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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IOKFKOHM_00001	7.5e-282	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOKFKOHM_00002	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
IOKFKOHM_00003	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
IOKFKOHM_00004	6.53e-290	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOKFKOHM_00005	1.61e-126	-	-	-	S	-	-	-	YcxB-like protein
IOKFKOHM_00006	3.98e-206	ycxC	-	-	EG	-	-	-	EamA-like transporter family
IOKFKOHM_00007	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
IOKFKOHM_00008	2.02e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
IOKFKOHM_00009	8.71e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
IOKFKOHM_00010	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IOKFKOHM_00011	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IOKFKOHM_00012	1.44e-186	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IOKFKOHM_00013	9.2e-210	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
IOKFKOHM_00014	9.12e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IOKFKOHM_00015	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IOKFKOHM_00016	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
IOKFKOHM_00017	9.45e-104	yclD	-	-	-	-	-	-	-
IOKFKOHM_00018	1.07e-199	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
IOKFKOHM_00019	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
IOKFKOHM_00020	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
IOKFKOHM_00022	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IOKFKOHM_00023	2.99e-290	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
IOKFKOHM_00024	4.95e-249	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
IOKFKOHM_00025	4.82e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOKFKOHM_00026	4.5e-275	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
IOKFKOHM_00027	2.09e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_00028	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOKFKOHM_00029	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IOKFKOHM_00031	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IOKFKOHM_00033	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOKFKOHM_00034	2.2e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_00035	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_00036	3.8e-174	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_00037	5.72e-213	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
IOKFKOHM_00038	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
IOKFKOHM_00039	1.76e-199	ycnC	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00040	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IOKFKOHM_00041	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
IOKFKOHM_00042	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOKFKOHM_00043	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOKFKOHM_00044	3.97e-312	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOKFKOHM_00045	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOKFKOHM_00046	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
IOKFKOHM_00047	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_00048	1.14e-133	ycnI	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_00049	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
IOKFKOHM_00050	1.22e-137	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IOKFKOHM_00051	5.46e-74	-	-	-	-	-	-	-	-
IOKFKOHM_00052	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
IOKFKOHM_00053	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IOKFKOHM_00054	3.77e-269	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
IOKFKOHM_00055	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
IOKFKOHM_00056	2.66e-126	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOKFKOHM_00057	1.32e-24	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
IOKFKOHM_00058	2.68e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IOKFKOHM_00060	3.15e-176	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IOKFKOHM_00061	3.01e-178	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
IOKFKOHM_00062	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
IOKFKOHM_00063	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
IOKFKOHM_00064	2.8e-170	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
IOKFKOHM_00065	3.31e-237	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
IOKFKOHM_00066	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00067	1.2e-153	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
IOKFKOHM_00069	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
IOKFKOHM_00070	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
IOKFKOHM_00071	3.5e-219	ycsN	-	-	S	-	-	-	Oxidoreductase
IOKFKOHM_00072	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
IOKFKOHM_00073	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
IOKFKOHM_00074	1e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
IOKFKOHM_00075	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_00076	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
IOKFKOHM_00077	8.32e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOKFKOHM_00078	6.13e-100	ydaG	-	-	S	-	-	-	general stress protein
IOKFKOHM_00079	2.65e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IOKFKOHM_00080	5.19e-60	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
IOKFKOHM_00081	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IOKFKOHM_00082	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOKFKOHM_00083	3.31e-262	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IOKFKOHM_00084	2.58e-192	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IOKFKOHM_00085	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
IOKFKOHM_00086	1.12e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IOKFKOHM_00087	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
IOKFKOHM_00088	0.0	ydaO	-	-	E	-	-	-	amino acid
IOKFKOHM_00089	5.12e-101	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IOKFKOHM_00090	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOKFKOHM_00092	1.84e-34	-	-	-	-	-	-	-	-
IOKFKOHM_00093	2.18e-90	sdpB	-	-	S	-	-	-	Protein conserved in bacteria
IOKFKOHM_00095	6.14e-53	-	-	-	-	-	-	-	-
IOKFKOHM_00096	7.87e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOKFKOHM_00097	1.67e-42	ydaS	-	-	S	-	-	-	membrane
IOKFKOHM_00098	7.54e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IOKFKOHM_00099	4.3e-190	ydbA	-	-	P	-	-	-	EcsC protein family
IOKFKOHM_00100	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
IOKFKOHM_00101	3.07e-75	ydbB	-	-	G	-	-	-	Cupin domain
IOKFKOHM_00102	3.13e-83	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
IOKFKOHM_00103	6.41e-197	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
IOKFKOHM_00104	3.66e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IOKFKOHM_00105	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IOKFKOHM_00106	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IOKFKOHM_00107	7.33e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOKFKOHM_00108	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
IOKFKOHM_00109	2.28e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_00110	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOKFKOHM_00111	9.32e-70	ydbL	-	-	-	-	-	-	-
IOKFKOHM_00112	2.49e-278	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
IOKFKOHM_00113	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
IOKFKOHM_00115	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOKFKOHM_00116	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
IOKFKOHM_00117	1.25e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IOKFKOHM_00118	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOKFKOHM_00119	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOKFKOHM_00120	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IOKFKOHM_00121	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
IOKFKOHM_00122	5.12e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
IOKFKOHM_00123	1.6e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOKFKOHM_00124	6.62e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
IOKFKOHM_00125	1.77e-282	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOKFKOHM_00126	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IOKFKOHM_00127	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IOKFKOHM_00128	2.46e-183	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
IOKFKOHM_00129	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
IOKFKOHM_00130	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IOKFKOHM_00131	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
IOKFKOHM_00132	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
IOKFKOHM_00133	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IOKFKOHM_00134	3.12e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOKFKOHM_00135	7.57e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
IOKFKOHM_00136	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
IOKFKOHM_00137	2.17e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IOKFKOHM_00145	4.46e-153	-	-	-	E	-	-	-	amino acid
IOKFKOHM_00146	9.13e-135	ywqM	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00147	4.64e-95	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOKFKOHM_00148	2.33e-57	-	-	-	-	-	-	-	-
IOKFKOHM_00149	1.35e-169	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOKFKOHM_00152	1.54e-46	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IOKFKOHM_00153	6e-53	-	-	-	-	-	-	-	-
IOKFKOHM_00157	1e-144	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
IOKFKOHM_00158	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
IOKFKOHM_00159	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
IOKFKOHM_00160	2.79e-181	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOKFKOHM_00161	1.04e-211	-	-	-	K	-	-	-	AraC-like ligand binding domain
IOKFKOHM_00162	1.17e-222	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOKFKOHM_00163	7.88e-211	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
IOKFKOHM_00164	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOKFKOHM_00165	1.09e-276	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
IOKFKOHM_00166	7.89e-71	ydeH	-	-	-	-	-	-	-
IOKFKOHM_00167	2.25e-132	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
IOKFKOHM_00168	1.09e-143	-	-	-	-	-	-	-	-
IOKFKOHM_00169	2.4e-41	-	-	-	S	-	-	-	SNARE associated Golgi protein
IOKFKOHM_00170	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IOKFKOHM_00171	4.22e-111	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IOKFKOHM_00172	1.82e-194	ydeK	-	-	EG	-	-	-	-transporter
IOKFKOHM_00173	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOKFKOHM_00174	4.3e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
IOKFKOHM_00175	2.81e-134	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
IOKFKOHM_00176	1.02e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IOKFKOHM_00177	1.32e-193	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOKFKOHM_00178	2.92e-90	ydeP	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00179	1e-144	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
IOKFKOHM_00180	1.96e-257	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IOKFKOHM_00181	9.96e-135	ydeS	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00182	1.05e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
IOKFKOHM_00183	1.75e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IOKFKOHM_00184	1.5e-186	-	-	-	J	-	-	-	GNAT acetyltransferase
IOKFKOHM_00185	4.34e-191	-	-	-	EG	-	-	-	EamA-like transporter family
IOKFKOHM_00186	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOKFKOHM_00187	1.54e-232	-	4.1.1.86	-	E	ko:K13745	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
IOKFKOHM_00188	2.34e-148	ydfE	-	-	S	-	-	-	Flavin reductase like domain
IOKFKOHM_00189	1.5e-158	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOKFKOHM_00190	3.92e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IOKFKOHM_00192	1.08e-248	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_00193	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOKFKOHM_00194	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
IOKFKOHM_00195	4.39e-148	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IOKFKOHM_00196	5.86e-187	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IOKFKOHM_00197	8.64e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOKFKOHM_00198	9.88e-145	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
IOKFKOHM_00199	1.11e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IOKFKOHM_00200	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
IOKFKOHM_00201	1.04e-71	ydfQ	-	-	CO	-	-	-	Thioredoxin
IOKFKOHM_00202	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IOKFKOHM_00203	5.33e-39	-	-	-	-	-	-	-	-
IOKFKOHM_00205	1.01e-70	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOKFKOHM_00206	1.23e-40	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOKFKOHM_00207	7.36e-159	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOKFKOHM_00208	2.57e-89	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IOKFKOHM_00209	1.53e-47	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IOKFKOHM_00210	8.97e-47	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IOKFKOHM_00211	4.92e-127	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOKFKOHM_00212	2.01e-70	-	-	-	S	-	-	-	DoxX-like family
IOKFKOHM_00213	3.15e-108	yycN	-	-	K	-	-	-	Acetyltransferase
IOKFKOHM_00214	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
IOKFKOHM_00215	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IOKFKOHM_00216	6.94e-117	-	-	-	S	-	-	-	DinB family
IOKFKOHM_00217	8.12e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_00218	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
IOKFKOHM_00219	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
IOKFKOHM_00220	3.29e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IOKFKOHM_00221	5.72e-265	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
IOKFKOHM_00222	1.45e-154	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOKFKOHM_00223	2.14e-157	ydhC	-	-	K	-	-	-	FCD
IOKFKOHM_00224	2.1e-308	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
IOKFKOHM_00225	9.21e-288	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IOKFKOHM_00226	4.11e-161	-	-	-	-	-	-	-	-
IOKFKOHM_00227	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IOKFKOHM_00228	2.64e-86	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
IOKFKOHM_00230	1.8e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOKFKOHM_00231	3.15e-230	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOKFKOHM_00232	2.59e-126	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
IOKFKOHM_00233	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IOKFKOHM_00234	1.88e-63	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_00235	3.39e-67	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_00236	1.53e-303	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOKFKOHM_00237	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOKFKOHM_00238	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IOKFKOHM_00239	3.34e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
IOKFKOHM_00240	5.09e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IOKFKOHM_00241	3.91e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
IOKFKOHM_00242	3.44e-202	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
IOKFKOHM_00245	6.66e-52	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
IOKFKOHM_00246	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
IOKFKOHM_00247	2.16e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOKFKOHM_00248	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
IOKFKOHM_00249	4.31e-123	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_00250	1.3e-60	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
IOKFKOHM_00251	5.89e-42	-	-	-	-	-	-	-	-
IOKFKOHM_00252	2.55e-38	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
IOKFKOHM_00253	5.76e-211	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_00254	1.81e-175	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOKFKOHM_00255	3.52e-274	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOKFKOHM_00256	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IOKFKOHM_00257	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IOKFKOHM_00258	8.94e-28	yxzF	-	-	-	-	-	-	-
IOKFKOHM_00259	2.22e-278	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IOKFKOHM_00260	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
IOKFKOHM_00261	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOKFKOHM_00262	8.33e-68	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_00263	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IOKFKOHM_00264	1.25e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IOKFKOHM_00265	2.91e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_00266	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOKFKOHM_00267	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOKFKOHM_00268	4.44e-295	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
IOKFKOHM_00269	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOKFKOHM_00270	5.1e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IOKFKOHM_00271	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
IOKFKOHM_00272	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
IOKFKOHM_00273	1.05e-295	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOKFKOHM_00274	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00275	2e-152	ywaF	-	-	S	-	-	-	Integral membrane protein
IOKFKOHM_00276	5.37e-216	gspA	-	-	M	-	-	-	General stress
IOKFKOHM_00277	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IOKFKOHM_00278	2.79e-310	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_00279	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOKFKOHM_00280	2.81e-316	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOKFKOHM_00281	1.69e-159	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
IOKFKOHM_00282	1.99e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
IOKFKOHM_00283	7.52e-283	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
IOKFKOHM_00284	3.13e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
IOKFKOHM_00285	1.45e-277	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
IOKFKOHM_00286	1.72e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
IOKFKOHM_00287	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IOKFKOHM_00288	1.1e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00289	1.8e-182	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOKFKOHM_00290	1.81e-148	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOKFKOHM_00291	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
IOKFKOHM_00292	6.92e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
IOKFKOHM_00293	3.1e-308	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
IOKFKOHM_00294	1.32e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IOKFKOHM_00295	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOKFKOHM_00296	2.13e-64	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
IOKFKOHM_00298	3.42e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
IOKFKOHM_00299	3.88e-76	gtcA	-	-	S	-	-	-	GtrA-like protein
IOKFKOHM_00300	2.54e-287	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOKFKOHM_00301	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IOKFKOHM_00302	5.11e-49	ydaS	-	-	S	-	-	-	membrane
IOKFKOHM_00303	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IOKFKOHM_00304	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IOKFKOHM_00305	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IOKFKOHM_00306	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IOKFKOHM_00307	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
IOKFKOHM_00308	3.69e-260	-	-	-	S	-	-	-	Acetyltransferase
IOKFKOHM_00309	8.89e-269	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IOKFKOHM_00310	2.31e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
IOKFKOHM_00311	5.71e-237	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOKFKOHM_00312	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOKFKOHM_00314	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IOKFKOHM_00315	2.79e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
IOKFKOHM_00316	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_00317	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IOKFKOHM_00318	6.19e-39	ywdA	-	-	-	-	-	-	-
IOKFKOHM_00319	2.21e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOKFKOHM_00320	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
IOKFKOHM_00321	2.71e-165	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOKFKOHM_00322	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOKFKOHM_00323	4.4e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
IOKFKOHM_00324	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
IOKFKOHM_00325	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
IOKFKOHM_00326	7.61e-114	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IOKFKOHM_00327	7.76e-185	spsA	-	-	M	-	-	-	Spore Coat
IOKFKOHM_00328	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
IOKFKOHM_00329	6.44e-285	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
IOKFKOHM_00330	5.75e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
IOKFKOHM_00331	1.13e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
IOKFKOHM_00332	1.09e-167	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
IOKFKOHM_00333	7.8e-238	spsG	-	-	M	-	-	-	Spore Coat
IOKFKOHM_00334	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOKFKOHM_00335	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOKFKOHM_00336	1.41e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOKFKOHM_00337	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
IOKFKOHM_00338	1.51e-100	-	-	-	-	-	-	-	-
IOKFKOHM_00339	4.97e-309	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOKFKOHM_00340	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IOKFKOHM_00341	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IOKFKOHM_00342	6.01e-315	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IOKFKOHM_00343	1.89e-275	ywfA	-	-	EGP	-	-	-	-transporter
IOKFKOHM_00344	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IOKFKOHM_00345	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IOKFKOHM_00346	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_00347	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IOKFKOHM_00348	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IOKFKOHM_00349	3.66e-296	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IOKFKOHM_00350	3.93e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
IOKFKOHM_00351	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
IOKFKOHM_00352	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
IOKFKOHM_00353	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_00354	4.16e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IOKFKOHM_00355	2.39e-199	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
IOKFKOHM_00356	5.39e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
IOKFKOHM_00357	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
IOKFKOHM_00358	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
IOKFKOHM_00359	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
IOKFKOHM_00360	3.15e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00361	3.06e-300	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
IOKFKOHM_00363	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOKFKOHM_00364	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00365	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
IOKFKOHM_00366	5.45e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
IOKFKOHM_00367	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
IOKFKOHM_00368	2.1e-64	-	-	-	-	-	-	-	-
IOKFKOHM_00369	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IOKFKOHM_00370	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IOKFKOHM_00371	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IOKFKOHM_00372	2.76e-65	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
IOKFKOHM_00374	9.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IOKFKOHM_00375	9.47e-275	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
IOKFKOHM_00376	0.0	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
IOKFKOHM_00378	1.28e-312	-	-	-	L	-	-	-	Peptidase, M16
IOKFKOHM_00379	6.64e-274	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
IOKFKOHM_00380	1.98e-296	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
IOKFKOHM_00381	3.53e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOKFKOHM_00383	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
IOKFKOHM_00384	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
IOKFKOHM_00385	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_00386	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IOKFKOHM_00387	8.44e-274	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IOKFKOHM_00388	2.3e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
IOKFKOHM_00389	1.45e-176	ywiC	-	-	S	-	-	-	YwiC-like protein
IOKFKOHM_00390	5.02e-110	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
IOKFKOHM_00391	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOKFKOHM_00392	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
IOKFKOHM_00393	2.77e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
IOKFKOHM_00394	2.06e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
IOKFKOHM_00395	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOKFKOHM_00396	9.8e-37	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOKFKOHM_00397	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOKFKOHM_00398	5.49e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
IOKFKOHM_00399	1.4e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IOKFKOHM_00400	4.55e-285	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IOKFKOHM_00401	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
IOKFKOHM_00402	3.48e-268	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
IOKFKOHM_00403	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOKFKOHM_00404	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOKFKOHM_00405	6.41e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
IOKFKOHM_00406	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
IOKFKOHM_00407	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
IOKFKOHM_00408	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOKFKOHM_00409	3.74e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOKFKOHM_00410	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
IOKFKOHM_00411	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOKFKOHM_00412	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IOKFKOHM_00413	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IOKFKOHM_00414	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IOKFKOHM_00415	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IOKFKOHM_00416	1.72e-116	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IOKFKOHM_00417	3.99e-88	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOKFKOHM_00418	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOKFKOHM_00419	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOKFKOHM_00421	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IOKFKOHM_00422	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
IOKFKOHM_00423	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
IOKFKOHM_00424	7.37e-251	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOKFKOHM_00425	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IOKFKOHM_00426	1.58e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOKFKOHM_00427	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
IOKFKOHM_00428	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IOKFKOHM_00429	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOKFKOHM_00430	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOKFKOHM_00431	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
IOKFKOHM_00432	2.47e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IOKFKOHM_00433	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOKFKOHM_00434	5.03e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOKFKOHM_00435	7.94e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOKFKOHM_00436	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOKFKOHM_00437	1.28e-194	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOKFKOHM_00438	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOKFKOHM_00439	3.89e-72	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IOKFKOHM_00440	7.16e-114	ywmA	-	-	-	-	-	-	-
IOKFKOHM_00441	4.54e-45	ywzB	-	-	S	-	-	-	membrane
IOKFKOHM_00442	3.26e-172	ywmB	-	-	S	-	-	-	TATA-box binding
IOKFKOHM_00443	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOKFKOHM_00444	3.05e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
IOKFKOHM_00445	1.28e-155	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IOKFKOHM_00446	5.87e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IOKFKOHM_00448	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IOKFKOHM_00449	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IOKFKOHM_00450	6.22e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IOKFKOHM_00451	1.21e-109	ywmF	-	-	S	-	-	-	Peptidase M50
IOKFKOHM_00452	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
IOKFKOHM_00453	3.34e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
IOKFKOHM_00454	3.2e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
IOKFKOHM_00455	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IOKFKOHM_00456	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00457	1.19e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IOKFKOHM_00458	3.55e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IOKFKOHM_00459	4.85e-184	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
IOKFKOHM_00460	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOKFKOHM_00461	1.05e-91	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
IOKFKOHM_00462	6.7e-234	-	-	-	M	-	-	-	NeuB family
IOKFKOHM_00463	6.95e-21	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IOKFKOHM_00464	3.65e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
IOKFKOHM_00465	2.63e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IOKFKOHM_00466	2.7e-94	ywnJ	-	-	S	-	-	-	VanZ like family
IOKFKOHM_00467	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
IOKFKOHM_00468	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
IOKFKOHM_00469	1.12e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
IOKFKOHM_00470	8.71e-102	-	-	-	-	-	-	-	-
IOKFKOHM_00471	3e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
IOKFKOHM_00472	1.54e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
IOKFKOHM_00473	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
IOKFKOHM_00474	1.14e-309	ywoF	-	-	P	-	-	-	Right handed beta helix region
IOKFKOHM_00475	1.12e-268	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_00476	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
IOKFKOHM_00477	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
IOKFKOHM_00478	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
IOKFKOHM_00479	1.45e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IOKFKOHM_00480	4.1e-182	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IOKFKOHM_00481	5.45e-257	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
IOKFKOHM_00482	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOKFKOHM_00483	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOKFKOHM_00484	1.72e-197	ywpD	-	-	T	-	-	-	Histidine kinase
IOKFKOHM_00485	1.55e-66	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOKFKOHM_00486	2.53e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
IOKFKOHM_00487	3.04e-87	ywpG	-	-	-	-	-	-	-
IOKFKOHM_00488	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IOKFKOHM_00489	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IOKFKOHM_00490	1.51e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IOKFKOHM_00491	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IOKFKOHM_00492	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
IOKFKOHM_00493	3.6e-25	-	-	-	-	-	-	-	-
IOKFKOHM_00494	8.84e-162	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IOKFKOHM_00495	8.57e-157	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IOKFKOHM_00496	1.44e-179	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
IOKFKOHM_00497	9.4e-313	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOKFKOHM_00498	2.42e-195	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
IOKFKOHM_00500	8.84e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
IOKFKOHM_00501	3.15e-265	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
IOKFKOHM_00502	2.5e-26	-	-	-	-	-	-	-	-
IOKFKOHM_00503	1.3e-23	-	-	-	-	-	-	-	-
IOKFKOHM_00504	4.93e-95	ywqJ	-	-	S	-	-	-	Pre-toxin TG
IOKFKOHM_00505	9.77e-48	-	-	-	S	ko:K11904,ko:K21493	ko03070,map03070	ko00000,ko00001,ko00002,ko01000,ko02044,ko02048	protein secretion by the type VII secretion system
IOKFKOHM_00507	2.88e-147	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IOKFKOHM_00508	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00509	1.44e-127	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
IOKFKOHM_00511	1.01e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
IOKFKOHM_00512	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
IOKFKOHM_00513	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IOKFKOHM_00514	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IOKFKOHM_00515	1.13e-70	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
IOKFKOHM_00516	5.94e-141	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IOKFKOHM_00517	1e-17	-	-	-	-	-	-	-	-
IOKFKOHM_00518	2.08e-265	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IOKFKOHM_00519	7.86e-162	cotB	-	-	-	ko:K06325	-	ko00000	-
IOKFKOHM_00520	4.33e-162	ywrJ	-	-	-	-	-	-	-
