ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HPEIFLPB_00001 7.74e-24 - - - M - - - Belongs to the glycosyl hydrolase 30 family
HPEIFLPB_00002 2.2e-244 - - - C - - - Aldo/keto reductase family
HPEIFLPB_00003 3.28e-57 - - - S - - - Protein of unknown function (DUF1778)
HPEIFLPB_00004 7.47e-123 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HPEIFLPB_00005 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HPEIFLPB_00006 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HPEIFLPB_00007 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
HPEIFLPB_00008 3.03e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HPEIFLPB_00009 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
HPEIFLPB_00010 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
HPEIFLPB_00011 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
HPEIFLPB_00012 6.15e-127 - - - S - - - GtrA-like protein
HPEIFLPB_00013 0.0 - - - EGP - - - Major Facilitator Superfamily
HPEIFLPB_00014 6.42e-161 - - - G - - - Phosphoglycerate mutase family
HPEIFLPB_00015 5.92e-193 - - - - - - - -
HPEIFLPB_00016 8.28e-178 - - - P - - - Binding-protein-dependent transport system inner membrane component
HPEIFLPB_00017 5.05e-258 - - - P - - - NMT1/THI5 like
HPEIFLPB_00018 1.07e-155 - - - S - - - HAD hydrolase, family IA, variant 3
HPEIFLPB_00020 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPEIFLPB_00021 5.89e-124 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HPEIFLPB_00022 1.54e-84 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HPEIFLPB_00025 1.45e-315 - - - S - - - Calcineurin-like phosphoesterase
HPEIFLPB_00026 6.48e-179 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
HPEIFLPB_00027 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPEIFLPB_00028 3.31e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPEIFLPB_00029 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
HPEIFLPB_00031 1.37e-248 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HPEIFLPB_00032 5.04e-279 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
HPEIFLPB_00033 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPEIFLPB_00034 1.05e-292 - - - G - - - Transmembrane secretion effector
HPEIFLPB_00035 5.9e-170 - - - K - - - Bacterial regulatory proteins, tetR family
HPEIFLPB_00036 2.12e-187 - - - - - - - -
HPEIFLPB_00037 1.43e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPEIFLPB_00038 1.23e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPEIFLPB_00039 4.41e-223 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
HPEIFLPB_00040 1.99e-240 - - - - - - - -
HPEIFLPB_00041 8.35e-232 - - - - - - - -
HPEIFLPB_00042 6.2e-215 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
HPEIFLPB_00043 1.65e-153 - - - S - - - CYTH
HPEIFLPB_00045 2.41e-236 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
HPEIFLPB_00046 9.69e-25 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 carboxylic acid catabolic process
HPEIFLPB_00047 1.24e-79 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
HPEIFLPB_00048 3.31e-186 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
HPEIFLPB_00050 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
HPEIFLPB_00051 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
HPEIFLPB_00052 1.08e-227 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HPEIFLPB_00053 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HPEIFLPB_00054 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPEIFLPB_00055 5.94e-107 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPEIFLPB_00056 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HPEIFLPB_00057 6.26e-305 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HPEIFLPB_00058 1.3e-237 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPEIFLPB_00059 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
HPEIFLPB_00060 3.3e-86 - - - - - - - -
HPEIFLPB_00061 6.44e-75 - - - - - - - -
HPEIFLPB_00062 2.26e-210 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_00063 0.0 - - - V - - - Efflux ABC transporter, permease protein
HPEIFLPB_00064 9.55e-215 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HPEIFLPB_00065 1.41e-304 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HPEIFLPB_00066 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
HPEIFLPB_00067 1.44e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HPEIFLPB_00068 2.12e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
HPEIFLPB_00069 7.66e-275 - - - K - - - Psort location Cytoplasmic, score
HPEIFLPB_00070 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPEIFLPB_00071 6.1e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPEIFLPB_00072 2.89e-294 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
HPEIFLPB_00074 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPEIFLPB_00075 2.53e-147 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HPEIFLPB_00076 1.27e-221 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HPEIFLPB_00077 1.38e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HPEIFLPB_00078 5.79e-278 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HPEIFLPB_00079 1.73e-253 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HPEIFLPB_00080 0.0 - 3.2.1.97 GH101 G ko:K17624 - ko00000,ko01000 Glycosyl hydrolase 101 beta sandwich domain
HPEIFLPB_00081 5.34e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPEIFLPB_00082 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HPEIFLPB_00083 5.79e-167 - - - - - - - -
HPEIFLPB_00084 1.82e-173 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
HPEIFLPB_00085 3.66e-57 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
HPEIFLPB_00086 6.47e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HPEIFLPB_00087 7.91e-111 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HPEIFLPB_00088 1.51e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPEIFLPB_00089 2.34e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HPEIFLPB_00092 9.21e-52 - - - S - - - Parallel beta-helix repeats
HPEIFLPB_00093 5.3e-97 - - - E - - - Domain of unknown function (DUF5011)
HPEIFLPB_00096 3.99e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HPEIFLPB_00097 1.36e-177 - - - M - - - Protein of unknown function (DUF3152)
HPEIFLPB_00098 7.29e-238 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HPEIFLPB_00099 5.02e-190 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HPEIFLPB_00100 2.45e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
HPEIFLPB_00101 0.0 - - - M - - - domain protein
HPEIFLPB_00102 9.91e-62 - - - M - - - LPXTG cell wall anchor motif
HPEIFLPB_00103 8.42e-262 - - - M - - - LPXTG cell wall anchor motif
HPEIFLPB_00104 1.26e-268 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HPEIFLPB_00105 9.95e-183 - - - S - - - Domain of unknown function (DUF4854)
HPEIFLPB_00106 2.84e-199 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
HPEIFLPB_00108 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPEIFLPB_00109 2.97e-169 - - - M - - - Mechanosensitive ion channel
HPEIFLPB_00110 1.51e-153 - - - K - - - Bacterial regulatory proteins, tetR family
HPEIFLPB_00111 3.35e-307 - - - S - - - Psort location Cytoplasmic, score 8.87
HPEIFLPB_00112 2.9e-296 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
HPEIFLPB_00113 9.29e-110 - - - M - - - Belongs to the glycosyl hydrolase 28 family
HPEIFLPB_00115 1.04e-59 - - - K - - - Transcriptional regulator
HPEIFLPB_00116 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HPEIFLPB_00117 0.00013 - - - TV ko:K05792 - ko00000 HNH endonuclease
HPEIFLPB_00118 1.75e-45 - - - - - - - -
HPEIFLPB_00123 3.18e-16 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
HPEIFLPB_00124 2.07e-301 - - - K - - - Helix-turn-helix XRE-family like proteins
HPEIFLPB_00125 1.77e-72 - - - L - - - RelB antitoxin
HPEIFLPB_00127 6.82e-170 - - - K - - - helix_turn_helix, mercury resistance
HPEIFLPB_00128 1.82e-310 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HPEIFLPB_00131 1.28e-254 - - - G - - - pfkB family carbohydrate kinase
HPEIFLPB_00132 7.42e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
HPEIFLPB_00133 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
HPEIFLPB_00134 1.17e-276 steT - - E ko:K03294 - ko00000 amino acid
HPEIFLPB_00137 0.0 - - - - - - - -
HPEIFLPB_00138 0.0 - - - U ko:K06956 - ko00000 Sodium:dicarboxylate symporter family
HPEIFLPB_00139 2.78e-158 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
HPEIFLPB_00140 7.85e-139 - - - S ko:K07078 - ko00000 Nitroreductase family
HPEIFLPB_00141 9.18e-109 - - - O - - - Hsp20/alpha crystallin family
HPEIFLPB_00142 4.27e-227 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HPEIFLPB_00143 3.22e-139 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPEIFLPB_00144 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HPEIFLPB_00145 2.4e-80 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HPEIFLPB_00146 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HPEIFLPB_00147 4.74e-132 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HPEIFLPB_00148 1.35e-282 - - - S - - - Endonuclease/Exonuclease/phosphatase family
HPEIFLPB_00149 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPEIFLPB_00150 4.14e-212 - - - P - - - Cation efflux family
HPEIFLPB_00151 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HPEIFLPB_00152 8.06e-175 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
HPEIFLPB_00153 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
HPEIFLPB_00154 1.04e-76 - - - S - - - Protein of unknown function (DUF3039)
HPEIFLPB_00155 4.42e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPEIFLPB_00156 3.51e-183 - - - - - - - -
HPEIFLPB_00157 5.11e-146 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HPEIFLPB_00158 2.72e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HPEIFLPB_00159 1.56e-179 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPEIFLPB_00160 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
HPEIFLPB_00161 1.26e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
HPEIFLPB_00164 1.4e-314 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPEIFLPB_00165 6.69e-173 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HPEIFLPB_00166 8.02e-152 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPEIFLPB_00167 1.88e-226 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
HPEIFLPB_00170 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HPEIFLPB_00171 2.09e-272 - - - - - - - -
HPEIFLPB_00173 6.19e-263 - - - - - - - -
HPEIFLPB_00175 7.52e-157 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
HPEIFLPB_00176 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
HPEIFLPB_00177 1.13e-29 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
HPEIFLPB_00178 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_00179 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_00180 8.57e-222 - - - K - - - Putative sugar-binding domain
HPEIFLPB_00181 1.46e-283 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HPEIFLPB_00182 0.0 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HPEIFLPB_00183 3.12e-220 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
HPEIFLPB_00184 8.39e-167 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
HPEIFLPB_00185 2.33e-81 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPEIFLPB_00186 2e-199 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HPEIFLPB_00187 6.64e-170 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPEIFLPB_00188 2.17e-267 - - - K - - - helix_turn _helix lactose operon repressor
HPEIFLPB_00189 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HPEIFLPB_00190 8.26e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HPEIFLPB_00191 2.33e-143 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HPEIFLPB_00193 1.32e-217 - - - G - - - Glycosyl hydrolases family 43
HPEIFLPB_00194 5.11e-133 - - - G - - - Glycosyl hydrolases family 43
HPEIFLPB_00195 1.19e-259 - - - K - - - helix_turn _helix lactose operon repressor
HPEIFLPB_00196 5.8e-16 - - - E - - - Domain of unknown function (DUF5011)
HPEIFLPB_00197 5.17e-218 - - - S - - - Oxidoreductase, aldo keto reductase family protein
HPEIFLPB_00198 5.2e-173 - - - L - - - Protein of unknown function (DUF1524)
HPEIFLPB_00199 4.16e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HPEIFLPB_00200 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
HPEIFLPB_00201 1.66e-301 - - - - - - - -
HPEIFLPB_00202 5.86e-229 - - - S ko:K21688 - ko00000 G5
HPEIFLPB_00203 2.57e-78 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
HPEIFLPB_00204 8.16e-154 - - - F - - - Domain of unknown function (DUF4916)
HPEIFLPB_00205 2.08e-205 - - - I - - - Alpha/beta hydrolase family
HPEIFLPB_00207 0.0 - - - S - - - L,D-transpeptidase catalytic domain
HPEIFLPB_00208 2.17e-93 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HPEIFLPB_00209 0.0 - - - S - - - Uncharacterized conserved protein (DUF2183)
HPEIFLPB_00210 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
HPEIFLPB_00211 3.62e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HPEIFLPB_00212 8.97e-151 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
HPEIFLPB_00213 4.67e-173 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HPEIFLPB_00214 0.0 pon1 - - M - - - Transglycosylase
HPEIFLPB_00215 1.5e-277 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
HPEIFLPB_00216 4.9e-288 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HPEIFLPB_00217 1.2e-179 - - - K - - - DeoR C terminal sensor domain
HPEIFLPB_00218 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
HPEIFLPB_00219 8.03e-295 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
HPEIFLPB_00220 5.39e-308 - - - EGP - - - Sugar (and other) transporter
HPEIFLPB_00221 3.23e-58 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HPEIFLPB_00222 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
HPEIFLPB_00223 2.18e-139 - - - - - - - -
HPEIFLPB_00225 5.27e-156 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPEIFLPB_00227 1.95e-48 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
HPEIFLPB_00228 6.36e-38 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G ko:K01186,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 xyloglucan:xyloglucosyl transferase activity
HPEIFLPB_00229 3.15e-236 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
HPEIFLPB_00230 1.12e-143 - - - - - - - -
HPEIFLPB_00231 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPEIFLPB_00232 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPEIFLPB_00233 6.53e-125 - - - T - - - Forkhead associated domain
HPEIFLPB_00234 1.48e-97 - - - B - - - Belongs to the OprB family
HPEIFLPB_00235 4.74e-211 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
HPEIFLPB_00236 0.0 - - - E - - - Transglutaminase-like superfamily
HPEIFLPB_00237 1.92e-300 - - - S - - - Protein of unknown function DUF58
HPEIFLPB_00238 0.0 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HPEIFLPB_00239 0.0 - - - S - - - Fibronectin type 3 domain
