 1.66e-111 yslB - - S - - - Protein of unknown function (DUF2507)
GDHHKMLE_01797 8.29e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GDHHKMLE_01798 6.97e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GDHHKMLE_01799 9.86e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
GDHHKMLE_01800 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GDHHKMLE_01801 1.04e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
GDHHKMLE_01802 1.15e-151 - - - - - - - -
GDHHKMLE_01803 6.69e-61 - - - S - - - Enterocin A Immunity
GDHHKMLE_01804 7.46e-59 - - - S - - - Enterocin A Immunity
GDHHKMLE_01805 7.28e-41 spiA - - K - - - TRANSCRIPTIONal
GDHHKMLE_01806 0.0 - - - S - - - Putative threonine/serine exporter
GDHHKMLE_01808 9.15e-34 - - - - - - - -
GDHHKMLE_01809 3.8e-308 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
GDHHKMLE_01810 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDHHKMLE_01813 5.47e-174 - 2.7.13.3 - T ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
GDHHKMLE_01814 7.99e-184 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GDHHKMLE_01817 1.27e-15 - - - - - - - -
GDHHKMLE_01821 1.21e-182 - - - S - - - CAAX protease self-immunity
GDHHKMLE_01823 1.52e-72 - - - - - - - -
GDHHKMLE_01824 2.02e-126 - - - K ko:K18939 - ko00000,ko00002,ko03000 Bacterial regulatory proteins, tetR family
GDHHKMLE_01825 2.64e-316 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
GDHHKMLE_01826 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
GDHHKMLE_01827 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GDHHKMLE_01828 1.14e-80 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
GDHHKMLE_01829 0.0 - - - S - - - OPT oligopeptide transporter protein
GDHHKMLE_01830 8.73e-238 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GDHHKMLE_01831 1.45e-257 ald1 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
GDHHKMLE_01832 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
GDHHKMLE_01833 7.43e-144 - - - I - - - ABC-2 family transporter protein
GDHHKMLE_01834 1.52e-207 CcmA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_01835 6.81e-86 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
GDHHKMLE_01836 2.91e-277 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GDHHKMLE_01837 9.96e-212 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDHHKMLE_01838 4.42e-28 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
GDHHKMLE_01839 1.29e-186 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GDHHKMLE_01840 7.21e-129 - - - M - - - Sortase family
GDHHKMLE_01841 3.55e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
GDHHKMLE_01842 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GDHHKMLE_01843 3.24e-253 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GDHHKMLE_01844 2.7e-277 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
GDHHKMLE_01845 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
GDHHKMLE_01846 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GDHHKMLE_01847 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GDHHKMLE_01848 2.96e-311 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GDHHKMLE_01849 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GDHHKMLE_01850 9.45e-278 sstT - - U ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GDHHKMLE_01851 0.0 - - - E ko:K03294 - ko00000 Amino Acid
GDHHKMLE_01852 1.79e-187 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
GDHHKMLE_01853 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GDHHKMLE_01854 3.08e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
GDHHKMLE_01855 6.46e-32 - - - - - - - -
GDHHKMLE_01856 3.93e-99 - - - O - - - OsmC-like protein
GDHHKMLE_01857 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GDHHKMLE_01858 2.23e-143 ylbE - - GM - - - NAD(P)H-binding
GDHHKMLE_01859 1.11e-201 - - - S - - - Aldo/keto reductase family
GDHHKMLE_01860 2.74e-311 - - - - - - - -
GDHHKMLE_01861 2.41e-201 - - - V - - - ABC transporter
GDHHKMLE_01862 1.37e-108 - - - FG - - - adenosine 5'-monophosphoramidase activity
GDHHKMLE_01863 1.56e-311 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
GDHHKMLE_01864 5.5e-150 - - - J - - - HAD-hyrolase-like
GDHHKMLE_01865 1.59e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GDHHKMLE_01866 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GDHHKMLE_01867 4.52e-57 - - - - - - - -
GDHHKMLE_01868 3.5e-167 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GDHHKMLE_01869 6.73e-184 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GDHHKMLE_01870 1e-112 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
GDHHKMLE_01871 2.86e-140 - 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GDHHKMLE_01872 2.23e-50 - - - - - - - -
GDHHKMLE_01873 2.31e-87 - - - S - - - Protein of unknown function (DUF1093)
GDHHKMLE_01874 6.1e-27 - - - - - - - -
GDHHKMLE_01875 1.72e-64 - - - - - - - -
GDHHKMLE_01876 3.5e-112 - - - K - - - Acetyltransferase (GNAT) domain
GDHHKMLE_01879 1.23e-274 sip - - L - - - Belongs to the 'phage' integrase family
GDHHKMLE_01881 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
GDHHKMLE_01882 1.26e-211 arbZ - - I - - - Phosphate acyltransferases
GDHHKMLE_01883 2.7e-232 arbY - - M - - - family 8
GDHHKMLE_01884 8.22e-212 arbx - - M - - - Glycosyl transferase family 8
GDHHKMLE_01885 3.57e-189 arbV - - I - - - Phosphate acyltransferases
GDHHKMLE_01886 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GDHHKMLE_01887 1.41e-79 - - - - - - - -
GDHHKMLE_01888 4.35e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GDHHKMLE_01890 5.68e-24 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
GDHHKMLE_01891 9.48e-32 - - - - - - - -
GDHHKMLE_01893 1e-35 - - - - ko:K02245 - ko00000,ko00002,ko02044 -
GDHHKMLE_01894 3.36e-61 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
GDHHKMLE_01895 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
GDHHKMLE_01896 9.5e-39 - - - - - - - -
GDHHKMLE_01897 1.02e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
GDHHKMLE_01898 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GDHHKMLE_01899 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GDHHKMLE_01900 2.24e-134 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
