Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
EDGOKLHD_00001	8.95e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EDGOKLHD_00002	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EDGOKLHD_00003	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
EDGOKLHD_00004	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EDGOKLHD_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EDGOKLHD_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EDGOKLHD_00007	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
EDGOKLHD_00008	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EDGOKLHD_00009	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EDGOKLHD_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
EDGOKLHD_00011	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
EDGOKLHD_00012	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
EDGOKLHD_00013	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_00014	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EDGOKLHD_00015	3.25e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EDGOKLHD_00016	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
EDGOKLHD_00018	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EDGOKLHD_00019	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EDGOKLHD_00020	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
EDGOKLHD_00021	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
EDGOKLHD_00022	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EDGOKLHD_00023	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
EDGOKLHD_00025	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
EDGOKLHD_00026	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
EDGOKLHD_00027	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
EDGOKLHD_00028	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
EDGOKLHD_00029	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
EDGOKLHD_00030	2.54e-50	-	-	-	-	-	-	-	-
EDGOKLHD_00031	4.93e-291	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EDGOKLHD_00032	2.21e-157	-	-	-	K	-	-	-	sequence-specific DNA binding
EDGOKLHD_00034	3.96e-13	-	-	-	-	-	-	-	-
EDGOKLHD_00035	1.07e-39	-	-	-	-	-	-	-	-
EDGOKLHD_00036	6.55e-180	-	-	-	L	-	-	-	DNA replication protein
EDGOKLHD_00037	1.09e-63	-	-	-	S	-	-	-	Phage plasmid primase P4 family
EDGOKLHD_00039	6.01e-33	-	-	-	-	-	-	-	-
EDGOKLHD_00040	7.08e-66	-	-	-	S	-	-	-	Head-tail joining protein
EDGOKLHD_00041	4.46e-90	-	-	-	L	-	-	-	HNH endonuclease
EDGOKLHD_00042	7.73e-109	-	-	-	L	-	-	-	overlaps another CDS with the same product name
EDGOKLHD_00043	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
EDGOKLHD_00044	0.000495	-	-	-	-	-	-	-	-
EDGOKLHD_00045	1.06e-260	-	-	-	S	-	-	-	Phage portal protein
EDGOKLHD_00046	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
EDGOKLHD_00047	6.85e-55	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
EDGOKLHD_00049	6.55e-07	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
EDGOKLHD_00052	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
EDGOKLHD_00053	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EDGOKLHD_00054	5.04e-313	yycH	-	-	S	-	-	-	YycH protein
EDGOKLHD_00055	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
EDGOKLHD_00056	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
EDGOKLHD_00057	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
EDGOKLHD_00058	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EDGOKLHD_00059	2e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_00060	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
EDGOKLHD_00061	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
EDGOKLHD_00062	2.24e-155	pnb	-	-	C	-	-	-	nitroreductase
EDGOKLHD_00063	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
EDGOKLHD_00064	2.14e-148	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
EDGOKLHD_00065	0.0	-	-	-	C	-	-	-	FMN_bind
EDGOKLHD_00066	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
EDGOKLHD_00067	3.43e-203	-	-	-	K	-	-	-	LysR family
EDGOKLHD_00068	1.69e-93	-	-	-	C	-	-	-	FMN binding
EDGOKLHD_00069	1.82e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EDGOKLHD_00070	3.34e-210	-	-	-	S	-	-	-	KR domain
EDGOKLHD_00071	9.51e-203	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
EDGOKLHD_00072	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
EDGOKLHD_00073	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
EDGOKLHD_00074	2.22e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
EDGOKLHD_00075	2.28e-250	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EDGOKLHD_00076	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
EDGOKLHD_00077	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
EDGOKLHD_00078	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
EDGOKLHD_00079	1.65e-106	-	-	-	S	-	-	-	ASCH
EDGOKLHD_00080	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
EDGOKLHD_00081	1.88e-216	-	-	-	K	-	-	-	WYL domain
EDGOKLHD_00082	6.65e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EDGOKLHD_00083	0.0	fusA1	-	-	J	-	-	-	elongation factor G
EDGOKLHD_00084	3.66e-59	-	-	-	S	-	-	-	Protein of unknown function
EDGOKLHD_00085	2.84e-81	-	-	-	S	-	-	-	Protein of unknown function
EDGOKLHD_00086	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
EDGOKLHD_00087	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
EDGOKLHD_00088	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
EDGOKLHD_00089	3.42e-234	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
EDGOKLHD_00090	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EDGOKLHD_00091	6.97e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
EDGOKLHD_00092	3.5e-217	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
EDGOKLHD_00093	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
EDGOKLHD_00094	2.38e-99	-	-	-	-	-	-	-	-
EDGOKLHD_00095	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_00096	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
EDGOKLHD_00097	5.9e-181	-	-	-	-	-	-	-	-
EDGOKLHD_00098	4.07e-05	-	-	-	-	-	-	-	-
EDGOKLHD_00099	2.92e-186	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
EDGOKLHD_00100	1.67e-54	-	-	-	-	-	-	-	-
EDGOKLHD_00101	7.41e-167	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_00102	8.38e-193	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
EDGOKLHD_00103	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
EDGOKLHD_00104	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
EDGOKLHD_00105	4.57e-305	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
EDGOKLHD_00106	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
EDGOKLHD_00107	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EDGOKLHD_00108	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
EDGOKLHD_00109	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EDGOKLHD_00110	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
EDGOKLHD_00111	4.79e-225	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
EDGOKLHD_00113	2.27e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EDGOKLHD_00114	9.72e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
EDGOKLHD_00115	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EDGOKLHD_00116	9.14e-265	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
EDGOKLHD_00117	7.45e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
EDGOKLHD_00118	0.0	-	-	-	L	-	-	-	HIRAN domain
EDGOKLHD_00119	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
EDGOKLHD_00120	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
EDGOKLHD_00121	8.96e-160	-	-	-	-	-	-	-	-
EDGOKLHD_00122	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
EDGOKLHD_00123	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
EDGOKLHD_00124	1.29e-181	-	-	-	F	-	-	-	Phosphorylase superfamily
EDGOKLHD_00125	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
EDGOKLHD_00126	5.13e-144	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
EDGOKLHD_00127	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_00128	2.31e-95	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
EDGOKLHD_00129	2.14e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
EDGOKLHD_00130	4.14e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
EDGOKLHD_00131	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
EDGOKLHD_00132	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EDGOKLHD_00133	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
EDGOKLHD_00135	2.16e-204	morA	-	-	S	-	-	-	reductase
EDGOKLHD_00136	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
EDGOKLHD_00137	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
EDGOKLHD_00138	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
EDGOKLHD_00139	4.03e-132	-	-	-	-	-	-	-	-
EDGOKLHD_00140	0.0	-	-	-	-	-	-	-	-
EDGOKLHD_00141	1.86e-267	-	-	-	C	-	-	-	Oxidoreductase
EDGOKLHD_00142	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
EDGOKLHD_00143	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_00144	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
EDGOKLHD_00145	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
EDGOKLHD_00146	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
EDGOKLHD_00147	7.71e-183	-	-	-	-	-	-	-	-
EDGOKLHD_00148	5.24e-190	-	-	-	-	-	-	-	-
EDGOKLHD_00149	3.37e-115	-	-	-	-	-	-	-	-
EDGOKLHD_00150	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
EDGOKLHD_00151	1.04e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_00152	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
EDGOKLHD_00153	9.77e-152	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
EDGOKLHD_00154	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
EDGOKLHD_00155	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
EDGOKLHD_00157	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_00158	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
EDGOKLHD_00159	9.52e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
EDGOKLHD_00160	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
EDGOKLHD_00161	2.76e-74	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
EDGOKLHD_00162	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EDGOKLHD_00163	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
EDGOKLHD_00164	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
EDGOKLHD_00165	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
EDGOKLHD_00166	4.69e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
EDGOKLHD_00167	2.16e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EDGOKLHD_00168	2.33e-205	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_00169	1.75e-191	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
EDGOKLHD_00170	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
EDGOKLHD_00171	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EDGOKLHD_00172	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
EDGOKLHD_00173	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
EDGOKLHD_00174	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
EDGOKLHD_00175	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
EDGOKLHD_00176	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EDGOKLHD_00177	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
EDGOKLHD_00178	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
EDGOKLHD_00179	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
EDGOKLHD_00180	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
EDGOKLHD_00181	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
EDGOKLHD_00182	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
EDGOKLHD_00183	5.99e-213	mleR	-	-	K	-	-	-	LysR substrate binding domain
EDGOKLHD_00184	0.0	-	-	-	M	-	-	-	domain protein
EDGOKLHD_00186	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
EDGOKLHD_00187	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
EDGOKLHD_00188	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
EDGOKLHD_00189	1.31e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
EDGOKLHD_00190	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EDGOKLHD_00191	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EDGOKLHD_00192	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
EDGOKLHD_00193	1.01e-228	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
EDGOKLHD_00194	6.33e-46	-	-	-	-	-	-	-	-
EDGOKLHD_00195	4.69e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
EDGOKLHD_00196	6.21e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
EDGOKLHD_00197	2.6e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EDGOKLHD_00198	3.81e-18	-	-	-	-	-	-	-	-
EDGOKLHD_00199	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EDGOKLHD_00200	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EDGOKLHD_00201	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
EDGOKLHD_00202	6.11e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
EDGOKLHD_00203	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EDGOKLHD_00204	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
EDGOKLHD_00205	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
EDGOKLHD_00206	5.3e-202	dkgB	-	-	S	-	-	-	reductase
EDGOKLHD_00207	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EDGOKLHD_00208	1.2e-91	-	-	-	-	-	-	-	-
EDGOKLHD_00209	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EDGOKLHD_00211	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EDGOKLHD_00212	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EDGOKLHD_00213	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
EDGOKLHD_00214	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_00215	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
EDGOKLHD_00216	1.21e-111	-	-	-	-	-	-	-	-
EDGOKLHD_00217	1.96e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
EDGOKLHD_00218	7.19e-68	-	-	-	-	-	-	-	-
EDGOKLHD_00219	1.22e-125	-	-	-	-	-	-	-	-
EDGOKLHD_00220	2.92e-261	-	-	-	L	ko:K07487	-	ko00000	Transposase
EDGOKLHD_00221	4.31e-121	-	-	-	L	ko:K07487	-	ko00000	Transposase
EDGOKLHD_00222	2.98e-90	-	-	-	-	-	-	-	-
EDGOKLHD_00223	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
EDGOKLHD_00224	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
EDGOKLHD_00225	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
EDGOKLHD_00226	1.89e-159	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
EDGOKLHD_00227	4.08e-291	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_00228	6.14e-53	-	-	-	-	-	-	-	-
EDGOKLHD_00229	7.59e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
EDGOKLHD_00230	3.63e-271	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
EDGOKLHD_00231	5.06e-259	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
EDGOKLHD_00232	1.22e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
EDGOKLHD_00233	2.02e-245	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
EDGOKLHD_00234	3.68e-125	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
EDGOKLHD_00235	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
EDGOKLHD_00236	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
EDGOKLHD_00237	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
EDGOKLHD_00238	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
EDGOKLHD_00239	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
EDGOKLHD_00240	2.21e-56	-	-	-	-	-	-	-	-
EDGOKLHD_00241	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
EDGOKLHD_00242	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
EDGOKLHD_00243	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EDGOKLHD_00244	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
EDGOKLHD_00245	2.6e-185	-	-	-	-	-	-	-	-
EDGOKLHD_00246	6.2e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EDGOKLHD_00247	7.84e-92	-	-	-	-	-	-	-	-
EDGOKLHD_00248	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_00249	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_00250	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EDGOKLHD_00251	2.6e-149	-	-	-	-	-	-	-	-
EDGOKLHD_00252	2.81e-55	-	-	-	-	-	-	-	-
EDGOKLHD_00253	1.55e-55	-	-	-	-	-	-	-	-
EDGOKLHD_00254	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_00255	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_00256	1.4e-314	hpk2	-	-	T	-	-	-	Histidine kinase
EDGOKLHD_00257	9.39e-166	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
EDGOKLHD_00258	9.86e-65	-	-	-	-	-	-	-	-
EDGOKLHD_00259	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
EDGOKLHD_00260	3.96e-310	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_00261	3.35e-75	-	-	-	-	-	-	-	-
EDGOKLHD_00262	2.87e-56	-	-	-	-	-	-	-	-
EDGOKLHD_00263	1.45e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
EDGOKLHD_00264	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
EDGOKLHD_00265	1.49e-63	-	-	-	-	-	-	-	-
EDGOKLHD_00266	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
EDGOKLHD_00267	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
EDGOKLHD_00268	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
EDGOKLHD_00269	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
EDGOKLHD_00270	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
EDGOKLHD_00271	1.76e-293	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
EDGOKLHD_00272	2.82e-155	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_00273	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00274	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00275	3.42e-76	-	-	-	M	-	-	-	Lysin motif
EDGOKLHD_00276	1.43e-82	-	-	-	M	-	-	-	LysM domain protein
EDGOKLHD_00277	8.48e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
EDGOKLHD_00278	7.42e-228	-	-	-	-	-	-	-	-
EDGOKLHD_00279	6.88e-170	-	-	-	-	-	-	-	-
EDGOKLHD_00280	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
EDGOKLHD_00281	2.03e-75	-	-	-	-	-	-	-	-
EDGOKLHD_00282	5.31e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EDGOKLHD_00283	1.08e-101	-	-	-	S	ko:K02348	-	ko00000	GNAT family
EDGOKLHD_00284	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_00285	4.76e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
EDGOKLHD_00286	9.97e-50	-	-	-	-	-	-	-	-
EDGOKLHD_00288	1.04e-35	-	-	-	-	-	-	-	-
EDGOKLHD_00289	9.25e-32	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
EDGOKLHD_00290	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_00291	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_00292	9e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_00293	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EDGOKLHD_00294	1.5e-124	-	-	-	K	-	-	-	Cupin domain
EDGOKLHD_00295	8.08e-110	-	-	-	S	-	-	-	ASCH
EDGOKLHD_00296	1.88e-111	-	-	-	K	-	-	-	GNAT family
EDGOKLHD_00297	2.05e-115	-	-	-	K	-	-	-	acetyltransferase
EDGOKLHD_00298	2.06e-30	-	-	-	-	-	-	-	-
EDGOKLHD_00299	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
EDGOKLHD_00300	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_00301	3.6e-242	-	-	-	-	-	-	-	-
EDGOKLHD_00302	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
EDGOKLHD_00303	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
EDGOKLHD_00304	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_00306	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
EDGOKLHD_00307	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
EDGOKLHD_00308	2.97e-41	-	-	-	-	-	-	-	-
EDGOKLHD_00309	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EDGOKLHD_00310	6.4e-54	-	-	-	-	-	-	-	-
EDGOKLHD_00311	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
EDGOKLHD_00312	5.83e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EDGOKLHD_00313	6.71e-80	-	-	-	S	-	-	-	CHY zinc finger
EDGOKLHD_00314	2.21e-284	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EDGOKLHD_00315	1.1e-280	-	-	-	-	-	-	-	-
EDGOKLHD_00316	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
EDGOKLHD_00317	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EDGOKLHD_00318	2.76e-59	-	-	-	-	-	-	-	-
EDGOKLHD_00319	2.39e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
EDGOKLHD_00320	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
EDGOKLHD_00321	1.05e-308	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
EDGOKLHD_00322	6.6e-229	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EDGOKLHD_00323	8.95e-60	-	-	-	-	-	-	-	-
EDGOKLHD_00324	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
EDGOKLHD_00325	3.4e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
EDGOKLHD_00326	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
EDGOKLHD_00327	1.08e-71	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
EDGOKLHD_00328	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
EDGOKLHD_00329	3.25e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
EDGOKLHD_00330	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
EDGOKLHD_00331	2.16e-103	-	-	-	-	-	-	-	-
EDGOKLHD_00332	4.9e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EDGOKLHD_00333	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
EDGOKLHD_00334	1.03e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EDGOKLHD_00335	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
EDGOKLHD_00336	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EDGOKLHD_00337	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_00338	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
EDGOKLHD_00339	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EDGOKLHD_00340	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
EDGOKLHD_00341	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EDGOKLHD_00342	0.0	-	-	-	M	-	-	-	domain protein
EDGOKLHD_00343	2.11e-76	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
EDGOKLHD_00344	7.12e-226	-	-	-	-	-	-	-	-
EDGOKLHD_00345	6.97e-45	-	-	-	-	-	-	-	-
EDGOKLHD_00346	2.35e-52	-	-	-	-	-	-	-	-
EDGOKLHD_00347	2.59e-84	-	-	-	-	-	-	-	-
EDGOKLHD_00348	4.92e-90	-	-	-	S	-	-	-	Immunity protein 63
EDGOKLHD_00349	5.32e-51	-	-	-	-	-	-	-	-
EDGOKLHD_00350	9.2e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
EDGOKLHD_00351	1.58e-262	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
EDGOKLHD_00352	1.69e-187	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
EDGOKLHD_00353	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_00354	8.38e-192	-	-	-	S	-	-	-	hydrolase
EDGOKLHD_00355	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EDGOKLHD_00356	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EDGOKLHD_00358	1.15e-43	-	-	-	-	-	-	-	-
EDGOKLHD_00359	6.24e-25	plnR	-	-	-	-	-	-	-
EDGOKLHD_00360	9.76e-153	-	-	-	-	-	-	-	-
EDGOKLHD_00361	3.29e-32	plnK	-	-	-	-	-	-	-
EDGOKLHD_00362	8.53e-34	plnJ	-	-	-	-	-	-	-
EDGOKLHD_00363	4.08e-39	-	-	-	-	-	-	-	-
EDGOKLHD_00365	5.58e-291	-	-	-	M	-	-	-	Glycosyl transferase family 2
EDGOKLHD_00366	2.08e-160	plnP	-	-	S	-	-	-	CAAX protease self-immunity
EDGOKLHD_00367	1.22e-36	-	-	-	-	-	-	-	-
EDGOKLHD_00368	1.9e-25	plnA	-	-	-	-	-	-	-
EDGOKLHD_00369	2.08e-301	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EDGOKLHD_00370	2.04e-171	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EDGOKLHD_00371	1.05e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EDGOKLHD_00372	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00373	1.93e-31	plnF	-	-	-	-	-	-	-
EDGOKLHD_00374	8.82e-32	-	-	-	-	-	-	-	-
EDGOKLHD_00375	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDGOKLHD_00376	1.49e-309	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
EDGOKLHD_00377	3.26e-124	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00378	5.04e-155	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00379	2.75e-145	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00380	3.34e-147	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00381	1.85e-40	-	-	-	-	-	-	-	-
EDGOKLHD_00382	0.0	-	-	-	L	-	-	-	DNA helicase
EDGOKLHD_00383	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
EDGOKLHD_00384	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EDGOKLHD_00385	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
EDGOKLHD_00386	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_00387	9.68e-34	-	-	-	-	-	-	-	-
EDGOKLHD_00388	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
EDGOKLHD_00389	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_00390	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_00391	6.97e-209	-	-	-	GK	-	-	-	ROK family
EDGOKLHD_00392	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
EDGOKLHD_00393	2.94e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EDGOKLHD_00394	1.23e-262	-	-	-	-	-	-	-	-
EDGOKLHD_00395	5.08e-194	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
EDGOKLHD_00396	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EDGOKLHD_00397	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
EDGOKLHD_00398	4.65e-229	-	-	-	-	-	-	-	-
EDGOKLHD_00399	8.73e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
EDGOKLHD_00400	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
EDGOKLHD_00401	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
EDGOKLHD_00402	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EDGOKLHD_00403	4.08e-270	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
EDGOKLHD_00404	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
EDGOKLHD_00405	3.1e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EDGOKLHD_00406	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EDGOKLHD_00407	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
EDGOKLHD_00408	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EDGOKLHD_00409	3.83e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
EDGOKLHD_00410	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EDGOKLHD_00411	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
EDGOKLHD_00412	2.4e-56	-	-	-	S	-	-	-	ankyrin repeats
EDGOKLHD_00413	5.3e-49	-	-	-	-	-	-	-	-