HPEIFLPB_00240 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HPEIFLPB_00241 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
HPEIFLPB_00242 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
HPEIFLPB_00243 8.82e-207 - - - K - - - -acetyltransferase
HPEIFLPB_00244 3.52e-316 - - - G - - - Major Facilitator Superfamily
HPEIFLPB_00245 3.22e-33 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HPEIFLPB_00246 3e-47 - - - L - - - Transposase
HPEIFLPB_00247 1.16e-169 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPEIFLPB_00248 2.93e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPEIFLPB_00249 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPEIFLPB_00250 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
HPEIFLPB_00251 0.0 vpr - - O - - - Subtilase family
HPEIFLPB_00252 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPEIFLPB_00253 6.43e-160 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPEIFLPB_00254 0.0 - - - S - - - zinc finger
HPEIFLPB_00255 2.43e-129 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HPEIFLPB_00256 7.65e-293 aspB 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class-V
HPEIFLPB_00257 2.21e-47 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
HPEIFLPB_00258 7.96e-170 tmp1 - - S - - - Domain of unknown function (DUF4391)
HPEIFLPB_00259 1.34e-183 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
HPEIFLPB_00260 0.0 - - - OP - - - Sulfurtransferase TusA
HPEIFLPB_00261 3.88e-233 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HPEIFLPB_00262 4.35e-05 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HPEIFLPB_00264 1.51e-258 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
HPEIFLPB_00265 1.47e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPEIFLPB_00266 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPEIFLPB_00267 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
HPEIFLPB_00268 5.91e-179 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPEIFLPB_00270 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
HPEIFLPB_00271 3.9e-213 - - - - - - - -
HPEIFLPB_00272 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
HPEIFLPB_00273 0.0 - - - M - - - Parallel beta-helix repeats
HPEIFLPB_00275 4.46e-118 - - - K - - - MarR family
HPEIFLPB_00276 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HPEIFLPB_00277 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HPEIFLPB_00278 2.26e-220 - - - S - - - Patatin-like phospholipase
HPEIFLPB_00279 2.24e-195 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HPEIFLPB_00280 7.32e-216 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HPEIFLPB_00281 4.82e-147 - - - S - - - Vitamin K epoxide reductase
HPEIFLPB_00282 2.09e-212 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
HPEIFLPB_00283 9.31e-44 - - - S - - - Protein of unknown function (DUF3107)
HPEIFLPB_00284 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
HPEIFLPB_00285 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HPEIFLPB_00286 0.0 - - - S - - - Zincin-like metallopeptidase
HPEIFLPB_00287 2.91e-193 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HPEIFLPB_00288 2.24e-86 - - - S - - - Protein of unknown function (DUF3052)
HPEIFLPB_00289 1.96e-248 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPEIFLPB_00290 1.52e-81 - - - S - - - Thiamine-binding protein
HPEIFLPB_00291 7.27e-211 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HPEIFLPB_00292 3.43e-291 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
HPEIFLPB_00293 1.62e-110 - - - - - - - -
HPEIFLPB_00294 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HPEIFLPB_00295 1.75e-202 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPEIFLPB_00296 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
HPEIFLPB_00297 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
HPEIFLPB_00298 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
HPEIFLPB_00299 4.69e-314 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPEIFLPB_00300 8.03e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPEIFLPB_00301 9.4e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPEIFLPB_00302 1.35e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
HPEIFLPB_00303 3.32e-191 - - - V - - - DivIVA protein
HPEIFLPB_00304 4.6e-148 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPEIFLPB_00305 7.68e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HPEIFLPB_00307 1.25e-82 - - - - - - - -
HPEIFLPB_00308 3.72e-220 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HPEIFLPB_00309 5.51e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPEIFLPB_00310 3.39e-298 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
HPEIFLPB_00311 4.29e-203 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
HPEIFLPB_00312 1.52e-269 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
HPEIFLPB_00313 1.38e-103 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPEIFLPB_00314 3.17e-187 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
HPEIFLPB_00315 5.45e-60 - - - - - - - -
HPEIFLPB_00316 8.09e-31 - - - - - - - -
HPEIFLPB_00318 1.34e-311 - - - NU - - - Tfp pilus assembly protein FimV
HPEIFLPB_00319 1.52e-282 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HPEIFLPB_00320 4.85e-299 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HPEIFLPB_00321 0.0 - - - I - - - acetylesterase activity
HPEIFLPB_00322 1.96e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HPEIFLPB_00323 1.03e-197 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPEIFLPB_00324 1.36e-244 - - - S - - - Domain of unknown function (DUF1963)
HPEIFLPB_00325 1.2e-19 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HPEIFLPB_00326 4.54e-53 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HPEIFLPB_00327 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
HPEIFLPB_00328 2.41e-163 - - - S - - - zinc-ribbon domain
HPEIFLPB_00329 1.34e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
HPEIFLPB_00330 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
HPEIFLPB_00331 0.000563 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPEIFLPB_00333 4.31e-259 - - - K - - - WYL domain
HPEIFLPB_00334 5.5e-199 - - - S - - - Aldo/keto reductase family
HPEIFLPB_00335 8.97e-223 dkgV - - C - - - Aldo/keto reductase family
HPEIFLPB_00336 6.13e-100 - - - S - - - Domain of unknown function (DUF4186)
HPEIFLPB_00339 2.68e-232 - - - S - - - Protein conserved in bacteria
HPEIFLPB_00340 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPEIFLPB_00341 1.85e-285 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPEIFLPB_00342 1.08e-145 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
HPEIFLPB_00343 3.59e-151 - - - - - - - -
HPEIFLPB_00344 5.49e-156 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPEIFLPB_00345 8.32e-168 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
HPEIFLPB_00346 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
HPEIFLPB_00347 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HPEIFLPB_00348 0.0 - - - S - - - Domain of unknown function (DUF5067)
HPEIFLPB_00349 2e-75 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator Superfamily
HPEIFLPB_00350 1.03e-242 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HPEIFLPB_00351 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
HPEIFLPB_00352 5.07e-157 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
HPEIFLPB_00353 8.3e-82 - - - - - - - -
HPEIFLPB_00354 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPEIFLPB_00355 1.96e-226 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HPEIFLPB_00356 6.43e-212 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPEIFLPB_00357 3.03e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPEIFLPB_00358 1.19e-65 - - - M - - - Lysin motif
HPEIFLPB_00359 2.55e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPEIFLPB_00360 1.37e-291 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPEIFLPB_00361 0.0 - - - L - - - DNA helicase
HPEIFLPB_00362 3.61e-117 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HPEIFLPB_00363 1.25e-261 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPEIFLPB_00364 1.96e-97 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HPEIFLPB_00365 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
HPEIFLPB_00366 2.48e-231 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPEIFLPB_00367 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPEIFLPB_00368 8.76e-261 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPEIFLPB_00369 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPEIFLPB_00370 4.49e-297 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
HPEIFLPB_00371 9.01e-276 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPEIFLPB_00372 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HPEIFLPB_00373 5.86e-232 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
HPEIFLPB_00376 2.9e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPEIFLPB_00377 6.45e-302 - - - G - - - Major Facilitator Superfamily
HPEIFLPB_00378 2.87e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HPEIFLPB_00379 2.17e-285 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HPEIFLPB_00380 1.67e-169 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HPEIFLPB_00381 1.44e-276 - - - GK - - - ROK family
HPEIFLPB_00382 5.93e-196 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPEIFLPB_00383 6.26e-309 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
HPEIFLPB_00384 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HPEIFLPB_00385 5.3e-243 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_00386 3.74e-249 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_00387 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HPEIFLPB_00388 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
HPEIFLPB_00389 3.73e-126 - - - F - - - NUDIX domain
HPEIFLPB_00391 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
HPEIFLPB_00392 1.02e-299 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HPEIFLPB_00393 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HPEIFLPB_00394 1.46e-165 - 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HPEIFLPB_00395 3.61e-309 - 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp
HPEIFLPB_00396 2.77e-292 - 2.6.1.33 - M ko:K20429 - ko00000,ko01000 DegT/DnrJ/EryC1/StrS aminotransferase family
HPEIFLPB_00397 1.26e-244 - - - V - - - Acetyltransferase (GNAT) domain
HPEIFLPB_00398 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPEIFLPB_00399 5.75e-148 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HPEIFLPB_00400 3.22e-82 - - - - - - - -
HPEIFLPB_00401 6.49e-249 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HPEIFLPB_00402 1.13e-231 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HPEIFLPB_00404 6.06e-119 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPEIFLPB_00405 3.39e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPEIFLPB_00406 4.14e-173 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
HPEIFLPB_00407 2.74e-90 - - - S - - - Spermine/spermidine synthase domain
HPEIFLPB_00408 3.07e-137 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPEIFLPB_00409 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
HPEIFLPB_00410 5.46e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPEIFLPB_00411 2.79e-227 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
HPEIFLPB_00412 7.59e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HPEIFLPB_00413 9.32e-191 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPEIFLPB_00414 6.74e-126 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPEIFLPB_00415 5.17e-192 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
HPEIFLPB_00416 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HPEIFLPB_00417 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HPEIFLPB_00418 7.85e-210 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
HPEIFLPB_00419 3.57e-298 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
HPEIFLPB_00420 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
HPEIFLPB_00421 1.35e-111 - - - - - - - -
HPEIFLPB_00422 1.44e-253 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HPEIFLPB_00423 4.23e-245 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
HPEIFLPB_00424 2.67e-56 - - - - - - - -
HPEIFLPB_00425 1.73e-238 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HPEIFLPB_00426 4.8e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_00427 5.29e-212 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
HPEIFLPB_00428 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HPEIFLPB_00429 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HPEIFLPB_00430 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HPEIFLPB_00431 2.87e-215 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
HPEIFLPB_00432 2.66e-196 - - - S - - - Protein of unknown function (DUF3710)
HPEIFLPB_00433 3.77e-172 - - - S - - - Protein of unknown function (DUF3159)
HPEIFLPB_00434 1.9e-315 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPEIFLPB_00435 4.91e-144 - - - - - - - -
HPEIFLPB_00436 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HPEIFLPB_00437 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HPEIFLPB_00438 2.59e-212 - - - S - - - Protein conserved in bacteria
HPEIFLPB_00439 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
HPEIFLPB_00440 9.87e-70 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPEIFLPB_00441 9.27e-152 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPEIFLPB_00442 3.34e-61 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPEIFLPB_00443 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPEIFLPB_00444 3.86e-174 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HPEIFLPB_00445 1.29e-233 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPEIFLPB_00446 2.58e-176 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
HPEIFLPB_00447 2.38e-134 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
HPEIFLPB_00448 3.46e-237 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
HPEIFLPB_00449 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
HPEIFLPB_00450 1.98e-203 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
HPEIFLPB_00451 1.05e-28 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HPEIFLPB_00452 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HPEIFLPB_00453 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
HPEIFLPB_00454 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
HPEIFLPB_00455 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
HPEIFLPB_00456 0.0 - - - S - - - PGAP1-like protein
HPEIFLPB_00458 1.6e-117 - - - - - - - -
HPEIFLPB_00459 2.85e-198 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
HPEIFLPB_00460 1.86e-245 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
HPEIFLPB_00461 1.78e-121 - - - - - - - -
HPEIFLPB_00462 3.68e-231 - - - S - - - Protein of unknown function DUF58