GDHHKMLE_01901 5.36e-102 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GDHHKMLE_01902 3.92e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GDHHKMLE_01903 1.56e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GDHHKMLE_01904 8.48e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GDHHKMLE_01905 1.7e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GDHHKMLE_01906 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GDHHKMLE_01907 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GDHHKMLE_01908 4e-234 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GDHHKMLE_01909 1.6e-128 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GDHHKMLE_01910 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GDHHKMLE_01911 1.83e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GDHHKMLE_01912 1.17e-100 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
GDHHKMLE_01913 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
GDHHKMLE_01914 6.29e-141 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GDHHKMLE_01915 1.58e-262 - - - T ko:K19168 - ko00000,ko02048 His Kinase A (phosphoacceptor) domain
GDHHKMLE_01916 2.22e-159 rrp1 - - K ko:K02483 - ko00000,ko02022 response regulator
GDHHKMLE_01917 1.14e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_01918 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
GDHHKMLE_01919 1.86e-119 traP 1.14.99.57, 6.2.1.3 - S ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 heme oxygenase (decyclizing) activity
GDHHKMLE_01920 3.28e-176 yhfI - - S - - - Metallo-beta-lactamase superfamily
GDHHKMLE_01921 1.13e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GDHHKMLE_01922 1.44e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GDHHKMLE_01923 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
GDHHKMLE_01924 4.29e-226 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
GDHHKMLE_01925 1.16e-31 - - - - - - - -
GDHHKMLE_01926 1.97e-88 - - - - - - - -
GDHHKMLE_01928 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GDHHKMLE_01929 3.31e-98 argR1 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GDHHKMLE_01930 7.49e-198 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GDHHKMLE_01931 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GDHHKMLE_01932 2.96e-72 - - - S - - - Control of competence regulator ComK, YlbF/YmcA
GDHHKMLE_01933 2.41e-231 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
GDHHKMLE_01934 5.26e-205 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GDHHKMLE_01935 4.75e-80 - - - S - - - YtxH-like protein
GDHHKMLE_01936 1.67e-99 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
GDHHKMLE_01937 9.76e-172 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_01938 5.6e-273 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_01939 2.14e-187 ytmP - - M - - - Choline/ethanolamine kinase
GDHHKMLE_01940 2.33e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GDHHKMLE_01941 5.99e-06 - - - S - - - Small secreted protein
GDHHKMLE_01942 3.08e-72 ytpP - - CO - - - Thioredoxin
GDHHKMLE_01943 2.61e-148 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GDHHKMLE_01944 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GDHHKMLE_01945 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GDHHKMLE_01946 1.79e-155 ybhL - - S ko:K06890 - ko00000 Inhibitor of apoptosis-promoting Bax1
GDHHKMLE_01947 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GDHHKMLE_01948 1.85e-205 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GDHHKMLE_01949 2.71e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GDHHKMLE_01950 2.06e-103 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GDHHKMLE_01951 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
GDHHKMLE_01952 2.02e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GDHHKMLE_01954 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GDHHKMLE_01955 1.17e-130 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
GDHHKMLE_01956 5.3e-70 - - - - - - - -
GDHHKMLE_01957 1.56e-165 - - - S - - - SseB protein N-terminal domain
GDHHKMLE_01958 7.46e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GDHHKMLE_01959 1.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GDHHKMLE_01960 1.02e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GDHHKMLE_01961 1.6e-146 - - - - - - - -
GDHHKMLE_01962 6.35e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_01963 2.05e-189 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GDHHKMLE_01964 1.44e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01965 6.51e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_01966 6.58e-225 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
GDHHKMLE_01967 5.55e-139 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
GDHHKMLE_01968 2.17e-161 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GDHHKMLE_01969 3.55e-312 cps2E - - M - - - Bacterial sugar transferase
GDHHKMLE_01970 7.06e-117 - - - - - - - -
GDHHKMLE_01971 7.42e-253 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GDHHKMLE_01972 3.36e-199 ykoT - - M - - - Glycosyl transferase family 2
GDHHKMLE_01973 4.78e-144 - - - M - - - Acyltransferase family
GDHHKMLE_01974 3.8e-316 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GDHHKMLE_01975 3.97e-227 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
GDHHKMLE_01976 1.23e-153 yqgG - - S ko:K07507 - ko00000,ko02000 MgtC family
GDHHKMLE_01977 1.72e-116 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GDHHKMLE_01978 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
GDHHKMLE_01979 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
GDHHKMLE_01980 3.5e-143 ung2 - - L - - - Uracil-DNA glycosylase
GDHHKMLE_01981 4.49e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GDHHKMLE_01982 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
GDHHKMLE_01983 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GDHHKMLE_01984 2.19e-110 - - - M - - - Glycosyltransferase like family 2
GDHHKMLE_01985 5.35e-119 - - - S - - - endonuclease exonuclease phosphatase family protein
GDHHKMLE_01986 1.45e-175 XK27_08455 - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
GDHHKMLE_01987 1.56e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
GDHHKMLE_01988 1.67e-105 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
GDHHKMLE_01989 3.72e-210 - - - K - - - Helix-turn-helix domain, rpiR family
GDHHKMLE_01990 6.51e-194 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GDHHKMLE_01991 1.22e-246 - - - V - - - Beta-lactamase
GDHHKMLE_01992 5.95e-241 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GDHHKMLE_01993 1.19e-186 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
GDHHKMLE_01994 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GDHHKMLE_01995 4.47e-159 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GDHHKMLE_01996 1.96e-183 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GDHHKMLE_01997 1.14e-219 - - - S - - - EpsG family
