ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MDIBLFOF_00001 1.7e-185 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
MDIBLFOF_00002 2.67e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
MDIBLFOF_00003 1.12e-109 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDIBLFOF_00004 6.62e-185 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
MDIBLFOF_00005 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
MDIBLFOF_00006 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
MDIBLFOF_00007 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
MDIBLFOF_00008 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MDIBLFOF_00010 2.19e-223 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDIBLFOF_00011 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
MDIBLFOF_00012 3.03e-197 - - - - - - - -
MDIBLFOF_00013 5.01e-228 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MDIBLFOF_00014 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDIBLFOF_00015 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
MDIBLFOF_00016 1.89e-133 - - - L - - - Helix-turn-helix domain
MDIBLFOF_00017 1.54e-269 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDIBLFOF_00018 1.54e-220 - - - K - - - Psort location Cytoplasmic, score
MDIBLFOF_00019 0.0 - - - KLT - - - Protein tyrosine kinase
MDIBLFOF_00020 1.29e-201 - - - O - - - Thioredoxin
MDIBLFOF_00022 1.28e-278 rpfB - - S ko:K21688 - ko00000 G5
MDIBLFOF_00023 8.92e-218 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDIBLFOF_00024 2.78e-215 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDIBLFOF_00025 6.94e-146 - - - S - - - LytR cell envelope-related transcriptional attenuator
MDIBLFOF_00026 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
MDIBLFOF_00027 3.18e-160 mutT4 - - L - - - Belongs to the Nudix hydrolase family
MDIBLFOF_00028 0.0 - - - M - - - Conserved repeat domain
MDIBLFOF_00029 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
MDIBLFOF_00030 1.13e-257 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDIBLFOF_00031 1.7e-313 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MDIBLFOF_00032 3.68e-230 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MDIBLFOF_00033 4.29e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MDIBLFOF_00034 4.15e-120 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
MDIBLFOF_00035 2.11e-227 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
MDIBLFOF_00036 3.88e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MDIBLFOF_00037 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDIBLFOF_00038 1.15e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDIBLFOF_00039 1.44e-310 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDIBLFOF_00040 1.36e-125 - - - S - - - Protein of unknown function (DUF721)
MDIBLFOF_00041 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDIBLFOF_00042 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDIBLFOF_00043 4.11e-104 - - - S - - - Transmembrane domain of unknown function (DUF3566)
MDIBLFOF_00046 1.02e-238 - - - G - - - Glycosyl hydrolases family 43
MDIBLFOF_00047 1.09e-238 - - - K - - - Periplasmic binding protein domain
MDIBLFOF_00048 4.38e-289 - - - I - - - Serine aminopeptidase, S33
MDIBLFOF_00049 9.05e-12 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDIBLFOF_00050 2.87e-56 - - - S - - - Protein of unknown function (DUF2442)
MDIBLFOF_00051 2.86e-145 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MDIBLFOF_00052 0.0 - 2.1.1.72 - L ko:K07317 - ko00000,ko01000,ko02048 Eco57I restriction-modification methylase
MDIBLFOF_00053 7.78e-235 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 BsuBI/PstI restriction endonuclease C-terminus
MDIBLFOF_00054 1.49e-290 - - - - - - - -
MDIBLFOF_00056 2.82e-236 - - - L - - - Phage integrase family
MDIBLFOF_00057 1.52e-07 - - - M - - - PA domain
MDIBLFOF_00058 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MDIBLFOF_00059 3.5e-162 gntR - - K - - - FCD
MDIBLFOF_00060 9.15e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDIBLFOF_00061 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
MDIBLFOF_00062 9.19e-124 - - - KT - - - MT-A70
MDIBLFOF_00063 6.41e-102 - - - L - - - Restriction endonuclease BglII
MDIBLFOF_00064 1.51e-79 - - - - - - - -
MDIBLFOF_00065 9.21e-27 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
MDIBLFOF_00069 1.21e-122 - - - L - - - Phage integrase family
MDIBLFOF_00072 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
MDIBLFOF_00073 3.09e-245 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDIBLFOF_00074 6.23e-102 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDIBLFOF_00075 1.49e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MDIBLFOF_00076 0.0 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MDIBLFOF_00077 1.84e-169 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
MDIBLFOF_00078 2.68e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MDIBLFOF_00079 1.34e-238 - - - EG - - - EamA-like transporter family
MDIBLFOF_00080 1.37e-305 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
MDIBLFOF_00081 2.12e-125 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDIBLFOF_00082 1.05e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MDIBLFOF_00083 1.01e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
MDIBLFOF_00084 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
MDIBLFOF_00085 2.27e-307 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MDIBLFOF_00086 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MDIBLFOF_00087 0.0 - - - S - - - Threonine/Serine exporter, ThrE
MDIBLFOF_00088 7.63e-228 - - - S - - - Amidohydrolase family
MDIBLFOF_00089 1.67e-248 - - - S - - - Protein conserved in bacteria
MDIBLFOF_00090 1.2e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MDIBLFOF_00091 5.42e-67 - - - S - - - Protein of unknown function (DUF3073)
MDIBLFOF_00092 2.26e-143 - - - T - - - protein histidine kinase activity
MDIBLFOF_00093 5.04e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDIBLFOF_00094 1.44e-33 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MDIBLFOF_00095 0.0 - - - M - - - Glycosyl hydrolases family 25
MDIBLFOF_00096 3.57e-235 - - GT2 M ko:K13670 - ko00000,ko01000 Glycosyltransferase like family 2
MDIBLFOF_00097 3.77e-177 tnp3521a2 - - L - - - Integrase core domain
MDIBLFOF_00098 6.79e-68 - - - L ko:K07483 - ko00000 Transposase
MDIBLFOF_00099 2.82e-162 istB - - L - - - IstB-like ATP binding protein
MDIBLFOF_00100 1.96e-158 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00101 2.46e-153 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00102 3.24e-57 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00103 2.28e-57 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00104 0.0 - - - S - - - Glucosyl transferase GtrII
MDIBLFOF_00105 0.0 - - - S - - - Polysaccharide pyruvyl transferase
MDIBLFOF_00106 0.0 - - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
MDIBLFOF_00107 2.1e-246 - - - I - - - Acyltransferase family
MDIBLFOF_00108 1.44e-92 - 1.1.1.339 - GM ko:K19180 ko00523,ko01130,map00523,map01130 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MDIBLFOF_00109 5.35e-107 - - - L ko:K07483,ko:K07497 - ko00000 transposase activity
MDIBLFOF_00110 2.34e-152 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00111 3.6e-206 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00112 0.0 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00113 3.27e-184 istB - - L - - - IstB-like ATP binding protein
MDIBLFOF_00114 1.02e-194 istB - - L - - - IstB-like ATP binding protein
MDIBLFOF_00115 2.98e-130 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00116 6.8e-250 - - - M - - - Glycosyltransferase like family 2
MDIBLFOF_00117 1.79e-138 - - - - - - - -
MDIBLFOF_00118 1.31e-57 tnp3521a2 - - L - - - Integrase core domain
MDIBLFOF_00119 9.11e-69 tnp3521a2 - - L - - - Integrase core domain
MDIBLFOF_00120 3.19e-74 - - - L ko:K07483 - ko00000 transposase activity
MDIBLFOF_00121 1.1e-31 - - - - - - - -
MDIBLFOF_00122 2.49e-14 - - - L ko:K07485 - ko00000 Transposase
MDIBLFOF_00123 1.9e-51 - - - L - - - Transposase
MDIBLFOF_00124 9.29e-220 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDIBLFOF_00125 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDIBLFOF_00126 3.56e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDIBLFOF_00127 2.32e-197 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
MDIBLFOF_00128 1.21e-306 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_00129 1.9e-120 - - - L - - - Transposase and inactivated derivatives IS30 family
MDIBLFOF_00130 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
MDIBLFOF_00131 1.53e-24 yccF - - S - - - Inner membrane component domain
MDIBLFOF_00132 1.9e-17 - - - - - - - -
MDIBLFOF_00133 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
MDIBLFOF_00134 7.04e-57 - - - L - - - Integrase core domain
MDIBLFOF_00135 4.03e-56 istB - - L - - - IstB-like ATP binding protein
MDIBLFOF_00136 6.2e-56 - - - L ko:K07485 - ko00000 Transposase
MDIBLFOF_00137 2.31e-45 - - - V ko:K06147 - ko00000,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_00138 5.53e-96 - - - I - - - Sterol carrier protein
MDIBLFOF_00139 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MDIBLFOF_00140 7.68e-47 - - - - - - - -
MDIBLFOF_00141 3.41e-186 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
MDIBLFOF_00142 2.54e-149 - - - L - - - HTH-like domain
MDIBLFOF_00143 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
MDIBLFOF_00144 3.28e-99 crgA - - D - - - Involved in cell division
MDIBLFOF_00145 1.18e-182 - - - S - - - Bacterial protein of unknown function (DUF881)
MDIBLFOF_00146 2.3e-295 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MDIBLFOF_00147 9.5e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
MDIBLFOF_00148 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MDIBLFOF_00149 5.69e-234 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MDIBLFOF_00150 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MDIBLFOF_00151 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MDIBLFOF_00152 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
MDIBLFOF_00153 1.68e-121 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
MDIBLFOF_00154 3.69e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
MDIBLFOF_00155 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
MDIBLFOF_00156 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
MDIBLFOF_00157 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
MDIBLFOF_00158 3.44e-263 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
MDIBLFOF_00159 1.31e-214 - - - EG - - - EamA-like transporter family
MDIBLFOF_00160 8.17e-148 - - - - - - - -
MDIBLFOF_00162 1.17e-250 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDIBLFOF_00164 0.0 - - - KL - - - Domain of unknown function (DUF3427)
MDIBLFOF_00165 9.44e-116 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MDIBLFOF_00166 1.01e-63 - - - D - - - DivIVA domain protein
MDIBLFOF_00167 3.02e-70 - - - S - - - Putative heavy-metal-binding
MDIBLFOF_00168 2.16e-199 - - - I - - - Serine aminopeptidase, S33
MDIBLFOF_00169 3.17e-110 - - - Q - - - Acetyltransferase (GNAT) domain
MDIBLFOF_00171 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDIBLFOF_00172 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
MDIBLFOF_00173 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
MDIBLFOF_00174 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
MDIBLFOF_00175 1.95e-222 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MDIBLFOF_00177 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MDIBLFOF_00178 1.23e-55 - - - S - - - Bacterial mobilisation protein (MobC)
MDIBLFOF_00179 3.76e-163 - - - S - - - Domain of unknown function (DUF4417)
MDIBLFOF_00181 4.37e-80 - - - - - - - -
MDIBLFOF_00182 4.81e-84 - - - - - - - -
MDIBLFOF_00183 7.82e-65 - - - E - - - IrrE N-terminal-like domain
MDIBLFOF_00185 1.42e-74 - - - K - - - Cro/C1-type HTH DNA-binding domain
MDIBLFOF_00186 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MDIBLFOF_00187 1.25e-252 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MDIBLFOF_00188 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDIBLFOF_00189 3.06e-211 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDIBLFOF_00190 3.43e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDIBLFOF_00191 4.68e-256 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDIBLFOF_00192 1.96e-102 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
MDIBLFOF_00193 0.0 scrT - - G - - - Transporter major facilitator family protein
MDIBLFOF_00194 0.0 - - - EGP - - - Sugar (and other) transporter
MDIBLFOF_00195 6.15e-261 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MDIBLFOF_00196 7.18e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MDIBLFOF_00197 1.15e-234 - - - S - - - Protein of unknown function (DUF559)
MDIBLFOF_00198 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MDIBLFOF_00199 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
MDIBLFOF_00200 2.46e-132 - - - K - - - Transcriptional regulator C-terminal region
MDIBLFOF_00201 4.31e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MDIBLFOF_00202 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MDIBLFOF_00203 2.21e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDIBLFOF_00204 5.48e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDIBLFOF_00205 3.79e-52 urtE - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDIBLFOF_00206 6.82e-128 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
MDIBLFOF_00207 5.54e-202 - - - S ko:K07058 - ko00000 Virulence factor BrkB
MDIBLFOF_00208 7.13e-56 - - - O - - - Glutaredoxin
MDIBLFOF_00209 2.19e-135 - - - L ko:K07485 - ko00000 Transposase
MDIBLFOF_00210 0.0 - - - S - - - Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MDIBLFOF_00211 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MDIBLFOF_00212 1.81e-50 - - - L ko:K07454 - ko00000 HNH endonuclease
MDIBLFOF_00213 5.38e-306 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MDIBLFOF_00215 0.0 - - - EGP - - - Major Facilitator Superfamily
MDIBLFOF_00216 1.57e-54 - - - IQ - - - [acyl-carrier-protein] S-malonyltransferase activity
MDIBLFOF_00217 3.51e-58 - - - L ko:K07483 - ko00000 Integrase core domain
MDIBLFOF_00218 1.48e-50 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
MDIBLFOF_00219 1.11e-148 - - - K - - - WHG domain
MDIBLFOF_00220 0.0 - - - L - - - PFAM Integrase catalytic
MDIBLFOF_00221 1.97e-184 istB - - L - - - IstB-like ATP binding protein