HPEIFLPB_00463 7.07e-251 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HPEIFLPB_00464 1.29e-185 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPEIFLPB_00465 7.36e-106 - - - S - - - LytR cell envelope-related transcriptional attenuator
HPEIFLPB_00466 1.49e-58 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HPEIFLPB_00467 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPEIFLPB_00468 8.25e-53 - - - S - - - Proteins of 100 residues with WXG
HPEIFLPB_00469 7.36e-227 - - - - - - - -
HPEIFLPB_00470 1.75e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
HPEIFLPB_00471 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPEIFLPB_00472 1.23e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HPEIFLPB_00473 1.24e-259 - - - S - - - Protein of unknown function (DUF3027)
HPEIFLPB_00474 2.42e-237 uspA - - T - - - Belongs to the universal stress protein A family
HPEIFLPB_00475 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
HPEIFLPB_00479 5.26e-302 - - - S - - - Domain of Unknown Function (DUF349)
HPEIFLPB_00480 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
HPEIFLPB_00481 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HPEIFLPB_00482 8.44e-97 - - - K - - - helix_turn_helix, Lux Regulon
HPEIFLPB_00483 7.88e-121 - - - S - - - Aminoacyl-tRNA editing domain
HPEIFLPB_00484 5.87e-180 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
HPEIFLPB_00485 5.66e-194 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HPEIFLPB_00486 1.21e-143 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_00487 3.8e-252 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_00488 1.68e-253 - - - S - - - Polyphosphate kinase 2 (PPK2)
HPEIFLPB_00489 0.0 - - - L - - - DEAD DEAH box helicase
HPEIFLPB_00490 2.97e-137 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
HPEIFLPB_00491 9.65e-145 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
HPEIFLPB_00493 0.0 - - - EGP - - - Major Facilitator Superfamily
HPEIFLPB_00494 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPEIFLPB_00495 3.98e-135 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPEIFLPB_00497 5.43e-179 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HPEIFLPB_00498 3.37e-270 - - - E - - - Aminotransferase class I and II
HPEIFLPB_00499 3.64e-177 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_00500 1.13e-90 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HPEIFLPB_00501 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPEIFLPB_00502 0.0 - - - S - - - Tetratricopeptide repeat
HPEIFLPB_00503 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPEIFLPB_00504 2.75e-268 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HPEIFLPB_00505 1.43e-203 - - - S - - - Protein conserved in bacteria
HPEIFLPB_00506 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HPEIFLPB_00507 7.09e-181 - - - S - - - Domain of unknown function (DUF4191)
HPEIFLPB_00508 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPEIFLPB_00509 2.07e-134 - - - S - - - Protein of unknown function (DUF3043)
HPEIFLPB_00510 0.0 argE - - E - - - Peptidase dimerisation domain
HPEIFLPB_00511 6.77e-119 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
HPEIFLPB_00512 1.56e-190 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_00513 3.25e-252 - - - - - - - -
HPEIFLPB_00514 1.7e-298 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
HPEIFLPB_00515 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
HPEIFLPB_00516 2.04e-263 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPEIFLPB_00517 0.0 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPEIFLPB_00518 7.14e-276 - - - I ko:K13663 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
HPEIFLPB_00520 1.49e-164 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HPEIFLPB_00521 3.47e-252 - - - GM - - - GDP-mannose 4,6 dehydratase
HPEIFLPB_00522 1.2e-194 - - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HPEIFLPB_00523 1.97e-186 rfbB2 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HPEIFLPB_00524 9.1e-127 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HPEIFLPB_00525 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPEIFLPB_00526 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPEIFLPB_00527 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000,ko01007 chorismate binding enzyme
HPEIFLPB_00528 2.04e-194 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 - E ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 branched-chain-amino-acid transaminase activity
HPEIFLPB_00529 7.41e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPEIFLPB_00530 3.44e-130 - - - D - - - Septum formation initiator
HPEIFLPB_00531 2.55e-137 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
HPEIFLPB_00532 3.42e-233 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
HPEIFLPB_00534 1.26e-125 - - - - - - - -
HPEIFLPB_00535 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
HPEIFLPB_00536 8.53e-95 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
HPEIFLPB_00537 1.67e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPEIFLPB_00538 7.92e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
HPEIFLPB_00539 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPEIFLPB_00540 6.69e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HPEIFLPB_00541 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
HPEIFLPB_00542 0.0 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
HPEIFLPB_00543 2.82e-72 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HPEIFLPB_00544 0.0 - - - S - - - Glycosyl transferase, family 2
HPEIFLPB_00545 0.0 - - - - - - - -
HPEIFLPB_00546 1.05e-85 - - - S - - - Zincin-like metallopeptidase
HPEIFLPB_00547 2.33e-200 - - - T - - - Eukaryotic phosphomannomutase
HPEIFLPB_00548 2.3e-168 pyrE_1 - - S - - - Phosphoribosyl transferase domain
HPEIFLPB_00549 3.2e-93 umuD - - KT ko:K03503 - ko00000,ko01000,ko01002,ko03400 Peptidase S24-like
HPEIFLPB_00550 1.69e-258 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPEIFLPB_00551 9.32e-164 cseB - - T - - - Response regulator receiver domain protein
HPEIFLPB_00552 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPEIFLPB_00553 1.99e-131 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
HPEIFLPB_00554 2.56e-108 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HPEIFLPB_00555 6.17e-177 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HPEIFLPB_00556 1.15e-209 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_00557 1.55e-232 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
HPEIFLPB_00558 2.97e-211 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPEIFLPB_00559 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HPEIFLPB_00560 2.24e-139 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPEIFLPB_00561 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPEIFLPB_00562 4.13e-230 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
HPEIFLPB_00563 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
HPEIFLPB_00564 2e-141 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HPEIFLPB_00566 5.44e-161 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
HPEIFLPB_00567 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPEIFLPB_00568 5.39e-221 - - - L - - - NIF3 (NGG1p interacting factor 3)
HPEIFLPB_00569 3.4e-156 - - - L - - - NUDIX domain
HPEIFLPB_00570 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
HPEIFLPB_00571 1.62e-277 - - - - - - - -
HPEIFLPB_00573 6.39e-173 - - - L - - - Phage integrase family
HPEIFLPB_00574 9.85e-140 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
HPEIFLPB_00575 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPEIFLPB_00576 1.39e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPEIFLPB_00577 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
HPEIFLPB_00578 6.9e-158 - - - - - - - -
HPEIFLPB_00580 4.68e-91 - - - S - - - Protein of unknown function (DUF1294)
HPEIFLPB_00581 1.46e-37 - - - - - - - -
HPEIFLPB_00585 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HPEIFLPB_00586 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HPEIFLPB_00587 3.74e-243 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
HPEIFLPB_00588 4.91e-150 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
HPEIFLPB_00589 1.61e-155 - - - K - - - helix_turn_helix, Lux Regulon
HPEIFLPB_00590 4.86e-297 - - - T - - - Histidine kinase
HPEIFLPB_00591 2.51e-56 pacL 3.6.3.8, 3.6.3.9 - P ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 ATPase, P-type transporting, HAD superfamily, subfamily IC
HPEIFLPB_00592 2.32e-233 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_00593 2.77e-290 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HPEIFLPB_00594 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HPEIFLPB_00595 1.21e-26 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HPEIFLPB_00596 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HPEIFLPB_00597 8.46e-155 - - - L - - - Transposase and inactivated derivatives IS30 family
HPEIFLPB_00598 6.06e-151 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
HPEIFLPB_00599 6.72e-140 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HPEIFLPB_00600 1.38e-235 - - - - - - - -
HPEIFLPB_00601 2e-09 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
HPEIFLPB_00602 4.37e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HPEIFLPB_00603 1.94e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
HPEIFLPB_00604 5.06e-145 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPEIFLPB_00605 6.63e-52 - - - E - - - Branched-chain amino acid transport protein (AzlD)
HPEIFLPB_00606 1.27e-249 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HPEIFLPB_00607 9.52e-124 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
HPEIFLPB_00608 1.1e-164 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
HPEIFLPB_00609 4.99e-223 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPEIFLPB_00610 4.35e-94 - - - O - - - OsmC-like protein
HPEIFLPB_00611 1.31e-244 - - - T - - - Universal stress protein family
HPEIFLPB_00612 9.72e-153 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HPEIFLPB_00613 3.37e-228 - - - S - - - CHAP domain
HPEIFLPB_00614 4.28e-274 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPEIFLPB_00615 4.6e-53 - - - - - - - -
HPEIFLPB_00616 9.24e-288 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPEIFLPB_00617 9.33e-153 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HPEIFLPB_00618 3.69e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPEIFLPB_00619 2.89e-224 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HPEIFLPB_00620 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HPEIFLPB_00622 7.45e-278 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
HPEIFLPB_00623 0.0 - - - S - - - Domain of unknown function (DUF4037)
HPEIFLPB_00624 9.55e-146 - - - S - - - Protein of unknown function (DUF4125)
HPEIFLPB_00625 4.08e-199 - - - - - - - -
HPEIFLPB_00626 0.0 pspC - - KT - - - PspC domain
HPEIFLPB_00627 0.0 tcsS3 - - KT - - - PspC domain
HPEIFLPB_00628 1.18e-162 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
HPEIFLPB_00629 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPEIFLPB_00631 5.83e-181 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HPEIFLPB_00632 7.54e-240 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
HPEIFLPB_00633 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPEIFLPB_00634 4.52e-123 - - - - - - - -
HPEIFLPB_00636 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
HPEIFLPB_00638 2.32e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPEIFLPB_00639 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
HPEIFLPB_00640 1.37e-271 - - - I - - - Diacylglycerol kinase catalytic domain
HPEIFLPB_00641 5.06e-198 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HPEIFLPB_00642 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
HPEIFLPB_00643 8.64e-05 - - - O ko:K18546 - ko00000,ko01000,ko01002 Peptidase s1 and s6 chymotrypsin hap
HPEIFLPB_00644 5.93e-60 - - - M - - - Spy0128-like isopeptide containing domain
HPEIFLPB_00645 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HPEIFLPB_00646 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPEIFLPB_00647 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
HPEIFLPB_00648 1.77e-260 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPEIFLPB_00649 1.28e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPEIFLPB_00650 5.18e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
HPEIFLPB_00651 6.9e-142 - - - - - - - -
HPEIFLPB_00652 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPEIFLPB_00653 1.78e-304 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
HPEIFLPB_00654 3.18e-299 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPEIFLPB_00655 8.76e-124 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPEIFLPB_00656 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPEIFLPB_00657 1.16e-241 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HPEIFLPB_00658 6.58e-227 - - - - - - - -
HPEIFLPB_00659 4.97e-186 tnp3503b - - L - - - Transposase and inactivated derivatives
HPEIFLPB_00661 5.51e-199 - - - E - - - Transglutaminase/protease-like homologues
HPEIFLPB_00662 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
HPEIFLPB_00663 6.02e-221 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPEIFLPB_00664 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
HPEIFLPB_00665 3.77e-95 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HPEIFLPB_00666 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPEIFLPB_00667 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPEIFLPB_00668 6.96e-83 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPEIFLPB_00669 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HPEIFLPB_00670 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPEIFLPB_00671 2.77e-128 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPEIFLPB_00672 9.36e-317 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPEIFLPB_00673 1.51e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HPEIFLPB_00674 1.46e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
HPEIFLPB_00675 2.04e-149 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPEIFLPB_00676 1.53e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPEIFLPB_00677 2.69e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPEIFLPB_00678 9.65e-91 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPEIFLPB_00679 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPEIFLPB_00680 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPEIFLPB_00681 9.32e-70 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPEIFLPB_00682 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPEIFLPB_00683 9.4e-57 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPEIFLPB_00684 6.77e-51 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HPEIFLPB_00685 2.71e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPEIFLPB_00686 2.73e-161 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPEIFLPB_00687 2.21e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPEIFLPB_00688 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPEIFLPB_00689 1.15e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPEIFLPB_00690 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPEIFLPB_00691 1.34e-154 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HPEIFLPB_00692 6.65e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPEIFLPB_00693 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HPEIFLPB_00694 1.24e-129 - - - S - - - YwiC-like protein