GDHHKMLE_01998 1.81e-99 - - - D - - - Capsular exopolysaccharide family
GDHHKMLE_01999 2.95e-119 ywqC - - M ko:K16554 ko05111,map05111 ko00000,ko00001,ko02000 capsule polysaccharide biosynthetic process
GDHHKMLE_02000 1.02e-303 - - - S - - - polysaccharide biosynthetic process
GDHHKMLE_02001 4.4e-244 - - - M - - - Glycosyl transferases group 1
GDHHKMLE_02002 3.67e-127 tagF 2.7.8.12 - M ko:K09809,ko:K19046 - ko00000,ko01000,ko02048 Glycosyl transferase, family 2
GDHHKMLE_02003 2.44e-77 - - - S - - - Psort location CytoplasmicMembrane, score
GDHHKMLE_02004 5.1e-296 - - - S - - - Bacterial membrane protein, YfhO
GDHHKMLE_02005 0.0 - - - M - - - Glycosyl hydrolases family 25
GDHHKMLE_02006 4.74e-50 - - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
GDHHKMLE_02007 0.0 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
GDHHKMLE_02008 1.4e-60 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
GDHHKMLE_02009 1.68e-227 mhqA - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GDHHKMLE_02010 6.64e-39 - - - - - - - -
GDHHKMLE_02011 4.24e-134 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GDHHKMLE_02012 0.0 - - - - - - - -
GDHHKMLE_02014 5.5e-165 - - - S - - - WxL domain surface cell wall-binding
GDHHKMLE_02015 2.22e-113 - - - S - - - WxL domain surface cell wall-binding
GDHHKMLE_02016 2.43e-242 ynjC - - S - - - Cell surface protein
GDHHKMLE_02018 0.0 - - - L - - - Mga helix-turn-helix domain
GDHHKMLE_02019 1.25e-217 - - - S - - - Protein of unknown function (DUF805)
GDHHKMLE_02021 6.28e-43 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
GDHHKMLE_02022 1.71e-314 - - - U - - - AAA-like domain
GDHHKMLE_02023 2.54e-21 - - - U - - - PrgI family protein
GDHHKMLE_02024 4.06e-33 - - - - - - - -
GDHHKMLE_02025 1.74e-21 - - - - - - - -
GDHHKMLE_02026 1.39e-154 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
GDHHKMLE_02027 4.91e-11 - - - S - - - Protein of unknown function (DUF3801)
GDHHKMLE_02028 5.89e-56 - - - M - - - Domain of unknown function (DUF5011)
GDHHKMLE_02041 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GDHHKMLE_02042 5.31e-205 - - - - - - - -
GDHHKMLE_02043 2.2e-151 - - - - - - - -
GDHHKMLE_02044 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
GDHHKMLE_02045 3.49e-307 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GDHHKMLE_02046 2.22e-110 - - - - - - - -
GDHHKMLE_02047 0.0 strH 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Gram-positive signal peptide protein, YSIRK family
GDHHKMLE_02048 2.62e-248 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GDHHKMLE_02049 4.56e-47 XK27_04345 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
GDHHKMLE_02050 3.25e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GDHHKMLE_02051 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GDHHKMLE_02052 3.6e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GDHHKMLE_02053 1.79e-215 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GDHHKMLE_02054 1.43e-209 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GDHHKMLE_02055 8.44e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GDHHKMLE_02056 3.98e-29 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GDHHKMLE_02057 5.18e-88 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
GDHHKMLE_02058 3.27e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GDHHKMLE_02059 1.03e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GDHHKMLE_02060 6.78e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GDHHKMLE_02061 1.38e-84 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GDHHKMLE_02062 2.76e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GDHHKMLE_02063 9.62e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GDHHKMLE_02064 3e-69 - - - - - - - -
GDHHKMLE_02065 1.2e-75 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GDHHKMLE_02067 6.34e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GDHHKMLE_02068 2.45e-215 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GDHHKMLE_02069 1.51e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GDHHKMLE_02070 4.4e-116 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GDHHKMLE_02071 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GDHHKMLE_02072 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GDHHKMLE_02073 1.46e-240 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GDHHKMLE_02074 9.26e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GDHHKMLE_02075 8.13e-82 - - - - - - - -
GDHHKMLE_02077 2.83e-90 - - - L - - - NUDIX domain
GDHHKMLE_02078 4.24e-189 - - - EG - - - EamA-like transporter family
GDHHKMLE_02079 2.02e-308 YSH1 - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Metallo-beta-lactamase superfamily
GDHHKMLE_02080 2.66e-306 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GDHHKMLE_02081 1.1e-188 malF - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GDHHKMLE_02082 7.01e-213 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
GDHHKMLE_02083 6.22e-248 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
GDHHKMLE_02084 3.63e-136 - - - K ko:K06977 - ko00000 Acetyltransferase (GNAT) domain
GDHHKMLE_02085 7.57e-119 - - - - - - - -
GDHHKMLE_02086 4e-203 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
GDHHKMLE_02087 1.63e-163 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GDHHKMLE_02088 6.09e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GDHHKMLE_02089 4.52e-106 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
GDHHKMLE_02091 6.97e-209 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_02092 5.8e-146 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GDHHKMLE_02093 7.97e-41 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GDHHKMLE_02094 2.59e-97 - - - - - - - -
GDHHKMLE_02095 2.02e-270 - - - - - - - -
GDHHKMLE_02096 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GDHHKMLE_02097 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GDHHKMLE_02098 1.01e-230 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
GDHHKMLE_02099 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GDHHKMLE_02100 2.85e-209 - - - GM - - - NmrA-like family
GDHHKMLE_02101 3.95e-297 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
GDHHKMLE_02102 1.14e-182 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
GDHHKMLE_02103 8.74e-194 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GDHHKMLE_02104 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