IOKFKOHM_00521	9.31e-279	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IOKFKOHM_00522	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
IOKFKOHM_00523	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IOKFKOHM_00524	1.51e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IOKFKOHM_00525	1.2e-123	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
IOKFKOHM_00526	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
IOKFKOHM_00527	1.97e-119	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
IOKFKOHM_00528	1.28e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
IOKFKOHM_00529	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOKFKOHM_00530	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IOKFKOHM_00531	6.55e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOKFKOHM_00532	6.18e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOKFKOHM_00533	4.12e-225	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IOKFKOHM_00534	2.08e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
IOKFKOHM_00535	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
IOKFKOHM_00536	1.1e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IOKFKOHM_00537	2.29e-29	ywtC	-	-	-	-	-	-	-
IOKFKOHM_00538	1.37e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IOKFKOHM_00539	5.71e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IOKFKOHM_00540	1.18e-176	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00541	8.19e-316	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOKFKOHM_00542	2.52e-263	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IOKFKOHM_00543	1.73e-247	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IOKFKOHM_00544	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IOKFKOHM_00545	3.88e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IOKFKOHM_00546	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOKFKOHM_00547	1.5e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOKFKOHM_00548	4.13e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOKFKOHM_00549	2.4e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
IOKFKOHM_00550	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOKFKOHM_00551	0.0	tagF2	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOKFKOHM_00554	3.02e-171	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
IOKFKOHM_00555	2.7e-204	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IOKFKOHM_00556	1.07e-14	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
IOKFKOHM_00557	1.64e-204	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOKFKOHM_00558	2.43e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOKFKOHM_00559	4.48e-22	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IOKFKOHM_00560	1.39e-15	-	-	-	-	-	-	-	-
IOKFKOHM_00561	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
IOKFKOHM_00562	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IOKFKOHM_00563	2.13e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IOKFKOHM_00564	1.28e-300	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOKFKOHM_00565	3.51e-256	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
IOKFKOHM_00566	8.18e-302	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOKFKOHM_00568	9.1e-315	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
IOKFKOHM_00569	9.78e-136	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
IOKFKOHM_00570	1.61e-175	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IOKFKOHM_00571	3.64e-291	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
IOKFKOHM_00572	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IOKFKOHM_00574	6.05e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_00577	1.03e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOKFKOHM_00581	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00582	6.47e-135	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
IOKFKOHM_00583	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IOKFKOHM_00584	2.92e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOKFKOHM_00585	1.24e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_00586	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IOKFKOHM_00587	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
IOKFKOHM_00588	2.26e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
IOKFKOHM_00589	3.7e-96	yvyF	-	-	S	-	-	-	flagellar protein
IOKFKOHM_00590	8.72e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
IOKFKOHM_00591	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
IOKFKOHM_00592	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
IOKFKOHM_00593	3.8e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
IOKFKOHM_00594	3.8e-89	yviE	-	-	-	-	-	-	-
IOKFKOHM_00595	1.68e-94	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IOKFKOHM_00596	2.58e-41	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IOKFKOHM_00597	2.33e-160	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IOKFKOHM_00598	3.03e-74	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
IOKFKOHM_00599	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IOKFKOHM_00600	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
IOKFKOHM_00601	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
IOKFKOHM_00602	2.46e-67	-	-	-	-	-	-	-	-
IOKFKOHM_00603	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOKFKOHM_00604	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOKFKOHM_00605	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOKFKOHM_00606	1.86e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOKFKOHM_00607	2.56e-72	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IOKFKOHM_00608	8.68e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
IOKFKOHM_00609	1.1e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IOKFKOHM_00610	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IOKFKOHM_00611	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
IOKFKOHM_00612	9.09e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOKFKOHM_00613	3.03e-295	yvkA	-	-	P	-	-	-	-transporter
IOKFKOHM_00614	1.66e-130	yvkB	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00615	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
IOKFKOHM_00616	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_00617	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOKFKOHM_00618	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOKFKOHM_00619	1.68e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IOKFKOHM_00620	2.25e-45	yvkN	-	-	-	-	-	-	-
IOKFKOHM_00621	3.3e-64	yvlA	-	-	-	-	-	-	-
IOKFKOHM_00622	9.59e-220	yvlB	-	-	S	-	-	-	Putative adhesin
IOKFKOHM_00623	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IOKFKOHM_00624	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
IOKFKOHM_00625	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOKFKOHM_00626	6.2e-114	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_00627	8.35e-176	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
IOKFKOHM_00628	2.45e-288	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOKFKOHM_00629	1.36e-92	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_00630	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
IOKFKOHM_00631	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
IOKFKOHM_00632	8.99e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOKFKOHM_00633	5.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOKFKOHM_00634	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOKFKOHM_00635	1.29e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOKFKOHM_00636	3.05e-210	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
IOKFKOHM_00637	1.06e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IOKFKOHM_00638	3.58e-119	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IOKFKOHM_00639	6.63e-155	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
IOKFKOHM_00640	2.14e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
IOKFKOHM_00641	2.42e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IOKFKOHM_00642	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IOKFKOHM_00643	1.81e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOKFKOHM_00644	1.36e-136	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IOKFKOHM_00645	1.15e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOKFKOHM_00646	4.61e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IOKFKOHM_00647	3.8e-174	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOKFKOHM_00648	2.41e-142	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
IOKFKOHM_00649	3.7e-111	-	-	-	-	-	-	-	-
IOKFKOHM_00650	0.0	-	-	-	-	-	-	-	-
IOKFKOHM_00652	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IOKFKOHM_00653	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
IOKFKOHM_00654	1.89e-185	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
IOKFKOHM_00655	1.18e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOKFKOHM_00656	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IOKFKOHM_00657	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IOKFKOHM_00658	2.73e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IOKFKOHM_00659	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IOKFKOHM_00660	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
IOKFKOHM_00661	2.3e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
IOKFKOHM_00662	3.24e-44	-	-	-	-	-	-	-	-
IOKFKOHM_00663	3.16e-170	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_00664	1.96e-251	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IOKFKOHM_00665	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_00666	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IOKFKOHM_00667	2.7e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOKFKOHM_00668	8.79e-136	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IOKFKOHM_00669	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IOKFKOHM_00670	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IOKFKOHM_00671	3.89e-79	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IOKFKOHM_00672	3.06e-27	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IOKFKOHM_00673	4.42e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00674	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
IOKFKOHM_00675	1.63e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IOKFKOHM_00676	7.94e-307	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IOKFKOHM_00677	2.79e-189	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IOKFKOHM_00678	4.3e-197	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IOKFKOHM_00679	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
IOKFKOHM_00680	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IOKFKOHM_00681	3.5e-152	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOKFKOHM_00682	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOKFKOHM_00684	7.83e-96	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
IOKFKOHM_00685	4.21e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
IOKFKOHM_00686	1.05e-66	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IOKFKOHM_00687	2.75e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00688	0.0	ybeC	-	-	E	-	-	-	amino acid
IOKFKOHM_00689	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOKFKOHM_00690	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
IOKFKOHM_00691	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
IOKFKOHM_00692	8.37e-161	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IOKFKOHM_00693	7.42e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
IOKFKOHM_00694	8.97e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IOKFKOHM_00696	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
IOKFKOHM_00697	3.57e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
IOKFKOHM_00698	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IOKFKOHM_00699	2.28e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IOKFKOHM_00700	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IOKFKOHM_00701	2.83e-284	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
IOKFKOHM_00702	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOKFKOHM_00703	2.06e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOKFKOHM_00704	1.03e-263	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
IOKFKOHM_00705	1.22e-248	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IOKFKOHM_00706	3.16e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
IOKFKOHM_00707	1.86e-243	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOKFKOHM_00708	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOKFKOHM_00709	3.72e-138	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IOKFKOHM_00710	1.15e-80	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IOKFKOHM_00711	5.25e-279	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IOKFKOHM_00712	1.03e-238	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
IOKFKOHM_00713	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
IOKFKOHM_00714	2.36e-304	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IOKFKOHM_00715	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IOKFKOHM_00716	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
IOKFKOHM_00717	2.33e-235	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_00718	4.62e-292	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IOKFKOHM_00719	5.29e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IOKFKOHM_00720	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IOKFKOHM_00721	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
IOKFKOHM_00722	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
IOKFKOHM_00723	5.07e-264	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
IOKFKOHM_00724	4.9e-199	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
IOKFKOHM_00725	1.15e-66	-	-	-	S	-	-	-	ASCH
IOKFKOHM_00726	3.23e-178	-	-	-	M	-	-	-	-acetyltransferase
IOKFKOHM_00727	8.25e-33	-	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	AAA domain
IOKFKOHM_00728	2.22e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
IOKFKOHM_00729	5.85e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IOKFKOHM_00730	5.39e-252	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_00731	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOKFKOHM_00732	4.23e-42	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOKFKOHM_00733	3.88e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
IOKFKOHM_00734	9.08e-175	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IOKFKOHM_00735	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IOKFKOHM_00736	4.15e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IOKFKOHM_00737	5.18e-250	-	-	-	S	-	-	-	Glycosyl hydrolase
IOKFKOHM_00738	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOKFKOHM_00739	1.6e-197	yvbV	-	-	EG	-	-	-	EamA-like transporter family
IOKFKOHM_00740	4.9e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00741	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOKFKOHM_00742	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
IOKFKOHM_00743	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOKFKOHM_00744	5.69e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IOKFKOHM_00745	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOKFKOHM_00746	2.3e-276	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IOKFKOHM_00747	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOKFKOHM_00748	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
IOKFKOHM_00749	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOKFKOHM_00750	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
IOKFKOHM_00751	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IOKFKOHM_00752	9.3e-156	yvbI	-	-	M	-	-	-	Membrane
IOKFKOHM_00753	2.96e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
IOKFKOHM_00754	7.95e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
IOKFKOHM_00755	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IOKFKOHM_00756	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IOKFKOHM_00757	4.63e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IOKFKOHM_00758	1.23e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOKFKOHM_00759	1.13e-135	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IOKFKOHM_00760	3.28e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IOKFKOHM_00761	1.73e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IOKFKOHM_00762	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IOKFKOHM_00763	1.13e-218	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOKFKOHM_00764	9.2e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IOKFKOHM_00765	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOKFKOHM_00766	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
IOKFKOHM_00767	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IOKFKOHM_00768	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
IOKFKOHM_00769	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
IOKFKOHM_00770	5.73e-196	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
IOKFKOHM_00771	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
IOKFKOHM_00772	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
IOKFKOHM_00773	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOKFKOHM_00774	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IOKFKOHM_00776	3.25e-181	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_00777	9.98e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOKFKOHM_00778	3.52e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
IOKFKOHM_00779	5.79e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
IOKFKOHM_00780	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
IOKFKOHM_00781	2.08e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOKFKOHM_00782	1.99e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IOKFKOHM_00783	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
IOKFKOHM_00784	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
IOKFKOHM_00785	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IOKFKOHM_00786	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IOKFKOHM_00787	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
IOKFKOHM_00788	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
IOKFKOHM_00789	2.34e-139	yvgT	-	-	S	-	-	-	membrane
IOKFKOHM_00791	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOKFKOHM_00792	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IOKFKOHM_00793	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IOKFKOHM_00794	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
IOKFKOHM_00795	7.97e-113	yvgO	-	-	-	-	-	-	-
IOKFKOHM_00796	6.19e-201	yvgN	-	-	S	-	-	-	reductase
IOKFKOHM_00797	1.95e-150	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
IOKFKOHM_00798	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
IOKFKOHM_00799	4.91e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
IOKFKOHM_00800	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
IOKFKOHM_00801	1.96e-108	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IOKFKOHM_00802	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
IOKFKOHM_00803	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IOKFKOHM_00805	2.57e-224	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOKFKOHM_00806	4.04e-235	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_00807	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_00808	9.78e-190	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOKFKOHM_00809	3.28e-227	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
IOKFKOHM_00810	1.33e-158	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_00811	1.12e-270	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IOKFKOHM_00812	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
IOKFKOHM_00813	4.39e-290	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IOKFKOHM_00814	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
IOKFKOHM_00815	6.74e-126	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
IOKFKOHM_00816	5.07e-32	-	-	-	-	-	-	-	-
IOKFKOHM_00817	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_00818	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
IOKFKOHM_00819	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
IOKFKOHM_00820	1.23e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_00821	8.18e-216	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IOKFKOHM_00822	3.29e-237	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_00823	4.66e-312	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IOKFKOHM_00824	5.32e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
IOKFKOHM_00825	1.13e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_00826	5.07e-81	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
IOKFKOHM_00827	2.34e-141	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IOKFKOHM_00828	8.15e-172	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IOKFKOHM_00829	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
IOKFKOHM_00830	3.34e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_00831	1.56e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOKFKOHM_00832	3.33e-247	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
IOKFKOHM_00833	8.3e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IOKFKOHM_00834	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IOKFKOHM_00835	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
IOKFKOHM_00836	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOKFKOHM_00837	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00838	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_00839	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_00840	2.26e-304	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOKFKOHM_00841	1.07e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
IOKFKOHM_00842	1.06e-194	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_00843	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
IOKFKOHM_00844	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
IOKFKOHM_00845	8.74e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOKFKOHM_00846	3.99e-53	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
IOKFKOHM_00847	5.68e-202	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
IOKFKOHM_00848	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_00849	4.86e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
IOKFKOHM_00850	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
IOKFKOHM_00851	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
IOKFKOHM_00852	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
IOKFKOHM_00853	2.23e-54	-	-	-	-	-	-	-	-
IOKFKOHM_00854	2.84e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IOKFKOHM_00855	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
IOKFKOHM_00856	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
IOKFKOHM_00857	5.45e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
IOKFKOHM_00858	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IOKFKOHM_00859	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IOKFKOHM_00860	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IOKFKOHM_00861	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
IOKFKOHM_00862	5.36e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
IOKFKOHM_00863	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
IOKFKOHM_00864	1.78e-73	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
IOKFKOHM_00865	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOKFKOHM_00866	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
IOKFKOHM_00867	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IOKFKOHM_00868	5.44e-81	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IOKFKOHM_00869	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IOKFKOHM_00870	6.1e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
IOKFKOHM_00871	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOKFKOHM_00872	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
IOKFKOHM_00873	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
IOKFKOHM_00874	7.18e-86	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOKFKOHM_00875	3.35e-56	-	-	-	-	-	-	-	-
IOKFKOHM_00877	4.87e-260	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
IOKFKOHM_00878	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
IOKFKOHM_00879	2.24e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IOKFKOHM_00880	3.9e-305	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IOKFKOHM_00881	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOKFKOHM_00882	5.57e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IOKFKOHM_00883	1.12e-207	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
IOKFKOHM_00884	7.46e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IOKFKOHM_00885	2.42e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOKFKOHM_00886	6.53e-218	bsn	-	-	L	-	-	-	Ribonuclease
IOKFKOHM_00887	1.18e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IOKFKOHM_00888	3.32e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IOKFKOHM_00889	7.49e-236	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IOKFKOHM_00890	4.18e-141	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
IOKFKOHM_00891	2.76e-184	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IOKFKOHM_00892	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IOKFKOHM_00893	1.7e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IOKFKOHM_00894	5.98e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IOKFKOHM_00895	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IOKFKOHM_00896	4.72e-285	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IOKFKOHM_00897	1.05e-293	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
IOKFKOHM_00898	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
IOKFKOHM_00899	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IOKFKOHM_00900	2.72e-82	yunG	-	-	-	-	-	-	-
IOKFKOHM_00901	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
IOKFKOHM_00902	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOKFKOHM_00903	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOKFKOHM_00904	3.41e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
IOKFKOHM_00905	4.25e-172	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
IOKFKOHM_00906	7.63e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
IOKFKOHM_00907	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IOKFKOHM_00908	1.29e-142	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOKFKOHM_00909	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_00910	1.61e-97	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
IOKFKOHM_00911	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOKFKOHM_00912	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IOKFKOHM_00913	1.55e-253	yutH	-	-	S	-	-	-	Spore coat protein
IOKFKOHM_00914	2.37e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IOKFKOHM_00915	1.05e-250	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IOKFKOHM_00916	4.96e-219	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOKFKOHM_00917	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
IOKFKOHM_00918	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
IOKFKOHM_00919	6.61e-75	yuzD	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_00920	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOKFKOHM_00921	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
IOKFKOHM_00922	1.79e-269	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOKFKOHM_00923	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOKFKOHM_00924	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
IOKFKOHM_00926	3.98e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOKFKOHM_00927	4.71e-148	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
IOKFKOHM_00928	6.4e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOKFKOHM_00930	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
IOKFKOHM_00931	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOKFKOHM_00932	2.3e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
IOKFKOHM_00933	1.49e-147	yuiC	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_00934	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
IOKFKOHM_00935	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IOKFKOHM_00936	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
IOKFKOHM_00937	2.05e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
IOKFKOHM_00938	6.78e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
IOKFKOHM_00939	5.17e-212	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
IOKFKOHM_00940	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_00941	1.22e-289	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IOKFKOHM_00942	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
IOKFKOHM_00943	4.47e-228	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
IOKFKOHM_00944	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOKFKOHM_00945	1.66e-46	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
IOKFKOHM_00946	1.99e-167	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
IOKFKOHM_00947	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IOKFKOHM_00948	1.71e-291	yukF	-	-	QT	-	-	-	Transcriptional regulator
IOKFKOHM_00949	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
IOKFKOHM_00950	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
IOKFKOHM_00951	1.93e-267	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
IOKFKOHM_00952	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOKFKOHM_00953	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
IOKFKOHM_00954	4.37e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
IOKFKOHM_00955	6.1e-171	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_00956	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IOKFKOHM_00957	3.97e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
IOKFKOHM_00958	4.72e-245	yueF	-	-	S	-	-	-	transporter activity
IOKFKOHM_00959	2.05e-42	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
IOKFKOHM_00960	1.34e-51	yueH	-	-	S	-	-	-	YueH-like protein
IOKFKOHM_00961	2.19e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IOKFKOHM_00962	1.56e-132	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
IOKFKOHM_00963	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOKFKOHM_00964	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
IOKFKOHM_00965	2.19e-09	yuzC	-	-	-	-	-	-	-
IOKFKOHM_00966	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
IOKFKOHM_00967	2.85e-182	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
IOKFKOHM_00969	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_00970	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOKFKOHM_00971	7.81e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
IOKFKOHM_00972	9.92e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
IOKFKOHM_00973	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOKFKOHM_00974	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOKFKOHM_00975	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOKFKOHM_00976	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOKFKOHM_00977	8.95e-90	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOKFKOHM_00978	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IOKFKOHM_00979	1.42e-21	-	-	-	-	-	-	-	-
IOKFKOHM_00980	7.99e-309	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
IOKFKOHM_00981	9.9e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOKFKOHM_00982	5.25e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOKFKOHM_00983	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_00984	1.28e-253	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
IOKFKOHM_00985	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IOKFKOHM_00986	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IOKFKOHM_00987	1.2e-112	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
IOKFKOHM_00988	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_00989	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
IOKFKOHM_00990	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
IOKFKOHM_00992	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
IOKFKOHM_00993	1.02e-90	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
IOKFKOHM_00994	1.06e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_00995	6.7e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IOKFKOHM_00996	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
IOKFKOHM_00997	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
IOKFKOHM_00998	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_00999	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
IOKFKOHM_01000	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IOKFKOHM_01001	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
IOKFKOHM_01002	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
IOKFKOHM_01003	9.22e-290	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
IOKFKOHM_01004	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IOKFKOHM_01006	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
IOKFKOHM_01007	8.37e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
IOKFKOHM_01008	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
IOKFKOHM_01009	1.58e-50	-	-	-	-	-	-	-	-
IOKFKOHM_01010	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
IOKFKOHM_01011	1.03e-299	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOKFKOHM_01012	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IOKFKOHM_01013	2.46e-93	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
IOKFKOHM_01014	5e-48	-	-	-	-	-	-	-	-
IOKFKOHM_01015	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IOKFKOHM_01016	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOKFKOHM_01017	2.29e-295	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOKFKOHM_01018	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOKFKOHM_01019	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOKFKOHM_01021	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
IOKFKOHM_01022	2.87e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IOKFKOHM_01023	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IOKFKOHM_01024	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
IOKFKOHM_01025	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