MDIBLFOF_00222 1.55e-115 - - - Q - - - 4'-phosphopantetheinyl transferase superfamily
MDIBLFOF_00223 2.72e-20 - - - - - - - -
MDIBLFOF_00224 0.0 - - - - - - - -
MDIBLFOF_00225 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
MDIBLFOF_00227 2.77e-169 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MDIBLFOF_00228 2.4e-230 - - - V - - - Abi-like protein
MDIBLFOF_00229 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MDIBLFOF_00230 4.68e-78 - - - S - - - Bacterial mobilisation protein (MobC)
MDIBLFOF_00231 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
MDIBLFOF_00232 6.29e-135 - - - - - - - -
MDIBLFOF_00235 0.0 intA - - L - - - Phage integrase, N-terminal SAM-like domain
MDIBLFOF_00237 4.45e-21 - - - - - - - -
MDIBLFOF_00238 2.97e-127 - - - M - - - Belongs to the glycosyl hydrolase 30 family
MDIBLFOF_00239 1.81e-243 - - - C - - - Aldo/keto reductase family
MDIBLFOF_00240 1.9e-56 - - - S - - - Protein of unknown function (DUF1778)
MDIBLFOF_00241 3.56e-121 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDIBLFOF_00242 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_00243 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
MDIBLFOF_00244 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
MDIBLFOF_00245 3.03e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MDIBLFOF_00246 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
MDIBLFOF_00247 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
MDIBLFOF_00248 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
MDIBLFOF_00249 6.15e-127 - - - S - - - GtrA-like protein
MDIBLFOF_00250 0.0 - - - EGP - - - Major Facilitator Superfamily
MDIBLFOF_00251 4.52e-161 - - - G - - - Phosphoglycerate mutase family
MDIBLFOF_00252 2.32e-193 - - - - - - - -
MDIBLFOF_00253 4.1e-178 - - - P - - - Binding-protein-dependent transport system inner membrane component
MDIBLFOF_00254 5.05e-258 - - - P - - - NMT1/THI5 like
MDIBLFOF_00255 1.65e-159 - - - S - - - HAD hydrolase, family IA, variant 3
MDIBLFOF_00257 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDIBLFOF_00258 4.57e-69 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
MDIBLFOF_00259 9.29e-86 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
MDIBLFOF_00262 3.88e-316 - - - S - - - Calcineurin-like phosphoesterase
MDIBLFOF_00263 1.59e-179 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
MDIBLFOF_00264 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDIBLFOF_00265 3.31e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDIBLFOF_00266 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
MDIBLFOF_00268 2.26e-247 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDIBLFOF_00269 1.51e-280 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
MDIBLFOF_00270 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDIBLFOF_00271 1.08e-290 - - - G - - - Transmembrane secretion effector
MDIBLFOF_00272 1.69e-169 - - - K - - - Bacterial regulatory proteins, tetR family
MDIBLFOF_00273 3.36e-184 - - - - - - - -
MDIBLFOF_00274 1.43e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDIBLFOF_00275 1.23e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDIBLFOF_00276 4.41e-223 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
MDIBLFOF_00277 1.99e-240 - - - - - - - -
MDIBLFOF_00278 3.4e-231 - - - - - - - -
MDIBLFOF_00279 2.52e-214 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
MDIBLFOF_00280 9.54e-153 - - - S - - - CYTH
MDIBLFOF_00283 2.41e-236 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
MDIBLFOF_00284 3.13e-39 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
MDIBLFOF_00285 9.13e-195 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
MDIBLFOF_00287 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
MDIBLFOF_00288 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
MDIBLFOF_00289 1.6e-229 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MDIBLFOF_00290 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MDIBLFOF_00291 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDIBLFOF_00292 5.94e-107 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MDIBLFOF_00293 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MDIBLFOF_00294 1.79e-304 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
MDIBLFOF_00295 1.58e-238 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDIBLFOF_00296 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
MDIBLFOF_00297 8.1e-87 - - - - - - - -
MDIBLFOF_00298 8.09e-76 - - - - - - - -
MDIBLFOF_00299 1.85e-209 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_00300 0.0 - - - V - - - Efflux ABC transporter, permease protein
MDIBLFOF_00301 5.52e-214 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MDIBLFOF_00302 2e-304 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MDIBLFOF_00303 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
MDIBLFOF_00304 1.44e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MDIBLFOF_00305 2.12e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
MDIBLFOF_00306 6.56e-276 - - - K - - - Psort location Cytoplasmic, score
MDIBLFOF_00307 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDIBLFOF_00308 2.13e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDIBLFOF_00309 7.11e-295 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
MDIBLFOF_00311 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDIBLFOF_00312 5.02e-161 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MDIBLFOF_00313 1.27e-221 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
MDIBLFOF_00314 1.38e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MDIBLFOF_00315 1.42e-278 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MDIBLFOF_00316 1.28e-254 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MDIBLFOF_00317 0.0 - 3.2.1.97 GH101 G ko:K17624 - ko00000,ko01000 Glycosyl hydrolase 101 beta sandwich domain
MDIBLFOF_00318 5.34e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDIBLFOF_00319 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MDIBLFOF_00320 5.79e-167 - - - - - - - -
MDIBLFOF_00321 2.92e-221 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
MDIBLFOF_00322 6.47e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MDIBLFOF_00323 2.38e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MDIBLFOF_00324 1.51e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDIBLFOF_00325 2.34e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MDIBLFOF_00326 2.59e-41 - - - S - - - Parallel beta-helix repeats
MDIBLFOF_00327 7.2e-95 - - - E - - - Domain of unknown function (DUF5011)
MDIBLFOF_00329 3.99e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MDIBLFOF_00330 1.34e-176 - - - M - - - Protein of unknown function (DUF3152)
MDIBLFOF_00331 8.22e-236 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MDIBLFOF_00332 1.01e-189 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MDIBLFOF_00333 2.45e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
MDIBLFOF_00334 0.0 - - - M - - - domain protein
MDIBLFOF_00335 0.0 - - - M - - - LPXTG cell wall anchor motif
MDIBLFOF_00336 3.09e-269 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MDIBLFOF_00337 4.89e-195 - - - S - - - Domain of unknown function (DUF4854)
MDIBLFOF_00338 2.84e-199 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
MDIBLFOF_00340 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDIBLFOF_00341 1.47e-169 - - - M - - - Mechanosensitive ion channel
MDIBLFOF_00342 3.05e-153 - - - K - - - Bacterial regulatory proteins, tetR family
MDIBLFOF_00343 3.21e-305 - - - S - - - Psort location Cytoplasmic, score 8.87
MDIBLFOF_00344 2.9e-296 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
MDIBLFOF_00345 1.07e-106 - - - M - - - Belongs to the glycosyl hydrolase 28 family
MDIBLFOF_00347 2.91e-40 - - - K - - - Transcriptional regulator
MDIBLFOF_00349 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
MDIBLFOF_00355 3.25e-164 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
MDIBLFOF_00356 2.07e-301 - - - K - - - Helix-turn-helix XRE-family like proteins
MDIBLFOF_00357 1.77e-72 - - - L - - - RelB antitoxin
MDIBLFOF_00359 8.3e-171 - - - K - - - helix_turn_helix, mercury resistance
MDIBLFOF_00360 1.05e-309 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
MDIBLFOF_00363 2.69e-256 - - - G - - - pfkB family carbohydrate kinase
MDIBLFOF_00364 7.42e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
MDIBLFOF_00365 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
MDIBLFOF_00366 1.43e-277 steT - - E ko:K03294 - ko00000 amino acid
MDIBLFOF_00369 0.0 - - - - - - - -
MDIBLFOF_00370 0.0 - - - U ko:K06956 - ko00000 Sodium:dicarboxylate symporter family
MDIBLFOF_00371 3.62e-154 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
MDIBLFOF_00372 7.85e-139 - - - S ko:K07078 - ko00000 Nitroreductase family
MDIBLFOF_00373 9.18e-109 - - - O - - - Hsp20/alpha crystallin family
MDIBLFOF_00374 7.19e-235 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MDIBLFOF_00375 2.27e-139 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDIBLFOF_00376 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MDIBLFOF_00377 2.4e-80 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MDIBLFOF_00378 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
MDIBLFOF_00379 3.89e-131 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
MDIBLFOF_00380 1.35e-282 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MDIBLFOF_00381 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDIBLFOF_00382 2.09e-212 - - - P - - - Cation efflux family
MDIBLFOF_00383 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MDIBLFOF_00384 8.06e-175 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
MDIBLFOF_00385 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
MDIBLFOF_00386 1.04e-76 - - - S - - - Protein of unknown function (DUF3039)
MDIBLFOF_00387 4.42e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDIBLFOF_00388 1.05e-184 - - - - - - - -
MDIBLFOF_00389 2.17e-147 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MDIBLFOF_00390 2.72e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MDIBLFOF_00391 1.56e-179 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDIBLFOF_00392 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
MDIBLFOF_00393 1.26e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
MDIBLFOF_00395 2.46e-315 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDIBLFOF_00396 2.72e-172 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MDIBLFOF_00397 3.26e-151 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDIBLFOF_00398 6.55e-227 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
MDIBLFOF_00401 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MDIBLFOF_00403 2.09e-272 - - - - - - - -
MDIBLFOF_00405 6.19e-263 - - - - - - - -
MDIBLFOF_00407 2.62e-157 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
MDIBLFOF_00408 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
MDIBLFOF_00409 3.47e-28 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
MDIBLFOF_00410 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_00411 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_00412 8.57e-222 - - - K - - - Putative sugar-binding domain
MDIBLFOF_00413 1.46e-283 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MDIBLFOF_00414 0.0 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MDIBLFOF_00415 1.48e-218 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
MDIBLFOF_00416 8.39e-167 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
MDIBLFOF_00417 2.33e-81 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDIBLFOF_00418 6.96e-200 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MDIBLFOF_00419 6.64e-170 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDIBLFOF_00420 2.54e-266 - - - K - - - helix_turn _helix lactose operon repressor
MDIBLFOF_00422 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
MDIBLFOF_00423 8.26e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MDIBLFOF_00424 2.33e-143 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MDIBLFOF_00427 0.0 - - - G - - - Glycosyl hydrolases family 43
MDIBLFOF_00428 2.41e-259 - - - K - - - helix_turn _helix lactose operon repressor
MDIBLFOF_00429 4.25e-217 - - - S - - - Oxidoreductase, aldo keto reductase family protein
MDIBLFOF_00430 8.53e-158 - - - L - - - Protein of unknown function (DUF1524)
MDIBLFOF_00431 1.14e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MDIBLFOF_00432 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
MDIBLFOF_00433 0.0 - - - - - - - -
MDIBLFOF_00434 2.49e-230 - - - S ko:K21688 - ko00000 G5
MDIBLFOF_00435 2.57e-78 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
MDIBLFOF_00436 8.16e-154 - - - F - - - Domain of unknown function (DUF4916)
MDIBLFOF_00437 1.2e-204 - - - I - - - Alpha/beta hydrolase family
MDIBLFOF_00439 0.0 - - - S - - - L,D-transpeptidase catalytic domain
MDIBLFOF_00440 2.17e-93 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MDIBLFOF_00441 0.0 - - - S - - - Uncharacterized conserved protein (DUF2183)
MDIBLFOF_00442 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
MDIBLFOF_00443 4.22e-244 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MDIBLFOF_00444 8.97e-151 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
MDIBLFOF_00445 4.67e-173 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MDIBLFOF_00446 0.0 pon1 - - M - - - Transglycosylase
MDIBLFOF_00447 1.5e-277 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
MDIBLFOF_00448 4.9e-288 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MDIBLFOF_00449 1.2e-179 - - - K - - - DeoR C terminal sensor domain
MDIBLFOF_00450 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
MDIBLFOF_00451 2.4e-296 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
MDIBLFOF_00452 1.32e-308 - - - EGP - - - Sugar (and other) transporter
MDIBLFOF_00453 3.23e-58 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MDIBLFOF_00454 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
MDIBLFOF_00455 2.18e-139 - - - - - - - -
MDIBLFOF_00458 9.1e-157 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDIBLFOF_00459 7.7e-77 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
MDIBLFOF_00460 6.04e-39 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G ko:K01186,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 xyloglucan:xyloglucosyl transferase activity
MDIBLFOF_00461 6.1e-234 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
MDIBLFOF_00462 3.75e-142 - - - - - - - -
MDIBLFOF_00463 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDIBLFOF_00464 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDIBLFOF_00465 6.53e-125 - - - T - - - Forkhead associated domain