GDHHKMLE_02105 3.23e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GDHHKMLE_02106 8.8e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GDHHKMLE_02107 6.98e-284 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GDHHKMLE_02108 2.37e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GDHHKMLE_02109 1.63e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
GDHHKMLE_02110 5.32e-219 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
GDHHKMLE_02111 1.38e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GDHHKMLE_02112 3.25e-225 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GDHHKMLE_02113 2.44e-99 - - - K - - - Winged helix DNA-binding domain
GDHHKMLE_02114 2.77e-94 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
GDHHKMLE_02115 2.44e-244 - - - E - - - Alpha/beta hydrolase family
GDHHKMLE_02116 1.08e-287 - - - C - - - Iron-containing alcohol dehydrogenase
GDHHKMLE_02117 3.32e-62 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
GDHHKMLE_02118 1.92e-88 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
GDHHKMLE_02119 5.76e-14 tcaA - - S ko:K21463 - ko00000 response to antibiotic
GDHHKMLE_02120 2.4e-214 - - - S - - - Putative esterase
GDHHKMLE_02121 5.01e-254 - - - - - - - -
GDHHKMLE_02122 1.72e-135 - - - K - - - Transcriptional regulator, MarR family
GDHHKMLE_02123 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GDHHKMLE_02124 8.02e-107 - - - F - - - NUDIX domain
GDHHKMLE_02125 3.85e-167 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GDHHKMLE_02126 4.74e-30 - - - - - - - -
GDHHKMLE_02127 8.98e-209 - - - S - - - zinc-ribbon domain
GDHHKMLE_02128 1.63e-259 pbpX - - V - - - Beta-lactamase
GDHHKMLE_02129 4.01e-240 ydbI - - K - - - AI-2E family transporter
GDHHKMLE_02130 4.31e-166 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GDHHKMLE_02131 1.16e-84 gtcA2 - - S - - - Teichoic acid glycosylation protein
GDHHKMLE_02132 8.29e-223 - - - I - - - Diacylglycerol kinase catalytic domain
GDHHKMLE_02133 0.0 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GDHHKMLE_02134 3.51e-216 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
GDHHKMLE_02135 5.82e-189 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
GDHHKMLE_02136 9.19e-285 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
GDHHKMLE_02137 3.99e-176 sfsA - - S ko:K06206 - ko00000 Belongs to the SfsA family
GDHHKMLE_02138 2.6e-96 usp1 - - T - - - Universal stress protein family
GDHHKMLE_02139 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
GDHHKMLE_02140 2.03e-191 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GDHHKMLE_02141 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
GDHHKMLE_02142 9.26e-290 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GDHHKMLE_02143 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GDHHKMLE_02144 2.16e-268 floL - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 SPFH domain / Band 7 family
GDHHKMLE_02145 1.32e-51 - - - - - - - -
GDHHKMLE_02146 1.75e-221 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
GDHHKMLE_02147 2.05e-225 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GDHHKMLE_02148 3.99e-278 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GDHHKMLE_02149 8.49e-66 - - - - - - - -
GDHHKMLE_02150 2.21e-164 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
GDHHKMLE_02151 4.48e-91 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
GDHHKMLE_02152 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GDHHKMLE_02154 0.0 bglB 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
GDHHKMLE_02155 3.42e-210 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
GDHHKMLE_02156 1.14e-210 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_02157 5.61e-207 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GDHHKMLE_02158 3.37e-180 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_02159 1.95e-221 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
GDHHKMLE_02160 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
GDHHKMLE_02161 5.05e-230 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
GDHHKMLE_02162 3.34e-45 - - - - - - - -
GDHHKMLE_02163 2.83e-238 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
GDHHKMLE_02164 7.69e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GDHHKMLE_02165 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GDHHKMLE_02166 4.84e-198 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GDHHKMLE_02167 3.31e-213 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
GDHHKMLE_02168 3.16e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GDHHKMLE_02169 0.0 pbpC - - M ko:K21467 - ko00000,ko01011 NTF2-like N-terminal transpeptidase domain
GDHHKMLE_02170 1.9e-297 - - - EGP - - - Major Facilitator
GDHHKMLE_02171 1.09e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GDHHKMLE_02172 5.85e-128 - - - - - - - -
GDHHKMLE_02173 1.38e-28 - - - - - - - -
GDHHKMLE_02174 6.93e-72 - - - S - - - Protein of unknown function (DUF1516)
GDHHKMLE_02176 6.55e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
GDHHKMLE_02177 2.81e-214 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 alcohol dehydrogenase
GDHHKMLE_02178 2.74e-112 - - - K - - - Transcriptional regulator
GDHHKMLE_02179 9.97e-59 - - - - - - - -
GDHHKMLE_02180 1.17e-245 ldhD3 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GDHHKMLE_02181 1e-116 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
GDHHKMLE_02182 4.33e-260 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GDHHKMLE_02183 2.67e-56 - - - - - - - -
GDHHKMLE_02184 1.7e-262 mccF - - V - - - LD-carboxypeptidase
GDHHKMLE_02185 2.23e-235 yveB - - I - - - PAP2 superfamily
GDHHKMLE_02186 2.25e-34 - - - S - - - Protein of unknown function (DUF2089)
GDHHKMLE_02187 7.78e-52 - - - - - - - -
GDHHKMLE_02188 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
GDHHKMLE_02189 1.03e-89 - - - C - - - nadph quinone reductase
GDHHKMLE_02190 1.06e-69 ybjQ - - S - - - Belongs to the UPF0145 family
GDHHKMLE_02191 6.65e-160 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
GDHHKMLE_02192 1.69e-185 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GDHHKMLE_02193 2.74e-210 - - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_02194 5.16e-190 - - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
GDHHKMLE_02195 1.2e-95 - - - K - - - LytTr DNA-binding domain
GDHHKMLE_02196 5.49e-78 - - - S - - - Protein of unknown function (DUF3021)
GDHHKMLE_02197 6.8e-239 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
GDHHKMLE_02198 1.29e-171 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
GDHHKMLE_02199 0.0 - - - S - - - Protein of unknown function (DUF3800)