EDGOKLHD_00414	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
EDGOKLHD_00415	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EDGOKLHD_00416	3.69e-192	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
EDGOKLHD_00417	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EDGOKLHD_00418	1.15e-235	-	-	-	S	-	-	-	DUF218 domain
EDGOKLHD_00419	4.31e-179	-	-	-	-	-	-	-	-
EDGOKLHD_00420	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
EDGOKLHD_00421	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
EDGOKLHD_00422	8.97e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
EDGOKLHD_00423	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
EDGOKLHD_00424	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EDGOKLHD_00425	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EDGOKLHD_00426	2.66e-308	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EDGOKLHD_00427	1.32e-289	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
EDGOKLHD_00428	1.52e-158	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
EDGOKLHD_00429	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EDGOKLHD_00430	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
EDGOKLHD_00431	4.01e-36	-	-	-	-	-	-	-	-
EDGOKLHD_00432	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EDGOKLHD_00433	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EDGOKLHD_00434	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
EDGOKLHD_00435	1.05e-273	-	-	-	J	-	-	-	translation release factor activity
EDGOKLHD_00436	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
EDGOKLHD_00437	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
EDGOKLHD_00438	4.58e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
EDGOKLHD_00439	1.84e-189	-	-	-	-	-	-	-	-
EDGOKLHD_00440	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EDGOKLHD_00441	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EDGOKLHD_00442	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EDGOKLHD_00443	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EDGOKLHD_00444	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
EDGOKLHD_00445	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
EDGOKLHD_00446	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
EDGOKLHD_00447	1.06e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EDGOKLHD_00448	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
EDGOKLHD_00449	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
EDGOKLHD_00450	3.7e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
EDGOKLHD_00451	6.25e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EDGOKLHD_00452	5.62e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EDGOKLHD_00453	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
EDGOKLHD_00454	1.9e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
EDGOKLHD_00455	2.16e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EDGOKLHD_00456	5.3e-110	queT	-	-	S	-	-	-	QueT transporter
EDGOKLHD_00457	5.29e-211	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
EDGOKLHD_00458	8.1e-157	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
EDGOKLHD_00459	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
EDGOKLHD_00460	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
EDGOKLHD_00461	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
EDGOKLHD_00462	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EDGOKLHD_00463	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EDGOKLHD_00464	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
EDGOKLHD_00465	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
EDGOKLHD_00467	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
EDGOKLHD_00468	4.85e-100	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
EDGOKLHD_00469	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EDGOKLHD_00470	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
EDGOKLHD_00471	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EDGOKLHD_00472	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EDGOKLHD_00473	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EDGOKLHD_00474	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
EDGOKLHD_00477	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
EDGOKLHD_00480	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
EDGOKLHD_00481	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EDGOKLHD_00485	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
EDGOKLHD_00486	2.78e-71	-	-	-	S	-	-	-	Cupin domain
EDGOKLHD_00487	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
EDGOKLHD_00488	6.2e-245	ysdE	-	-	P	-	-	-	Citrate transporter
EDGOKLHD_00489	5.35e-187	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
EDGOKLHD_00490	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EDGOKLHD_00491	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EDGOKLHD_00492	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
EDGOKLHD_00493	6.62e-176	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EDGOKLHD_00494	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EDGOKLHD_00495	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EDGOKLHD_00496	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
EDGOKLHD_00497	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
EDGOKLHD_00498	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
EDGOKLHD_00499	6.25e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
EDGOKLHD_00500	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
EDGOKLHD_00501	2.93e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EDGOKLHD_00503	4.34e-31	-	-	-	-	-	-	-	-
EDGOKLHD_00504	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
EDGOKLHD_00507	3.4e-206	-	-	-	G	-	-	-	Peptidase_C39 like family
EDGOKLHD_00508	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
EDGOKLHD_00509	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
EDGOKLHD_00510	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
EDGOKLHD_00511	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
EDGOKLHD_00512	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
EDGOKLHD_00513	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
EDGOKLHD_00514	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
EDGOKLHD_00515	2.58e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EDGOKLHD_00516	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
EDGOKLHD_00517	1.98e-314	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
EDGOKLHD_00518	6.33e-185	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EDGOKLHD_00519	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
EDGOKLHD_00520	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
EDGOKLHD_00521	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
EDGOKLHD_00522	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
EDGOKLHD_00523	3.3e-166	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EDGOKLHD_00524	4.57e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
EDGOKLHD_00525	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
EDGOKLHD_00526	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EDGOKLHD_00527	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
EDGOKLHD_00528	3.84e-126	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
EDGOKLHD_00529	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EDGOKLHD_00530	4.91e-265	yacL	-	-	S	-	-	-	domain protein
EDGOKLHD_00531	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EDGOKLHD_00532	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EDGOKLHD_00533	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EDGOKLHD_00534	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EDGOKLHD_00535	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
EDGOKLHD_00536	2.65e-129	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
EDGOKLHD_00537	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EDGOKLHD_00538	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EDGOKLHD_00539	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
EDGOKLHD_00540	6.91e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EDGOKLHD_00541	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EDGOKLHD_00542	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EDGOKLHD_00543	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EDGOKLHD_00544	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EDGOKLHD_00545	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_00546	1.31e-211	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
EDGOKLHD_00547	4.16e-87	-	-	-	L	-	-	-	nuclease
EDGOKLHD_00548	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EDGOKLHD_00549	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
EDGOKLHD_00550	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EDGOKLHD_00551	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EDGOKLHD_00552	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
EDGOKLHD_00553	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
EDGOKLHD_00554	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EDGOKLHD_00555	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EDGOKLHD_00556	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EDGOKLHD_00557	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EDGOKLHD_00558	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
EDGOKLHD_00559	6.36e-153	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EDGOKLHD_00560	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
EDGOKLHD_00561	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
EDGOKLHD_00562	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
EDGOKLHD_00563	1.53e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EDGOKLHD_00564	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
EDGOKLHD_00565	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
EDGOKLHD_00566	8.87e-269	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
EDGOKLHD_00567	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
EDGOKLHD_00568	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_00569	1.53e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
EDGOKLHD_00570	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EDGOKLHD_00571	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
EDGOKLHD_00572	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
EDGOKLHD_00573	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
EDGOKLHD_00574	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EDGOKLHD_00575	7.63e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EDGOKLHD_00576	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
EDGOKLHD_00577	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
EDGOKLHD_00578	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EDGOKLHD_00579	1.68e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00580	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EDGOKLHD_00581	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EDGOKLHD_00582	0.0	ydaO	-	-	E	-	-	-	amino acid
EDGOKLHD_00583	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
EDGOKLHD_00584	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
EDGOKLHD_00585	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
EDGOKLHD_00586	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
EDGOKLHD_00587	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
EDGOKLHD_00588	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EDGOKLHD_00589	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EDGOKLHD_00590	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EDGOKLHD_00591	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
EDGOKLHD_00592	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
EDGOKLHD_00593	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EDGOKLHD_00594	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
EDGOKLHD_00595	2.22e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
EDGOKLHD_00596	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
EDGOKLHD_00597	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EDGOKLHD_00598	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EDGOKLHD_00599	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
EDGOKLHD_00600	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
EDGOKLHD_00601	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
EDGOKLHD_00602	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EDGOKLHD_00603	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EDGOKLHD_00604	6.63e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
EDGOKLHD_00605	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
EDGOKLHD_00606	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
EDGOKLHD_00607	0.0	nox	-	-	C	-	-	-	NADH oxidase
EDGOKLHD_00608	3.69e-206	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EDGOKLHD_00609	2.45e-310	-	-	-	-	-	-	-	-
EDGOKLHD_00610	8.36e-257	-	-	-	S	-	-	-	Protein conserved in bacteria
EDGOKLHD_00611	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
EDGOKLHD_00612	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
EDGOKLHD_00613	4.57e-171	-	-	-	T	-	-	-	diguanylate cyclase activity
EDGOKLHD_00614	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EDGOKLHD_00615	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
EDGOKLHD_00616	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
EDGOKLHD_00617	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EDGOKLHD_00618	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
EDGOKLHD_00619	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
EDGOKLHD_00620	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EDGOKLHD_00621	8.83e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
EDGOKLHD_00622	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
EDGOKLHD_00623	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EDGOKLHD_00624	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EDGOKLHD_00625	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EDGOKLHD_00626	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
EDGOKLHD_00627	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
EDGOKLHD_00628	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
EDGOKLHD_00629	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
EDGOKLHD_00630	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
EDGOKLHD_00631	7e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
EDGOKLHD_00632	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
EDGOKLHD_00633	6.3e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EDGOKLHD_00634	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EDGOKLHD_00636	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
EDGOKLHD_00637	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
EDGOKLHD_00638	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EDGOKLHD_00639	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
EDGOKLHD_00640	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EDGOKLHD_00641	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EDGOKLHD_00642	5.11e-171	-	-	-	-	-	-	-	-
EDGOKLHD_00643	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EDGOKLHD_00644	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
EDGOKLHD_00645	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
EDGOKLHD_00646	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EDGOKLHD_00647	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EDGOKLHD_00648	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
EDGOKLHD_00649	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_00650	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_00651	6.57e-136	-	-	-	-	-	-	-	-
EDGOKLHD_00652	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EDGOKLHD_00653	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EDGOKLHD_00654	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
EDGOKLHD_00655	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
EDGOKLHD_00656	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
EDGOKLHD_00657	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
EDGOKLHD_00658	1.03e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
EDGOKLHD_00659	1.71e-210	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
EDGOKLHD_00660	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
EDGOKLHD_00661	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
EDGOKLHD_00662	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_00663	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
EDGOKLHD_00664	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EDGOKLHD_00665	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
EDGOKLHD_00666	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EDGOKLHD_00667	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EDGOKLHD_00668	3.15e-158	-	-	-	T	-	-	-	EAL domain
EDGOKLHD_00669	9.79e-191	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
EDGOKLHD_00670	4.22e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_00671	1.7e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
EDGOKLHD_00672	3.38e-70	-	-	-	-	-	-	-	-
EDGOKLHD_00673	2.49e-95	-	-	-	-	-	-	-	-
EDGOKLHD_00674	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
EDGOKLHD_00675	7.34e-180	-	-	-	EGP	-	-	-	Transmembrane secretion effector
EDGOKLHD_00676	1.15e-41	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
EDGOKLHD_00677	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EDGOKLHD_00678	4.13e-182	-	-	-	-	-	-	-	-
EDGOKLHD_00680	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
EDGOKLHD_00681	3.88e-46	-	-	-	-	-	-	-	-
EDGOKLHD_00682	2.08e-117	-	-	-	V	-	-	-	VanZ like family
EDGOKLHD_00683	2.48e-199	-	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_00684	4.18e-99	-	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_00685	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EDGOKLHD_00686	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EDGOKLHD_00687	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EDGOKLHD_00688	1.92e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
EDGOKLHD_00689	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_00690	1.36e-27	-	-	-	-	-	-	-	-
EDGOKLHD_00691	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
EDGOKLHD_00692	4.76e-87	-	-	-	L	-	-	-	Transposase
EDGOKLHD_00693	5.8e-46	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
EDGOKLHD_00694	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
EDGOKLHD_00695	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
EDGOKLHD_00696	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
EDGOKLHD_00697	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
EDGOKLHD_00698	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EDGOKLHD_00699	0.0	oatA	-	-	I	-	-	-	Acyltransferase
EDGOKLHD_00700	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EDGOKLHD_00701	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
EDGOKLHD_00702	1.09e-60	-	-	-	-	-	-	-	-
EDGOKLHD_00703	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
EDGOKLHD_00704	6.12e-115	-	-	-	-	-	-	-	-
EDGOKLHD_00705	7.76e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
EDGOKLHD_00706	3.05e-95	-	-	-	F	-	-	-	Nudix hydrolase
EDGOKLHD_00707	1.48e-27	-	-	-	-	-	-	-	-
EDGOKLHD_00708	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
EDGOKLHD_00709	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
EDGOKLHD_00710	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
EDGOKLHD_00711	1.01e-188	-	-	-	-	-	-	-	-
EDGOKLHD_00712	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
EDGOKLHD_00713	1.86e-267	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EDGOKLHD_00714	5.1e-218	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EDGOKLHD_00715	1.28e-54	-	-	-	-	-	-	-	-
EDGOKLHD_00717	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_00718	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
EDGOKLHD_00719	1.81e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_00720	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_00721	1e-107	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EDGOKLHD_00722	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
EDGOKLHD_00723	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
EDGOKLHD_00724	1.24e-179	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
EDGOKLHD_00725	8.73e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
EDGOKLHD_00726	2.55e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_00727	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
EDGOKLHD_00728	3.08e-93	-	-	-	K	-	-	-	MarR family
EDGOKLHD_00729	8.85e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EDGOKLHD_00730	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EDGOKLHD_00731	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_00732	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EDGOKLHD_00733	1.88e-101	rppH3	-	-	F	-	-	-	NUDIX domain
EDGOKLHD_00734	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
EDGOKLHD_00735	1.61e-36	-	-	-	-	-	-	-	-
EDGOKLHD_00736	2.23e-164	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
EDGOKLHD_00737	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
EDGOKLHD_00738	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
EDGOKLHD_00739	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
EDGOKLHD_00740	2.84e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
EDGOKLHD_00741	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
EDGOKLHD_00742	3.59e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
EDGOKLHD_00743	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
EDGOKLHD_00744	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
EDGOKLHD_00746	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
EDGOKLHD_00748	4.77e-48	-	-	-	L	-	-	-	Helix-turn-helix domain
EDGOKLHD_00749	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EDGOKLHD_00750	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EDGOKLHD_00751	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EDGOKLHD_00752	1.38e-75	-	-	-	-	-	-	-	-
EDGOKLHD_00753	1.08e-71	-	-	-	-	-	-	-	-
EDGOKLHD_00754	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
EDGOKLHD_00755	1.16e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_00756	3.08e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
EDGOKLHD_00757	1.92e-301	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
EDGOKLHD_00758	3.5e-299	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
EDGOKLHD_00759	3.61e-61	-	-	-	S	-	-	-	MORN repeat
EDGOKLHD_00760	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
EDGOKLHD_00761	7.38e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
EDGOKLHD_00762	1.95e-116	-	-	-	-	-	-	-	-
EDGOKLHD_00763	5.74e-32	-	-	-	-	-	-	-	-
EDGOKLHD_00764	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
EDGOKLHD_00765	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
EDGOKLHD_00766	1.59e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
EDGOKLHD_00767	4.25e-211	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
EDGOKLHD_00768	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
EDGOKLHD_00769	2.19e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
EDGOKLHD_00770	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
EDGOKLHD_00771	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
EDGOKLHD_00772	3.37e-60	-	-	-	S	-	-	-	MazG-like family
EDGOKLHD_00773	2.31e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
EDGOKLHD_00774	0.0	-	-	-	M	-	-	-	MucBP domain
EDGOKLHD_00775	1.42e-08	-	-	-	-	-	-	-	-
EDGOKLHD_00776	1.27e-115	-	-	-	S	-	-	-	AAA domain
EDGOKLHD_00777	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
EDGOKLHD_00778	1.09e-123	-	-	-	K	-	-	-	Helix-turn-helix domain
EDGOKLHD_00779	1.6e-219	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_00780	0.0	-	-	-	C	-	-	-	FMN_bind
EDGOKLHD_00782	3.54e-105	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_00783	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EDGOKLHD_00784	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
EDGOKLHD_00785	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
EDGOKLHD_00786	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EDGOKLHD_00787	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EDGOKLHD_00788	5.44e-56	-	-	-	-	-	-	-	-
EDGOKLHD_00789	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
EDGOKLHD_00790	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
EDGOKLHD_00791	1.36e-208	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EDGOKLHD_00792	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EDGOKLHD_00793	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EDGOKLHD_00794	1.12e-243	-	-	-	-	-	-	-	-
EDGOKLHD_00795	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
EDGOKLHD_00796	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
EDGOKLHD_00797	4.77e-130	-	-	-	K	-	-	-	FR47-like protein
EDGOKLHD_00798	1.76e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
EDGOKLHD_00799	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EDGOKLHD_00800	1.51e-82	xylP2	-	-	G	-	-	-	symporter
EDGOKLHD_00801	7.98e-198	xylP2	-	-	G	-	-	-	symporter
EDGOKLHD_00802	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EDGOKLHD_00803	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
EDGOKLHD_00804	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
EDGOKLHD_00805	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
EDGOKLHD_00806	4.09e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
EDGOKLHD_00807	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
EDGOKLHD_00808	8.41e-170	-	-	-	-	-	-	-	-
EDGOKLHD_00809	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
EDGOKLHD_00810	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