MDIBLFOF_00466 5.65e-101 - - - B - - - Belongs to the OprB family
MDIBLFOF_00467 1.65e-211 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
MDIBLFOF_00468 0.0 - - - E - - - Transglutaminase-like superfamily
MDIBLFOF_00469 4.52e-299 - - - S - - - Protein of unknown function DUF58
MDIBLFOF_00470 0.0 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
MDIBLFOF_00471 0.0 - - - S - - - Fibronectin type 3 domain
MDIBLFOF_00472 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MDIBLFOF_00473 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
MDIBLFOF_00474 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
MDIBLFOF_00475 5.54e-210 - - - K - - - -acetyltransferase
MDIBLFOF_00476 0.0 - - - G - - - Major Facilitator Superfamily
MDIBLFOF_00477 8.15e-23 - - - P ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDIBLFOF_00478 3.22e-33 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MDIBLFOF_00479 1.25e-78 - - - L - - - Transposase
MDIBLFOF_00480 1.16e-169 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDIBLFOF_00481 5.72e-207 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDIBLFOF_00482 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDIBLFOF_00483 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
MDIBLFOF_00484 4.07e-85 vpr - - O - - - Subtilase family
MDIBLFOF_00485 1.15e-210 vpr - - O - - - Subtilase family
MDIBLFOF_00486 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDIBLFOF_00487 6.43e-160 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDIBLFOF_00488 0.0 - - - S - - - zinc finger
MDIBLFOF_00489 2.43e-129 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MDIBLFOF_00490 7.65e-293 aspB 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class-V
MDIBLFOF_00491 2.21e-47 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
MDIBLFOF_00492 4.8e-171 tmp1 - - S - - - Domain of unknown function (DUF4391)
MDIBLFOF_00493 8.74e-193 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
MDIBLFOF_00494 0.0 - - - OP - - - Sulfurtransferase TusA
MDIBLFOF_00495 1.92e-233 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MDIBLFOF_00497 3.47e-218 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
MDIBLFOF_00498 5.97e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDIBLFOF_00499 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDIBLFOF_00500 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
MDIBLFOF_00501 1.69e-178 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDIBLFOF_00503 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
MDIBLFOF_00504 2.52e-209 - - - - - - - -
MDIBLFOF_00505 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
MDIBLFOF_00510 9.57e-67 - - - M - - - Parallel beta-helix repeats
MDIBLFOF_00512 3.51e-115 - - - K - - - MarR family
MDIBLFOF_00513 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_00514 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
MDIBLFOF_00515 2.16e-218 - - - S - - - Patatin-like phospholipase
MDIBLFOF_00516 3.31e-197 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MDIBLFOF_00517 6.27e-217 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MDIBLFOF_00518 2.91e-148 - - - S - - - Vitamin K epoxide reductase
MDIBLFOF_00519 3.62e-213 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
MDIBLFOF_00520 1.32e-43 - - - S - - - Protein of unknown function (DUF3107)
MDIBLFOF_00521 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
MDIBLFOF_00522 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDIBLFOF_00523 0.0 - - - S - - - Zincin-like metallopeptidase
MDIBLFOF_00524 2.91e-193 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MDIBLFOF_00525 2.24e-86 - - - S - - - Protein of unknown function (DUF3052)
MDIBLFOF_00526 4.8e-249 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDIBLFOF_00527 1.25e-80 - - - S - - - Thiamine-binding protein
MDIBLFOF_00528 2.08e-210 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MDIBLFOF_00529 3.43e-291 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
MDIBLFOF_00530 1.62e-110 - - - - - - - -
MDIBLFOF_00531 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MDIBLFOF_00532 1.5e-203 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDIBLFOF_00533 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
MDIBLFOF_00534 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
MDIBLFOF_00535 4.69e-314 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDIBLFOF_00536 8.03e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDIBLFOF_00537 9.4e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDIBLFOF_00538 1.35e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
MDIBLFOF_00539 1.65e-191 - - - V - - - DivIVA protein
MDIBLFOF_00540 4.6e-148 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDIBLFOF_00541 2.3e-226 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MDIBLFOF_00543 1.25e-82 - - - - - - - -
MDIBLFOF_00544 1.51e-219 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MDIBLFOF_00545 5.51e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDIBLFOF_00546 2.46e-307 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
MDIBLFOF_00547 4.29e-203 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
MDIBLFOF_00548 7.36e-281 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
MDIBLFOF_00549 1.38e-103 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDIBLFOF_00550 1.27e-182 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
MDIBLFOF_00551 4.66e-61 - - - - - - - -
MDIBLFOF_00552 8.09e-31 - - - - - - - -
MDIBLFOF_00554 7.14e-316 - - - NU - - - Tfp pilus assembly protein FimV
MDIBLFOF_00555 2.16e-282 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MDIBLFOF_00556 4.85e-299 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MDIBLFOF_00557 0.0 - - - I - - - acetylesterase activity
MDIBLFOF_00558 3.96e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MDIBLFOF_00559 1.03e-197 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDIBLFOF_00560 3.9e-244 - - - S - - - Domain of unknown function (DUF1963)
MDIBLFOF_00561 1.2e-19 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MDIBLFOF_00562 4.54e-53 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MDIBLFOF_00563 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
MDIBLFOF_00564 1.07e-163 - - - S - - - zinc-ribbon domain
MDIBLFOF_00565 1.9e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
MDIBLFOF_00566 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
MDIBLFOF_00567 0.000194 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDIBLFOF_00569 4.31e-259 - - - K - - - WYL domain
MDIBLFOF_00570 5.5e-199 - - - S - - - Aldo/keto reductase family
MDIBLFOF_00571 8.97e-223 dkgV - - C - - - Aldo/keto reductase family
MDIBLFOF_00572 1.5e-100 - - - S - - - Domain of unknown function (DUF4186)
MDIBLFOF_00575 2.68e-232 - - - S - - - Protein conserved in bacteria
MDIBLFOF_00576 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MDIBLFOF_00577 8.79e-284 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MDIBLFOF_00578 1.08e-145 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
MDIBLFOF_00579 1.84e-151 - - - - - - - -
MDIBLFOF_00580 3.31e-157 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MDIBLFOF_00581 1.38e-166 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
MDIBLFOF_00582 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
MDIBLFOF_00583 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MDIBLFOF_00584 0.0 - - - S - - - Domain of unknown function (DUF5067)
MDIBLFOF_00585 2e-75 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator Superfamily
MDIBLFOF_00586 1.03e-242 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MDIBLFOF_00587 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
MDIBLFOF_00588 5.07e-157 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
MDIBLFOF_00589 4.62e-224 - - - - - - - -
MDIBLFOF_00590 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDIBLFOF_00591 1.96e-226 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MDIBLFOF_00592 3.88e-213 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDIBLFOF_00593 3.03e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDIBLFOF_00594 1.1e-60 - - - M - - - Lysin motif
MDIBLFOF_00595 2.55e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDIBLFOF_00596 3.23e-290 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MDIBLFOF_00597 0.0 - - - L - - - DNA helicase
MDIBLFOF_00598 8.85e-118 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MDIBLFOF_00599 3.42e-259 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDIBLFOF_00600 2.29e-96 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MDIBLFOF_00601 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
MDIBLFOF_00602 2.48e-231 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDIBLFOF_00603 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDIBLFOF_00604 8.76e-261 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDIBLFOF_00605 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDIBLFOF_00606 4.49e-297 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
MDIBLFOF_00607 6.35e-276 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDIBLFOF_00608 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MDIBLFOF_00609 2.14e-234 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
MDIBLFOF_00612 2.9e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDIBLFOF_00613 6.45e-302 - - - G - - - Major Facilitator Superfamily
MDIBLFOF_00614 2.87e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MDIBLFOF_00615 5.33e-286 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MDIBLFOF_00616 5.59e-168 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MDIBLFOF_00617 8.32e-276 - - - GK - - - ROK family
MDIBLFOF_00618 5.93e-196 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDIBLFOF_00619 4.41e-309 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
MDIBLFOF_00620 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MDIBLFOF_00621 5.3e-243 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_00622 2.16e-248 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_00623 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDIBLFOF_00624 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
MDIBLFOF_00625 3.73e-126 - - - F - - - NUDIX domain
MDIBLFOF_00627 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
MDIBLFOF_00628 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MDIBLFOF_00629 1.46e-165 - 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MDIBLFOF_00630 3.61e-309 - 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp
MDIBLFOF_00631 3.24e-291 - 2.6.1.33 - M ko:K20429 - ko00000,ko01000 DegT/DnrJ/EryC1/StrS aminotransferase family
MDIBLFOF_00632 1.26e-244 - - - V - - - Acetyltransferase (GNAT) domain
MDIBLFOF_00633 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDIBLFOF_00634 9.94e-149 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDIBLFOF_00635 3.35e-84 - - - - - - - -
MDIBLFOF_00636 6.49e-249 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MDIBLFOF_00637 1.13e-231 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MDIBLFOF_00639 6.06e-119 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDIBLFOF_00640 3.39e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDIBLFOF_00641 4.14e-173 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
MDIBLFOF_00642 7.2e-12 - - - S - - - Spermine/spermidine synthase domain
MDIBLFOF_00643 3.07e-137 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDIBLFOF_00644 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
MDIBLFOF_00645 5.46e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDIBLFOF_00646 2.91e-229 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MDIBLFOF_00647 1.86e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MDIBLFOF_00648 8.34e-194 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDIBLFOF_00649 3.52e-144 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDIBLFOF_00650 5.17e-192 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
MDIBLFOF_00651 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MDIBLFOF_00652 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MDIBLFOF_00653 4.74e-211 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
MDIBLFOF_00654 5.66e-295 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
MDIBLFOF_00655 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
MDIBLFOF_00656 4.02e-113 - - - - - - - -
MDIBLFOF_00657 2.04e-253 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MDIBLFOF_00658 2.1e-245 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
MDIBLFOF_00659 2.67e-56 - - - - - - - -
MDIBLFOF_00660 4.74e-236 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MDIBLFOF_00661 4.8e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_00662 3.06e-211 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
MDIBLFOF_00663 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDIBLFOF_00664 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MDIBLFOF_00665 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MDIBLFOF_00666 2.46e-216 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
MDIBLFOF_00667 5.76e-191 - - - S - - - Protein of unknown function (DUF3710)
MDIBLFOF_00668 1.87e-172 - - - S - - - Protein of unknown function (DUF3159)
MDIBLFOF_00669 8.8e-312 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDIBLFOF_00670 1.64e-142 - - - - - - - -
MDIBLFOF_00674 2.69e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDIBLFOF_00675 1.53e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDIBLFOF_00676 2.04e-149 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDIBLFOF_00677 1.46e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
MDIBLFOF_00678 1.51e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MDIBLFOF_00679 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDIBLFOF_00680 4.79e-129 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDIBLFOF_00681 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDIBLFOF_00682 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MDIBLFOF_00683 6.96e-83 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDIBLFOF_00684 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDIBLFOF_00685 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDIBLFOF_00686 3.77e-95 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MDIBLFOF_00687 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
MDIBLFOF_00688 4.08e-221 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDIBLFOF_00689 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