IOKFKOHM_01026	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IOKFKOHM_01027	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
IOKFKOHM_01028	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOKFKOHM_01030	6.82e-114	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
IOKFKOHM_01031	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
IOKFKOHM_01032	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOKFKOHM_01033	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
IOKFKOHM_01034	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
IOKFKOHM_01035	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IOKFKOHM_01036	5.83e-118	yuaB	-	-	-	-	-	-	-
IOKFKOHM_01037	2.9e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
IOKFKOHM_01038	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOKFKOHM_01039	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
IOKFKOHM_01040	5.8e-137	yuaD	-	-	-	-	-	-	-
IOKFKOHM_01041	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
IOKFKOHM_01042	3.39e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
IOKFKOHM_01043	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
IOKFKOHM_01044	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
IOKFKOHM_01045	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IOKFKOHM_01046	1.12e-67	xkdM	-	-	S	-	-	-	Phage tail tube protein
IOKFKOHM_01048	1.58e-88	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
IOKFKOHM_01049	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
IOKFKOHM_01050	3.12e-154	xkdP	-	-	S	-	-	-	Lysin motif
IOKFKOHM_01051	1.81e-225	xkdQ	-	-	G	-	-	-	NLP P60 protein
IOKFKOHM_01052	4.54e-48	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
IOKFKOHM_01053	1.75e-86	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IOKFKOHM_01054	3.86e-238	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IOKFKOHM_01055	9.55e-127	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IOKFKOHM_01056	8.29e-52	-	-	-	-	-	-	-	-
IOKFKOHM_01057	3.15e-257	-	-	-	-	-	-	-	-
IOKFKOHM_01058	1.01e-73	xkdW	-	-	S	-	-	-	XkdW protein
IOKFKOHM_01059	7.59e-21	-	-	-	-	-	-	-	-
IOKFKOHM_01060	5.93e-205	xepA	-	-	-	-	-	-	-
IOKFKOHM_01061	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
IOKFKOHM_01062	1.11e-172	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IOKFKOHM_01065	4.4e-132	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
IOKFKOHM_01066	0.0	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IOKFKOHM_01069	1.23e-119	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOKFKOHM_01070	1.7e-187	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
IOKFKOHM_01071	2.17e-72	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
IOKFKOHM_01072	3.34e-91	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOKFKOHM_01073	1.18e-231	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
IOKFKOHM_01074	9.82e-101	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
IOKFKOHM_01075	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
IOKFKOHM_01076	1.1e-72	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOKFKOHM_01077	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IOKFKOHM_01078	7.4e-168	-	-	-	-	-	-	-	-
IOKFKOHM_01079	4.23e-214	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
IOKFKOHM_01080	1.62e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
IOKFKOHM_01081	5.03e-178	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IOKFKOHM_01082	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOKFKOHM_01084	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
IOKFKOHM_01085	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IOKFKOHM_01086	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOKFKOHM_01087	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
IOKFKOHM_01088	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOKFKOHM_01089	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IOKFKOHM_01090	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOKFKOHM_01091	6.35e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
IOKFKOHM_01092	4.46e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOKFKOHM_01093	3.69e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
IOKFKOHM_01094	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IOKFKOHM_01095	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IOKFKOHM_01096	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
IOKFKOHM_01097	2.35e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IOKFKOHM_01098	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IOKFKOHM_01099	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IOKFKOHM_01100	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
IOKFKOHM_01101	2.37e-68	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
IOKFKOHM_01102	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOKFKOHM_01103	1.68e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IOKFKOHM_01104	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOKFKOHM_01105	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOKFKOHM_01106	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IOKFKOHM_01107	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOKFKOHM_01108	2.29e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
IOKFKOHM_01109	6.85e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOKFKOHM_01110	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
IOKFKOHM_01111	3.26e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
IOKFKOHM_01112	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IOKFKOHM_01113	4.53e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
IOKFKOHM_01114	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
IOKFKOHM_01115	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
IOKFKOHM_01116	3.13e-79	yqfB	-	-	-	-	-	-	-
IOKFKOHM_01117	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
IOKFKOHM_01118	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
IOKFKOHM_01119	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
IOKFKOHM_01121	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
IOKFKOHM_01122	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOKFKOHM_01123	1.16e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IOKFKOHM_01124	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IOKFKOHM_01125	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOKFKOHM_01126	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
IOKFKOHM_01127	1.76e-185	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IOKFKOHM_01128	4.92e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IOKFKOHM_01129	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IOKFKOHM_01130	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
IOKFKOHM_01131	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOKFKOHM_01132	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
IOKFKOHM_01133	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOKFKOHM_01134	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOKFKOHM_01135	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IOKFKOHM_01136	6.9e-150	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IOKFKOHM_01137	1.79e-267	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOKFKOHM_01138	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IOKFKOHM_01139	1.17e-52	yqfQ	-	-	S	-	-	-	YqfQ-like protein
IOKFKOHM_01140	5.42e-311	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOKFKOHM_01141	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOKFKOHM_01142	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
IOKFKOHM_01143	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOKFKOHM_01144	7.07e-106	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
IOKFKOHM_01145	6.79e-141	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
IOKFKOHM_01146	2.04e-81	yqfX	-	-	S	-	-	-	membrane
IOKFKOHM_01147	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IOKFKOHM_01148	1.64e-62	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
IOKFKOHM_01149	1.58e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IOKFKOHM_01150	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
IOKFKOHM_01151	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
IOKFKOHM_01152	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
IOKFKOHM_01153	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IOKFKOHM_01154	1.76e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IOKFKOHM_01155	4.11e-202	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IOKFKOHM_01156	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IOKFKOHM_01157	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOKFKOHM_01158	9.06e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOKFKOHM_01159	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
IOKFKOHM_01160	3.42e-68	yqzD	-	-	-	-	-	-	-
IOKFKOHM_01162	5.82e-250	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
IOKFKOHM_01163	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IOKFKOHM_01164	3.13e-134	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOKFKOHM_01165	3.38e-14	yqgO	-	-	-	-	-	-	-
IOKFKOHM_01166	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
IOKFKOHM_01167	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
IOKFKOHM_01168	2.31e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IOKFKOHM_01169	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IOKFKOHM_01170	1.19e-280	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
IOKFKOHM_01171	7.7e-256	yqgU	-	-	-	-	-	-	-
IOKFKOHM_01172	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
IOKFKOHM_01173	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
IOKFKOHM_01174	7.54e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
IOKFKOHM_01175	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
IOKFKOHM_01176	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
IOKFKOHM_01178	8.33e-191	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOKFKOHM_01179	4.74e-304	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOKFKOHM_01180	2.92e-231	yqxL	-	-	P	-	-	-	Mg2 transporter protein
IOKFKOHM_01181	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IOKFKOHM_01182	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IOKFKOHM_01183	8.73e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
IOKFKOHM_01184	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
IOKFKOHM_01185	1.13e-92	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
IOKFKOHM_01186	7.23e-78	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
IOKFKOHM_01187	4.1e-60	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IOKFKOHM_01188	3.78e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
IOKFKOHM_01189	3.33e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
IOKFKOHM_01190	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IOKFKOHM_01191	9.33e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
IOKFKOHM_01192	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
IOKFKOHM_01193	9e-182	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
IOKFKOHM_01194	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
IOKFKOHM_01195	1.39e-33	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
IOKFKOHM_01196	2.52e-194	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
IOKFKOHM_01197	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IOKFKOHM_01198	3.31e-262	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
IOKFKOHM_01199	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IOKFKOHM_01200	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IOKFKOHM_01201	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
IOKFKOHM_01202	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IOKFKOHM_01203	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IOKFKOHM_01204	4.05e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IOKFKOHM_01205	5.18e-81	yqhP	-	-	-	-	-	-	-
IOKFKOHM_01206	1.42e-218	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
IOKFKOHM_01207	6.59e-120	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
IOKFKOHM_01208	1.12e-99	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
IOKFKOHM_01209	6.04e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IOKFKOHM_01210	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOKFKOHM_01211	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
IOKFKOHM_01212	5.79e-217	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
IOKFKOHM_01213	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
IOKFKOHM_01214	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
IOKFKOHM_01215	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
IOKFKOHM_01216	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
IOKFKOHM_01217	2.58e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
IOKFKOHM_01218	5.35e-149	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
IOKFKOHM_01219	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
IOKFKOHM_01220	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOKFKOHM_01221	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IOKFKOHM_01222	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_01223	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOKFKOHM_01224	1.24e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOKFKOHM_01225	1.02e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOKFKOHM_01226	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOKFKOHM_01227	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOKFKOHM_01228	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOKFKOHM_01229	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
IOKFKOHM_01230	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOKFKOHM_01231	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IOKFKOHM_01232	3.6e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
IOKFKOHM_01233	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IOKFKOHM_01234	6.63e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IOKFKOHM_01235	4.74e-37	-	-	-	-	-	-	-	-
IOKFKOHM_01236	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
IOKFKOHM_01237	9.7e-168	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IOKFKOHM_01238	3.16e-278	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IOKFKOHM_01239	3.99e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
IOKFKOHM_01240	2.45e-268	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
IOKFKOHM_01241	1.85e-264	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IOKFKOHM_01242	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
IOKFKOHM_01243	7.23e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IOKFKOHM_01244	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
IOKFKOHM_01245	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
IOKFKOHM_01246	8.64e-199	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
IOKFKOHM_01247	2.24e-261	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOKFKOHM_01248	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
IOKFKOHM_01249	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOKFKOHM_01250	1.58e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOKFKOHM_01251	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOKFKOHM_01252	4.21e-285	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOKFKOHM_01253	2.03e-190	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
IOKFKOHM_01254	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_01255	1.65e-211	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IOKFKOHM_01256	6.29e-100	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
IOKFKOHM_01257	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOKFKOHM_01258	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IOKFKOHM_01259	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IOKFKOHM_01260	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
IOKFKOHM_01261	9.84e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_01263	5.45e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
IOKFKOHM_01264	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOKFKOHM_01265	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
IOKFKOHM_01266	1.99e-180	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
IOKFKOHM_01267	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOKFKOHM_01268	1.77e-32	yqzJ	-	-	-	-	-	-	-
IOKFKOHM_01269	1.84e-299	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOKFKOHM_01270	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOKFKOHM_01271	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOKFKOHM_01272	2.2e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOKFKOHM_01273	8.35e-20	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IOKFKOHM_01274	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOKFKOHM_01275	1.72e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IOKFKOHM_01276	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IOKFKOHM_01277	5.62e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOKFKOHM_01278	5.2e-226	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IOKFKOHM_01279	1.39e-184	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_01280	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
IOKFKOHM_01281	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IOKFKOHM_01282	1.33e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOKFKOHM_01284	2.87e-249	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
IOKFKOHM_01286	1.46e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOKFKOHM_01287	3.23e-66	yqiX	-	-	S	-	-	-	YolD-like protein
IOKFKOHM_01288	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IOKFKOHM_01289	6.7e-73	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
IOKFKOHM_01290	6.52e-248	yqkA	-	-	K	-	-	-	GrpB protein
IOKFKOHM_01291	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
IOKFKOHM_01292	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
IOKFKOHM_01293	5.8e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IOKFKOHM_01294	6.61e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
IOKFKOHM_01295	1.04e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
IOKFKOHM_01296	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
IOKFKOHM_01297	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
IOKFKOHM_01298	9.79e-279	yqxK	-	-	L	-	-	-	DNA helicase
IOKFKOHM_01299	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_01300	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
IOKFKOHM_01301	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
IOKFKOHM_01302	1.14e-309	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IOKFKOHM_01303	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IOKFKOHM_01304	7.27e-42	yqkK	-	-	-	-	-	-	-
IOKFKOHM_01305	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IOKFKOHM_01306	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IOKFKOHM_01307	5.51e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
IOKFKOHM_01308	3.75e-212	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
IOKFKOHM_01309	4.59e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOKFKOHM_01310	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IOKFKOHM_01311	5.58e-270	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IOKFKOHM_01312	3e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
IOKFKOHM_01313	1.37e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IOKFKOHM_01314	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOKFKOHM_01315	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
IOKFKOHM_01316	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
IOKFKOHM_01317	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
IOKFKOHM_01318	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
IOKFKOHM_01319	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IOKFKOHM_01320	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IOKFKOHM_01321	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
IOKFKOHM_01322	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOKFKOHM_01323	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
IOKFKOHM_01324	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOKFKOHM_01330	4.28e-42	-	-	-	S	-	-	-	Pfam Transposase IS66
IOKFKOHM_01331	1.5e-33	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOKFKOHM_01333	1.75e-43	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
IOKFKOHM_01334	1.67e-125	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOKFKOHM_01335	5.98e-72	ypuD	-	-	-	-	-	-	-
IOKFKOHM_01336	1.39e-258	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IOKFKOHM_01337	1.24e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IOKFKOHM_01338	1.04e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IOKFKOHM_01339	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IOKFKOHM_01340	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOKFKOHM_01341	1.4e-117	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
IOKFKOHM_01342	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOKFKOHM_01343	9.54e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOKFKOHM_01344	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
IOKFKOHM_01345	1.18e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IOKFKOHM_01346	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
IOKFKOHM_01347	1.43e-112	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
IOKFKOHM_01348	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOKFKOHM_01349	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IOKFKOHM_01350	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
IOKFKOHM_01351	1.56e-277	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IOKFKOHM_01352	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_01353	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_01354	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_01355	6.08e-254	rsiX	-	-	-	-	-	-	-
IOKFKOHM_01356	4.59e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IOKFKOHM_01357	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOKFKOHM_01358	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOKFKOHM_01359	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
IOKFKOHM_01360	1.28e-254	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
IOKFKOHM_01361	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOKFKOHM_01362	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
IOKFKOHM_01363	3.5e-142	ypbE	-	-	M	-	-	-	Lysin motif
IOKFKOHM_01364	1.66e-105	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
IOKFKOHM_01365	5.05e-187	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IOKFKOHM_01366	3.22e-135	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IOKFKOHM_01367	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOKFKOHM_01368	2.51e-222	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
IOKFKOHM_01369	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
IOKFKOHM_01370	1.99e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
IOKFKOHM_01371	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
IOKFKOHM_01372	2.57e-141	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
IOKFKOHM_01373	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
IOKFKOHM_01374	2.36e-145	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IOKFKOHM_01375	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IOKFKOHM_01376	5.43e-234	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOKFKOHM_01377	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
IOKFKOHM_01378	1.11e-133	yphA	-	-	-	-	-	-	-
IOKFKOHM_01379	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
IOKFKOHM_01380	2.06e-38	ypzH	-	-	-	-	-	-	-
IOKFKOHM_01381	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IOKFKOHM_01382	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IOKFKOHM_01383	1.43e-26	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
IOKFKOHM_01384	8.71e-176	yphF	-	-	-	-	-	-	-
IOKFKOHM_01385	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IOKFKOHM_01386	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOKFKOHM_01387	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IOKFKOHM_01388	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IOKFKOHM_01389	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IOKFKOHM_01390	5.46e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IOKFKOHM_01391	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOKFKOHM_01392	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IOKFKOHM_01393	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
IOKFKOHM_01394	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOKFKOHM_01395	5.72e-263	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOKFKOHM_01396	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IOKFKOHM_01397	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOKFKOHM_01398	5e-229	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOKFKOHM_01399	4.18e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IOKFKOHM_01400	8.71e-148	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
IOKFKOHM_01401	1.81e-292	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOKFKOHM_01402	3.14e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOKFKOHM_01403	2.6e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOKFKOHM_01404	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IOKFKOHM_01405	9.49e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOKFKOHM_01406	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
IOKFKOHM_01407	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
IOKFKOHM_01408	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
IOKFKOHM_01409	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
IOKFKOHM_01410	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
IOKFKOHM_01411	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
IOKFKOHM_01412	1.15e-125	ypjA	-	-	S	-	-	-	membrane
IOKFKOHM_01413	6.56e-181	ypjB	-	-	S	-	-	-	sporulation protein
IOKFKOHM_01414	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOKFKOHM_01415	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
IOKFKOHM_01416	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOKFKOHM_01417	1.03e-92	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
IOKFKOHM_01418	2.69e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
IOKFKOHM_01419	4.94e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
IOKFKOHM_01420	1.06e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOKFKOHM_01421	6.91e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOKFKOHM_01422	9.79e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IOKFKOHM_01423	1.57e-199	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IOKFKOHM_01424	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IOKFKOHM_01425	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IOKFKOHM_01426	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
IOKFKOHM_01427	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_01428	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IOKFKOHM_01429	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
IOKFKOHM_01430	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
IOKFKOHM_01431	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOKFKOHM_01432	1.43e-121	ypoC	-	-	-	-	-	-	-
IOKFKOHM_01433	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IOKFKOHM_01434	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOKFKOHM_01435	4.54e-241	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
IOKFKOHM_01438	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
IOKFKOHM_01439	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
IOKFKOHM_01440	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
IOKFKOHM_01441	1.76e-94	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IOKFKOHM_01442	6.45e-111	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
IOKFKOHM_01443	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IOKFKOHM_01444	7.21e-301	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
IOKFKOHM_01445	3.41e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IOKFKOHM_01446	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOKFKOHM_01447	1.16e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IOKFKOHM_01449	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
IOKFKOHM_01450	4.44e-174	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_01451	1.2e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IOKFKOHM_01452	1.19e-234	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
IOKFKOHM_01453	6.95e-238	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
IOKFKOHM_01454	1.03e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
IOKFKOHM_01455	3.35e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IOKFKOHM_01456	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IOKFKOHM_01457	5.51e-127	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOKFKOHM_01458	4.98e-291	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IOKFKOHM_01459	4.36e-264	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
IOKFKOHM_01460	9.54e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
IOKFKOHM_01461	0.0	ypbR	-	-	S	-	-	-	Dynamin family
IOKFKOHM_01462	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
IOKFKOHM_01463	1.08e-11	-	-	-	-	-	-	-	-
IOKFKOHM_01464	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
IOKFKOHM_01465	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
IOKFKOHM_01466	7.64e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
IOKFKOHM_01467	3.27e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IOKFKOHM_01468	6.45e-173	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
IOKFKOHM_01469	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
IOKFKOHM_01470	5.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
IOKFKOHM_01471	1.17e-22	degR	-	-	-	-	-	-	-
IOKFKOHM_01472	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IOKFKOHM_01473	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IOKFKOHM_01474	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IOKFKOHM_01475	3.13e-114	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IOKFKOHM_01476	8.09e-139	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IOKFKOHM_01477	9.9e-205	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
IOKFKOHM_01478	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IOKFKOHM_01479	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
IOKFKOHM_01480	1.45e-185	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
IOKFKOHM_01481	1.16e-146	ypjP	-	-	S	-	-	-	YpjP-like protein
IOKFKOHM_01482	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IOKFKOHM_01483	2.45e-124	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOKFKOHM_01484	1.71e-145	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IOKFKOHM_01485	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
IOKFKOHM_01486	1.4e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_01487	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IOKFKOHM_01488	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
IOKFKOHM_01489	2.77e-140	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IOKFKOHM_01490	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOKFKOHM_01491	1.95e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_01492	8.69e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
IOKFKOHM_01493	7.03e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
IOKFKOHM_01494	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
IOKFKOHM_01495	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOKFKOHM_01496	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IOKFKOHM_01497	5.51e-156	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IOKFKOHM_01498	3.83e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
IOKFKOHM_01499	6.33e-226	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
IOKFKOHM_01500	1.79e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
IOKFKOHM_01501	1.06e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
IOKFKOHM_01502	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
IOKFKOHM_01503	3.27e-183	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
IOKFKOHM_01505	3.28e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOKFKOHM_01506	1.39e-160	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IOKFKOHM_01507	2.71e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IOKFKOHM_01508	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
IOKFKOHM_01509	1.84e-197	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
IOKFKOHM_01510	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
IOKFKOHM_01511	1.4e-62	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
IOKFKOHM_01512	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IOKFKOHM_01513	1.29e-159	yodN	-	-	-	-	-	-	-
IOKFKOHM_01515	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
IOKFKOHM_01516	4.02e-138	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IOKFKOHM_01517	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
IOKFKOHM_01518	2.08e-12	-	-	-	-	-	-	-	-
IOKFKOHM_01519	6.86e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IOKFKOHM_01520	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IOKFKOHM_01521	4.86e-41	yodI	-	-	-	-	-	-	-
IOKFKOHM_01522	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
IOKFKOHM_01523	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IOKFKOHM_01524	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOKFKOHM_01525	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IOKFKOHM_01526	1.88e-220	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IOKFKOHM_01527	3.61e-144	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
IOKFKOHM_01528	6.44e-139	yodC	-	-	C	-	-	-	nitroreductase
IOKFKOHM_01529	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
IOKFKOHM_01530	3.97e-84	iolK	-	-	S	-	-	-	tautomerase
IOKFKOHM_01531	7.01e-96	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IOKFKOHM_01532	1.26e-168	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IOKFKOHM_01533	5.59e-14	-	-	-	-	-	-	-	-
IOKFKOHM_01534	7.43e-107	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
IOKFKOHM_01535	1.64e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
IOKFKOHM_01536	1.85e-58	-	-	-	-	-	-	-	-
IOKFKOHM_01537	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