HPEIFLPB_00695 1.36e-213 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HPEIFLPB_00696 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HPEIFLPB_00697 4.31e-298 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HPEIFLPB_00698 1.83e-225 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
HPEIFLPB_00699 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
HPEIFLPB_00700 1.71e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HPEIFLPB_00701 2.64e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPEIFLPB_00702 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
HPEIFLPB_00703 1.25e-156 - - - - - - - -
HPEIFLPB_00704 5.69e-147 yigZ - - S - - - Uncharacterized protein family UPF0029
HPEIFLPB_00705 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
HPEIFLPB_00707 2.66e-307 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPEIFLPB_00708 5.74e-285 dapC - - E - - - Aminotransferase class I and II
HPEIFLPB_00709 3.55e-81 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
HPEIFLPB_00710 5.48e-280 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HPEIFLPB_00711 2.71e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
HPEIFLPB_00715 1.01e-75 - - - KLT - - - Associated with various cellular activities
HPEIFLPB_00716 1.49e-171 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HPEIFLPB_00717 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPEIFLPB_00718 3.16e-273 - - - - - - - -
HPEIFLPB_00719 1.2e-191 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HPEIFLPB_00720 5.69e-154 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
HPEIFLPB_00721 1.88e-51 - - - S - - - Putative regulatory protein
HPEIFLPB_00722 2.46e-140 - - - NO - - - SAF
HPEIFLPB_00723 1.66e-55 - - - - - - - -
HPEIFLPB_00724 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
HPEIFLPB_00725 0.0 - - - T - - - Forkhead associated domain
HPEIFLPB_00727 5.13e-61 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPEIFLPB_00728 5.06e-115 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPEIFLPB_00729 2.95e-234 xynB2 1.1.1.169 - E ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 lipolytic protein G-D-S-L family
HPEIFLPB_00730 0.0 - - - G - - - BNR repeat-like domain
HPEIFLPB_00732 5.92e-313 - - - S ko:K06901 - ko00000,ko02000 Permease family
HPEIFLPB_00734 2.3e-172 - - - S - - - Protein conserved in bacteria
HPEIFLPB_00735 1.29e-189 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPEIFLPB_00736 6.61e-234 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HPEIFLPB_00737 8.51e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HPEIFLPB_00738 1.71e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
HPEIFLPB_00739 1.33e-165 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HPEIFLPB_00740 1.05e-310 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HPEIFLPB_00741 6.31e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPEIFLPB_00742 5.96e-304 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPEIFLPB_00743 2.63e-142 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HPEIFLPB_00744 1.05e-310 - - - EGP - - - Major Facilitator Superfamily
HPEIFLPB_00745 3.97e-277 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPEIFLPB_00746 6.11e-233 - - - L - - - Excalibur calcium-binding domain
HPEIFLPB_00747 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HPEIFLPB_00748 9.13e-119 - - - D - - - nuclear chromosome segregation
HPEIFLPB_00749 2.61e-163 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPEIFLPB_00750 9.04e-186 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HPEIFLPB_00751 2.74e-241 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
HPEIFLPB_00752 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
HPEIFLPB_00753 8.08e-121 - - - L - - - Transposase and inactivated derivatives IS30 family
HPEIFLPB_00754 6.85e-214 - - - C - - - Oxidoreductase, aldo keto reductase family protein
HPEIFLPB_00755 1.26e-55 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HPEIFLPB_00756 3.47e-128 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HPEIFLPB_00757 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPEIFLPB_00758 1.03e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPEIFLPB_00759 1.22e-91 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
HPEIFLPB_00760 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HPEIFLPB_00761 1.85e-123 lemA - - S ko:K03744 - ko00000 LemA family
HPEIFLPB_00762 4.06e-146 xylR - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
HPEIFLPB_00763 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HPEIFLPB_00764 8.32e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPEIFLPB_00765 3.14e-155 - - - - - - - -
HPEIFLPB_00766 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
HPEIFLPB_00767 8.37e-10 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
HPEIFLPB_00769 4.39e-209 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
HPEIFLPB_00770 6.8e-129 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPEIFLPB_00771 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
HPEIFLPB_00772 0.0 pccB - - I - - - Carboxyl transferase domain
HPEIFLPB_00773 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HPEIFLPB_00774 2.5e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HPEIFLPB_00775 4.75e-196 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
HPEIFLPB_00776 0.0 - - - - - - - -
HPEIFLPB_00777 8.27e-187 - - - QT - - - PucR C-terminal helix-turn-helix domain
HPEIFLPB_00778 3.84e-169 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HPEIFLPB_00779 1.39e-66 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HPEIFLPB_00780 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPEIFLPB_00781 2.73e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPEIFLPB_00782 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPEIFLPB_00783 2.31e-191 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPEIFLPB_00784 7.5e-98 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPEIFLPB_00785 1.21e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPEIFLPB_00787 3.54e-188 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HPEIFLPB_00788 1.98e-263 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HPEIFLPB_00790 1.11e-59 - - - - - - - -
HPEIFLPB_00791 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
HPEIFLPB_00792 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HPEIFLPB_00793 1.13e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HPEIFLPB_00795 2.85e-134 mntP - - P - - - Probably functions as a manganese efflux pump
HPEIFLPB_00796 5.6e-170 - - - - - - - -
HPEIFLPB_00797 4.39e-172 glnR - - KT - - - Transcriptional regulatory protein, C terminal
HPEIFLPB_00798 8.16e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPEIFLPB_00799 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HPEIFLPB_00800 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPEIFLPB_00801 0.0 - - - S - - - domain protein
HPEIFLPB_00802 9.37e-96 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
HPEIFLPB_00803 8.96e-117 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
HPEIFLPB_00804 5.05e-299 - 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HPEIFLPB_00805 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPEIFLPB_00806 0.0 - - - H - - - Flavin containing amine oxidoreductase
HPEIFLPB_00807 1.32e-68 - - - S - - - Protein of unknown function (DUF2469)
HPEIFLPB_00808 2.28e-250 - - - J - - - Acetyltransferase (GNAT) domain
HPEIFLPB_00809 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPEIFLPB_00810 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPEIFLPB_00811 3.33e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPEIFLPB_00812 3.27e-19 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HPEIFLPB_00813 5.5e-54 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HPEIFLPB_00814 4.57e-212 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
HPEIFLPB_00815 7.09e-164 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPEIFLPB_00816 1.45e-297 rmuC - - S ko:K09760 - ko00000 RmuC family
HPEIFLPB_00817 6.68e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
HPEIFLPB_00818 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HPEIFLPB_00819 0.0 - - - S ko:K03688 - ko00000 ABC1 family
HPEIFLPB_00820 3.15e-44 - - - S - - - granule-associated protein
HPEIFLPB_00821 1.02e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HPEIFLPB_00822 0.0 murE - - M - - - Domain of unknown function (DUF1727)
HPEIFLPB_00823 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HPEIFLPB_00824 0.0 dinF - - V - - - MatE
HPEIFLPB_00825 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
HPEIFLPB_00826 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
HPEIFLPB_00827 8.54e-305 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
HPEIFLPB_00828 6.66e-281 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPEIFLPB_00830 1.17e-172 icaR - - K - - - Bacterial regulatory proteins, tetR family
HPEIFLPB_00831 6.85e-255 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
HPEIFLPB_00832 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
HPEIFLPB_00833 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
HPEIFLPB_00835 8.82e-25 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HPEIFLPB_00836 5.96e-91 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HPEIFLPB_00837 2.35e-106 - - - - - - - -
HPEIFLPB_00838 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HPEIFLPB_00839 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HPEIFLPB_00840 1.27e-103 - - - K - - - Winged helix DNA-binding domain
HPEIFLPB_00841 4.77e-91 - - - E - - - IrrE N-terminal-like domain
HPEIFLPB_00843 3.89e-206 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPEIFLPB_00844 1.53e-305 - - - S - - - Putative ABC-transporter type IV
HPEIFLPB_00845 2.24e-103 - - - - - - - -
HPEIFLPB_00846 5.67e-36 - - - Q - - - phosphatase activity
HPEIFLPB_00847 6.94e-11 - - - S - - - haloacid dehalogenase-like hydrolase
HPEIFLPB_00848 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
HPEIFLPB_00849 1.29e-66 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HPEIFLPB_00850 1.2e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HPEIFLPB_00851 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEIFLPB_00852 1.13e-86 - - - S - - - haloacid dehalogenase-like hydrolase
HPEIFLPB_00853 1.5e-167 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
HPEIFLPB_00854 8.08e-103 - - - S - - - FMN_bind
HPEIFLPB_00855 7.76e-191 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPEIFLPB_00856 3.74e-275 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HPEIFLPB_00857 7.59e-288 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HPEIFLPB_00858 1.76e-295 - - - S - - - Predicted membrane protein (DUF2318)
HPEIFLPB_00859 2.37e-146 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
HPEIFLPB_00860 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
HPEIFLPB_00861 5.86e-31 - - - G - - - MFS/sugar transport protein
HPEIFLPB_00862 2.38e-255 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPEIFLPB_00863 3.94e-48 - - - S - - - Fic/DOC family
HPEIFLPB_00865 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPEIFLPB_00866 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HPEIFLPB_00867 8.04e-257 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPEIFLPB_00868 3.65e-273 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HPEIFLPB_00869 2.08e-158 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPEIFLPB_00870 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPEIFLPB_00871 1.87e-250 - - - I - - - PAP2 superfamily
HPEIFLPB_00872 0.0 - - - M - - - PA domain
HPEIFLPB_00873 6.24e-180 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
HPEIFLPB_00874 1.27e-295 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HPEIFLPB_00875 0.0 pbp5 - - M - - - Transglycosylase
HPEIFLPB_00876 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPEIFLPB_00877 0.0 - - - S - - - Calcineurin-like phosphoesterase
HPEIFLPB_00878 1.67e-19 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
HPEIFLPB_00879 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
HPEIFLPB_00880 1.46e-147 - - - - - - - -
HPEIFLPB_00881 7.91e-271 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPEIFLPB_00883 1.42e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
HPEIFLPB_00884 2.29e-176 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HPEIFLPB_00885 1.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPEIFLPB_00886 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
HPEIFLPB_00887 8.93e-272 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
HPEIFLPB_00888 3.62e-73 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
HPEIFLPB_00889 1.13e-54 - - - S - - - Protein of unknown function (DUF4244)
HPEIFLPB_00890 3.1e-111 - - - NU - - - Type II secretion system (T2SS), protein F
HPEIFLPB_00891 6.16e-156 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
HPEIFLPB_00892 6.74e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
HPEIFLPB_00893 1.34e-196 - - - D - - - bacterial-type flagellum organization
HPEIFLPB_00895 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPEIFLPB_00896 5.71e-257 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
HPEIFLPB_00897 7.12e-128 - - - - - - - -
HPEIFLPB_00898 0.00013 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HPEIFLPB_00899 3.15e-75 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HPEIFLPB_00900 9.53e-267 - - - S - - - Glycosyltransferase, group 2 family protein
HPEIFLPB_00901 0.0 - - - - - - - -
HPEIFLPB_00902 1.99e-36 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
HPEIFLPB_00903 1.93e-211 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HPEIFLPB_00904 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
HPEIFLPB_00905 0.0 - - - H - - - Protein of unknown function (DUF4012)
HPEIFLPB_00906 0.0 - - - V - - - ABC transporter permease
HPEIFLPB_00907 4.86e-271 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HPEIFLPB_00908 3.42e-178 - - - T ko:K06950 - ko00000 HD domain
HPEIFLPB_00909 3.34e-211 - - - S - - - Glutamine amidotransferase domain
HPEIFLPB_00910 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HPEIFLPB_00911 2.24e-236 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