MDIBLFOF_00690 5.51e-199 - - - E - - - Transglutaminase/protease-like homologues
MDIBLFOF_00692 2.09e-45 - - - - - - - -
MDIBLFOF_00693 4.19e-20 tnp3503b - - L - - - Transposase and inactivated derivatives
MDIBLFOF_00694 8.95e-225 - - - - - - - -
MDIBLFOF_00695 1.92e-240 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MDIBLFOF_00696 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDIBLFOF_00697 8.76e-124 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDIBLFOF_00698 9.94e-303 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDIBLFOF_00699 1.78e-304 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
MDIBLFOF_00700 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDIBLFOF_00701 6.9e-142 - - - - - - - -
MDIBLFOF_00702 5.18e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
MDIBLFOF_00703 1.28e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDIBLFOF_00704 4.34e-261 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDIBLFOF_00705 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
MDIBLFOF_00706 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MDIBLFOF_00707 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MDIBLFOF_00709 2.65e-53 - - - M - - - Spy0128-like isopeptide containing domain
MDIBLFOF_00710 4.73e-05 - - - O ko:K18546 - ko00000,ko01000,ko01002 Peptidase s1 and s6 chymotrypsin hap
MDIBLFOF_00711 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
MDIBLFOF_00712 3.56e-198 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MDIBLFOF_00713 1.12e-270 - - - I - - - Diacylglycerol kinase catalytic domain
MDIBLFOF_00714 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
MDIBLFOF_00715 2.32e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDIBLFOF_00717 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
MDIBLFOF_00719 1.06e-121 - - - - - - - -
MDIBLFOF_00720 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDIBLFOF_00721 7.54e-240 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
MDIBLFOF_00722 1.43e-181 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MDIBLFOF_00723 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDIBLFOF_00724 1.18e-162 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
MDIBLFOF_00725 0.0 tcsS3 - - KT - - - PspC domain
MDIBLFOF_00726 0.0 pspC - - KT - - - PspC domain
MDIBLFOF_00727 8.22e-199 - - - - - - - -
MDIBLFOF_00728 9.55e-146 - - - S - - - Protein of unknown function (DUF4125)
MDIBLFOF_00729 0.0 - - - S - - - Domain of unknown function (DUF4037)
MDIBLFOF_00730 4.31e-277 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
MDIBLFOF_00732 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MDIBLFOF_00733 2.89e-224 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MDIBLFOF_00734 3.69e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDIBLFOF_00736 9.33e-153 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MDIBLFOF_00737 3.23e-288 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MDIBLFOF_00738 4.6e-53 - - - - - - - -
MDIBLFOF_00739 1.05e-274 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MDIBLFOF_00740 2.89e-229 - - - S - - - CHAP domain
MDIBLFOF_00741 1.38e-152 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MDIBLFOF_00742 1.31e-244 - - - T - - - Universal stress protein family
MDIBLFOF_00743 4.35e-94 - - - O - - - OsmC-like protein
MDIBLFOF_00744 4.99e-223 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDIBLFOF_00745 5.46e-165 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
MDIBLFOF_00746 2.34e-124 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
MDIBLFOF_00747 2.56e-249 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MDIBLFOF_00748 1.86e-31 - - - E - - - Branched-chain amino acid transport protein (AzlD)
MDIBLFOF_00749 5.06e-145 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_00750 1.94e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
MDIBLFOF_00751 4.37e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MDIBLFOF_00752 2e-09 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
MDIBLFOF_00753 1.38e-235 - - - - - - - -
MDIBLFOF_00754 6.72e-140 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MDIBLFOF_00755 1.66e-229 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
MDIBLFOF_00756 1.64e-138 - - - - - - - -
MDIBLFOF_00757 5.05e-153 - - - K - - - Transcriptional regulatory protein, C terminal
MDIBLFOF_00758 1.71e-302 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MDIBLFOF_00759 1.91e-235 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MDIBLFOF_00760 1.53e-113 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
MDIBLFOF_00761 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MDIBLFOF_00762 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
MDIBLFOF_00763 2.71e-23 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
MDIBLFOF_00765 4.73e-196 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDIBLFOF_00766 5.63e-255 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MDIBLFOF_00767 5.79e-110 - - - S - - - Domain of unknown function (DUF4190)
MDIBLFOF_00770 7.05e-270 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
MDIBLFOF_00771 5.42e-227 - - - M - - - Glycosyltransferase like family 2
MDIBLFOF_00772 0.0 - - - S - - - AI-2E family transporter
MDIBLFOF_00773 3.97e-295 - - - M - - - Glycosyl transferase family 21
MDIBLFOF_00774 4.56e-215 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_00775 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MDIBLFOF_00776 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
MDIBLFOF_00777 3.48e-269 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDIBLFOF_00778 2.65e-127 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MDIBLFOF_00779 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDIBLFOF_00780 2.05e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MDIBLFOF_00781 3.21e-210 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MDIBLFOF_00782 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MDIBLFOF_00783 2.35e-107 - - - S - - - Protein of unknown function (DUF3180)
MDIBLFOF_00784 1.88e-219 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
MDIBLFOF_00785 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
MDIBLFOF_00786 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
MDIBLFOF_00787 8.64e-24 - - - M - - - domain, Protein
MDIBLFOF_00788 1.9e-73 - - - M - - - domain, Protein
MDIBLFOF_00789 1.76e-161 - - - - - - - -
MDIBLFOF_00790 1.06e-148 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDIBLFOF_00791 1.27e-22 - - - S - - - Protein of unknown function (DUF979)
MDIBLFOF_00792 3.61e-65 - - - S - - - DUF218 domain
MDIBLFOF_00794 1.64e-148 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
MDIBLFOF_00795 5.09e-202 - - - I - - - alpha/beta hydrolase fold
MDIBLFOF_00796 6.7e-74 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
MDIBLFOF_00797 0.0 - - - S - - - ATPases associated with a variety of cellular activities
MDIBLFOF_00798 3.68e-229 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MDIBLFOF_00799 8.66e-16 - - - EGP - - - Major facilitator superfamily
MDIBLFOF_00800 1.74e-66 - - - EGP - - - Major facilitator superfamily
MDIBLFOF_00801 6.76e-49 - - - C - - - Aldo/keto reductase family
MDIBLFOF_00802 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
MDIBLFOF_00803 1.27e-271 - - - S - - - Psort location Cytoplasmic, score 8.87
MDIBLFOF_00804 3.31e-39 - - - L - - - Transposase
MDIBLFOF_00806 2.03e-191 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
MDIBLFOF_00807 1.87e-182 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MDIBLFOF_00808 2.85e-05 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_00809 1.23e-210 - - - EG - - - EamA-like transporter family
MDIBLFOF_00810 0.0 - - - JKL - - - helicase superfamily c-terminal domain
MDIBLFOF_00811 7.95e-189 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MDIBLFOF_00812 1.6e-218 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
MDIBLFOF_00813 1.52e-145 - - - - - - - -
MDIBLFOF_00814 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
MDIBLFOF_00816 2.74e-209 - - - G ko:K05340 - ko00000,ko02000 Sugar transport protein
MDIBLFOF_00817 3.38e-252 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
MDIBLFOF_00819 1.85e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MDIBLFOF_00820 1.17e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDIBLFOF_00821 9.44e-234 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDIBLFOF_00822 1.11e-79 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
MDIBLFOF_00823 7.44e-151 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
MDIBLFOF_00824 1.06e-260 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
MDIBLFOF_00825 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MDIBLFOF_00826 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
MDIBLFOF_00827 2.81e-164 - - - KT ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
MDIBLFOF_00828 1.91e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MDIBLFOF_00829 1.71e-206 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDIBLFOF_00830 0.0 - - - L - - - PIF1-like helicase
MDIBLFOF_00832 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDIBLFOF_00834 6.9e-157 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
MDIBLFOF_00835 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
MDIBLFOF_00836 1.47e-191 - - - S - - - Short repeat of unknown function (DUF308)
MDIBLFOF_00837 6.17e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MDIBLFOF_00838 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
MDIBLFOF_00839 2.92e-131 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
MDIBLFOF_00840 1.04e-249 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
MDIBLFOF_00841 2.16e-103 - - - EGP - - - Major Facilitator Superfamily
MDIBLFOF_00842 1.74e-118 - - - K - - - acetyltransferase
MDIBLFOF_00843 0.0 - - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MDIBLFOF_00844 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_00845 5.53e-285 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MDIBLFOF_00846 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
MDIBLFOF_00847 4.84e-297 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MDIBLFOF_00848 1.49e-309 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
MDIBLFOF_00849 1.45e-177 hflK - - O - - - prohibitin homologues
MDIBLFOF_00850 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
MDIBLFOF_00851 4.8e-73 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MDIBLFOF_00852 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDIBLFOF_00853 0.0 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MDIBLFOF_00854 4.49e-306 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
MDIBLFOF_00855 8.59e-23 - - - K - - - Helix-turn-helix domain
MDIBLFOF_00856 7.33e-12 - - - S - - - Protein of unknown function (DUF2442)
MDIBLFOF_00857 5.41e-30 - - - L - - - Helix-turn-helix domain
MDIBLFOF_00858 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
MDIBLFOF_00859 2.47e-26 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MDIBLFOF_00860 2.17e-243 - - - K - - - Periplasmic binding protein domain
MDIBLFOF_00861 3.55e-134 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
MDIBLFOF_00862 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MDIBLFOF_00863 1.3e-89 - - - G ko:K02027 - ko00000,ko00002,ko02000 carbohydrate transport
MDIBLFOF_00864 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDIBLFOF_00865 2.65e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MDIBLFOF_00866 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
MDIBLFOF_00867 1.41e-217 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_00868 5.04e-207 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_00869 1.38e-183 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
MDIBLFOF_00870 2.91e-195 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_00871 2.08e-239 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDIBLFOF_00872 3.01e-117 - - - K - - - Putative zinc ribbon domain
MDIBLFOF_00873 7.23e-161 - - - S - - - GyrI-like small molecule binding domain
MDIBLFOF_00874 3.04e-124 - - - L - - - DNA integration
MDIBLFOF_00876 8.13e-82 - - - - - - - -
MDIBLFOF_00877 5.64e-153 merR2 - - K - - - helix_turn_helix, mercury resistance
MDIBLFOF_00878 2.88e-96 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
MDIBLFOF_00879 3.22e-181 - - - S - - - Bacterial protein of unknown function (DUF881)
MDIBLFOF_00880 2.78e-57 sbp - - S - - - Protein of unknown function (DUF1290)
MDIBLFOF_00881 1.13e-222 - - - S - - - Bacterial protein of unknown function (DUF881)
MDIBLFOF_00882 1.57e-151 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDIBLFOF_00883 1.07e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
MDIBLFOF_00884 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
MDIBLFOF_00885 8.92e-144 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
MDIBLFOF_00886 1.12e-246 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDIBLFOF_00887 2.26e-210 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MDIBLFOF_00888 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MDIBLFOF_00889 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MDIBLFOF_00890 9.44e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MDIBLFOF_00891 9.88e-167 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MDIBLFOF_00892 5.17e-56 - - - - - - - -
MDIBLFOF_00893 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MDIBLFOF_00894 2.72e-314 - - - - - - - -
MDIBLFOF_00895 4.72e-212 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MDIBLFOF_00896 6.71e-284 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MDIBLFOF_00897 3.9e-131 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDIBLFOF_00898 3.73e-72 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
MDIBLFOF_00899 6.91e-259 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDIBLFOF_00900 1.83e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDIBLFOF_00901 2.64e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MDIBLFOF_00902 2.79e-176 yebC - - K - - - transcriptional regulatory protein
MDIBLFOF_00903 0.0 - 3.2.1.52 GH20 M ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MDIBLFOF_00904 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDIBLFOF_00905 0.0 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDIBLFOF_00909 3.27e-274 - - - - - - - -
MDIBLFOF_00913 2.89e-199 - - - S - - - PAC2 family
MDIBLFOF_00914 4.73e-215 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MDIBLFOF_00915 8.17e-204 - - - G - - - Fructosamine kinase