GDHHKMLE_02200 9.04e-317 yifK - - E ko:K03293 - ko00000 Amino acid permease
GDHHKMLE_02201 1.34e-41 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GDHHKMLE_02202 8.8e-103 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GDHHKMLE_02203 7.2e-176 - - - S - - - Domain of unknown function (DUF4918)
GDHHKMLE_02204 1.4e-260 - - - - - - - -
GDHHKMLE_02206 0.0 - - - EGP - - - Major Facilitator
GDHHKMLE_02207 8.58e-139 - - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_02209 1.79e-157 - - - - - - - -
GDHHKMLE_02210 1.47e-255 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-type transport system involved in multi-copper enzyme maturation permease component
GDHHKMLE_02211 1.16e-194 - - - - - - - -
GDHHKMLE_02212 2.79e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GDHHKMLE_02214 2.45e-103 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
GDHHKMLE_02215 6.77e-71 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
GDHHKMLE_02216 2.35e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GDHHKMLE_02217 9.84e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GDHHKMLE_02218 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GDHHKMLE_02219 1.26e-75 - - - - - - - -
GDHHKMLE_02220 1.14e-106 - - - S - - - ASCH
GDHHKMLE_02221 1.32e-33 - - - - - - - -
GDHHKMLE_02222 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GDHHKMLE_02223 4.82e-63 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
GDHHKMLE_02224 8.3e-181 - - - V - - - ABC transporter transmembrane region
GDHHKMLE_02225 6.46e-15 - - - G - - - Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GDHHKMLE_02226 2.24e-119 - - - G - - - Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GDHHKMLE_02227 8.68e-21 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDHHKMLE_02228 1.03e-265 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDHHKMLE_02229 2.09e-211 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GDHHKMLE_02230 1.84e-55 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_02231 1.33e-77 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_02232 5.83e-178 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
GDHHKMLE_02233 9.65e-179 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
GDHHKMLE_02234 9.21e-85 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
GDHHKMLE_02235 8.8e-83 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
GDHHKMLE_02236 5.16e-270 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
GDHHKMLE_02237 7.2e-98 - - - S - - - Threonine/Serine exporter, ThrE
GDHHKMLE_02238 2.2e-176 - - - S - - - Putative threonine/serine exporter
GDHHKMLE_02239 1.23e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GDHHKMLE_02240 2.11e-273 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
GDHHKMLE_02241 4.85e-102 - - - S - - - NUDIX domain
GDHHKMLE_02243 6.4e-25 - - - - - - - -
GDHHKMLE_02244 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GDHHKMLE_02245 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GDHHKMLE_02247 3.5e-158 bmr3 - - EGP - - - Major Facilitator
GDHHKMLE_02248 1.65e-142 bmr3 - - EGP - - - Major Facilitator
GDHHKMLE_02249 4.15e-129 yobS - - K - - - Bacterial regulatory proteins, tetR family
GDHHKMLE_02250 0.0 - - - E - - - Amino acid permease
GDHHKMLE_02251 3.66e-188 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GDHHKMLE_02252 4.09e-136 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GDHHKMLE_02253 4.49e-145 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GDHHKMLE_02254 2.53e-107 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
GDHHKMLE_02255 3.15e-162 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GDHHKMLE_02256 7.3e-120 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
GDHHKMLE_02257 1.22e-307 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GDHHKMLE_02258 1.11e-84 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GDHHKMLE_02260 2.37e-44 - - - S ko:K03824 - ko00000,ko01000 Acetyltransferase (GNAT) family
GDHHKMLE_02261 5.7e-36 - - - - - - - -
GDHHKMLE_02262 5.54e-50 - - - - - - - -
GDHHKMLE_02263 5.46e-108 - - - C - - - Flavodoxin
GDHHKMLE_02264 9.42e-63 - - - - - - - -
GDHHKMLE_02265 5.12e-117 - - - - - - - -
GDHHKMLE_02266 1.47e-07 - - - - - - - -
GDHHKMLE_02267 6.45e-74 ywjH - - S - - - Protein of unknown function (DUF1634)
GDHHKMLE_02268 3.56e-177 yunE - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
GDHHKMLE_02269 1.04e-287 - - - S ko:K06872 - ko00000 TPM domain
GDHHKMLE_02270 6.18e-150 - - - - - - - -
GDHHKMLE_02271 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GDHHKMLE_02272 0.0 fnq20 - - S - - - FAD-NAD(P)-binding
GDHHKMLE_02275 8.47e-241 - - - K - - - DNA-binding helix-turn-helix protein
GDHHKMLE_02276 3.36e-77 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
GDHHKMLE_02277 7.46e-60 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
GDHHKMLE_02278 4.91e-55 - - - - - - - -
GDHHKMLE_02279 1.3e-241 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GDHHKMLE_02281 1.09e-70 - - - - - - - -
GDHHKMLE_02282 1.79e-104 - - - - - - - -
GDHHKMLE_02283 2.35e-266 XK27_05220 - - S - - - AI-2E family transporter
GDHHKMLE_02284 1.58e-33 - - - - - - - -
GDHHKMLE_02285 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GDHHKMLE_02286 1.79e-59 - - - - - - - -
GDHHKMLE_02287 8.47e-214 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
GDHHKMLE_02288 1.45e-116 - - - S - - - Flavin reductase like domain
GDHHKMLE_02289 2.22e-89 - - - - - - - -
GDHHKMLE_02290 6.3e-129 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GDHHKMLE_02291 1.7e-81 yeaO - - S - - - Protein of unknown function, DUF488
GDHHKMLE_02292 2.2e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GDHHKMLE_02293 2.41e-201 mleR - - K - - - LysR family
GDHHKMLE_02294 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
GDHHKMLE_02295 3.58e-217 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
GDHHKMLE_02296 8.23e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GDHHKMLE_02297 1.54e-111 - - - C - - - FMN binding
GDHHKMLE_02298 2.19e-222 - - - K ko:K20373,ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
GDHHKMLE_02299 0.0 - - - V - - - ABC transporter transmembrane region
GDHHKMLE_02300 0.0 pepF - - E - - - Oligopeptidase F
GDHHKMLE_02301 3.86e-78 - - - - - - - -
GDHHKMLE_02302 3.81e-170 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GDHHKMLE_02303 4.06e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
GDHHKMLE_02304 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