EDGOKLHD_00811	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
EDGOKLHD_00812	1.36e-77	-	-	-	-	-	-	-	-
EDGOKLHD_00813	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
EDGOKLHD_00814	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
EDGOKLHD_00815	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
EDGOKLHD_00816	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
EDGOKLHD_00817	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
EDGOKLHD_00818	2.05e-153	-	-	-	I	-	-	-	phosphatase
EDGOKLHD_00819	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EDGOKLHD_00820	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
EDGOKLHD_00821	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_00822	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
EDGOKLHD_00823	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
EDGOKLHD_00824	1.06e-152	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
EDGOKLHD_00825	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
EDGOKLHD_00826	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EDGOKLHD_00834	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
EDGOKLHD_00835	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EDGOKLHD_00836	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_00837	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDGOKLHD_00838	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDGOKLHD_00839	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_00840	1.73e-148	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
EDGOKLHD_00841	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EDGOKLHD_00842	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EDGOKLHD_00843	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EDGOKLHD_00844	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
EDGOKLHD_00845	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EDGOKLHD_00846	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
EDGOKLHD_00847	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EDGOKLHD_00848	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EDGOKLHD_00849	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EDGOKLHD_00850	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EDGOKLHD_00851	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EDGOKLHD_00852	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EDGOKLHD_00853	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
EDGOKLHD_00854	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EDGOKLHD_00855	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EDGOKLHD_00856	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EDGOKLHD_00857	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EDGOKLHD_00858	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EDGOKLHD_00859	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EDGOKLHD_00860	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EDGOKLHD_00861	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EDGOKLHD_00862	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
EDGOKLHD_00863	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
EDGOKLHD_00864	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EDGOKLHD_00865	5.28e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EDGOKLHD_00866	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EDGOKLHD_00867	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EDGOKLHD_00868	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EDGOKLHD_00869	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDGOKLHD_00870	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
EDGOKLHD_00871	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EDGOKLHD_00872	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
EDGOKLHD_00873	5.37e-112	-	-	-	S	-	-	-	NusG domain II
EDGOKLHD_00874	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
EDGOKLHD_00875	3.19e-194	-	-	-	S	-	-	-	FMN_bind
EDGOKLHD_00876	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EDGOKLHD_00877	3.42e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDGOKLHD_00878	3.47e-212	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDGOKLHD_00879	2.49e-186	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDGOKLHD_00880	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EDGOKLHD_00881	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EDGOKLHD_00882	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
EDGOKLHD_00883	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
EDGOKLHD_00884	1.17e-233	-	-	-	S	-	-	-	Membrane
EDGOKLHD_00885	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
EDGOKLHD_00886	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EDGOKLHD_00887	6.73e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EDGOKLHD_00888	4.68e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
EDGOKLHD_00889	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EDGOKLHD_00890	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
EDGOKLHD_00891	6.15e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
EDGOKLHD_00892	2.01e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
EDGOKLHD_00893	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
EDGOKLHD_00894	1.55e-254	-	-	-	K	-	-	-	Helix-turn-helix domain
EDGOKLHD_00895	5.24e-195	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EDGOKLHD_00896	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EDGOKLHD_00897	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
EDGOKLHD_00898	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EDGOKLHD_00899	1.18e-66	-	-	-	-	-	-	-	-
EDGOKLHD_00900	1.07e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
EDGOKLHD_00901	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
EDGOKLHD_00902	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
EDGOKLHD_00903	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
EDGOKLHD_00904	1.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EDGOKLHD_00905	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
EDGOKLHD_00906	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
EDGOKLHD_00907	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
EDGOKLHD_00908	5.69e-185	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
EDGOKLHD_00909	6.87e-33	-	-	-	K	-	-	-	sequence-specific DNA binding
EDGOKLHD_00911	3.88e-20	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EDGOKLHD_00912	3.38e-230	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EDGOKLHD_00913	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EDGOKLHD_00914	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
EDGOKLHD_00915	8.08e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
EDGOKLHD_00916	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
EDGOKLHD_00917	6.5e-215	mleR	-	-	K	-	-	-	LysR family
EDGOKLHD_00918	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
EDGOKLHD_00919	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
EDGOKLHD_00920	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
EDGOKLHD_00921	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
EDGOKLHD_00922	6.07e-33	-	-	-	-	-	-	-	-
EDGOKLHD_00923	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
EDGOKLHD_00924	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
EDGOKLHD_00925	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
EDGOKLHD_00926	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EDGOKLHD_00927	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EDGOKLHD_00928	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
EDGOKLHD_00929	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EDGOKLHD_00930	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
EDGOKLHD_00931	9.47e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
EDGOKLHD_00932	2.92e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
EDGOKLHD_00933	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EDGOKLHD_00934	2.67e-119	yebE	-	-	S	-	-	-	UPF0316 protein
EDGOKLHD_00935	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EDGOKLHD_00936	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
EDGOKLHD_00937	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EDGOKLHD_00938	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
EDGOKLHD_00939	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EDGOKLHD_00940	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EDGOKLHD_00941	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EDGOKLHD_00942	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
EDGOKLHD_00943	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EDGOKLHD_00944	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_00945	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
EDGOKLHD_00946	2.88e-306	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_00947	4.76e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EDGOKLHD_00948	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
EDGOKLHD_00949	4.68e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
EDGOKLHD_00950	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
EDGOKLHD_00951	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
EDGOKLHD_00952	1.94e-245	mocA	-	-	S	-	-	-	Oxidoreductase
EDGOKLHD_00953	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
EDGOKLHD_00955	7.42e-99	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EDGOKLHD_00956	3.88e-66	-	-	-	S	-	-	-	Domain of unknown function DUF1829
EDGOKLHD_00959	6.49e-116	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
EDGOKLHD_00960	6.67e-121	-	-	-	S	-	-	-	T5orf172
EDGOKLHD_00963	6.36e-100	-	-	-	K	-	-	-	Peptidase S24-like
EDGOKLHD_00964	1.45e-46	-	-	-	S	-	-	-	sequence-specific DNA binding
EDGOKLHD_00965	9.15e-77	-	-	-	S	-	-	-	ORF6C domain
EDGOKLHD_00969	2.58e-22	-	-	-	-	-	-	-	-
EDGOKLHD_00971	3.89e-184	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
EDGOKLHD_00972	3.98e-151	-	-	-	S	-	-	-	AAA domain
EDGOKLHD_00973	1.19e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
EDGOKLHD_00974	3.56e-168	-	-	-	S	-	-	-	Putative HNHc nuclease
EDGOKLHD_00975	1.16e-47	-	-	-	L	-	-	-	Helix-turn-helix domain
EDGOKLHD_00976	1.19e-186	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
EDGOKLHD_00978	8.34e-62	-	-	-	-	-	-	-	-
EDGOKLHD_00979	4.14e-20	-	-	-	-	-	-	-	-
EDGOKLHD_00980	1.48e-42	-	-	-	S	-	-	-	YopX protein
EDGOKLHD_00981	1.87e-43	-	-	-	-	-	-	-	-
EDGOKLHD_00982	6.85e-47	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
EDGOKLHD_00984	3.3e-31	-	-	-	S	-	-	-	mRNA binding
EDGOKLHD_00985	8.32e-61	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
EDGOKLHD_00987	1.43e-17	-	-	-	V	-	-	-	HNH nucleases
EDGOKLHD_00988	4.9e-116	-	-	-	L	-	-	-	HNH nucleases
EDGOKLHD_00989	5.71e-60	-	-	-	L	-	-	-	Phage terminase, small subunit
EDGOKLHD_00990	1.67e-219	-	-	-	S	-	-	-	Phage Terminase
EDGOKLHD_00991	1.3e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
EDGOKLHD_00992	1.83e-261	-	-	-	S	-	-	-	Phage portal protein
EDGOKLHD_00993	1.96e-163	-	-	-	S	-	-	-	Clp protease
EDGOKLHD_00994	1.3e-281	-	-	-	S	-	-	-	Phage capsid family
EDGOKLHD_00995	2.88e-69	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
EDGOKLHD_00996	1.21e-32	-	-	-	S	-	-	-	Phage head-tail joining protein
EDGOKLHD_00997	2.3e-51	-	-	-	-	-	-	-	-
EDGOKLHD_00999	6.37e-92	-	-	-	S	-	-	-	Phage tail tube protein
EDGOKLHD_01001	5.58e-06	-	-	-	-	-	-	-	-
EDGOKLHD_01002	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
EDGOKLHD_01003	2.68e-296	-	-	-	S	-	-	-	Phage tail protein
EDGOKLHD_01004	0.0	-	-	-	S	-	-	-	Phage minor structural protein
EDGOKLHD_01005	2.02e-159	-	-	-	-	-	-	-	-
EDGOKLHD_01008	5.59e-67	-	-	-	-	-	-	-	-
EDGOKLHD_01010	1.47e-237	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
EDGOKLHD_01011	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
EDGOKLHD_01013	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
EDGOKLHD_01014	7.64e-316	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_01015	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EDGOKLHD_01017	7.62e-97	-	-	-	-	-	-	-	-
EDGOKLHD_01018	2.9e-139	-	-	-	-	-	-	-	-
EDGOKLHD_01019	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
EDGOKLHD_01020	4.68e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
EDGOKLHD_01021	1.12e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EDGOKLHD_01022	1.01e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
EDGOKLHD_01023	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EDGOKLHD_01024	2.4e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
EDGOKLHD_01025	1.81e-104	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
EDGOKLHD_01026	4.25e-46	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EDGOKLHD_01027	2.21e-67	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
EDGOKLHD_01030	3.67e-19	cps3F	-	-	-	-	-	-	-
EDGOKLHD_01031	3.55e-84	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
EDGOKLHD_01032	3.33e-30	-	-	-	S	-	-	-	Acyltransferase family
EDGOKLHD_01034	7.34e-220	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
EDGOKLHD_01035	3.09e-98	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EDGOKLHD_01036	1.56e-09	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
EDGOKLHD_01037	1.82e-80	tnp2	-	-	L	ko:K07485	-	ko00000	Transposase
EDGOKLHD_01038	3.78e-200	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EDGOKLHD_01039	6.5e-130	-	-	-	L	-	-	-	Integrase
EDGOKLHD_01040	6.03e-174	-	-	-	M	-	-	-	domain protein
EDGOKLHD_01041	2.75e-216	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives, IS30 family
EDGOKLHD_01042	1.09e-165	-	-	-	M	-	-	-	domain protein
EDGOKLHD_01043	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_01044	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
EDGOKLHD_01045	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
EDGOKLHD_01046	9.02e-70	-	-	-	-	-	-	-	-
EDGOKLHD_01047	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
EDGOKLHD_01048	1.95e-41	-	-	-	-	-	-	-	-
EDGOKLHD_01049	1.35e-34	-	-	-	-	-	-	-	-
EDGOKLHD_01050	6.87e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
EDGOKLHD_01051	7.74e-168	-	-	-	-	-	-	-	-
EDGOKLHD_01052	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
EDGOKLHD_01053	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
EDGOKLHD_01054	9.64e-171	lytE	-	-	M	-	-	-	NlpC/P60 family
EDGOKLHD_01055	5.64e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
EDGOKLHD_01056	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
EDGOKLHD_01057	4.02e-166	pbpX	-	-	V	-	-	-	Beta-lactamase
EDGOKLHD_01058	4.22e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EDGOKLHD_01059	6.55e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
EDGOKLHD_01060	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
EDGOKLHD_01061	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
EDGOKLHD_01062	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
EDGOKLHD_01063	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
EDGOKLHD_01064	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
EDGOKLHD_01065	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EDGOKLHD_01066	0.0	-	-	-	-	-	-	-	-
EDGOKLHD_01067	1.49e-252	-	-	-	M	-	-	-	MucBP domain
EDGOKLHD_01068	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
EDGOKLHD_01069	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EDGOKLHD_01070	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
EDGOKLHD_01071	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
EDGOKLHD_01072	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDGOKLHD_01073	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDGOKLHD_01074	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EDGOKLHD_01075	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EDGOKLHD_01076	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
EDGOKLHD_01077	2.5e-132	-	-	-	L	-	-	-	Integrase
EDGOKLHD_01078	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
EDGOKLHD_01079	5.6e-41	-	-	-	-	-	-	-	-
EDGOKLHD_01080	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
EDGOKLHD_01081	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EDGOKLHD_01082	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
EDGOKLHD_01083	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
EDGOKLHD_01084	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EDGOKLHD_01085	5.25e-83	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EDGOKLHD_01086	9.54e-185	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EDGOKLHD_01087	4.97e-292	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EDGOKLHD_01088	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
EDGOKLHD_01089	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EDGOKLHD_01092	2.22e-54	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
EDGOKLHD_01104	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
EDGOKLHD_01105	1.28e-236	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
EDGOKLHD_01106	1.25e-124	-	-	-	-	-	-	-	-
EDGOKLHD_01107	9.14e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EDGOKLHD_01108	1.46e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
EDGOKLHD_01110	5.39e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EDGOKLHD_01111	2.95e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
EDGOKLHD_01112	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
EDGOKLHD_01113	6.48e-215	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
EDGOKLHD_01114	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EDGOKLHD_01115	5.79e-158	-	-	-	-	-	-	-	-
EDGOKLHD_01116	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EDGOKLHD_01117	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_01118	8.62e-132	-	-	-	N	-	-	-	Cell shape-determining protein MreB
EDGOKLHD_01119	1.22e-173	-	-	-	N	-	-	-	Cell shape-determining protein MreB
EDGOKLHD_01120	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
EDGOKLHD_01121	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EDGOKLHD_01122	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EDGOKLHD_01123	2.68e-39	-	-	-	-	-	-	-	-
EDGOKLHD_01124	7.15e-121	mraW1	-	-	J	-	-	-	Putative rRNA methylase
EDGOKLHD_01125	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
EDGOKLHD_01126	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
EDGOKLHD_01127	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
EDGOKLHD_01128	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
EDGOKLHD_01129	5.24e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EDGOKLHD_01130	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
EDGOKLHD_01131	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
EDGOKLHD_01132	1.02e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
EDGOKLHD_01133	2.27e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EDGOKLHD_01134	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_01135	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
EDGOKLHD_01136	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
EDGOKLHD_01137	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
EDGOKLHD_01138	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EDGOKLHD_01139	0.0	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
EDGOKLHD_01141	3.63e-164	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
EDGOKLHD_01142	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_01143	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
EDGOKLHD_01144	4.03e-197	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EDGOKLHD_01145	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_01146	9.47e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
EDGOKLHD_01147	4.58e-56	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EDGOKLHD_01148	7.16e-107	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EDGOKLHD_01149	1.97e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EDGOKLHD_01150	1.3e-138	-	-	-	-	-	-	-	-
EDGOKLHD_01151	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EDGOKLHD_01152	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EDGOKLHD_01153	5.37e-74	-	-	-	-	-	-	-	-
EDGOKLHD_01154	4.56e-78	-	-	-	-	-	-	-	-
EDGOKLHD_01155	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_01156	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_01157	2.95e-117	-	-	-	-	-	-	-	-
EDGOKLHD_01158	7.12e-62	-	-	-	-	-	-	-	-
EDGOKLHD_01159	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
EDGOKLHD_01161	6.4e-120	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EDGOKLHD_01166	5.35e-28	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_01167	5.72e-27	-	-	-	-	-	-	-	-
EDGOKLHD_01168	1.25e-10	-	-	-	-	-	-	-	-
EDGOKLHD_01169	1.53e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
EDGOKLHD_01174	4.34e-16	-	-	-	S	-	-	-	Siphovirus Gp157
EDGOKLHD_01175	1.58e-220	-	-	-	S	-	-	-	helicase activity
EDGOKLHD_01176	5.85e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_01177	3.64e-68	-	-	-	L	-	-	-	AAA domain
EDGOKLHD_01178	3.52e-28	-	-	-	-	-	-	-	-
EDGOKLHD_01179	1.74e-97	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
EDGOKLHD_01180	4.51e-166	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
EDGOKLHD_01181	1.34e-52	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
EDGOKLHD_01182	2.13e-25	-	-	-	-	-	-	-	-
EDGOKLHD_01184	5.93e-38	-	-	-	S	-	-	-	YopX protein
EDGOKLHD_01185	7.73e-51	-	-	-	-	-	-	-	-
EDGOKLHD_01186	4.75e-21	-	-	-	-	-	-	-	-
EDGOKLHD_01188	4.99e-44	-	-	-	-	-	-	-	-
EDGOKLHD_01192	8.83e-35	-	-	-	V	-	-	-	HNH nucleases
EDGOKLHD_01195	4.24e-14	-	-	-	-	-	-	-	-
EDGOKLHD_01196	1.1e-212	-	-	-	S	-	-	-	Phage Terminase
EDGOKLHD_01197	2.87e-127	-	-	-	S	-	-	-	Phage portal protein
EDGOKLHD_01198	6.54e-70	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
EDGOKLHD_01199	1.83e-140	-	-	-	S	-	-	-	Phage capsid family
EDGOKLHD_01200	5.81e-24	-	-	-	-	-	-	-	-
EDGOKLHD_01201	6.11e-32	-	-	-	-	-	-	-	-
EDGOKLHD_01202	1.32e-44	-	-	-	-	-	-	-	-
EDGOKLHD_01203	5.64e-30	-	-	-	-	-	-	-	-
EDGOKLHD_01204	1.07e-43	-	-	-	S	-	-	-	Phage tail tube protein
EDGOKLHD_01206	2.14e-214	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
EDGOKLHD_01208	1.83e-120	-	-	-	LM	-	-	-	DNA recombination
EDGOKLHD_01209	1.75e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
EDGOKLHD_01211	4.34e-55	-	-	-	-	-	-	-	-
EDGOKLHD_01213	1.78e-07	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
EDGOKLHD_01214	4.22e-138	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
EDGOKLHD_01215	6.4e-120	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EDGOKLHD_01220	5.35e-28	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_01221	5.72e-27	-	-	-	-	-	-	-	-
EDGOKLHD_01222	1.25e-10	-	-	-	-	-	-	-	-
EDGOKLHD_01223	1.53e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
EDGOKLHD_01228	4.34e-16	-	-	-	S	-	-	-	Siphovirus Gp157
EDGOKLHD_01229	1.58e-220	-	-	-	S	-	-	-	helicase activity
EDGOKLHD_01230	5.85e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_01231	3.64e-68	-	-	-	L	-	-	-	AAA domain
EDGOKLHD_01232	3.52e-28	-	-	-	-	-	-	-	-
EDGOKLHD_01233	1.74e-97	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
EDGOKLHD_01234	4.51e-166	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
EDGOKLHD_01235	1.34e-52	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
EDGOKLHD_01236	2.13e-25	-	-	-	-	-	-	-	-
EDGOKLHD_01238	5.93e-38	-	-	-	S	-	-	-	YopX protein
EDGOKLHD_01239	6.3e-46	-	-	-	-	-	-	-	-
EDGOKLHD_01240	4.75e-21	-	-	-	-	-	-	-	-
EDGOKLHD_01248	3.38e-12	-	-	-	S	-	-	-	Phage Terminase
EDGOKLHD_01249	4.48e-17	-	-	-	S	-	-	-	Phage Terminase
EDGOKLHD_01250	3.11e-65	-	-	-	S	-	-	-	Phage Terminase
EDGOKLHD_01252	1.71e-10	-	-	-	S	-	-	-	Phage portal protein
EDGOKLHD_01253	1.18e-18	-	-	-	S	-	-	-	Phage portal protein
EDGOKLHD_01254	5.19e-18	-	-	-	S	-	-	-	Phage portal protein
EDGOKLHD_01255	1.39e-12	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Serine dehydrogenase proteinase
EDGOKLHD_01256	2.75e-42	-	-	-	S	-	-	-	Clp protease
EDGOKLHD_01258	6.73e-64	-	-	-	S	-	-	-	Phage capsid family
EDGOKLHD_01259	6.31e-20	-	-	-	S	-	-	-	Phage capsid family
EDGOKLHD_01260	9.25e-19	-	-	-	S	-	-	-	Phage capsid family
EDGOKLHD_01261	2.19e-11	-	-	-	-	-	-	-	-
EDGOKLHD_01262	1.32e-44	-	-	-	-	-	-	-	-
EDGOKLHD_01263	1.14e-12	-	-	-	-	-	-	-	-
EDGOKLHD_01264	1.07e-43	-	-	-	S	-	-	-	Phage tail tube protein
EDGOKLHD_01266	2.14e-214	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
EDGOKLHD_01268	1.83e-120	-	-	-	LM	-	-	-	DNA recombination
EDGOKLHD_01269	1.75e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
EDGOKLHD_01271	4.34e-55	-	-	-	-	-	-	-	-
EDGOKLHD_01273	1.78e-07	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
EDGOKLHD_01274	4.22e-138	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
EDGOKLHD_01276	4.29e-87	-	-	-	-	-	-	-	-
EDGOKLHD_01277	9.03e-16	-	-	-	-	-	-	-	-
EDGOKLHD_01278	3.89e-237	-	-	-	-	-	-	-	-
EDGOKLHD_01279	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
EDGOKLHD_01280	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
EDGOKLHD_01281	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EDGOKLHD_01282	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EDGOKLHD_01283	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
EDGOKLHD_01284	5.16e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
EDGOKLHD_01285	9.14e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
EDGOKLHD_01286	1.79e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
EDGOKLHD_01287	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
EDGOKLHD_01288	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
EDGOKLHD_01289	2.69e-316	dinF	-	-	V	-	-	-	MatE
EDGOKLHD_01290	1.79e-42	-	-	-	-	-	-	-	-
EDGOKLHD_01293	3.48e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
EDGOKLHD_01294	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
EDGOKLHD_01295	4.64e-106	-	-	-	-	-	-	-	-
EDGOKLHD_01296	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
EDGOKLHD_01297	6.25e-138	-	-	-	-	-	-	-	-
EDGOKLHD_01298	0.0	celR	-	-	K	-	-	-	PRD domain
EDGOKLHD_01299	2.7e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
EDGOKLHD_01300	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
EDGOKLHD_01301	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EDGOKLHD_01302	4.29e-310	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_01303	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_01304	1.28e-263	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
EDGOKLHD_01305	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
EDGOKLHD_01306	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDGOKLHD_01307	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
EDGOKLHD_01308	1.34e-131	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
EDGOKLHD_01309	2.77e-271	arcT	-	-	E	-	-	-	Aminotransferase
EDGOKLHD_01310	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
EDGOKLHD_01311	2.43e-18	-	-	-	-	-	-	-	-
EDGOKLHD_01312	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
EDGOKLHD_01313	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
EDGOKLHD_01314	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
EDGOKLHD_01315	0.0	yhaN	-	-	L	-	-	-	AAA domain
EDGOKLHD_01316	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
EDGOKLHD_01317	7.82e-278	-	-	-	-	-	-	-	-
EDGOKLHD_01318	1.39e-232	-	-	-	M	-	-	-	Peptidase family S41
EDGOKLHD_01319	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
EDGOKLHD_01320	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EDGOKLHD_01321	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
EDGOKLHD_01322	3e-127	-	-	-	-	-	-	-	-
EDGOKLHD_01323	3.36e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
EDGOKLHD_01324	5.27e-203	-	-	-	T	-	-	-	Histidine kinase
EDGOKLHD_01325	1.73e-134	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
EDGOKLHD_01326	7.93e-79	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
EDGOKLHD_01327	2.26e-167	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
EDGOKLHD_01328	1.18e-100	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
EDGOKLHD_01329	3.3e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
EDGOKLHD_01330	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EDGOKLHD_01331	5.72e-90	-	-	-	S	-	-	-	NUDIX domain
EDGOKLHD_01332	0.0	-	-	-	S	-	-	-	membrane
EDGOKLHD_01333	1.22e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EDGOKLHD_01334	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
EDGOKLHD_01335	5.12e-285	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EDGOKLHD_01336	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EDGOKLHD_01337	4.28e-136	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
EDGOKLHD_01338	3.39e-138	-	-	-	-	-	-	-	-
EDGOKLHD_01339	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
EDGOKLHD_01340	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_01341	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
EDGOKLHD_01342	0.0	-	-	-	-	-	-	-	-
EDGOKLHD_01343	4.75e-80	-	-	-	-	-	-	-	-
EDGOKLHD_01344	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
EDGOKLHD_01345	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_01346	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_01347	6.29e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EDGOKLHD_01348	7.9e-72	-	-	-	-	-	-	-	-
EDGOKLHD_01349	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
EDGOKLHD_01350	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_01351	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_01352	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
EDGOKLHD_01353	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EDGOKLHD_01354	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
EDGOKLHD_01355	1.45e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EDGOKLHD_01356	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
EDGOKLHD_01357	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
EDGOKLHD_01358	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
EDGOKLHD_01359	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
EDGOKLHD_01360	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
EDGOKLHD_01361	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
EDGOKLHD_01362	8.63e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
EDGOKLHD_01363	1.83e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EDGOKLHD_01364	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
EDGOKLHD_01365	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
EDGOKLHD_01366	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
EDGOKLHD_01367	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
EDGOKLHD_01368	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
EDGOKLHD_01369	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EDGOKLHD_01370	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EDGOKLHD_01371	3.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EDGOKLHD_01372	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EDGOKLHD_01373	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
EDGOKLHD_01374	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
EDGOKLHD_01375	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EDGOKLHD_01376	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EDGOKLHD_01377	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
EDGOKLHD_01378	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EDGOKLHD_01379	2.76e-74	-	-	-	-	-	-	-	-
EDGOKLHD_01380	8.2e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
EDGOKLHD_01381	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
EDGOKLHD_01382	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
EDGOKLHD_01383	9.75e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
EDGOKLHD_01384	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
EDGOKLHD_01385	1.81e-113	-	-	-	-	-	-	-	-
EDGOKLHD_01386	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
EDGOKLHD_01387	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
EDGOKLHD_01388	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
EDGOKLHD_01389	2.42e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EDGOKLHD_01390	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
EDGOKLHD_01391	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EDGOKLHD_01392	6.65e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
EDGOKLHD_01393	3.55e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
EDGOKLHD_01394	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
EDGOKLHD_01395	1.3e-125	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
EDGOKLHD_01396	8.93e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EDGOKLHD_01397	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EDGOKLHD_01398	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
EDGOKLHD_01399	1.38e-155	csrR	-	-	K	-	-	-	response regulator
EDGOKLHD_01400	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EDGOKLHD_01401	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
EDGOKLHD_01402	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
EDGOKLHD_01403	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EDGOKLHD_01404	1.21e-129	-	-	-	S	-	-	-	SdpI/YhfL protein family
EDGOKLHD_01405	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDGOKLHD_01406	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
EDGOKLHD_01407	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EDGOKLHD_01408	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
EDGOKLHD_01409	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
EDGOKLHD_01410	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EDGOKLHD_01411	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EDGOKLHD_01412	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EDGOKLHD_01413	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
EDGOKLHD_01414	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EDGOKLHD_01415	9.72e-146	-	-	-	S	-	-	-	membrane
EDGOKLHD_01416	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
EDGOKLHD_01417	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
EDGOKLHD_01418	0.0	-	-	-	S	-	-	-	membrane
EDGOKLHD_01419	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
EDGOKLHD_01420	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EDGOKLHD_01421	3.24e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EDGOKLHD_01422	2.47e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
EDGOKLHD_01423	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
EDGOKLHD_01424	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
EDGOKLHD_01425	6.61e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
EDGOKLHD_01426	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
EDGOKLHD_01427	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
EDGOKLHD_01428	2.23e-178	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
EDGOKLHD_01429	2.29e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EDGOKLHD_01430	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
EDGOKLHD_01431	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
EDGOKLHD_01432	4.11e-206	-	-	-	-	-	-	-	-
EDGOKLHD_01433	1.34e-232	-	-	-	-	-	-	-	-
EDGOKLHD_01434	4.14e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
EDGOKLHD_01435	5.37e-74	-	-	-	-	-	-	-	-
EDGOKLHD_01436	2.97e-41	-	-	-	-	-	-	-	-
EDGOKLHD_01440	9.81e-27	-	-	-	-	-	-	-	-
EDGOKLHD_01441	6.69e-124	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_01442	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
EDGOKLHD_01443	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
EDGOKLHD_01444	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
EDGOKLHD_01445	3.49e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
EDGOKLHD_01446	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EDGOKLHD_01447	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
EDGOKLHD_01448	5.46e-89	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EDGOKLHD_01449	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EDGOKLHD_01450	3.99e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EDGOKLHD_01451	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EDGOKLHD_01452	5.49e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EDGOKLHD_01453	6.38e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
EDGOKLHD_01454	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
EDGOKLHD_01455	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
EDGOKLHD_01456	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_01457	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_01458	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EDGOKLHD_01459	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EDGOKLHD_01460	2.38e-72	-	-	-	-	-	-	-	-
EDGOKLHD_01461	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
EDGOKLHD_01462	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EDGOKLHD_01463	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EDGOKLHD_01464	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EDGOKLHD_01465	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EDGOKLHD_01466	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EDGOKLHD_01467	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
EDGOKLHD_01468	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
EDGOKLHD_01469	9.9e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EDGOKLHD_01470	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
EDGOKLHD_01471	2.61e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
EDGOKLHD_01472	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
EDGOKLHD_01473	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
EDGOKLHD_01474	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
EDGOKLHD_01475	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EDGOKLHD_01476	1.79e-243	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EDGOKLHD_01477	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EDGOKLHD_01478	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EDGOKLHD_01479	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
EDGOKLHD_01480	7.71e-298	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EDGOKLHD_01481	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EDGOKLHD_01482	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EDGOKLHD_01483	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
EDGOKLHD_01484	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
EDGOKLHD_01485	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EDGOKLHD_01486	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
EDGOKLHD_01487	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EDGOKLHD_01488	1.03e-66	-	-	-	-	-	-	-	-
EDGOKLHD_01489	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EDGOKLHD_01490	1.1e-112	-	-	-	-	-	-	-	-
EDGOKLHD_01491	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
EDGOKLHD_01492	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
EDGOKLHD_01494	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
EDGOKLHD_01495	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
EDGOKLHD_01496	1.42e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EDGOKLHD_01497	6.06e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
EDGOKLHD_01498	1.51e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
EDGOKLHD_01499	5.99e-286	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EDGOKLHD_01500	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EDGOKLHD_01501	1.45e-126	entB	-	-	Q	-	-	-	Isochorismatase family
EDGOKLHD_01502	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
EDGOKLHD_01503	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
EDGOKLHD_01504	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
EDGOKLHD_01505	5.61e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
EDGOKLHD_01506	1.56e-251	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
EDGOKLHD_01507	2.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
EDGOKLHD_01508	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EDGOKLHD_01509	8.02e-230	yneE	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_01510	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EDGOKLHD_01511	1.97e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EDGOKLHD_01512	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EDGOKLHD_01513	2.97e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
EDGOKLHD_01514	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
EDGOKLHD_01515	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EDGOKLHD_01516	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EDGOKLHD_01517	2.95e-92	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
EDGOKLHD_01518	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
EDGOKLHD_01519	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EDGOKLHD_01520	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
EDGOKLHD_01521	5.4e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
EDGOKLHD_01522	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
EDGOKLHD_01523	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
EDGOKLHD_01524	3.06e-206	-	-	-	K	-	-	-	LysR substrate binding domain
EDGOKLHD_01525	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
EDGOKLHD_01526	5.36e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EDGOKLHD_01527	2.46e-120	-	-	-	K	-	-	-	transcriptional regulator
EDGOKLHD_01528	0.0	-	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_01529	6.56e-193	-	-	-	O	-	-	-	Band 7 protein
EDGOKLHD_01530	1.75e-45	-	-	-	L	-	-	-	Pfam:Integrase_AP2
EDGOKLHD_01534	1.19e-13	-	-	-	-	-	-	-	-
EDGOKLHD_01536	1.43e-69	-	-	-	-	-	-	-	-
EDGOKLHD_01537	1.42e-39	-	-	-	-	-	-	-	-
EDGOKLHD_01538	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
EDGOKLHD_01539	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
EDGOKLHD_01540	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
EDGOKLHD_01541	2.05e-55	-	-	-	-	-	-	-	-
EDGOKLHD_01542	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
EDGOKLHD_01543	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
EDGOKLHD_01544	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
EDGOKLHD_01545	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
EDGOKLHD_01546	1.51e-48	-	-	-	-	-	-	-	-
EDGOKLHD_01547	5.79e-21	-	-	-	-	-	-	-	-
EDGOKLHD_01548	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
EDGOKLHD_01549	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_01550	4e-40	-	-	-	S	-	-	-	CsbD-like
EDGOKLHD_01551	1.06e-53	-	-	-	-	-	-	-	-
EDGOKLHD_01552	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EDGOKLHD_01553	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
EDGOKLHD_01554	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EDGOKLHD_01555	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
EDGOKLHD_01556	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
EDGOKLHD_01557	3.76e-62	-	-	-	-	-	-	-	-
EDGOKLHD_01558	2.12e-57	-	-	-	-	-	-	-	-
EDGOKLHD_01559	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EDGOKLHD_01560	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
EDGOKLHD_01561	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
EDGOKLHD_01562	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
EDGOKLHD_01563	2.06e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
EDGOKLHD_01564	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
EDGOKLHD_01565	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
EDGOKLHD_01566	9.23e-245	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
EDGOKLHD_01567	1.01e-249	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EDGOKLHD_01568	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
EDGOKLHD_01569	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
EDGOKLHD_01570	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
EDGOKLHD_01571	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
EDGOKLHD_01572	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
EDGOKLHD_01573	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
EDGOKLHD_01574	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
EDGOKLHD_01575	3.25e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
EDGOKLHD_01577	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EDGOKLHD_01578	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_01579	1.3e-202	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EDGOKLHD_01580	2.39e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EDGOKLHD_01581	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
EDGOKLHD_01582	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EDGOKLHD_01583	3.28e-233	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
EDGOKLHD_01584	2.8e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
EDGOKLHD_01585	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
EDGOKLHD_01586	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EDGOKLHD_01587	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
EDGOKLHD_01588	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EDGOKLHD_01590	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
EDGOKLHD_01592	1.7e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
EDGOKLHD_01593	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
EDGOKLHD_01594	3.2e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
EDGOKLHD_01595	2.85e-266	mccF	-	-	V	-	-	-	LD-carboxypeptidase
EDGOKLHD_01596	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EDGOKLHD_01597	2.13e-312	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
EDGOKLHD_01598	1.55e-81	-	-	-	V	-	-	-	LD-carboxypeptidase
EDGOKLHD_01599	1.64e-132	-	-	-	V	-	-	-	LD-carboxypeptidase
EDGOKLHD_01600	1.99e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
EDGOKLHD_01601	3.99e-158	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EDGOKLHD_01602	1.37e-248	-	-	-	-	-	-	-	-
EDGOKLHD_01603	1.5e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
EDGOKLHD_01604	1.47e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
EDGOKLHD_01605	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
EDGOKLHD_01606	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
EDGOKLHD_01607	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
EDGOKLHD_01608	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EDGOKLHD_01609	1.96e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EDGOKLHD_01610	1.1e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EDGOKLHD_01611	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
EDGOKLHD_01612	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
EDGOKLHD_01613	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
EDGOKLHD_01614	4.75e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
EDGOKLHD_01615	6.38e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
EDGOKLHD_01617	6.17e-165	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
EDGOKLHD_01618	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
EDGOKLHD_01619	2.31e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
EDGOKLHD_01620	5.37e-117	-	-	-	F	-	-	-	NUDIX domain
EDGOKLHD_01621	2.42e-71	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_01622	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
EDGOKLHD_01623	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_01624	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
EDGOKLHD_01625	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
EDGOKLHD_01626	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
EDGOKLHD_01627	1.69e-39	-	-	-	-	-	-	-	-
EDGOKLHD_01628	2.37e-65	-	-	-	-	-	-	-	-
EDGOKLHD_01629	2.82e-190	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
EDGOKLHD_01630	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
EDGOKLHD_01632	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
EDGOKLHD_01633	6.02e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
EDGOKLHD_01634	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
EDGOKLHD_01635	2.14e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
EDGOKLHD_01636	2.79e-181	-	-	-	-	-	-	-	-
EDGOKLHD_01637	7.79e-78	-	-	-	-	-	-	-	-
EDGOKLHD_01638	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
EDGOKLHD_01639	3.2e-288	-	-	-	-	-	-	-	-
EDGOKLHD_01640	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
EDGOKLHD_01641	2.44e-242	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
EDGOKLHD_01642	3.75e-246	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EDGOKLHD_01643	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EDGOKLHD_01644	2.14e-117	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
EDGOKLHD_01645	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_01646	3.22e-304	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
EDGOKLHD_01647	1.98e-66	-	-	-	-	-	-	-	-
EDGOKLHD_01648	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
EDGOKLHD_01649	2.04e-151	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EDGOKLHD_01650	2.64e-172	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EDGOKLHD_01651	5.95e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
EDGOKLHD_01652	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
EDGOKLHD_01653	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EDGOKLHD_01654	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
EDGOKLHD_01655	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
EDGOKLHD_01656	1.56e-227	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_01657	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDGOKLHD_01658	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDGOKLHD_01659	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EDGOKLHD_01660	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
EDGOKLHD_01661	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EDGOKLHD_01662	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EDGOKLHD_01663	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
EDGOKLHD_01664	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EDGOKLHD_01665	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EDGOKLHD_01666	1.1e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
EDGOKLHD_01667	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EDGOKLHD_01668	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EDGOKLHD_01670	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
EDGOKLHD_01671	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
EDGOKLHD_01672	1.23e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
EDGOKLHD_01673	2.48e-252	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
EDGOKLHD_01674	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_01675	4.29e-253	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_01676	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
EDGOKLHD_01677	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
EDGOKLHD_01678	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
EDGOKLHD_01679	2.4e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
EDGOKLHD_01680	2.88e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
EDGOKLHD_01681	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EDGOKLHD_01682	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EDGOKLHD_01683	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_01684	6.46e-109	-	-	-	-	-	-	-	-
EDGOKLHD_01685	8.95e-292	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EDGOKLHD_01686	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EDGOKLHD_01687	3.71e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
EDGOKLHD_01688	5.96e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