HPEIFLPB_00912 2.13e-248 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
HPEIFLPB_00913 1.18e-51 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
HPEIFLPB_00915 5.25e-104 - - - K - - - Transcriptional regulator
HPEIFLPB_00916 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPEIFLPB_00917 1.14e-171 - - - - - - - -
HPEIFLPB_00918 1.6e-83 - - - - - - - -
HPEIFLPB_00919 1.32e-220 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPEIFLPB_00920 1.54e-162 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HPEIFLPB_00922 1.42e-172 - - - S - - - HAD hydrolase, family IA, variant 3
HPEIFLPB_00923 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat
HPEIFLPB_00924 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
HPEIFLPB_00925 9.12e-112 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
HPEIFLPB_00926 3.17e-235 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
HPEIFLPB_00927 3.29e-80 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPEIFLPB_00928 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HPEIFLPB_00929 0.0 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
HPEIFLPB_00930 1.12e-242 - - - K - - - Psort location Cytoplasmic, score
HPEIFLPB_00932 1.02e-171 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
HPEIFLPB_00933 9.49e-90 - - - S - - - Protein of unknown function (DUF4235)
HPEIFLPB_00934 1.89e-182 nfrA - - C - - - Nitroreductase family
HPEIFLPB_00935 2.45e-61 - - - - - - - -
HPEIFLPB_00936 8.49e-106 - - - S - - - SOS response associated peptidase (SRAP)
HPEIFLPB_00937 5.28e-31 - - - L - - - Transposase
HPEIFLPB_00938 4.88e-236 - - - S - - - Acetyltransferase (GNAT) domain
HPEIFLPB_00940 4.46e-46 - - - S - - - Carbon-nitrogen hydrolase
HPEIFLPB_00942 9.65e-50 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
HPEIFLPB_00943 1.9e-74 - - - K - - - Transcriptional regulator
HPEIFLPB_00944 1.12e-126 - - - K - - - FR47-like protein
HPEIFLPB_00945 3.32e-155 - - - J - - - Acetyltransferase (GNAT) domain
HPEIFLPB_00946 9.61e-84 - - - K - - - Protein of unknown function, DUF488
HPEIFLPB_00947 2e-205 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPEIFLPB_00948 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
HPEIFLPB_00949 1.85e-176 - - - S - - - Domain of unknown function (DUF4194)
HPEIFLPB_00950 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
HPEIFLPB_00951 0.0 - - - E - - - Serine carboxypeptidase
HPEIFLPB_00952 1.72e-208 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HPEIFLPB_00953 2.45e-218 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HPEIFLPB_00954 2.75e-216 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HPEIFLPB_00955 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HPEIFLPB_00956 1.08e-160 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
HPEIFLPB_00957 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
HPEIFLPB_00958 8.65e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HPEIFLPB_00959 3.13e-153 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
HPEIFLPB_00960 1.03e-202 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
HPEIFLPB_00961 4.23e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
HPEIFLPB_00962 2.66e-249 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPEIFLPB_00964 1.34e-167 - - - M - - - Peptidase family M23
HPEIFLPB_00965 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HPEIFLPB_00966 0.0 - - - G - - - ABC transporter substrate-binding protein
HPEIFLPB_00967 1.35e-306 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
HPEIFLPB_00968 1.59e-255 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
HPEIFLPB_00969 5.1e-118 - - - - - - - -
HPEIFLPB_00970 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
HPEIFLPB_00971 4.26e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPEIFLPB_00972 3.07e-188 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HPEIFLPB_00973 4.78e-188 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPEIFLPB_00974 1.1e-164 - - - S - - - alpha beta
HPEIFLPB_00975 6.31e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HPEIFLPB_00976 7.62e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPEIFLPB_00977 1.27e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
HPEIFLPB_00978 2.19e-291 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPEIFLPB_00979 1.82e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPEIFLPB_00980 6.57e-97 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPEIFLPB_00981 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPEIFLPB_00982 9.56e-317 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HPEIFLPB_00983 3.93e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_00984 1.93e-215 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
HPEIFLPB_00985 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
HPEIFLPB_00986 8.35e-229 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HPEIFLPB_00987 1.05e-276 - - - GK - - - ROK family
HPEIFLPB_00988 1.41e-263 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
HPEIFLPB_00989 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HPEIFLPB_00990 8.31e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HPEIFLPB_00991 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
HPEIFLPB_00992 1.39e-179 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HPEIFLPB_00993 0.0 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HPEIFLPB_00994 2.13e-151 - - - K - - - Transcriptional regulatory protein, C terminal
HPEIFLPB_00995 1.48e-36 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HPEIFLPB_00996 3.75e-116 - - - - - - - -
HPEIFLPB_00997 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPEIFLPB_00998 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPEIFLPB_00999 2.6e-231 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
HPEIFLPB_01000 7.42e-228 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HPEIFLPB_01001 3.23e-222 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HPEIFLPB_01002 6.71e-284 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
HPEIFLPB_01003 7.44e-187 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPEIFLPB_01004 1.2e-45 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
HPEIFLPB_01005 4.3e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HPEIFLPB_01006 2.85e-207 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPEIFLPB_01007 5.74e-303 - - - V - - - MatE
HPEIFLPB_01008 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HPEIFLPB_01009 3.12e-182 - - - S - - - Protein of unknown function (DUF1275)
HPEIFLPB_01010 4.49e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HPEIFLPB_01011 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
HPEIFLPB_01012 5.94e-282 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPEIFLPB_01013 6.31e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPEIFLPB_01014 1.36e-202 - - - G - - - Fructosamine kinase
HPEIFLPB_01015 2.74e-214 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPEIFLPB_01016 2.89e-199 - - - S - - - PAC2 family
HPEIFLPB_01020 0.0 - - - - - - - -
HPEIFLPB_01023 0.0 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPEIFLPB_01024 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPEIFLPB_01025 0.0 - 3.2.1.52 GH20 M ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
HPEIFLPB_01026 2.79e-176 yebC - - K - - - transcriptional regulatory protein
HPEIFLPB_01027 2.64e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HPEIFLPB_01028 1.83e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPEIFLPB_01029 6.91e-259 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPEIFLPB_01030 2.15e-71 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
HPEIFLPB_01031 3.9e-131 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPEIFLPB_01032 2.34e-284 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HPEIFLPB_01033 4.72e-212 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HPEIFLPB_01034 2.72e-314 - - - - - - - -
HPEIFLPB_01035 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HPEIFLPB_01036 5.17e-56 - - - - - - - -
HPEIFLPB_01037 9.88e-167 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HPEIFLPB_01038 9.44e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HPEIFLPB_01039 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HPEIFLPB_01040 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPEIFLPB_01041 1.31e-209 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPEIFLPB_01042 1.12e-246 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPEIFLPB_01043 8.92e-144 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
HPEIFLPB_01044 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
HPEIFLPB_01045 1.07e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
HPEIFLPB_01046 1.1e-151 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPEIFLPB_01047 8.87e-220 - - - S - - - Bacterial protein of unknown function (DUF881)
HPEIFLPB_01048 2.78e-57 sbp - - S - - - Protein of unknown function (DUF1290)
HPEIFLPB_01049 4.58e-181 - - - S - - - Bacterial protein of unknown function (DUF881)
HPEIFLPB_01050 2.88e-96 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
HPEIFLPB_01051 5.64e-153 merR2 - - K - - - helix_turn_helix, mercury resistance
HPEIFLPB_01052 8.13e-82 - - - - - - - -
HPEIFLPB_01054 1.04e-31 - - - L - - - DNA integration
HPEIFLPB_01055 4.36e-162 - - - S - - - GyrI-like small molecule binding domain
HPEIFLPB_01056 1.23e-116 - - - K - - - Putative zinc ribbon domain
HPEIFLPB_01059 5.93e-183 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
HPEIFLPB_01060 9.13e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HPEIFLPB_01061 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
HPEIFLPB_01062 1.24e-68 - - - - - - - -
HPEIFLPB_01063 0.0 - - - K - - - WYL domain
HPEIFLPB_01064 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HPEIFLPB_01066 5.71e-78 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
HPEIFLPB_01067 1.45e-183 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HPEIFLPB_01068 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPEIFLPB_01069 6.72e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HPEIFLPB_01070 1.23e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HPEIFLPB_01071 9.61e-121 - - - T - - - Domain of unknown function (DUF4234)
HPEIFLPB_01072 1.66e-131 - - - K - - - Bacterial regulatory proteins, tetR family
HPEIFLPB_01073 3.56e-24 - - - - - - - -
HPEIFLPB_01074 1.02e-64 tam 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
HPEIFLPB_01075 1.17e-54 - - - K - - - Helix-turn-helix
HPEIFLPB_01076 1.99e-284 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
HPEIFLPB_01077 1.74e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
HPEIFLPB_01078 1.13e-226 - - - S ko:K07088 - ko00000 Membrane transport protein
HPEIFLPB_01079 1.51e-121 - - - K - - - Transcriptional regulator PadR-like family
HPEIFLPB_01080 8.37e-171 - - - L ko:K07457 - ko00000 endonuclease III
HPEIFLPB_01081 6.88e-169 - - - S - - - Enoyl-(Acyl carrier protein) reductase
HPEIFLPB_01082 4.85e-312 - - - V - - - MatE
HPEIFLPB_01083 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HPEIFLPB_01084 1.36e-19 - - - KLT - - - Protein tyrosine kinase
HPEIFLPB_01086 4.99e-219 - - - - - - - -
HPEIFLPB_01087 8.91e-248 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HPEIFLPB_01088 2.41e-23 - - - K - - - MerR family regulatory protein
HPEIFLPB_01089 5.01e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPEIFLPB_01090 7.1e-230 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPEIFLPB_01091 2.94e-199 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HPEIFLPB_01092 2.81e-231 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
HPEIFLPB_01093 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPEIFLPB_01094 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HPEIFLPB_01095 6.38e-233 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HPEIFLPB_01096 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HPEIFLPB_01098 7.86e-207 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
HPEIFLPB_01099 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPEIFLPB_01103 2.27e-170 - - - M - - - NLP P60 protein
HPEIFLPB_01104 2.3e-83 - - - S - - - SPP1 phage holin
HPEIFLPB_01106 1.21e-90 - - - - - - - -
HPEIFLPB_01107 1.56e-191 - - - - - - - -
HPEIFLPB_01108 1.66e-87 - - - - - - - -
HPEIFLPB_01109 0.0 - - - S - - - Prophage endopeptidase tail
HPEIFLPB_01110 4.33e-188 - - - S - - - phage tail
HPEIFLPB_01111 0.0 - - - S - - - Phage-related minor tail protein
HPEIFLPB_01112 1.77e-70 - - - - - - - -
HPEIFLPB_01113 4.54e-108 - - - - - - - -
HPEIFLPB_01114 3.53e-123 - - - - - - - -
HPEIFLPB_01115 1.65e-93 - - - - - - - -
HPEIFLPB_01116 6.59e-96 - - - - - - - -
HPEIFLPB_01117 3.65e-103 - - - - - - - -
HPEIFLPB_01118 2.99e-119 - - - - - - - -
HPEIFLPB_01119 6.75e-81 - - - - - - - -
HPEIFLPB_01120 1.66e-223 - - - S - - - Phage capsid family
HPEIFLPB_01121 1.43e-124 - - - - - - - -
HPEIFLPB_01122 2.73e-58 - - - - - - - -
HPEIFLPB_01123 3.87e-305 - - - - - - - -
HPEIFLPB_01124 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HPEIFLPB_01125 0.0 - - - S - - - Terminase
HPEIFLPB_01126 1.89e-91 - - - - - - - -
HPEIFLPB_01127 1.6e-104 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPEIFLPB_01128 7.99e-226 - - - M - - - heme binding
HPEIFLPB_01129 3.96e-97 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HPEIFLPB_01131 1.46e-202 - - - - - - - -
HPEIFLPB_01132 3.96e-115 - - - S - - - Putative ABC-transporter type IV
HPEIFLPB_01133 5.99e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HPEIFLPB_01134 9.24e-246 - - - V - - - VanZ like family
HPEIFLPB_01135 7.78e-56 - - - KT - - - RESPONSE REGULATOR receiver
HPEIFLPB_01136 1.84e-68 - - - KT - - - RESPONSE REGULATOR receiver
HPEIFLPB_01137 3.34e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
HPEIFLPB_01138 1.03e-186 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
HPEIFLPB_01139 2.71e-168 - - - C - - - Putative TM nitroreductase
HPEIFLPB_01140 2.54e-63 - - - - - - - -
HPEIFLPB_01142 0.0 treS_1 - - G - - - Alpha amylase, catalytic domain
HPEIFLPB_01143 1.08e-101 - - - S - - - Bacterial PH domain
HPEIFLPB_01144 5.51e-176 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HPEIFLPB_01145 6.1e-89 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPEIFLPB_01146 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPEIFLPB_01148 6.24e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPEIFLPB_01149 5.93e-187 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPEIFLPB_01150 2.56e-120 - - - - - - - -
HPEIFLPB_01151 3.42e-298 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPEIFLPB_01152 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
HPEIFLPB_01153 3.24e-158 - - - S - - - ABC-2 family transporter protein
HPEIFLPB_01154 1.02e-161 - - - S - - - ABC-2 family transporter protein
HPEIFLPB_01155 9e-227 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_01156 6.98e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HPEIFLPB_01157 3.05e-159 - - - S - - - Haloacid dehalogenase-like hydrolase
HPEIFLPB_01158 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HPEIFLPB_01159 3.15e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPEIFLPB_01160 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
HPEIFLPB_01161 8.69e-149 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
HPEIFLPB_01162 1.07e-141 - - - - - - - -
HPEIFLPB_01163 1.33e-174 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HPEIFLPB_01165 2.08e-240 - - - G - - - Haloacid dehalogenase-like hydrolase
HPEIFLPB_01166 8.71e-277 - - - L - - - Tetratricopeptide repeat
HPEIFLPB_01167 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPEIFLPB_01168 1.02e-184 - - - S - - - Putative ABC-transporter type IV
HPEIFLPB_01169 2.65e-139 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HPEIFLPB_01170 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HPEIFLPB_01171 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HPEIFLPB_01172 0.0 - - - K - - - Putative DNA-binding domain
HPEIFLPB_01173 7.46e-72 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
HPEIFLPB_01174 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
HPEIFLPB_01175 4.47e-199 - - - S - - - Domain of unknown function (DUF4357)
HPEIFLPB_01176 2e-41 - - - - - - - -
HPEIFLPB_01177 8.68e-229 - - - L - - - Phage integrase family
HPEIFLPB_01178 5.96e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPEIFLPB_01179 1.29e-112 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HPEIFLPB_01180 2.51e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPEIFLPB_01181 9.75e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HPEIFLPB_01182 4.12e-227 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HPEIFLPB_01183 1.74e-273 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPEIFLPB_01184 4.51e-261 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPEIFLPB_01185 7.11e-133 - - - - - - - -
HPEIFLPB_01186 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
HPEIFLPB_01187 1.51e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPEIFLPB_01188 3.72e-204 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPEIFLPB_01189 8.29e-174 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_01190 2.65e-175 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HPEIFLPB_01191 7.28e-71 - - - IQ - - - oxidoreductase activity
HPEIFLPB_01193 5.16e-103 - - - K - - - AraC-like ligand binding domain
HPEIFLPB_01194 2.75e-304 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
HPEIFLPB_01195 9.93e-204 - - - G - - - Phosphoglycerate mutase family
HPEIFLPB_01196 1.58e-64 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
HPEIFLPB_01197 6.42e-240 - - - S - - - Conserved hypothetical protein 698
HPEIFLPB_01198 3.01e-185 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HPEIFLPB_01199 3.25e-137 - - - E - - - haloacid dehalogenase-like hydrolase
HPEIFLPB_01200 0.0 - - - M - - - Glycosyltransferase like family 2
HPEIFLPB_01202 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
HPEIFLPB_01203 3.7e-161 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
HPEIFLPB_01204 1.5e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPEIFLPB_01205 2.8e-67 - - - - - - - -
HPEIFLPB_01206 1.66e-46 - - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HPEIFLPB_01207 7.03e-86 - - - S - - - Zincin-like metallopeptidase
HPEIFLPB_01208 1.1e-112 - - - S - - - Helix-turn-helix
HPEIFLPB_01209 7.74e-264 - - - S - - - Short C-terminal domain
HPEIFLPB_01210 1.1e-30 - - - - - - - -
HPEIFLPB_01212 6.04e-103 - - - K - - - Psort location Cytoplasmic, score
HPEIFLPB_01213 0.0 - - - KLT - - - Protein tyrosine kinase
HPEIFLPB_01214 6.01e-101 - - - S - - - Cupin 2, conserved barrel domain protein
HPEIFLPB_01215 3.83e-202 - - - J - - - Methyltransferase domain
HPEIFLPB_01216 5.59e-78 yccF - - S - - - Inner membrane component domain
HPEIFLPB_01217 1.58e-161 - - - E - - - Psort location Cytoplasmic, score 8.87
HPEIFLPB_01218 2.3e-312 - - - K - - - Fic/DOC family
HPEIFLPB_01219 7.17e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPEIFLPB_01220 1.48e-291 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HPEIFLPB_01221 9.77e-123 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_01222 8.13e-263 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPEIFLPB_01223 1.63e-237 acoB 1.2.4.1, 1.2.4.4 - C ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
HPEIFLPB_01224 2.43e-240 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HPEIFLPB_01225 9.38e-190 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
HPEIFLPB_01226 2.08e-213 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
HPEIFLPB_01227 2.89e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPEIFLPB_01228 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
HPEIFLPB_01229 0.0 - - - T - - - Histidine kinase
HPEIFLPB_01230 2.4e-170 - - - K - - - helix_turn_helix, Lux Regulon
HPEIFLPB_01231 0.0 - - - I - - - PAP2 superfamily
HPEIFLPB_01232 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HPEIFLPB_01233 2.96e-210 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPEIFLPB_01234 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
HPEIFLPB_01235 9.86e-202 - - - S - - - Putative ABC-transporter type IV
HPEIFLPB_01236 3.62e-212 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HPEIFLPB_01237 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
HPEIFLPB_01238 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
HPEIFLPB_01239 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
HPEIFLPB_01240 2.23e-93 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
HPEIFLPB_01241 1.24e-235 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HPEIFLPB_01242 1.75e-151 safC - - S - - - O-methyltransferase
HPEIFLPB_01243 4.26e-222 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HPEIFLPB_01244 9.66e-290 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HPEIFLPB_01245 3.66e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
HPEIFLPB_01248 1.23e-311 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPEIFLPB_01249 9.32e-164 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPEIFLPB_01250 4.05e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPEIFLPB_01252 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
HPEIFLPB_01253 9.36e-310 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPEIFLPB_01254 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
HPEIFLPB_01255 1.94e-146 - - - S - - - Protein of unknown function (DUF3000)
HPEIFLPB_01256 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPEIFLPB_01257 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HPEIFLPB_01258 5.26e-63 - - - - - - - -
HPEIFLPB_01259 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPEIFLPB_01260 6.67e-284 - - - S - - - Peptidase dimerisation domain
HPEIFLPB_01261 1.51e-111 - - - P - - - ABC-type metal ion transport system permease component
HPEIFLPB_01262 6.76e-213 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPEIFLPB_01263 2.6e-222 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPEIFLPB_01264 4.36e-46 - - - - - - - -
HPEIFLPB_01265 2.85e-65 - - - - - - - -
HPEIFLPB_01267 9.83e-155 - - - - - - - -
HPEIFLPB_01268 3.88e-38 - - - - - - - -
HPEIFLPB_01269 2.12e-257 - - - S - - - Helix-turn-helix domain
HPEIFLPB_01270 1.91e-57 - - - - - - - -
HPEIFLPB_01271 8.56e-119 - - - S - - - Transcription factor WhiB
HPEIFLPB_01272 2.09e-150 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
HPEIFLPB_01273 3.59e-240 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPEIFLPB_01274 3.69e-198 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_01275 1.38e-183 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
HPEIFLPB_01276 9.72e-205 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_01277 1.72e-218 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPEIFLPB_01278 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HPEIFLPB_01279 2.65e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HPEIFLPB_01280 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HPEIFLPB_01281 4.05e-93 - - - G ko:K02027 - ko00000,ko00002,ko02000 carbohydrate transport
HPEIFLPB_01282 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HPEIFLPB_01283 4.92e-159 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
HPEIFLPB_01284 2.17e-243 - - - K - - - Periplasmic binding protein domain
HPEIFLPB_01285 2.47e-26 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HPEIFLPB_01286 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
HPEIFLPB_01287 7.3e-24 - - - L - - - Helix-turn-helix domain
HPEIFLPB_01288 1.47e-11 - - - S - - - Protein of unknown function (DUF2442)
HPEIFLPB_01289 8.59e-23 - - - K - - - Helix-turn-helix domain
HPEIFLPB_01290 1.71e-133 - - - L - - - Belongs to the 'phage' integrase family
HPEIFLPB_01291 1.34e-93 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 COG0732 Restriction endonuclease S subunits
HPEIFLPB_01292 9.05e-306 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
HPEIFLPB_01293 0.0 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HPEIFLPB_01294 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPEIFLPB_01295 4.8e-73 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HPEIFLPB_01296 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
HPEIFLPB_01297 3.06e-179 hflK - - O - - - prohibitin homologues
HPEIFLPB_01298 7.38e-310 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
HPEIFLPB_01299 1.82e-297 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HPEIFLPB_01300 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
HPEIFLPB_01301 4.16e-280 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HPEIFLPB_01302 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_01303 0.0 - - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HPEIFLPB_01304 2.11e-119 - - - K - - - acetyltransferase
HPEIFLPB_01305 2.16e-103 - - - EGP - - - Major Facilitator Superfamily
HPEIFLPB_01306 1.04e-249 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
HPEIFLPB_01307 2.92e-131 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
HPEIFLPB_01308 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
HPEIFLPB_01309 6.17e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HPEIFLPB_01310 2.65e-194 - - - S - - - Short repeat of unknown function (DUF308)
HPEIFLPB_01311 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
HPEIFLPB_01312 6.9e-157 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
HPEIFLPB_01313 5.42e-219 - - - - - - - -
HPEIFLPB_01314 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPEIFLPB_01315 2.54e-230 - - - I - - - PAP2 superfamily
HPEIFLPB_01316 2.83e-47 - - - NU - - - Tfp pilus assembly protein FimV
HPEIFLPB_01317 0.0 - - - L - - - PIF1-like helicase
HPEIFLPB_01318 7.5e-201 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPEIFLPB_01319 7.49e-154 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HPEIFLPB_01320 1.03e-26 - - - KT ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HPEIFLPB_01321 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
HPEIFLPB_01322 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HPEIFLPB_01323 1.06e-260 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
HPEIFLPB_01324 7.44e-151 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
HPEIFLPB_01325 8.39e-73 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
HPEIFLPB_01326 1.7e-236 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPEIFLPB_01327 1.17e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPEIFLPB_01328 1.85e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HPEIFLPB_01330 1.96e-251 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
HPEIFLPB_01331 6.45e-208 - - - G ko:K05340 - ko00000,ko02000 Sugar transport protein
HPEIFLPB_01332 3.32e-240 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HPEIFLPB_01333 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
HPEIFLPB_01334 3.52e-142 - - - - - - - -
HPEIFLPB_01335 2.28e-218 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
HPEIFLPB_01336 9.71e-190 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HPEIFLPB_01337 0.0 - - - JKL - - - helicase superfamily c-terminal domain
HPEIFLPB_01338 1.23e-210 - - - EG - - - EamA-like transporter family
HPEIFLPB_01340 3.7e-189 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HPEIFLPB_01341 2.03e-191 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
HPEIFLPB_01342 5.38e-273 - - - S - - - Psort location Cytoplasmic, score 8.87
HPEIFLPB_01343 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
HPEIFLPB_01344 7.9e-48 - - - C - - - Aldo/keto reductase family
HPEIFLPB_01345 1.54e-100 - - - EGP - - - Major facilitator superfamily
HPEIFLPB_01346 3.68e-229 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HPEIFLPB_01347 0.0 - - - S - - - ATPases associated with a variety of cellular activities
HPEIFLPB_01348 6.7e-74 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
HPEIFLPB_01349 2.95e-201 - - - I - - - alpha/beta hydrolase fold
HPEIFLPB_01350 4.04e-149 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
HPEIFLPB_01352 5.13e-65 - - - S - - - DUF218 domain
HPEIFLPB_01353 4.3e-42 - - - S - - - DUF218 domain
HPEIFLPB_01354 1.27e-22 - - - S - - - Protein of unknown function (DUF979)
HPEIFLPB_01355 1.24e-147 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPEIFLPB_01357 1.76e-161 - - - - - - - -
HPEIFLPB_01358 1.9e-73 - - - M - - - domain, Protein
HPEIFLPB_01359 8.64e-24 - - - M - - - domain, Protein
HPEIFLPB_01360 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
HPEIFLPB_01361 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
HPEIFLPB_01362 2.66e-219 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
HPEIFLPB_01363 2.35e-107 - - - S - - - Protein of unknown function (DUF3180)
HPEIFLPB_01364 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPEIFLPB_01365 3.91e-211 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPEIFLPB_01366 2.05e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HPEIFLPB_01367 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPEIFLPB_01368 2.65e-127 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HPEIFLPB_01369 2.1e-270 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPEIFLPB_01370 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
HPEIFLPB_01371 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HPEIFLPB_01372 1.86e-214 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_01373 3.97e-295 - - - M - - - Glycosyl transferase family 21
HPEIFLPB_01374 0.0 - - - S - - - AI-2E family transporter
HPEIFLPB_01375 1.89e-227 - - - M - - - Glycosyltransferase like family 2
HPEIFLPB_01376 1.48e-271 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
HPEIFLPB_01379 2.87e-110 - - - S - - - Domain of unknown function (DUF4190)
HPEIFLPB_01380 6.57e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HPEIFLPB_01381 2.9e-224 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPEIFLPB_01383 3.11e-23 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
HPEIFLPB_01384 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HPEIFLPB_01385 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HPEIFLPB_01386 3.34e-117 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
HPEIFLPB_01387 2.71e-235 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HPEIFLPB_01388 1.71e-302 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HPEIFLPB_01389 5.05e-153 - - - K - - - Transcriptional regulatory protein, C terminal
HPEIFLPB_01390 1.64e-138 - - - - - - - -
HPEIFLPB_01391 1.38e-66 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
HPEIFLPB_01392 1.85e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
HPEIFLPB_01394 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
HPEIFLPB_01395 0.0 - - - S - - - Putative esterase
HPEIFLPB_01396 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
HPEIFLPB_01397 3.09e-306 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HPEIFLPB_01398 2.1e-245 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HPEIFLPB_01399 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPEIFLPB_01400 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
HPEIFLPB_01401 8.09e-44 - - - - - - - -
HPEIFLPB_01402 1.64e-90 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPEIFLPB_01403 2.12e-31 - - - K - - - DNA-binding transcription factor activity
HPEIFLPB_01404 8.99e-179 nnrE - - L - - - Uracil DNA glycosylase superfamily
HPEIFLPB_01405 2.2e-140 - - - S - - - Protein of unknown function (DUF4230)
HPEIFLPB_01406 1.08e-146 - - - - - - - -
HPEIFLPB_01407 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
HPEIFLPB_01408 2.05e-177 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HPEIFLPB_01409 1.83e-296 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPEIFLPB_01410 0.0 - - - M - - - Parallel beta-helix repeats
HPEIFLPB_01411 1.04e-289 - - - M - - - Glycosyl transferase 4-like domain
HPEIFLPB_01412 5.42e-255 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
HPEIFLPB_01414 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPEIFLPB_01415 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPEIFLPB_01416 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPEIFLPB_01417 5.83e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPEIFLPB_01418 0.0 - - - S - - - Esterase-like activity of phytase
HPEIFLPB_01419 1.52e-252 - - - EGP - - - Transmembrane secretion effector
HPEIFLPB_01421 3.8e-135 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPEIFLPB_01422 1.61e-147 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPEIFLPB_01423 1.4e-303 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HPEIFLPB_01424 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HPEIFLPB_01425 0.0 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HPEIFLPB_01426 0.0 - - - S - - - Protein of unknown function DUF262
HPEIFLPB_01427 1.75e-151 - - - K - - - helix_turn_helix, Lux Regulon
HPEIFLPB_01428 0.0 - - - T - - - Histidine kinase
HPEIFLPB_01429 2.17e-151 - - - S - - - Domain of unknown function (DUF5067)
HPEIFLPB_01430 8.71e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
HPEIFLPB_01431 1.01e-214 - - - EG - - - EamA-like transporter family
HPEIFLPB_01432 1.42e-156 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
HPEIFLPB_01433 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPEIFLPB_01434 4.21e-234 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPEIFLPB_01435 1.89e-176 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HPEIFLPB_01436 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
HPEIFLPB_01437 9.72e-157 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPEIFLPB_01438 1.14e-124 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HPEIFLPB_01439 1.03e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
HPEIFLPB_01440 3.38e-54 - - - S - - - Protein of unknown function (DUF3046)
HPEIFLPB_01441 7.71e-276 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPEIFLPB_01442 1.2e-113 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HPEIFLPB_01445 3.68e-152 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPEIFLPB_01446 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPEIFLPB_01447 3.6e-243 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPEIFLPB_01448 4.56e-142 - - - - - - - -
HPEIFLPB_01449 2.06e-171 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HPEIFLPB_01450 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
HPEIFLPB_01451 3.16e-257 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HPEIFLPB_01452 3.42e-158 - - - - - - - -
HPEIFLPB_01453 3.82e-260 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPEIFLPB_01454 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
HPEIFLPB_01455 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HPEIFLPB_01456 5.76e-60 - - - S - - - Protein of unknown function (DUF2975)
HPEIFLPB_01457 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
HPEIFLPB_01458 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
HPEIFLPB_01459 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
HPEIFLPB_01460 1.1e-298 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
HPEIFLPB_01461 3.19e-239 - - - S - - - Protein of unknown function (DUF3071)
HPEIFLPB_01462 2.45e-63 - - - S - - - Domain of unknown function (DUF4193)
HPEIFLPB_01463 1.42e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HPEIFLPB_01464 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPEIFLPB_01465 2.33e-39 - - - - - - - -
HPEIFLPB_01467 2.96e-265 - - - E - - - Belongs to the peptidase S1B family
HPEIFLPB_01468 1.78e-89 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
HPEIFLPB_01469 2.34e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HPEIFLPB_01470 0.0 intA - - L - - - Phage integrase family
HPEIFLPB_01471 2.24e-75 - - - - - - - -
HPEIFLPB_01472 6.4e-123 - - - L - - - Restriction endonuclease NotI
HPEIFLPB_01474 1.55e-62 - - - - - - - -
HPEIFLPB_01475 8.66e-57 - - - O - - - Glutaredoxin
HPEIFLPB_01476 5.48e-199 - - - S ko:K07058 - ko00000 Virulence factor BrkB
HPEIFLPB_01477 8.29e-129 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
HPEIFLPB_01478 9.3e-53 urtE - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPEIFLPB_01479 5.48e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPEIFLPB_01480 2.21e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPEIFLPB_01481 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HPEIFLPB_01482 4.31e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HPEIFLPB_01483 2.46e-132 - - - K - - - Transcriptional regulator C-terminal region
HPEIFLPB_01484 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
HPEIFLPB_01485 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HPEIFLPB_01486 1.15e-234 - - - S - - - Protein of unknown function (DUF559)
HPEIFLPB_01487 7.18e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPEIFLPB_01488 6.15e-261 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPEIFLPB_01489 0.0 - - - EGP - - - Sugar (and other) transporter
HPEIFLPB_01490 0.0 scrT - - G - - - Transporter major facilitator family protein
HPEIFLPB_01491 1.89e-100 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
HPEIFLPB_01492 2.71e-255 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPEIFLPB_01493 3.43e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPEIFLPB_01494 2.51e-210 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPEIFLPB_01495 1.94e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPEIFLPB_01496 2.17e-253 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HPEIFLPB_01497 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HPEIFLPB_01498 1.42e-74 - - - K - - - Cro/C1-type HTH DNA-binding domain
HPEIFLPB_01500 7.82e-65 - - - E - - - IrrE N-terminal-like domain
HPEIFLPB_01501 4.81e-84 - - - - - - - -
HPEIFLPB_01502 4.37e-80 - - - - - - - -
HPEIFLPB_01504 3.76e-163 - - - S - - - Domain of unknown function (DUF4417)
HPEIFLPB_01505 7.44e-57 - - - S - - - Bacterial mobilisation protein (MobC)
HPEIFLPB_01506 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HPEIFLPB_01508 1.18e-223 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HPEIFLPB_01509 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
HPEIFLPB_01510 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HPEIFLPB_01511 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
HPEIFLPB_01512 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPEIFLPB_01514 2.83e-113 - - - Q - - - Acetyltransferase (GNAT) domain
HPEIFLPB_01515 3.19e-201 - - - I - - - Serine aminopeptidase, S33
HPEIFLPB_01516 3.02e-70 - - - S - - - Putative heavy-metal-binding
HPEIFLPB_01517 2.75e-61 - - - - - - - -
HPEIFLPB_01518 9.44e-116 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HPEIFLPB_01519 0.0 - - - KL - - - Domain of unknown function (DUF3427)
HPEIFLPB_01521 1.17e-250 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPEIFLPB_01523 5.5e-146 - - - - - - - -
HPEIFLPB_01524 2.66e-215 - - - EG - - - EamA-like transporter family
HPEIFLPB_01525 1.99e-262 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
HPEIFLPB_01526 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
HPEIFLPB_01527 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
HPEIFLPB_01528 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
HPEIFLPB_01529 3.69e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
HPEIFLPB_01530 1.44e-122 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
HPEIFLPB_01531 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
HPEIFLPB_01532 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HPEIFLPB_01533 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HPEIFLPB_01534 5.69e-234 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HPEIFLPB_01535 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HPEIFLPB_01536 9.5e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
HPEIFLPB_01537 9.77e-297 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HPEIFLPB_01538 2.05e-183 - - - S - - - Bacterial protein of unknown function (DUF881)
HPEIFLPB_01539 4.34e-94 crgA - - D - - - Involved in cell division
HPEIFLPB_01540 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
HPEIFLPB_01541 2.4e-186 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
HPEIFLPB_01542 7.68e-47 - - - - - - - -
HPEIFLPB_01544 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPEIFLPB_01545 5.53e-96 - - - I - - - Sterol carrier protein
HPEIFLPB_01546 1.63e-44 - - - V ko:K06147 - ko00000,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_01547 3.5e-57 - - - L ko:K07485 - ko00000 Transposase
HPEIFLPB_01548 1.35e-59 istB - - L - - - IstB-like ATP binding protein
HPEIFLPB_01549 7.04e-57 - - - L - - - Integrase core domain
HPEIFLPB_01550 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
HPEIFLPB_01551 1.9e-17 - - - - - - - -
HPEIFLPB_01552 5.05e-23 yccF - - S - - - Inner membrane component domain
HPEIFLPB_01553 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HPEIFLPB_01554 1.28e-84 - - - L ko:K07485 - ko00000 Transposase
HPEIFLPB_01555 3.29e-86 - - - S - - - Short C-terminal domain
HPEIFLPB_01556 2.16e-50 - - - L - - - Helix-turn-helix domain
HPEIFLPB_01557 1.3e-238 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPEIFLPB_01558 1.33e-64 - - - S ko:K07126 - ko00000 Sel1-like repeats.
HPEIFLPB_01559 1.18e-207 - - - S ko:K11206 - ko00000,ko01000 Carbon-nitrogen hydrolase
HPEIFLPB_01560 1.99e-232 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HPEIFLPB_01561 2.88e-313 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
HPEIFLPB_01562 5.23e-107 - - - - - - - -
HPEIFLPB_01563 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HPEIFLPB_01564 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
HPEIFLPB_01565 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
HPEIFLPB_01566 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
HPEIFLPB_01567 4.95e-18 - - - S ko:K07149 - ko00000 Membrane
HPEIFLPB_01568 8.1e-313 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HPEIFLPB_01569 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPEIFLPB_01570 3.91e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HPEIFLPB_01571 1.61e-175 - - - S - - - UPF0126 domain
HPEIFLPB_01572 3.93e-125 - - - T - - - RNA ligase
HPEIFLPB_01573 1.65e-61 - - - S - - - phosphoesterase or phosphohydrolase
HPEIFLPB_01574 1.58e-287 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
HPEIFLPB_01575 1.66e-128 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HPEIFLPB_01576 2.09e-242 - - - S ko:K06889 - ko00000 alpha beta
HPEIFLPB_01577 1.72e-306 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HPEIFLPB_01578 1.08e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
HPEIFLPB_01579 6.9e-259 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
HPEIFLPB_01580 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HPEIFLPB_01581 1.96e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPEIFLPB_01582 0.0 corC - - S - - - CBS domain
HPEIFLPB_01583 2.43e-130 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPEIFLPB_01584 1.05e-253 phoH - - T ko:K06217 - ko00000 PhoH-like protein
HPEIFLPB_01585 1.37e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HPEIFLPB_01586 2.18e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPEIFLPB_01588 1.78e-208 spoU2 - - J - - - SpoU rRNA Methylase family
HPEIFLPB_01589 1.42e-308 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPEIFLPB_01590 2.56e-141 - - - S - - - Iron-sulfur cluster assembly protein
HPEIFLPB_01591 4.14e-132 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HPEIFLPB_01592 3.1e-307 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPEIFLPB_01593 2.13e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HPEIFLPB_01594 8.37e-298 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
HPEIFLPB_01595 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
HPEIFLPB_01596 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPEIFLPB_01597 1.76e-05 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
HPEIFLPB_01598 3.46e-154 - - - K - - - helix_turn_helix, Lux Regulon
HPEIFLPB_01599 2.14e-21 - - - - - - - -
HPEIFLPB_01600 1.87e-102 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HPEIFLPB_01601 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPEIFLPB_01602 1.57e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPEIFLPB_01603 5.3e-69 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
HPEIFLPB_01604 4.48e-247 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPEIFLPB_01605 6.58e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPEIFLPB_01606 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPEIFLPB_01607 7.33e-50 - - - - - - - -
HPEIFLPB_01608 4.03e-85 - - - S - - - Bacterial protein of unknown function (DUF948)
HPEIFLPB_01609 4.37e-173 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
HPEIFLPB_01610 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
HPEIFLPB_01611 1.83e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPEIFLPB_01612 6.67e-173 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HPEIFLPB_01613 1.87e-271 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HPEIFLPB_01614 2.46e-84 - - - S - - - Domain of unknown function (DUF4418)
HPEIFLPB_01615 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HPEIFLPB_01616 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
HPEIFLPB_01617 6.52e-139 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPEIFLPB_01618 7.11e-309 pbuX - - F ko:K03458 - ko00000 Permease family
HPEIFLPB_01620 1.8e-47 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPEIFLPB_01622 5.11e-146 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
HPEIFLPB_01623 1.13e-53 - - - - - - - -
HPEIFLPB_01624 5.58e-33 - - - S - - - Adenine-specific methyltransferase EcoRI
HPEIFLPB_01625 1.63e-183 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
HPEIFLPB_01626 5.39e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HPEIFLPB_01627 1.12e-109 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPEIFLPB_01628 9.52e-132 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
HPEIFLPB_01629 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
HPEIFLPB_01630 1.73e-143 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
HPEIFLPB_01631 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
HPEIFLPB_01632 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HPEIFLPB_01634 2.55e-222 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPEIFLPB_01635 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
HPEIFLPB_01636 3.69e-198 - - - - - - - -
HPEIFLPB_01637 1.82e-230 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HPEIFLPB_01638 1.64e-312 - - - M - - - LPXTG-motif cell wall anchor domain protein
HPEIFLPB_01639 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
HPEIFLPB_01640 2.69e-133 - - - L - - - Helix-turn-helix domain
HPEIFLPB_01641 2.18e-269 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HPEIFLPB_01642 7.97e-223 - - - K - - - Psort location Cytoplasmic, score
HPEIFLPB_01643 0.0 - - - KLT - - - Protein tyrosine kinase
HPEIFLPB_01644 1.05e-200 - - - O - - - Thioredoxin
HPEIFLPB_01646 4.84e-280 rpfB - - S ko:K21688 - ko00000 G5
HPEIFLPB_01647 6.28e-218 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPEIFLPB_01648 3.96e-215 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPEIFLPB_01649 1.99e-145 - - - S - - - LytR cell envelope-related transcriptional attenuator
HPEIFLPB_01650 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
HPEIFLPB_01651 3.18e-160 mutT4 - - L - - - Belongs to the Nudix hydrolase family
HPEIFLPB_01652 0.0 - - - M - - - Conserved repeat domain
HPEIFLPB_01653 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
HPEIFLPB_01654 7.93e-258 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPEIFLPB_01655 4.26e-307 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HPEIFLPB_01656 1.05e-229 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HPEIFLPB_01657 6.09e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HPEIFLPB_01658 4.85e-119 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
HPEIFLPB_01659 6.04e-227 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
HPEIFLPB_01660 3.88e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HPEIFLPB_01661 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPEIFLPB_01662 1.15e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPEIFLPB_01663 4.66e-296 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPEIFLPB_01664 1.36e-125 - - - S - - - Protein of unknown function (DUF721)
HPEIFLPB_01665 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPEIFLPB_01666 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPEIFLPB_01667 4.11e-104 - - - S - - - Transmembrane domain of unknown function (DUF3566)
HPEIFLPB_01669 1.24e-239 - - - G - - - Glycosyl hydrolases family 43
HPEIFLPB_01670 2.97e-236 - - - K - - - Periplasmic binding protein domain
HPEIFLPB_01671 7.56e-290 - - - I - - - Serine aminopeptidase, S33
HPEIFLPB_01672 1.56e-11 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPEIFLPB_01673 2.87e-56 - - - S - - - Protein of unknown function (DUF2442)
HPEIFLPB_01674 4.93e-141 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HPEIFLPB_01675 0.0 - 2.1.1.72 - L ko:K07317 - ko00000,ko01000,ko02048 Eco57I restriction-modification methylase
HPEIFLPB_01676 1.05e-216 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 BsuBI/PstI restriction endonuclease C-terminus
HPEIFLPB_01677 1.49e-290 - - - - - - - -
HPEIFLPB_01679 2.82e-236 - - - L - - - Phage integrase family
HPEIFLPB_01680 1.52e-07 - - - M - - - PA domain
HPEIFLPB_01681 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HPEIFLPB_01682 3.5e-162 gntR - - K - - - FCD
HPEIFLPB_01683 9.15e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPEIFLPB_01684 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
HPEIFLPB_01687 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
HPEIFLPB_01688 7.28e-244 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPEIFLPB_01689 5.12e-101 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPEIFLPB_01690 1.49e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HPEIFLPB_01691 0.0 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HPEIFLPB_01692 5.11e-176 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
HPEIFLPB_01693 2.68e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HPEIFLPB_01694 4.89e-241 - - - EG - - - EamA-like transporter family
HPEIFLPB_01695 1.37e-305 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
HPEIFLPB_01696 1.73e-95 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPEIFLPB_01697 6.08e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HPEIFLPB_01698 1.01e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
HPEIFLPB_01699 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HPEIFLPB_01700 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HPEIFLPB_01701 1.95e-308 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HPEIFLPB_01702 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HPEIFLPB_01703 0.0 - - - S - - - Threonine/Serine exporter, ThrE
HPEIFLPB_01704 1.47e-225 - - - S - - - Amidohydrolase family
HPEIFLPB_01705 4.09e-249 - - - S - - - Protein conserved in bacteria
HPEIFLPB_01706 9.85e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HPEIFLPB_01707 5.42e-67 - - - S - - - Protein of unknown function (DUF3073)
HPEIFLPB_01708 3.18e-112 - - - K - - - LytTr DNA-binding domain
HPEIFLPB_01709 1.64e-136 - - - T - - - protein histidine kinase activity
HPEIFLPB_01710 1.24e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPEIFLPB_01711 5.03e-34 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HPEIFLPB_01712 0.0 - - - M - - - Glycosyl hydrolases family 25
HPEIFLPB_01713 2.97e-216 - - - M - - - Glycosyl transferase family 2
HPEIFLPB_01714 0.0 - - - - - - - -
HPEIFLPB_01715 7.73e-259 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPEIFLPB_01716 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
HPEIFLPB_01717 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPEIFLPB_01718 2.39e-59 - - - L - - - Transposase DDE domain
HPEIFLPB_01719 5.51e-164 - - - - - - - -
HPEIFLPB_01720 0.0 res 3.1.21.5 - V ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
HPEIFLPB_01721 7.72e-300 mod 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
HPEIFLPB_01722 4.59e-159 - - - S - - - Domain of unknown function (DUF4391)
HPEIFLPB_01723 0.0 - - - L - - - helicase
HPEIFLPB_01724 6.78e-135 - - - - - - - -
HPEIFLPB_01725 0.0 - - - S - - - Protein of unknown function DUF262
HPEIFLPB_01726 5.4e-39 - - - - - - - -
HPEIFLPB_01727 4.94e-125 - - - E - - - Rard protein
HPEIFLPB_01728 1.62e-227 - - - I - - - alpha/beta hydrolase fold
HPEIFLPB_01729 4.92e-266 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HPEIFLPB_01730 2.04e-129 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
HPEIFLPB_01731 1.03e-306 - - - L - - - Phage integrase, N-terminal SAM-like domain
HPEIFLPB_01732 2.16e-35 - - - K - - - Transcriptional regulator
HPEIFLPB_01735 4.73e-31 - - - - - - - -
HPEIFLPB_01737 7.76e-297 - - - S - - - Protein of unknown function DUF262
HPEIFLPB_01738 1.27e-64 - - - - - - - -
HPEIFLPB_01739 7.91e-132 - - - S - - - Virulence protein RhuM family
HPEIFLPB_01740 3.36e-06 - - - - - - - -
HPEIFLPB_01743 2.18e-107 - - - - - - - -
HPEIFLPB_01744 1.06e-50 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HPEIFLPB_01747 1.83e-49 - - - - - - - -
HPEIFLPB_01749 7.61e-47 - - - - - - - -
HPEIFLPB_01751 6.89e-119 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
HPEIFLPB_01752 0.0 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
HPEIFLPB_01753 2.01e-192 - - - K - - - Transcriptional regulator
HPEIFLPB_01754 1.3e-36 - - - - - - - -
HPEIFLPB_01755 1.52e-106 - - - V - - - HNH endonuclease
HPEIFLPB_01756 5.38e-142 - - - A ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HPEIFLPB_01758 8.37e-66 - - - - - - - -
HPEIFLPB_01760 1.19e-180 - - - - - - - -
HPEIFLPB_01761 1.27e-46 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
HPEIFLPB_01762 4.2e-96 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
HPEIFLPB_01764 5.69e-44 - - - K - - - Transcriptional regulator
HPEIFLPB_01767 1.14e-86 - - - - ko:K07451 - ko00000,ko01000,ko02048 -
HPEIFLPB_01768 1.41e-145 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
HPEIFLPB_01769 7.62e-288 - - - S - - - HipA-like C-terminal domain
HPEIFLPB_01770 3.22e-73 - - - - - - - -
HPEIFLPB_01771 6.77e-87 - - - - - - - -
HPEIFLPB_01772 4.7e-109 - - - - - - - -
HPEIFLPB_01773 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
HPEIFLPB_01774 3.6e-85 - - - - - - - -
HPEIFLPB_01775 5.27e-69 - - - - - - - -
HPEIFLPB_01776 1.6e-52 - - - S - - - Protein of unknown function (DUF2442)
HPEIFLPB_01777 1.07e-82 - - - S - - - Bacterial mobilisation protein (MobC)
HPEIFLPB_01778 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
HPEIFLPB_01779 3.53e-219 - - - S - - - Protein of unknown function (DUF3801)
HPEIFLPB_01780 0.0 - - - - - - - -
HPEIFLPB_01782 0.0 - - - KL - - - Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HPEIFLPB_01783 1.19e-52 - - - - - - - -
HPEIFLPB_01784 7.59e-41 - - - - - - - -
HPEIFLPB_01785 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
HPEIFLPB_01788 7.32e-124 - - - K - - - Helix-turn-helix domain protein
HPEIFLPB_01790 8.15e-225 - - - - ko:K03646 - ko00000,ko02000 -
HPEIFLPB_01792 3.84e-269 - - - M - - - CHAP domain
HPEIFLPB_01793 0.0 - - - U - - - type IV secretory pathway VirB4
HPEIFLPB_01794 6.15e-84 - - - S - - - PrgI family protein
HPEIFLPB_01795 9.88e-180 - - - - - - - -
HPEIFLPB_01796 5.33e-36 - - - - - - - -
HPEIFLPB_01797 0.0 - - - D - - - Cell surface antigen C-terminus
HPEIFLPB_01798 8.18e-156 - - - S - - - cobalamin synthesis protein
HPEIFLPB_01799 2.64e-63 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
HPEIFLPB_01800 4.85e-65 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPEIFLPB_01801 7.57e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HPEIFLPB_01802 3.05e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
HPEIFLPB_01803 6.34e-33 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
HPEIFLPB_01804 1.24e-258 - - - S ko:K07089 - ko00000 Predicted permease
HPEIFLPB_01805 2.62e-197 - - - S - - - TIGRFAM TIGR03943 family protein
HPEIFLPB_01806 3.79e-61 - - - - - - - -
HPEIFLPB_01807 2.88e-96 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HPEIFLPB_01808 5.14e-291 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPEIFLPB_01809 5.14e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPEIFLPB_01810 2.49e-229 yogA - - C - - - Zinc-binding dehydrogenase
HPEIFLPB_01811 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPEIFLPB_01813 1.32e-57 - - - S ko:K06990 - ko00000,ko04812 Memo-like protein
HPEIFLPB_01814 7.34e-290 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HPEIFLPB_01815 3.88e-206 - - - K - - - Helix-turn-helix domain, rpiR family
HPEIFLPB_01816 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPEIFLPB_01817 3.55e-313 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
HPEIFLPB_01818 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPEIFLPB_01819 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
HPEIFLPB_01820 2.63e-121 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPEIFLPB_01822 2.57e-118 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPEIFLPB_01823 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HPEIFLPB_01824 4.9e-283 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HPEIFLPB_01825 3.54e-242 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HPEIFLPB_01826 1.03e-141 - - - - - - - -
HPEIFLPB_01827 3.23e-70 - - - M - - - Belongs to the glycosyl hydrolase 30 family
HPEIFLPB_01828 4.45e-21 - - - - - - - -
HPEIFLPB_01830 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HPEIFLPB_01831 6.36e-160 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPEIFLPB_01832 6.07e-100 - - - S - - - CRISPR-associated protein (Cas_Csn2)
HPEIFLPB_01833 6.07e-29 - - - L - - - Transposase, Mutator family
HPEIFLPB_01834 0.0 - - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
HPEIFLPB_01835 0.0 - - - S - - - Tetratricopeptide repeat
HPEIFLPB_01836 2.18e-266 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPEIFLPB_01837 5.96e-167 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HPEIFLPB_01838 1.48e-214 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPEIFLPB_01839 4.62e-200 - - - L - - - Transposase, Mutator family
HPEIFLPB_01840 4.72e-71 - - - L - - - PFAM Integrase catalytic
HPEIFLPB_01841 1.64e-53 - - - L - - - transposition
HPEIFLPB_01842 9.39e-170 - - - L - - - transposase activity
HPEIFLPB_01845 7.6e-126 - - - - - - - -
HPEIFLPB_01846 7.23e-85 - - - D - - - MobA/MobL family
HPEIFLPB_01847 9e-64 - - - L ko:K07483 - ko00000 Transposase
HPEIFLPB_01848 1.35e-183 tnp3521a2 - - L - - - Integrase core domain
HPEIFLPB_01849 4.61e-189 - - - U - - - Relaxase mobilization nuclease domain protein
HPEIFLPB_01850 4.78e-42 - - - S - - - Psort location Cytoplasmic, score 8.96
HPEIFLPB_01851 1.85e-62 - - - S - - - Psort location Cytoplasmic, score 8.96
HPEIFLPB_01852 4.85e-185 istB - - L - - - IstB-like ATP binding protein
HPEIFLPB_01853 0.0 - - - L - - - PFAM Integrase catalytic
HPEIFLPB_01854 2.32e-23 - - - L - - - Transposase and inactivated derivatives IS30 family
HPEIFLPB_01855 3.62e-245 - - - M - - - Glycosyltransferase like family 2
HPEIFLPB_01856 1.58e-201 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family
HPEIFLPB_01857 2.8e-27 - - - - - - - -
HPEIFLPB_01858 5.65e-120 - - - - ko:K03646 - ko00000,ko02000 -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)