GDHHKMLE_02305 7.43e-229 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 carboxylic ester hydrolase activity
GDHHKMLE_02306 1.69e-58 - - - - - - - -
GDHHKMLE_02307 1.64e-120 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GDHHKMLE_02308 2.29e-255 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GDHHKMLE_02309 1.24e-155 XK27_05175 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
GDHHKMLE_02310 9.12e-101 - - - K - - - Transcriptional regulator
GDHHKMLE_02311 9.78e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
GDHHKMLE_02312 3.83e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
GDHHKMLE_02313 2.52e-199 dkgB - - S - - - reductase
GDHHKMLE_02314 1.59e-199 - - - - - - - -
GDHHKMLE_02315 9.79e-196 - - - S - - - Alpha beta hydrolase
GDHHKMLE_02316 5.24e-150 yviA - - S - - - Protein of unknown function (DUF421)
GDHHKMLE_02317 3.69e-96 - - - S - - - Protein of unknown function (DUF3290)
GDHHKMLE_02318 1.89e-269 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GDHHKMLE_02319 2.8e-111 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GDHHKMLE_02320 1.3e-136 yjbF - - S - - - SNARE associated Golgi protein
GDHHKMLE_02321 2.95e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GDHHKMLE_02322 9.17e-241 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GDHHKMLE_02323 7.52e-263 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GDHHKMLE_02324 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GDHHKMLE_02325 1.83e-87 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GDHHKMLE_02326 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GDHHKMLE_02327 2.06e-150 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
GDHHKMLE_02328 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GDHHKMLE_02329 1.99e-261 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GDHHKMLE_02330 1.13e-307 ytoI - - K - - - DRTGG domain
GDHHKMLE_02331 2.49e-228 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GDHHKMLE_02332 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GDHHKMLE_02333 1.27e-222 - - - - - - - -
GDHHKMLE_02334 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GDHHKMLE_02336 4.89e-58 yrzL - - S - - - Belongs to the UPF0297 family
GDHHKMLE_02337 2.67e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GDHHKMLE_02338 1.3e-69 yrzB - - S - - - Belongs to the UPF0473 family
GDHHKMLE_02339 6.72e-47 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GDHHKMLE_02340 1.89e-119 cvpA - - S - - - Colicin V production protein
GDHHKMLE_02341 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GDHHKMLE_02342 3.64e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GDHHKMLE_02343 0.0 - - - S - - - Bacterial membrane protein YfhO
GDHHKMLE_02344 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
GDHHKMLE_02345 1e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GDHHKMLE_02346 1.22e-132 - - - - - - - -
GDHHKMLE_02347 8.49e-217 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
GDHHKMLE_02348 5.12e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
GDHHKMLE_02350 0.000235 - - - S - - - Ribbon-helix-helix protein, copG family
GDHHKMLE_02352 1.52e-282 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
GDHHKMLE_02354 0.0 - - - L - - - Protein of unknown function (DUF3991)
GDHHKMLE_02355 2.05e-86 - - - - - - - -
GDHHKMLE_02356 4.95e-23 - - - - - - - -
GDHHKMLE_02357 1.99e-89 - - - - - - - -
GDHHKMLE_02359 2.09e-95 - - - - - - - -
GDHHKMLE_02361 1.96e-53 - - - - - - - -
GDHHKMLE_02362 2.48e-165 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_02363 1.89e-189 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GDHHKMLE_02364 5.27e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
GDHHKMLE_02365 4.67e-155 rcfB - - K - - - Crp-like helix-turn-helix domain
GDHHKMLE_02366 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
GDHHKMLE_02367 6.12e-157 larB - - S ko:K06898 - ko00000 AIR carboxylase
GDHHKMLE_02368 6.2e-175 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GDHHKMLE_02369 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GDHHKMLE_02370 3.03e-192 larE - - S ko:K06864 - ko00000 NAD synthase
GDHHKMLE_02371 2.88e-66 - - - J - - - Methyltransferase domain
GDHHKMLE_02372 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GDHHKMLE_02374 1.98e-148 alkD - - L - - - DNA alkylation repair enzyme
GDHHKMLE_02375 1.45e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GDHHKMLE_02376 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GDHHKMLE_02377 1.43e-220 ykoT - - M - - - Glycosyl transferase family 2
GDHHKMLE_02378 5.61e-159 yhgE - - V ko:K01421 - ko00000 domain protein
GDHHKMLE_02379 2.84e-64 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GDHHKMLE_02380 1.37e-56 - - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDHHKMLE_02381 3.55e-174 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
GDHHKMLE_02382 2.74e-203 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
GDHHKMLE_02383 1.07e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GDHHKMLE_02384 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GDHHKMLE_02385 1.1e-76 - - - - - - - -
GDHHKMLE_02388 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GDHHKMLE_02389 2.57e-252 ysdE - - P - - - Citrate transporter
GDHHKMLE_02390 8.1e-89 - - - - - - - -
GDHHKMLE_02391 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
GDHHKMLE_02392 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GDHHKMLE_02393 8.92e-105 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GDHHKMLE_02394 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GDHHKMLE_02395 8.83e-57 ykuJ - - S - - - Protein of unknown function (DUF1797)
GDHHKMLE_02396 2.32e-279 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GDHHKMLE_02398 2.51e-217 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GDHHKMLE_02399 3.25e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GDHHKMLE_02400 1.09e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GDHHKMLE_02401 6.7e-128 dpsB - - P - - - Belongs to the Dps family
GDHHKMLE_02402 3.61e-46 copZ - - P - - - Heavy-metal-associated domain
GDHHKMLE_02403 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
GDHHKMLE_02405 5.74e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_02406 2.28e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_02407 3.55e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GDHHKMLE_02408 5.58e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GDHHKMLE_02409 2.33e-208 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GDHHKMLE_02410 2.1e-27 - - - - - - - -
GDHHKMLE_02414 4.89e-156 - - - - - - - -
GDHHKMLE_02417 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GDHHKMLE_02418 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GDHHKMLE_02419 1.18e-161 treR - - K ko:K03486 - ko00000,ko03000 UTRA
GDHHKMLE_02420 9.04e-102 - - - S - - - Putative transposase
GDHHKMLE_02421 2.12e-86 - - - S - - - Transposase zinc-binding domain
GDHHKMLE_02422 4.7e-283 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
GDHHKMLE_02423 4.32e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
GDHHKMLE_02424 7.09e-181 yycI - - S - - - YycH protein
GDHHKMLE_02425 0.0 yycH - - S - - - YycH protein
GDHHKMLE_02426 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDHHKMLE_02427 3.03e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GDHHKMLE_02428 1.44e-155 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha/beta hydrolase family
GDHHKMLE_02429 0.0 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GDHHKMLE_02430 2.69e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GDHHKMLE_02431 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
GDHHKMLE_02432 1.13e-271 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GDHHKMLE_02433 1.06e-95 - - - S - - - Domain of unknown function (DUF3284)
GDHHKMLE_02434 1.76e-298 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDHHKMLE_02435 5.66e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
GDHHKMLE_02436 5.86e-68 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GDHHKMLE_02437 8.36e-72 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
GDHHKMLE_02438 4.3e-139 yokL3 - - J - - - Acetyltransferase (GNAT) domain
GDHHKMLE_02439 1.51e-109 - - - F - - - NUDIX domain
GDHHKMLE_02440 2.15e-116 - - - S - - - AAA domain
GDHHKMLE_02441 3.32e-148 ycaC - - Q - - - Isochorismatase family
GDHHKMLE_02442 0.0 - - - EGP - - - Major Facilitator Superfamily
GDHHKMLE_02443 5.38e-272 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
GDHHKMLE_02444 2.11e-220 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
GDHHKMLE_02445 1.08e-84 manO - - S - - - Domain of unknown function (DUF956)
GDHHKMLE_02446 1.73e-216 manN - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
GDHHKMLE_02447 3.69e-170 manM - - G ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
GDHHKMLE_02448 1.97e-228 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
GDHHKMLE_02449 2.14e-237 - - - EGP - - - Major facilitator Superfamily
GDHHKMLE_02450 3.17e-27 - - - EGP - - - Major facilitator Superfamily
GDHHKMLE_02451 3.46e-148 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
GDHHKMLE_02452 6.56e-190 - - - K - - - Helix-turn-helix XRE-family like proteins
GDHHKMLE_02453 1.77e-203 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
GDHHKMLE_02455 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GDHHKMLE_02456 3.81e-172 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_02457 4.51e-41 - - - - - - - -
GDHHKMLE_02458 1.21e-304 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GDHHKMLE_02459 1.33e-166 - - - S - - - Protein of unknown function (DUF975)
GDHHKMLE_02460 5.96e-53 - - - S - - - Iron-sulphur cluster biosynthesis
GDHHKMLE_02461 8.12e-69 - - - - - - - -
GDHHKMLE_02462 2.49e-105 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
GDHHKMLE_02463 0.0 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
GDHHKMLE_02464 1.75e-182 - - - S - - - AAA ATPase domain
GDHHKMLE_02465 7.92e-215 - - - G - - - Phosphotransferase enzyme family
GDHHKMLE_02466 1.09e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_02467 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_02468 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDHHKMLE_02469 9.37e-129 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GDHHKMLE_02470 7.75e-138 - - - S ko:K06384 - ko00000 Stage II sporulation protein M
GDHHKMLE_02471 3.01e-181 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
GDHHKMLE_02472 3.05e-235 - - - S - - - Protein of unknown function DUF58
GDHHKMLE_02473 1.7e-145 yebA - - E - - - Transglutaminase/protease-like homologues
GDHHKMLE_02474 8.78e-269 yebA - - E - - - Transglutaminase/protease-like homologues
GDHHKMLE_02475 2.11e-273 - - - M - - - Glycosyl transferases group 1
GDHHKMLE_02476 6.35e-125 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
GDHHKMLE_02477 1.75e-185 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
GDHHKMLE_02478 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
GDHHKMLE_02479 2.77e-145 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
GDHHKMLE_02480 4.25e-61 yjdF3 - - S - - - Protein of unknown function (DUF2992)
GDHHKMLE_02481 3.49e-270 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
GDHHKMLE_02482 2.19e-291 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 2-hydroxycarboxylate transporter family
GDHHKMLE_02483 2.32e-235 dpiB 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
GDHHKMLE_02484 9.5e-82 dpiB 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
GDHHKMLE_02485 1.81e-156 malR - - KT ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
GDHHKMLE_02486 3.22e-39 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
GDHHKMLE_02487 4.81e-77 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
GDHHKMLE_02488 3.47e-214 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
GDHHKMLE_02491 1.41e-201 - - - S - - - Calcineurin-like phosphoesterase
GDHHKMLE_02492 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
GDHHKMLE_02493 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GDHHKMLE_02494 1.71e-87 - - - - - - - -
GDHHKMLE_02495 6.13e-100 - - - S - - - function, without similarity to other proteins
GDHHKMLE_02496 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
GDHHKMLE_02497 1.94e-86 spx2 - - P ko:K16509 - ko00000 ArsC family
GDHHKMLE_02498 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
GDHHKMLE_02499 1.34e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
GDHHKMLE_02500 2.11e-196 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GDHHKMLE_02501 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
GDHHKMLE_02502 1.73e-155 - 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GDHHKMLE_02503 7.54e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDHHKMLE_02504 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
GDHHKMLE_02505 2.55e-288 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GDHHKMLE_02506 4.62e-72 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GDHHKMLE_02507 7.78e-281 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GDHHKMLE_02508 4.24e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GDHHKMLE_02509 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GDHHKMLE_02510 4.15e-219 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GDHHKMLE_02511 4.99e-253 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GDHHKMLE_02513 1.32e-221 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GDHHKMLE_02514 3.13e-312 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GDHHKMLE_02515 6.28e-189 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GDHHKMLE_02516 1.41e-89 - - - K - - - Acetyltransferase (GNAT) domain
GDHHKMLE_02517 7.28e-144 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
GDHHKMLE_02518 9.35e-15 - - - - - - - -
GDHHKMLE_02519 1.12e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
GDHHKMLE_02521 0.0 - - - G - - - MFS/sugar transport protein
GDHHKMLE_02522 1.03e-289 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
GDHHKMLE_02523 1.35e-75 - - - - - - - -
GDHHKMLE_02524 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
GDHHKMLE_02525 1.8e-24 - - - S - - - Virus attachment protein p12 family
GDHHKMLE_02526 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
GDHHKMLE_02527 8.79e-135 - - - - - - - -
GDHHKMLE_02528 0.0 cadA - - P - - - P-type ATPase
GDHHKMLE_02529 1.22e-97 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GDHHKMLE_02530 2.35e-92 - - - S - - - Iron-sulphur cluster biosynthesis
GDHHKMLE_02531 1.98e-283 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
GDHHKMLE_02532 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GDHHKMLE_02533 2.36e-167 rpl - - K - - - Helix-turn-helix domain, rpiR family
GDHHKMLE_02534 2.57e-221 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
GDHHKMLE_02535 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GDHHKMLE_02536 2.37e-111 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
GDHHKMLE_02537 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
GDHHKMLE_02538 5.4e-69 - - - S - - - Phage head-tail joining protein
GDHHKMLE_02541 5.44e-104 terS - - L - - - Phage terminase, small subunit
GDHHKMLE_02542 6.95e-212 terL - - S - - - overlaps another CDS with the same product name
GDHHKMLE_02543 3.57e-144 is18 - - L - - - Integrase core domain
GDHHKMLE_02544 8.83e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GDHHKMLE_02545 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GDHHKMLE_02546 8.72e-52 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
GDHHKMLE_02547 0.0 - - - S - - - Mga helix-turn-helix domain
GDHHKMLE_02548 2.23e-62 - - - - - - - -
GDHHKMLE_02549 7.95e-317 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GDHHKMLE_02550 1.98e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GDHHKMLE_02551 1.11e-299 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
GDHHKMLE_02552 3.54e-103 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GDHHKMLE_02553 6.55e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GDHHKMLE_02554 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GDHHKMLE_02555 1.01e-237 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GDHHKMLE_02556 1.28e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 ABC transporter
GDHHKMLE_02558 1.29e-257 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
GDHHKMLE_02559 1.83e-168 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GDHHKMLE_02560 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDHHKMLE_02561 3.54e-196 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GDHHKMLE_02562 4.48e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GDHHKMLE_02563 1.06e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GDHHKMLE_02564 1.57e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GDHHKMLE_02565 3.54e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GDHHKMLE_02566 3.82e-156 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GDHHKMLE_02567 0.0 yvlB - - S - - - Putative adhesin
GDHHKMLE_02568 7.43e-50 - - - - - - - -
GDHHKMLE_02569 3.07e-50 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
GDHHKMLE_02570 8.27e-223 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GDHHKMLE_02571 7.94e-202 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GDHHKMLE_02572 6.03e-248 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GDHHKMLE_02573 1.43e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GDHHKMLE_02574 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GDHHKMLE_02575 2.02e-146 - - - T - - - Transcriptional regulatory protein, C terminal
GDHHKMLE_02576 3.22e-177 - - - T - - - His Kinase A (phosphoacceptor) domain
GDHHKMLE_02577 1e-65 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_02578 1.01e-53 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GDHHKMLE_02579 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GDHHKMLE_02580 1.99e-153 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
GDHHKMLE_02581 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GDHHKMLE_02582 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GDHHKMLE_02583 2.98e-110 - - - S - - - Short repeat of unknown function (DUF308)
GDHHKMLE_02584 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GDHHKMLE_02585 2.99e-248 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GDHHKMLE_02586 3.92e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GDHHKMLE_02587 7.84e-106 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
GDHHKMLE_02588 3.45e-131 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GDHHKMLE_02591 7.84e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
GDHHKMLE_02592 2.1e-247 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GDHHKMLE_02593 2.16e-282 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GDHHKMLE_02594 2.69e-178 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GDHHKMLE_02595 2.05e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GDHHKMLE_02596 1.49e-292 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
GDHHKMLE_02597 1.74e-59 - - - - - - - -
GDHHKMLE_02598 0.0 eriC - - P ko:K03281 - ko00000 chloride
GDHHKMLE_02599 5.04e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GDHHKMLE_02600 4.01e-181 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
GDHHKMLE_02601 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GDHHKMLE_02602 4.47e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GDHHKMLE_02603 1.09e-226 yvdE - - K - - - helix_turn _helix lactose operon repressor
GDHHKMLE_02604 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
GDHHKMLE_02605 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)