MDIBLFOF_00916 6.31e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDIBLFOF_00917 7.15e-277 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDIBLFOF_00918 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
MDIBLFOF_00919 4.49e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MDIBLFOF_00920 3.12e-182 - - - S - - - Protein of unknown function (DUF1275)
MDIBLFOF_00921 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MDIBLFOF_00923 8.61e-308 - - - V - - - MatE
MDIBLFOF_00924 2.44e-208 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDIBLFOF_00925 1.23e-227 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MDIBLFOF_00926 1.2e-45 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
MDIBLFOF_00927 3.84e-189 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDIBLFOF_00928 6.71e-284 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
MDIBLFOF_00929 1.08e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MDIBLFOF_00930 3.02e-227 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MDIBLFOF_00931 2.13e-230 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
MDIBLFOF_00932 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDIBLFOF_00933 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDIBLFOF_00934 9.44e-94 - - - - - - - -
MDIBLFOF_00935 3.65e-08 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MDIBLFOF_00936 8.67e-151 - - - K - - - Transcriptional regulatory protein, C terminal
MDIBLFOF_00937 0.0 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MDIBLFOF_00938 1.31e-178 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MDIBLFOF_00939 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
MDIBLFOF_00940 4.81e-253 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MDIBLFOF_00941 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MDIBLFOF_00942 1.41e-263 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
MDIBLFOF_00943 1.28e-277 - - - GK - - - ROK family
MDIBLFOF_00944 4.48e-228 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MDIBLFOF_00945 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
MDIBLFOF_00946 1.93e-215 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
MDIBLFOF_00947 3.93e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_00948 7.64e-316 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDIBLFOF_00949 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDIBLFOF_00950 2.68e-96 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MDIBLFOF_00951 1.82e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MDIBLFOF_00952 2.19e-291 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MDIBLFOF_00953 1.27e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
MDIBLFOF_00954 7.62e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDIBLFOF_00955 6.31e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MDIBLFOF_00956 2.6e-163 - - - S - - - alpha beta
MDIBLFOF_00957 4.78e-188 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDIBLFOF_00958 3.07e-188 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MDIBLFOF_00959 4.26e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDIBLFOF_00960 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
MDIBLFOF_00961 5.1e-118 - - - - - - - -
MDIBLFOF_00962 1.59e-255 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
MDIBLFOF_00963 1.35e-306 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
MDIBLFOF_00964 0.0 - - - G - - - ABC transporter substrate-binding protein
MDIBLFOF_00965 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
MDIBLFOF_00966 1.34e-167 - - - M - - - Peptidase family M23
MDIBLFOF_00968 1.13e-250 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDIBLFOF_00969 9.98e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
MDIBLFOF_00970 1.71e-204 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
MDIBLFOF_00971 7.36e-152 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
MDIBLFOF_00972 1.05e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MDIBLFOF_00973 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
MDIBLFOF_00974 1.23e-164 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
MDIBLFOF_00975 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MDIBLFOF_00976 6.48e-215 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MDIBLFOF_00977 2.45e-218 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MDIBLFOF_00978 4.05e-207 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
MDIBLFOF_00979 0.0 - - - E - - - Serine carboxypeptidase
MDIBLFOF_00980 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
MDIBLFOF_00981 4.7e-182 - - - S - - - Domain of unknown function (DUF4194)
MDIBLFOF_00982 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
MDIBLFOF_00983 8.85e-209 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MDIBLFOF_00984 8.22e-85 - - - K - - - Protein of unknown function, DUF488
MDIBLFOF_00985 1.25e-150 - - - J - - - Acetyltransferase (GNAT) domain
MDIBLFOF_00986 7.66e-117 - - - K - - - FR47-like protein
MDIBLFOF_00987 1.26e-65 - - - K - - - Transcriptional regulator
MDIBLFOF_00988 5.16e-59 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
MDIBLFOF_00989 4.46e-46 - - - S - - - Carbon-nitrogen hydrolase
MDIBLFOF_00991 4.18e-237 - - - S - - - Acetyltransferase (GNAT) domain
MDIBLFOF_00992 8.42e-172 - - - S - - - SOS response associated peptidase (SRAP)
MDIBLFOF_00993 1.9e-164 - - - - - - - -
MDIBLFOF_00994 1.31e-103 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDIBLFOF_00995 6.84e-227 - - - M - - - heme binding
MDIBLFOF_00996 7.42e-102 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MDIBLFOF_00998 4.28e-198 - - - - - - - -
MDIBLFOF_00999 1.1e-13 - - - CE ko:K03294 - ko00000 Amino acid permease
MDIBLFOF_01000 3.31e-143 - - - S - - - Putative ABC-transporter type IV
MDIBLFOF_01001 5.99e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MDIBLFOF_01002 7.92e-247 - - - V - - - VanZ like family
MDIBLFOF_01003 3.27e-190 - - - KT - - - RESPONSE REGULATOR receiver
MDIBLFOF_01004 4.75e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
MDIBLFOF_01005 1.2e-188 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
MDIBLFOF_01006 6.92e-171 - - - C - - - Putative TM nitroreductase
MDIBLFOF_01007 2.07e-161 - - - - - - - -
MDIBLFOF_01009 0.0 treS_1 - - G - - - Alpha amylase, catalytic domain
MDIBLFOF_01010 1.26e-100 - - - S - - - Bacterial PH domain
MDIBLFOF_01011 1.65e-177 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
MDIBLFOF_01012 6.1e-89 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDIBLFOF_01013 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDIBLFOF_01015 6.24e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDIBLFOF_01016 5.93e-187 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDIBLFOF_01017 4.42e-121 - - - - - - - -
MDIBLFOF_01018 5.92e-299 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDIBLFOF_01019 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
MDIBLFOF_01020 2.18e-156 - - - S - - - ABC-2 family transporter protein
MDIBLFOF_01021 6.5e-163 - - - S - - - ABC-2 family transporter protein
MDIBLFOF_01022 1.05e-225 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_01023 6.98e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MDIBLFOF_01024 1.24e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
MDIBLFOF_01025 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MDIBLFOF_01026 3.15e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDIBLFOF_01027 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
MDIBLFOF_01028 5.24e-150 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
MDIBLFOF_01029 4.57e-143 - - - - - - - -
MDIBLFOF_01030 3.26e-175 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MDIBLFOF_01032 6.48e-244 - - - G - - - Haloacid dehalogenase-like hydrolase
MDIBLFOF_01033 2.73e-230 - - - L - - - Tetratricopeptide repeat
MDIBLFOF_01035 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDIBLFOF_01036 2.91e-184 - - - S - - - Putative ABC-transporter type IV
MDIBLFOF_01037 9.62e-142 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MDIBLFOF_01038 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MDIBLFOF_01039 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MDIBLFOF_01040 0.0 - - - K - - - Putative DNA-binding domain
MDIBLFOF_01041 1.03e-152 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MDIBLFOF_01042 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
MDIBLFOF_01043 2.59e-198 - - - S - - - Domain of unknown function (DUF4357)
MDIBLFOF_01044 2e-41 - - - - - - - -
MDIBLFOF_01045 4.14e-92 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
MDIBLFOF_01046 8.68e-229 - - - L - - - Phage integrase family
MDIBLFOF_01047 5.96e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDIBLFOF_01048 1.29e-112 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MDIBLFOF_01049 2.51e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDIBLFOF_01050 4.83e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
MDIBLFOF_01051 4.12e-227 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MDIBLFOF_01052 1.82e-275 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MDIBLFOF_01053 5.5e-262 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MDIBLFOF_01054 1.5e-134 - - - - - - - -
MDIBLFOF_01055 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
MDIBLFOF_01056 1.51e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDIBLFOF_01057 4.53e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDIBLFOF_01058 4.11e-174 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_01059 2.65e-175 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MDIBLFOF_01060 1.12e-54 - - - IQ - - - oxidoreductase activity
MDIBLFOF_01062 7.68e-129 - - - K - - - AraC-like ligand binding domain
MDIBLFOF_01063 1.12e-303 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
MDIBLFOF_01064 6.99e-204 - - - G - - - Phosphoglycerate mutase family
MDIBLFOF_01065 1.59e-79 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
MDIBLFOF_01066 6.42e-240 - - - S - - - Conserved hypothetical protein 698
MDIBLFOF_01067 4.28e-185 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MDIBLFOF_01068 3.18e-153 - - - E - - - haloacid dehalogenase-like hydrolase
MDIBLFOF_01069 0.0 - - - M - - - Glycosyltransferase like family 2
MDIBLFOF_01071 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
MDIBLFOF_01072 2.6e-161 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
MDIBLFOF_01073 1.5e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDIBLFOF_01074 6.57e-66 - - - - - - - -
MDIBLFOF_01075 1.66e-46 - - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MDIBLFOF_01076 7.03e-86 - - - S - - - Zincin-like metallopeptidase
MDIBLFOF_01077 4.48e-112 - - - S - - - Helix-turn-helix
MDIBLFOF_01078 1.46e-268 - - - S - - - Short C-terminal domain
MDIBLFOF_01079 1.1e-30 - - - - - - - -
MDIBLFOF_01082 3.33e-82 - - - - - - - -
MDIBLFOF_01083 0.0 - - - S - - - Prophage endopeptidase tail
MDIBLFOF_01084 2.61e-189 - - - S - - - phage tail
MDIBLFOF_01085 0.0 - - - S - - - Phage-related minor tail protein
MDIBLFOF_01086 1.77e-70 - - - - - - - -
MDIBLFOF_01087 4.54e-108 - - - - - - - -
MDIBLFOF_01088 1.01e-122 - - - - - - - -
MDIBLFOF_01089 1.65e-93 - - - - - - - -
MDIBLFOF_01090 6.59e-96 - - - - - - - -
MDIBLFOF_01091 3.65e-103 - - - - - - - -
MDIBLFOF_01092 2.99e-119 - - - - - - - -
MDIBLFOF_01093 3.74e-85 - - - - - - - -
MDIBLFOF_01094 7.08e-225 - - - S - - - Phage capsid family
MDIBLFOF_01095 2.47e-125 - - - - - - - -
MDIBLFOF_01096 2.73e-58 - - - - - - - -
MDIBLFOF_01097 3.05e-302 - - - - - - - -
MDIBLFOF_01098 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
MDIBLFOF_01099 0.0 - - - S - - - Terminase
MDIBLFOF_01100 1.89e-91 - - - - - - - -
MDIBLFOF_01101 1.32e-148 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
MDIBLFOF_01102 1.14e-86 - - - - ko:K07451 - ko00000,ko01000,ko02048 -
MDIBLFOF_01105 5.69e-44 - - - K - - - Transcriptional regulator
MDIBLFOF_01107 4.2e-96 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
MDIBLFOF_01108 1.27e-46 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
MDIBLFOF_01109 7.48e-184 - - - - - - - -
MDIBLFOF_01111 2.92e-66 - - - - - - - -
MDIBLFOF_01113 5.6e-142 - - - A ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MDIBLFOF_01114 5.31e-107 - - - V - - - HNH endonuclease
MDIBLFOF_01115 1.58e-37 - - - - - - - -
MDIBLFOF_01116 1.12e-213 - - - K - - - Transcriptional regulator
MDIBLFOF_01117 0.0 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
MDIBLFOF_01118 1.39e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
MDIBLFOF_01120 1.66e-48 - - - - - - - -
MDIBLFOF_01122 6.36e-50 - - - - - - - -
MDIBLFOF_01127 5.4e-149 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
MDIBLFOF_01128 4.91e-104 - - - - - - - -
MDIBLFOF_01130 2.84e-48 - - - - - - - -
MDIBLFOF_01131 7.23e-73 - - - - - - - -
MDIBLFOF_01132 7.91e-132 - - - S - - - Virulence protein RhuM family
MDIBLFOF_01133 7.34e-64 - - - - - - - -
MDIBLFOF_01134 2.59e-21 - - - - - - - -
MDIBLFOF_01135 1.31e-58 - - - E - - - IrrE N-terminal-like domain
MDIBLFOF_01136 4.22e-310 - - - L - - - Phage integrase, N-terminal SAM-like domain
MDIBLFOF_01137 1.43e-129 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
MDIBLFOF_01138 4.92e-266 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MDIBLFOF_01139 1.69e-229 - - - I - - - alpha/beta hydrolase fold
MDIBLFOF_01140 1.74e-32 - - - S - - - Rard protein
MDIBLFOF_01141 1.34e-119 - - - E - - - Rard protein
MDIBLFOF_01142 9.65e-42 - - - - - - - -
MDIBLFOF_01143 0.0 - - - S - - - Protein of unknown function DUF262
MDIBLFOF_01144 1.8e-136 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
MDIBLFOF_01145 2.3e-115 - 2.1.1.72 - V ko:K00571 - ko00000,ko01000,ko02048 Eco57I restriction-modification methylase
MDIBLFOF_01146 1.36e-245 - 2.1.1.72 - V ko:K00571 - ko00000,ko01000,ko02048 Eco57I restriction-modification methylase
MDIBLFOF_01147 0.0 - - - L - - - T5orf172
MDIBLFOF_01148 4.98e-17 - - - S - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
MDIBLFOF_01149 6.41e-196 - - - F - - - nucleoside 2-deoxyribosyltransferase
MDIBLFOF_01151 9.08e-286 - - - K - - - Helix-turn-helix domain protein
MDIBLFOF_01153 1.1e-167 - - - - - - - -
MDIBLFOF_01154 1.35e-38 - - - - ko:K07485 - ko00000 -
MDIBLFOF_01155 8.7e-266 - - - L ko:K07485 - ko00000 Transposase
MDIBLFOF_01156 5.95e-139 - - - S - - - Short C-terminal domain
MDIBLFOF_01157 1.07e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDIBLFOF_01158 6.79e-143 - - - S ko:K07126 - ko00000 Sel1-like repeats.
MDIBLFOF_01159 6.98e-197 - - - S ko:K11206 - ko00000,ko01000 Carbon-nitrogen hydrolase
MDIBLFOF_01160 4.56e-209 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_01161 3.37e-312 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
MDIBLFOF_01162 5.23e-107 - - - - - - - -
MDIBLFOF_01163 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MDIBLFOF_01164 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
MDIBLFOF_01165 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
MDIBLFOF_01166 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
MDIBLFOF_01167 4.95e-18 - - - S ko:K07149 - ko00000 Membrane
MDIBLFOF_01168 2.71e-311 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MDIBLFOF_01169 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDIBLFOF_01170 3.91e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MDIBLFOF_01171 4.63e-175 - - - S - - - UPF0126 domain
MDIBLFOF_01172 4.11e-181 - - - T - - - RNA ligase
MDIBLFOF_01173 1.65e-61 - - - S - - - phosphoesterase or phosphohydrolase
MDIBLFOF_01174 1.11e-287 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
MDIBLFOF_01175 1.66e-128 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MDIBLFOF_01176 5.5e-238 - - - S ko:K06889 - ko00000 alpha beta
MDIBLFOF_01177 1.16e-304 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MDIBLFOF_01178 1.08e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
MDIBLFOF_01179 3.99e-258 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
MDIBLFOF_01180 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
MDIBLFOF_01181 1.96e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDIBLFOF_01182 0.0 corC - - S - - - CBS domain
MDIBLFOF_01183 1.82e-130 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDIBLFOF_01184 1.05e-253 phoH - - T ko:K06217 - ko00000 PhoH-like protein
MDIBLFOF_01185 1.37e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MDIBLFOF_01186 5.98e-173 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDIBLFOF_01188 1.78e-208 spoU2 - - J - - - SpoU rRNA Methylase family
MDIBLFOF_01189 1.42e-308 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MDIBLFOF_01190 7.04e-139 - - - S - - - Iron-sulfur cluster assembly protein
MDIBLFOF_01191 4.14e-132 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MDIBLFOF_01192 1.47e-305 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDIBLFOF_01193 2.13e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MDIBLFOF_01194 3.41e-297 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
MDIBLFOF_01195 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
MDIBLFOF_01196 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDIBLFOF_01197 1.31e-05 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
MDIBLFOF_01198 3.46e-154 - - - K - - - helix_turn_helix, Lux Regulon
MDIBLFOF_01199 4.78e-138 - - - - - - - -
MDIBLFOF_01200 1.6e-103 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
MDIBLFOF_01201 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MDIBLFOF_01202 4.5e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MDIBLFOF_01203 5.3e-69 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
MDIBLFOF_01204 2e-250 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDIBLFOF_01205 6.58e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDIBLFOF_01206 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDIBLFOF_01207 7.33e-50 - - - - - - - -
MDIBLFOF_01208 4.03e-85 - - - S - - - Bacterial protein of unknown function (DUF948)
MDIBLFOF_01209 7.56e-174 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
MDIBLFOF_01210 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
MDIBLFOF_01211 1.83e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDIBLFOF_01212 2.83e-174 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MDIBLFOF_01213 2.18e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MDIBLFOF_01214 2.46e-84 - - - S - - - Domain of unknown function (DUF4418)
MDIBLFOF_01215 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDIBLFOF_01216 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
MDIBLFOF_01217 6.52e-139 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDIBLFOF_01218 7.11e-309 pbuX - - F ko:K03458 - ko00000 Permease family
MDIBLFOF_01220 8.63e-56 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDIBLFOF_01222 1.71e-144 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
MDIBLFOF_01223 9.3e-53 - - - - - - - -
MDIBLFOF_01224 5.58e-33 - - - S - - - Adenine-specific methyltransferase EcoRI
MDIBLFOF_01225 1.97e-230 tnp3521a2 - - L - - - Integrase core domain
MDIBLFOF_01226 9e-64 - - - L ko:K07483 - ko00000 Transposase
MDIBLFOF_01227 7.23e-85 - - - D - - - MobA/MobL family
MDIBLFOF_01228 1.36e-101 - - - - - - - -
MDIBLFOF_01230 4.15e-259 - - - L - - - Transposase and inactivated derivatives IS30 family
MDIBLFOF_01231 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MDIBLFOF_01232 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MDIBLFOF_01233 1.13e-289 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MDIBLFOF_01234 8.42e-236 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_01235 1.83e-58 pacL 3.6.3.8, 3.6.3.9 - P ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 ATPase, P-type transporting, HAD superfamily, subfamily IC
MDIBLFOF_01236 1.45e-298 - - - T - - - Histidine kinase
MDIBLFOF_01237 1.54e-153 - - - K - - - helix_turn_helix, Lux Regulon
MDIBLFOF_01238 4.91e-150 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
MDIBLFOF_01239 7.55e-243 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
MDIBLFOF_01240 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MDIBLFOF_01241 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MDIBLFOF_01245 1.46e-37 - - - - - - - -
MDIBLFOF_01246 8.37e-145 - - - S - - - Protein of unknown function (DUF1294)
MDIBLFOF_01248 1.62e-157 - - - - - - - -
MDIBLFOF_01249 0.0 - - - S - - - Domain of unknown function (DUF1846)
MDIBLFOF_01250 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
MDIBLFOF_01251 1.39e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDIBLFOF_01252 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MDIBLFOF_01253 4.88e-140 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
MDIBLFOF_01254 6.39e-173 - - - L - - - Phage integrase family
MDIBLFOF_01256 4.18e-279 - - - - - - - -
MDIBLFOF_01257 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
MDIBLFOF_01258 4.67e-157 - - - L - - - NUDIX domain
MDIBLFOF_01259 2.1e-218 - - - L - - - NIF3 (NGG1p interacting factor 3)
MDIBLFOF_01260 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDIBLFOF_01261 5.44e-161 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
MDIBLFOF_01263 8.13e-141 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MDIBLFOF_01264 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
MDIBLFOF_01265 2.29e-227 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
MDIBLFOF_01266 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDIBLFOF_01267 2.24e-139 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDIBLFOF_01268 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MDIBLFOF_01269 1.21e-210 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDIBLFOF_01270 1.97e-230 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
MDIBLFOF_01271 4.7e-209 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_01272 2.15e-177 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
MDIBLFOF_01273 3.64e-108 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MDIBLFOF_01274 1.99e-131 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
MDIBLFOF_01275 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDIBLFOF_01276 5.39e-163 cseB - - T - - - Response regulator receiver domain protein
MDIBLFOF_01277 5.91e-259 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MDIBLFOF_01278 7.56e-92 umuD - - KT ko:K03503 - ko00000,ko01000,ko01002,ko03400 Peptidase S24-like
MDIBLFOF_01279 4.84e-170 pyrE_1 - - S - - - Phosphoribosyl transferase domain
MDIBLFOF_01280 2.33e-200 - - - T - - - Eukaryotic phosphomannomutase
MDIBLFOF_01281 1.05e-85 - - - S - - - Zincin-like metallopeptidase
MDIBLFOF_01282 0.0 - - - - - - - -
MDIBLFOF_01283 6.3e-104 - - - S - - - Glycosyl transferase, family 2
MDIBLFOF_01284 1.03e-141 - - - - - - - -
MDIBLFOF_01285 1.01e-241 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
MDIBLFOF_01286 4.9e-283 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MDIBLFOF_01287 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MDIBLFOF_01288 1.27e-118 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDIBLFOF_01290 2.63e-121 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MDIBLFOF_01291 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
MDIBLFOF_01292 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDIBLFOF_01293 7.71e-314 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
MDIBLFOF_01294 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDIBLFOF_01295 2.73e-206 - - - K - - - Helix-turn-helix domain, rpiR family
MDIBLFOF_01296 1.74e-292 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MDIBLFOF_01297 2.12e-59 - - - S ko:K06990 - ko00000,ko04812 Memo-like protein
MDIBLFOF_01299 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDIBLFOF_01300 5.85e-228 yogA - - C - - - Zinc-binding dehydrogenase
MDIBLFOF_01301 5.14e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDIBLFOF_01302 5.14e-291 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDIBLFOF_01303 1.38e-92 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MDIBLFOF_01304 3.79e-61 - - - - - - - -
MDIBLFOF_01305 2.26e-165 - - - S - - - TIGRFAM TIGR03943 family protein
MDIBLFOF_01306 3.55e-258 - - - S ko:K07089 - ko00000 Predicted permease
MDIBLFOF_01307 1.07e-32 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
MDIBLFOF_01308 3.05e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
MDIBLFOF_01309 4.38e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MDIBLFOF_01310 4.85e-65 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDIBLFOF_01311 3.75e-63 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
MDIBLFOF_01312 3.82e-180 - - - S - - - cobalamin synthesis protein
MDIBLFOF_01313 1.07e-209 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
MDIBLFOF_01314 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
MDIBLFOF_01315 0.0 - - - S - - - Putative esterase
MDIBLFOF_01316 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
MDIBLFOF_01317 2.18e-306 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MDIBLFOF_01318 2.1e-245 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MDIBLFOF_01319 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDIBLFOF_01320 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
MDIBLFOF_01321 4.01e-44 - - - - - - - -
MDIBLFOF_01322 4.02e-91 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDIBLFOF_01323 4.51e-44 - - - K - - - DNA-binding transcription factor activity
MDIBLFOF_01324 2.92e-193 nnrE - - L - - - Uracil DNA glycosylase superfamily
MDIBLFOF_01325 2.2e-140 - - - S - - - Protein of unknown function (DUF4230)
MDIBLFOF_01326 2.23e-140 - - - - - - - -
MDIBLFOF_01327 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
MDIBLFOF_01328 2.05e-177 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MDIBLFOF_01329 2.71e-298 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDIBLFOF_01330 0.0 - - - M - - - Parallel beta-helix repeats
MDIBLFOF_01331 4.23e-289 - - - M - - - Glycosyl transferase 4-like domain
MDIBLFOF_01332 4.64e-256 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
MDIBLFOF_01334 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDIBLFOF_01335 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDIBLFOF_01336 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDIBLFOF_01337 5.83e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDIBLFOF_01338 8.83e-98 - - - I - - - PAP2 superfamily
MDIBLFOF_01339 2.52e-108 - - - S - - - Esterase-like activity of phytase
MDIBLFOF_01340 1.2e-136 - - - S - - - Esterase-like activity of phytase
MDIBLFOF_01341 1.52e-252 - - - EGP - - - Transmembrane secretion effector
MDIBLFOF_01343 3.8e-135 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDIBLFOF_01344 1.01e-150 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDIBLFOF_01345 1.4e-303 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MDIBLFOF_01346 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MDIBLFOF_01347 0.0 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MDIBLFOF_01348 0.0 - - - S - - - Protein of unknown function DUF262
MDIBLFOF_01349 6.09e-152 - - - K - - - helix_turn_helix, Lux Regulon
MDIBLFOF_01350 0.0 - - - T - - - Histidine kinase
MDIBLFOF_01351 2.17e-151 - - - S - - - Domain of unknown function (DUF5067)
MDIBLFOF_01352 8.71e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
MDIBLFOF_01353 1.17e-218 - - - EG - - - EamA-like transporter family
MDIBLFOF_01354 1.42e-156 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
MDIBLFOF_01355 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MDIBLFOF_01356 1.26e-235 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDIBLFOF_01357 4.27e-175 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MDIBLFOF_01358 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
MDIBLFOF_01359 6.37e-160 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDIBLFOF_01360 1.14e-124 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MDIBLFOF_01361 1.03e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
MDIBLFOF_01362 3.38e-54 - - - S - - - Protein of unknown function (DUF3046)
MDIBLFOF_01363 7.71e-276 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDIBLFOF_01364 1.97e-95 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MDIBLFOF_01367 3.68e-152 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDIBLFOF_01368 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDIBLFOF_01369 2.96e-242 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MDIBLFOF_01370 4.56e-142 - - - - - - - -
MDIBLFOF_01371 8.72e-173 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
MDIBLFOF_01372 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
MDIBLFOF_01373 7.75e-258 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MDIBLFOF_01374 3.42e-158 - - - - - - - -
MDIBLFOF_01375 1.27e-258 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDIBLFOF_01376 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
MDIBLFOF_01377 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MDIBLFOF_01378 9.34e-13 - - - G - - - Major Facilitator Superfamily
MDIBLFOF_01379 1.65e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MDIBLFOF_01380 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
MDIBLFOF_01381 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
MDIBLFOF_01382 7.76e-299 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
MDIBLFOF_01383 3.19e-239 - - - S - - - Protein of unknown function (DUF3071)
MDIBLFOF_01384 2.45e-63 - - - S - - - Domain of unknown function (DUF4193)
MDIBLFOF_01385 1.23e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MDIBLFOF_01386 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDIBLFOF_01388 3.6e-266 - - - E - - - Belongs to the peptidase S1B family
MDIBLFOF_01389 1.78e-89 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
MDIBLFOF_01390 1.65e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MDIBLFOF_01391 3.42e-134 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDIBLFOF_01392 1.17e-213 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDIBLFOF_01393 2.71e-114 - - - P - - - ABC-type metal ion transport system permease component
MDIBLFOF_01394 1.2e-286 - - - S - - - Peptidase dimerisation domain
MDIBLFOF_01395 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MDIBLFOF_01396 2.33e-53 - - - - - - - -
MDIBLFOF_01397 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MDIBLFOF_01399 2.63e-09 - - - K - - - sequence-specific DNA binding
MDIBLFOF_01402 1.54e-29 - - - S ko:K09803 - ko00000 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
MDIBLFOF_01403 1.84e-51 - - - - - - - -
MDIBLFOF_01404 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
MDIBLFOF_01405 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MDIBLFOF_01406 1.13e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MDIBLFOF_01408 3.74e-130 mntP - - P - - - Probably functions as a manganese efflux pump
MDIBLFOF_01409 5.6e-170 - - - - - - - -
MDIBLFOF_01410 4.91e-169 glnR - - KT - - - Transcriptional regulatory protein, C terminal
MDIBLFOF_01411 9.54e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDIBLFOF_01412 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MDIBLFOF_01413 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDIBLFOF_01414 0.0 - - - S - - - domain protein
MDIBLFOF_01415 9.37e-96 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
MDIBLFOF_01416 8.96e-117 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
MDIBLFOF_01417 1.18e-296 - 2.6.1.1 - E ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
MDIBLFOF_01418 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MDIBLFOF_01419 0.0 - - - H - - - Flavin containing amine oxidoreductase
MDIBLFOF_01420 6.51e-69 - - - S - - - Protein of unknown function (DUF2469)
MDIBLFOF_01421 1.96e-251 - - - J - - - Acetyltransferase (GNAT) domain
MDIBLFOF_01422 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDIBLFOF_01423 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDIBLFOF_01424 3.33e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDIBLFOF_01425 9.62e-80 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MDIBLFOF_01426 3.77e-81 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MDIBLFOF_01427 1.94e-213 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
MDIBLFOF_01428 2.47e-164 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDIBLFOF_01429 2.93e-297 rmuC - - S ko:K09760 - ko00000 RmuC family
MDIBLFOF_01430 6.68e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
MDIBLFOF_01431 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
MDIBLFOF_01432 0.0 - - - S ko:K03688 - ko00000 ABC1 family
MDIBLFOF_01433 3.15e-44 - - - S - - - granule-associated protein
MDIBLFOF_01434 1.02e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
MDIBLFOF_01435 0.0 murE - - M - - - Domain of unknown function (DUF1727)
MDIBLFOF_01436 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MDIBLFOF_01437 0.0 dinF - - V - - - MatE
MDIBLFOF_01438 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
MDIBLFOF_01439 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
MDIBLFOF_01440 1.48e-305 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
MDIBLFOF_01441 6.66e-281 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDIBLFOF_01443 1.17e-172 icaR - - K - - - Bacterial regulatory proteins, tetR family
MDIBLFOF_01444 6.85e-255 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
MDIBLFOF_01445 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
MDIBLFOF_01446 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
MDIBLFOF_01447 2.36e-14 - - - S ko:K16926 - ko00000,ko00002,ko02000 Hypothetical bacterial integral membrane protein (Trep_Strep)
MDIBLFOF_01448 4.82e-114 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MDIBLFOF_01449 7.12e-109 - - - - - - - -
MDIBLFOF_01450 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
MDIBLFOF_01451 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_01452 2.29e-106 - - - K - - - Winged helix DNA-binding domain
MDIBLFOF_01453 0.0 - - - M - - - LPXTG cell wall anchor motif
MDIBLFOF_01454 8.28e-238 - - - M ko:K20276 ko02024,map02024 ko00000,ko00001 chlorophyll binding
MDIBLFOF_01455 3.06e-271 - - - M ko:K20276 ko02024,map02024 ko00000,ko00001 chlorophyll binding
MDIBLFOF_01456 8.59e-224 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MDIBLFOF_01458 1.72e-209 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDIBLFOF_01459 1.13e-307 - - - S - - - Putative ABC-transporter type IV
MDIBLFOF_01460 7e-104 - - - - - - - -
MDIBLFOF_01461 3.26e-48 - - - Q - - - phosphatase activity
MDIBLFOF_01462 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
MDIBLFOF_01463 1.29e-66 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MDIBLFOF_01464 1.2e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MDIBLFOF_01465 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDIBLFOF_01466 1.13e-86 - - - S - - - haloacid dehalogenase-like hydrolase
MDIBLFOF_01467 1.39e-06 - - - S - - - haloacid dehalogenase-like hydrolase
MDIBLFOF_01468 1.5e-167 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
MDIBLFOF_01469 4.88e-104 - - - S - - - FMN_bind
MDIBLFOF_01470 2.6e-189 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_01471 5.96e-271 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MDIBLFOF_01472 3.23e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MDIBLFOF_01473 3.04e-296 - - - S - - - Predicted membrane protein (DUF2318)
MDIBLFOF_01474 2.38e-150 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
MDIBLFOF_01475 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
MDIBLFOF_01476 3.52e-32 - - - G - - - MFS/sugar transport protein
MDIBLFOF_01477 2.48e-257 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDIBLFOF_01478 1.91e-109 - - - S - - - Fic/DOC family
MDIBLFOF_01480 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDIBLFOF_01481 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
MDIBLFOF_01482 9.38e-256 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDIBLFOF_01483 3.65e-273 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MDIBLFOF_01484 2.08e-158 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDIBLFOF_01485 2.33e-191 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDIBLFOF_01489 8.51e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MDIBLFOF_01490 9.86e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
MDIBLFOF_01491 5.44e-165 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MDIBLFOF_01492 8.66e-310 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MDIBLFOF_01493 6.31e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDIBLFOF_01494 3.6e-305 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MDIBLFOF_01495 2.84e-137 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MDIBLFOF_01496 2.13e-310 - - - EGP - - - Major Facilitator Superfamily
MDIBLFOF_01497 3.26e-276 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MDIBLFOF_01498 7.76e-236 - - - L - - - Excalibur calcium-binding domain
MDIBLFOF_01499 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MDIBLFOF_01500 3.04e-123 - - - D - - - nuclear chromosome segregation
MDIBLFOF_01501 2.23e-164 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDIBLFOF_01502 9.04e-186 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MDIBLFOF_01503 8.18e-243 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
MDIBLFOF_01504 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
MDIBLFOF_01505 1.32e-119 - - - L - - - Transposase and inactivated derivatives IS30 family
MDIBLFOF_01506 6.85e-214 - - - C - - - Oxidoreductase, aldo keto reductase family protein
MDIBLFOF_01507 1.26e-55 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MDIBLFOF_01508 3.47e-128 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MDIBLFOF_01509 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDIBLFOF_01510 1.03e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDIBLFOF_01511 4e-96 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
MDIBLFOF_01512 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MDIBLFOF_01513 1.85e-123 lemA - - S ko:K03744 - ko00000 LemA family
MDIBLFOF_01514 2.46e-147 xylR - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
MDIBLFOF_01515 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MDIBLFOF_01516 8.32e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDIBLFOF_01517 3.14e-155 - - - - - - - -
MDIBLFOF_01518 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
MDIBLFOF_01520 4.39e-209 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
MDIBLFOF_01521 5.82e-130 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDIBLFOF_01522 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
MDIBLFOF_01523 0.0 pccB - - I - - - Carboxyl transferase domain
MDIBLFOF_01524 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MDIBLFOF_01525 2.14e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MDIBLFOF_01526 4.75e-196 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
MDIBLFOF_01527 0.0 - - - - - - - -
MDIBLFOF_01528 8.27e-187 - - - QT - - - PucR C-terminal helix-turn-helix domain
MDIBLFOF_01529 3.84e-169 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MDIBLFOF_01530 1.39e-66 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MDIBLFOF_01531 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDIBLFOF_01532 2.73e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDIBLFOF_01533 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDIBLFOF_01534 5.66e-192 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDIBLFOF_01535 7.5e-98 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDIBLFOF_01536 1.21e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDIBLFOF_01538 3.54e-188 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MDIBLFOF_01539 1.7e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MDIBLFOF_01541 3.88e-128 - - - L - - - Phage integrase family
MDIBLFOF_01543 1.73e-50 - - - - - - - -
MDIBLFOF_01544 5.44e-18 - - - S - - - Putative phage holin Dp-1
MDIBLFOF_01545 1.13e-112 - - - M - - - NLP P60 protein
MDIBLFOF_01546 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDIBLFOF_01547 9.16e-112 - - - K - - - Transcriptional regulator
MDIBLFOF_01549 0.0 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
MDIBLFOF_01550 5.49e-237 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
MDIBLFOF_01551 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MDIBLFOF_01552 3.34e-211 - - - S - - - Glutamine amidotransferase domain
MDIBLFOF_01553 3.28e-176 - - - T ko:K06950 - ko00000 HD domain
MDIBLFOF_01554 2.81e-270 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MDIBLFOF_01555 0.0 - - - V - - - ABC transporter permease
MDIBLFOF_01556 0.0 - - - H - - - Protein of unknown function (DUF4012)
MDIBLFOF_01557 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
MDIBLFOF_01558 1.93e-211 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MDIBLFOF_01559 2.41e-37 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
MDIBLFOF_01560 0.00015 - - - - - - - -
MDIBLFOF_01561 0.0 - - - - - - - -
MDIBLFOF_01562 4.05e-268 - - - S - - - Glycosyltransferase, group 2 family protein
MDIBLFOF_01563 4.68e-77 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MDIBLFOF_01564 5.26e-130 - - - - - - - -
MDIBLFOF_01565 6.66e-256 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
MDIBLFOF_01566 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MDIBLFOF_01567 3.3e-197 - - - D - - - bacterial-type flagellum organization
MDIBLFOF_01568 6.74e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
MDIBLFOF_01569 7.19e-155 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
MDIBLFOF_01570 4.59e-113 - - - NU - - - Type II secretion system (T2SS), protein F
MDIBLFOF_01571 3.96e-55 - - - S - - - Protein of unknown function (DUF4244)
MDIBLFOF_01572 1.28e-73 - - - U - - - TadE-like protein
MDIBLFOF_01573 1.04e-72 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
MDIBLFOF_01574 1.88e-273 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
MDIBLFOF_01575 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
MDIBLFOF_01576 1.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDIBLFOF_01577 2.29e-176 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
MDIBLFOF_01578 1.42e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
MDIBLFOF_01580 7.91e-271 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDIBLFOF_01581 1.77e-148 - - - - - - - -
MDIBLFOF_01582 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
MDIBLFOF_01583 3.11e-19 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
MDIBLFOF_01584 0.0 - - - S - - - Calcineurin-like phosphoesterase
MDIBLFOF_01585 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MDIBLFOF_01586 0.0 pbp5 - - M - - - Transglycosylase
MDIBLFOF_01587 1.16e-271 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MDIBLFOF_01588 1.08e-115 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDIBLFOF_01589 1.26e-145 - - - S - - - Protein of unknown function (DUF3000)
MDIBLFOF_01590 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
MDIBLFOF_01591 9.36e-310 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDIBLFOF_01592 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
MDIBLFOF_01593 4.05e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDIBLFOF_01594 6.56e-164 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDIBLFOF_01595 5.01e-311 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDIBLFOF_01598 7.4e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
MDIBLFOF_01599 8.28e-291 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MDIBLFOF_01600 4.26e-222 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MDIBLFOF_01601 6.09e-152 safC - - S - - - O-methyltransferase
MDIBLFOF_01602 7.2e-235 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
MDIBLFOF_01603 2.23e-93 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
MDIBLFOF_01604 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
MDIBLFOF_01605 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
MDIBLFOF_01606 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
MDIBLFOF_01607 2.09e-211 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MDIBLFOF_01608 5.71e-201 - - - S - - - Putative ABC-transporter type IV
MDIBLFOF_01609 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
MDIBLFOF_01610 1.53e-215 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_01611 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MDIBLFOF_01612 5.21e-288 - - - I - - - PAP2 superfamily
MDIBLFOF_01613 2.92e-171 - - - K - - - helix_turn_helix, Lux Regulon
MDIBLFOF_01614 0.0 - - - T - - - Histidine kinase
MDIBLFOF_01615 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
MDIBLFOF_01616 6.07e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDIBLFOF_01617 1.03e-213 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
MDIBLFOF_01618 1.1e-188 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
MDIBLFOF_01619 7.72e-239 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MDIBLFOF_01620 3.03e-233 acoB 1.2.4.1, 1.2.4.4 - C ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MDIBLFOF_01621 4.7e-262 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDIBLFOF_01622 1.88e-120 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_01623 2.46e-290 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MDIBLFOF_01624 7.17e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDIBLFOF_01625 4.65e-312 - - - K - - - Fic/DOC family
MDIBLFOF_01626 1.58e-161 - - - E - - - Psort location Cytoplasmic, score 8.87
MDIBLFOF_01627 5.59e-78 yccF - - S - - - Inner membrane component domain
MDIBLFOF_01628 6.35e-201 - - - J - - - Methyltransferase domain
MDIBLFOF_01629 4.93e-107 - - - S - - - Cupin 2, conserved barrel domain protein
MDIBLFOF_01630 0.0 - - - KLT - - - Protein tyrosine kinase
MDIBLFOF_01631 1.66e-100 - - - K - - - Psort location Cytoplasmic, score
MDIBLFOF_01633 1.29e-189 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDIBLFOF_01634 3.01e-218 - - - S - - - Protein conserved in bacteria
MDIBLFOF_01636 5.92e-313 - - - S ko:K06901 - ko00000,ko02000 Permease family
MDIBLFOF_01638 0.0 - - - G - - - BNR repeat-like domain
MDIBLFOF_01639 7.43e-233 xynB2 1.1.1.169 - E ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 lipolytic protein G-D-S-L family
MDIBLFOF_01640 5.06e-115 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDIBLFOF_01641 5.13e-61 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDIBLFOF_01643 0.0 - - - T - - - Forkhead associated domain
MDIBLFOF_01644 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
MDIBLFOF_01645 2.87e-56 - - - - - - - -
MDIBLFOF_01646 1.22e-140 - - - NO - - - SAF
MDIBLFOF_01647 1.88e-51 - - - S - - - Putative regulatory protein
MDIBLFOF_01648 5.69e-154 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
MDIBLFOF_01649 1.2e-191 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MDIBLFOF_01650 2.36e-268 - - - - - - - -
MDIBLFOF_01651 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDIBLFOF_01652 3.21e-166 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MDIBLFOF_01653 1.01e-75 - - - KLT - - - Associated with various cellular activities
MDIBLFOF_01657 2.71e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
MDIBLFOF_01658 4.03e-282 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MDIBLFOF_01659 3.55e-81 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
MDIBLFOF_01660 2.34e-284 dapC - - E - - - Aminotransferase class I and II
MDIBLFOF_01661 1.89e-306 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDIBLFOF_01663 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
MDIBLFOF_01664 4e-147 yigZ - - S - - - Uncharacterized protein family UPF0029
MDIBLFOF_01665 4.17e-152 - - - - - - - -
MDIBLFOF_01666 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
MDIBLFOF_01667 2.64e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDIBLFOF_01668 1.71e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MDIBLFOF_01669 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
MDIBLFOF_01670 1.75e-297 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MDIBLFOF_01671 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MDIBLFOF_01672 3.91e-213 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MDIBLFOF_01674 5.52e-123 - - - S - - - YwiC-like protein
MDIBLFOF_01675 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MDIBLFOF_01676 6.65e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDIBLFOF_01677 1.34e-154 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MDIBLFOF_01678 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDIBLFOF_01679 1.15e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDIBLFOF_01680 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDIBLFOF_01681 2.21e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDIBLFOF_01682 2.73e-161 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDIBLFOF_01683 2.71e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDIBLFOF_01684 6.77e-51 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MDIBLFOF_01685 9.4e-57 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDIBLFOF_01686 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDIBLFOF_01687 9.32e-70 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDIBLFOF_01688 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDIBLFOF_01689 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDIBLFOF_01690 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MDIBLFOF_01691 7.92e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
MDIBLFOF_01692 2.65e-139 - - - - - - - -
MDIBLFOF_01694 1.67e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDIBLFOF_01695 2.01e-93 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
MDIBLFOF_01696 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
MDIBLFOF_01697 2.65e-127 - - - - - - - -
MDIBLFOF_01699 5.66e-232 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
MDIBLFOF_01700 6.25e-138 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
MDIBLFOF_01701 1.93e-131 - - - D - - - Septum formation initiator
MDIBLFOF_01702 7.41e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDIBLFOF_01703 1.18e-193 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 - E ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 branched-chain-amino-acid transaminase activity
MDIBLFOF_01704 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000,ko01007 chorismate binding enzyme
MDIBLFOF_01705 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDIBLFOF_01706 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDIBLFOF_01707 9.1e-127 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MDIBLFOF_01708 1.97e-186 rfbB2 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MDIBLFOF_01709 1.7e-194 - - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MDIBLFOF_01710 1.21e-252 - - - GM - - - GDP-mannose 4,6 dehydratase
MDIBLFOF_01711 2.58e-165 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MDIBLFOF_01714 1.18e-274 - - - I ko:K13663 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
MDIBLFOF_01715 0.0 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDIBLFOF_01716 9.65e-272 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDIBLFOF_01717 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
MDIBLFOF_01718 1.7e-298 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
MDIBLFOF_01719 1.88e-251 - - - - - - - -
MDIBLFOF_01720 1.7e-194 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_01721 3.07e-244 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
MDIBLFOF_01722 0.0 argE - - E - - - Peptidase dimerisation domain
MDIBLFOF_01723 2.07e-134 - - - S - - - Protein of unknown function (DUF3043)
MDIBLFOF_01724 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MDIBLFOF_01725 8.63e-182 - - - S - - - Domain of unknown function (DUF4191)
MDIBLFOF_01726 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MDIBLFOF_01729 1.5e-15 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
MDIBLFOF_01733 1.9e-98 - - - S - - - GIY-YIG catalytic domain
MDIBLFOF_01734 2.5e-39 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
MDIBLFOF_01735 3.85e-66 - - - L - - - Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MDIBLFOF_01736 7.24e-106 - - - L - - - Phage integrase, N-terminal SAM-like domain
MDIBLFOF_01737 4.08e-203 - - - S - - - Protein conserved in bacteria
MDIBLFOF_01738 2.36e-269 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MDIBLFOF_01739 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDIBLFOF_01740 0.0 - - - S - - - Tetratricopeptide repeat
MDIBLFOF_01741 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDIBLFOF_01742 1.7e-101 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
MDIBLFOF_01743 7.34e-177 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MDIBLFOF_01744 3.37e-270 - - - E - - - Aminotransferase class I and II
MDIBLFOF_01745 5.64e-179 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MDIBLFOF_01746 3.98e-135 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDIBLFOF_01747 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDIBLFOF_01748 0.0 - - - EGP - - - Major Facilitator Superfamily
MDIBLFOF_01750 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
MDIBLFOF_01751 0.0 - - - L - - - DEAD DEAH box helicase
MDIBLFOF_01752 2.49e-255 - - - S - - - Polyphosphate kinase 2 (PPK2)
MDIBLFOF_01753 3.8e-252 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_01754 2.97e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDIBLFOF_01755 5.91e-196 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MDIBLFOF_01756 2.08e-180 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
MDIBLFOF_01757 5.55e-121 - - - S - - - Aminoacyl-tRNA editing domain
MDIBLFOF_01758 1.4e-110 - - - K - - - helix_turn_helix, Lux Regulon
MDIBLFOF_01759 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MDIBLFOF_01760 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
MDIBLFOF_01761 5.86e-299 - - - S - - - Domain of Unknown Function (DUF349)
MDIBLFOF_01765 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
MDIBLFOF_01766 4.19e-238 uspA - - T - - - Belongs to the universal stress protein A family
MDIBLFOF_01767 6.33e-253 - - - S - - - Protein of unknown function (DUF3027)
MDIBLFOF_01768 1.23e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MDIBLFOF_01769 2.98e-277 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MDIBLFOF_01771 2.42e-182 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
MDIBLFOF_01772 1.11e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MDIBLFOF_01773 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
MDIBLFOF_01774 3.7e-70 - - - - - - - -
MDIBLFOF_01775 0.0 - - - K - - - WYL domain
MDIBLFOF_01776 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MDIBLFOF_01778 1.41e-149 - - - - - - - -
MDIBLFOF_01781 5.93e-191 - - - - - - - -
MDIBLFOF_01782 1.26e-15 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
MDIBLFOF_01784 2.26e-258 - - - M - - - Glycosyl hydrolases family 25
MDIBLFOF_01785 4.73e-31 - - - - - - - -
MDIBLFOF_01787 2.39e-208 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MDIBLFOF_01788 1.09e-233 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MDIBLFOF_01789 0.0 - - - V ko:K07454 - ko00000 regulation of methylation-dependent chromatin silencing
MDIBLFOF_01791 3.6e-287 - - - S - - - Domain of unknown function (DUF4263)
MDIBLFOF_01792 1.65e-116 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
MDIBLFOF_01793 7.48e-186 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MDIBLFOF_01794 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDIBLFOF_01795 6.72e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MDIBLFOF_01796 1.23e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MDIBLFOF_01797 5.57e-120 - - - T - - - Domain of unknown function (DUF4234)
MDIBLFOF_01798 7.9e-130 - - - K - - - Bacterial regulatory proteins, tetR family
MDIBLFOF_01799 3.56e-24 - - - - - - - -
MDIBLFOF_01800 1.02e-64 tam 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
MDIBLFOF_01801 9.61e-54 - - - K - - - Helix-turn-helix
MDIBLFOF_01802 4.89e-285 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
MDIBLFOF_01803 2.47e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
MDIBLFOF_01804 1.32e-225 - - - S ko:K07088 - ko00000 Membrane transport protein
MDIBLFOF_01805 5.07e-120 - - - K - - - Transcriptional regulator PadR-like family
MDIBLFOF_01806 1.02e-171 - - - L ko:K07457 - ko00000 endonuclease III
MDIBLFOF_01807 6.88e-169 - - - S - - - Enoyl-(Acyl carrier protein) reductase
MDIBLFOF_01808 1.97e-311 - - - V - - - MatE
MDIBLFOF_01809 6.61e-231 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MDIBLFOF_01810 1.75e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
MDIBLFOF_01811 4.39e-235 - - - - - - - -
MDIBLFOF_01812 8.25e-53 - - - S - - - Proteins of 100 residues with WXG
MDIBLFOF_01813 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDIBLFOF_01814 1.74e-57 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MDIBLFOF_01815 4.24e-105 - - - S - - - LytR cell envelope-related transcriptional attenuator
MDIBLFOF_01816 7.48e-185 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDIBLFOF_01817 3.5e-251 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
MDIBLFOF_01818 5.18e-228 - - - S - - - Protein of unknown function DUF58
MDIBLFOF_01819 1.78e-121 - - - - - - - -
MDIBLFOF_01820 7.9e-247 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
MDIBLFOF_01821 2.85e-198 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
MDIBLFOF_01822 5.57e-118 - - - - - - - -
MDIBLFOF_01824 0.0 - - - S - - - PGAP1-like protein
MDIBLFOF_01825 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
MDIBLFOF_01826 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
MDIBLFOF_01827 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
MDIBLFOF_01828 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MDIBLFOF_01829 2.03e-26 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MDIBLFOF_01830 3.29e-202 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
MDIBLFOF_01831 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
MDIBLFOF_01832 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
MDIBLFOF_01833 2.25e-178 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
MDIBLFOF_01834 1.29e-233 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDIBLFOF_01835 1.29e-172 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MDIBLFOF_01836 1.9e-52 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDIBLFOF_01839 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MDIBLFOF_01840 1.16e-208 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
MDIBLFOF_01842 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MDIBLFOF_01843 7.76e-234 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MDIBLFOF_01844 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MDIBLFOF_01845 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDIBLFOF_01846 2.31e-230 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
MDIBLFOF_01847 4.88e-198 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MDIBLFOF_01848 7.1e-230 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDIBLFOF_01849 1.75e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDIBLFOF_01850 2.41e-23 - - - K - - - MerR family regulatory protein
MDIBLFOF_01851 1.88e-249 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
MDIBLFOF_01852 3.51e-219 - - - - - - - -
MDIBLFOF_01854 1.76e-19 - - - KLT - - - Protein tyrosine kinase
MDIBLFOF_01856 3.88e-267 - - - S - - - Phage portal protein, SPP1 Gp6-like
MDIBLFOF_01857 6.96e-304 - - - S - - - Terminase
MDIBLFOF_01858 1.33e-12 - - - - - - - -
MDIBLFOF_01859 2.94e-50 - - - L - - - HNH endonuclease
MDIBLFOF_01867 1.41e-60 - - - S - - - Protein of unknwon function (DUF3310)
MDIBLFOF_01868 1.07e-77 - - - A ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MDIBLFOF_01869 2.48e-117 - - - L - - - N-4 methylation of cytosine
MDIBLFOF_01870 5.46e-170 - - - KL - - - DEAD-like helicases superfamily
MDIBLFOF_01871 2.08e-45 - - - V - - - HNH endonuclease
MDIBLFOF_01874 8e-63 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MDIBLFOF_01879 1.27e-24 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
MDIBLFOF_01881 5.55e-102 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
MDIBLFOF_01882 6.42e-112 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
MDIBLFOF_01883 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
MDIBLFOF_01884 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat
MDIBLFOF_01885 1.42e-172 - - - S - - - HAD hydrolase, family IA, variant 3
MDIBLFOF_01887 1.05e-161 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MDIBLFOF_01888 2.05e-224 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDIBLFOF_01889 1.6e-83 - - - - - - - -
MDIBLFOF_01890 1.68e-138 - - - - - - - -
MDIBLFOF_01893 8.83e-220 - - - S - - - Prophage endopeptidase tail
MDIBLFOF_01894 1.98e-89 - - - S - - - phage tail
MDIBLFOF_01895 1.02e-95 - - - NT - - - phage tail tape measure protein
MDIBLFOF_01897 1.62e-36 - - - - - - - -
MDIBLFOF_01898 7.03e-77 - - - N - - - domain, Protein
MDIBLFOF_01901 3.58e-40 - - - - - - - -
MDIBLFOF_01902 5.41e-60 - - - S - - - Phage protein Gp19/Gp15/Gp42
MDIBLFOF_01904 2.32e-188 - - - V - - - Phage capsid family
MDIBLFOF_01905 4.57e-71 - - - - - - - -
MDIBLFOF_01910 1.12e-284 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDIBLFOF_01911 9.87e-70 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDIBLFOF_01912 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
MDIBLFOF_01913 1.13e-223 - - - S - - - Protein conserved in bacteria
MDIBLFOF_01915 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MDIBLFOF_01916 1.8e-79 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MDIBLFOF_01917 2.45e-61 - - - - - - - -
MDIBLFOF_01918 3.27e-183 nfrA - - C - - - Nitroreductase family
MDIBLFOF_01919 9.49e-90 - - - S - - - Protein of unknown function (DUF4235)
MDIBLFOF_01920 1.02e-171 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
MDIBLFOF_01923 3.2e-242 - - - K - - - Psort location Cytoplasmic, score
MDIBLFOF_01924 0.0 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
MDIBLFOF_01925 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MDIBLFOF_01926 8.46e-88 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDIBLFOF_01929 2.65e-250 - - - I - - - PAP2 superfamily
MDIBLFOF_01930 0.0 - - - M - - - PA domain
MDIBLFOF_01931 6.24e-180 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
MDIBLFOF_01934 2.82e-72 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MDIBLFOF_01935 0.0 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
MDIBLFOF_01936 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
MDIBLFOF_01937 6.69e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MDIBLFOF_01938 4.41e-187 - - - U - - - Relaxase mobilization nuclease domain protein
MDIBLFOF_01939 1.17e-42 - - - S - - - Psort location Cytoplasmic, score 8.96
MDIBLFOF_01940 1.85e-62 - - - S - - - Psort location Cytoplasmic, score 8.96
MDIBLFOF_01941 3.47e-205 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family
MDIBLFOF_01942 1.59e-157 - - - S - - - Psort location Cytoplasmic, score 8.96
MDIBLFOF_01943 1.38e-33 - - - - - - - -
MDIBLFOF_01945 4.64e-83 - - - S - - - SPP1 phage holin

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)