IOKFKOHM_01538	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
IOKFKOHM_01539	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOKFKOHM_01540	5.06e-314	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
IOKFKOHM_01542	3.69e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOKFKOHM_01543	3.79e-292	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
IOKFKOHM_01544	1.07e-266	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IOKFKOHM_01545	3.62e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IOKFKOHM_01546	8.98e-206	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
IOKFKOHM_01547	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
IOKFKOHM_01548	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IOKFKOHM_01549	3.02e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IOKFKOHM_01550	5.48e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
IOKFKOHM_01551	2.93e-298	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IOKFKOHM_01552	1.3e-206	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
IOKFKOHM_01553	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
IOKFKOHM_01554	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOKFKOHM_01555	1.91e-42	yozC	-	-	-	-	-	-	-
IOKFKOHM_01556	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
IOKFKOHM_01557	1.83e-49	yocN	-	-	-	-	-	-	-
IOKFKOHM_01558	2.94e-55	yozN	-	-	-	-	-	-	-
IOKFKOHM_01559	5.43e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IOKFKOHM_01560	3.79e-39	-	-	-	-	-	-	-	-
IOKFKOHM_01561	4.29e-70	yocL	-	-	-	-	-	-	-
IOKFKOHM_01562	2.87e-107	yocK	-	-	T	-	-	-	general stress protein
IOKFKOHM_01563	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOKFKOHM_01564	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOKFKOHM_01565	1.17e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
IOKFKOHM_01567	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOKFKOHM_01568	4.99e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_01569	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
IOKFKOHM_01570	4.72e-241	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
IOKFKOHM_01571	1.8e-120	yocC	-	-	-	-	-	-	-
IOKFKOHM_01572	4.31e-184	-	-	-	-	-	-	-	-
IOKFKOHM_01573	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
IOKFKOHM_01574	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IOKFKOHM_01575	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
IOKFKOHM_01576	1.37e-116	yobW	-	-	-	-	-	-	-
IOKFKOHM_01577	2.76e-220	yobV	-	-	K	-	-	-	WYL domain
IOKFKOHM_01578	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IOKFKOHM_01579	4.49e-168	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IOKFKOHM_01580	7.27e-126	yobS	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_01581	1.98e-178	-	-	-	J	-	-	-	FR47-like protein
IOKFKOHM_01582	2.64e-159	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOKFKOHM_01583	9e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
IOKFKOHM_01584	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
IOKFKOHM_01585	3.14e-129	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
IOKFKOHM_01586	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOKFKOHM_01587	6.69e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
IOKFKOHM_01588	1.7e-96	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
IOKFKOHM_01589	1.41e-128	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
IOKFKOHM_01590	4.52e-40	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOKFKOHM_01591	5.78e-44	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOKFKOHM_01594	1.29e-61	-	-	-	S	-	-	-	YolD-like protein
IOKFKOHM_01595	4.62e-211	-	-	-	S	-	-	-	damaged DNA binding
IOKFKOHM_01597	2.14e-17	-	-	-	Q	-	-	-	methyltransferase
IOKFKOHM_01598	4.01e-33	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
IOKFKOHM_01599	0.000751	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IOKFKOHM_01600	3.91e-52	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOKFKOHM_01602	4.47e-121	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IOKFKOHM_01604	9.95e-23	-	-	-	-	-	-	-	-
IOKFKOHM_01605	3.23e-86	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
IOKFKOHM_01606	3.12e-98	-	-	-	-	-	-	-	-
IOKFKOHM_01608	3.46e-10	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IOKFKOHM_01609	4.98e-106	yoaW	-	-	-	-	-	-	-
IOKFKOHM_01610	2.82e-36	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IOKFKOHM_01611	6.23e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IOKFKOHM_01612	3.25e-67	ynaF	-	-	-	-	-	-	-
IOKFKOHM_01619	1.15e-22	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IOKFKOHM_01620	3.98e-168	-	-	-	-	-	-	-	-
IOKFKOHM_01621	2.49e-43	yoaF	-	-	-	-	-	-	-
IOKFKOHM_01623	2.11e-49	-	-	-	S	-	-	-	TM2 domain
IOKFKOHM_01625	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
IOKFKOHM_01626	8.64e-171	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
IOKFKOHM_01627	8.63e-297	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
IOKFKOHM_01630	2.97e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
IOKFKOHM_01631	4.18e-148	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
IOKFKOHM_01632	1.89e-100	yoaW	-	-	-	-	-	-	-
IOKFKOHM_01633	3.7e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
IOKFKOHM_01634	1.35e-202	yoaU	-	-	K	-	-	-	LysR substrate binding domain
IOKFKOHM_01635	5.46e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
IOKFKOHM_01636	4.17e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_01637	2.65e-97	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
IOKFKOHM_01638	1.48e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
IOKFKOHM_01639	3.47e-109	-	-	-	-	-	-	-	-
IOKFKOHM_01642	1.45e-118	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IOKFKOHM_01644	1.99e-168	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
IOKFKOHM_01645	1.43e-252	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
IOKFKOHM_01646	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
IOKFKOHM_01647	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
IOKFKOHM_01648	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
IOKFKOHM_01649	1.29e-281	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
IOKFKOHM_01650	2.99e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
IOKFKOHM_01651	1.46e-19	-	-	-	-	-	-	-	-
IOKFKOHM_01652	1.17e-12	-	-	-	-	-	-	-	-
IOKFKOHM_01653	3.99e-114	degA	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_01654	5.3e-193	-	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
IOKFKOHM_01655	3.41e-259	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
IOKFKOHM_01656	2.73e-214	-	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOKFKOHM_01657	3.48e-43	yoaF	-	-	-	-	-	-	-
IOKFKOHM_01658	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOKFKOHM_01659	3.36e-234	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOKFKOHM_01660	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IOKFKOHM_01661	6.14e-298	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
IOKFKOHM_01662	6.7e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_01663	7.41e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOKFKOHM_01664	1.25e-121	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOKFKOHM_01665	1.39e-164	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOKFKOHM_01666	2.81e-123	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOKFKOHM_01667	1.73e-172	yoxB	-	-	-	-	-	-	-
IOKFKOHM_01668	1.1e-50	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
IOKFKOHM_01669	2.28e-159	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_01670	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IOKFKOHM_01671	4.51e-184	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOKFKOHM_01672	4.51e-260	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOKFKOHM_01673	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_01674	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
IOKFKOHM_01675	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IOKFKOHM_01676	1.7e-236	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IOKFKOHM_01677	1.3e-202	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_01678	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IOKFKOHM_01679	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
IOKFKOHM_01680	1.14e-124	-	-	-	L	-	-	-	Integrase
IOKFKOHM_01682	8.34e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
IOKFKOHM_01683	1.14e-311	yoeA	-	-	V	-	-	-	MATE efflux family protein
IOKFKOHM_01684	1.92e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOKFKOHM_01685	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IOKFKOHM_01686	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOKFKOHM_01687	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
IOKFKOHM_01688	2.48e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IOKFKOHM_01689	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
IOKFKOHM_01690	1.53e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IOKFKOHM_01691	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IOKFKOHM_01692	2.81e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
IOKFKOHM_01693	7.15e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
IOKFKOHM_01694	5.53e-211	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
IOKFKOHM_01695	7.04e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
IOKFKOHM_01696	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOKFKOHM_01697	3.01e-295	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
IOKFKOHM_01698	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
IOKFKOHM_01699	2.74e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOKFKOHM_01700	1.72e-103	yngA	-	-	S	-	-	-	membrane
IOKFKOHM_01701	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOKFKOHM_01702	2.36e-315	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
IOKFKOHM_01704	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
IOKFKOHM_01705	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IOKFKOHM_01706	8.74e-75	ynfC	-	-	-	-	-	-	-
IOKFKOHM_01707	1.82e-18	-	-	-	-	-	-	-	-
IOKFKOHM_01708	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOKFKOHM_01709	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOKFKOHM_01710	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
IOKFKOHM_01711	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOKFKOHM_01712	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IOKFKOHM_01713	3.3e-71	yneQ	-	-	-	-	-	-	-
IOKFKOHM_01714	1.15e-94	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IOKFKOHM_01715	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
IOKFKOHM_01717	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
IOKFKOHM_01718	2.53e-118	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IOKFKOHM_01719	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IOKFKOHM_01720	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
IOKFKOHM_01721	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
IOKFKOHM_01722	7.02e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
IOKFKOHM_01723	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
IOKFKOHM_01724	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
IOKFKOHM_01725	2.12e-77	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
IOKFKOHM_01726	5.63e-163	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
IOKFKOHM_01727	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IOKFKOHM_01728	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IOKFKOHM_01729	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
IOKFKOHM_01730	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IOKFKOHM_01731	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
IOKFKOHM_01732	2.29e-144	yneB	-	-	L	-	-	-	resolvase
IOKFKOHM_01733	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IOKFKOHM_01734	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOKFKOHM_01735	3.01e-102	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IOKFKOHM_01736	1.32e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IOKFKOHM_01737	2.68e-174	yndL	-	-	S	-	-	-	Replication protein
IOKFKOHM_01740	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
IOKFKOHM_01741	9.53e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
IOKFKOHM_01742	2.52e-196	yndG	-	-	S	-	-	-	DoxX-like family
IOKFKOHM_01743	6.77e-108	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IOKFKOHM_01744	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IOKFKOHM_01747	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
IOKFKOHM_01748	8.92e-96	-	-	-	-	-	-	-	-
IOKFKOHM_01749	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
IOKFKOHM_01752	2.43e-162	-	-	-	S	-	-	-	Domain of unknown function, YrpD
IOKFKOHM_01754	7.89e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOKFKOHM_01757	7.54e-22	-	-	-	-	-	-	-	-
IOKFKOHM_01758	1.22e-101	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
IOKFKOHM_01760	4.34e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOKFKOHM_01761	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOKFKOHM_01762	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
IOKFKOHM_01763	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
IOKFKOHM_01764	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IOKFKOHM_01765	5.85e-274	xylR	-	-	GK	-	-	-	ROK family
IOKFKOHM_01766	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOKFKOHM_01767	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IOKFKOHM_01768	2.81e-106	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
IOKFKOHM_01770	7.31e-21	ynaF	-	-	-	-	-	-	-
IOKFKOHM_01771	3.27e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IOKFKOHM_01772	8.64e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IOKFKOHM_01773	2.38e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IOKFKOHM_01774	3.24e-93	-	-	-	S	-	-	-	CAAX protease self-immunity
IOKFKOHM_01776	8.3e-126	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOKFKOHM_01777	2.61e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IOKFKOHM_01778	6.64e-145	ynaC	-	-	-	-	-	-	-
IOKFKOHM_01779	2.05e-116	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
IOKFKOHM_01780	2.22e-23	-	-	-	-	-	-	-	-
IOKFKOHM_01781	2.03e-39	-	-	-	-	-	-	-	-
IOKFKOHM_01782	8.68e-14	-	-	-	-	-	-	-	-
IOKFKOHM_01783	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOKFKOHM_01784	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
IOKFKOHM_01785	1.95e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IOKFKOHM_01786	1.05e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOKFKOHM_01787	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
IOKFKOHM_01788	1.16e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IOKFKOHM_01789	2.24e-141	-	-	-	-	-	-	-	-
IOKFKOHM_01790	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOKFKOHM_01791	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOKFKOHM_01792	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IOKFKOHM_01793	1.2e-30	ymzA	-	-	-	-	-	-	-
IOKFKOHM_01794	1.63e-31	-	-	-	-	-	-	-	-
IOKFKOHM_01795	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IOKFKOHM_01796	1.38e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOKFKOHM_01797	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
IOKFKOHM_01799	2.02e-66	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IOKFKOHM_01800	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
IOKFKOHM_01801	5.98e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
IOKFKOHM_01802	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
IOKFKOHM_01804	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
IOKFKOHM_01805	1.88e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IOKFKOHM_01806	5.65e-81	ymzB	-	-	-	-	-	-	-
IOKFKOHM_01807	1.02e-134	pksA	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_01808	9.3e-126	ymcC	-	-	S	-	-	-	Membrane
IOKFKOHM_01809	6.68e-92	-	-	-	S	-	-	-	Regulatory protein YrvL
IOKFKOHM_01811	6.74e-88	-	-	-	S	-	-	-	Phage terminase, small subunit
IOKFKOHM_01812	8.79e-12	-	-	-	-	-	-	-	-
IOKFKOHM_01813	1.9e-77	-	-	-	S	-	-	-	HNH endonuclease
IOKFKOHM_01814	0.000711	-	-	-	-	-	-	-	-
IOKFKOHM_01817	1.61e-74	-	-	-	L	-	-	-	Phage integrase family
IOKFKOHM_01818	5.52e-31	-	-	-	M	-	-	-	ArpU family transcriptional regulator
IOKFKOHM_01823	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOKFKOHM_01824	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOKFKOHM_01825	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
IOKFKOHM_01826	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
IOKFKOHM_01827	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IOKFKOHM_01828	2.4e-277	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOKFKOHM_01829	1.38e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IOKFKOHM_01830	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
IOKFKOHM_01831	3.57e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
IOKFKOHM_01832	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IOKFKOHM_01833	1.82e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
IOKFKOHM_01834	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOKFKOHM_01835	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IOKFKOHM_01836	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOKFKOHM_01837	3.56e-176	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
IOKFKOHM_01838	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
IOKFKOHM_01839	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IOKFKOHM_01840	3.01e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IOKFKOHM_01841	1.37e-308	ymfH	-	-	S	-	-	-	zinc protease
IOKFKOHM_01842	3.86e-298	albE	-	-	S	-	-	-	Peptidase M16
IOKFKOHM_01843	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_01844	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_01845	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOKFKOHM_01846	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
IOKFKOHM_01847	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
IOKFKOHM_01848	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOKFKOHM_01849	3.7e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOKFKOHM_01850	2.83e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOKFKOHM_01851	9.62e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOKFKOHM_01852	8.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IOKFKOHM_01853	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
IOKFKOHM_01854	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
IOKFKOHM_01855	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
IOKFKOHM_01856	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
IOKFKOHM_01857	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IOKFKOHM_01858	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOKFKOHM_01859	9.42e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IOKFKOHM_01860	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOKFKOHM_01861	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOKFKOHM_01862	6.45e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
IOKFKOHM_01863	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOKFKOHM_01864	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
IOKFKOHM_01865	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
IOKFKOHM_01866	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IOKFKOHM_01867	1.56e-103	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IOKFKOHM_01868	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOKFKOHM_01869	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOKFKOHM_01870	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IOKFKOHM_01871	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IOKFKOHM_01872	1.65e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IOKFKOHM_01873	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOKFKOHM_01874	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOKFKOHM_01875	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IOKFKOHM_01876	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOKFKOHM_01877	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IOKFKOHM_01878	1.34e-98	ylxL	-	-	-	-	-	-	-
IOKFKOHM_01879	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOKFKOHM_01880	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IOKFKOHM_01881	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IOKFKOHM_01882	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
IOKFKOHM_01883	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
IOKFKOHM_01884	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IOKFKOHM_01885	3.14e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
IOKFKOHM_01886	8.03e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
IOKFKOHM_01887	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IOKFKOHM_01888	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IOKFKOHM_01889	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
IOKFKOHM_01890	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
IOKFKOHM_01891	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
IOKFKOHM_01892	1.3e-135	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
IOKFKOHM_01893	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
IOKFKOHM_01894	4.7e-245	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IOKFKOHM_01895	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IOKFKOHM_01896	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
IOKFKOHM_01897	1.42e-175	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
IOKFKOHM_01898	5.67e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
IOKFKOHM_01899	1.36e-306	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
IOKFKOHM_01900	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
IOKFKOHM_01901	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
IOKFKOHM_01902	3.5e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IOKFKOHM_01903	4.51e-143	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
IOKFKOHM_01904	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IOKFKOHM_01905	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
IOKFKOHM_01906	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
IOKFKOHM_01907	2.16e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
IOKFKOHM_01908	9.37e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IOKFKOHM_01909	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IOKFKOHM_01910	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOKFKOHM_01911	1.74e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOKFKOHM_01912	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
IOKFKOHM_01913	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOKFKOHM_01914	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOKFKOHM_01915	2.66e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
IOKFKOHM_01916	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IOKFKOHM_01917	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IOKFKOHM_01918	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
IOKFKOHM_01919	0.0	ylqG	-	-	-	-	-	-	-
IOKFKOHM_01920	2.89e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOKFKOHM_01921	4.89e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOKFKOHM_01922	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOKFKOHM_01923	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IOKFKOHM_01924	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOKFKOHM_01925	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
IOKFKOHM_01926	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IOKFKOHM_01927	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IOKFKOHM_01928	1.96e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOKFKOHM_01929	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOKFKOHM_01930	1.67e-114	-	-	-	-	-	-	-	-
IOKFKOHM_01931	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOKFKOHM_01932	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IOKFKOHM_01933	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOKFKOHM_01934	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOKFKOHM_01935	5.81e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IOKFKOHM_01936	1.53e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IOKFKOHM_01937	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOKFKOHM_01938	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IOKFKOHM_01939	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOKFKOHM_01940	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IOKFKOHM_01941	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IOKFKOHM_01942	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
IOKFKOHM_01943	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_01944	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IOKFKOHM_01945	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IOKFKOHM_01946	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IOKFKOHM_01947	4.57e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOKFKOHM_01948	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IOKFKOHM_01949	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IOKFKOHM_01950	5.3e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IOKFKOHM_01951	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOKFKOHM_01952	2.21e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOKFKOHM_01953	2.38e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOKFKOHM_01954	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOKFKOHM_01955	5.13e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOKFKOHM_01956	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOKFKOHM_01957	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOKFKOHM_01958	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
IOKFKOHM_01959	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
IOKFKOHM_01960	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
IOKFKOHM_01961	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IOKFKOHM_01962	9.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
IOKFKOHM_01963	1.45e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
IOKFKOHM_01964	5.9e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IOKFKOHM_01965	3.76e-140	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IOKFKOHM_01966	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IOKFKOHM_01967	6.01e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
IOKFKOHM_01968	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IOKFKOHM_01970	1.27e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOKFKOHM_01971	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOKFKOHM_01972	1.22e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOKFKOHM_01973	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IOKFKOHM_01974	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
IOKFKOHM_01975	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IOKFKOHM_01976	9.71e-317	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOKFKOHM_01977	7.29e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IOKFKOHM_01978	3.71e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
IOKFKOHM_01979	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOKFKOHM_01980	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOKFKOHM_01981	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOKFKOHM_01982	9.18e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IOKFKOHM_01983	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOKFKOHM_01984	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
IOKFKOHM_01985	4.28e-178	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
IOKFKOHM_01986	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
IOKFKOHM_01987	1.28e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOKFKOHM_01988	1.05e-160	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOKFKOHM_01989	3.73e-203	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
IOKFKOHM_01990	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
IOKFKOHM_01991	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
IOKFKOHM_01992	4.49e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IOKFKOHM_01993	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOKFKOHM_01994	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOKFKOHM_01995	4.25e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IOKFKOHM_01997	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
IOKFKOHM_01998	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOKFKOHM_01999	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOKFKOHM_02000	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
IOKFKOHM_02001	8.67e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02002	3.45e-146	ylxW	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02003	1.37e-177	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOKFKOHM_02004	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
IOKFKOHM_02005	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOKFKOHM_02006	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOKFKOHM_02007	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOKFKOHM_02008	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOKFKOHM_02009	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOKFKOHM_02010	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
IOKFKOHM_02011	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IOKFKOHM_02012	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
IOKFKOHM_02013	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOKFKOHM_02014	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IOKFKOHM_02015	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IOKFKOHM_02016	9.23e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOKFKOHM_02017	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
IOKFKOHM_02018	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IOKFKOHM_02019	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IOKFKOHM_02020	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
IOKFKOHM_02022	8.29e-292	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IOKFKOHM_02023	2.24e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IOKFKOHM_02024	1.04e-175	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IOKFKOHM_02025	9.11e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
IOKFKOHM_02026	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOKFKOHM_02027	1.74e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
IOKFKOHM_02028	8.8e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
IOKFKOHM_02029	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
IOKFKOHM_02030	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
IOKFKOHM_02031	3.78e-88	ylbD	-	-	S	-	-	-	Putative coat protein
IOKFKOHM_02032	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
IOKFKOHM_02033	1.53e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
IOKFKOHM_02034	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
IOKFKOHM_02035	1.21e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
IOKFKOHM_02036	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IOKFKOHM_02037	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IOKFKOHM_02038	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IOKFKOHM_02039	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IOKFKOHM_02040	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IOKFKOHM_02041	2e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IOKFKOHM_02042	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IOKFKOHM_02043	7.05e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOKFKOHM_02044	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
IOKFKOHM_02045	1e-218	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IOKFKOHM_02046	1.09e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IOKFKOHM_02047	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
IOKFKOHM_02048	1.64e-124	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOKFKOHM_02049	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02050	8.88e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
IOKFKOHM_02051	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IOKFKOHM_02052	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
IOKFKOHM_02053	1.74e-57	ylaE	-	-	-	-	-	-	-
IOKFKOHM_02055	4.16e-114	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_02056	1.18e-55	ylaB	-	-	-	-	-	-	-
IOKFKOHM_02057	0.0	ylaA	-	-	-	-	-	-	-
IOKFKOHM_02058	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IOKFKOHM_02059	3.19e-79	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02060	3.63e-168	-	-	-	I	-	-	-	Carboxylesterase family
IOKFKOHM_02061	2.88e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IOKFKOHM_02062	2.98e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
IOKFKOHM_02063	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
IOKFKOHM_02064	4.48e-35	ykzI	-	-	-	-	-	-	-
IOKFKOHM_02065	1.45e-149	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IOKFKOHM_02066	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IOKFKOHM_02067	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
IOKFKOHM_02068	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
IOKFKOHM_02069	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOKFKOHM_02070	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOKFKOHM_02071	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOKFKOHM_02072	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOKFKOHM_02073	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
IOKFKOHM_02074	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IOKFKOHM_02075	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOKFKOHM_02076	4.79e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
IOKFKOHM_02077	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IOKFKOHM_02078	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOKFKOHM_02079	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IOKFKOHM_02080	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IOKFKOHM_02081	8.06e-197	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
IOKFKOHM_02082	2.65e-306	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IOKFKOHM_02083	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
IOKFKOHM_02084	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
IOKFKOHM_02085	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
IOKFKOHM_02086	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
IOKFKOHM_02087	2.86e-215	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOKFKOHM_02088	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOKFKOHM_02089	5.43e-52	ykoA	-	-	-	-	-	-	-
IOKFKOHM_02090	1.66e-132	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOKFKOHM_02091	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IOKFKOHM_02092	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
IOKFKOHM_02093	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_02094	1.11e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IOKFKOHM_02095	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_02096	4.71e-233	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOKFKOHM_02097	1.31e-150	yknW	-	-	S	-	-	-	Yip1 domain
IOKFKOHM_02098	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOKFKOHM_02099	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOKFKOHM_02100	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IOKFKOHM_02101	1.56e-108	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
IOKFKOHM_02102	9.48e-120	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
IOKFKOHM_02103	4.11e-311	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
IOKFKOHM_02104	1.08e-244	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IOKFKOHM_02105	5.97e-138	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IOKFKOHM_02106	1.41e-199	yknT	-	-	-	ko:K06437	-	ko00000	-
IOKFKOHM_02107	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
IOKFKOHM_02108	1.47e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
IOKFKOHM_02109	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
IOKFKOHM_02110	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
IOKFKOHM_02111	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
IOKFKOHM_02112	1.27e-272	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOKFKOHM_02113	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOKFKOHM_02114	2.95e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IOKFKOHM_02115	2.12e-223	ykuO	-	-	-	-	-	-	-
IOKFKOHM_02116	3.02e-111	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
IOKFKOHM_02117	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02118	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
IOKFKOHM_02119	1.3e-36	ykzF	-	-	S	-	-	-	Antirepressor AbbA
IOKFKOHM_02120	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
IOKFKOHM_02121	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02122	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
IOKFKOHM_02123	2.6e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_02124	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
IOKFKOHM_02125	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02126	3.62e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_02127	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
IOKFKOHM_02128	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
IOKFKOHM_02129	1.05e-22	-	-	-	-	-	-	-	-
IOKFKOHM_02130	5.1e-284	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOKFKOHM_02131	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_02132	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IOKFKOHM_02133	4.4e-171	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
IOKFKOHM_02134	6.67e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IOKFKOHM_02135	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOKFKOHM_02136	3.59e-161	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOKFKOHM_02137	2.49e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
IOKFKOHM_02138	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_02139	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOKFKOHM_02140	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
IOKFKOHM_02141	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_02142	2.29e-166	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
IOKFKOHM_02144	3.82e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02145	2.62e-262	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IOKFKOHM_02146	3.99e-09	-	-	-	-	-	-	-	-
IOKFKOHM_02147	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IOKFKOHM_02148	1.66e-116	stoA	-	-	CO	-	-	-	thiol-disulfide
IOKFKOHM_02149	3.74e-301	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOKFKOHM_02150	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
IOKFKOHM_02151	2.6e-39	-	-	-	-	-	-	-	-
IOKFKOHM_02152	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02153	1.27e-60	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
IOKFKOHM_02154	1.78e-94	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
IOKFKOHM_02155	1.94e-100	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	reverse transcriptase
IOKFKOHM_02159	9.67e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IOKFKOHM_02160	0.0	-	-	-	I	-	-	-	Pfam Lipase (class 3)
IOKFKOHM_02161	2.12e-60	-	-	-	-	-	-	-	-
IOKFKOHM_02162	2.15e-36	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOKFKOHM_02163	9.35e-173	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOKFKOHM_02164	1.22e-80	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IOKFKOHM_02165	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IOKFKOHM_02166	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IOKFKOHM_02167	4.03e-104	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
IOKFKOHM_02168	6.42e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IOKFKOHM_02169	2.02e-228	ykvI	-	-	S	-	-	-	membrane
IOKFKOHM_02170	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IOKFKOHM_02171	2.01e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IOKFKOHM_02172	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IOKFKOHM_02173	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IOKFKOHM_02174	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IOKFKOHM_02175	5.84e-95	eag	-	-	-	-	-	-	-
IOKFKOHM_02177	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
IOKFKOHM_02178	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IOKFKOHM_02179	1.84e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IOKFKOHM_02180	4.34e-176	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IOKFKOHM_02181	9.72e-295	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IOKFKOHM_02182	4.61e-294	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOKFKOHM_02183	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IOKFKOHM_02184	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IOKFKOHM_02185	1.62e-253	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IOKFKOHM_02187	7.91e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOKFKOHM_02188	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_02189	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
IOKFKOHM_02190	1.77e-28	ykzE	-	-	-	-	-	-	-
IOKFKOHM_02192	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
IOKFKOHM_02193	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IOKFKOHM_02194	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
IOKFKOHM_02195	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
IOKFKOHM_02196	4.03e-199	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
IOKFKOHM_02197	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOKFKOHM_02198	1.88e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IOKFKOHM_02199	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
IOKFKOHM_02200	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
IOKFKOHM_02201	2.66e-197	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
IOKFKOHM_02202	1.78e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IOKFKOHM_02203	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
IOKFKOHM_02204	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOKFKOHM_02205	0.0	ykoS	-	-	-	-	-	-	-
IOKFKOHM_02206	1.03e-196	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IOKFKOHM_02207	2.57e-122	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
IOKFKOHM_02208	6.33e-277	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IOKFKOHM_02209	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IOKFKOHM_02210	3.04e-36	ykoL	-	-	-	-	-	-	-
IOKFKOHM_02211	1.63e-25	-	-	-	-	-	-	-	-
IOKFKOHM_02212	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
IOKFKOHM_02213	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
IOKFKOHM_02215	1.45e-08	-	-	-	-	-	-	-	-
IOKFKOHM_02216	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IOKFKOHM_02217	2.26e-144	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IOKFKOHM_02218	3.13e-309	ykoH	-	-	T	-	-	-	Histidine kinase
IOKFKOHM_02219	3.03e-159	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_02220	2.34e-140	ykoF	-	-	S	-	-	-	YKOF-related Family
IOKFKOHM_02221	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOKFKOHM_02222	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_02223	3.65e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IOKFKOHM_02224	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOKFKOHM_02225	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOKFKOHM_02226	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOKFKOHM_02227	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
IOKFKOHM_02228	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IOKFKOHM_02229	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
IOKFKOHM_02230	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IOKFKOHM_02232	3.38e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOKFKOHM_02233	3.16e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOKFKOHM_02234	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IOKFKOHM_02235	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IOKFKOHM_02236	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IOKFKOHM_02237	3.59e-128	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOKFKOHM_02238	1.57e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
IOKFKOHM_02239	3.25e-166	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOKFKOHM_02240	1.15e-13	-	-	-	-	-	-	-	-
IOKFKOHM_02241	5.35e-289	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IOKFKOHM_02242	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
IOKFKOHM_02243	3.62e-167	ykgA	-	-	E	-	-	-	Amidinotransferase
IOKFKOHM_02244	1.34e-259	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
IOKFKOHM_02245	4.88e-236	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOKFKOHM_02246	4.9e-208	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IOKFKOHM_02247	1.14e-255	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IOKFKOHM_02248	1.66e-225	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
IOKFKOHM_02250	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOKFKOHM_02251	1.64e-237	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOKFKOHM_02252	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOKFKOHM_02253	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOKFKOHM_02254	1.63e-195	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
IOKFKOHM_02255	1.93e-177	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
IOKFKOHM_02256	1.98e-283	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOKFKOHM_02258	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOKFKOHM_02259	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOKFKOHM_02260	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IOKFKOHM_02261	1.81e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IOKFKOHM_02262	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
IOKFKOHM_02263	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
IOKFKOHM_02264	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
IOKFKOHM_02265	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
IOKFKOHM_02266	3.73e-208	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IOKFKOHM_02267	1.15e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
IOKFKOHM_02268	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
IOKFKOHM_02269	9.79e-195	xepA	-	-	-	-	-	-	-
IOKFKOHM_02270	6.35e-31	xkdX	-	-	-	-	-	-	-
IOKFKOHM_02271	2.31e-69	xkdW	-	-	S	-	-	-	XkdW protein
IOKFKOHM_02272	0.0	-	-	-	-	-	-	-	-
IOKFKOHM_02273	4.43e-56	-	-	-	-	-	-	-	-
IOKFKOHM_02274	3.92e-135	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IOKFKOHM_02275	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IOKFKOHM_02276	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IOKFKOHM_02277	1.45e-51	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
IOKFKOHM_02278	1.9e-231	xkdQ	-	-	G	-	-	-	NLP P60 protein
IOKFKOHM_02279	2.1e-152	xkdP	-	-	S	-	-	-	Lysin motif
IOKFKOHM_02280	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
IOKFKOHM_02281	3.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
IOKFKOHM_02282	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
IOKFKOHM_02283	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
IOKFKOHM_02284	2.87e-101	xkdJ	-	-	-	-	-	-	-
IOKFKOHM_02285	7.97e-113	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IOKFKOHM_02286	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
IOKFKOHM_02287	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
IOKFKOHM_02288	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
IOKFKOHM_02289	4.02e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
IOKFKOHM_02290	0.0	yqbA	-	-	S	-	-	-	portal protein
IOKFKOHM_02291	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
IOKFKOHM_02292	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
IOKFKOHM_02293	8.12e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IOKFKOHM_02298	8.72e-152	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
IOKFKOHM_02299	2.52e-201	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
IOKFKOHM_02301	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOKFKOHM_02302	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IOKFKOHM_02303	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
IOKFKOHM_02304	1.11e-138	yjqB	-	-	S	-	-	-	Pfam:DUF867
IOKFKOHM_02305	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
IOKFKOHM_02306	3.09e-217	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IOKFKOHM_02307	1.09e-34	-	-	-	S	-	-	-	YCII-related domain
IOKFKOHM_02309	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IOKFKOHM_02310	6.08e-314	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
IOKFKOHM_02311	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
IOKFKOHM_02312	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOKFKOHM_02313	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IOKFKOHM_02314	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
IOKFKOHM_02315	8.11e-237	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IOKFKOHM_02316	3.09e-286	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
IOKFKOHM_02317	1.83e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_02318	1.08e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IOKFKOHM_02319	5.6e-197	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
IOKFKOHM_02320	1.03e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
IOKFKOHM_02321	2.92e-312	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
IOKFKOHM_02322	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IOKFKOHM_02323	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOKFKOHM_02324	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IOKFKOHM_02325	2.36e-116	yjlB	-	-	S	-	-	-	Cupin domain
IOKFKOHM_02326	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
IOKFKOHM_02327	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOKFKOHM_02328	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
IOKFKOHM_02329	3.54e-188	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IOKFKOHM_02330	1.11e-41	-	-	-	-	-	-	-	-
IOKFKOHM_02331	1.76e-279	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IOKFKOHM_02332	4.06e-287	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOKFKOHM_02334	8.38e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IOKFKOHM_02336	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IOKFKOHM_02337	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IOKFKOHM_02338	4.96e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
IOKFKOHM_02339	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
IOKFKOHM_02340	1.12e-210	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
IOKFKOHM_02341	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
IOKFKOHM_02342	6.11e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
IOKFKOHM_02343	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
IOKFKOHM_02345	2.16e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IOKFKOHM_02346	2.7e-68	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
IOKFKOHM_02347	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
IOKFKOHM_02348	9.69e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOKFKOHM_02350	2.17e-118	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOKFKOHM_02351	9.24e-76	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
IOKFKOHM_02352	8.8e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IOKFKOHM_02353	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_02354	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
IOKFKOHM_02355	2.43e-58	yjcN	-	-	-	-	-	-	-
IOKFKOHM_02356	3.01e-60	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IOKFKOHM_02357	1.08e-60	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IOKFKOHM_02364	8.21e-15	-	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02369	1.15e-104	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
IOKFKOHM_02370	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOKFKOHM_02371	1.28e-135	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IOKFKOHM_02378	2.45e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
IOKFKOHM_02379	8.18e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOKFKOHM_02380	3.71e-96	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOKFKOHM_02381	1.85e-80	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
IOKFKOHM_02382	1.38e-66	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
IOKFKOHM_02383	2.09e-103	-	-	-	-	-	-	-	-
IOKFKOHM_02384	7.6e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
IOKFKOHM_02385	8.62e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOKFKOHM_02386	6.49e-58	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOKFKOHM_02387	5.33e-85	-	-	-	-	-	-	-	-
IOKFKOHM_02388	1.19e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
IOKFKOHM_02390	3.48e-43	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IOKFKOHM_02391	3.95e-23	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOKFKOHM_02392	2.75e-31	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOKFKOHM_02394	7.08e-272	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
IOKFKOHM_02395	1.68e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
IOKFKOHM_02396	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IOKFKOHM_02397	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IOKFKOHM_02398	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
IOKFKOHM_02399	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
IOKFKOHM_02400	7.75e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOKFKOHM_02401	6.31e-51	-	-	-	-	-	-	-	-
IOKFKOHM_02402	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOKFKOHM_02403	5.39e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
IOKFKOHM_02405	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IOKFKOHM_02407	1.51e-18	cotW	-	-	-	ko:K06341	-	ko00000	-
IOKFKOHM_02408	1.03e-62	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
IOKFKOHM_02409	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
IOKFKOHM_02410	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
IOKFKOHM_02411	2.32e-107	yjbX	-	-	S	-	-	-	Spore coat protein
IOKFKOHM_02412	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IOKFKOHM_02413	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOKFKOHM_02414	2.52e-237	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IOKFKOHM_02415	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IOKFKOHM_02416	2.18e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
IOKFKOHM_02417	1.33e-276	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
IOKFKOHM_02418	5.7e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
IOKFKOHM_02419	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOKFKOHM_02420	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOKFKOHM_02421	8.09e-181	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IOKFKOHM_02422	1.49e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IOKFKOHM_02423	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOKFKOHM_02424	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
IOKFKOHM_02425	1.54e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
IOKFKOHM_02426	7.32e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02427	2.94e-128	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IOKFKOHM_02428	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
IOKFKOHM_02429	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IOKFKOHM_02431	2.68e-28	-	-	-	-	-	-	-	-
IOKFKOHM_02432	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IOKFKOHM_02433	1.03e-280	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IOKFKOHM_02434	6.34e-147	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IOKFKOHM_02435	2.37e-142	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
IOKFKOHM_02436	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOKFKOHM_02437	2.65e-133	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOKFKOHM_02438	1.18e-267	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOKFKOHM_02439	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOKFKOHM_02440	1.12e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOKFKOHM_02441	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOKFKOHM_02442	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOKFKOHM_02443	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOKFKOHM_02444	2.92e-233	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
IOKFKOHM_02445	1.84e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
IOKFKOHM_02446	1.48e-197	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOKFKOHM_02447	6.73e-216	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOKFKOHM_02448	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
IOKFKOHM_02449	8.09e-235	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOKFKOHM_02450	1.76e-233	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOKFKOHM_02451	4.51e-191	yjaZ	-	-	O	-	-	-	Zn-dependent protease
IOKFKOHM_02452	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOKFKOHM_02453	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOKFKOHM_02454	4.43e-30	yjzB	-	-	-	-	-	-	-
IOKFKOHM_02455	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
IOKFKOHM_02456	7.48e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
IOKFKOHM_02457	8.63e-131	yjaV	-	-	-	-	-	-	-
IOKFKOHM_02458	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
IOKFKOHM_02459	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IOKFKOHM_02460	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
IOKFKOHM_02461	8.62e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOKFKOHM_02462	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
IOKFKOHM_02463	5.48e-261	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IOKFKOHM_02464	6.59e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
IOKFKOHM_02465	1.27e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IOKFKOHM_02466	2.03e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOKFKOHM_02467	2.38e-251	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOKFKOHM_02468	1.32e-113	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
IOKFKOHM_02469	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
IOKFKOHM_02470	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
IOKFKOHM_02471	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
IOKFKOHM_02472	1.45e-184	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IOKFKOHM_02473	5.29e-199	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IOKFKOHM_02474	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
IOKFKOHM_02475	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
IOKFKOHM_02476	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOKFKOHM_02477	3.72e-201	yitS	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02478	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IOKFKOHM_02479	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
IOKFKOHM_02480	5.02e-119	-	-	-	-	-	-	-	-
IOKFKOHM_02481	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOKFKOHM_02482	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IOKFKOHM_02483	1.17e-217	-	-	-	-	-	-	-	-
IOKFKOHM_02484	4.16e-122	-	-	-	-	-	-	-	-
IOKFKOHM_02485	3.08e-201	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
IOKFKOHM_02486	1.75e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
IOKFKOHM_02487	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IOKFKOHM_02488	8.44e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOKFKOHM_02489	2.39e-192	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOKFKOHM_02490	8.28e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_02491	1.02e-281	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IOKFKOHM_02492	6.62e-140	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOKFKOHM_02493	1.75e-179	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
IOKFKOHM_02494	1.01e-157	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
IOKFKOHM_02495	1.58e-183	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IOKFKOHM_02496	3.23e-294	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IOKFKOHM_02497	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IOKFKOHM_02498	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOKFKOHM_02499	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
IOKFKOHM_02500	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOKFKOHM_02501	5.19e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
IOKFKOHM_02502	9.94e-120	yisT	-	-	S	-	-	-	DinB family
IOKFKOHM_02503	9.59e-245	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IOKFKOHM_02504	8.71e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOKFKOHM_02505	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02506	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
IOKFKOHM_02507	3.44e-142	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
IOKFKOHM_02508	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IOKFKOHM_02509	1.44e-129	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
IOKFKOHM_02510	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOKFKOHM_02511	4.14e-74	yisL	-	-	S	-	-	-	UPF0344 protein
IOKFKOHM_02512	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IOKFKOHM_02513	3.25e-223	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IOKFKOHM_02514	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IOKFKOHM_02515	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
IOKFKOHM_02516	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
IOKFKOHM_02517	6.09e-95	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
IOKFKOHM_02518	6.07e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
IOKFKOHM_02519	2.27e-85	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
IOKFKOHM_02520	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
IOKFKOHM_02521	6.4e-65	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
IOKFKOHM_02522	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
IOKFKOHM_02523	3.84e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IOKFKOHM_02524	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IOKFKOHM_02525	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
IOKFKOHM_02526	1.09e-100	yhjR	-	-	S	-	-	-	Rubrerythrin
IOKFKOHM_02527	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
IOKFKOHM_02528	1.45e-262	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOKFKOHM_02529	2.39e-257	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
IOKFKOHM_02530	5.09e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02531	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IOKFKOHM_02532	8.81e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
IOKFKOHM_02533	9.38e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IOKFKOHM_02534	3.5e-269	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
IOKFKOHM_02537	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_02538	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
IOKFKOHM_02539	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOKFKOHM_02540	2.82e-140	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
IOKFKOHM_02541	3.4e-77	yhjD	-	-	-	-	-	-	-
IOKFKOHM_02542	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IOKFKOHM_02543	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOKFKOHM_02544	3.27e-53	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
IOKFKOHM_02545	2.55e-216	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOKFKOHM_02546	6.29e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
IOKFKOHM_02547	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
IOKFKOHM_02548	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_02549	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IOKFKOHM_02550	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
IOKFKOHM_02551	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IOKFKOHM_02552	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IOKFKOHM_02553	6.04e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IOKFKOHM_02554	1.13e-139	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
IOKFKOHM_02555	3.23e-222	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IOKFKOHM_02556	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
IOKFKOHM_02557	7.28e-101	-	-	-	K	-	-	-	acetyltransferase
IOKFKOHM_02558	1.7e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOKFKOHM_02559	6.5e-306	yhfN	-	-	O	-	-	-	Peptidase M48
IOKFKOHM_02560	2.78e-85	yhfM	-	-	-	-	-	-	-
IOKFKOHM_02561	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IOKFKOHM_02562	1.01e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
IOKFKOHM_02563	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IOKFKOHM_02564	2.82e-181	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IOKFKOHM_02565	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOKFKOHM_02566	1.53e-93	-	-	-	S	-	-	-	ASCH
IOKFKOHM_02567	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
IOKFKOHM_02568	3.8e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
IOKFKOHM_02569	1.77e-236	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOKFKOHM_02570	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
IOKFKOHM_02571	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_02572	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IOKFKOHM_02573	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IOKFKOHM_02574	6.13e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IOKFKOHM_02575	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IOKFKOHM_02576	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IOKFKOHM_02577	2.87e-44	-	-	-	C	-	-	-	Rubrerythrin
IOKFKOHM_02578	2.21e-311	yhfA	-	-	C	-	-	-	membrane
IOKFKOHM_02579	2.19e-291	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IOKFKOHM_02580	2.89e-161	ecsC	-	-	S	-	-	-	EcsC protein family
IOKFKOHM_02581	2.55e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IOKFKOHM_02582	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
IOKFKOHM_02583	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IOKFKOHM_02584	7.5e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOKFKOHM_02585	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
IOKFKOHM_02586	9.66e-30	-	-	-	-	-	-	-	-
IOKFKOHM_02587	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
IOKFKOHM_02588	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
IOKFKOHM_02589	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
IOKFKOHM_02590	5.71e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
IOKFKOHM_02591	4.7e-161	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOKFKOHM_02592	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
IOKFKOHM_02593	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
IOKFKOHM_02594	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IOKFKOHM_02595	8.36e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
IOKFKOHM_02596	3.4e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IOKFKOHM_02597	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
IOKFKOHM_02598	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
IOKFKOHM_02599	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IOKFKOHM_02600	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
IOKFKOHM_02601	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
IOKFKOHM_02602	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_02603	1.73e-48	yfhS	-	-	-	-	-	-	-
IOKFKOHM_02604	1.31e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
IOKFKOHM_02605	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
IOKFKOHM_02606	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IOKFKOHM_02607	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOKFKOHM_02608	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
IOKFKOHM_02609	5.4e-67	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
IOKFKOHM_02610	1.91e-114	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
IOKFKOHM_02611	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
IOKFKOHM_02612	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
IOKFKOHM_02613	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
IOKFKOHM_02615	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
IOKFKOHM_02616	3.25e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IOKFKOHM_02617	3.79e-220	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
IOKFKOHM_02619	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
IOKFKOHM_02620	2.36e-137	yfhC	-	-	C	-	-	-	nitroreductase
IOKFKOHM_02621	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
IOKFKOHM_02622	5.18e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_02623	2.57e-155	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_02624	8.07e-233	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOKFKOHM_02625	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOKFKOHM_02626	1.43e-101	yfiV	-	-	K	-	-	-	transcriptional
IOKFKOHM_02627	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
IOKFKOHM_02628	6.37e-125	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
IOKFKOHM_02629	1.57e-265	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
IOKFKOHM_02630	2.71e-137	yfiR	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02631	3.12e-251	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IOKFKOHM_02632	1.3e-126	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IOKFKOHM_02633	1.89e-128	padR	-	-	K	-	-	-	transcriptional
IOKFKOHM_02634	1.82e-257	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IOKFKOHM_02635	3.08e-266	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOKFKOHM_02636	2.53e-213	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_02637	1.74e-145	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
IOKFKOHM_02638	5.09e-274	baeS	-	-	T	-	-	-	Histidine kinase
IOKFKOHM_02640	6.76e-291	-	-	-	S	-	-	-	Oxidoreductase
IOKFKOHM_02641	2.23e-233	-	-	-	G	-	-	-	Xylose isomerase
IOKFKOHM_02642	0.0	yfiG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOKFKOHM_02643	1.28e-228	-	-	-	K	ko:K02099	-	ko00000,ko03000	AraC-like ligand binding domain
IOKFKOHM_02644	4.21e-208	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IOKFKOHM_02645	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
IOKFKOHM_02646	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOKFKOHM_02647	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOKFKOHM_02648	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
IOKFKOHM_02649	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_02650	2.49e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IOKFKOHM_02651	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IOKFKOHM_02652	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
IOKFKOHM_02653	1.62e-239	yfjB	-	-	-	-	-	-	-
IOKFKOHM_02654	4.33e-161	yfjC	-	-	-	-	-	-	-
IOKFKOHM_02655	5.95e-113	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
IOKFKOHM_02656	1.38e-72	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
IOKFKOHM_02657	2.75e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
IOKFKOHM_02658	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
IOKFKOHM_02659	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOKFKOHM_02660	3.67e-259	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOKFKOHM_02661	2.53e-240	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOKFKOHM_02662	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOKFKOHM_02664	4.55e-109	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOKFKOHM_02665	7.83e-240	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOKFKOHM_02666	4.32e-59	-	-	-	S	-	-	-	YfzA-like protein
IOKFKOHM_02667	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOKFKOHM_02668	1.31e-212	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IOKFKOHM_02669	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
IOKFKOHM_02670	7.33e-189	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IOKFKOHM_02671	5.95e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
IOKFKOHM_02672	3.26e-36	yfjT	-	-	-	-	-	-	-
IOKFKOHM_02673	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
IOKFKOHM_02674	4.97e-188	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
IOKFKOHM_02675	2.14e-188	yfkD	-	-	S	-	-	-	YfkD-like protein
IOKFKOHM_02676	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
IOKFKOHM_02677	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_02678	1.64e-12	-	-	-	-	-	-	-	-
IOKFKOHM_02679	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IOKFKOHM_02680	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
IOKFKOHM_02681	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOKFKOHM_02682	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
IOKFKOHM_02683	5.94e-264	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_02684	7.78e-114	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IOKFKOHM_02685	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOKFKOHM_02686	5.27e-161	frp	-	-	C	-	-	-	nitroreductase
IOKFKOHM_02687	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
IOKFKOHM_02688	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IOKFKOHM_02689	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_02690	1.29e-30	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IOKFKOHM_02691	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
IOKFKOHM_02692	3.81e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
IOKFKOHM_02693	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IOKFKOHM_02694	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IOKFKOHM_02695	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IOKFKOHM_02696	3.63e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IOKFKOHM_02697	6.9e-27	yflI	-	-	-	-	-	-	-
IOKFKOHM_02698	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
IOKFKOHM_02699	5.91e-158	yflK	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02700	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IOKFKOHM_02701	5.59e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IOKFKOHM_02702	1.7e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IOKFKOHM_02703	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IOKFKOHM_02704	1.62e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
IOKFKOHM_02705	2.68e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IOKFKOHM_02706	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IOKFKOHM_02707	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IOKFKOHM_02708	8.2e-306	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
IOKFKOHM_02709	9.89e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
IOKFKOHM_02710	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
IOKFKOHM_02711	2.76e-219	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IOKFKOHM_02712	4.72e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_02713	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_02714	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOKFKOHM_02715	2.84e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
IOKFKOHM_02716	1.86e-98	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
IOKFKOHM_02717	1.4e-261	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
IOKFKOHM_02718	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOKFKOHM_02719	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
IOKFKOHM_02720	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
IOKFKOHM_02721	4.39e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
IOKFKOHM_02722	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOKFKOHM_02723	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
IOKFKOHM_02724	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOKFKOHM_02725	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
IOKFKOHM_02726	2.05e-165	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOKFKOHM_02727	7.24e-267	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_02728	1.35e-242	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IOKFKOHM_02729	6.7e-284	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
IOKFKOHM_02730	9.02e-228	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IOKFKOHM_02731	7.94e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
IOKFKOHM_02732	4.01e-186	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
IOKFKOHM_02733	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IOKFKOHM_02734	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IOKFKOHM_02735	3.53e-254	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
IOKFKOHM_02736	2.08e-264	yetM	-	-	CH	-	-	-	FAD binding domain
IOKFKOHM_02737	3.9e-116	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_02738	8.72e-195	-	-	-	EG	-	-	-	EamA-like transporter family
IOKFKOHM_02739	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IOKFKOHM_02740	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
IOKFKOHM_02741	3.59e-184	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOKFKOHM_02742	1.93e-122	-	-	GH19	M	ko:K03791	-	ko00000	Lysin motif
IOKFKOHM_02743	2.61e-73	-	-	-	-	-	-	-	-
IOKFKOHM_02744	6.26e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOKFKOHM_02745	9.75e-228	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
IOKFKOHM_02747	3.91e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IOKFKOHM_02748	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOKFKOHM_02749	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
IOKFKOHM_02750	6.15e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IOKFKOHM_02751	2.25e-59	ybfN	-	-	-	-	-	-	-
IOKFKOHM_02752	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
IOKFKOHM_02753	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_02754	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
IOKFKOHM_02755	6.04e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOKFKOHM_02756	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_02757	1.01e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOKFKOHM_02758	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IOKFKOHM_02760	3.29e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IOKFKOHM_02761	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IOKFKOHM_02762	1.83e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
IOKFKOHM_02763	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IOKFKOHM_02764	4.35e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IOKFKOHM_02765	6.85e-292	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_02766	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
IOKFKOHM_02767	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
IOKFKOHM_02768	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOKFKOHM_02769	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_02770	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IOKFKOHM_02771	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
IOKFKOHM_02772	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IOKFKOHM_02773	3.51e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
IOKFKOHM_02774	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
IOKFKOHM_02775	4.05e-215	eamA1	-	-	EG	-	-	-	spore germination
IOKFKOHM_02776	5.28e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_02777	4.37e-214	ycbM	-	-	T	-	-	-	Histidine kinase
IOKFKOHM_02778	3.21e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_02779	4.96e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
IOKFKOHM_02780	2.21e-76	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IOKFKOHM_02781	5.22e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
IOKFKOHM_02782	6.1e-171	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
IOKFKOHM_02783	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
IOKFKOHM_02784	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IOKFKOHM_02785	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IOKFKOHM_02786	2.32e-152	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOKFKOHM_02787	6.62e-257	ycbU	-	-	E	-	-	-	Selenocysteine lyase
IOKFKOHM_02788	2.87e-308	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IOKFKOHM_02789	6.54e-132	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IOKFKOHM_02790	8.37e-258	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IOKFKOHM_02791	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IOKFKOHM_02792	4.32e-78	-	-	-	S	-	-	-	RDD family
IOKFKOHM_02793	6.84e-253	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
IOKFKOHM_02794	9.56e-217	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IOKFKOHM_02795	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IOKFKOHM_02796	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOKFKOHM_02797	9.75e-258	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IOKFKOHM_02798	1.95e-221	yccK	-	-	C	-	-	-	Aldo keto reductase
IOKFKOHM_02799	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
IOKFKOHM_02800	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_02801	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_02802	1.26e-121	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IOKFKOHM_02803	1.16e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
IOKFKOHM_02804	6.85e-180	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
IOKFKOHM_02805	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IOKFKOHM_02806	2.27e-220	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOKFKOHM_02807	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IOKFKOHM_02808	1.88e-172	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IOKFKOHM_02809	4.19e-238	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOKFKOHM_02810	3.08e-140	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
IOKFKOHM_02811	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IOKFKOHM_02812	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IOKFKOHM_02813	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
IOKFKOHM_02814	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
IOKFKOHM_02815	4.21e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
IOKFKOHM_02816	2.7e-278	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
IOKFKOHM_02817	3.34e-267	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IOKFKOHM_02818	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOKFKOHM_02819	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
IOKFKOHM_02820	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IOKFKOHM_02821	1.16e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IOKFKOHM_02822	1.97e-276	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
IOKFKOHM_02823	0.0	ycgA	-	-	S	-	-	-	Membrane
IOKFKOHM_02824	2.72e-105	ycgB	-	-	-	-	-	-	-
IOKFKOHM_02825	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
IOKFKOHM_02826	1.69e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IOKFKOHM_02827	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IOKFKOHM_02828	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
IOKFKOHM_02829	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_02830	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
IOKFKOHM_02831	5.71e-190	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
IOKFKOHM_02832	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOKFKOHM_02833	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
IOKFKOHM_02834	7.44e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOKFKOHM_02835	1.08e-139	tmrB	-	-	S	-	-	-	AAA domain
IOKFKOHM_02836	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IOKFKOHM_02837	1.29e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
IOKFKOHM_02838	2.05e-230	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
IOKFKOHM_02839	1.15e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
IOKFKOHM_02840	7.76e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
IOKFKOHM_02841	2.1e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IOKFKOHM_02842	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IOKFKOHM_02843	2.64e-316	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOKFKOHM_02844	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
IOKFKOHM_02845	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
IOKFKOHM_02846	9.14e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
IOKFKOHM_02847	3.07e-205	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
IOKFKOHM_02848	8.53e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IOKFKOHM_02849	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IOKFKOHM_02850	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
IOKFKOHM_02851	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IOKFKOHM_02852	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOKFKOHM_02853	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
IOKFKOHM_02854	2.24e-282	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IOKFKOHM_02855	1.05e-222	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
IOKFKOHM_02856	2.56e-141	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IOKFKOHM_02857	3.92e-290	yciC	-	-	S	-	-	-	GTPases (G3E family)
IOKFKOHM_02858	4.96e-148	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IOKFKOHM_02859	3.76e-187	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IOKFKOHM_02861	4.82e-67	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
IOKFKOHM_02862	1.29e-58	-	-	-	K	-	-	-	MarR family
IOKFKOHM_02863	9e-32	-	-	-	-	-	-	-	-
IOKFKOHM_02864	4.7e-154	-	-	-	S	-	-	-	AAA domain
IOKFKOHM_02865	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOKFKOHM_02866	5.81e-92	nin	-	-	S	-	-	-	Competence protein J (ComJ)
IOKFKOHM_02867	7.94e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IOKFKOHM_02868	4.34e-267	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOKFKOHM_02869	6.55e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
IOKFKOHM_02870	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
IOKFKOHM_02871	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
IOKFKOHM_02872	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOKFKOHM_02873	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOKFKOHM_02874	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
IOKFKOHM_02875	4.54e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOKFKOHM_02876	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
IOKFKOHM_02877	1.71e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOKFKOHM_02878	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOKFKOHM_02879	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOKFKOHM_02880	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOKFKOHM_02881	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
IOKFKOHM_02882	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOKFKOHM_02883	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOKFKOHM_02884	2.9e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IOKFKOHM_02885	2.58e-192	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IOKFKOHM_02886	2.18e-96	-	-	-	S	-	-	-	Bacterial PH domain
IOKFKOHM_02887	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
IOKFKOHM_02888	1.32e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOKFKOHM_02889	1.3e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
IOKFKOHM_02890	6.23e-226	yyaD	-	-	S	-	-	-	Membrane
IOKFKOHM_02891	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02892	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOKFKOHM_02893	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOKFKOHM_02894	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IOKFKOHM_02895	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOKFKOHM_02896	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOKFKOHM_02897	3.43e-186	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IOKFKOHM_02898	1.18e-227	ccpB	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02899	7.2e-90	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOKFKOHM_02900	6.32e-128	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
IOKFKOHM_02901	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
IOKFKOHM_02902	5.15e-216	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOKFKOHM_02903	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
IOKFKOHM_02904	1.81e-138	yyaP	-	-	H	-	-	-	RibD C-terminal domain
IOKFKOHM_02905	1.82e-86	-	-	-	S	-	-	-	YjbR
IOKFKOHM_02906	1.64e-120	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
IOKFKOHM_02907	4.99e-124	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
IOKFKOHM_02908	1.77e-91	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOKFKOHM_02909	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
IOKFKOHM_02910	2.52e-163	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IOKFKOHM_02911	3.4e-85	-	-	-	S	-	-	-	SnoaL-like domain
IOKFKOHM_02912	2.49e-184	-	-	-	-	-	-	-	-
IOKFKOHM_02913	9.88e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
IOKFKOHM_02914	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_02916	1.11e-90	-	-	-	-	-	-	-	-
IOKFKOHM_02917	1.4e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
IOKFKOHM_02918	6.68e-90	yybR	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_02919	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
IOKFKOHM_02921	5.23e-205	yybS	-	-	S	-	-	-	membrane
IOKFKOHM_02922	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IOKFKOHM_02923	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IOKFKOHM_02924	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOKFKOHM_02925	2.83e-281	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
IOKFKOHM_02926	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
IOKFKOHM_02928	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IOKFKOHM_02929	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IOKFKOHM_02930	5.69e-100	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOKFKOHM_02931	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOKFKOHM_02936	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_02937	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_02938	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02939	6.94e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_02940	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IOKFKOHM_02941	2.32e-279	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOKFKOHM_02942	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IOKFKOHM_02943	2.31e-54	sdpR	-	-	K	-	-	-	transcriptional
IOKFKOHM_02944	3.95e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IOKFKOHM_02945	6.81e-19	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IOKFKOHM_02946	4.85e-119	-	-	-	-	-	-	-	-
IOKFKOHM_02947	5.82e-20	-	-	-	-	-	-	-	-
IOKFKOHM_02948	1.01e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
IOKFKOHM_02949	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IOKFKOHM_02950	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IOKFKOHM_02952	8.7e-239	-	-	-	S	-	-	-	aspartate phosphatase
IOKFKOHM_02953	3.04e-110	yycN	-	-	K	-	-	-	Acetyltransferase
IOKFKOHM_02954	7.97e-168	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IOKFKOHM_02955	1.34e-260	yycP	-	-	-	-	-	-	-
IOKFKOHM_02956	1.58e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IOKFKOHM_02958	2.58e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IOKFKOHM_02959	3.31e-89	-	-	-	-	-	-	-	-
IOKFKOHM_02961	2.48e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOKFKOHM_02963	8.92e-190	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	DNA methylase
IOKFKOHM_02964	3.02e-189	-	-	-	L	-	-	-	Putative RNA methylase family UPF0020
IOKFKOHM_02965	1.04e-147	-	-	-	V	-	-	-	HNH endonuclease
IOKFKOHM_02966	1.93e-12	-	-	-	-	-	-	-	-
IOKFKOHM_02967	2.15e-33	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
IOKFKOHM_02968	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
IOKFKOHM_02969	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOKFKOHM_02970	9.5e-153	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IOKFKOHM_02971	1.95e-159	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_02972	1.19e-24	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_02973	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOKFKOHM_02974	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
IOKFKOHM_02975	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
IOKFKOHM_02976	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOKFKOHM_02977	1.18e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IOKFKOHM_02978	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IOKFKOHM_02979	1.27e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
IOKFKOHM_02980	1.16e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IOKFKOHM_02981	1.47e-244	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
IOKFKOHM_02982	1.27e-152	yxaC	-	-	M	-	-	-	effector of murein hydrolase
IOKFKOHM_02983	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
IOKFKOHM_02984	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_02985	1.75e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOKFKOHM_02986	2.75e-130	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IOKFKOHM_02987	1.55e-252	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
IOKFKOHM_02988	2.88e-290	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IOKFKOHM_02989	2.83e-99	yxaI	-	-	S	-	-	-	membrane protein domain
IOKFKOHM_02990	2.78e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
IOKFKOHM_02991	1.06e-33	yxaI	-	-	S	-	-	-	membrane protein domain
IOKFKOHM_02992	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOKFKOHM_02993	6.07e-274	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOKFKOHM_02994	1.14e-190	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOKFKOHM_02996	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
IOKFKOHM_02997	1.02e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOKFKOHM_02998	3.02e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
IOKFKOHM_03000	2.04e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IOKFKOHM_03001	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IOKFKOHM_03002	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOKFKOHM_03003	9.89e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IOKFKOHM_03004	6.81e-225	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IOKFKOHM_03005	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IOKFKOHM_03006	2.47e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IOKFKOHM_03007	2.32e-295	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
IOKFKOHM_03008	6.3e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IOKFKOHM_03009	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
IOKFKOHM_03010	1.54e-186	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IOKFKOHM_03011	1.57e-201	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IOKFKOHM_03012	8.03e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_03013	4.47e-230	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_03014	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_03015	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IOKFKOHM_03016	6.96e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IOKFKOHM_03017	1.23e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOKFKOHM_03018	6.79e-91	-	-	-	-	-	-	-	-
IOKFKOHM_03019	2.66e-28	yxeD	-	-	-	-	-	-	-
IOKFKOHM_03020	7.32e-42	yxeE	-	-	-	-	-	-	-
IOKFKOHM_03023	5.69e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
IOKFKOHM_03024	1.57e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IOKFKOHM_03025	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOKFKOHM_03026	3.63e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOKFKOHM_03027	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOKFKOHM_03028	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IOKFKOHM_03029	3.94e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_03030	2.77e-270	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IOKFKOHM_03031	4.16e-314	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
IOKFKOHM_03032	1.49e-253	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
IOKFKOHM_03033	1.51e-196	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
IOKFKOHM_03034	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IOKFKOHM_03035	3.38e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOKFKOHM_03036	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOKFKOHM_03037	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
IOKFKOHM_03038	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IOKFKOHM_03039	1.97e-230	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IOKFKOHM_03040	2.24e-299	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
IOKFKOHM_03041	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IOKFKOHM_03042	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
IOKFKOHM_03043	2.01e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IOKFKOHM_03044	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IOKFKOHM_03045	1.78e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
IOKFKOHM_03046	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
IOKFKOHM_03047	1.66e-270	-	-	-	S	-	-	-	nuclease activity
IOKFKOHM_03049	1.31e-118	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
IOKFKOHM_03050	9.21e-44	-	-	-	-	-	-	-	-
IOKFKOHM_03051	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_03052	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOKFKOHM_03053	8.16e-93	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
IOKFKOHM_03054	3.58e-211	yxxF	-	-	EG	-	-	-	EamA-like transporter family
IOKFKOHM_03055	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
IOKFKOHM_03056	1.16e-19	yxiJ	-	-	S	-	-	-	YxiJ-like protein
IOKFKOHM_03057	1.27e-69	-	-	-	-	-	-	-	-
IOKFKOHM_03059	6.44e-178	-	-	-	-	-	-	-	-
IOKFKOHM_03060	5.36e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
IOKFKOHM_03061	3.53e-100	-	-	-	-	-	-	-	-
IOKFKOHM_03062	1.28e-57	-	-	-	-	-	-	-	-
IOKFKOHM_03063	1.83e-86	yxiG	-	-	-	-	-	-	-
IOKFKOHM_03064	9.7e-68	yxxG	-	-	-	-	-	-	-
IOKFKOHM_03065	6.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
IOKFKOHM_03068	4.17e-174	-	-	-	-	-	-	-	-
IOKFKOHM_03069	4.6e-108	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
IOKFKOHM_03070	1.83e-43	-	-	-	-	-	-	-	-
IOKFKOHM_03073	1.42e-58	yxiJ	-	-	S	-	-	-	YxiJ-like protein
IOKFKOHM_03076	6.57e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
IOKFKOHM_03077	4.57e-71	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOKFKOHM_03078	4.79e-272	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOKFKOHM_03079	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IOKFKOHM_03080	2.56e-290	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
IOKFKOHM_03081	3.07e-142	-	-	-	-	-	-	-	-
IOKFKOHM_03082	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IOKFKOHM_03083	1.77e-183	bglS	-	-	M	-	-	-	licheninase activity
IOKFKOHM_03084	2.84e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IOKFKOHM_03085	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IOKFKOHM_03086	2.28e-63	yxiS	-	-	-	-	-	-	-
IOKFKOHM_03087	9.87e-132	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
IOKFKOHM_03088	1.72e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOKFKOHM_03089	6.94e-201	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
IOKFKOHM_03090	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
IOKFKOHM_03091	4.65e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IOKFKOHM_03092	6.9e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IOKFKOHM_03093	5.83e-176	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IOKFKOHM_03094	8.03e-278	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IOKFKOHM_03095	2.59e-278	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IOKFKOHM_03096	1.74e-112	yxjI	-	-	S	-	-	-	LURP-one-related
IOKFKOHM_03098	1.83e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IOKFKOHM_03099	2.69e-148	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
IOKFKOHM_03100	3.23e-257	-	-	-	T	-	-	-	Signal transduction histidine kinase
IOKFKOHM_03101	3.81e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
IOKFKOHM_03102	6.06e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IOKFKOHM_03103	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOKFKOHM_03104	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOKFKOHM_03105	1.93e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IOKFKOHM_03106	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOKFKOHM_03107	2.51e-197	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
IOKFKOHM_03109	0.0	-	-	-	O	-	-	-	Peptidase family M48
IOKFKOHM_03110	1.62e-309	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
IOKFKOHM_03111	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IOKFKOHM_03112	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
IOKFKOHM_03134	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOKFKOHM_03135	1.91e-261	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOKFKOHM_03136	3.72e-238	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
IOKFKOHM_03137	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IOKFKOHM_03138	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOKFKOHM_03139	1.97e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
IOKFKOHM_03140	1.06e-259	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
IOKFKOHM_03141	4.12e-275	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
IOKFKOHM_03142	1.7e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
IOKFKOHM_03144	7.47e-300	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
IOKFKOHM_03145	1.28e-229	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
IOKFKOHM_03146	3.23e-307	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOKFKOHM_03147	5.69e-195	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IOKFKOHM_03148	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IOKFKOHM_03149	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IOKFKOHM_03150	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IOKFKOHM_03151	1.34e-194	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IOKFKOHM_03152	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IOKFKOHM_03153	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IOKFKOHM_03154	4.98e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IOKFKOHM_03155	4.4e-216	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOKFKOHM_03156	1.97e-175	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IOKFKOHM_03157	1.29e-296	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IOKFKOHM_03158	2.77e-193	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IOKFKOHM_03159	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
IOKFKOHM_03160	6.66e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IOKFKOHM_03161	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IOKFKOHM_03162	1.44e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IOKFKOHM_03163	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IOKFKOHM_03164	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOKFKOHM_03165	6.79e-95	ytkA	-	-	S	-	-	-	YtkA-like
IOKFKOHM_03167	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IOKFKOHM_03168	3.2e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
IOKFKOHM_03169	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IOKFKOHM_03170	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IOKFKOHM_03171	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOKFKOHM_03172	1.87e-240	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IOKFKOHM_03173	5.48e-190	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IOKFKOHM_03174	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
IOKFKOHM_03175	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IOKFKOHM_03176	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOKFKOHM_03177	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IOKFKOHM_03178	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOKFKOHM_03179	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IOKFKOHM_03180	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
IOKFKOHM_03181	1.88e-273	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
IOKFKOHM_03182	3.91e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
IOKFKOHM_03183	1.93e-243	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
IOKFKOHM_03184	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
IOKFKOHM_03186	5.41e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
IOKFKOHM_03187	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_03188	1.72e-192	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IOKFKOHM_03189	5.43e-162	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
IOKFKOHM_03190	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_03191	1.98e-296	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IOKFKOHM_03192	9.07e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_03193	1.62e-232	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
IOKFKOHM_03194	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_03195	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
IOKFKOHM_03196	4.46e-56	yttA	-	-	S	-	-	-	Pfam Transposase IS66
IOKFKOHM_03197	1.21e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
IOKFKOHM_03198	1.1e-182	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IOKFKOHM_03199	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
IOKFKOHM_03200	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IOKFKOHM_03201	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
IOKFKOHM_03202	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IOKFKOHM_03203	8.93e-185	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IOKFKOHM_03204	4.75e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOKFKOHM_03205	3.66e-312	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOKFKOHM_03206	4.56e-244	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_03207	2.66e-218	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
IOKFKOHM_03208	9.13e-179	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IOKFKOHM_03209	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IOKFKOHM_03210	1.63e-278	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOKFKOHM_03211	8.91e-157	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IOKFKOHM_03212	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IOKFKOHM_03213	2.95e-284	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOKFKOHM_03214	1.28e-177	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
IOKFKOHM_03215	3.58e-192	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IOKFKOHM_03216	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IOKFKOHM_03217	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_03218	2.27e-221	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IOKFKOHM_03219	2.23e-286	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IOKFKOHM_03220	5.81e-95	yteS	-	-	G	-	-	-	transport
IOKFKOHM_03221	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
IOKFKOHM_03222	1.09e-149	yteU	-	-	S	-	-	-	Integral membrane protein
IOKFKOHM_03223	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
IOKFKOHM_03224	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
IOKFKOHM_03225	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
IOKFKOHM_03226	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOKFKOHM_03227	2.13e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOKFKOHM_03228	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
IOKFKOHM_03229	4.65e-167	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOKFKOHM_03230	2.89e-254	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
IOKFKOHM_03231	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IOKFKOHM_03232	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
IOKFKOHM_03233	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IOKFKOHM_03234	2.13e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IOKFKOHM_03235	4.92e-212	ytlQ	-	-	-	-	-	-	-
IOKFKOHM_03236	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOKFKOHM_03237	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IOKFKOHM_03238	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
IOKFKOHM_03239	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
IOKFKOHM_03240	1.25e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOKFKOHM_03241	1.06e-190	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IOKFKOHM_03242	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IOKFKOHM_03243	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
IOKFKOHM_03244	9.11e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
IOKFKOHM_03245	9.97e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
IOKFKOHM_03246	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
IOKFKOHM_03247	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
IOKFKOHM_03248	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOKFKOHM_03249	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOKFKOHM_03250	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IOKFKOHM_03251	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOKFKOHM_03252	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
IOKFKOHM_03253	1.51e-69	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
IOKFKOHM_03254	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IOKFKOHM_03255	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IOKFKOHM_03256	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IOKFKOHM_03257	1.31e-160	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IOKFKOHM_03258	2.58e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
IOKFKOHM_03259	1.45e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
IOKFKOHM_03260	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IOKFKOHM_03261	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IOKFKOHM_03262	6.47e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOKFKOHM_03264	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOKFKOHM_03265	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
IOKFKOHM_03266	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IOKFKOHM_03267	2.94e-142	yttP	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_03268	1.07e-197	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IOKFKOHM_03269	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOKFKOHM_03270	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOKFKOHM_03271	5.3e-264	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IOKFKOHM_03272	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOKFKOHM_03273	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IOKFKOHM_03274	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IOKFKOHM_03275	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
IOKFKOHM_03276	2.4e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOKFKOHM_03277	2.39e-230	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
IOKFKOHM_03278	3.92e-110	yteJ	-	-	S	-	-	-	RDD family
IOKFKOHM_03279	3.4e-148	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
IOKFKOHM_03280	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
IOKFKOHM_03281	7.88e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOKFKOHM_03282	1.79e-222	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
IOKFKOHM_03284	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOKFKOHM_03285	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
IOKFKOHM_03286	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOKFKOHM_03287	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IOKFKOHM_03289	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_03290	4.53e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
IOKFKOHM_03291	1.37e-220	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
IOKFKOHM_03292	8.39e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IOKFKOHM_03293	7.48e-194	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOKFKOHM_03294	6.27e-187	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOKFKOHM_03295	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOKFKOHM_03296	7.89e-154	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOKFKOHM_03297	2.21e-181	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IOKFKOHM_03298	1.52e-237	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOKFKOHM_03299	5.26e-63	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
IOKFKOHM_03300	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOKFKOHM_03301	1.69e-166	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
IOKFKOHM_03302	1.58e-301	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IOKFKOHM_03303	6.14e-204	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOKFKOHM_03304	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
IOKFKOHM_03305	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
IOKFKOHM_03306	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
IOKFKOHM_03307	1.15e-39	-	-	-	-	-	-	-	-
IOKFKOHM_03308	5.12e-112	ytrI	-	-	-	-	-	-	-
IOKFKOHM_03309	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
IOKFKOHM_03310	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IOKFKOHM_03311	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IOKFKOHM_03312	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOKFKOHM_03313	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IOKFKOHM_03314	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOKFKOHM_03315	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IOKFKOHM_03316	3.16e-80	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
IOKFKOHM_03317	2.24e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
IOKFKOHM_03318	9.38e-95	ytwI	-	-	S	-	-	-	membrane
IOKFKOHM_03319	3.34e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IOKFKOHM_03320	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
IOKFKOHM_03321	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
IOKFKOHM_03322	3.27e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOKFKOHM_03323	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
IOKFKOHM_03324	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOKFKOHM_03325	3.88e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOKFKOHM_03326	5.63e-137	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IOKFKOHM_03327	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOKFKOHM_03328	4.54e-205	ytbE	-	-	S	-	-	-	reductase
IOKFKOHM_03329	1.12e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
IOKFKOHM_03330	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_03331	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOKFKOHM_03332	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IOKFKOHM_03333	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOKFKOHM_03334	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
IOKFKOHM_03335	1.22e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IOKFKOHM_03336	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
IOKFKOHM_03337	5.98e-206	ytxC	-	-	S	-	-	-	YtxC-like family
IOKFKOHM_03338	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOKFKOHM_03339	1.98e-189	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IOKFKOHM_03340	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_03341	3.25e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
IOKFKOHM_03342	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IOKFKOHM_03343	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IOKFKOHM_03345	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOKFKOHM_03346	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IOKFKOHM_03347	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOKFKOHM_03348	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
IOKFKOHM_03349	1.89e-87	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
IOKFKOHM_03350	3.57e-261	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
IOKFKOHM_03351	9.92e-242	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IOKFKOHM_03352	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IOKFKOHM_03353	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
IOKFKOHM_03354	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IOKFKOHM_03355	6.06e-187	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
IOKFKOHM_03356	3.05e-281	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IOKFKOHM_03357	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IOKFKOHM_03358	1.94e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IOKFKOHM_03359	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
IOKFKOHM_03360	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
IOKFKOHM_03361	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
IOKFKOHM_03362	8.42e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
IOKFKOHM_03363	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
IOKFKOHM_03364	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
IOKFKOHM_03365	2.51e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
IOKFKOHM_03366	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
IOKFKOHM_03367	3.13e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOKFKOHM_03368	7.36e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOKFKOHM_03369	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOKFKOHM_03370	2.96e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOKFKOHM_03371	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IOKFKOHM_03372	3.12e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
IOKFKOHM_03373	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
IOKFKOHM_03374	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOKFKOHM_03375	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
IOKFKOHM_03376	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IOKFKOHM_03377	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_03378	3.12e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
IOKFKOHM_03379	3.01e-178	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
IOKFKOHM_03380	2.89e-226	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
IOKFKOHM_03382	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
IOKFKOHM_03383	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IOKFKOHM_03384	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOKFKOHM_03385	3.79e-273	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOKFKOHM_03386	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IOKFKOHM_03387	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
IOKFKOHM_03388	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IOKFKOHM_03389	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IOKFKOHM_03390	1.78e-97	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
IOKFKOHM_03391	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_03392	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOKFKOHM_03393	4.49e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOKFKOHM_03394	1.14e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
IOKFKOHM_03395	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IOKFKOHM_03396	3.56e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOKFKOHM_03397	9.55e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IOKFKOHM_03399	1.25e-176	ysnF	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_03401	1.59e-101	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
IOKFKOHM_03402	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IOKFKOHM_03403	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IOKFKOHM_03404	3.91e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOKFKOHM_03405	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IOKFKOHM_03406	4.3e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IOKFKOHM_03407	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOKFKOHM_03408	2.98e-147	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOKFKOHM_03409	3.19e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
IOKFKOHM_03410	5.13e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOKFKOHM_03411	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOKFKOHM_03412	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
IOKFKOHM_03413	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IOKFKOHM_03414	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IOKFKOHM_03415	4.77e-116	ysxD	-	-	-	-	-	-	-
IOKFKOHM_03416	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IOKFKOHM_03417	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
IOKFKOHM_03418	6.27e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IOKFKOHM_03419	4.13e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IOKFKOHM_03420	2.14e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
IOKFKOHM_03421	1.44e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IOKFKOHM_03422	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
IOKFKOHM_03423	2.39e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IOKFKOHM_03424	1.53e-35	-	-	-	-	-	-	-	-
IOKFKOHM_03425	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOKFKOHM_03426	5.8e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IOKFKOHM_03427	3.15e-109	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IOKFKOHM_03428	6.07e-211	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
IOKFKOHM_03429	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
IOKFKOHM_03430	3.36e-87	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
IOKFKOHM_03431	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IOKFKOHM_03432	1.59e-242	yhdN	-	-	C	-	-	-	Aldo keto reductase
IOKFKOHM_03433	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_03434	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
IOKFKOHM_03435	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
IOKFKOHM_03436	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOKFKOHM_03437	3.29e-111	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOKFKOHM_03438	2.23e-202	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOKFKOHM_03439	4.29e-310	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IOKFKOHM_03440	5.36e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
IOKFKOHM_03441	1.85e-119	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_03442	4.71e-41	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOKFKOHM_03443	1.3e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IOKFKOHM_03444	4.05e-209	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_03445	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IOKFKOHM_03446	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IOKFKOHM_03447	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
IOKFKOHM_03448	2.15e-306	ygxB	-	-	M	-	-	-	Conserved TM helix
IOKFKOHM_03449	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
IOKFKOHM_03450	4.06e-271	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IOKFKOHM_03451	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IOKFKOHM_03452	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
IOKFKOHM_03453	1.9e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
IOKFKOHM_03454	5.44e-144	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOKFKOHM_03455	1.54e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_03456	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
IOKFKOHM_03457	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IOKFKOHM_03458	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOKFKOHM_03459	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOKFKOHM_03460	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IOKFKOHM_03461	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOKFKOHM_03462	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IOKFKOHM_03463	1.24e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
IOKFKOHM_03464	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IOKFKOHM_03465	2.47e-88	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
IOKFKOHM_03466	1.67e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IOKFKOHM_03467	1.78e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IOKFKOHM_03468	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOKFKOHM_03469	9.74e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
IOKFKOHM_03470	4.15e-143	yhcP	-	-	-	-	-	-	-
IOKFKOHM_03471	1.57e-60	yhcP	-	-	-	-	-	-	-
IOKFKOHM_03472	2.69e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOKFKOHM_03473	4.4e-68	yhcM	-	-	-	-	-	-	-
IOKFKOHM_03474	3.22e-65	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOKFKOHM_03475	1.19e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
IOKFKOHM_03476	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOKFKOHM_03477	5.82e-250	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
IOKFKOHM_03478	3.09e-167	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IOKFKOHM_03479	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IOKFKOHM_03480	1.99e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOKFKOHM_03481	1.25e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_03482	3.38e-158	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_03483	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_03484	1.03e-69	-	-	-	-	-	-	-	-
IOKFKOHM_03485	3.95e-59	yhcC	-	-	-	-	-	-	-
IOKFKOHM_03486	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
IOKFKOHM_03487	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IOKFKOHM_03488	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
IOKFKOHM_03489	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
IOKFKOHM_03490	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
IOKFKOHM_03491	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
IOKFKOHM_03492	2.34e-102	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IOKFKOHM_03493	1.32e-95	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IOKFKOHM_03494	3.4e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
IOKFKOHM_03495	3.78e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOKFKOHM_03496	2.77e-225	yhbB	-	-	S	-	-	-	Putative amidase domain
IOKFKOHM_03497	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IOKFKOHM_03498	5.51e-147	yhzB	-	-	S	-	-	-	B3/4 domain
IOKFKOHM_03500	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_03501	2.79e-102	ygaO	-	-	-	-	-	-	-
IOKFKOHM_03502	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOKFKOHM_03504	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
IOKFKOHM_03505	3.96e-188	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IOKFKOHM_03506	2.82e-216	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
IOKFKOHM_03507	2.58e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IOKFKOHM_03508	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IOKFKOHM_03510	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IOKFKOHM_03511	4.02e-172	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
IOKFKOHM_03512	3.88e-37	-	-	-	-	-	-	-	-
IOKFKOHM_03513	2.22e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
IOKFKOHM_03530	2.07e-290	-	-	-	S	-	-	-	Recombinase
IOKFKOHM_03531	9.93e-94	-	-	-	S	-	-	-	Pfam:Peptidase_M78
IOKFKOHM_03532	8.53e-84	-	-	-	S	-	-	-	sequence-specific DNA binding
IOKFKOHM_03533	6.56e-12	-	-	-	K	-	-	-	helix-turn-helix
IOKFKOHM_03536	2.48e-64	-	-	-	-	-	-	-	-
IOKFKOHM_03537	3e-13	-	-	-	-	-	-	-	-
IOKFKOHM_03538	2.72e-209	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
IOKFKOHM_03539	4.11e-36	-	-	-	-	-	-	-	-
IOKFKOHM_03540	1.11e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
IOKFKOHM_03541	1.07e-05	-	-	-	-	-	-	-	-
IOKFKOHM_03542	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase A domain
IOKFKOHM_03544	0.0	-	-	-	L	-	-	-	Virulence-associated protein E
IOKFKOHM_03545	3.49e-29	-	-	-	S	-	-	-	VRR_NUC
IOKFKOHM_03546	4.56e-289	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
IOKFKOHM_03547	2.58e-65	-	-	-	-	-	-	-	-
IOKFKOHM_03552	7.74e-77	-	-	-	L	-	-	-	Terminase, small subunit
IOKFKOHM_03553	0.0	terL	-	-	S	-	-	-	Terminase
IOKFKOHM_03555	1.8e-214	-	-	-	S	-	-	-	portal protein
IOKFKOHM_03556	3.96e-94	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
IOKFKOHM_03557	1.03e-164	-	-	-	S	-	-	-	capsid protein
IOKFKOHM_03558	3.4e-15	-	-	-	-	-	-	-	-
IOKFKOHM_03560	2.01e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
IOKFKOHM_03561	8.3e-40	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IOKFKOHM_03563	2.55e-36	-	-	-	S	-	-	-	Phage tail tube protein
IOKFKOHM_03566	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
IOKFKOHM_03568	4.26e-134	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IOKFKOHM_03569	3.2e-316	-	-	-	-	-	-	-	-
IOKFKOHM_03570	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IOKFKOHM_03571	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
IOKFKOHM_03572	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IOKFKOHM_03573	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
IOKFKOHM_03574	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOKFKOHM_03575	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IOKFKOHM_03576	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
IOKFKOHM_03577	7.42e-162	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOKFKOHM_03578	1.82e-112	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IOKFKOHM_03579	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOKFKOHM_03580	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
IOKFKOHM_03581	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOKFKOHM_03582	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOKFKOHM_03583	8.65e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOKFKOHM_03584	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
IOKFKOHM_03585	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IOKFKOHM_03586	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOKFKOHM_03587	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IOKFKOHM_03588	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOKFKOHM_03589	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOKFKOHM_03590	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOKFKOHM_03591	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOKFKOHM_03592	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IOKFKOHM_03593	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOKFKOHM_03594	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOKFKOHM_03595	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
IOKFKOHM_03596	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOKFKOHM_03597	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOKFKOHM_03598	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOKFKOHM_03599	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOKFKOHM_03600	2.52e-237	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
IOKFKOHM_03601	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IOKFKOHM_03602	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOKFKOHM_03603	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IOKFKOHM_03604	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOKFKOHM_03605	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOKFKOHM_03606	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOKFKOHM_03607	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOKFKOHM_03608	6.89e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOKFKOHM_03609	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOKFKOHM_03610	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IOKFKOHM_03611	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOKFKOHM_03612	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOKFKOHM_03613	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOKFKOHM_03614	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOKFKOHM_03615	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOKFKOHM_03616	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOKFKOHM_03617	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOKFKOHM_03618	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOKFKOHM_03619	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOKFKOHM_03620	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IOKFKOHM_03621	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IOKFKOHM_03622	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOKFKOHM_03623	2.07e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOKFKOHM_03624	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IOKFKOHM_03625	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOKFKOHM_03626	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IOKFKOHM_03627	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOKFKOHM_03628	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOKFKOHM_03629	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOKFKOHM_03630	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IOKFKOHM_03631	1.24e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOKFKOHM_03632	1.28e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOKFKOHM_03633	3.23e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOKFKOHM_03634	6.15e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOKFKOHM_03635	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOKFKOHM_03636	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IOKFKOHM_03637	2.28e-143	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOKFKOHM_03638	4.81e-78	-	-	-	E	-	-	-	IrrE N-terminal-like domain
IOKFKOHM_03639	3.84e-70	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOKFKOHM_03640	1.99e-28	-	-	-	-	-	-	-	-
IOKFKOHM_03641	2.23e-26	-	-	-	-	-	-	-	-
IOKFKOHM_03643	1.64e-26	-	-	-	-	-	-	-	-
IOKFKOHM_03644	1.28e-105	-	-	-	-	-	-	-	-
IOKFKOHM_03645	1.03e-27	-	-	-	S	-	-	-	Uncharacterized protein YqaH
IOKFKOHM_03647	1.54e-119	-	-	-	S	-	-	-	DNA protection
IOKFKOHM_03648	5.65e-205	-	-	-	D	-	-	-	AAA domain
IOKFKOHM_03649	3.5e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
IOKFKOHM_03650	0.0	-	-	-	S	-	-	-	hydrolase activity
IOKFKOHM_03651	3.9e-85	-	-	-	-	-	-	-	-
IOKFKOHM_03652	1.82e-120	-	-	-	S	-	-	-	nuclease activity
IOKFKOHM_03653	2.39e-103	-	-	-	-	-	-	-	-
IOKFKOHM_03655	3.98e-25	-	-	-	S	-	-	-	YopX protein
IOKFKOHM_03657	2.62e-78	-	-	-	-	-	-	-	-
IOKFKOHM_03660	5e-36	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
IOKFKOHM_03662	3.75e-213	-	-	-	S	-	-	-	Phage Terminase
IOKFKOHM_03663	3.41e-139	-	-	-	S	-	-	-	Phage portal protein
IOKFKOHM_03664	9.76e-61	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
IOKFKOHM_03665	1.08e-113	-	-	-	S	-	-	-	Phage capsid family
IOKFKOHM_03666	7.25e-16	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IOKFKOHM_03668	7.41e-15	-	-	-	S	-	-	-	TIGRFAM phage protein, HK97 gp10 family
IOKFKOHM_03672	7.5e-169	-	-	-	D	-	-	-	phage tail tape measure protein
IOKFKOHM_03674	3.98e-126	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IOKFKOHM_03675	0.0	-	-	-	-	-	-	-	-
IOKFKOHM_03676	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
IOKFKOHM_03677	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
IOKFKOHM_03678	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
IOKFKOHM_03679	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IOKFKOHM_03680	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IOKFKOHM_03681	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
IOKFKOHM_03682	2.06e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
IOKFKOHM_03683	2.51e-13	-	-	-	-	-	-	-	-
IOKFKOHM_03685	3.28e-48	-	-	-	-	-	-	-	-
IOKFKOHM_03687	6.87e-179	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IOKFKOHM_03688	4.02e-72	-	-	-	S	-	-	-	Bacteriophage holin family
IOKFKOHM_03689	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
IOKFKOHM_03690	2.52e-36	-	-	-	-	-	-	-	-
IOKFKOHM_03691	8.94e-100	yqbJ	-	-	-	-	-	-	-
IOKFKOHM_03692	1.79e-112	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IOKFKOHM_03693	9.68e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
IOKFKOHM_03694	1.43e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
IOKFKOHM_03695	2.12e-60	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
IOKFKOHM_03696	9.21e-216	xkdG	-	-	S	-	-	-	Phage capsid family
IOKFKOHM_03697	5.46e-186	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
IOKFKOHM_03698	2.13e-149	-	-	-	-	-	-	-	-
IOKFKOHM_03699	1.73e-217	-	-	-	S	-	-	-	Phage Mu protein F like protein
IOKFKOHM_03700	0.0	yqbA	-	-	S	-	-	-	portal protein
IOKFKOHM_03701	0.0	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
IOKFKOHM_03702	2.02e-158	yqaS	-	-	L	-	-	-	DNA packaging
IOKFKOHM_03704	1.58e-105	yqaQ	-	-	L	-	-	-	Transposase
IOKFKOHM_03705	7.56e-214	-	-	-	-	-	-	-	-
IOKFKOHM_03706	2.49e-43	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
IOKFKOHM_03707	1.38e-97	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
IOKFKOHM_03709	4.9e-214	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
IOKFKOHM_03710	1.92e-158	yqaL	-	-	L	-	-	-	DnaD domain protein
IOKFKOHM_03711	9.07e-198	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
IOKFKOHM_03712	9.38e-229	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
IOKFKOHM_03716	1.27e-134	-	-	-	-	-	-	-	-
IOKFKOHM_03718	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOKFKOHM_03719	1.25e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
IOKFKOHM_03721	8.73e-132	yqaC	-	-	F	-	-	-	adenylate kinase activity
IOKFKOHM_03722	1.58e-122	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IOKFKOHM_03723	4.46e-79	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOKFKOHM_03724	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOKFKOHM_03725	1.14e-197	yybE	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_03726	7.09e-88	-	-	-	K	-	-	-	Glyoxalase bleomycin resistance protein dioxygenase
IOKFKOHM_03728	4.93e-266	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
IOKFKOHM_03729	3.2e-13	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOKFKOHM_03730	1.72e-221	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IOKFKOHM_03731	3.4e-49	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IOKFKOHM_03733	5.52e-37	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
IOKFKOHM_03734	1.1e-20	-	-	-	S	-	-	-	SMI1 / KNR4 family
IOKFKOHM_03735	5.24e-60	-	-	-	-	-	-	-	-
IOKFKOHM_03740	5.5e-37	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
IOKFKOHM_03741	1.89e-40	-	-	-	-	-	-	-	-
IOKFKOHM_03743	5.08e-26	xkdM	-	-	S	-	-	-	Phage tail tube protein
IOKFKOHM_03744	2.43e-14	-	-	-	-	-	-	-	-
IOKFKOHM_03747	7.44e-05	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
IOKFKOHM_03750	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOKFKOHM_03751	1.08e-268	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_03752	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
IOKFKOHM_03753	2.93e-297	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOKFKOHM_03754	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
IOKFKOHM_03755	8.49e-217	yrdR	-	-	EG	-	-	-	EamA-like transporter family
IOKFKOHM_03756	9.47e-202	-	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_03757	1.67e-251	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
IOKFKOHM_03758	9.21e-216	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
IOKFKOHM_03759	6.48e-288	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOKFKOHM_03760	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
IOKFKOHM_03761	1.88e-175	azlC	-	-	E	-	-	-	AzlC protein
IOKFKOHM_03762	4.82e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
IOKFKOHM_03763	7.91e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
IOKFKOHM_03764	3.11e-289	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOKFKOHM_03766	7.38e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
IOKFKOHM_03767	1.09e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
IOKFKOHM_03769	2.01e-118	yrdA	-	-	S	-	-	-	DinB family
IOKFKOHM_03770	1.48e-212	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
IOKFKOHM_03771	2.45e-245	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IOKFKOHM_03772	9.78e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOKFKOHM_03773	2.29e-160	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
IOKFKOHM_03775	4.22e-164	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IOKFKOHM_03776	2.5e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_03777	4.9e-239	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
IOKFKOHM_03778	3.87e-200	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IOKFKOHM_03779	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOKFKOHM_03780	1.69e-191	-	-	-	S	-	-	-	Alpha beta hydrolase
IOKFKOHM_03781	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
IOKFKOHM_03782	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
IOKFKOHM_03783	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
IOKFKOHM_03784	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
IOKFKOHM_03785	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
IOKFKOHM_03786	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IOKFKOHM_03787	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
IOKFKOHM_03788	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
IOKFKOHM_03789	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IOKFKOHM_03790	1.76e-39	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
IOKFKOHM_03791	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
IOKFKOHM_03792	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IOKFKOHM_03793	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOKFKOHM_03794	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IOKFKOHM_03795	7.98e-166	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IOKFKOHM_03796	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
IOKFKOHM_03797	4.41e-96	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOKFKOHM_03798	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
IOKFKOHM_03799	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IOKFKOHM_03800	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
IOKFKOHM_03801	5.9e-194	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
IOKFKOHM_03802	9.97e-114	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_03803	4.99e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
IOKFKOHM_03804	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
IOKFKOHM_03805	6.32e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
IOKFKOHM_03806	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IOKFKOHM_03807	9.22e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
IOKFKOHM_03808	1.18e-121	yrhH	-	-	Q	-	-	-	methyltransferase
IOKFKOHM_03809	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
IOKFKOHM_03811	1.13e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
IOKFKOHM_03812	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IOKFKOHM_03813	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IOKFKOHM_03814	6.05e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IOKFKOHM_03815	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
IOKFKOHM_03816	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IOKFKOHM_03817	9.59e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
IOKFKOHM_03818	1.62e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOKFKOHM_03819	1.4e-152	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
IOKFKOHM_03820	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
IOKFKOHM_03821	8.2e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
IOKFKOHM_03822	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
IOKFKOHM_03823	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOKFKOHM_03826	1.11e-112	-	-	-	S	-	-	-	Toxin SpoIISA, type II toxin-antitoxin system
IOKFKOHM_03827	2.4e-232	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IOKFKOHM_03831	2.47e-163	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IOKFKOHM_03832	9.16e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
IOKFKOHM_03833	4.44e-38	bhlA	-	-	S	-	-	-	BhlA holin family
IOKFKOHM_03836	3.77e-222	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IOKFKOHM_03837	7.42e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
IOKFKOHM_03838	2.3e-159	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
IOKFKOHM_03839	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IOKFKOHM_03840	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOKFKOHM_03841	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IOKFKOHM_03842	1.2e-116	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IOKFKOHM_03843	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOKFKOHM_03844	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IOKFKOHM_03845	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IOKFKOHM_03846	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
IOKFKOHM_03847	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOKFKOHM_03848	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOKFKOHM_03849	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOKFKOHM_03850	2.31e-194	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
IOKFKOHM_03851	6.3e-76	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
IOKFKOHM_03852	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
IOKFKOHM_03853	1.06e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IOKFKOHM_03854	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
IOKFKOHM_03855	1.09e-223	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOKFKOHM_03856	5.36e-148	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
IOKFKOHM_03857	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOKFKOHM_03858	8e-177	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
IOKFKOHM_03859	5.98e-202	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
IOKFKOHM_03860	1.53e-245	-	-	-	S	-	-	-	Ion transport 2 domain protein
IOKFKOHM_03861	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOKFKOHM_03862	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
IOKFKOHM_03863	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
IOKFKOHM_03864	1.09e-205	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
IOKFKOHM_03866	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
IOKFKOHM_03867	4.9e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IOKFKOHM_03868	7.65e-226	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
IOKFKOHM_03869	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
IOKFKOHM_03870	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IOKFKOHM_03871	6.13e-199	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOKFKOHM_03872	9.32e-225	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
IOKFKOHM_03873	2.63e-284	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IOKFKOHM_03874	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
IOKFKOHM_03875	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IOKFKOHM_03876	7.14e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_03877	4.27e-310	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
IOKFKOHM_03878	4.65e-281	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IOKFKOHM_03879	9.69e-164	yebC	-	-	M	-	-	-	Membrane
IOKFKOHM_03881	1.08e-119	yebE	-	-	S	-	-	-	UPF0316 protein
IOKFKOHM_03882	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
IOKFKOHM_03883	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOKFKOHM_03884	2.21e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOKFKOHM_03885	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOKFKOHM_03886	2.04e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IOKFKOHM_03887	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOKFKOHM_03888	1.91e-166	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOKFKOHM_03889	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOKFKOHM_03890	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOKFKOHM_03891	4.9e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IOKFKOHM_03892	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOKFKOHM_03893	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IOKFKOHM_03894	8.08e-298	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IOKFKOHM_03895	2.51e-94	-	-	-	K	-	-	-	helix_turn_helix ASNC type
IOKFKOHM_03896	1.23e-293	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
IOKFKOHM_03897	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
IOKFKOHM_03898	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
IOKFKOHM_03899	1.93e-243	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
IOKFKOHM_03900	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_03901	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
IOKFKOHM_03902	1.1e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IOKFKOHM_03903	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IOKFKOHM_03904	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOKFKOHM_03905	7.21e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
IOKFKOHM_03906	8.56e-251	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
IOKFKOHM_03907	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
IOKFKOHM_03908	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOKFKOHM_03909	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOKFKOHM_03910	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOKFKOHM_03911	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOKFKOHM_03912	2.96e-190	yerO	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_03913	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IOKFKOHM_03914	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IOKFKOHM_03915	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOKFKOHM_03916	4.15e-26	-	-	-	L	-	-	-	DNA binding domain protein, excisionase family
IOKFKOHM_03917	1.12e-129	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
IOKFKOHM_03918	8.8e-159	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
IOKFKOHM_03919	7.62e-269	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
IOKFKOHM_03920	0.0	-	-	-	L	-	-	-	LlaJI restriction endonuclease
IOKFKOHM_03921	2.79e-231	-	-	-	E	-	-	-	Zn peptidase
IOKFKOHM_03922	2.23e-191	-	-	-	E	-	-	-	Zn peptidase
IOKFKOHM_03923	4.54e-91	-	-	-	-	-	-	-	-
IOKFKOHM_03924	0.0	-	-	-	-	-	-	-	-
IOKFKOHM_03925	1.56e-214	-	-	-	-	-	-	-	-
IOKFKOHM_03926	6.41e-115	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOKFKOHM_03927	2.51e-05	-	-	-	-	-	-	-	-
IOKFKOHM_03928	4.44e-22	-	-	-	-	-	-	-	-
IOKFKOHM_03929	2.73e-198	-	-	-	S	-	-	-	Bacterial EndoU nuclease
IOKFKOHM_03931	1.14e-125	-	-	-	L	-	-	-	endonuclease activity
IOKFKOHM_03932	1.65e-209	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
IOKFKOHM_03933	1.73e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IOKFKOHM_03935	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
IOKFKOHM_03937	2e-129	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_03938	1.6e-103	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
IOKFKOHM_03939	1.43e-194	yesF	-	-	GM	-	-	-	NAD(P)H-binding
IOKFKOHM_03940	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
IOKFKOHM_03941	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
IOKFKOHM_03942	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
IOKFKOHM_03943	4.15e-131	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IOKFKOHM_03945	4.6e-131	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
IOKFKOHM_03946	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOKFKOHM_03947	1.39e-257	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
IOKFKOHM_03948	8.33e-314	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOKFKOHM_03949	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOKFKOHM_03950	8.84e-211	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOKFKOHM_03951	4.63e-253	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
IOKFKOHM_03952	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
IOKFKOHM_03953	9.4e-167	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOKFKOHM_03954	1.25e-163	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
IOKFKOHM_03955	3.86e-143	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOKFKOHM_03956	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IOKFKOHM_03957	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IOKFKOHM_03958	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOKFKOHM_03959	3.02e-283	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
IOKFKOHM_03960	1.05e-188	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
IOKFKOHM_03961	0.0	yetA	-	-	-	-	-	-	-
IOKFKOHM_03962	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOKFKOHM_03963	1.18e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IOKFKOHM_03964	2.62e-207	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOKFKOHM_03965	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IOKFKOHM_03966	1.81e-157	yetF	-	-	S	-	-	-	membrane
IOKFKOHM_03967	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
IOKFKOHM_03968	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOKFKOHM_03969	7.44e-132	-	-	-	-	-	-	-	-
IOKFKOHM_03970	1.66e-276	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IOKFKOHM_03971	1.19e-135	-	-	-	S	-	-	-	Phage tail protein
IOKFKOHM_03972	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
IOKFKOHM_03975	3.95e-102	-	-	-	S	-	-	-	Phage tail tube protein
IOKFKOHM_03977	4.86e-66	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IOKFKOHM_03978	2.13e-51	-	-	-	S	-	-	-	Phage head-tail joining protein
IOKFKOHM_03979	1.4e-50	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IOKFKOHM_03980	5.99e-34	-	-	-	-	-	-	-	-
IOKFKOHM_03981	4.3e-266	-	-	-	S	-	-	-	capsid protein
IOKFKOHM_03982	1.51e-151	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
IOKFKOHM_03983	9.21e-304	-	-	-	S	-	-	-	Phage portal protein
IOKFKOHM_03985	0.0	-	-	-	S	-	-	-	Terminase
IOKFKOHM_03986	2.11e-101	-	-	-	L	-	-	-	phage terminase small subunit
IOKFKOHM_03987	3.98e-65	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
IOKFKOHM_03992	1.71e-77	-	-	-	L	-	-	-	Phage integrase family
IOKFKOHM_03993	7.59e-68	-	-	-	M	-	-	-	ArpU family transcriptional regulator
IOKFKOHM_03997	1.54e-56	-	-	-	S	-	-	-	dUTPase
IOKFKOHM_03999	2.23e-85	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
IOKFKOHM_04003	2.78e-08	-	-	-	-	-	-	-	-
IOKFKOHM_04006	4.86e-10	-	-	-	-	-	-	-	-
IOKFKOHM_04008	2.01e-64	-	-	-	L	ko:K02315,ko:K11144	-	ko00000,ko03032	DNA replication protein
IOKFKOHM_04009	6.22e-91	-	-	-	L	-	-	-	dnaD_dom DnaD domain protein
IOKFKOHM_04012	7.13e-09	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
IOKFKOHM_04013	1.57e-37	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOKFKOHM_04015	2.31e-08	-	-	-	-	-	-	-	-
IOKFKOHM_04016	7.76e-76	-	-	-	L	-	-	-	Arm DNA-binding domain
IOKFKOHM_04017	5.91e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IOKFKOHM_04018	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
IOKFKOHM_04019	6.3e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IOKFKOHM_04020	6.92e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
IOKFKOHM_04021	1.45e-239	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOKFKOHM_04022	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IOKFKOHM_04023	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOKFKOHM_04024	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IOKFKOHM_04025	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOKFKOHM_04026	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
IOKFKOHM_04027	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IOKFKOHM_04028	1.28e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOKFKOHM_04029	3.24e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOKFKOHM_04030	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOKFKOHM_04031	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
IOKFKOHM_04032	8.4e-42	yrzR	-	-	-	-	-	-	-
IOKFKOHM_04033	5.87e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_04034	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOKFKOHM_04035	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
IOKFKOHM_04036	4.83e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOKFKOHM_04037	1.21e-268	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IOKFKOHM_04038	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
IOKFKOHM_04039	2.44e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IOKFKOHM_04040	2.68e-175	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IOKFKOHM_04041	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IOKFKOHM_04042	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IOKFKOHM_04044	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
IOKFKOHM_04045	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOKFKOHM_04046	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOKFKOHM_04047	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOKFKOHM_04048	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IOKFKOHM_04049	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IOKFKOHM_04050	5.35e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IOKFKOHM_04051	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IOKFKOHM_04052	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
IOKFKOHM_04053	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOKFKOHM_04054	8.64e-145	yrbG	-	-	S	-	-	-	membrane
IOKFKOHM_04055	2.16e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
IOKFKOHM_04056	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
IOKFKOHM_04057	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOKFKOHM_04058	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IOKFKOHM_04059	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
IOKFKOHM_04060	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOKFKOHM_04061	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOKFKOHM_04062	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
IOKFKOHM_04063	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
IOKFKOHM_04064	1.67e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IOKFKOHM_04065	3.17e-150	yrzF	-	-	T	-	-	-	serine threonine protein kinase
IOKFKOHM_04067	1.47e-66	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
IOKFKOHM_04068	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
IOKFKOHM_04069	2.37e-162	yebC	-	-	K	-	-	-	transcriptional regulatory protein
IOKFKOHM_04070	1.47e-69	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOKFKOHM_04071	4.02e-216	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
IOKFKOHM_04072	7.94e-273	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IOKFKOHM_04073	4.34e-203	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
IOKFKOHM_04074	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
IOKFKOHM_04075	6.49e-288	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IOKFKOHM_04076	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
IOKFKOHM_04077	2.89e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IOKFKOHM_04078	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IOKFKOHM_04079	5.59e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOKFKOHM_04080	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
IOKFKOHM_04081	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IOKFKOHM_04082	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
IOKFKOHM_04083	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IOKFKOHM_04084	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
IOKFKOHM_04085	3.03e-186	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IOKFKOHM_04086	6.84e-185	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IOKFKOHM_04087	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IOKFKOHM_04088	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
IOKFKOHM_04089	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IOKFKOHM_04090	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
IOKFKOHM_04106	2.73e-28	xhlB	-	-	S	-	-	-	SPP1 phage holin
IOKFKOHM_04107	1.27e-43	-	-	-	K	-	-	-	sigma factor activity
IOKFKOHM_04108	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
IOKFKOHM_04109	4.33e-207	ybfH	-	-	EG	-	-	-	EamA-like transporter family
IOKFKOHM_04110	3.74e-284	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOKFKOHM_04111	4.07e-216	ybfA	-	-	K	-	-	-	FR47-like protein
IOKFKOHM_04112	5.07e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IOKFKOHM_04113	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
IOKFKOHM_04114	2.85e-210	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
IOKFKOHM_04115	0.0	ybeC	-	-	E	-	-	-	amino acid
IOKFKOHM_04116	1.11e-54	ybyB	-	-	-	-	-	-	-
IOKFKOHM_04117	2.67e-314	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
IOKFKOHM_04118	5.85e-29	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
IOKFKOHM_04119	2.18e-132	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
IOKFKOHM_04120	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
IOKFKOHM_04121	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
IOKFKOHM_04122	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOKFKOHM_04123	1.89e-275	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
IOKFKOHM_04124	1.05e-192	ybdN	-	-	-	-	-	-	-
IOKFKOHM_04125	4.44e-175	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOKFKOHM_04127	9.98e-75	-	-	-	-	-	-	-	-
IOKFKOHM_04128	1.09e-256	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IOKFKOHM_04129	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
IOKFKOHM_04131	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IOKFKOHM_04132	5.59e-64	-	-	-	-	-	-	-	-
IOKFKOHM_04133	1.34e-120	ybcF	-	-	P	-	-	-	carbonic anhydrase
IOKFKOHM_04134	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
IOKFKOHM_04135	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IOKFKOHM_04136	3.69e-129	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOKFKOHM_04137	6.2e-155	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
IOKFKOHM_04138	2.67e-220	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IOKFKOHM_04139	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOKFKOHM_04140	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOKFKOHM_04141	3.55e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_04142	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOKFKOHM_04143	6.45e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IOKFKOHM_04144	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOKFKOHM_04150	4.19e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
IOKFKOHM_04151	3.13e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
IOKFKOHM_04152	1.92e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOKFKOHM_04153	5.43e-194	ybbH	-	-	K	-	-	-	transcriptional
IOKFKOHM_04154	2.97e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOKFKOHM_04155	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
IOKFKOHM_04156	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
IOKFKOHM_04157	2.33e-302	ybbC	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_04158	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
IOKFKOHM_04159	2.08e-215	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
IOKFKOHM_04160	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_04161	1.43e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOKFKOHM_04162	5.24e-180	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
IOKFKOHM_04163	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
IOKFKOHM_04165	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IOKFKOHM_04166	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
IOKFKOHM_04167	8.66e-227	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
IOKFKOHM_04168	0.0	yhaN	-	-	L	-	-	-	AAA domain
IOKFKOHM_04169	2.71e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
IOKFKOHM_04170	8.51e-271	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
IOKFKOHM_04171	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOKFKOHM_04172	2.29e-36	-	-	-	S	-	-	-	YhzD-like protein
IOKFKOHM_04173	1.79e-169	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
IOKFKOHM_04175	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IOKFKOHM_04176	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
IOKFKOHM_04177	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
IOKFKOHM_04178	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IOKFKOHM_04179	1.29e-261	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IOKFKOHM_04180	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IOKFKOHM_04181	4.16e-259	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
IOKFKOHM_04182	2.77e-275	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IOKFKOHM_04183	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IOKFKOHM_04184	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
IOKFKOHM_04185	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IOKFKOHM_04186	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
IOKFKOHM_04187	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOKFKOHM_04188	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOKFKOHM_04189	1.53e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
IOKFKOHM_04190	1.2e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IOKFKOHM_04191	9.44e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IOKFKOHM_04192	1.63e-199	nodB1	-	-	G	-	-	-	deacetylase
IOKFKOHM_04193	4.85e-179	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IOKFKOHM_04194	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
IOKFKOHM_04195	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
IOKFKOHM_04196	1.23e-170	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IOKFKOHM_04197	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOKFKOHM_04198	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOKFKOHM_04199	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOKFKOHM_04200	5.1e-284	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IOKFKOHM_04201	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
IOKFKOHM_04202	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOKFKOHM_04203	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOKFKOHM_04204	2.51e-13	-	-	-	-	-	-	-	-
IOKFKOHM_04207	1.66e-22	-	-	-	K	-	-	-	Helix-turn-helix domain
IOKFKOHM_04209	3.97e-156	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IOKFKOHM_04210	6.15e-75	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
IOKFKOHM_04211	2.14e-232	yaaC	-	-	S	-	-	-	YaaC-like Protein
IOKFKOHM_04212	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IOKFKOHM_04213	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IOKFKOHM_04214	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IOKFKOHM_04215	1.93e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IOKFKOHM_04216	1.09e-292	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOKFKOHM_04218	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
IOKFKOHM_04219	2.34e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
IOKFKOHM_04220	2.99e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
IOKFKOHM_04221	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
IOKFKOHM_04222	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOKFKOHM_04223	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOKFKOHM_04224	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOKFKOHM_04225	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOKFKOHM_04226	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IOKFKOHM_04227	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
IOKFKOHM_04228	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
IOKFKOHM_04229	2.7e-132	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IOKFKOHM_04230	8.37e-259	yaaN	-	-	P	-	-	-	Belongs to the TelA family
IOKFKOHM_04231	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
IOKFKOHM_04232	1.63e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOKFKOHM_04233	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_04234	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
IOKFKOHM_04235	3.78e-229	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOKFKOHM_04236	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
IOKFKOHM_04237	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IOKFKOHM_04238	3.28e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
IOKFKOHM_04239	2.84e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
IOKFKOHM_04240	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOKFKOHM_04241	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
IOKFKOHM_04242	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOKFKOHM_04243	3.41e-183	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
IOKFKOHM_04244	7.77e-283	yabE	-	-	T	-	-	-	protein conserved in bacteria
IOKFKOHM_04245	2.46e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOKFKOHM_04246	5.04e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOKFKOHM_04247	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
IOKFKOHM_04248	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
IOKFKOHM_04249	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
IOKFKOHM_04250	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOKFKOHM_04251	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IOKFKOHM_04252	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
IOKFKOHM_04253	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IOKFKOHM_04254	4.27e-308	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOKFKOHM_04255	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOKFKOHM_04256	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IOKFKOHM_04257	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOKFKOHM_04258	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
IOKFKOHM_04259	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOKFKOHM_04260	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
IOKFKOHM_04261	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOKFKOHM_04262	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IOKFKOHM_04263	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IOKFKOHM_04264	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
IOKFKOHM_04265	1.05e-137	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
IOKFKOHM_04266	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IOKFKOHM_04267	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IOKFKOHM_04270	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
IOKFKOHM_04271	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IOKFKOHM_04272	1.2e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IOKFKOHM_04273	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOKFKOHM_04274	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
IOKFKOHM_04275	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOKFKOHM_04276	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IOKFKOHM_04277	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOKFKOHM_04278	2.23e-194	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
IOKFKOHM_04279	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IOKFKOHM_04280	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOKFKOHM_04281	2.44e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
IOKFKOHM_04282	1.04e-212	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
IOKFKOHM_04283	3.32e-205	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IOKFKOHM_04284	7.67e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOKFKOHM_04285	5.33e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IOKFKOHM_04286	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
IOKFKOHM_04287	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOKFKOHM_04288	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IOKFKOHM_04290	1.17e-283	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOKFKOHM_04291	6.83e-96	-	-	-	L	-	-	-	Integrase core domain
IOKFKOHM_04294	8.28e-219	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain