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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PELLHMED_00001	1.3e-307	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PELLHMED_00002	1.46e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PELLHMED_00003	6.15e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PELLHMED_00004	3.1e-269	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PELLHMED_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PELLHMED_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PELLHMED_00007	9.55e-66	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PELLHMED_00008	8.43e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PELLHMED_00009	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PELLHMED_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PELLHMED_00011	6.96e-100	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PELLHMED_00012	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PELLHMED_00013	1e-220	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
PELLHMED_00014	1.38e-225	degV1	-	-	S	-	-	-	DegV family
PELLHMED_00015	1.09e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PELLHMED_00016	1.38e-33	-	-	-	S	-	-	-	CsbD-like
PELLHMED_00017	1.47e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
PELLHMED_00018	1.25e-303	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
PELLHMED_00020	7.47e-133	cadD	-	-	P	-	-	-	Cadmium resistance transporter
PELLHMED_00021	2.41e-77	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PELLHMED_00022	2.93e-235	-	-	-	-	-	-	-	-
PELLHMED_00023	1.08e-71	-	-	-	-	-	-	-	-
PELLHMED_00024	7.23e-264	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PELLHMED_00025	4.15e-120	-	-	-	-	-	-	-	-
PELLHMED_00026	1.16e-234	-	-	-	EP	-	-	-	Plasmid replication protein
PELLHMED_00027	1.45e-42	-	-	-	-	-	-	-	-
PELLHMED_00028	8.39e-299	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PELLHMED_00029	4.37e-43	-	-	-	-	-	-	-	-
PELLHMED_00030	4.41e-92	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
PELLHMED_00031	1.63e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
PELLHMED_00034	2.01e-205	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
PELLHMED_00035	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PELLHMED_00036	1.5e-295	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
PELLHMED_00037	1.4e-196	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PELLHMED_00038	2.37e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
PELLHMED_00039	6.12e-112	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
PELLHMED_00040	9.95e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
PELLHMED_00041	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
PELLHMED_00042	2e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
PELLHMED_00043	2.37e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PELLHMED_00044	9.67e-22	-	-	-	-	-	-	-	-
PELLHMED_00045	2.79e-313	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PELLHMED_00046	6.35e-69	-	-	-	-	-	-	-	-
PELLHMED_00047	8.29e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_00048	3.51e-170	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PELLHMED_00049	3.82e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PELLHMED_00050	1.29e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PELLHMED_00051	0.0	fusA1	-	-	J	-	-	-	elongation factor G
PELLHMED_00052	1.99e-195	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PELLHMED_00053	9.66e-41	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
PELLHMED_00054	1.63e-172	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
PELLHMED_00055	8.28e-15	-	-	-	S	-	-	-	interspecies interaction between organisms
PELLHMED_00056	5.27e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PELLHMED_00057	3.08e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PELLHMED_00058	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
PELLHMED_00059	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PELLHMED_00060	3.12e-273	pbpX1	-	-	V	-	-	-	Beta-lactamase
PELLHMED_00061	6.19e-94	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PELLHMED_00063	3.73e-65	-	-	-	K	-	-	-	LysR substrate binding domain
PELLHMED_00064	4.38e-74	-	-	-	S	-	-	-	FMN_bind
PELLHMED_00065	1.87e-292	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PELLHMED_00066	3.17e-149	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
PELLHMED_00067	2.5e-51	-	-	-	S	-	-	-	Cytochrome B5
PELLHMED_00068	2.27e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
PELLHMED_00069	1.34e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
PELLHMED_00070	1.07e-238	-	-	-	M	-	-	-	Glycosyl transferase family 8
PELLHMED_00071	6.45e-204	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
PELLHMED_00072	1.11e-191	-	-	-	I	-	-	-	Acyl-transferase
PELLHMED_00073	8.36e-102	-	-	-	-	-	-	-	-
PELLHMED_00074	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
PELLHMED_00075	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PELLHMED_00076	0.0	-	-	-	L	-	-	-	Transposase
PELLHMED_00079	9.77e-170	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PELLHMED_00080	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PELLHMED_00081	0.0	yycH	-	-	S	-	-	-	YycH protein
PELLHMED_00082	3.54e-190	yycI	-	-	S	-	-	-	YycH protein
PELLHMED_00083	9.1e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PELLHMED_00084	1.63e-258	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PELLHMED_00085	2.48e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PELLHMED_00086	1.51e-194	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PELLHMED_00088	0.0	-	-	-	S	-	-	-	CAAX protease self-immunity
PELLHMED_00089	1.98e-26	-	-	-	-	-	-	-	-
PELLHMED_00090	1.09e-157	-	-	-	-	-	-	-	-
PELLHMED_00091	8e-226	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PELLHMED_00092	6.92e-130	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PELLHMED_00093	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PELLHMED_00094	2.11e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PELLHMED_00095	9.9e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PELLHMED_00096	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PELLHMED_00097	3.36e-249	ysdE	-	-	P	-	-	-	Citrate transporter
PELLHMED_00098	7.83e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PELLHMED_00099	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
PELLHMED_00100	9.69e-25	-	-	-	-	-	-	-	-
PELLHMED_00101	2.14e-197	-	-	-	-	-	-	-	-
PELLHMED_00103	1.08e-288	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
PELLHMED_00104	2.11e-271	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
PELLHMED_00105	1.07e-157	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PELLHMED_00106	2.73e-206	-	-	-	L	-	-	-	HNH nucleases
PELLHMED_00107	1.63e-233	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
PELLHMED_00108	2.21e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PELLHMED_00109	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PELLHMED_00110	3.08e-159	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PELLHMED_00111	2.29e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PELLHMED_00112	9.33e-180	terC	-	-	P	-	-	-	Integral membrane protein TerC family
PELLHMED_00113	2.57e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
PELLHMED_00114	9.36e-111	-	-	-	-	-	-	-	-
PELLHMED_00115	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PELLHMED_00116	1.45e-231	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PELLHMED_00117	2.82e-183	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PELLHMED_00118	5.06e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PELLHMED_00119	2.63e-204	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PELLHMED_00120	7.52e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PELLHMED_00121	1.02e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PELLHMED_00122	1.33e-75	-	-	-	-	-	-	-	-
PELLHMED_00123	0.0	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PELLHMED_00124	2.83e-62	-	-	-	-	-	-	-	-
PELLHMED_00125	5.31e-58	-	3.6.4.12	-	-	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	-
PELLHMED_00126	1.3e-99	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
PELLHMED_00127	1.51e-234	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PELLHMED_00128	1.19e-160	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PELLHMED_00129	2.93e-173	-	-	-	-	-	-	-	-
PELLHMED_00130	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PELLHMED_00131	7.42e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PELLHMED_00132	1.96e-293	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PELLHMED_00133	7.25e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PELLHMED_00134	1.49e-136	-	-	-	-	-	-	-	-
PELLHMED_00135	9.78e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PELLHMED_00136	1.71e-170	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PELLHMED_00137	7.56e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PELLHMED_00138	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
PELLHMED_00139	8.53e-292	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PELLHMED_00140	2.9e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
PELLHMED_00141	1.74e-112	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PELLHMED_00142	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PELLHMED_00143	3.95e-113	usp5	-	-	T	-	-	-	universal stress protein
PELLHMED_00144	7.56e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
PELLHMED_00145	4.46e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PELLHMED_00146	2.84e-171	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PELLHMED_00147	6.38e-191	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PELLHMED_00148	7.66e-141	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PELLHMED_00149	3.65e-109	-	-	-	-	-	-	-	-
PELLHMED_00150	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PELLHMED_00151	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PELLHMED_00152	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PELLHMED_00153	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PELLHMED_00154	1.29e-178	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PELLHMED_00155	1.6e-127	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PELLHMED_00156	4.3e-297	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
PELLHMED_00157	1.88e-292	yttB	-	-	EGP	-	-	-	Major Facilitator
PELLHMED_00158	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PELLHMED_00159	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PELLHMED_00160	6.3e-91	-	-	-	-	-	-	-	-
PELLHMED_00161	2.15e-21	-	-	-	-	-	-	-	-
PELLHMED_00162	3.76e-289	-	-	-	S	-	-	-	SLAP domain
PELLHMED_00163	4.97e-81	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
PELLHMED_00164	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
PELLHMED_00165	2.97e-234	-	-	-	-	-	-	-	-
PELLHMED_00166	8.52e-304	-	-	-	S	-	-	-	SLAP domain
PELLHMED_00167	2.53e-283	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PELLHMED_00168	7.59e-269	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
PELLHMED_00169	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PELLHMED_00170	6.61e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PELLHMED_00171	4.62e-181	-	-	-	-	-	-	-	-
PELLHMED_00172	2.12e-176	-	-	-	-	-	-	-	-
PELLHMED_00173	1.84e-170	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PELLHMED_00174	8.51e-143	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PELLHMED_00175	1.96e-132	-	-	-	G	-	-	-	Aldose 1-epimerase
PELLHMED_00176	1.34e-259	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PELLHMED_00177	2.73e-146	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PELLHMED_00178	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
PELLHMED_00179	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
PELLHMED_00180	6.28e-310	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PELLHMED_00181	1.02e-74	-	-	-	-	-	-	-	-
PELLHMED_00183	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PELLHMED_00184	1.16e-162	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PELLHMED_00185	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PELLHMED_00186	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PELLHMED_00187	8.86e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PELLHMED_00188	5.46e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PELLHMED_00189	1.92e-240	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PELLHMED_00190	1.9e-256	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PELLHMED_00191	1.87e-221	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PELLHMED_00192	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PELLHMED_00193	1.5e-96	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PELLHMED_00194	6.92e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PELLHMED_00195	1.09e-148	-	-	-	-	-	-	-	-
PELLHMED_00197	1.21e-146	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
PELLHMED_00198	2.35e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PELLHMED_00199	2.69e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
PELLHMED_00200	1.25e-142	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PELLHMED_00201	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PELLHMED_00202	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PELLHMED_00203	2.33e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PELLHMED_00204	1.63e-124	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PELLHMED_00205	4.9e-207	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PELLHMED_00206	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PELLHMED_00207	4.31e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PELLHMED_00208	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PELLHMED_00209	1.4e-116	-	-	-	S	-	-	-	SLAP domain
PELLHMED_00210	4.55e-117	-	-	-	S	-	-	-	SLAP domain
PELLHMED_00211	1.48e-114	-	-	-	-	-	-	-	-
PELLHMED_00212	0.0	-	-	-	S	-	-	-	SLAP domain
PELLHMED_00213	6.58e-227	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PELLHMED_00214	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PELLHMED_00215	3.82e-167	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PELLHMED_00216	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PELLHMED_00217	4.58e-216	-	-	-	GK	-	-	-	ROK family
PELLHMED_00218	4.88e-59	-	-	-	-	-	-	-	-
PELLHMED_00219	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PELLHMED_00220	4.39e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PELLHMED_00221	1.11e-96	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PELLHMED_00222	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PELLHMED_00223	6.32e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PELLHMED_00224	4.42e-142	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PELLHMED_00225	1.59e-205	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PELLHMED_00226	7.87e-207	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
PELLHMED_00227	1.87e-137	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PELLHMED_00228	1.21e-285	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PELLHMED_00229	5.8e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PELLHMED_00230	1.04e-173	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
PELLHMED_00231	3.77e-220	-	-	-	K	-	-	-	Helix-turn-helix
PELLHMED_00232	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PELLHMED_00233	7.77e-199	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PELLHMED_00234	3.12e-191	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PELLHMED_00235	1.03e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
PELLHMED_00236	1.16e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PELLHMED_00237	7.88e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PELLHMED_00238	9.09e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
PELLHMED_00239	2.07e-117	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
PELLHMED_00240	2.89e-44	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
PELLHMED_00241	5.49e-42	-	-	-	-	-	-	-	-
PELLHMED_00242	3.18e-106	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PELLHMED_00243	6.74e-39	-	-	-	K	ko:K12410	-	ko00000,ko01000	NAD+ binding
PELLHMED_00244	4.62e-13	-	-	-	P	-	-	-	Voltage gated chloride channel
PELLHMED_00245	7.47e-126	-	-	-	-	-	-	-	-
PELLHMED_00246	8.2e-68	-	-	-	-	-	-	-	-
PELLHMED_00247	4.88e-59	-	-	-	-	-	-	-	-
PELLHMED_00248	9.39e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PELLHMED_00249	0.0	-	-	-	E	-	-	-	amino acid
PELLHMED_00250	9.8e-204	supH	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PELLHMED_00251	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
PELLHMED_00252	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PELLHMED_00253	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PELLHMED_00254	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PELLHMED_00255	3.27e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PELLHMED_00256	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PELLHMED_00257	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
PELLHMED_00258	1.98e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PELLHMED_00259	6.58e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PELLHMED_00260	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PELLHMED_00261	1.79e-46	yabO	-	-	J	-	-	-	S4 domain protein
PELLHMED_00262	1.03e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PELLHMED_00263	3.95e-82	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
PELLHMED_00264	5.11e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PELLHMED_00265	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PELLHMED_00266	6.77e-215	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PELLHMED_00267	3.5e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PELLHMED_00268	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PELLHMED_00272	1.16e-107	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PELLHMED_00273	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PELLHMED_00274	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PELLHMED_00275	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PELLHMED_00276	6.6e-159	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
PELLHMED_00277	2.09e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PELLHMED_00278	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PELLHMED_00279	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PELLHMED_00280	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PELLHMED_00281	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PELLHMED_00282	1.91e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PELLHMED_00283	3.57e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PELLHMED_00284	9.85e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PELLHMED_00285	1.34e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PELLHMED_00286	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PELLHMED_00287	7.15e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PELLHMED_00288	9.64e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PELLHMED_00289	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PELLHMED_00290	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PELLHMED_00291	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PELLHMED_00292	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PELLHMED_00293	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PELLHMED_00294	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PELLHMED_00295	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PELLHMED_00296	2.5e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PELLHMED_00297	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PELLHMED_00298	5.3e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PELLHMED_00299	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PELLHMED_00300	2.45e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PELLHMED_00301	3.59e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PELLHMED_00302	1.29e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PELLHMED_00303	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PELLHMED_00304	4.63e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PELLHMED_00305	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PELLHMED_00306	3.95e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PELLHMED_00307	2.55e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PELLHMED_00308	1.57e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PELLHMED_00309	4.16e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PELLHMED_00310	4.04e-206	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PELLHMED_00311	1.74e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PELLHMED_00312	4.17e-192	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PELLHMED_00313	1.6e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PELLHMED_00314	8.28e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PELLHMED_00315	7.71e-255	-	-	-	L	-	-	-	Phage integrase family
PELLHMED_00316	4.24e-37	-	-	-	-	-	-	-	-
PELLHMED_00317	1.31e-270	-	-	-	EP	-	-	-	Plasmid replication protein
PELLHMED_00318	1.77e-61	-	-	-	-	-	-	-	-
PELLHMED_00319	2.52e-264	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PELLHMED_00320	1.48e-69	-	-	-	-	-	-	-	-
PELLHMED_00322	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
PELLHMED_00323	1.53e-85	-	-	-	S	-	-	-	YjcQ protein
PELLHMED_00325	5.27e-16	-	-	-	-	-	-	-	-
PELLHMED_00326	3.63e-141	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PELLHMED_00327	4.67e-154	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PELLHMED_00328	8.09e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PELLHMED_00329	6.91e-164	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PELLHMED_00330	5.3e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PELLHMED_00331	1.14e-27	-	-	-	-	-	-	-	-
PELLHMED_00332	1.27e-104	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PELLHMED_00333	9.84e-236	-	-	-	S	-	-	-	AAA domain
PELLHMED_00334	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PELLHMED_00335	9.95e-70	-	-	-	-	-	-	-	-
PELLHMED_00336	1.82e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PELLHMED_00337	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PELLHMED_00338	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PELLHMED_00339	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PELLHMED_00340	6.01e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PELLHMED_00341	4.31e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PELLHMED_00342	2.91e-121	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
PELLHMED_00343	2.41e-45	-	-	-	-	-	-	-	-
PELLHMED_00344	6.48e-148	-	-	-	-	-	-	-	-
PELLHMED_00345	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PELLHMED_00346	1.22e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PELLHMED_00347	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PELLHMED_00348	1.72e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PELLHMED_00349	3.66e-132	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PELLHMED_00350	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PELLHMED_00351	1.5e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PELLHMED_00352	2.83e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PELLHMED_00353	1.8e-223	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PELLHMED_00354	4.47e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PELLHMED_00355	4.47e-186	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PELLHMED_00356	5.67e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PELLHMED_00357	1.74e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PELLHMED_00358	3.62e-268	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PELLHMED_00359	1.86e-38	-	-	-	-	-	-	-	-
PELLHMED_00360	2.15e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PELLHMED_00361	9.31e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PELLHMED_00362	3.83e-167	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
PELLHMED_00363	1.25e-147	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PELLHMED_00364	4.9e-33	-	-	-	-	-	-	-	-
PELLHMED_00365	9.21e-120	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PELLHMED_00366	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PELLHMED_00367	1.71e-287	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PELLHMED_00368	2.2e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PELLHMED_00369	4.56e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PELLHMED_00370	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PELLHMED_00371	1.69e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PELLHMED_00372	1.85e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PELLHMED_00373	5.91e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PELLHMED_00374	2.65e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PELLHMED_00375	9.46e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PELLHMED_00376	1.29e-182	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PELLHMED_00377	6.76e-114	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PELLHMED_00378	8.02e-172	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PELLHMED_00379	1.49e-138	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PELLHMED_00380	5.62e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PELLHMED_00381	9.05e-170	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PELLHMED_00382	7.2e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PELLHMED_00383	4.46e-165	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
PELLHMED_00384	1.38e-298	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PELLHMED_00385	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PELLHMED_00386	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PELLHMED_00387	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PELLHMED_00388	1.24e-145	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PELLHMED_00389	6.41e-236	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PELLHMED_00390	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PELLHMED_00391	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PELLHMED_00392	4.92e-107	-	-	-	-	-	-	-	-
PELLHMED_00393	1.33e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
PELLHMED_00394	2.29e-175	-	-	-	S	-	-	-	membrane
PELLHMED_00395	2.22e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PELLHMED_00396	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PELLHMED_00397	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PELLHMED_00398	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PELLHMED_00399	2.35e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PELLHMED_00400	1.61e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PELLHMED_00401	2.41e-83	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PELLHMED_00402	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PELLHMED_00403	1.32e-255	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PELLHMED_00404	9.43e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PELLHMED_00405	8.26e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PELLHMED_00406	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PELLHMED_00407	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PELLHMED_00408	3.27e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PELLHMED_00409	2.03e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PELLHMED_00410	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PELLHMED_00411	1.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PELLHMED_00412	1.46e-70	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PELLHMED_00413	2.57e-91	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PELLHMED_00414	1.33e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PELLHMED_00415	1.42e-143	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PELLHMED_00416	3.18e-165	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PELLHMED_00417	2.09e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PELLHMED_00418	1.37e-74	-	-	-	-	-	-	-	-
PELLHMED_00419	4.1e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PELLHMED_00420	4.5e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PELLHMED_00421	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PELLHMED_00422	2.5e-74	-	-	-	-	-	-	-	-
PELLHMED_00423	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PELLHMED_00424	6.99e-134	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PELLHMED_00425	1.9e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PELLHMED_00426	3.19e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PELLHMED_00427	1.45e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PELLHMED_00428	4.65e-193	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PELLHMED_00447	1.98e-96	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PELLHMED_00448	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PELLHMED_00449	3.83e-61	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PELLHMED_00461	2.24e-284	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
PELLHMED_00462	1.5e-255	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PELLHMED_00463	5.18e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PELLHMED_00464	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PELLHMED_00465	5.29e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PELLHMED_00466	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PELLHMED_00467	1.99e-99	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PELLHMED_00469	1.36e-241	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PELLHMED_00470	1.67e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PELLHMED_00471	1.18e-225	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PELLHMED_00472	2.86e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
PELLHMED_00473	7.93e-206	-	-	-	K	-	-	-	Transcriptional regulator
PELLHMED_00474	3.62e-89	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PELLHMED_00475	2.27e-315	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PELLHMED_00476	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PELLHMED_00477	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PELLHMED_00478	1.47e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PELLHMED_00479	1.63e-175	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PELLHMED_00480	8.15e-94	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
PELLHMED_00481	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
PELLHMED_00482	0.0	-	-	-	S	-	-	-	TerB-C domain
PELLHMED_00483	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
PELLHMED_00484	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
PELLHMED_00485	4.47e-81	-	-	-	-	-	-	-	-
PELLHMED_00486	1.14e-294	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PELLHMED_00487	8.42e-187	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PELLHMED_00489	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
PELLHMED_00490	0.0	-	-	-	S	-	-	-	AAA ATPase domain
PELLHMED_00491	1.41e-208	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
PELLHMED_00492	8.37e-161	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
PELLHMED_00494	8.66e-76	-	-	-	-	-	-	-	-
PELLHMED_00495	2.66e-270	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PELLHMED_00497	3.69e-244	-	-	-	EP	-	-	-	Plasmid replication protein
PELLHMED_00498	6.89e-06	-	-	-	-	-	-	-	-
PELLHMED_00499	2.79e-296	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PELLHMED_00500	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PELLHMED_00501	3.99e-45	-	-	-	-	-	-	-	-
PELLHMED_00502	3.99e-88	-	-	-	-	-	-	-	-
PELLHMED_00503	1.48e-219	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
PELLHMED_00504	2.6e-19	-	-	-	-	-	-	-	-
PELLHMED_00505	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PELLHMED_00506	4.35e-207	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PELLHMED_00507	2.62e-111	-	-	-	M	-	-	-	LysM domain protein
PELLHMED_00508	3.81e-253	-	-	-	D	-	-	-	nuclear chromosome segregation
PELLHMED_00509	1e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PELLHMED_00510	2.57e-139	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
PELLHMED_00511	9.82e-156	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
PELLHMED_00512	9.11e-69	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PELLHMED_00513	7.11e-236	lacI	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PELLHMED_00514	0.0	-	-	-	G	ko:K02027,ko:K10120	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PELLHMED_00515	1.78e-209	-	-	-	P	ko:K10121	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
PELLHMED_00516	2.93e-199	msmG	-	-	G	ko:K02026,ko:K10122	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PELLHMED_00517	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
PELLHMED_00518	8.89e-270	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PELLHMED_00519	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PELLHMED_00520	3.18e-92	-	-	-	EGP	-	-	-	Major Facilitator
PELLHMED_00522	6.76e-227	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PELLHMED_00523	0.0	slpX	-	-	S	-	-	-	SLAP domain
PELLHMED_00526	5.81e-272	-	-	-	-	-	-	-	-
PELLHMED_00527	1.33e-160	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PELLHMED_00528	2.13e-92	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
PELLHMED_00529	1.39e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PELLHMED_00530	1.85e-264	-	-	-	M	-	-	-	Glycosyl transferases group 1
PELLHMED_00531	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PELLHMED_00532	5.7e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PELLHMED_00533	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PELLHMED_00534	3.89e-288	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PELLHMED_00535	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PELLHMED_00536	8.44e-177	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PELLHMED_00537	6.32e-83	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PELLHMED_00539	1.02e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PELLHMED_00540	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PELLHMED_00541	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PELLHMED_00542	7.29e-267	camS	-	-	S	-	-	-	sex pheromone
PELLHMED_00543	4.46e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PELLHMED_00544	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PELLHMED_00545	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PELLHMED_00546	2.37e-220	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PELLHMED_00547	8.38e-144	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PELLHMED_00548	4.94e-75	-	-	-	-	-	-	-	-
PELLHMED_00549	1.28e-310	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PELLHMED_00550	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PELLHMED_00551	4.2e-30	-	-	-	-	-	-	-	-
PELLHMED_00552	1.48e-82	-	-	-	-	-	-	-	-
PELLHMED_00553	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
PELLHMED_00554	5.51e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
PELLHMED_00555	1.05e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
PELLHMED_00556	9.1e-148	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
PELLHMED_00557	5.16e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
PELLHMED_00558	3.15e-62	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
PELLHMED_00559	2.43e-76	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
PELLHMED_00560	2.98e-246	-	-	-	L	ko:K06400	-	ko00000	Recombinase
PELLHMED_00561	3.28e-122	-	-	-	L	-	-	-	Resolvase, N terminal domain
PELLHMED_00562	9.05e-231	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
PELLHMED_00563	3.49e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PELLHMED_00568	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PELLHMED_00569	1.88e-174	-	-	-	S	-	-	-	CAAX protease self-immunity
PELLHMED_00570	1.25e-118	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PELLHMED_00571	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PELLHMED_00572	3.79e-101	-	-	-	K	-	-	-	acetyltransferase
PELLHMED_00573	4.73e-206	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PELLHMED_00574	5.13e-141	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PELLHMED_00575	5.81e-165	XK27_08575	-	-	V	ko:K06148	-	ko00000,ko02000	cysteine transport
PELLHMED_00576	5.36e-305	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PELLHMED_00577	1.39e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PELLHMED_00578	3.27e-110	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PELLHMED_00579	2.03e-67	-	3.1.3.102, 3.1.3.104	-	Q	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatase activity
PELLHMED_00580	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PELLHMED_00581	3.81e-274	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
PELLHMED_00582	1.11e-212	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PELLHMED_00583	7.56e-267	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
PELLHMED_00584	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PELLHMED_00585	1.4e-188	-	-	-	-	-	-	-	-
PELLHMED_00586	2.22e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PELLHMED_00587	6.57e-102	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PELLHMED_00588	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_00589	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
PELLHMED_00590	8.88e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PELLHMED_00591	1.92e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
PELLHMED_00592	2.39e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PELLHMED_00593	4.3e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PELLHMED_00594	1.43e-136	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PELLHMED_00595	8.28e-143	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PELLHMED_00596	3.66e-224	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
PELLHMED_00597	2.75e-95	-	-	-	-	-	-	-	-
PELLHMED_00598	5.02e-313	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PELLHMED_00599	5.34e-211	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PELLHMED_00600	9.2e-214	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PELLHMED_00601	3.83e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PELLHMED_00602	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PELLHMED_00603	3.51e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PELLHMED_00604	1.98e-175	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PELLHMED_00605	1.81e-28	-	-	-	-	-	-	-	-
PELLHMED_00606	5.7e-146	-	-	-	-	-	-	-	-
PELLHMED_00607	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PELLHMED_00608	2.07e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PELLHMED_00609	1.21e-93	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PELLHMED_00610	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PELLHMED_00611	7.73e-79	-	-	-	S	-	-	-	Enterocin A Immunity
PELLHMED_00612	3.4e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PELLHMED_00613	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PELLHMED_00614	2.25e-206	-	-	-	S	-	-	-	Phospholipase, patatin family
PELLHMED_00615	7.37e-293	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PELLHMED_00616	8.04e-187	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PELLHMED_00617	5.93e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PELLHMED_00618	1.35e-196	-	-	-	S	-	-	-	hydrolase
PELLHMED_00619	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PELLHMED_00620	1.1e-191	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PELLHMED_00621	2.25e-105	-	-	-	-	-	-	-	-
PELLHMED_00622	5.61e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PELLHMED_00623	1.51e-53	-	-	-	-	-	-	-	-
PELLHMED_00624	9.09e-156	-	-	-	C	-	-	-	nitroreductase
PELLHMED_00625	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
PELLHMED_00626	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PELLHMED_00627	0.0	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PELLHMED_00628	3.27e-294	-	-	-	E	ko:K03294	-	ko00000	amino acid
PELLHMED_00629	9.79e-168	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PELLHMED_00630	2.35e-269	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PELLHMED_00631	5.88e-312	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PELLHMED_00633	2.81e-279	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PELLHMED_00634	4.67e-116	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
PELLHMED_00635	8.53e-104	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PELLHMED_00636	7.02e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PELLHMED_00637	1.14e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PELLHMED_00638	6.78e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PELLHMED_00639	3.81e-275	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PELLHMED_00640	3.42e-278	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PELLHMED_00641	3.82e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PELLHMED_00642	2.95e-61	-	-	-	-	-	-	-	-
PELLHMED_00643	2.13e-227	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PELLHMED_00644	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PELLHMED_00645	4.13e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PELLHMED_00646	7.42e-112	-	-	-	-	-	-	-	-
PELLHMED_00647	1.02e-93	-	-	-	-	-	-	-	-
PELLHMED_00648	1.24e-201	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
PELLHMED_00649	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PELLHMED_00650	3.43e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PELLHMED_00651	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PELLHMED_00652	9.05e-55	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PELLHMED_00653	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PELLHMED_00654	1.08e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PELLHMED_00655	2.91e-175	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PELLHMED_00656	2.56e-209	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PELLHMED_00657	7.54e-149	yjbH	-	-	Q	-	-	-	Thioredoxin
PELLHMED_00658	1.46e-145	-	-	-	S	-	-	-	CYTH
PELLHMED_00659	1.15e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PELLHMED_00660	5.49e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PELLHMED_00661	1.81e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PELLHMED_00662	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PELLHMED_00663	8.93e-153	-	-	-	S	-	-	-	SNARE associated Golgi protein
PELLHMED_00664	1.06e-257	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PELLHMED_00665	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PELLHMED_00666	8.1e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PELLHMED_00667	8.9e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
PELLHMED_00668	1.75e-134	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PELLHMED_00669	1.28e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
PELLHMED_00670	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PELLHMED_00671	4.09e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PELLHMED_00672	2.26e-306	ymfH	-	-	S	-	-	-	Peptidase M16
PELLHMED_00673	8.02e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PELLHMED_00674	1.43e-160	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PELLHMED_00675	1.73e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PELLHMED_00676	6.24e-247	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PELLHMED_00677	1.29e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PELLHMED_00678	3.37e-271	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
PELLHMED_00679	2.05e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PELLHMED_00680	8.33e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PELLHMED_00681	7.21e-173	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PELLHMED_00682	1.75e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PELLHMED_00683	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PELLHMED_00684	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PELLHMED_00685	1.88e-21	-	-	-	-	-	-	-	-
PELLHMED_00686	6.85e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PELLHMED_00687	4.36e-205	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PELLHMED_00688	1.71e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PELLHMED_00689	9.38e-228	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PELLHMED_00690	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PELLHMED_00691	4.02e-284	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PELLHMED_00692	5.82e-272	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
PELLHMED_00693	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
PELLHMED_00694	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PELLHMED_00695	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PELLHMED_00696	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PELLHMED_00697	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PELLHMED_00698	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PELLHMED_00699	3.8e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PELLHMED_00700	6e-212	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PELLHMED_00701	3.24e-250	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PELLHMED_00702	1.17e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PELLHMED_00703	2.16e-129	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PELLHMED_00704	0.0	-	-	-	S	-	-	-	SH3-like domain
PELLHMED_00705	0.0	ycaM	-	-	E	-	-	-	amino acid
PELLHMED_00707	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
PELLHMED_00708	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PELLHMED_00709	9.96e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PELLHMED_00710	2.71e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PELLHMED_00711	1.07e-125	-	-	-	-	-	-	-	-
PELLHMED_00712	1.02e-202	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PELLHMED_00713	1.15e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PELLHMED_00714	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PELLHMED_00715	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PELLHMED_00716	5.26e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PELLHMED_00717	7.27e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PELLHMED_00718	2.94e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PELLHMED_00719	1.04e-180	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PELLHMED_00720	2.65e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PELLHMED_00721	9.5e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PELLHMED_00722	1.06e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PELLHMED_00723	3.38e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
PELLHMED_00724	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PELLHMED_00725	4.85e-191	-	-	-	S	-	-	-	hydrolase
PELLHMED_00726	1.45e-187	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PELLHMED_00727	7.3e-156	-	-	-	-	-	-	-	-
PELLHMED_00728	2.73e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PELLHMED_00729	1.37e-269	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PELLHMED_00730	4.66e-196	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PELLHMED_00731	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PELLHMED_00732	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PELLHMED_00733	6.14e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PELLHMED_00734	0.0	-	-	-	E	-	-	-	Amino acid permease
PELLHMED_00736	1.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PELLHMED_00737	2.34e-119	-	-	-	S	-	-	-	VanZ like family
PELLHMED_00738	1.97e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PELLHMED_00739	1.38e-228	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PELLHMED_00740	5.57e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PELLHMED_00741	1.55e-65	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
PELLHMED_00742	9e-94	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
PELLHMED_00743	1.33e-25	-	-	-	-	-	-	-	-
PELLHMED_00744	2.61e-120	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
PELLHMED_00745	4.19e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PELLHMED_00746	1.35e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PELLHMED_00748	1.05e-170	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
PELLHMED_00749	3.52e-224	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PELLHMED_00750	4.53e-41	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PELLHMED_00751	1.86e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PELLHMED_00752	1.68e-81	-	-	-	S	-	-	-	SdpI/YhfL protein family
PELLHMED_00753	1.97e-170	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PELLHMED_00754	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PELLHMED_00755	4.37e-81	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PELLHMED_00756	1.53e-159	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PELLHMED_00757	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PELLHMED_00758	1.93e-139	vanZ	-	-	V	-	-	-	VanZ like family
PELLHMED_00759	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PELLHMED_00760	5.4e-316	-	-	-	EGP	-	-	-	Major Facilitator
PELLHMED_00761	7.36e-251	ampC	-	-	V	-	-	-	Beta-lactamase
PELLHMED_00764	2.17e-85	-	-	-	-	-	-	-	-
PELLHMED_00765	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
PELLHMED_00766	1.18e-47	-	-	-	-	-	-	-	-
PELLHMED_00767	6.8e-46	-	-	-	-	-	-	-	-
PELLHMED_00768	3.84e-90	-	-	-	-	-	-	-	-
PELLHMED_00769	2.58e-49	-	-	-	-	-	-	-	-
PELLHMED_00771	3.5e-75	-	-	-	K	-	-	-	Transcriptional
PELLHMED_00772	1.58e-266	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PELLHMED_00773	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
PELLHMED_00774	4.64e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PELLHMED_00775	1.01e-235	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PELLHMED_00776	2.52e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PELLHMED_00777	4.93e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PELLHMED_00778	1.84e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PELLHMED_00779	4.13e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PELLHMED_00780	4.36e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PELLHMED_00781	4.97e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PELLHMED_00782	6.82e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PELLHMED_00783	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PELLHMED_00784	1.22e-220	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PELLHMED_00785	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PELLHMED_00786	7.03e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PELLHMED_00787	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PELLHMED_00788	2.04e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PELLHMED_00789	7.58e-67	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PELLHMED_00790	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PELLHMED_00791	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PELLHMED_00792	6.39e-102	uspA	-	-	T	-	-	-	universal stress protein
PELLHMED_00793	1.41e-49	-	-	-	-	-	-	-	-
PELLHMED_00794	1.18e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PELLHMED_00795	9.44e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PELLHMED_00796	1.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PELLHMED_00797	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PELLHMED_00798	1.29e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PELLHMED_00799	4.62e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PELLHMED_00800	1.56e-165	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PELLHMED_00801	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PELLHMED_00802	2.55e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PELLHMED_00803	1.83e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PELLHMED_00804	2.34e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PELLHMED_00805	2.03e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PELLHMED_00806	1.82e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PELLHMED_00807	6.61e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
PELLHMED_00808	1.45e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
PELLHMED_00809	4.84e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
PELLHMED_00810	3.95e-93	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PELLHMED_00811	5.41e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PELLHMED_00812	1.32e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
PELLHMED_00813	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PELLHMED_00814	8e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PELLHMED_00815	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PELLHMED_00816	4.93e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PELLHMED_00817	1.71e-182	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PELLHMED_00818	1.02e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PELLHMED_00819	5.9e-313	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PELLHMED_00820	4.09e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PELLHMED_00821	1.36e-39	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PELLHMED_00822	4.87e-193	ylmH	-	-	S	-	-	-	S4 domain protein
PELLHMED_00823	1.18e-141	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PELLHMED_00824	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PELLHMED_00825	8.09e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PELLHMED_00826	6.29e-135	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PELLHMED_00827	4.49e-42	-	-	-	-	-	-	-	-
PELLHMED_00828	1.02e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PELLHMED_00829	1.47e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PELLHMED_00830	1.62e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PELLHMED_00831	1.58e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
PELLHMED_00832	2.93e-150	-	-	-	S	-	-	-	repeat protein
PELLHMED_00833	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PELLHMED_00834	0.0	-	-	-	L	-	-	-	Nuclease-related domain
PELLHMED_00835	1.29e-233	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PELLHMED_00836	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PELLHMED_00837	3.13e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PELLHMED_00838	2.52e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PELLHMED_00839	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PELLHMED_00840	2.75e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PELLHMED_00841	4.73e-69	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PELLHMED_00842	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PELLHMED_00843	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PELLHMED_00844	1.37e-246	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PELLHMED_00845	2.19e-131	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PELLHMED_00846	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PELLHMED_00847	3.38e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PELLHMED_00848	3.78e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PELLHMED_00849	4.08e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PELLHMED_00850	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PELLHMED_00851	1.45e-195	-	-	-	-	-	-	-	-
PELLHMED_00852	8.19e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PELLHMED_00853	3.02e-294	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PELLHMED_00854	8.42e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PELLHMED_00855	1.17e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PELLHMED_00856	7.3e-245	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PELLHMED_00857	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PELLHMED_00858	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PELLHMED_00859	1.39e-106	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PELLHMED_00860	5.48e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PELLHMED_00861	1.14e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PELLHMED_00862	1.23e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PELLHMED_00863	2.42e-281	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PELLHMED_00864	4.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PELLHMED_00865	8.12e-262	pbpX1	-	-	V	-	-	-	Beta-lactamase
PELLHMED_00866	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
PELLHMED_00867	1.18e-55	-	-	-	C	-	-	-	FMN_bind
PELLHMED_00868	1.01e-104	-	-	-	-	-	-	-	-
PELLHMED_00869	0.0	-	-	-	-	-	-	-	-
PELLHMED_00870	4.65e-228	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
PELLHMED_00871	8.04e-188	-	-	-	-	-	-	-	-
PELLHMED_00875	1.93e-25	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
PELLHMED_00876	4.23e-93	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
PELLHMED_00877	3.08e-52	-	-	-	S	-	-	-	Transglycosylase associated protein
PELLHMED_00878	6.28e-10	-	-	-	S	-	-	-	CsbD-like
PELLHMED_00879	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PELLHMED_00880	1.62e-166	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
PELLHMED_00881	4.98e-74	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PELLHMED_00882	4.75e-80	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
PELLHMED_00883	4.68e-104	-	-	-	-	-	-	-	-
PELLHMED_00884	1.68e-179	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PELLHMED_00885	2.84e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PELLHMED_00886	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PELLHMED_00887	1.45e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
PELLHMED_00888	1.91e-55	-	-	-	-	-	-	-	-
PELLHMED_00889	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PELLHMED_00890	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PELLHMED_00891	3.69e-207	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PELLHMED_00892	1.01e-111	yfhC	-	-	C	-	-	-	Nitroreductase family
PELLHMED_00893	4.93e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PELLHMED_00894	2.12e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PELLHMED_00895	1.19e-194	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PELLHMED_00896	2.64e-128	-	-	-	I	-	-	-	PAP2 superfamily
PELLHMED_00897	1.47e-244	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PELLHMED_00899	2.59e-229	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PELLHMED_00900	1.09e-34	-	-	-	-	-	-	-	-
PELLHMED_00901	1.98e-129	-	-	-	-	-	-	-	-
PELLHMED_00902	0.000281	-	-	-	-	-	-	-	-
PELLHMED_00903	9.27e-75	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PELLHMED_00904	2.16e-39	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PELLHMED_00905	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PELLHMED_00906	1.21e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PELLHMED_00907	1.53e-122	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PELLHMED_00908	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PELLHMED_00909	1.03e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PELLHMED_00910	2.07e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PELLHMED_00911	4.45e-127	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PELLHMED_00912	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PELLHMED_00913	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PELLHMED_00914	0.0	-	-	-	M	-	-	-	domain protein
PELLHMED_00915	5.14e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PELLHMED_00916	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PELLHMED_00917	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PELLHMED_00918	7.54e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
PELLHMED_00919	7.35e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PELLHMED_00920	2.76e-60	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
PELLHMED_00921	6.24e-215	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
PELLHMED_00922	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
PELLHMED_00923	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
PELLHMED_00924	6.03e-19	-	-	-	-	-	-	-	-
PELLHMED_00925	1.14e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PELLHMED_00926	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PELLHMED_00927	4.42e-124	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
PELLHMED_00928	2.09e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
PELLHMED_00929	5.21e-71	-	-	-	-	-	-	-	-
PELLHMED_00930	1.56e-228	citR	-	-	K	-	-	-	Putative sugar-binding domain
PELLHMED_00931	3.82e-312	-	-	-	S	-	-	-	Putative threonine/serine exporter
PELLHMED_00932	7.54e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PELLHMED_00933	1.32e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PELLHMED_00934	1.17e-65	-	-	-	-	-	-	-	-
PELLHMED_00935	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PELLHMED_00936	2.56e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PELLHMED_00937	1.74e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PELLHMED_00938	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PELLHMED_00939	9.94e-287	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PELLHMED_00940	1.03e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PELLHMED_00941	2.72e-197	-	-	-	S	-	-	-	reductase
PELLHMED_00942	3.29e-193	yxeH	-	-	S	-	-	-	hydrolase
PELLHMED_00943	2.31e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PELLHMED_00944	5.04e-298	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PELLHMED_00945	4.52e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
PELLHMED_00946	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PELLHMED_00947	3.01e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PELLHMED_00948	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PELLHMED_00949	6.35e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PELLHMED_00950	1.5e-186	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PELLHMED_00951	2.25e-45	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PELLHMED_00952	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PELLHMED_00953	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PELLHMED_00954	3.9e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PELLHMED_00955	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PELLHMED_00956	7.76e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PELLHMED_00957	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PELLHMED_00958	1e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PELLHMED_00959	2.19e-218	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PELLHMED_00960	6.56e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PELLHMED_00961	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PELLHMED_00962	5.75e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PELLHMED_00963	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PELLHMED_00964	6.79e-152	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PELLHMED_00965	7.33e-71	-	-	-	M	-	-	-	Lysin motif
PELLHMED_00966	1.28e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PELLHMED_00967	4.07e-270	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PELLHMED_00968	3.15e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PELLHMED_00969	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PELLHMED_00970	2.22e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PELLHMED_00971	1.3e-207	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PELLHMED_00972	8.15e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PELLHMED_00973	7.33e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PELLHMED_00974	6.34e-193	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PELLHMED_00975	1.64e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PELLHMED_00976	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PELLHMED_00977	8.81e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PELLHMED_00978	8.96e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PELLHMED_00979	1.07e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PELLHMED_00980	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PELLHMED_00981	2.09e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PELLHMED_00982	2.27e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
PELLHMED_00983	3.29e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PELLHMED_00984	4.61e-308	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PELLHMED_00985	7.16e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PELLHMED_00986	1.72e-85	-	-	-	-	-	-	-	-
PELLHMED_00987	4.82e-296	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PELLHMED_00988	1.25e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PELLHMED_00989	2.82e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PELLHMED_00990	7.42e-89	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PELLHMED_00991	9.18e-83	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PELLHMED_00992	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PELLHMED_00993	0.0	-	-	-	E	-	-	-	Amino acid permease
PELLHMED_00994	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
PELLHMED_00995	1.13e-312	ynbB	-	-	P	-	-	-	aluminum resistance
PELLHMED_00996	6.35e-154	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
PELLHMED_00997	7.3e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
PELLHMED_00998	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PELLHMED_00999	1.47e-105	-	-	-	C	-	-	-	Flavodoxin
PELLHMED_01000	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
PELLHMED_01001	4.33e-234	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PELLHMED_01002	8.43e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
PELLHMED_01003	5.22e-89	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PELLHMED_01004	1.71e-265	-	-	-	V	-	-	-	Beta-lactamase
PELLHMED_01005	2.42e-201	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PELLHMED_01006	2.46e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PELLHMED_01007	1.84e-281	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PELLHMED_01008	5.05e-313	-	-	-	-	-	-	-	-
PELLHMED_01009	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PELLHMED_01010	2.78e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PELLHMED_01011	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PELLHMED_01012	5.68e-165	-	-	-	M	-	-	-	Glycosyl transferases group 1
PELLHMED_01013	5.84e-129	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PELLHMED_01014	7.57e-211	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PELLHMED_01015	2.61e-19	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PELLHMED_01016	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PELLHMED_01017	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PELLHMED_01018	9.5e-39	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PELLHMED_01019	1.72e-208	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
PELLHMED_01020	5.93e-149	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
PELLHMED_01021	5.96e-205	-	-	-	K	-	-	-	Transcriptional regulator
PELLHMED_01022	6.27e-215	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
PELLHMED_01023	1.08e-212	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PELLHMED_01024	1.31e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
PELLHMED_01025	5.42e-275	-	-	-	S	-	-	-	SLAP domain
PELLHMED_01026	1.7e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PELLHMED_01029	2.77e-134	-	-	-	-	-	-	-	-
PELLHMED_01030	2.07e-102	-	-	-	K	-	-	-	Transcriptional regulator
PELLHMED_01031	8.07e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PELLHMED_01032	3.34e-211	-	-	-	S	-	-	-	reductase
PELLHMED_01033	2.77e-220	-	-	-	-	-	-	-	-
PELLHMED_01034	4.2e-42	lysR	-	-	K	-	-	-	Transcriptional regulator
PELLHMED_01035	3.25e-145	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
PELLHMED_01036	2.48e-131	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
PELLHMED_01037	6.13e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01038	3.59e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PELLHMED_01039	2.66e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PELLHMED_01040	1.72e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PELLHMED_01041	1.81e-223	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
PELLHMED_01042	5.1e-43	-	-	-	-	-	-	-	-
PELLHMED_01043	1.41e-141	-	-	-	-	-	-	-	-
PELLHMED_01044	3.18e-140	-	-	-	-	-	-	-	-
PELLHMED_01045	3.18e-167	-	-	-	F	-	-	-	glutamine amidotransferase
PELLHMED_01046	9.73e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PELLHMED_01047	1.7e-199	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
PELLHMED_01048	2.53e-152	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PELLHMED_01049	2.43e-100	-	-	-	-	-	-	-	-
PELLHMED_01050	1.24e-113	-	-	-	FG	-	-	-	HIT domain
PELLHMED_01051	5.21e-82	-	-	-	-	-	-	-	-
PELLHMED_01052	4.91e-121	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PELLHMED_01053	1.62e-135	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PELLHMED_01054	6.2e-131	-	-	-	-	-	-	-	-
PELLHMED_01055	1.22e-103	-	-	-	-	-	-	-	-
PELLHMED_01056	2.72e-188	-	-	-	F	-	-	-	Phosphorylase superfamily
PELLHMED_01057	3.34e-139	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
PELLHMED_01058	2.07e-189	-	-	-	F	-	-	-	Phosphorylase superfamily
PELLHMED_01059	1.06e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
PELLHMED_01060	1.79e-144	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
PELLHMED_01061	1.24e-47	-	-	-	-	-	-	-	-
PELLHMED_01062	2.58e-67	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
PELLHMED_01063	9.6e-137	-	-	-	-	-	-	-	-
PELLHMED_01064	8.78e-52	-	-	-	-	-	-	-	-
PELLHMED_01065	3.77e-216	mleR	-	-	K	-	-	-	LysR family
PELLHMED_01066	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PELLHMED_01067	3.74e-130	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PELLHMED_01068	2.2e-310	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
PELLHMED_01069	2.27e-248	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PELLHMED_01070	5.33e-147	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
PELLHMED_01071	1.23e-278	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PELLHMED_01072	3.03e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PELLHMED_01073	2.55e-118	-	-	-	L	-	-	-	nuclease
PELLHMED_01074	2.51e-198	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PELLHMED_01075	2.81e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PELLHMED_01076	5.39e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PELLHMED_01077	4.4e-138	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PELLHMED_01078	6.01e-54	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PELLHMED_01079	3.16e-190	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PELLHMED_01080	0.0	ppc	4.1.1.31	-	C	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate carboxylase activity
PELLHMED_01081	0.0	-	-	-	-	-	-	-	-
PELLHMED_01082	0.0	-	-	-	-	-	-	-	-
PELLHMED_01083	2.29e-224	yobV3	-	-	K	-	-	-	WYL domain
PELLHMED_01084	4.35e-108	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
PELLHMED_01085	1.57e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
PELLHMED_01086	3.78e-72	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PELLHMED_01087	1.16e-148	-	-	-	C	-	-	-	Aldo/keto reductase family
PELLHMED_01088	7.12e-80	-	-	-	C	-	-	-	aldo keto reductase
PELLHMED_01089	1.54e-187	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
PELLHMED_01090	1.51e-24	-	-	-	C	-	-	-	Flavodoxin
PELLHMED_01092	9.87e-139	-	-	-	C	-	-	-	Flavodoxin
PELLHMED_01093	2.88e-130	-	-	-	P	-	-	-	esterase
PELLHMED_01094	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PELLHMED_01095	3.77e-32	-	-	-	-	-	-	-	-
PELLHMED_01096	1.29e-182	-	-	-	C	-	-	-	Flavodoxin
PELLHMED_01097	7.38e-127	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
PELLHMED_01098	3.1e-30	-	-	-	C	-	-	-	Flavodoxin
PELLHMED_01099	1.39e-190	-	-	-	P	-	-	-	FAD-binding domain
PELLHMED_01100	2.54e-101	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PELLHMED_01102	0.0	yagE	-	-	E	-	-	-	amino acid
PELLHMED_01103	1.37e-15	-	-	-	S	-	-	-	Alpha beta hydrolase
PELLHMED_01104	6e-59	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PELLHMED_01105	4.13e-18	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PELLHMED_01106	1.43e-24	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
PELLHMED_01107	8.53e-215	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PELLHMED_01108	1.17e-130	-	-	-	-	-	-	-	-
PELLHMED_01109	1.9e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PELLHMED_01110	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PELLHMED_01111	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PELLHMED_01112	3.72e-237	-	-	-	K	-	-	-	Transcriptional regulator
PELLHMED_01113	3.65e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PELLHMED_01114	7.02e-146	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PELLHMED_01115	9.73e-55	-	-	-	K	-	-	-	Helix-turn-helix domain
PELLHMED_01116	4.78e-165	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PELLHMED_01117	3.46e-87	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
PELLHMED_01119	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PELLHMED_01120	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PELLHMED_01121	1.74e-272	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PELLHMED_01122	1.06e-110	rmaD	-	-	K	-	-	-	transcriptional
PELLHMED_01123	3.92e-76	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PELLHMED_01124	3.43e-07	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PELLHMED_01125	2.71e-256	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PELLHMED_01126	2.62e-138	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
PELLHMED_01127	1.27e-119	flaR	-	-	F	-	-	-	topology modulation protein
PELLHMED_01128	1.03e-100	-	-	-	-	-	-	-	-
PELLHMED_01129	5.95e-250	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PELLHMED_01130	6.18e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
PELLHMED_01131	2.95e-87	-	-	-	-	-	-	-	-
PELLHMED_01132	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PELLHMED_01133	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PELLHMED_01134	2.05e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PELLHMED_01135	2.88e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PELLHMED_01136	6.03e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PELLHMED_01137	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PELLHMED_01138	2.01e-310	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PELLHMED_01139	2.39e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PELLHMED_01140	2.83e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PELLHMED_01141	1.61e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PELLHMED_01142	1.99e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PELLHMED_01143	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PELLHMED_01144	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PELLHMED_01145	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PELLHMED_01146	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PELLHMED_01147	8.23e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PELLHMED_01148	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PELLHMED_01149	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PELLHMED_01150	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PELLHMED_01151	6.78e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
PELLHMED_01152	3.39e-227	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PELLHMED_01153	1.64e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PELLHMED_01154	2.09e-242	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PELLHMED_01155	1.01e-187	-	-	-	K	-	-	-	SIS domain
PELLHMED_01156	1.18e-140	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PELLHMED_01157	2.04e-73	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PELLHMED_01158	1.14e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PELLHMED_01159	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PELLHMED_01160	1.05e-228	-	-	-	-	-	-	-	-
PELLHMED_01161	1.57e-181	-	-	-	-	-	-	-	-
PELLHMED_01162	1.72e-123	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PELLHMED_01163	1.04e-37	-	-	-	-	-	-	-	-
PELLHMED_01164	3.64e-175	-	-	-	-	-	-	-	-
PELLHMED_01165	2.03e-186	-	-	-	-	-	-	-	-
PELLHMED_01166	1.51e-174	-	-	-	-	-	-	-	-
PELLHMED_01167	1.09e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PELLHMED_01168	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
PELLHMED_01169	7.64e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PELLHMED_01170	3.45e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PELLHMED_01171	4.48e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PELLHMED_01172	1.87e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PELLHMED_01173	2.24e-162	-	-	-	S	-	-	-	Peptidase family M23
PELLHMED_01174	3.01e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PELLHMED_01175	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PELLHMED_01176	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PELLHMED_01177	1.05e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PELLHMED_01178	5.41e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PELLHMED_01179	6.28e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PELLHMED_01180	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PELLHMED_01181	1.82e-226	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PELLHMED_01182	4.38e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PELLHMED_01183	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PELLHMED_01184	4.68e-197	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PELLHMED_01185	3.22e-133	-	-	-	S	-	-	-	Peptidase family M23
PELLHMED_01186	6.31e-144	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PELLHMED_01187	2.17e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PELLHMED_01188	1.4e-157	-	-	-	-	-	-	-	-
PELLHMED_01189	4.04e-207	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PELLHMED_01190	1.58e-282	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PELLHMED_01191	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
PELLHMED_01192	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PELLHMED_01193	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PELLHMED_01194	3.65e-28	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
PELLHMED_01195	1.92e-141	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PELLHMED_01196	0.0	-	-	-	-	ko:K14201	ko05150,map05150	ko00000,ko00001	-
PELLHMED_01197	2.86e-05	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
PELLHMED_01198	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
PELLHMED_01199	5.4e-282	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PELLHMED_01200	0.0	-	-	-	-	-	-	-	-
PELLHMED_01201	3.69e-157	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
PELLHMED_01202	8.29e-129	-	-	-	-	-	-	-	-
PELLHMED_01203	1.82e-139	-	-	-	K	-	-	-	LysR substrate binding domain
PELLHMED_01204	8.62e-22	-	-	-	-	-	-	-	-
PELLHMED_01205	3.35e-291	-	-	-	S	-	-	-	Sterol carrier protein domain
PELLHMED_01206	3.83e-127	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PELLHMED_01207	3.72e-201	lysR5	-	-	K	-	-	-	LysR substrate binding domain
PELLHMED_01208	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PELLHMED_01209	1.19e-113	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
PELLHMED_01210	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PELLHMED_01211	4.53e-196	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PELLHMED_01212	1.73e-219	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PELLHMED_01213	1.72e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PELLHMED_01214	6.15e-194	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PELLHMED_01216	7.02e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PELLHMED_01217	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PELLHMED_01218	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PELLHMED_01219	6.07e-155	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PELLHMED_01220	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PELLHMED_01221	5.85e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PELLHMED_01222	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PELLHMED_01223	7.55e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PELLHMED_01224	2.1e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PELLHMED_01225	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PELLHMED_01226	2.49e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PELLHMED_01227	8.54e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PELLHMED_01228	9.65e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PELLHMED_01229	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PELLHMED_01230	3.95e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
PELLHMED_01231	6.47e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PELLHMED_01232	3.76e-268	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PELLHMED_01233	2.39e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PELLHMED_01234	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PELLHMED_01235	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PELLHMED_01236	1.35e-255	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PELLHMED_01237	1.89e-188	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PELLHMED_01238	2.23e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PELLHMED_01239	2.53e-114	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PELLHMED_01240	7.13e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PELLHMED_01241	1.45e-234	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PELLHMED_01242	2.05e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PELLHMED_01243	6.34e-255	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PELLHMED_01244	1.59e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PELLHMED_01245	9.32e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PELLHMED_01246	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PELLHMED_01247	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PELLHMED_01248	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PELLHMED_01249	3.18e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
PELLHMED_01250	2.97e-50	ynzC	-	-	S	-	-	-	UPF0291 protein
PELLHMED_01251	2.83e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PELLHMED_01252	1.4e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PELLHMED_01253	1.19e-156	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
PELLHMED_01254	2.58e-226	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PELLHMED_01255	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PELLHMED_01256	3.52e-91	-	-	-	S	-	-	-	GtrA-like protein
PELLHMED_01257	2.28e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PELLHMED_01258	5.01e-164	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PELLHMED_01259	1.07e-124	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PELLHMED_01260	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PELLHMED_01261	1.9e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PELLHMED_01262	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PELLHMED_01263	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
PELLHMED_01264	1.16e-88	-	-	-	-	-	-	-	-
PELLHMED_01265	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PELLHMED_01266	1.12e-228	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PELLHMED_01267	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PELLHMED_01268	4.48e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PELLHMED_01269	0.0	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PELLHMED_01270	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PELLHMED_01271	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PELLHMED_01272	5.84e-202	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PELLHMED_01273	1.28e-226	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PELLHMED_01274	8.73e-234	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PELLHMED_01275	1.43e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PELLHMED_01276	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PELLHMED_01277	3.16e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PELLHMED_01278	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PELLHMED_01279	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PELLHMED_01280	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PELLHMED_01281	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PELLHMED_01282	1.5e-68	-	-	-	-	-	-	-	-
PELLHMED_01283	3.29e-163	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PELLHMED_01284	5.27e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PELLHMED_01285	1.37e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PELLHMED_01286	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PELLHMED_01287	9.79e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PELLHMED_01288	4.61e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PELLHMED_01289	1.08e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PELLHMED_01290	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PELLHMED_01291	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PELLHMED_01292	2.53e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PELLHMED_01293	2.88e-105	-	-	-	S	-	-	-	ASCH
PELLHMED_01294	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PELLHMED_01295	1.52e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PELLHMED_01296	1.84e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PELLHMED_01297	3.76e-48	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PELLHMED_01298	5.86e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PELLHMED_01299	5.91e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PELLHMED_01300	1.28e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PELLHMED_01301	2.57e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PELLHMED_01302	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PELLHMED_01303	3.69e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PELLHMED_01304	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PELLHMED_01305	4.8e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PELLHMED_01306	3.54e-192	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PELLHMED_01307	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PELLHMED_01308	3.98e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PELLHMED_01309	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PELLHMED_01310	4.41e-137	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
PELLHMED_01311	9.64e-141	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
PELLHMED_01312	7.45e-09	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PELLHMED_01313	9.58e-80	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PELLHMED_01314	7.38e-127	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PELLHMED_01315	3.88e-196	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
PELLHMED_01316	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PELLHMED_01317	3.04e-198	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
PELLHMED_01318	1.16e-162	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PELLHMED_01319	1.75e-95	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PELLHMED_01321	4.22e-211	-	-	-	S	-	-	-	Membrane
PELLHMED_01322	1.75e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
PELLHMED_01323	4.8e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
PELLHMED_01324	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PELLHMED_01325	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PELLHMED_01326	1.84e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PELLHMED_01327	1.64e-262	-	-	-	-	-	-	-	-
PELLHMED_01328	1.71e-211	-	-	-	-	-	-	-	-
PELLHMED_01329	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PELLHMED_01330	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
PELLHMED_01331	0.0	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PELLHMED_01332	7.89e-213	-	2.7.1.85	-	GK	ko:K18673	-	ko00000,ko01000	ROK family
PELLHMED_01333	3.58e-262	xylR	-	-	GK	-	-	-	ROK family
PELLHMED_01334	4.19e-302	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PELLHMED_01335	9.35e-128	-	-	-	S	-	-	-	Bacterial PH domain
PELLHMED_01336	3.5e-22	-	-	-	-	-	-	-	-
PELLHMED_01337	1.02e-85	-	-	-	K	-	-	-	sequence-specific DNA binding
PELLHMED_01338	2.45e-63	-	-	-	S	-	-	-	Motility quorum-sensing regulator, toxin of MqsA
PELLHMED_01339	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PELLHMED_01340	1.67e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PELLHMED_01341	2.43e-62	-	-	-	-	-	-	-	-
PELLHMED_01342	1.74e-192	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PELLHMED_01343	0.0	-	-	-	-	-	-	-	-
PELLHMED_01344	2.73e-07	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PELLHMED_01345	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PELLHMED_01346	2.85e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PELLHMED_01347	5.02e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PELLHMED_01348	3.43e-235	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PELLHMED_01349	1.75e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PELLHMED_01350	1.94e-215	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PELLHMED_01351	7.44e-168	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PELLHMED_01352	2.73e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PELLHMED_01353	3.3e-152	-	-	-	GM	-	-	-	NmrA-like family
PELLHMED_01354	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PELLHMED_01355	9.28e-317	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PELLHMED_01356	1.86e-141	-	-	-	O	-	-	-	Matrixin
PELLHMED_01357	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PELLHMED_01358	3.89e-122	-	-	-	K	-	-	-	acetyltransferase
PELLHMED_01359	1.65e-66	-	-	-	-	-	-	-	-
PELLHMED_01360	2.34e-204	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PELLHMED_01361	2.87e-62	-	-	-	-	-	-	-	-
PELLHMED_01362	7.22e-161	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PELLHMED_01363	1.15e-200	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PELLHMED_01364	2.66e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PELLHMED_01365	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PELLHMED_01367	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PELLHMED_01368	7.81e-82	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
PELLHMED_01369	3.88e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PELLHMED_01370	1.77e-150	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
PELLHMED_01371	2.97e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PELLHMED_01372	1.08e-85	-	-	-	S	-	-	-	ASCH domain
PELLHMED_01373	6.71e-153	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PELLHMED_01375	1.3e-206	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
PELLHMED_01376	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
PELLHMED_01379	2.26e-267	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
PELLHMED_01380	1.63e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PELLHMED_01381	8.74e-192	-	-	-	T	-	-	-	EAL domain
PELLHMED_01382	8.31e-313	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
PELLHMED_01383	3.07e-119	-	-	-	-	-	-	-	-
PELLHMED_01384	9.37e-227	-	-	-	C	-	-	-	Oxidoreductase
PELLHMED_01386	4.69e-271	-	-	-	L	ko:K07496	-	ko00000	TIGRFAM transposase, IS605 OrfB family
PELLHMED_01387	4.27e-37	-	-	-	C	-	-	-	pentaerythritol trinitrate reductase activity
PELLHMED_01388	4.83e-141	pncA	-	-	Q	-	-	-	Isochorismatase family
PELLHMED_01389	2.86e-19	-	-	-	-	-	-	-	-
PELLHMED_01390	0.0	potE	-	-	E	-	-	-	Amino Acid
PELLHMED_01391	2.05e-163	-	-	-	S	-	-	-	Alpha beta hydrolase
PELLHMED_01393	1.31e-165	-	-	-	-	-	-	-	-
PELLHMED_01394	5.44e-163	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
PELLHMED_01395	8.84e-93	-	-	-	O	-	-	-	OsmC-like protein
PELLHMED_01396	3.65e-272	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PELLHMED_01397	9.45e-298	sptS	-	-	T	-	-	-	Histidine kinase
PELLHMED_01398	1.28e-152	dltr	-	-	K	-	-	-	response regulator
PELLHMED_01399	4.2e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
PELLHMED_01400	7.55e-241	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
PELLHMED_01401	1.31e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
PELLHMED_01402	8.2e-81	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
PELLHMED_01403	1.63e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PELLHMED_01404	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PELLHMED_01405	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PELLHMED_01406	3.33e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PELLHMED_01407	3.56e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PELLHMED_01408	1.98e-200	msmF	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PELLHMED_01409	6.26e-309	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PELLHMED_01410	7.27e-206	lacR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PELLHMED_01411	2.78e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PELLHMED_01412	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PELLHMED_01413	4.02e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PELLHMED_01414	9.46e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
PELLHMED_01415	1.53e-61	-	-	-	-	-	-	-	-
PELLHMED_01417	3.46e-53	-	-	-	C	-	-	-	FMN binding
PELLHMED_01418	1.42e-215	-	-	-	S	-	-	-	SLAP domain
PELLHMED_01419	6.76e-247	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PELLHMED_01420	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PELLHMED_01421	7.5e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PELLHMED_01422	9.91e-241	-	-	-	M	-	-	-	domain protein
PELLHMED_01423	1.51e-145	-	-	-	-	-	-	-	-
PELLHMED_01424	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PELLHMED_01425	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PELLHMED_01426	4.91e-287	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PELLHMED_01427	1.46e-240	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PELLHMED_01428	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PELLHMED_01429	8.15e-242	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
PELLHMED_01430	1.79e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PELLHMED_01431	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
PELLHMED_01432	1.05e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
PELLHMED_01433	2.88e-223	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PELLHMED_01434	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain
PELLHMED_01435	2e-79	-	-	-	G	-	-	-	polysaccharide catabolic process
PELLHMED_01436	0.0	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PELLHMED_01437	9.97e-103	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
PELLHMED_01438	4.63e-225	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PELLHMED_01439	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PELLHMED_01440	5.47e-199	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PELLHMED_01441	0.0	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
PELLHMED_01442	1.05e-225	-	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
PELLHMED_01443	8.27e-190	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PELLHMED_01444	2.7e-10	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PELLHMED_01445	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PELLHMED_01446	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PELLHMED_01447	1.11e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PELLHMED_01448	0.0	-	-	-	G	-	-	-	isomerase
PELLHMED_01449	1.41e-286	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PELLHMED_01450	9.9e-240	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
PELLHMED_01451	5.73e-202	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
PELLHMED_01452	2.68e-225	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
PELLHMED_01453	0.0	glpK3	2.7.1.30	-	G	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	FGGY family of carbohydrate kinases, C-terminal domain
PELLHMED_01454	1.12e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PELLHMED_01455	8.07e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PELLHMED_01458	2.37e-210	-	-	-	-	-	-	-	-
PELLHMED_01459	5.77e-214	-	-	-	-	-	-	-	-
PELLHMED_01460	7.72e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01461	7.05e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PELLHMED_01462	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PELLHMED_01463	4.04e-304	ynbB	-	-	P	-	-	-	aluminum resistance
PELLHMED_01464	8.27e-221	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PELLHMED_01465	1.48e-90	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PELLHMED_01466	4.01e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PELLHMED_01467	4.62e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
PELLHMED_01468	3.23e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PELLHMED_01469	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PELLHMED_01470	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PELLHMED_01471	0.0	-	-	-	S	-	-	-	membrane
PELLHMED_01472	2.46e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
PELLHMED_01473	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PELLHMED_01474	1.06e-69	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PELLHMED_01475	3.51e-17	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PELLHMED_01476	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PELLHMED_01477	1.6e-217	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
PELLHMED_01478	3.63e-94	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PELLHMED_01479	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PELLHMED_01480	2.59e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PELLHMED_01481	1.24e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PELLHMED_01482	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PELLHMED_01483	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PELLHMED_01484	1.89e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PELLHMED_01485	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PELLHMED_01486	6.08e-164	csrR	-	-	K	-	-	-	response regulator
PELLHMED_01487	3.14e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PELLHMED_01488	9.35e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PELLHMED_01489	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PELLHMED_01490	4.06e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PELLHMED_01491	8.11e-159	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PELLHMED_01492	4.26e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PELLHMED_01493	1.66e-120	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PELLHMED_01494	4.78e-253	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PELLHMED_01495	8.82e-241	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PELLHMED_01496	4.31e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PELLHMED_01497	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PELLHMED_01498	9.48e-95	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PELLHMED_01499	1.92e-118	-	-	-	-	-	-	-	-
PELLHMED_01500	1.39e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PELLHMED_01501	2.67e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
PELLHMED_01502	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PELLHMED_01503	5.35e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PELLHMED_01504	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
PELLHMED_01505	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PELLHMED_01506	5.52e-139	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PELLHMED_01507	6.72e-205	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PELLHMED_01508	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PELLHMED_01509	0.0	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PELLHMED_01510	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PELLHMED_01511	3.61e-144	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PELLHMED_01512	3.52e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PELLHMED_01513	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PELLHMED_01514	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PELLHMED_01515	1.15e-165	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PELLHMED_01516	1.88e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PELLHMED_01517	1.24e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PELLHMED_01518	1.85e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PELLHMED_01519	7.36e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PELLHMED_01520	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PELLHMED_01521	1.9e-160	-	-	-	C	-	-	-	Flavodoxin
PELLHMED_01522	5.58e-192	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
PELLHMED_01523	2.68e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PELLHMED_01524	2.76e-249	-	-	-	S	-	-	-	Bacteriocin helveticin-J
PELLHMED_01525	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
PELLHMED_01526	2.45e-227	-	-	-	S	-	-	-	SLAP domain
PELLHMED_01527	2.86e-146	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PELLHMED_01528	5.44e-127	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PELLHMED_01529	6.25e-304	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PELLHMED_01530	2.45e-214	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
PELLHMED_01531	1.09e-135	-	-	-	S	-	-	-	Membrane
PELLHMED_01532	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PELLHMED_01533	0.0	-	-	-	G	ko:K02755,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PELLHMED_01534	2.24e-41	-	2.7.1.208, 2.7.1.211	-	G	ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PELLHMED_01535	2.69e-191	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PELLHMED_01536	0.0	-	-	-	-	-	-	-	-
PELLHMED_01537	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PELLHMED_01538	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PELLHMED_01539	5.52e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
PELLHMED_01540	9.15e-165	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PELLHMED_01541	3.37e-273	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PELLHMED_01542	3.15e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01543	1.38e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
PELLHMED_01544	3.51e-74	-	-	-	-	-	-	-	-
PELLHMED_01545	3.26e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PELLHMED_01546	3.19e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
PELLHMED_01547	0.0	yhaN	-	-	L	-	-	-	AAA domain
PELLHMED_01548	8.31e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
PELLHMED_01549	6.93e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PELLHMED_01550	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PELLHMED_01551	3.09e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PELLHMED_01552	1.34e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PELLHMED_01553	2.79e-154	-	-	-	-	-	-	-	-
PELLHMED_01554	2.45e-246	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
PELLHMED_01555	1.48e-217	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PELLHMED_01556	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PELLHMED_01557	1.06e-164	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PELLHMED_01558	3.16e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PELLHMED_01559	3.95e-310	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PELLHMED_01561	1.19e-71	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
PELLHMED_01562	4.1e-251	flp	-	-	V	-	-	-	Beta-lactamase
PELLHMED_01563	3.16e-72	-	-	-	-	-	-	-	-
PELLHMED_01564	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
PELLHMED_01565	4.95e-53	-	-	-	S	-	-	-	Enterocin A Immunity
PELLHMED_01566	0.0	-	-	-	S	-	-	-	domain, Protein
PELLHMED_01567	6.41e-105	-	-	-	S	-	-	-	Cupin domain
PELLHMED_01568	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PELLHMED_01569	1.39e-22	-	-	-	K	-	-	-	transcriptional regulator
PELLHMED_01570	3.3e-94	-	-	-	K	-	-	-	transcriptional regulator
PELLHMED_01572	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PELLHMED_01573	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PELLHMED_01574	7.75e-153	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PELLHMED_01575	7.6e-118	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PELLHMED_01576	1.29e-150	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PELLHMED_01577	1.37e-36	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PELLHMED_01578	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
PELLHMED_01579	5.35e-289	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PELLHMED_01584	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PELLHMED_01585	1.28e-131	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PELLHMED_01586	1.47e-144	-	-	-	S	-	-	-	SNARE associated Golgi protein
PELLHMED_01587	1.84e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PELLHMED_01588	4.92e-207	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PELLHMED_01589	3.62e-121	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
PELLHMED_01590	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PELLHMED_01591	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
PELLHMED_01592	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
PELLHMED_01593	6.9e-220	-	-	-	-	-	-	-	-
PELLHMED_01594	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
PELLHMED_01595	1.8e-124	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PELLHMED_01596	2.62e-198	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PELLHMED_01597	7.19e-202	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PELLHMED_01598	2.47e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PELLHMED_01599	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
PELLHMED_01600	1.68e-188	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PELLHMED_01601	1.24e-197	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
PELLHMED_01602	9.81e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
PELLHMED_01603	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PELLHMED_01604	4.53e-203	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
PELLHMED_01605	4e-234	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
PELLHMED_01606	4.72e-200	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PELLHMED_01607	7.21e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PELLHMED_01608	9.54e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PELLHMED_01609	0.0	-	-	-	M	-	-	-	domain protein
PELLHMED_01610	3.05e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PELLHMED_01611	0.0	-	-	-	-	-	-	-	-
PELLHMED_01612	7.95e-64	-	-	-	-	-	-	-	-
PELLHMED_01613	9.1e-184	-	-	-	S	-	-	-	PAS domain
PELLHMED_01614	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PELLHMED_01615	5.44e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PELLHMED_01616	2.91e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PELLHMED_01617	4.14e-312	-	-	-	T	-	-	-	GHKL domain
PELLHMED_01618	2.36e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PELLHMED_01619	1.34e-131	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PELLHMED_01620	4.9e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
PELLHMED_01621	3.59e-123	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PELLHMED_01622	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PELLHMED_01623	2.28e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PELLHMED_01624	9.2e-130	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PELLHMED_01625	8.57e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PELLHMED_01626	3.51e-221	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PELLHMED_01627	1.68e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PELLHMED_01628	1.25e-106	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PELLHMED_01629	2.71e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PELLHMED_01630	1.29e-140	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PELLHMED_01631	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PELLHMED_01632	2.14e-31	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PELLHMED_01633	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PELLHMED_01634	1.69e-160	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PELLHMED_01635	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
PELLHMED_01636	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PELLHMED_01637	3.02e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01638	7.62e-308	-	-	-	S	-	-	-	response to antibiotic
PELLHMED_01639	1.39e-164	-	-	-	-	-	-	-	-
PELLHMED_01640	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PELLHMED_01641	3.66e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PELLHMED_01642	3.45e-64	-	-	-	-	-	-	-	-
PELLHMED_01643	1.25e-22	-	-	-	-	-	-	-	-
PELLHMED_01644	1.35e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
PELLHMED_01645	7.07e-178	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PELLHMED_01646	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
PELLHMED_01647	8.44e-201	-	-	-	-	-	-	-	-
PELLHMED_01648	1.6e-119	-	-	-	-	-	-	-	-
PELLHMED_01649	3.39e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
PELLHMED_01652	0.0	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
PELLHMED_01653	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
PELLHMED_01654	5.59e-250	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PELLHMED_01655	1.56e-256	-	-	-	S	-	-	-	Membrane
PELLHMED_01656	1.71e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PELLHMED_01657	7.86e-240	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PELLHMED_01658	3.86e-239	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PELLHMED_01659	1.96e-192	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PELLHMED_01660	1.06e-258	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
PELLHMED_01661	1.24e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PELLHMED_01662	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PELLHMED_01663	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PELLHMED_01664	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PELLHMED_01665	4.37e-205	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PELLHMED_01666	0.0	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
PELLHMED_01668	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
PELLHMED_01669	4.05e-119	-	-	-	-	-	-	-	-
PELLHMED_01670	6.91e-235	-	-	-	-	-	-	-	-
PELLHMED_01671	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
PELLHMED_01678	1.31e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PELLHMED_01679	6.89e-280	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PELLHMED_01680	2.52e-84	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PELLHMED_01681	1.63e-175	-	-	-	L	ko:K07483	-	ko00000	transposase activity
PELLHMED_01682	1.34e-298	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PELLHMED_01683	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PELLHMED_01684	7.05e-126	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PELLHMED_01685	1.31e-93	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
PELLHMED_01686	1.86e-287	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
PELLHMED_01687	7.58e-244	XK27_01805	-	-	M	-	-	-	Glycosyltransferase like family 2
PELLHMED_01688	4.69e-158	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PELLHMED_01690	2.65e-215	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
PELLHMED_01691	4.02e-192	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PELLHMED_01692	1.77e-159	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
PELLHMED_01693	6.17e-191	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PELLHMED_01694	5.93e-166	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PELLHMED_01695	1.01e-193	epsB	-	-	M	-	-	-	biosynthesis protein
PELLHMED_01696	5.44e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PELLHMED_01697	1.42e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PELLHMED_01698	5.52e-241	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PELLHMED_01699	0.0	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
PELLHMED_01700	1.4e-204	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PELLHMED_01701	2.99e-176	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PELLHMED_01702	7.09e-125	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PELLHMED_01703	6.94e-110	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
PELLHMED_01704	2.96e-56	-	-	-	-	-	-	-	-
PELLHMED_01705	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
PELLHMED_01706	4.7e-143	-	-	-	-	-	-	-	-
PELLHMED_01707	7.02e-103	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
PELLHMED_01708	2.71e-233	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PELLHMED_01709	1.36e-105	-	-	-	-	-	-	-	-
PELLHMED_01710	3.7e-175	-	-	-	S	-	-	-	Peptidase_C39 like family
PELLHMED_01711	1.47e-70	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PELLHMED_01712	1.08e-62	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PELLHMED_01713	1.64e-47	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PELLHMED_01714	4.44e-110	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PELLHMED_01715	3.8e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
PELLHMED_01716	0.0	-	-	-	S	-	-	-	ABC transporter
PELLHMED_01717	3.08e-81	-	-	-	-	-	-	-	-
PELLHMED_01718	2.7e-59	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PELLHMED_01719	5.01e-293	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PELLHMED_01720	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PELLHMED_01721	9.86e-59	-	-	-	P	ko:K03449	-	ko00000,ko02000	transmembrane transport
PELLHMED_01722	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
PELLHMED_01723	1.04e-82	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PELLHMED_01724	6.99e-174	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PELLHMED_01725	6.65e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PELLHMED_01726	1.79e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PELLHMED_01727	7.83e-60	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PELLHMED_01728	3e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
PELLHMED_01729	4.7e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PELLHMED_01730	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PELLHMED_01731	1.31e-216	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PELLHMED_01732	3.67e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
PELLHMED_01733	5.63e-253	-	-	-	S	-	-	-	Fic/DOC family
PELLHMED_01734	7.39e-276	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PELLHMED_01735	1.6e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01736	2.89e-12	-	-	-	-	-	-	-	-
PELLHMED_01737	4.14e-89	-	-	-	-	-	-	-	-
PELLHMED_01738	6.68e-35	-	-	-	-	-	-	-	-
PELLHMED_01739	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
PELLHMED_01740	9.7e-116	-	-	-	-	-	-	-	-
PELLHMED_01741	2.26e-29	-	-	-	-	-	-	-	-
PELLHMED_01746	1.21e-275	blpT	-	-	-	-	-	-	-
PELLHMED_01747	3.21e-136	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PELLHMED_01748	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PELLHMED_01751	7.63e-190	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PELLHMED_01752	8.09e-298	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PELLHMED_01753	2e-06	-	-	-	-	-	-	-	-
PELLHMED_01756	2.6e-141	-	-	-	-	-	-	-	-
PELLHMED_01758	2.71e-136	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PELLHMED_01759	5.21e-275	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PELLHMED_01760	2.62e-50	-	-	-	S	-	-	-	Enterocin A Immunity
PELLHMED_01761	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
PELLHMED_01762	9.17e-37	-	-	-	-	-	-	-	-
PELLHMED_01763	1.47e-45	-	-	-	-	-	-	-	-
PELLHMED_01764	1.4e-69	-	-	-	S	-	-	-	Enterocin A Immunity
PELLHMED_01765	5.63e-64	-	-	-	S	-	-	-	Enterocin A Immunity
PELLHMED_01766	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PELLHMED_01767	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PELLHMED_01768	9.58e-267	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
PELLHMED_01769	1.44e-157	vanR	-	-	K	-	-	-	response regulator
PELLHMED_01770	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PELLHMED_01771	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01772	1.55e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PELLHMED_01773	1.39e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PELLHMED_01774	2.22e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PELLHMED_01775	2.05e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PELLHMED_01776	4.1e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PELLHMED_01777	2.79e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PELLHMED_01778	3.14e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PELLHMED_01779	8.5e-105	cvpA	-	-	S	-	-	-	Colicin V production protein
PELLHMED_01780	6.64e-233	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PELLHMED_01781	9.1e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PELLHMED_01782	6.34e-127	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PELLHMED_01783	4.14e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PELLHMED_01784	2.15e-144	-	-	-	K	-	-	-	WHG domain
PELLHMED_01785	2e-26	-	-	-	-	-	-	-	-
PELLHMED_01786	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PELLHMED_01787	3.26e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01788	1.43e-231	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PELLHMED_01789	1.45e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PELLHMED_01790	9.98e-146	-	-	-	G	-	-	-	phosphoglycerate mutase
PELLHMED_01791	1.19e-179	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
PELLHMED_01792	4.33e-185	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PELLHMED_01793	3.44e-153	-	-	-	-	-	-	-	-
PELLHMED_01794	3.08e-204	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PELLHMED_01795	1.71e-282	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PELLHMED_01796	2.13e-36	-	-	-	-	-	-	-	-
PELLHMED_01797	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PELLHMED_01798	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PELLHMED_01799	7.67e-80	lysM	-	-	M	-	-	-	LysM domain
PELLHMED_01800	9.68e-226	-	-	-	-	-	-	-	-
PELLHMED_01801	3e-133	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PELLHMED_01802	8.59e-148	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PELLHMED_01804	1.97e-280	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
PELLHMED_01805	1.53e-118	ymdB	-	-	S	-	-	-	Macro domain protein
PELLHMED_01806	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
PELLHMED_01809	2.49e-189	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PELLHMED_01810	2.56e-110	-	-	-	-	-	-	-	-
PELLHMED_01811	8.05e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PELLHMED_01812	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PELLHMED_01813	1.35e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PELLHMED_01814	6e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PELLHMED_01815	0.0	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PELLHMED_01816	1.23e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PELLHMED_01817	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PELLHMED_01818	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PELLHMED_01819	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
PELLHMED_01820	1.82e-276	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PELLHMED_01821	7.43e-229	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PELLHMED_01822	7.79e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PELLHMED_01823	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PELLHMED_01824	4.8e-99	-	-	-	-	-	-	-	-
PELLHMED_01825	1.06e-20	-	-	-	-	-	-	-	-
PELLHMED_01826	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PELLHMED_01827	6.65e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PELLHMED_01828	1.23e-83	-	-	-	S	-	-	-	Protein conserved in bacteria
PELLHMED_01829	9.67e-220	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PELLHMED_01830	1.91e-171	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
PELLHMED_01831	1.96e-108	-	-	-	M	-	-	-	NlpC/P60 family
PELLHMED_01832	8.16e-212	-	-	-	EG	-	-	-	EamA-like transporter family
PELLHMED_01833	1.03e-211	-	-	-	EG	-	-	-	EamA-like transporter family
PELLHMED_01834	1.41e-209	yicL	-	-	EG	-	-	-	EamA-like transporter family
PELLHMED_01835	7.08e-137	-	-	-	-	-	-	-	-
PELLHMED_01836	6.33e-74	-	-	-	-	-	-	-	-
PELLHMED_01837	1.14e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PELLHMED_01838	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PELLHMED_01839	2.84e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PELLHMED_01842	1.69e-259	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
PELLHMED_01843	4.6e-249	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PELLHMED_01844	6.65e-153	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
PELLHMED_01845	1.23e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PELLHMED_01846	6.09e-152	-	-	-	K	-	-	-	Rhodanese Homology Domain
PELLHMED_01847	1.75e-10	-	-	-	-	-	-	-	-
PELLHMED_01848	1.27e-70	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
PELLHMED_01849	1e-305	-	-	-	E	-	-	-	amino acid
PELLHMED_01850	1.4e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PELLHMED_01851	1.84e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PELLHMED_01852	4.27e-293	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PELLHMED_01853	8.71e-157	-	-	-	-	-	-	-	-
PELLHMED_01854	0.0	-	-	-	L	-	-	-	Transposase
PELLHMED_01855	1.07e-150	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PELLHMED_01856	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
PELLHMED_01857	4.24e-217	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PELLHMED_01858	1e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PELLHMED_01859	8.01e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01860	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PELLHMED_01861	5.63e-49	-	-	-	-	-	-	-	-
PELLHMED_01862	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PELLHMED_01863	9.26e-222	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PELLHMED_01864	9.09e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PELLHMED_01865	3.45e-79	-	-	-	-	-	-	-	-
PELLHMED_01866	3.4e-228	pbpX2	-	-	V	-	-	-	Beta-lactamase
PELLHMED_01867	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PELLHMED_01868	2.46e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PELLHMED_01869	3.35e-310	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PELLHMED_01870	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PELLHMED_01871	2.17e-25	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PELLHMED_01872	2.18e-53	-	-	-	-	-	-	-	-
PELLHMED_01873	8.03e-278	-	-	-	S	-	-	-	Membrane
PELLHMED_01874	1.97e-107	ykuL	-	-	S	-	-	-	(CBS) domain
PELLHMED_01875	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PELLHMED_01876	4.69e-262	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
PELLHMED_01877	2.82e-105	-	-	-	S	-	-	-	Putative adhesin
PELLHMED_01878	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PELLHMED_01879	1.57e-197	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PELLHMED_01880	5.7e-125	-	-	-	M	-	-	-	CHAP domain
PELLHMED_01881	1.4e-88	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PELLHMED_01882	2.41e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PELLHMED_01883	3.39e-253	-	-	-	S	-	-	-	DUF218 domain
PELLHMED_01884	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PELLHMED_01885	4.51e-134	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PELLHMED_01886	1.21e-236	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
PELLHMED_01887	9.41e-257	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
PELLHMED_01888	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PELLHMED_01889	9.19e-266	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PELLHMED_01890	4.74e-217	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PELLHMED_01891	1.25e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
PELLHMED_01892	1.19e-175	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PELLHMED_01893	1.63e-152	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PELLHMED_01894	6.91e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PELLHMED_01895	3.03e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PELLHMED_01896	3.53e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PELLHMED_01897	0.0	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PELLHMED_01898	2.29e-166	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PELLHMED_01899	4.08e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PELLHMED_01900	3.14e-226	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PELLHMED_01901	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PELLHMED_01902	8.03e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PELLHMED_01903	2.47e-32	-	-	-	-	-	-	-	-
PELLHMED_01904	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PELLHMED_01905	6.78e-100	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
PELLHMED_01906	1.77e-85	-	-	-	S	-	-	-	Cupredoxin-like domain
PELLHMED_01907	1.09e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
PELLHMED_01908	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PELLHMED_01909	2.91e-234	-	-	-	S	-	-	-	DUF218 domain
PELLHMED_01910	6.11e-168	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
PELLHMED_01911	6.65e-153	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
PELLHMED_01912	1.78e-26	-	-	-	-	-	-	-	-
PELLHMED_01913	5.17e-273	-	-	-	-	-	-	-	-
PELLHMED_01914	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PELLHMED_01915	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PELLHMED_01916	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PELLHMED_01917	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PELLHMED_01918	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PELLHMED_01919	2.31e-199	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PELLHMED_01920	1.87e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PELLHMED_01921	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family