EDGOKLHD_01689	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EDGOKLHD_01690	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
EDGOKLHD_01691	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
EDGOKLHD_01692	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
EDGOKLHD_01693	1.25e-39	-	-	-	M	-	-	-	Lysin motif
EDGOKLHD_01694	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
EDGOKLHD_01695	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
EDGOKLHD_01696	7.2e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EDGOKLHD_01697	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
EDGOKLHD_01698	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EDGOKLHD_01699	1.18e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EDGOKLHD_01700	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EDGOKLHD_01701	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
EDGOKLHD_01702	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
EDGOKLHD_01703	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
EDGOKLHD_01704	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
EDGOKLHD_01705	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EDGOKLHD_01706	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
EDGOKLHD_01707	2.02e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
EDGOKLHD_01708	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EDGOKLHD_01709	9.08e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
EDGOKLHD_01710	3.25e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EDGOKLHD_01711	8.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
EDGOKLHD_01712	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
EDGOKLHD_01713	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
EDGOKLHD_01714	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_01715	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_01716	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
EDGOKLHD_01717	2.27e-82	-	-	-	P	-	-	-	Rhodanese Homology Domain
EDGOKLHD_01718	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_01719	1.93e-266	-	-	-	-	-	-	-	-
EDGOKLHD_01720	5.21e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
EDGOKLHD_01721	2.5e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
EDGOKLHD_01722	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
EDGOKLHD_01723	4.44e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EDGOKLHD_01724	2.66e-306	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
EDGOKLHD_01725	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_01726	7.87e-266	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
EDGOKLHD_01727	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
EDGOKLHD_01728	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
EDGOKLHD_01729	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
EDGOKLHD_01730	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
EDGOKLHD_01731	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
EDGOKLHD_01732	4.88e-147	-	-	-	GM	-	-	-	epimerase
EDGOKLHD_01733	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
EDGOKLHD_01734	5.04e-155	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
EDGOKLHD_01735	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
EDGOKLHD_01736	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
EDGOKLHD_01737	6.46e-207	-	-	-	S	-	-	-	Alpha beta hydrolase
EDGOKLHD_01738	5.89e-145	-	-	-	GM	-	-	-	NmrA-like family
EDGOKLHD_01739	9.69e-99	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
EDGOKLHD_01740	3.86e-205	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_01741	1.04e-218	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
EDGOKLHD_01742	1.58e-21	-	-	-	S	-	-	-	Alpha beta hydrolase
EDGOKLHD_01743	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
EDGOKLHD_01744	4.6e-94	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
EDGOKLHD_01745	2.31e-17	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
EDGOKLHD_01746	7.78e-261	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EDGOKLHD_01747	7.05e-172	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
EDGOKLHD_01748	4.87e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_01750	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
EDGOKLHD_01751	9.55e-95	-	-	-	K	-	-	-	MarR family
EDGOKLHD_01752	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
EDGOKLHD_01753	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_01754	2.11e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
EDGOKLHD_01755	5.21e-254	-	-	-	-	-	-	-	-
EDGOKLHD_01756	2.59e-256	-	-	-	-	-	-	-	-
EDGOKLHD_01757	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_01758	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
EDGOKLHD_01759	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EDGOKLHD_01760	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EDGOKLHD_01761	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
EDGOKLHD_01762	1.01e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
EDGOKLHD_01763	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
EDGOKLHD_01764	4.58e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EDGOKLHD_01765	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
EDGOKLHD_01766	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EDGOKLHD_01767	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
EDGOKLHD_01768	2.64e-93	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
EDGOKLHD_01769	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
EDGOKLHD_01770	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EDGOKLHD_01771	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
EDGOKLHD_01772	7.36e-220	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EDGOKLHD_01773	5.49e-286	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EDGOKLHD_01774	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EDGOKLHD_01775	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EDGOKLHD_01776	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EDGOKLHD_01777	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
EDGOKLHD_01778	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
EDGOKLHD_01779	3.23e-214	-	-	-	G	-	-	-	Fructosamine kinase
EDGOKLHD_01780	3.45e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
EDGOKLHD_01781	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EDGOKLHD_01782	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EDGOKLHD_01783	2.56e-76	-	-	-	-	-	-	-	-
EDGOKLHD_01784	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EDGOKLHD_01785	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
EDGOKLHD_01786	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
EDGOKLHD_01787	4.78e-65	-	-	-	-	-	-	-	-
EDGOKLHD_01788	1.73e-67	-	-	-	-	-	-	-	-
EDGOKLHD_01789	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EDGOKLHD_01790	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EDGOKLHD_01791	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDGOKLHD_01792	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
EDGOKLHD_01793	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDGOKLHD_01794	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
EDGOKLHD_01795	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
EDGOKLHD_01796	5.24e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_01797	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EDGOKLHD_01798	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
EDGOKLHD_01799	4.94e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EDGOKLHD_01800	2.55e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EDGOKLHD_01801	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
EDGOKLHD_01802	7.56e-242	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
EDGOKLHD_01803	6.29e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EDGOKLHD_01804	1.45e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EDGOKLHD_01805	8.88e-248	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
EDGOKLHD_01806	8.18e-303	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EDGOKLHD_01807	3.52e-57	-	-	-	-	-	-	-	-
EDGOKLHD_01808	4.47e-42	-	-	-	-	-	-	-	-
EDGOKLHD_01809	9.01e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EDGOKLHD_01810	0.0	-	-	-	G	-	-	-	Major Facilitator
EDGOKLHD_01811	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EDGOKLHD_01812	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EDGOKLHD_01813	5.46e-62	ylxQ	-	-	J	-	-	-	ribosomal protein
EDGOKLHD_01814	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
EDGOKLHD_01815	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
EDGOKLHD_01816	2.79e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
EDGOKLHD_01817	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EDGOKLHD_01818	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EDGOKLHD_01819	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
EDGOKLHD_01820	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
EDGOKLHD_01821	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EDGOKLHD_01822	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EDGOKLHD_01823	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
EDGOKLHD_01824	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EDGOKLHD_01825	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
EDGOKLHD_01826	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
EDGOKLHD_01827	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
EDGOKLHD_01828	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EDGOKLHD_01829	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
EDGOKLHD_01830	1.14e-175	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
EDGOKLHD_01831	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
EDGOKLHD_01832	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
EDGOKLHD_01833	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
EDGOKLHD_01834	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EDGOKLHD_01835	7.8e-123	-	-	-	-	-	-	-	-
EDGOKLHD_01836	1.82e-275	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
EDGOKLHD_01837	5.82e-100	-	-	-	-	-	-	-	-
EDGOKLHD_01838	3.81e-87	-	-	-	-	-	-	-	-
EDGOKLHD_01839	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
EDGOKLHD_01840	8.9e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
EDGOKLHD_01841	1.89e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
EDGOKLHD_01842	2.21e-183	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EDGOKLHD_01843	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EDGOKLHD_01844	2.38e-294	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
EDGOKLHD_01846	3.82e-43	-	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Hydrolase, nudix family
EDGOKLHD_01847	2.41e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
EDGOKLHD_01848	1.75e-43	-	-	-	-	-	-	-	-
EDGOKLHD_01849	1.02e-183	-	-	-	Q	-	-	-	Methyltransferase
EDGOKLHD_01850	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
EDGOKLHD_01851	2.87e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
EDGOKLHD_01852	4.57e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
EDGOKLHD_01853	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EDGOKLHD_01854	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
EDGOKLHD_01855	4.3e-29	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
EDGOKLHD_01856	7.93e-177	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
EDGOKLHD_01857	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EDGOKLHD_01858	6.62e-62	-	-	-	-	-	-	-	-
EDGOKLHD_01859	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EDGOKLHD_01860	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
EDGOKLHD_01861	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EDGOKLHD_01862	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
EDGOKLHD_01863	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
EDGOKLHD_01864	0.0	cps4J	-	-	S	-	-	-	MatE
EDGOKLHD_01865	4.82e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
EDGOKLHD_01866	2.32e-298	-	-	-	-	-	-	-	-
EDGOKLHD_01867	1.94e-244	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
EDGOKLHD_01868	1.4e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
EDGOKLHD_01869	2.33e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
EDGOKLHD_01870	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
EDGOKLHD_01871	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
EDGOKLHD_01872	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
EDGOKLHD_01873	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
EDGOKLHD_01874	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EDGOKLHD_01875	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_01876	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
EDGOKLHD_01877	5.12e-31	-	-	-	-	-	-	-	-
EDGOKLHD_01878	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
EDGOKLHD_01879	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
EDGOKLHD_01880	5.56e-142	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
EDGOKLHD_01881	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EDGOKLHD_01882	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EDGOKLHD_01883	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EDGOKLHD_01884	3.4e-203	-	-	-	S	-	-	-	Tetratricopeptide repeat
EDGOKLHD_01885	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EDGOKLHD_01886	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EDGOKLHD_01887	3.84e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EDGOKLHD_01888	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EDGOKLHD_01889	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
EDGOKLHD_01890	5.09e-241	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
EDGOKLHD_01891	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
EDGOKLHD_01892	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
EDGOKLHD_01893	2.56e-162	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
EDGOKLHD_01894	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
EDGOKLHD_01895	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EDGOKLHD_01896	4.98e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
EDGOKLHD_01897	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
EDGOKLHD_01898	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EDGOKLHD_01899	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
EDGOKLHD_01900	0.0	-	-	-	-	-	-	-	-
EDGOKLHD_01901	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
EDGOKLHD_01902	9.51e-135	-	-	-	-	-	-	-	-
EDGOKLHD_01903	9.43e-259	-	-	-	-	-	-	-	-
EDGOKLHD_01904	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
EDGOKLHD_01905	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
EDGOKLHD_01906	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
EDGOKLHD_01907	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
EDGOKLHD_01908	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
EDGOKLHD_01909	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EDGOKLHD_01910	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
EDGOKLHD_01911	1.42e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
EDGOKLHD_01912	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EDGOKLHD_01913	6.45e-111	-	-	-	-	-	-	-	-
EDGOKLHD_01914	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
EDGOKLHD_01915	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EDGOKLHD_01916	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
EDGOKLHD_01917	2.16e-39	-	-	-	-	-	-	-	-
EDGOKLHD_01918	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
EDGOKLHD_01919	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EDGOKLHD_01920	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EDGOKLHD_01921	5.87e-155	-	-	-	S	-	-	-	repeat protein
EDGOKLHD_01922	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
EDGOKLHD_01923	0.0	-	-	-	N	-	-	-	domain, Protein
EDGOKLHD_01924	1.22e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
EDGOKLHD_01925	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_01926	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
EDGOKLHD_01927	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
EDGOKLHD_01928	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EDGOKLHD_01929	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
EDGOKLHD_01930	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
EDGOKLHD_01931	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EDGOKLHD_01932	7.74e-47	-	-	-	-	-	-	-	-
EDGOKLHD_01933	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
EDGOKLHD_01934	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EDGOKLHD_01935	2.05e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
EDGOKLHD_01936	2.57e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
EDGOKLHD_01937	1.47e-100	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
EDGOKLHD_01938	3.64e-101	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
EDGOKLHD_01939	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EDGOKLHD_01940	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
EDGOKLHD_01941	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
EDGOKLHD_01942	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
EDGOKLHD_01943	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EDGOKLHD_01944	7.71e-294	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EDGOKLHD_01945	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EDGOKLHD_01946	1.92e-207	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EDGOKLHD_01947	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EDGOKLHD_01948	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EDGOKLHD_01949	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EDGOKLHD_01950	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
EDGOKLHD_01951	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
EDGOKLHD_01952	2.12e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EDGOKLHD_01953	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
EDGOKLHD_01954	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
EDGOKLHD_01955	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
EDGOKLHD_01956	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
EDGOKLHD_01957	1.66e-122	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EDGOKLHD_01958	1.44e-146	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
EDGOKLHD_01959	2.17e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EDGOKLHD_01961	4.55e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
EDGOKLHD_01962	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EDGOKLHD_01963	2.24e-262	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
EDGOKLHD_01964	3.7e-26	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
EDGOKLHD_01965	9.68e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
EDGOKLHD_01966	5.57e-247	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
EDGOKLHD_01967	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
EDGOKLHD_01968	1.09e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EDGOKLHD_01969	5.27e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EDGOKLHD_01970	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
EDGOKLHD_01971	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
EDGOKLHD_01972	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
EDGOKLHD_01973	2.34e-266	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
EDGOKLHD_01974	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EDGOKLHD_01975	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EDGOKLHD_01976	3.28e-177	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
EDGOKLHD_01977	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
EDGOKLHD_01978	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_02000	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
EDGOKLHD_02001	1.11e-84	-	-	-	-	-	-	-	-
EDGOKLHD_02002	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
EDGOKLHD_02003	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EDGOKLHD_02004	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
EDGOKLHD_02005	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
EDGOKLHD_02006	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EDGOKLHD_02007	6.53e-115	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
EDGOKLHD_02008	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
EDGOKLHD_02009	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EDGOKLHD_02010	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
EDGOKLHD_02011	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EDGOKLHD_02012	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
EDGOKLHD_02014	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
EDGOKLHD_02015	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
EDGOKLHD_02016	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
EDGOKLHD_02017	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
EDGOKLHD_02018	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
EDGOKLHD_02019	4.44e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
EDGOKLHD_02020	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EDGOKLHD_02021	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
EDGOKLHD_02022	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
EDGOKLHD_02023	6.48e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
EDGOKLHD_02024	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
EDGOKLHD_02025	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
EDGOKLHD_02026	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_02027	1.6e-96	-	-	-	-	-	-	-	-
EDGOKLHD_02028	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EDGOKLHD_02029	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
EDGOKLHD_02030	7.85e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EDGOKLHD_02031	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EDGOKLHD_02032	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
EDGOKLHD_02033	4.53e-122	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
EDGOKLHD_02034	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EDGOKLHD_02035	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
EDGOKLHD_02036	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
EDGOKLHD_02037	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
EDGOKLHD_02038	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EDGOKLHD_02039	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EDGOKLHD_02040	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
EDGOKLHD_02041	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EDGOKLHD_02042	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
EDGOKLHD_02043	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EDGOKLHD_02044	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EDGOKLHD_02045	3.95e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
EDGOKLHD_02046	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDGOKLHD_02047	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
EDGOKLHD_02048	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EDGOKLHD_02049	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EDGOKLHD_02050	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EDGOKLHD_02051	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EDGOKLHD_02052	2.07e-118	-	-	-	-	-	-	-	-
EDGOKLHD_02053	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
EDGOKLHD_02054	1.35e-93	-	-	-	-	-	-	-	-
EDGOKLHD_02055	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EDGOKLHD_02056	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EDGOKLHD_02057	3.85e-130	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
EDGOKLHD_02058	1.39e-32	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
EDGOKLHD_02059	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
EDGOKLHD_02060	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EDGOKLHD_02061	4.47e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
EDGOKLHD_02062	1.11e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EDGOKLHD_02063	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
EDGOKLHD_02064	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
EDGOKLHD_02065	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
EDGOKLHD_02066	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
EDGOKLHD_02067	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
EDGOKLHD_02068	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02069	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
EDGOKLHD_02070	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
EDGOKLHD_02071	5.41e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EDGOKLHD_02072	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
EDGOKLHD_02073	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
EDGOKLHD_02074	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
EDGOKLHD_02075	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
EDGOKLHD_02076	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
EDGOKLHD_02077	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EDGOKLHD_02078	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EDGOKLHD_02079	1.83e-298	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
EDGOKLHD_02080	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_02081	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EDGOKLHD_02082	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
EDGOKLHD_02083	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EDGOKLHD_02084	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
EDGOKLHD_02085	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EDGOKLHD_02086	1.15e-144	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
EDGOKLHD_02087	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EDGOKLHD_02088	1.57e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
EDGOKLHD_02089	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EDGOKLHD_02090	7.24e-291	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
EDGOKLHD_02091	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
EDGOKLHD_02092	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
EDGOKLHD_02093	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
EDGOKLHD_02094	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
EDGOKLHD_02095	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
EDGOKLHD_02096	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
EDGOKLHD_02097	2.96e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
EDGOKLHD_02098	1.34e-52	-	-	-	-	-	-	-	-
EDGOKLHD_02099	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
EDGOKLHD_02100	1.91e-259	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
EDGOKLHD_02101	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_02102	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
EDGOKLHD_02103	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
EDGOKLHD_02104	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
EDGOKLHD_02105	1.88e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
EDGOKLHD_02106	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EDGOKLHD_02107	1.23e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EDGOKLHD_02108	1.73e-150	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EDGOKLHD_02109	9.13e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EDGOKLHD_02110	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
EDGOKLHD_02111	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
EDGOKLHD_02112	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
EDGOKLHD_02113	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
EDGOKLHD_02114	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
EDGOKLHD_02115	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
EDGOKLHD_02116	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EDGOKLHD_02117	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
EDGOKLHD_02118	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EDGOKLHD_02119	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EDGOKLHD_02120	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EDGOKLHD_02121	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EDGOKLHD_02122	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EDGOKLHD_02123	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EDGOKLHD_02124	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
EDGOKLHD_02125	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
EDGOKLHD_02126	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EDGOKLHD_02127	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EDGOKLHD_02128	4.39e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EDGOKLHD_02129	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EDGOKLHD_02130	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EDGOKLHD_02131	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
EDGOKLHD_02132	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
EDGOKLHD_02133	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
EDGOKLHD_02134	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
EDGOKLHD_02135	1.12e-246	ampC	-	-	V	-	-	-	Beta-lactamase
EDGOKLHD_02136	8.57e-41	-	-	-	-	-	-	-	-
EDGOKLHD_02137	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
EDGOKLHD_02138	1.33e-77	-	-	-	-	-	-	-	-
EDGOKLHD_02139	5.37e-182	-	-	-	-	-	-	-	-
EDGOKLHD_02140	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
EDGOKLHD_02141	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02142	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
EDGOKLHD_02143	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
EDGOKLHD_02146	1.07e-54	-	-	-	S	-	-	-	Bacteriophage holin
EDGOKLHD_02147	2.17e-62	-	-	-	-	-	-	-	-
EDGOKLHD_02148	4.64e-257	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
EDGOKLHD_02150	7.53e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
EDGOKLHD_02151	0.0	-	-	-	LM	-	-	-	DNA recombination
EDGOKLHD_02152	2.29e-81	-	-	-	-	-	-	-	-
EDGOKLHD_02153	0.0	-	-	-	D	-	-	-	domain protein
EDGOKLHD_02154	1.42e-83	-	-	-	-	-	-	-	-
EDGOKLHD_02155	7.42e-102	-	-	-	S	-	-	-	Phage tail tube protein, TTP
EDGOKLHD_02156	3.49e-72	-	-	-	-	-	-	-	-
EDGOKLHD_02157	9.24e-116	-	-	-	-	-	-	-	-
EDGOKLHD_02158	9.63e-68	-	-	-	-	-	-	-	-
EDGOKLHD_02159	2.9e-68	-	-	-	-	-	-	-	-
EDGOKLHD_02161	2.43e-221	-	-	-	S	-	-	-	Phage major capsid protein E
EDGOKLHD_02162	2.84e-64	-	-	-	-	-	-	-	-
EDGOKLHD_02165	3.05e-41	-	-	-	-	-	-	-	-
EDGOKLHD_02166	0.0	-	-	-	S	-	-	-	Phage Mu protein F like protein
EDGOKLHD_02167	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
EDGOKLHD_02168	2.99e-272	-	-	-	S	-	-	-	Terminase-like family
EDGOKLHD_02169	1.59e-111	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
EDGOKLHD_02170	7.08e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2829)
EDGOKLHD_02176	3.86e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
EDGOKLHD_02178	6.18e-18	-	-	-	-	-	-	-	-
EDGOKLHD_02180	5.95e-06	-	-	-	-	-	-	-	-
EDGOKLHD_02181	7.79e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EDGOKLHD_02182	2.89e-70	-	-	-	-	-	-	-	-
EDGOKLHD_02183	2.2e-65	-	-	-	-	-	-	-	-
EDGOKLHD_02184	4.41e-218	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
EDGOKLHD_02185	7.88e-78	-	-	-	-	-	-	-	-
EDGOKLHD_02186	1.32e-68	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
EDGOKLHD_02190	4e-106	-	-	-	-	-	-	-	-
EDGOKLHD_02191	7.71e-71	-	-	-	-	-	-	-	-
EDGOKLHD_02194	1.13e-36	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EDGOKLHD_02195	8.29e-51	-	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
EDGOKLHD_02197	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix
EDGOKLHD_02198	1.32e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
EDGOKLHD_02199	6.69e-98	-	-	-	E	-	-	-	IrrE N-terminal-like domain
EDGOKLHD_02200	1.52e-201	-	-	-	J	-	-	-	Domain of unknown function (DUF4041)
EDGOKLHD_02201	4.17e-60	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
EDGOKLHD_02202	8.96e-68	-	-	-	-	-	-	-	-
EDGOKLHD_02203	1.63e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
EDGOKLHD_02206	4.71e-47	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EDGOKLHD_02208	9.51e-48	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
EDGOKLHD_02212	4.23e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF3037)
EDGOKLHD_02213	2.21e-277	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EDGOKLHD_02215	1.98e-40	-	-	-	-	-	-	-	-
EDGOKLHD_02218	7.78e-76	-	-	-	-	-	-	-	-
EDGOKLHD_02219	1.62e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
EDGOKLHD_02222	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
EDGOKLHD_02223	3.56e-259	-	-	-	S	-	-	-	Phage portal protein
EDGOKLHD_02224	2.13e-05	-	-	-	-	-	-	-	-
EDGOKLHD_02225	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
EDGOKLHD_02226	2.22e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
EDGOKLHD_02227	1.82e-89	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
EDGOKLHD_02228	3.76e-70	-	-	-	S	-	-	-	Head-tail joining protein
EDGOKLHD_02230	4.52e-85	-	-	-	-	-	-	-	-
EDGOKLHD_02232	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
EDGOKLHD_02233	1.23e-186	-	-	-	L	-	-	-	DNA replication protein
EDGOKLHD_02234	1.07e-39	-	-	-	-	-	-	-	-
EDGOKLHD_02235	1.14e-12	-	-	-	-	-	-	-	-
EDGOKLHD_02238	2.96e-288	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EDGOKLHD_02239	7.4e-51	-	-	-	-	-	-	-	-
EDGOKLHD_02240	5.38e-57	-	-	-	-	-	-	-	-
EDGOKLHD_02241	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
EDGOKLHD_02242	1.27e-109	-	-	-	K	-	-	-	MarR family
EDGOKLHD_02243	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
EDGOKLHD_02244	0.0	inlJ	-	-	M	-	-	-	MucBP domain
EDGOKLHD_02245	6.58e-24	-	-	-	-	-	-	-	-
EDGOKLHD_02246	3.15e-22	-	-	-	-	-	-	-	-
EDGOKLHD_02247	9.35e-24	-	-	-	-	-	-	-	-
EDGOKLHD_02248	9.35e-24	-	-	-	-	-	-	-	-
EDGOKLHD_02249	2.16e-26	-	-	-	-	-	-	-	-
EDGOKLHD_02250	4.63e-24	-	-	-	-	-	-	-	-
EDGOKLHD_02251	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
EDGOKLHD_02252	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EDGOKLHD_02253	1.75e-33	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02254	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02255	2.1e-33	-	-	-	-	-	-	-	-
EDGOKLHD_02256	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
EDGOKLHD_02257	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
EDGOKLHD_02258	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
EDGOKLHD_02259	0.0	yclK	-	-	T	-	-	-	Histidine kinase
EDGOKLHD_02260	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
EDGOKLHD_02261	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
EDGOKLHD_02262	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
EDGOKLHD_02263	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
EDGOKLHD_02265	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
EDGOKLHD_02266	1.31e-64	-	-	-	-	-	-	-	-
EDGOKLHD_02267	5.61e-273	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
EDGOKLHD_02268	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
EDGOKLHD_02269	2.68e-32	-	-	-	-	-	-	-	-
EDGOKLHD_02271	8.16e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EDGOKLHD_02272	4.27e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
EDGOKLHD_02273	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
EDGOKLHD_02274	2.29e-48	-	-	-	-	-	-	-	-
EDGOKLHD_02275	1.11e-45	-	-	-	-	-	-	-	-
EDGOKLHD_02276	3.06e-100	-	-	-	T	-	-	-	diguanylate cyclase
EDGOKLHD_02277	2.54e-135	-	-	-	T	-	-	-	diguanylate cyclase
EDGOKLHD_02278	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
EDGOKLHD_02279	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
EDGOKLHD_02280	9.95e-108	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EDGOKLHD_02281	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_02282	9.2e-62	-	-	-	-	-	-	-	-
EDGOKLHD_02283	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
EDGOKLHD_02284	5.32e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EDGOKLHD_02285	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
EDGOKLHD_02286	8.69e-295	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
EDGOKLHD_02287	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
EDGOKLHD_02288	1.26e-212	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
EDGOKLHD_02289	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_02290	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EDGOKLHD_02291	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02292	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
EDGOKLHD_02293	2.34e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
EDGOKLHD_02294	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
EDGOKLHD_02295	7.09e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
EDGOKLHD_02296	3.68e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EDGOKLHD_02297	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
EDGOKLHD_02298	2.49e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EDGOKLHD_02299	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EDGOKLHD_02300	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EDGOKLHD_02301	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EDGOKLHD_02302	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
EDGOKLHD_02303	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EDGOKLHD_02304	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EDGOKLHD_02305	1.39e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EDGOKLHD_02306	7.54e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
EDGOKLHD_02307	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
EDGOKLHD_02308	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
EDGOKLHD_02309	1.71e-67	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
EDGOKLHD_02310	2.54e-17	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
EDGOKLHD_02311	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EDGOKLHD_02312	1.35e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EDGOKLHD_02313	4.15e-46	-	-	-	-	-	-	-	-
EDGOKLHD_02314	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
EDGOKLHD_02315	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
EDGOKLHD_02316	0.0	-	-	-	M	-	-	-	domain protein
EDGOKLHD_02317	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
EDGOKLHD_02318	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EDGOKLHD_02319	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
EDGOKLHD_02320	2.39e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EDGOKLHD_02321	2.32e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
EDGOKLHD_02322	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EDGOKLHD_02323	4.32e-247	-	-	-	S	-	-	-	domain, Protein
EDGOKLHD_02324	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
EDGOKLHD_02325	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
EDGOKLHD_02326	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
EDGOKLHD_02327	2.43e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EDGOKLHD_02328	1.91e-198	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
EDGOKLHD_02329	1.79e-92	-	-	-	GK	-	-	-	ROK family
EDGOKLHD_02330	1.13e-112	-	-	-	GK	-	-	-	ROK family
EDGOKLHD_02331	2.08e-199	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDGOKLHD_02332	1.18e-172	rdrA	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
EDGOKLHD_02333	0.0	pflD	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
EDGOKLHD_02334	4.3e-228	-	-	-	K	-	-	-	sugar-binding domain protein
EDGOKLHD_02335	1.81e-160	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
EDGOKLHD_02336	2.13e-182	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EDGOKLHD_02337	2.89e-224	ccpB	-	-	K	-	-	-	lacI family
EDGOKLHD_02338	4.34e-202	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
EDGOKLHD_02339	5e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
EDGOKLHD_02340	1.89e-254	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
EDGOKLHD_02341	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
EDGOKLHD_02342	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EDGOKLHD_02343	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
EDGOKLHD_02344	2.66e-172	-	-	-	-	-	-	-	-
EDGOKLHD_02345	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_02346	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
EDGOKLHD_02347	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
EDGOKLHD_02348	3.25e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
EDGOKLHD_02349	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
EDGOKLHD_02350	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_02351	1.53e-209	-	-	-	-	-	-	-	-
EDGOKLHD_02352	1.23e-75	-	-	-	-	-	-	-	-
EDGOKLHD_02353	1.44e-65	-	-	-	-	-	-	-	-
EDGOKLHD_02354	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
EDGOKLHD_02355	4.09e-89	-	-	-	-	-	-	-	-
EDGOKLHD_02356	2.8e-185	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
EDGOKLHD_02357	2.84e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
EDGOKLHD_02358	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
EDGOKLHD_02359	3.89e-62	-	-	-	-	-	-	-	-
EDGOKLHD_02360	1.57e-71	-	-	-	-	-	-	-	-
EDGOKLHD_02361	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
EDGOKLHD_02362	1.65e-97	-	-	-	-	-	-	-	-
EDGOKLHD_02363	4.15e-78	-	-	-	-	-	-	-	-
EDGOKLHD_02364	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
EDGOKLHD_02365	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
EDGOKLHD_02366	3.84e-94	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
EDGOKLHD_02367	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
EDGOKLHD_02368	5.2e-185	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
EDGOKLHD_02369	1.49e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
EDGOKLHD_02370	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
EDGOKLHD_02371	4.17e-102	uspA3	-	-	T	-	-	-	universal stress protein
EDGOKLHD_02372	1.84e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
EDGOKLHD_02373	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EDGOKLHD_02374	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
EDGOKLHD_02375	3.07e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
EDGOKLHD_02376	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
EDGOKLHD_02377	3.74e-205	-	-	-	S	-	-	-	Putative esterase
EDGOKLHD_02378	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_02379	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EDGOKLHD_02380	1.74e-178	-	-	-	-	-	-	-	-
EDGOKLHD_02381	3.41e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
EDGOKLHD_02382	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
EDGOKLHD_02383	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
EDGOKLHD_02384	5.4e-80	-	-	-	-	-	-	-	-
EDGOKLHD_02385	7.48e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
EDGOKLHD_02386	2.97e-76	-	-	-	-	-	-	-	-
EDGOKLHD_02387	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
EDGOKLHD_02388	6.82e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
EDGOKLHD_02389	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
EDGOKLHD_02390	1.17e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_02391	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_02392	8.91e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
EDGOKLHD_02393	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
EDGOKLHD_02394	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EDGOKLHD_02395	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
EDGOKLHD_02396	5.35e-119	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EDGOKLHD_02397	8.88e-139	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EDGOKLHD_02398	1.46e-131	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EDGOKLHD_02399	3.59e-26	-	-	-	-	-	-	-	-
EDGOKLHD_02400	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EDGOKLHD_02401	5.73e-208	mleR	-	-	K	-	-	-	LysR family
EDGOKLHD_02402	1.06e-147	-	-	-	GM	-	-	-	NAD(P)H-binding
EDGOKLHD_02403	1.57e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
EDGOKLHD_02404	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
EDGOKLHD_02405	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EDGOKLHD_02406	5.46e-218	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
EDGOKLHD_02407	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EDGOKLHD_02408	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EDGOKLHD_02409	3.49e-217	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EDGOKLHD_02410	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
EDGOKLHD_02411	2.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
EDGOKLHD_02412	1.95e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EDGOKLHD_02413	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
EDGOKLHD_02414	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EDGOKLHD_02415	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
EDGOKLHD_02416	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
EDGOKLHD_02417	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
EDGOKLHD_02418	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
EDGOKLHD_02419	1.1e-180	-	-	-	T	-	-	-	EAL domain
EDGOKLHD_02420	2.62e-121	-	-	-	-	-	-	-	-
EDGOKLHD_02421	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
EDGOKLHD_02422	4.17e-163	-	-	-	E	-	-	-	Methionine synthase
EDGOKLHD_02423	2.71e-280	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
EDGOKLHD_02424	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
EDGOKLHD_02425	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EDGOKLHD_02426	5.35e-246	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
EDGOKLHD_02427	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EDGOKLHD_02428	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EDGOKLHD_02429	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EDGOKLHD_02430	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EDGOKLHD_02431	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
EDGOKLHD_02432	1e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EDGOKLHD_02433	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EDGOKLHD_02434	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
EDGOKLHD_02435	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EDGOKLHD_02436	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
EDGOKLHD_02437	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
EDGOKLHD_02438	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
EDGOKLHD_02439	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EDGOKLHD_02440	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
EDGOKLHD_02441	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02442	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EDGOKLHD_02443	4.76e-56	-	-	-	-	-	-	-	-
EDGOKLHD_02444	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
EDGOKLHD_02445	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02446	3.41e-190	-	-	-	-	-	-	-	-
EDGOKLHD_02447	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
EDGOKLHD_02448	7.35e-46	-	-	-	-	-	-	-	-
EDGOKLHD_02449	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
EDGOKLHD_02450	1.76e-114	-	-	-	-	-	-	-	-
EDGOKLHD_02451	4.87e-66	-	-	-	-	-	-	-	-
EDGOKLHD_02452	4.79e-13	-	-	-	-	-	-	-	-
EDGOKLHD_02453	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
EDGOKLHD_02454	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
EDGOKLHD_02455	1.52e-151	-	-	-	-	-	-	-	-
EDGOKLHD_02456	1.21e-69	-	-	-	-	-	-	-	-
EDGOKLHD_02458	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
EDGOKLHD_02459	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
EDGOKLHD_02460	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EDGOKLHD_02461	2.96e-41	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
EDGOKLHD_02462	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
EDGOKLHD_02463	2.28e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
EDGOKLHD_02464	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
EDGOKLHD_02465	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
EDGOKLHD_02466	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
EDGOKLHD_02467	1.65e-267	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
EDGOKLHD_02468	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
EDGOKLHD_02469	1.58e-285	-	-	-	EGP	-	-	-	Transmembrane secretion effector
EDGOKLHD_02470	3.74e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
EDGOKLHD_02471	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EDGOKLHD_02472	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_02473	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_02474	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
EDGOKLHD_02475	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
EDGOKLHD_02476	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_02477	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_02478	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
EDGOKLHD_02479	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EDGOKLHD_02480	7.44e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
EDGOKLHD_02481	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
EDGOKLHD_02482	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
EDGOKLHD_02483	7.63e-107	-	-	-	-	-	-	-	-
EDGOKLHD_02484	5.06e-196	-	-	-	S	-	-	-	hydrolase
EDGOKLHD_02485	6.14e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EDGOKLHD_02486	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
EDGOKLHD_02487	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
EDGOKLHD_02488	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
EDGOKLHD_02489	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
EDGOKLHD_02490	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
EDGOKLHD_02491	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
EDGOKLHD_02492	1.08e-81	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
EDGOKLHD_02493	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
EDGOKLHD_02494	4.3e-44	-	-	-	-	-	-	-	-
EDGOKLHD_02495	5.59e-163	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
EDGOKLHD_02496	0.0	ycaM	-	-	E	-	-	-	amino acid
EDGOKLHD_02497	2e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
EDGOKLHD_02498	8.21e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
EDGOKLHD_02499	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
EDGOKLHD_02500	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_02502	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
EDGOKLHD_02503	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
EDGOKLHD_02504	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EDGOKLHD_02505	1.54e-144	-	-	-	-	-	-	-	-
EDGOKLHD_02506	1.08e-243	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
EDGOKLHD_02507	1.57e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
EDGOKLHD_02508	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EDGOKLHD_02509	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
EDGOKLHD_02510	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_02511	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EDGOKLHD_02512	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
EDGOKLHD_02513	6.64e-238	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
EDGOKLHD_02514	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02515	1.12e-116	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
EDGOKLHD_02516	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
EDGOKLHD_02517	5.04e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
EDGOKLHD_02518	1.14e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EDGOKLHD_02519	9.01e-155	-	-	-	S	-	-	-	Membrane
EDGOKLHD_02520	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
EDGOKLHD_02521	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
EDGOKLHD_02522	7.15e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EDGOKLHD_02523	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
EDGOKLHD_02524	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
EDGOKLHD_02525	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
EDGOKLHD_02526	1.49e-131	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
EDGOKLHD_02527	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
EDGOKLHD_02528	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
EDGOKLHD_02529	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
EDGOKLHD_02530	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EDGOKLHD_02532	2.72e-90	-	-	-	M	-	-	-	LysM domain
EDGOKLHD_02533	3.92e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
EDGOKLHD_02534	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02535	6.76e-270	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
EDGOKLHD_02536	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EDGOKLHD_02537	2e-73	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
EDGOKLHD_02538	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
EDGOKLHD_02539	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
EDGOKLHD_02540	5.3e-302	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
EDGOKLHD_02541	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
EDGOKLHD_02542	2.03e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02544	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EDGOKLHD_02545	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
EDGOKLHD_02546	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EDGOKLHD_02547	2.82e-110	-	-	-	-	-	-	-	-
EDGOKLHD_02548	5.14e-111	yvbK	-	-	K	-	-	-	GNAT family
EDGOKLHD_02549	2.8e-49	-	-	-	-	-	-	-	-
EDGOKLHD_02550	2.81e-64	-	-	-	-	-	-	-	-
EDGOKLHD_02551	5.46e-145	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
EDGOKLHD_02552	2.65e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
EDGOKLHD_02553	1.57e-202	-	-	-	K	-	-	-	LysR substrate binding domain
EDGOKLHD_02554	2.53e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
EDGOKLHD_02555	2.03e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
EDGOKLHD_02556	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
EDGOKLHD_02557	1.15e-179	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
EDGOKLHD_02558	2.92e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
EDGOKLHD_02559	2.47e-97	-	-	-	C	-	-	-	Flavodoxin
EDGOKLHD_02560	1.38e-160	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
EDGOKLHD_02561	1.07e-116	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
EDGOKLHD_02562	1.83e-111	-	-	-	GM	-	-	-	NAD(P)H-binding
EDGOKLHD_02563	7.86e-138	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
EDGOKLHD_02564	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_02566	1.03e-31	-	-	-	C	-	-	-	Flavodoxin
EDGOKLHD_02567	1.69e-08	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_02568	9.99e-147	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EDGOKLHD_02569	2.41e-165	-	-	-	C	-	-	-	Aldo keto reductase
EDGOKLHD_02570	4.02e-181	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
EDGOKLHD_02571	3.08e-178	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
EDGOKLHD_02572	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
EDGOKLHD_02573	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
EDGOKLHD_02574	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
EDGOKLHD_02575	2.4e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
EDGOKLHD_02576	1.12e-105	-	-	-	-	-	-	-	-
EDGOKLHD_02577	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
EDGOKLHD_02578	3.45e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
EDGOKLHD_02579	1.52e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
EDGOKLHD_02580	2.02e-246	-	-	-	C	-	-	-	Aldo/keto reductase family
EDGOKLHD_02582	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_02583	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_02584	5.46e-315	-	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_02587	1.24e-229	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
EDGOKLHD_02588	1.74e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
EDGOKLHD_02589	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EDGOKLHD_02590	3.34e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
EDGOKLHD_02591	1.06e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
EDGOKLHD_02592	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
EDGOKLHD_02593	9.53e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EDGOKLHD_02594	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
EDGOKLHD_02595	4.68e-190	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
EDGOKLHD_02596	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
EDGOKLHD_02597	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
EDGOKLHD_02598	2.33e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
EDGOKLHD_02599	2.67e-220	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_02600	5.06e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
EDGOKLHD_02601	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
EDGOKLHD_02602	1.07e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EDGOKLHD_02603	3.39e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
EDGOKLHD_02604	7.23e-194	-	-	-	-	-	-	-	-
EDGOKLHD_02605	5.82e-134	-	-	-	-	-	-	-	-
EDGOKLHD_02606	2e-52	-	-	-	S	-	-	-	Cytochrome B5
EDGOKLHD_02607	5.02e-117	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EDGOKLHD_02608	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
EDGOKLHD_02609	2.82e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
EDGOKLHD_02610	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDGOKLHD_02611	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
EDGOKLHD_02612	1.56e-108	-	-	-	-	-	-	-	-
EDGOKLHD_02613	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
EDGOKLHD_02614	5.32e-242	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EDGOKLHD_02615	1.72e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EDGOKLHD_02616	3.7e-30	-	-	-	-	-	-	-	-
EDGOKLHD_02617	1.84e-134	-	-	-	-	-	-	-	-
EDGOKLHD_02618	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
EDGOKLHD_02619	1.24e-313	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
EDGOKLHD_02620	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EDGOKLHD_02621	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
EDGOKLHD_02622	3.22e-181	-	-	-	S	-	-	-	zinc-ribbon domain
EDGOKLHD_02624	4.29e-50	-	-	-	-	-	-	-	-
EDGOKLHD_02625	8.58e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
EDGOKLHD_02626	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
EDGOKLHD_02627	0.0	-	-	-	I	-	-	-	acetylesterase activity
EDGOKLHD_02628	1.99e-297	-	-	-	M	-	-	-	Collagen binding domain
EDGOKLHD_02629	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
EDGOKLHD_02630	1.24e-165	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
EDGOKLHD_02631	1.44e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
EDGOKLHD_02632	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
EDGOKLHD_02633	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
EDGOKLHD_02634	8.78e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
EDGOKLHD_02635	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
EDGOKLHD_02636	6.37e-125	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
EDGOKLHD_02637	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
EDGOKLHD_02638	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
EDGOKLHD_02639	7.52e-139	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EDGOKLHD_02640	4.78e-197	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EDGOKLHD_02641	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_02642	0.0	-	-	-	-	-	-	-	-
EDGOKLHD_02643	3.08e-80	-	-	-	-	-	-	-	-
EDGOKLHD_02644	1.52e-239	-	-	-	S	-	-	-	Cell surface protein
EDGOKLHD_02645	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_02646	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
EDGOKLHD_02647	1.61e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_02648	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
EDGOKLHD_02649	8.91e-191	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
EDGOKLHD_02650	2.29e-195	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
EDGOKLHD_02651	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
EDGOKLHD_02653	1.15e-43	-	-	-	-	-	-	-	-
EDGOKLHD_02654	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
EDGOKLHD_02655	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
EDGOKLHD_02656	4.08e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_02657	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EDGOKLHD_02658	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
EDGOKLHD_02659	2.87e-61	-	-	-	-	-	-	-	-
EDGOKLHD_02660	1.48e-149	-	-	-	S	-	-	-	SNARE associated Golgi protein
EDGOKLHD_02661	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
EDGOKLHD_02662	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
EDGOKLHD_02663	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02664	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
EDGOKLHD_02665	2.03e-84	-	-	-	-	-	-	-	-
EDGOKLHD_02666	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
EDGOKLHD_02667	2.86e-72	-	-	-	-	-	-	-	-
EDGOKLHD_02668	1.02e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
EDGOKLHD_02669	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EDGOKLHD_02670	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EDGOKLHD_02671	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_02672	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_02673	7.48e-236	-	-	-	GM	-	-	-	Male sterility protein
EDGOKLHD_02674	4.4e-101	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_02675	4.61e-101	-	-	-	M	-	-	-	LysM domain
EDGOKLHD_02676	3.03e-130	-	-	-	M	-	-	-	Lysin motif
EDGOKLHD_02677	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
EDGOKLHD_02678	1.58e-72	nudA	-	-	S	-	-	-	ASCH
EDGOKLHD_02679	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EDGOKLHD_02680	3.57e-120	-	-	-	-	-	-	-	-
EDGOKLHD_02681	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
EDGOKLHD_02682	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
EDGOKLHD_02683	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
EDGOKLHD_02684	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
EDGOKLHD_02685	1.17e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
EDGOKLHD_02686	5.26e-96	-	-	-	-	-	-	-	-
EDGOKLHD_02687	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EDGOKLHD_02688	5.37e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
EDGOKLHD_02689	2.51e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
EDGOKLHD_02690	1.6e-118	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
EDGOKLHD_02691	5.51e-101	yphH	-	-	S	-	-	-	Cupin domain
EDGOKLHD_02692	2.06e-78	-	-	-	I	-	-	-	sulfurtransferase activity
EDGOKLHD_02693	5.44e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
EDGOKLHD_02694	8.38e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
EDGOKLHD_02695	2.31e-277	-	-	-	-	-	-	-	-
EDGOKLHD_02696	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_02697	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02698	1.3e-226	-	-	-	O	-	-	-	protein import
EDGOKLHD_02699	1.67e-292	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
EDGOKLHD_02700	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
EDGOKLHD_02702	9.38e-91	-	-	-	-	-	-	-	-
EDGOKLHD_02703	3.51e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_02704	0.0	-	-	-	E	-	-	-	Amino Acid
EDGOKLHD_02705	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
EDGOKLHD_02706	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
EDGOKLHD_02707	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
EDGOKLHD_02708	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
EDGOKLHD_02709	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
EDGOKLHD_02710	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
EDGOKLHD_02711	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EDGOKLHD_02712	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
EDGOKLHD_02713	8.53e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
EDGOKLHD_02714	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EDGOKLHD_02715	0.0	-	-	-	-	-	-	-	-
EDGOKLHD_02716	2.69e-99	-	-	-	-	-	-	-	-
EDGOKLHD_02717	4.72e-242	-	-	-	S	-	-	-	Cell surface protein
EDGOKLHD_02718	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_02719	4.62e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
EDGOKLHD_02720	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
EDGOKLHD_02721	1.36e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
EDGOKLHD_02722	1.52e-241	ynjC	-	-	S	-	-	-	Cell surface protein
EDGOKLHD_02724	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_02725	1.47e-83	-	-	-	-	-	-	-	-
EDGOKLHD_02726	1.07e-81	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
EDGOKLHD_02727	1.1e-196	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
EDGOKLHD_02728	7.94e-155	-	-	-	-	-	-	-	-
EDGOKLHD_02729	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
EDGOKLHD_02730	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
EDGOKLHD_02731	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_02732	4.52e-147	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
EDGOKLHD_02733	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
EDGOKLHD_02734	1.38e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EDGOKLHD_02735	7.07e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EDGOKLHD_02736	1.59e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_02737	2.65e-216	-	-	-	GM	-	-	-	NmrA-like family
EDGOKLHD_02738	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
EDGOKLHD_02739	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
EDGOKLHD_02740	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
EDGOKLHD_02741	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
EDGOKLHD_02742	3.27e-170	-	-	-	S	-	-	-	KR domain
EDGOKLHD_02743	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_02744	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
EDGOKLHD_02745	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
EDGOKLHD_02746	1.97e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
EDGOKLHD_02747	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
EDGOKLHD_02748	2.64e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_02749	4.96e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
EDGOKLHD_02750	6.11e-186	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EDGOKLHD_02751	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EDGOKLHD_02752	8.17e-220	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EDGOKLHD_02753	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_02754	4.74e-211	-	-	-	GM	-	-	-	NmrA-like family
EDGOKLHD_02755	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EDGOKLHD_02756	1.4e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
EDGOKLHD_02757	6.38e-195	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
EDGOKLHD_02758	3.86e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_02759	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EDGOKLHD_02760	2.22e-235	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
EDGOKLHD_02761	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_02762	1.23e-268	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
EDGOKLHD_02763	2.4e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_02764	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EDGOKLHD_02765	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
EDGOKLHD_02766	4.54e-202	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
EDGOKLHD_02767	1.16e-209	-	-	-	K	-	-	-	LysR substrate binding domain
EDGOKLHD_02768	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
EDGOKLHD_02769	0.0	-	-	-	S	-	-	-	MucBP domain
EDGOKLHD_02770	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
EDGOKLHD_02771	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
EDGOKLHD_02772	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_02773	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_02774	2.09e-85	-	-	-	-	-	-	-	-
EDGOKLHD_02775	5.15e-16	-	-	-	-	-	-	-	-
EDGOKLHD_02776	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
EDGOKLHD_02777	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EDGOKLHD_02778	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
EDGOKLHD_02779	8.12e-282	-	-	-	S	-	-	-	Membrane
EDGOKLHD_02780	2.97e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
EDGOKLHD_02781	5.35e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
EDGOKLHD_02782	1.35e-55	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
EDGOKLHD_02783	5.36e-76	-	-	-	-	-	-	-	-
EDGOKLHD_02784	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
EDGOKLHD_02785	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
EDGOKLHD_02786	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
EDGOKLHD_02787	3.64e-47	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EDGOKLHD_02788	1.44e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
EDGOKLHD_02789	8.09e-142	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
EDGOKLHD_02790	1.11e-138	-	-	-	GM	-	-	-	NAD(P)H-binding
EDGOKLHD_02791	5.35e-102	-	-	-	GM	-	-	-	SnoaL-like domain
EDGOKLHD_02792	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
EDGOKLHD_02793	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
EDGOKLHD_02794	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_02795	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
EDGOKLHD_02796	9.99e-44	-	-	-	L	ko:K07483	-	ko00000	transposase activity
EDGOKLHD_02798	6.79e-53	-	-	-	-	-	-	-	-
EDGOKLHD_02799	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EDGOKLHD_02800	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
EDGOKLHD_02801	1.92e-94	xylR	-	-	GK	-	-	-	ROK family
EDGOKLHD_02802	4.96e-156	xylR	-	-	GK	-	-	-	ROK family
EDGOKLHD_02803	4.93e-149	-	-	-	-	-	-	-	-
EDGOKLHD_02804	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
EDGOKLHD_02805	1.41e-211	-	-	-	-	-	-	-	-
EDGOKLHD_02806	1.66e-259	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
EDGOKLHD_02807	5.03e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
EDGOKLHD_02808	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
EDGOKLHD_02809	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
EDGOKLHD_02810	2.12e-72	-	-	-	-	-	-	-	-
EDGOKLHD_02811	1.18e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EDGOKLHD_02812	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
EDGOKLHD_02813	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
EDGOKLHD_02814	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
EDGOKLHD_02815	5.36e-305	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EDGOKLHD_02816	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
EDGOKLHD_02817	1.14e-159	vanR	-	-	K	-	-	-	response regulator
EDGOKLHD_02818	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
EDGOKLHD_02819	3.84e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EDGOKLHD_02820	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EDGOKLHD_02821	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
EDGOKLHD_02822	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EDGOKLHD_02823	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
EDGOKLHD_02824	3.98e-200	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
EDGOKLHD_02825	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
EDGOKLHD_02826	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
EDGOKLHD_02827	3.66e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
EDGOKLHD_02828	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
EDGOKLHD_02829	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
EDGOKLHD_02830	5.43e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EDGOKLHD_02831	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
EDGOKLHD_02832	5.69e-300	-	-	-	EK	-	-	-	Aminotransferase, class I
EDGOKLHD_02833	1.11e-169	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
EDGOKLHD_02834	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_02835	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02836	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
EDGOKLHD_02837	8.83e-127	-	-	-	KT	-	-	-	response to antibiotic
EDGOKLHD_02838	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
EDGOKLHD_02839	6.03e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
EDGOKLHD_02840	9.68e-202	-	-	-	S	-	-	-	Putative adhesin
EDGOKLHD_02841	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EDGOKLHD_02842	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
EDGOKLHD_02843	4.31e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
EDGOKLHD_02844	4.35e-262	-	-	-	S	-	-	-	DUF218 domain
EDGOKLHD_02845	9.95e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
EDGOKLHD_02846	1.76e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EDGOKLHD_02847	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EDGOKLHD_02848	6.26e-101	-	-	-	-	-	-	-	-
EDGOKLHD_02849	5.43e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
EDGOKLHD_02850	8.33e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
EDGOKLHD_02851	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
EDGOKLHD_02852	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
EDGOKLHD_02853	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
EDGOKLHD_02854	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EDGOKLHD_02855	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
EDGOKLHD_02856	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EDGOKLHD_02857	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
EDGOKLHD_02858	8.79e-199	-	-	-	GM	-	-	-	NmrA-like family
EDGOKLHD_02859	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EDGOKLHD_02860	5.93e-163	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
EDGOKLHD_02862	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EDGOKLHD_02863	3.43e-303	-	-	-	S	-	-	-	module of peptide synthetase
EDGOKLHD_02864	4.71e-135	-	-	-	-	-	-	-	-
EDGOKLHD_02865	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
EDGOKLHD_02866	7.43e-77	-	-	-	S	-	-	-	Enterocin A Immunity
EDGOKLHD_02867	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
EDGOKLHD_02868	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
EDGOKLHD_02869	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
EDGOKLHD_02870	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
EDGOKLHD_02871	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
EDGOKLHD_02872	1.9e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
EDGOKLHD_02873	1.03e-34	-	-	-	-	-	-	-	-
EDGOKLHD_02874	4.23e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
EDGOKLHD_02876	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
EDGOKLHD_02877	4.24e-226	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
EDGOKLHD_02878	2.58e-73	-	-	-	-	-	-	-	-
EDGOKLHD_02881	8.03e-198	-	-	-	-	-	-	-	-
EDGOKLHD_02882	0.0	-	-	-	S	-	-	-	Phage minor structural protein
EDGOKLHD_02883	3.12e-281	-	-	-	S	-	-	-	Phage tail protein
EDGOKLHD_02884	1.46e-258	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
EDGOKLHD_02886	7.52e-19	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
EDGOKLHD_02887	5.65e-94	-	-	-	S	-	-	-	Phage tail tube protein
EDGOKLHD_02888	1.77e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
EDGOKLHD_02889	1.85e-36	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
EDGOKLHD_02890	1.01e-15	-	-	-	S	-	-	-	Phage head-tail joining protein
EDGOKLHD_02891	1.17e-30	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
EDGOKLHD_02892	1.54e-146	-	-	-	S	-	-	-	Phage capsid family
EDGOKLHD_02893	3.31e-100	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
EDGOKLHD_02894	3.46e-180	-	-	-	S	-	-	-	Phage portal protein
EDGOKLHD_02896	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
EDGOKLHD_02897	1.02e-50	-	-	-	L	-	-	-	Phage terminase, small subunit
EDGOKLHD_02898	3.48e-79	-	-	-	V	-	-	-	HNH nucleases
EDGOKLHD_02902	4.79e-18	-	-	-	-	-	-	-	-
EDGOKLHD_02904	6.85e-47	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
EDGOKLHD_02905	6.13e-25	-	-	-	-	-	-	-	-
EDGOKLHD_02906	5.36e-38	-	-	-	S	-	-	-	YopX protein
EDGOKLHD_02907	4.14e-20	-	-	-	-	-	-	-	-
EDGOKLHD_02908	5.02e-63	-	-	-	-	-	-	-	-
EDGOKLHD_02910	3.82e-183	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
EDGOKLHD_02911	1e-41	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
EDGOKLHD_02922	2.58e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_02923	2.79e-78	-	-	-	S	-	-	-	ORF6C domain
EDGOKLHD_02924	3.56e-47	-	-	-	S	-	-	-	sequence-specific DNA binding
EDGOKLHD_02925	6.36e-100	-	-	-	K	-	-	-	Peptidase S24-like
EDGOKLHD_02928	7.78e-46	-	-	-	-	-	-	-	-
EDGOKLHD_02930	5.86e-31	-	-	-	-	-	-	-	-
EDGOKLHD_02935	6.05e-58	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EDGOKLHD_02936	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
EDGOKLHD_02937	4.22e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
EDGOKLHD_02938	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
EDGOKLHD_02939	5.81e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
EDGOKLHD_02940	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
EDGOKLHD_02941	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
EDGOKLHD_02942	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EDGOKLHD_02943	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EDGOKLHD_02944	7.21e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EDGOKLHD_02945	1.45e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
EDGOKLHD_02946	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EDGOKLHD_02948	1.88e-106	-	-	-	-	-	-	-	-
EDGOKLHD_02949	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
EDGOKLHD_02951	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
EDGOKLHD_02952	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EDGOKLHD_02953	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
EDGOKLHD_02954	1.01e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
EDGOKLHD_02955	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
EDGOKLHD_02956	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
EDGOKLHD_02957	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
EDGOKLHD_02958	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
EDGOKLHD_02959	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
EDGOKLHD_02960	1.56e-131	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EDGOKLHD_02962	2.77e-30	-	-	-	-	-	-	-	-
EDGOKLHD_02964	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
EDGOKLHD_02965	4.79e-272	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
EDGOKLHD_02966	4.4e-138	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
EDGOKLHD_02967	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
EDGOKLHD_02968	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
EDGOKLHD_02969	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EDGOKLHD_02970	7.91e-83	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EDGOKLHD_02971	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
EDGOKLHD_02972	1.32e-214	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EDGOKLHD_02973	1.68e-315	-	-	-	EGP	-	-	-	Major Facilitator
EDGOKLHD_02975	4.54e-54	-	-	-	-	-	-	-	-
EDGOKLHD_02976	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
EDGOKLHD_02977	3.74e-125	-	-	-	V	-	-	-	VanZ like family
EDGOKLHD_02978	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
EDGOKLHD_02979	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
EDGOKLHD_02980	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDGOKLHD_02981	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
EDGOKLHD_02982	1.05e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
EDGOKLHD_02983	1.66e-40	-	-	-	FG	-	-	-	HIT domain
EDGOKLHD_02984	3.23e-73	-	-	-	FG	-	-	-	HIT domain
EDGOKLHD_02985	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
EDGOKLHD_02986	4.29e-101	-	-	-	-	-	-	-	-
EDGOKLHD_02987	3.73e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
EDGOKLHD_02988	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
EDGOKLHD_02989	0.0	cadA	-	-	P	-	-	-	P-type ATPase
EDGOKLHD_02991	4.21e-158	-	-	-	S	-	-	-	YjbR
EDGOKLHD_02992	5.51e-284	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
EDGOKLHD_02993	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EDGOKLHD_02994	2.9e-255	glmS2	-	-	M	-	-	-	SIS domain
EDGOKLHD_02995	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
EDGOKLHD_02996	6.21e-37	-	-	-	S	-	-	-	Belongs to the LOG family
EDGOKLHD_02997	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
EDGOKLHD_02998	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
EDGOKLHD_02999	2.65e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EDGOKLHD_03000	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
EDGOKLHD_03001	3.9e-209	-	-	-	GM	-	-	-	NmrA-like family
EDGOKLHD_03002	2.71e-89	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
EDGOKLHD_03003	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
EDGOKLHD_03004	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
EDGOKLHD_03005	1.7e-70	-	-	-	-	-	-	-	-
EDGOKLHD_03006	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
EDGOKLHD_03007	2.11e-82	-	-	-	-	-	-	-	-
EDGOKLHD_03008	1.36e-112	-	-	-	-	-	-	-	-
EDGOKLHD_03009	3.22e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
EDGOKLHD_03010	2.27e-74	-	-	-	-	-	-	-	-
EDGOKLHD_03011	4.79e-21	-	-	-	-	-	-	-	-
EDGOKLHD_03012	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
EDGOKLHD_03013	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
EDGOKLHD_03014	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
EDGOKLHD_03015	2.66e-155	-	-	-	S	-	-	-	membrane
EDGOKLHD_03016	2.55e-145	-	-	-	S	-	-	-	VIT family
EDGOKLHD_03017	5.12e-242	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
EDGOKLHD_03018	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
EDGOKLHD_03019	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
EDGOKLHD_03020	4.26e-54	-	-	-	-	-	-	-	-
EDGOKLHD_03021	2.07e-97	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
EDGOKLHD_03022	2.52e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
EDGOKLHD_03023	7.21e-35	-	-	-	-	-	-	-	-
EDGOKLHD_03024	2.55e-65	-	-	-	-	-	-	-	-
EDGOKLHD_03025	1.02e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
EDGOKLHD_03026	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
EDGOKLHD_03027	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
EDGOKLHD_03028	4.21e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
EDGOKLHD_03029	1.44e-99	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
EDGOKLHD_03030	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
EDGOKLHD_03031	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
EDGOKLHD_03032	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
EDGOKLHD_03033	8.02e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
EDGOKLHD_03034	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
EDGOKLHD_03035	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
EDGOKLHD_03036	2.07e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
EDGOKLHD_03037	1.05e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
EDGOKLHD_03038	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EDGOKLHD_03039	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
EDGOKLHD_03040	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
EDGOKLHD_03041	1.3e-65	-	-	-	-	-	-	-	-
EDGOKLHD_03042	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
EDGOKLHD_03043	0.0	-	-	-	-	-	-	-	-
EDGOKLHD_03044	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
EDGOKLHD_03045	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_03046	7.73e-175	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
EDGOKLHD_03047	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
EDGOKLHD_03048	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EDGOKLHD_03049	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
EDGOKLHD_03050	4.45e-38	-	-	-	-	-	-	-	-
EDGOKLHD_03051	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
EDGOKLHD_03052	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
EDGOKLHD_03053	6.18e-71	-	-	-	-	-	-	-	-
EDGOKLHD_03054	5.77e-81	-	-	-	-	-	-	-	-
EDGOKLHD_03056	5.13e-138	-	-	-	-	-	-	-	-
EDGOKLHD_03057	1.43e-67	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
EDGOKLHD_03058	5.87e-207	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
EDGOKLHD_03059	1.37e-135	-	-	-	K	-	-	-	transcriptional regulator
EDGOKLHD_03060	1.02e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
EDGOKLHD_03061	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EDGOKLHD_03062	1.02e-163	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
EDGOKLHD_03063	2.93e-234	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
EDGOKLHD_03064	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
EDGOKLHD_03065	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EDGOKLHD_03066	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
EDGOKLHD_03067	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
EDGOKLHD_03068	1.01e-26	-	-	-	-	-	-	-	-
EDGOKLHD_03069	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
EDGOKLHD_03070	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
EDGOKLHD_03071	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
EDGOKLHD_03072	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
EDGOKLHD_03073	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EDGOKLHD_03074	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
EDGOKLHD_03075	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
EDGOKLHD_03076	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
EDGOKLHD_03077	7.12e-159	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_03078	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
EDGOKLHD_03079	7.83e-60	-	-	-	-	-	-	-	-
EDGOKLHD_03080	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
EDGOKLHD_03081	1.03e-65	-	-	-	-	-	-	-	-
EDGOKLHD_03082	2.8e-316	-	-	-	S	-	-	-	Putative metallopeptidase domain
EDGOKLHD_03083	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
EDGOKLHD_03084	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EDGOKLHD_03085	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
EDGOKLHD_03086	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EDGOKLHD_03087	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
EDGOKLHD_03088	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
EDGOKLHD_03089	4.73e-242	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EDGOKLHD_03090	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
EDGOKLHD_03091	5.02e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
EDGOKLHD_03092	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
EDGOKLHD_03093	7.65e-282	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
EDGOKLHD_03094	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
EDGOKLHD_03095	4.56e-142	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
EDGOKLHD_03096	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
EDGOKLHD_03097	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EDGOKLHD_03098	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
EDGOKLHD_03099	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
EDGOKLHD_03100	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EDGOKLHD_03101	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
EDGOKLHD_03102	6.68e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
EDGOKLHD_03103	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
EDGOKLHD_03104	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
EDGOKLHD_03105	1.43e-251	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
EDGOKLHD_03106	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EDGOKLHD_03107	5.16e-248	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
EDGOKLHD_03108	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
EDGOKLHD_03109	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
EDGOKLHD_03110	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EDGOKLHD_03111	3.65e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EDGOKLHD_03112	2.26e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EDGOKLHD_03113	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
EDGOKLHD_03114	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EDGOKLHD_03115	2.83e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EDGOKLHD_03116	3.31e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EDGOKLHD_03117	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
EDGOKLHD_03118	5.56e-212	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
EDGOKLHD_03119	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
EDGOKLHD_03120	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EDGOKLHD_03121	2.09e-83	-	-	-	-	-	-	-	-
EDGOKLHD_03122	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
EDGOKLHD_03123	9.03e-173	-	-	-	K	-	-	-	UTRA domain
EDGOKLHD_03124	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDGOKLHD_03125	3.06e-212	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EDGOKLHD_03126	1.58e-207	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
EDGOKLHD_03127	1.94e-270	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
EDGOKLHD_03128	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_03129	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EDGOKLHD_03130	1.51e-199	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
EDGOKLHD_03131	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_03132	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_03133	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EDGOKLHD_03134	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
EDGOKLHD_03135	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
EDGOKLHD_03136	2.66e-222	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
EDGOKLHD_03137	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
EDGOKLHD_03138	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
EDGOKLHD_03140	1.15e-236	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EDGOKLHD_03141	9e-187	yxeH	-	-	S	-	-	-	hydrolase
EDGOKLHD_03142	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EDGOKLHD_03143	8.34e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EDGOKLHD_03144	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
EDGOKLHD_03145	2.97e-60	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
EDGOKLHD_03146	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EDGOKLHD_03147	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EDGOKLHD_03148	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
EDGOKLHD_03149	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
EDGOKLHD_03150	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
EDGOKLHD_03151	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EDGOKLHD_03152	1.1e-103	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EDGOKLHD_03153	2.5e-160	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
EDGOKLHD_03154	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
EDGOKLHD_03155	1.09e-66	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EDGOKLHD_03156	4.84e-14	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EDGOKLHD_03157	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
EDGOKLHD_03158	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
EDGOKLHD_03159	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
EDGOKLHD_03160	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
EDGOKLHD_03161	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EDGOKLHD_03162	1.2e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
EDGOKLHD_03163	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
EDGOKLHD_03164	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EDGOKLHD_03165	2.54e-210	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EDGOKLHD_03166	8.64e-113	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EDGOKLHD_03167	6.99e-80	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EDGOKLHD_03168	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EDGOKLHD_03169	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EDGOKLHD_03170	3.83e-174	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
EDGOKLHD_03171	2.93e-200	nanK	-	-	GK	-	-	-	ROK family
EDGOKLHD_03172	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
EDGOKLHD_03173	3.53e-158	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EDGOKLHD_03174	2.28e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
EDGOKLHD_03175	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
EDGOKLHD_03176	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
EDGOKLHD_03177	1.06e-253	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_03178	1.06e-16	-	-	-	-	-	-	-	-
EDGOKLHD_03179	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
EDGOKLHD_03180	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
EDGOKLHD_03181	5.38e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
EDGOKLHD_03182	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EDGOKLHD_03183	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EDGOKLHD_03184	9.62e-19	-	-	-	-	-	-	-	-
EDGOKLHD_03185	6.12e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
EDGOKLHD_03186	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
EDGOKLHD_03188	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
EDGOKLHD_03189	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
EDGOKLHD_03190	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_03191	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
EDGOKLHD_03192	4.04e-94	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EDGOKLHD_03193	1.45e-162	-	-	-	S	-	-	-	Membrane
EDGOKLHD_03194	1.31e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
EDGOKLHD_03195	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
EDGOKLHD_03196	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
EDGOKLHD_03197	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
EDGOKLHD_03198	4.67e-314	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
EDGOKLHD_03199	3.4e-229	rhaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
EDGOKLHD_03200	1.05e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
EDGOKLHD_03201	2.79e-180	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EDGOKLHD_03202	2.39e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EDGOKLHD_03203	0.0	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
EDGOKLHD_03204	4.02e-205	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
EDGOKLHD_03205	0.0	-	2.3.1.204, 3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
EDGOKLHD_03206	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
EDGOKLHD_03207	2.66e-248	-	-	-	K	-	-	-	Transcriptional regulator
EDGOKLHD_03208	0.0	ypdD	-	-	G	-	-	-	Glycosyl hydrolase family 92
EDGOKLHD_03209	1.81e-274	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EDGOKLHD_03210	3.76e-212	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
EDGOKLHD_03211	0.0	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
EDGOKLHD_03212	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EDGOKLHD_03213	1.71e-139	ypcB	-	-	S	-	-	-	integral membrane protein
EDGOKLHD_03214	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
EDGOKLHD_03215	0.0	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Domain of unknown function (DUF3502)
EDGOKLHD_03216	6.47e-213	lplC	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EDGOKLHD_03217	1.29e-231	ypdA	-	-	U	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EDGOKLHD_03218	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
EDGOKLHD_03219	9.5e-200	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
EDGOKLHD_03220	0.0	mdlA2	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
EDGOKLHD_03221	0.0	yknV	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EDGOKLHD_03222	1.48e-247	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
EDGOKLHD_03223	1.91e-201	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
EDGOKLHD_03224	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
EDGOKLHD_03225	2.5e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
EDGOKLHD_03226	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
EDGOKLHD_03227	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
EDGOKLHD_03228	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
EDGOKLHD_03229	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
EDGOKLHD_03230	3.71e-132	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
EDGOKLHD_03231	7.42e-62	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
EDGOKLHD_03232	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EDGOKLHD_03233	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EDGOKLHD_03234	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EDGOKLHD_03235	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
EDGOKLHD_03236	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
EDGOKLHD_03237	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
EDGOKLHD_03238	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
EDGOKLHD_03239	1.44e-185	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
EDGOKLHD_03240	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EDGOKLHD_03241	1.08e-13	degV1	-	-	S	-	-	-	DegV family
EDGOKLHD_03242	4.35e-164	degV1	-	-	S	-	-	-	DegV family
EDGOKLHD_03243	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
EDGOKLHD_03244	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
EDGOKLHD_03246	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EDGOKLHD_03247	0.0	-	-	-	-	-	-	-	-
EDGOKLHD_03249	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
EDGOKLHD_03250	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
EDGOKLHD_03251	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EDGOKLHD_03252	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EDGOKLHD_03253	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
EDGOKLHD_03254	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
EDGOKLHD_03255	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
EDGOKLHD_03256	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDGOKLHD_03257	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EDGOKLHD_03259	2.48e-05	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EDGOKLHD_03263	9.14e-64	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
EDGOKLHD_03264	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EDGOKLHD_03265	5.49e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
EDGOKLHD_03267	4.44e-205	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
EDGOKLHD_03270	7.24e-17	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EDGOKLHD_03271	1.9e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EDGOKLHD_03272	2.79e-07	-	-	-	-	-	-	-	-
EDGOKLHD_03273	2.65e-99	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
EDGOKLHD_03274	1.62e-157	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EDGOKLHD_03275	1.21e-131	-	-	-	-	-	-	-	-
EDGOKLHD_03276	6.14e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EDGOKLHD_03277	7.19e-137	-	-	-	L	-	-	-	Resolvase, N terminal domain
EDGOKLHD_03278	3.35e-106	-	-	-	L	-	-	-	Integrase core domain
EDGOKLHD_03279	6.79e-65	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EDGOKLHD_03281	5.68e-45	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
EDGOKLHD_03282	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
EDGOKLHD_03283	1.26e-130	-	-	-	L	-	-	-	Resolvase, N terminal domain
EDGOKLHD_03284	8.8e-82	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_03285	0.0	-	-	-	M	-	-	-	domain protein
EDGOKLHD_03286	7.64e-132	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
EDGOKLHD_03287	1.48e-60	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
EDGOKLHD_03288	1.23e-108	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
EDGOKLHD_03289	4.21e-313	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
EDGOKLHD_03290	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
EDGOKLHD_03291	6.37e-55	-	-	-	S	-	-	-	MORN repeat
EDGOKLHD_03292	1.07e-82	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EDGOKLHD_03293	4.02e-260	-	-	-	M	-	-	-	Glycosyl transferase family 2
EDGOKLHD_03294	1.1e-90	-	-	-	-	-	-	-	-
EDGOKLHD_03295	1.58e-68	-	-	-	-	-	-	-	-
EDGOKLHD_03296	8.88e-40	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EDGOKLHD_03297	1.2e-53	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
EDGOKLHD_03298	5.09e-283	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EDGOKLHD_03299	6.31e-38	-	-	-	-	-	-	-	-
EDGOKLHD_03305	1.56e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
EDGOKLHD_03307	6.87e-28	-	-	-	M	-	-	-	CHAP domain
EDGOKLHD_03308	1.07e-91	-	-	-	L	-	-	-	manually curated
EDGOKLHD_03309	3.6e-36	-	-	-	M	-	-	-	CHAP domain
EDGOKLHD_03311	5.77e-115	-	-	-	S	-	-	-	COG0433 Predicted ATPase
EDGOKLHD_03315	1.11e-118	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
EDGOKLHD_03316	6.14e-174	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
EDGOKLHD_03318	2.83e-26	-	-	-	-	-	-	-	-
EDGOKLHD_03319	3.53e-293	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
EDGOKLHD_03320	5.06e-49	-	-	-	-	-	-	-	-
EDGOKLHD_03321	2.19e-45	-	-	-	-	-	-	-	-
EDGOKLHD_03322	1.04e-62	-	-	-	KLT	-	-	-	serine threonine protein kinase
EDGOKLHD_03323	2.64e-124	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
EDGOKLHD_03327	3.46e-34	XK27_09800	-	-	I	-	-	-	Acyltransferase family
EDGOKLHD_03328	1.67e-123	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
EDGOKLHD_03329	2.8e-213	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EDGOKLHD_03330	3.04e-53	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EDGOKLHD_03331	4.77e-128	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EDGOKLHD_03333	1.96e-183	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
EDGOKLHD_03335	4.22e-51	-	-	-	L	-	-	-	Transposase DDE domain
EDGOKLHD_03336	4.9e-39	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
EDGOKLHD_03337	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
EDGOKLHD_03338	1.03e-55	-	-	-	-	-	-	-	-
EDGOKLHD_03339	1.69e-37	-	-	-	-	-	-	-	-
EDGOKLHD_03340	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
EDGOKLHD_03341	5.7e-79	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
EDGOKLHD_03342	2.7e-160	epsB	-	-	M	-	-	-	biosynthesis protein
EDGOKLHD_03343	5.82e-164	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
EDGOKLHD_03344	8.69e-177	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
EDGOKLHD_03345	1.39e-228	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
EDGOKLHD_03346	3.82e-156	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
EDGOKLHD_03347	3.37e-56	wcaA	-	-	M	-	-	-	Glycosyl transferase family 2
EDGOKLHD_03348	8.76e-07	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EDGOKLHD_03350	0.000644	icaA	2.4.1.212	GT2	M	ko:K00752,ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyltransferases, probably involved in cell wall biogenesis
EDGOKLHD_03351	1.45e-63	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
EDGOKLHD_03352	3.33e-105	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein