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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HECMCFGC_00001	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HECMCFGC_00002	1.08e-214	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
HECMCFGC_00004	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HECMCFGC_00005	4.12e-254	-	-	-	K	-	-	-	WYL domain
HECMCFGC_00006	5.85e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HECMCFGC_00007	2.85e-115	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HECMCFGC_00008	5.75e-90	-	-	-	V	-	-	-	DivIVA protein
HECMCFGC_00009	1.99e-59	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HECMCFGC_00010	1.42e-91	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HECMCFGC_00011	8.65e-275	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HECMCFGC_00012	2.02e-316	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HECMCFGC_00013	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HECMCFGC_00014	8.24e-159	-	-	-	-	-	-	-	-
HECMCFGC_00015	2.91e-179	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HECMCFGC_00016	6.27e-136	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HECMCFGC_00017	1.39e-88	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HECMCFGC_00018	2.71e-125	-	-	-	-	-	-	-	-
HECMCFGC_00019	1.22e-201	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HECMCFGC_00020	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HECMCFGC_00021	7.06e-291	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
HECMCFGC_00022	6.39e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HECMCFGC_00023	1.64e-81	-	-	-	S	-	-	-	Thiamine-binding protein
HECMCFGC_00024	0.0	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HECMCFGC_00025	6.34e-183	-	-	-	T	-	-	-	Histidine kinase
HECMCFGC_00026	1.17e-48	-	-	-	-	-	-	-	-
HECMCFGC_00027	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
HECMCFGC_00028	8.6e-250	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_00029	6.97e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HECMCFGC_00030	3.41e-107	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HECMCFGC_00031	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HECMCFGC_00032	1.33e-180	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HECMCFGC_00033	1.87e-48	-	-	-	C	-	-	-	Putative TM nitroreductase
HECMCFGC_00034	2.9e-118	-	-	-	C	-	-	-	Putative TM nitroreductase
HECMCFGC_00035	2.06e-251	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HECMCFGC_00036	6.4e-131	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HECMCFGC_00037	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_00038	4.67e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HECMCFGC_00039	1.66e-70	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HECMCFGC_00040	1.59e-67	-	-	-	-	-	-	-	-
HECMCFGC_00041	6.69e-238	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HECMCFGC_00042	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECMCFGC_00043	1.1e-39	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HECMCFGC_00045	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HECMCFGC_00046	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HECMCFGC_00047	3.61e-255	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HECMCFGC_00049	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HECMCFGC_00050	4.62e-145	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HECMCFGC_00051	0.0	-	-	-	I	-	-	-	PAP2 superfamily
HECMCFGC_00052	5.19e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00053	1.21e-143	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00054	2.13e-187	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HECMCFGC_00055	5.24e-195	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HECMCFGC_00056	3.02e-130	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HECMCFGC_00057	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HECMCFGC_00058	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HECMCFGC_00059	1.45e-314	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HECMCFGC_00060	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HECMCFGC_00061	1.91e-183	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
HECMCFGC_00062	0.0	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HECMCFGC_00064	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
HECMCFGC_00065	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HECMCFGC_00066	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HECMCFGC_00067	2.69e-229	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HECMCFGC_00068	1.3e-241	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HECMCFGC_00069	1.75e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HECMCFGC_00070	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HECMCFGC_00071	1.23e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HECMCFGC_00072	2.67e-148	-	-	-	-	-	-	-	-
HECMCFGC_00073	1.33e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HECMCFGC_00074	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HECMCFGC_00075	1.54e-51	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HECMCFGC_00076	8.87e-122	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HECMCFGC_00077	2.82e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HECMCFGC_00078	2.43e-244	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HECMCFGC_00079	6.59e-209	-	-	-	S	-	-	-	Protein of unknown function DUF58
HECMCFGC_00080	3.26e-119	-	-	-	-	-	-	-	-
HECMCFGC_00081	6.19e-241	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HECMCFGC_00082	4.05e-211	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HECMCFGC_00083	4.98e-75	-	-	-	-	-	-	-	-
HECMCFGC_00084	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HECMCFGC_00085	2.13e-143	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HECMCFGC_00086	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HECMCFGC_00087	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HECMCFGC_00088	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HECMCFGC_00089	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HECMCFGC_00090	8.43e-16	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HECMCFGC_00091	4.8e-224	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HECMCFGC_00092	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HECMCFGC_00093	1.06e-173	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
HECMCFGC_00094	4.16e-229	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
HECMCFGC_00095	2.2e-62	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECMCFGC_00096	6.62e-105	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HECMCFGC_00097	3.67e-93	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HECMCFGC_00098	0.0	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
HECMCFGC_00099	1.63e-172	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HECMCFGC_00100	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HECMCFGC_00101	9.75e-162	-	-	-	S	-	-	-	SNARE associated Golgi protein
HECMCFGC_00102	1.37e-152	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HECMCFGC_00103	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HECMCFGC_00104	2.4e-168	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HECMCFGC_00105	5.49e-237	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HECMCFGC_00106	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HECMCFGC_00107	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HECMCFGC_00108	4.79e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HECMCFGC_00109	1.84e-189	-	-	-	G	-	-	-	Fic/DOC family
HECMCFGC_00111	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HECMCFGC_00114	3.66e-283	-	-	-	K	-	-	-	Putative DNA-binding domain
HECMCFGC_00115	6.42e-86	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HECMCFGC_00116	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HECMCFGC_00117	2.33e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HECMCFGC_00118	4.01e-201	-	-	-	C	ko:K03326	-	ko00000,ko02000	C4-dicarboxylate anaerobic carrier
HECMCFGC_00119	1.99e-131	rihA	-	-	F	ko:K01250,ko:K12700	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HECMCFGC_00120	4.51e-56	-	-	-	K	-	-	-	acetyltransferase
HECMCFGC_00121	7.11e-159	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_00122	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HECMCFGC_00123	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_00124	1.18e-115	-	-	-	K	-	-	-	MarR family
HECMCFGC_00125	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HECMCFGC_00126	1.39e-110	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_00127	2.51e-142	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HECMCFGC_00128	1.27e-309	-	-	-	S	ko:K06978	-	ko00000	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
HECMCFGC_00129	1.91e-204	-	-	-	G	-	-	-	Major Facilitator Superfamily
HECMCFGC_00130	3.26e-94	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_00131	7.42e-49	-	-	-	-	-	-	-	-
HECMCFGC_00132	3.99e-301	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HECMCFGC_00133	1.26e-91	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HECMCFGC_00134	1.18e-60	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HECMCFGC_00135	1.07e-88	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HECMCFGC_00136	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HECMCFGC_00137	3e-45	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_00138	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HECMCFGC_00139	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HECMCFGC_00140	9e-172	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HECMCFGC_00141	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HECMCFGC_00142	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HECMCFGC_00143	1.02e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HECMCFGC_00144	1.51e-121	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
HECMCFGC_00145	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HECMCFGC_00146	3.47e-90	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HECMCFGC_00147	7.41e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HECMCFGC_00149	2.25e-264	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HECMCFGC_00150	2.49e-230	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HECMCFGC_00151	2.59e-298	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HECMCFGC_00152	6.12e-257	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HECMCFGC_00153	1.24e-114	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HECMCFGC_00154	1.5e-129	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HECMCFGC_00155	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
HECMCFGC_00156	3.06e-219	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HECMCFGC_00157	9.67e-317	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HECMCFGC_00158	2.07e-191	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HECMCFGC_00159	1.68e-198	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HECMCFGC_00160	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HECMCFGC_00161	1.33e-151	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HECMCFGC_00162	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HECMCFGC_00163	1.2e-196	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HECMCFGC_00164	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HECMCFGC_00165	2.24e-155	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HECMCFGC_00166	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HECMCFGC_00167	1.44e-276	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HECMCFGC_00168	3.41e-152	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HECMCFGC_00169	4.8e-159	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_00170	6.71e-206	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HECMCFGC_00171	3.07e-241	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HECMCFGC_00172	1.08e-196	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HECMCFGC_00173	4.61e-272	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HECMCFGC_00174	1.86e-211	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HECMCFGC_00175	5.78e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HECMCFGC_00176	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HECMCFGC_00178	2.25e-122	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HECMCFGC_00179	2.4e-187	-	-	-	-	-	-	-	-
HECMCFGC_00180	4.33e-95	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HECMCFGC_00181	7.01e-210	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HECMCFGC_00182	1.6e-21	-	-	-	EGP	-	-	-	Major facilitator superfamily
HECMCFGC_00183	2.49e-111	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HECMCFGC_00184	3.25e-223	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HECMCFGC_00186	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECMCFGC_00187	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HECMCFGC_00188	2.45e-215	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HECMCFGC_00189	2.23e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HECMCFGC_00190	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HECMCFGC_00191	4.66e-199	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HECMCFGC_00192	3.65e-126	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HECMCFGC_00193	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HECMCFGC_00194	2.66e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HECMCFGC_00195	2.63e-265	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HECMCFGC_00196	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HECMCFGC_00197	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HECMCFGC_00198	8.2e-246	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_00199	8.71e-299	-	-	-	M	-	-	-	Glycosyl transferase family 21
HECMCFGC_00200	0.0	-	-	-	S	-	-	-	AI-2E family transporter
HECMCFGC_00201	2.21e-226	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HECMCFGC_00202	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HECMCFGC_00203	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
HECMCFGC_00206	6.18e-209	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HECMCFGC_00208	9.38e-15	-	-	-	L	-	-	-	Phage integrase family
HECMCFGC_00209	9.78e-16	-	-	-	M	-	-	-	Cell surface antigen C-terminus
HECMCFGC_00210	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HECMCFGC_00211	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HECMCFGC_00212	1.19e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HECMCFGC_00213	1.18e-225	-	-	-	-	-	-	-	-
HECMCFGC_00214	1.17e-161	-	-	-	V	-	-	-	ABC transporter
HECMCFGC_00215	1.91e-239	-	-	-	V	-	-	-	Putative peptidoglycan binding domain
HECMCFGC_00216	8.57e-150	-	-	-	-	-	-	-	-
HECMCFGC_00217	1.78e-78	-	-	-	-	-	-	-	-
HECMCFGC_00218	1.19e-152	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HECMCFGC_00219	1.98e-269	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	GHKL domain
HECMCFGC_00220	2.92e-09	-	-	-	L	-	-	-	Helix-turn-helix domain
HECMCFGC_00221	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00222	5.69e-280	-	-	-	GK	-	-	-	ROK family
HECMCFGC_00223	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HECMCFGC_00224	7.34e-12	-	-	-	L	-	-	-	HTH-like domain
HECMCFGC_00225	2.94e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HECMCFGC_00226	5.93e-265	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HECMCFGC_00227	3.41e-143	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_00228	8.98e-16	-	-	-	E	-	-	-	AzlC protein
HECMCFGC_00229	1.74e-126	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HECMCFGC_00230	2.94e-162	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HECMCFGC_00231	1.73e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HECMCFGC_00232	1.85e-95	-	-	-	O	-	-	-	OsmC-like protein
HECMCFGC_00233	1.36e-241	-	-	-	T	-	-	-	Universal stress protein family
HECMCFGC_00234	9.3e-144	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HECMCFGC_00235	1.76e-139	-	-	-	M	-	-	-	NlpC/P60 family
HECMCFGC_00236	8.48e-216	-	-	-	S	-	-	-	CHAP domain
HECMCFGC_00237	4.57e-268	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HECMCFGC_00238	2.3e-44	-	-	-	-	-	-	-	-
HECMCFGC_00239	1.24e-236	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HECMCFGC_00240	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HECMCFGC_00241	3.9e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HECMCFGC_00242	9.25e-221	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HECMCFGC_00243	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HECMCFGC_00245	1.39e-278	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HECMCFGC_00246	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HECMCFGC_00247	2.16e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HECMCFGC_00248	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HECMCFGC_00249	7.41e-103	-	-	-	-	-	-	-	-
HECMCFGC_00250	0.0	pspC	-	-	KT	-	-	-	PspC domain
HECMCFGC_00251	1.11e-298	tcsS3	-	-	KT	-	-	-	PspC domain
HECMCFGC_00252	2.89e-152	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HECMCFGC_00253	4.59e-226	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HECMCFGC_00254	1.7e-261	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
HECMCFGC_00255	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HECMCFGC_00256	5.76e-217	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HECMCFGC_00257	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00258	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00260	2.27e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HECMCFGC_00261	7.3e-268	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HECMCFGC_00262	1.58e-209	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HECMCFGC_00263	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
HECMCFGC_00264	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HECMCFGC_00265	4.45e-252	-	-	-	S	-	-	-	Protein conserved in bacteria
HECMCFGC_00266	1.74e-96	-	-	-	K	-	-	-	Transcriptional regulator
HECMCFGC_00267	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HECMCFGC_00268	6.4e-241	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HECMCFGC_00269	4.47e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HECMCFGC_00270	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HECMCFGC_00271	4.12e-133	-	-	-	-	-	-	-	-
HECMCFGC_00272	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HECMCFGC_00273	1.75e-279	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HECMCFGC_00274	1.5e-277	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HECMCFGC_00275	3.5e-107	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HECMCFGC_00276	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HECMCFGC_00277	1.3e-242	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HECMCFGC_00278	3.37e-163	-	-	-	-	-	-	-	-
HECMCFGC_00279	3.06e-96	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_00281	1.25e-195	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HECMCFGC_00283	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HECMCFGC_00284	3.63e-218	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HECMCFGC_00285	2.36e-90	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HECMCFGC_00286	8.1e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HECMCFGC_00287	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HECMCFGC_00288	1.16e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HECMCFGC_00289	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HECMCFGC_00290	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HECMCFGC_00291	2.57e-128	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HECMCFGC_00292	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HECMCFGC_00293	1.07e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HECMCFGC_00294	4.64e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HECMCFGC_00295	2.25e-129	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HECMCFGC_00296	3.09e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HECMCFGC_00297	7.72e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HECMCFGC_00298	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HECMCFGC_00299	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HECMCFGC_00300	1.95e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HECMCFGC_00301	5.4e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HECMCFGC_00302	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HECMCFGC_00303	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HECMCFGC_00304	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HECMCFGC_00305	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HECMCFGC_00306	1.85e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HECMCFGC_00307	1.09e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HECMCFGC_00308	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HECMCFGC_00309	3.85e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HECMCFGC_00310	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HECMCFGC_00311	2.31e-149	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HECMCFGC_00312	1.11e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HECMCFGC_00313	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HECMCFGC_00314	2.46e-42	-	-	-	L	-	-	-	Transposase
HECMCFGC_00315	2.61e-48	-	-	-	L	-	-	-	Transposase DDE domain
HECMCFGC_00316	1.26e-102	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HECMCFGC_00317	2.91e-174	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HECMCFGC_00318	9.55e-121	-	-	-	S	-	-	-	YwiC-like protein
HECMCFGC_00319	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HECMCFGC_00320	6.16e-283	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HECMCFGC_00321	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HECMCFGC_00322	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HECMCFGC_00323	5.33e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HECMCFGC_00324	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HECMCFGC_00325	9.47e-152	-	-	-	-	-	-	-	-
HECMCFGC_00326	6.88e-144	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HECMCFGC_00327	1.78e-228	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HECMCFGC_00328	2.29e-279	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HECMCFGC_00329	1.16e-311	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HECMCFGC_00330	4.17e-204	-	-	-	U	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00331	4.88e-208	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00332	1.81e-310	-	-	-	G	ko:K02027,ko:K10227	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00333	2.12e-276	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_00334	6.9e-29	-	-	-	-	-	-	-	-
HECMCFGC_00336	1.34e-83	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HECMCFGC_00337	7.95e-28	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HECMCFGC_00338	9.54e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HECMCFGC_00339	8.47e-284	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HECMCFGC_00340	4.51e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HECMCFGC_00341	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HECMCFGC_00342	1.03e-281	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HECMCFGC_00343	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HECMCFGC_00347	1.73e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HECMCFGC_00348	2.09e-182	-	-	-	-	-	-	-	-
HECMCFGC_00349	2.1e-112	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HECMCFGC_00350	1.03e-78	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HECMCFGC_00351	6.24e-43	-	-	-	S	-	-	-	Putative regulatory protein
HECMCFGC_00352	2.2e-134	-	-	-	NO	-	-	-	SAF
HECMCFGC_00353	6.79e-24	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HECMCFGC_00354	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HECMCFGC_00355	4.98e-270	-	-	-	T	-	-	-	Forkhead associated domain
HECMCFGC_00356	1.06e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HECMCFGC_00357	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HECMCFGC_00358	1.95e-121	-	-	-	S	-	-	-	alpha beta
HECMCFGC_00359	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HECMCFGC_00360	4.51e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HECMCFGC_00361	1.86e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HECMCFGC_00362	6.67e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HECMCFGC_00363	2.32e-260	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HECMCFGC_00364	1.5e-182	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HECMCFGC_00365	1.97e-277	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HECMCFGC_00366	2.91e-307	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HECMCFGC_00367	1.48e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HECMCFGC_00368	9.45e-300	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HECMCFGC_00369	2.3e-277	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HECMCFGC_00370	1.97e-111	-	-	-	G	ko:K12112	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001	YhcH YjgK YiaL family protein
HECMCFGC_00371	0.0	-	3.2.1.23	-	G	ko:K12111	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HECMCFGC_00372	6.14e-147	pgmB	5.4.2.6	-	S	ko:K01838,ko:K04844	ko00500,map00500	ko00000,ko00001,ko01000	phosphonoacetaldehyde hydrolase activity
HECMCFGC_00373	5.4e-199	-	-	-	EG	-	-	-	EamA-like transporter family
HECMCFGC_00374	0.0	kojP	2.4.1.230, 2.4.1.64	GH65	G	ko:K05342,ko:K10231	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HECMCFGC_00375	7.49e-196	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00376	1.41e-216	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00377	9.7e-302	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00378	1.59e-241	-	-	-	K	-	-	-	Periplasmic binding protein domain
HECMCFGC_00379	3.47e-128	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HECMCFGC_00380	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HECMCFGC_00381	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HECMCFGC_00382	1.23e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
HECMCFGC_00383	6.14e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HECMCFGC_00384	3.28e-194	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HECMCFGC_00385	3.38e-251	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HECMCFGC_00386	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HECMCFGC_00387	1.68e-225	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HECMCFGC_00388	1.93e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HECMCFGC_00389	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HECMCFGC_00390	1.05e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HECMCFGC_00391	1.54e-248	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HECMCFGC_00392	1.71e-300	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HECMCFGC_00393	4.61e-168	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECMCFGC_00394	5.87e-86	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
HECMCFGC_00395	2.07e-71	-	-	-	L	-	-	-	RelB antitoxin
HECMCFGC_00396	1.18e-34	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
HECMCFGC_00397	8.53e-246	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECMCFGC_00398	5.71e-68	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HECMCFGC_00402	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
HECMCFGC_00403	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HECMCFGC_00404	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HECMCFGC_00405	9.64e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HECMCFGC_00406	4.51e-210	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HECMCFGC_00407	0.0	-	-	-	-	-	-	-	-
HECMCFGC_00408	8.8e-210	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HECMCFGC_00409	1.75e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HECMCFGC_00410	5e-96	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HECMCFGC_00411	9.46e-175	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HECMCFGC_00412	4.95e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HECMCFGC_00414	2.77e-292	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HECMCFGC_00415	5.08e-300	-	-	-	G	-	-	-	polysaccharide deacetylase
HECMCFGC_00416	7.5e-250	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HECMCFGC_00417	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HECMCFGC_00418	1.44e-51	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HECMCFGC_00419	1.01e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HECMCFGC_00420	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HECMCFGC_00421	8.53e-294	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HECMCFGC_00422	9.14e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HECMCFGC_00423	7.01e-213	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HECMCFGC_00424	1.15e-190	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
HECMCFGC_00425	1.93e-270	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HECMCFGC_00426	5.27e-191	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HECMCFGC_00427	0.0	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HECMCFGC_00428	4.75e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HECMCFGC_00429	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HECMCFGC_00430	2.29e-173	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_00431	2.44e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HECMCFGC_00432	1.58e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HECMCFGC_00433	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HECMCFGC_00434	1.6e-231	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HECMCFGC_00435	4.56e-303	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HECMCFGC_00436	7.15e-62	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HECMCFGC_00437	4.64e-74	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HECMCFGC_00438	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HECMCFGC_00439	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HECMCFGC_00440	9.05e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_00441	2.22e-279	-	-	-	G	-	-	-	Transmembrane secretion effector
HECMCFGC_00442	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HECMCFGC_00443	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HECMCFGC_00444	2.62e-201	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HECMCFGC_00445	2.47e-154	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00446	1.32e-179	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00447	6.1e-135	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HECMCFGC_00448	4.6e-169	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_00449	4.34e-282	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HECMCFGC_00450	9.38e-48	-	-	-	T	-	-	-	Histidine kinase
HECMCFGC_00451	7.03e-14	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HECMCFGC_00452	1.62e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HECMCFGC_00453	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HECMCFGC_00454	5.82e-182	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HECMCFGC_00455	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HECMCFGC_00456	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HECMCFGC_00457	8.73e-300	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HECMCFGC_00458	6.93e-160	-	-	-	-	-	-	-	-
HECMCFGC_00459	0.0	-	-	-	G	-	-	-	N-terminal domain of (some) glycogen debranching enzymes
HECMCFGC_00460	3e-178	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00461	3.73e-267	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00462	7.97e-263	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00463	4.89e-164	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_00464	9.47e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HECMCFGC_00465	1.05e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HECMCFGC_00466	3.12e-275	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HECMCFGC_00467	2.9e-278	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HECMCFGC_00469	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HECMCFGC_00470	6.65e-208	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HECMCFGC_00471	1.25e-203	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HECMCFGC_00472	1.48e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
HECMCFGC_00473	5.02e-209	-	-	-	-	-	-	-	-
HECMCFGC_00474	3.83e-296	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HECMCFGC_00475	1.28e-81	-	-	-	K	-	-	-	Helix-turn-helix domain
HECMCFGC_00476	6.56e-10	-	-	-	S	-	-	-	PIN domain
HECMCFGC_00477	1.51e-58	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
HECMCFGC_00478	4.96e-70	-	-	-	G	-	-	-	Branched-chain amino acid transport system / permease component
HECMCFGC_00479	4.36e-97	-	-	-	P	-	-	-	branched-chain amino acid ABC transporter, permease protein
HECMCFGC_00480	3.85e-144	-	-	-	G	-	-	-	ATPases associated with a variety of cellular activities
HECMCFGC_00481	1.29e-98	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
HECMCFGC_00482	6.75e-212	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HECMCFGC_00483	1.14e-89	xylR	-	-	GK	-	-	-	ROK family
HECMCFGC_00484	2.44e-56	-	-	-	-	-	-	-	-
HECMCFGC_00485	3.8e-252	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HECMCFGC_00486	4.15e-233	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
HECMCFGC_00487	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HECMCFGC_00488	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
HECMCFGC_00489	7.81e-207	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_00490	1.16e-152	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HECMCFGC_00491	5.34e-215	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HECMCFGC_00492	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HECMCFGC_00493	1.45e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HECMCFGC_00494	0.0	-	-	-	-	-	-	-	-
HECMCFGC_00495	7.05e-214	-	-	-	M	-	-	-	Glycosyl transferase family 2
HECMCFGC_00496	3.74e-39	-	-	-	M	-	-	-	nuclease
HECMCFGC_00497	1.1e-98	-	-	-	M	-	-	-	L,D-transpeptidase catalytic domain
HECMCFGC_00498	1.34e-10	-	-	-	M	-	-	-	Peptidase_C39 like family
HECMCFGC_00499	2.05e-219	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HECMCFGC_00500	1.61e-309	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HECMCFGC_00501	0.0	-	-	-	V	-	-	-	ABC transporter permease
HECMCFGC_00502	1.8e-241	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HECMCFGC_00503	4.31e-181	-	-	-	T	ko:K06950	-	ko00000	HD domain
HECMCFGC_00504	2.99e-206	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HECMCFGC_00505	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HECMCFGC_00506	1.11e-236	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HECMCFGC_00507	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HECMCFGC_00508	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HECMCFGC_00509	1.62e-73	-	-	-	G	-	-	-	domain, Protein
HECMCFGC_00510	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HECMCFGC_00511	2.81e-79	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HECMCFGC_00512	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HECMCFGC_00513	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HECMCFGC_00514	1.66e-224	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HECMCFGC_00515	3.78e-223	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00516	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HECMCFGC_00517	7.04e-63	-	-	-	-	-	-	-	-
HECMCFGC_00518	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HECMCFGC_00519	7.57e-156	-	-	-	-	-	-	-	-
HECMCFGC_00520	5.49e-238	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HECMCFGC_00522	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HECMCFGC_00523	3.04e-231	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HECMCFGC_00524	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HECMCFGC_00525	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_00526	2.33e-120	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HECMCFGC_00527	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HECMCFGC_00528	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HECMCFGC_00529	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HECMCFGC_00530	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HECMCFGC_00531	2.24e-134	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HECMCFGC_00532	4.49e-196	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECMCFGC_00533	2.71e-199	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00534	8.42e-237	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HECMCFGC_00535	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00536	1.29e-132	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HECMCFGC_00537	6.43e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HECMCFGC_00538	1.19e-156	nfrA	-	-	C	-	-	-	Nitroreductase family
HECMCFGC_00539	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HECMCFGC_00540	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HECMCFGC_00541	2.58e-54	-	-	-	-	-	-	-	-
HECMCFGC_00542	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00543	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HECMCFGC_00544	9.23e-101	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HECMCFGC_00545	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HECMCFGC_00546	7.59e-268	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_00547	1.35e-204	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HECMCFGC_00548	1.96e-224	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HECMCFGC_00549	8.64e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HECMCFGC_00550	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00551	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_00552	2.2e-227	-	-	-	L	-	-	-	HTH-like domain
HECMCFGC_00553	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HECMCFGC_00556	7.64e-226	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HECMCFGC_00557	3.62e-170	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HECMCFGC_00558	3.84e-186	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HECMCFGC_00559	2.83e-316	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HECMCFGC_00560	1.58e-151	-	-	-	-	-	-	-	-
HECMCFGC_00561	6.1e-101	-	-	-	K	-	-	-	MerR, DNA binding
HECMCFGC_00562	3.1e-247	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HECMCFGC_00563	6.02e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HECMCFGC_00564	9.97e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HECMCFGC_00565	2.55e-156	-	-	-	-	-	-	-	-
HECMCFGC_00566	3.1e-149	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HECMCFGC_00567	4.87e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HECMCFGC_00568	6.09e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HECMCFGC_00569	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HECMCFGC_00570	8.22e-120	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HECMCFGC_00571	1.25e-56	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
HECMCFGC_00572	8.06e-96	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
HECMCFGC_00573	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HECMCFGC_00574	2.14e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HECMCFGC_00575	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HECMCFGC_00576	3.18e-207	-	-	-	P	-	-	-	Cation efflux family
HECMCFGC_00577	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HECMCFGC_00578	1.9e-270	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HECMCFGC_00579	5.48e-84	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HECMCFGC_00580	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HECMCFGC_00581	1.48e-137	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HECMCFGC_00582	8.69e-257	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HECMCFGC_00583	2.76e-214	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HECMCFGC_00584	7.61e-20	-	-	-	-	-	-	-	-
HECMCFGC_00585	2.36e-310	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HECMCFGC_00586	6.99e-13	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HECMCFGC_00587	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HECMCFGC_00588	4.3e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HECMCFGC_00589	6.33e-101	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HECMCFGC_00590	9.53e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_00591	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HECMCFGC_00592	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HECMCFGC_00593	9.18e-145	-	-	-	-	-	-	-	-
HECMCFGC_00594	1.17e-111	-	-	-	-	-	-	-	-
HECMCFGC_00596	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HECMCFGC_00597	6.63e-221	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
HECMCFGC_00598	8.61e-104	-	-	-	-	-	-	-	-
HECMCFGC_00600	2.35e-139	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HECMCFGC_00601	3.31e-91	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HECMCFGC_00602	2.71e-107	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HECMCFGC_00603	1.94e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HECMCFGC_00604	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HECMCFGC_00605	2.01e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_00606	5.24e-46	-	-	-	L	-	-	-	Transposase, Mutator family
HECMCFGC_00607	2.5e-298	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HECMCFGC_00608	1.88e-226	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00609	1.85e-211	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00610	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00611	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HECMCFGC_00612	3.49e-248	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_00613	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HECMCFGC_00614	2.84e-172	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HECMCFGC_00615	8.55e-16	-	-	-	L	-	-	-	Transposase DDE domain
HECMCFGC_00616	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HECMCFGC_00617	2.65e-175	-	-	-	M	-	-	-	Mechanosensitive ion channel
HECMCFGC_00618	7.19e-237	-	-	-	S	-	-	-	CAAX protease self-immunity
HECMCFGC_00619	1.85e-302	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HECMCFGC_00620	1.18e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00621	9.78e-207	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00622	1.06e-278	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_00623	1.73e-292	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HECMCFGC_00624	1.38e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HECMCFGC_00625	4.4e-232	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HECMCFGC_00626	3.27e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HECMCFGC_00629	6.45e-151	-	-	-	S	-	-	-	CYTH
HECMCFGC_00630	1.26e-219	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HECMCFGC_00631	2.31e-232	-	-	-	-	-	-	-	-
HECMCFGC_00632	2.46e-248	-	-	-	-	-	-	-	-
HECMCFGC_00633	5.97e-215	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HECMCFGC_00634	3.52e-165	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HECMCFGC_00635	3.62e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HECMCFGC_00636	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HECMCFGC_00637	2.07e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HECMCFGC_00638	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HECMCFGC_00639	4.49e-195	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HECMCFGC_00640	1.05e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HECMCFGC_00641	1.65e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HECMCFGC_00642	2.8e-189	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HECMCFGC_00643	4.78e-261	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HECMCFGC_00646	3.99e-54	-	-	-	-	-	-	-	-
HECMCFGC_00647	1.8e-31	-	-	-	-	-	-	-	-
HECMCFGC_00648	6.07e-165	-	-	-	L	-	-	-	HNH endonuclease
HECMCFGC_00649	2.81e-64	-	-	-	-	-	-	-	-
HECMCFGC_00650	0.0	-	-	-	S	-	-	-	Terminase
HECMCFGC_00651	8.05e-263	-	-	-	S	-	-	-	Phage portal protein
HECMCFGC_00652	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HECMCFGC_00653	6.44e-47	-	-	-	-	-	-	-	-
HECMCFGC_00654	1.96e-35	-	-	-	-	-	-	-	-
HECMCFGC_00655	1.83e-62	-	-	-	-	-	-	-	-
HECMCFGC_00656	9.9e-59	-	-	-	-	-	-	-	-
HECMCFGC_00658	1.22e-305	-	-	-	NT	-	-	-	phage tail tape measure protein
HECMCFGC_00659	6.32e-135	-	-	-	-	-	-	-	-
HECMCFGC_00662	1.41e-13	-	-	-	-	-	-	-	-
HECMCFGC_00663	7.54e-98	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HECMCFGC_00664	3.79e-34	-	-	-	-	-	-	-	-
HECMCFGC_00668	3.98e-106	-	-	-	L	-	-	-	Phage integrase family
HECMCFGC_00669	1.6e-31	-	-	-	L	-	-	-	Phage integrase family
HECMCFGC_00670	1.41e-92	-	-	-	L	-	-	-	Phage integrase family
HECMCFGC_00671	5.91e-38	-	-	-	-	-	-	-	-
HECMCFGC_00672	4.69e-72	-	-	-	-	-	-	-	-
HECMCFGC_00673	8.2e-30	-	-	-	-	-	-	-	-
HECMCFGC_00674	4.2e-35	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HECMCFGC_00676	1.24e-90	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
HECMCFGC_00678	0.0	lacZ3	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HECMCFGC_00679	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HECMCFGC_00680	5.03e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_00681	1.67e-152	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HECMCFGC_00682	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
HECMCFGC_00683	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HECMCFGC_00684	9.95e-215	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00685	2.9e-227	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00686	7.12e-196	-	-	-	S	-	-	-	Fic/DOC family
HECMCFGC_00688	4.2e-23	-	-	-	-	-	-	-	-
HECMCFGC_00689	3.39e-55	-	-	-	S	-	-	-	Putative phage holin Dp-1
HECMCFGC_00690	1.31e-10	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HECMCFGC_00691	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
HECMCFGC_00692	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HECMCFGC_00693	1.95e-119	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HECMCFGC_00694	7.1e-113	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HECMCFGC_00695	4.41e-155	-	-	-	-	-	-	-	-
HECMCFGC_00696	2.67e-179	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HECMCFGC_00697	1.2e-162	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HECMCFGC_00698	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HECMCFGC_00699	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HECMCFGC_00700	0.0	-	-	-	S	-	-	-	domain protein
HECMCFGC_00701	7.71e-82	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HECMCFGC_00702	3.47e-63	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HECMCFGC_00703	1.13e-192	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HECMCFGC_00704	1.03e-30	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
HECMCFGC_00705	1.49e-161	-	-	-	L	ko:K07493	-	ko00000	PFAM Transposase, Mutator family
HECMCFGC_00706	5.14e-78	-	-	-	L	-	-	-	Transposase
HECMCFGC_00707	0.0	lacZ3	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HECMCFGC_00708	0.0	-	-	-	G	ko:K16139	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HECMCFGC_00709	1.15e-258	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_00710	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HECMCFGC_00711	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HECMCFGC_00712	0.0	-	3.1.3.2, 3.6.1.27	-	I	ko:K09474,ko:K12685,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	ko00000,ko00001,ko01000,ko01011,ko02000,ko02044	phosphatidate phosphatase activity
HECMCFGC_00713	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HECMCFGC_00714	6.92e-202	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HECMCFGC_00715	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HECMCFGC_00716	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HECMCFGC_00717	7.57e-68	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HECMCFGC_00719	2.07e-69	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HECMCFGC_00720	9.29e-230	-	-	-	-	-	-	-	-
HECMCFGC_00721	5.76e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HECMCFGC_00722	2.98e-217	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HECMCFGC_00723	6.9e-142	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HECMCFGC_00724	2.18e-275	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HECMCFGC_00725	1.64e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HECMCFGC_00726	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HECMCFGC_00727	2.54e-161	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HECMCFGC_00729	4.72e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HECMCFGC_00730	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HECMCFGC_00731	4.09e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HECMCFGC_00732	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HECMCFGC_00733	3.31e-238	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HECMCFGC_00734	1.23e-196	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HECMCFGC_00735	3.57e-225	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
HECMCFGC_00736	3.53e-90	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HECMCFGC_00737	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HECMCFGC_00738	1.27e-47	-	-	-	S	-	-	-	granule-associated protein
HECMCFGC_00739	9.06e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HECMCFGC_00740	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HECMCFGC_00741	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HECMCFGC_00742	3.49e-304	dinF	-	-	V	-	-	-	MatE
HECMCFGC_00743	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HECMCFGC_00744	1.27e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HECMCFGC_00745	1.86e-303	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HECMCFGC_00746	1.38e-232	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HECMCFGC_00747	2.79e-191	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_00748	8.95e-251	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HECMCFGC_00749	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HECMCFGC_00751	0.0	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HECMCFGC_00752	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HECMCFGC_00753	1.04e-247	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HECMCFGC_00754	2.49e-193	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HECMCFGC_00755	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HECMCFGC_00756	0.0	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HECMCFGC_00757	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HECMCFGC_00758	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HECMCFGC_00759	1.62e-130	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HECMCFGC_00760	1.68e-102	-	-	-	S	-	-	-	FMN_bind
HECMCFGC_00761	1.39e-187	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_00762	5.77e-264	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HECMCFGC_00763	9.15e-285	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HECMCFGC_00764	8.28e-291	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
HECMCFGC_00765	5.41e-159	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
HECMCFGC_00766	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
HECMCFGC_00770	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HECMCFGC_00772	3.23e-230	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HECMCFGC_00773	7.3e-289	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HECMCFGC_00774	1.36e-202	-	-	-	-	-	-	-	-
HECMCFGC_00775	5.07e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HECMCFGC_00776	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECMCFGC_00777	1.29e-124	-	-	-	S	-	-	-	GtrA-like protein
HECMCFGC_00778	1.11e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HECMCFGC_00779	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HECMCFGC_00780	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HECMCFGC_00781	1.78e-136	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HECMCFGC_00782	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HECMCFGC_00784	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HECMCFGC_00785	3.67e-137	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_00786	1.78e-263	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HECMCFGC_00787	4.11e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HECMCFGC_00788	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HECMCFGC_00789	6.36e-218	-	-	-	I	-	-	-	PAP2 superfamily
HECMCFGC_00790	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HECMCFGC_00791	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HECMCFGC_00792	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HECMCFGC_00793	1.95e-191	-	-	-	K	-	-	-	FCD
HECMCFGC_00794	6.27e-305	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HECMCFGC_00795	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
HECMCFGC_00796	3.53e-17	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HECMCFGC_00797	3.54e-188	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HECMCFGC_00798	1.5e-230	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HECMCFGC_00799	3.25e-186	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_00800	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HECMCFGC_00801	2.11e-204	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_00802	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HECMCFGC_00803	8.57e-203	-	3.5.1.106	-	I	ko:K15357	ko00760,ko01120,map00760,map01120	ko00000,ko00001,ko00002,ko01000	carboxylic ester hydrolase activity
HECMCFGC_00804	1.2e-162	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HECMCFGC_00805	2.54e-59	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HECMCFGC_00806	4.31e-65	-	-	-	-	-	-	-	-
HECMCFGC_00807	1.1e-129	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HECMCFGC_00808	8.67e-43	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HECMCFGC_00809	2.96e-241	-	-	-	V	-	-	-	VanZ like family
HECMCFGC_00810	2.59e-129	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECMCFGC_00811	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HECMCFGC_00812	2.71e-199	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HECMCFGC_00813	2.61e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
HECMCFGC_00814	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HECMCFGC_00815	4.36e-208	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HECMCFGC_00816	4.91e-239	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HECMCFGC_00817	8.36e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HECMCFGC_00818	5.07e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HECMCFGC_00819	3.56e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HECMCFGC_00820	1.29e-135	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HECMCFGC_00821	4.04e-217	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HECMCFGC_00822	6.08e-61	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HECMCFGC_00823	6.51e-181	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HECMCFGC_00824	2.02e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HECMCFGC_00825	6.38e-143	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECMCFGC_00826	3.74e-85	-	-	-	-	-	-	-	-
HECMCFGC_00827	3.47e-205	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
HECMCFGC_00828	3.46e-50	-	-	-	-	-	-	-	-
HECMCFGC_00829	2.61e-179	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HECMCFGC_00830	3.18e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HECMCFGC_00831	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HECMCFGC_00832	4.22e-70	-	-	-	-	-	-	-	-
HECMCFGC_00833	0.0	-	-	-	K	-	-	-	WYL domain
HECMCFGC_00834	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HECMCFGC_00835	4.56e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HECMCFGC_00837	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HECMCFGC_00838	9.06e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HECMCFGC_00839	4.48e-180	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HECMCFGC_00840	9.09e-46	-	-	-	-	-	-	-	-
HECMCFGC_00841	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HECMCFGC_00842	9.77e-297	-	-	-	-	-	-	-	-
HECMCFGC_00843	5.31e-211	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HECMCFGC_00844	4.18e-282	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HECMCFGC_00845	5.54e-131	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HECMCFGC_00846	1.03e-70	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HECMCFGC_00847	1.5e-254	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HECMCFGC_00848	4.14e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HECMCFGC_00849	4.21e-131	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HECMCFGC_00850	1.19e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HECMCFGC_00851	7.63e-143	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
HECMCFGC_00852	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HECMCFGC_00858	2.17e-169	-	-	-	S	-	-	-	PAC2 family
HECMCFGC_00859	1.51e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HECMCFGC_00860	7.54e-200	-	-	-	G	-	-	-	Fructosamine kinase
HECMCFGC_00861	6.94e-143	-	-	-	L	-	-	-	Phage integrase family
HECMCFGC_00862	6.64e-32	-	-	-	-	-	-	-	-
HECMCFGC_00863	8.95e-129	-	-	-	-	-	-	-	-
HECMCFGC_00864	2.01e-116	-	-	-	T	-	-	-	T5orf172
HECMCFGC_00865	6.48e-35	-	-	-	S	-	-	-	IrrE N-terminal-like domain
HECMCFGC_00869	2.85e-166	-	-	-	K	-	-	-	BRO family, N-terminal domain
HECMCFGC_00874	9.77e-68	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HECMCFGC_00877	7.43e-26	-	-	-	-	-	-	-	-
HECMCFGC_00879	1.42e-212	-	-	-	-	-	-	-	-
HECMCFGC_00880	3.68e-41	-	-	-	L	-	-	-	single-stranded DNA binding
HECMCFGC_00881	7.79e-10	-	-	-	L	-	-	-	single-stranded DNA binding
HECMCFGC_00883	0.0	-	-	-	T	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HECMCFGC_00888	1.75e-112	-	-	-	J	-	-	-	tRNA 5'-leader removal
HECMCFGC_00892	1.69e-32	-	-	-	L	-	-	-	HNH endonuclease
HECMCFGC_00893	4.36e-36	-	-	-	-	-	-	-	-
HECMCFGC_00894	9.56e-230	-	-	-	S	-	-	-	Terminase
HECMCFGC_00895	4.93e-222	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HECMCFGC_00896	5.2e-70	-	-	-	-	-	-	-	-
HECMCFGC_00898	2.14e-60	-	-	-	-	-	-	-	-
HECMCFGC_00899	2.9e-204	-	-	-	S	-	-	-	Phage capsid family
HECMCFGC_00900	5.89e-75	-	-	-	-	-	-	-	-
HECMCFGC_00901	1.21e-55	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
HECMCFGC_00902	1.39e-59	-	-	-	-	-	-	-	-
HECMCFGC_00903	4.55e-27	-	-	-	-	-	-	-	-
HECMCFGC_00904	1.11e-49	-	-	-	-	-	-	-	-
HECMCFGC_00905	2.99e-84	-	-	-	N	-	-	-	domain, Protein
HECMCFGC_00908	1.06e-99	-	-	-	NT	-	-	-	phage tail tape measure protein
HECMCFGC_00910	2.96e-221	-	-	-	S	-	-	-	cellulase activity
HECMCFGC_00912	1.29e-46	-	-	-	-	-	-	-	-
HECMCFGC_00918	4.43e-107	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HECMCFGC_00919	8.96e-25	-	-	-	-	-	-	-	-
HECMCFGC_00920	2.29e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HECMCFGC_00921	4.92e-245	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HECMCFGC_00922	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HECMCFGC_00923	2.71e-259	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HECMCFGC_00924	3.35e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HECMCFGC_00925	2.4e-246	-	-	-	-	-	-	-	-
HECMCFGC_00926	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
HECMCFGC_00927	9.92e-206	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HECMCFGC_00928	2.67e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HECMCFGC_00929	2.51e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HECMCFGC_00930	1.7e-188	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HECMCFGC_00931	4.15e-278	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HECMCFGC_00932	2.86e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HECMCFGC_00933	6.34e-228	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HECMCFGC_00934	4.9e-239	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HECMCFGC_00935	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HECMCFGC_00936	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HECMCFGC_00937	5.84e-296	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HECMCFGC_00940	5.24e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HECMCFGC_00941	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HECMCFGC_00942	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HECMCFGC_00943	1.93e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HECMCFGC_00944	1.55e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HECMCFGC_00945	1.01e-273	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HECMCFGC_00946	1.08e-39	-	-	-	-	-	-	-	-
HECMCFGC_00947	4.64e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HECMCFGC_00948	1.34e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HECMCFGC_00949	2.36e-201	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HECMCFGC_00950	1.74e-223	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HECMCFGC_00951	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HECMCFGC_00952	2.61e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HECMCFGC_00953	4.95e-226	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HECMCFGC_00954	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HECMCFGC_00955	3.45e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HECMCFGC_00956	9.57e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HECMCFGC_00957	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HECMCFGC_00959	4.8e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HECMCFGC_00960	2.22e-257	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HECMCFGC_00961	8.72e-172	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HECMCFGC_00963	5.91e-181	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HECMCFGC_00964	1.99e-187	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
HECMCFGC_00965	2.25e-116	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
HECMCFGC_00966	2.39e-227	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HECMCFGC_00968	1.09e-213	CP_1020	-	-	S	-	-	-	zinc ion binding
HECMCFGC_00969	6.23e-162	-	-	-	S	-	-	-	Plasmid pRiA4b ORF-3-like protein
HECMCFGC_00970	3.23e-39	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	EamA-like transporter family
HECMCFGC_00971	9.83e-12	-	-	-	L	-	-	-	Transposase DDE domain
HECMCFGC_00973	2.43e-272	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
HECMCFGC_00974	1.87e-113	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HECMCFGC_00975	1.22e-181	-	-	-	-	-	-	-	-
HECMCFGC_00976	1.13e-125	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HECMCFGC_00978	4.82e-63	-	-	-	L	-	-	-	Transposase, Mutator family
HECMCFGC_00979	8.71e-261	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HECMCFGC_00981	2.92e-99	-	-	-	G	ko:K02445,ko:K03762	-	ko00000,ko02000	transmembrane transporter activity
HECMCFGC_00983	4.21e-206	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HECMCFGC_00984	1.2e-201	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_00985	7.93e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HECMCFGC_00986	1.7e-106	-	-	-	-	-	-	-	-
HECMCFGC_00987	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
HECMCFGC_00988	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HECMCFGC_00989	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HECMCFGC_00990	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HECMCFGC_00991	9.59e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_00993	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HECMCFGC_00994	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HECMCFGC_00995	4.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HECMCFGC_00996	4.82e-179	-	-	-	S	-	-	-	UPF0126 domain
HECMCFGC_00997	5.58e-192	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
HECMCFGC_00998	2.72e-288	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HECMCFGC_00999	1.75e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HECMCFGC_01000	5.08e-299	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HECMCFGC_01001	5.19e-309	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HECMCFGC_01002	3.55e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HECMCFGC_01003	2.32e-261	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HECMCFGC_01004	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HECMCFGC_01005	3.86e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HECMCFGC_01006	0.0	corC	-	-	S	-	-	-	CBS domain
HECMCFGC_01007	1.33e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HECMCFGC_01008	3.27e-276	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HECMCFGC_01009	2.76e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HECMCFGC_01010	4.41e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HECMCFGC_01012	4.56e-211	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HECMCFGC_01013	1.6e-309	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HECMCFGC_01014	2.19e-142	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HECMCFGC_01015	8.33e-133	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HECMCFGC_01016	1.25e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HECMCFGC_01017	2.81e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HECMCFGC_01018	8.39e-299	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HECMCFGC_01019	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HECMCFGC_01020	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HECMCFGC_01021	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HECMCFGC_01022	7.3e-105	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HECMCFGC_01023	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HECMCFGC_01024	6.12e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HECMCFGC_01025	3.52e-91	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HECMCFGC_01026	1.21e-251	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HECMCFGC_01027	5e-98	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HECMCFGC_01028	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HECMCFGC_01029	6.59e-48	-	-	-	-	-	-	-	-
HECMCFGC_01030	1.28e-76	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HECMCFGC_01031	5.73e-165	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HECMCFGC_01032	7.89e-186	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HECMCFGC_01033	2.65e-102	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HECMCFGC_01034	3.3e-139	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
HECMCFGC_01035	1.18e-156	-	-	-	L	ko:K07485	-	ko00000	Transposase
HECMCFGC_01036	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HECMCFGC_01037	0.0	-	2.4.1.333	GH94	G	ko:K21298	-	ko00000,ko01000	Glycosyltransferase 36 associated
HECMCFGC_01038	5.31e-145	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HECMCFGC_01039	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HECMCFGC_01040	3.72e-176	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HECMCFGC_01041	1.77e-200	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01042	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HECMCFGC_01043	2.87e-153	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_01045	9.08e-86	-	-	-	L	-	-	-	PFAM Integrase catalytic
HECMCFGC_01046	8.88e-12	intA	-	-	L	-	-	-	Phage integrase family
HECMCFGC_01047	3.49e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF1048)
HECMCFGC_01048	1.78e-38	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HECMCFGC_01049	7.31e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HECMCFGC_01050	6.87e-82	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HECMCFGC_01052	5.24e-56	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HECMCFGC_01053	1.03e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HECMCFGC_01054	3.53e-66	-	-	-	S	-	-	-	SdpI/YhfL protein family
HECMCFGC_01055	1.65e-60	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
HECMCFGC_01056	1.2e-199	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HECMCFGC_01057	5.26e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HECMCFGC_01058	3.58e-181	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HECMCFGC_01059	9.39e-277	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HECMCFGC_01060	4.61e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
HECMCFGC_01061	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HECMCFGC_01062	1.48e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HECMCFGC_01063	3.65e-308	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HECMCFGC_01064	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HECMCFGC_01065	1.11e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HECMCFGC_01066	4.03e-200	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HECMCFGC_01067	4.34e-209	-	-	-	M	-	-	-	pfam nlp p60
HECMCFGC_01068	4.2e-145	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HECMCFGC_01069	7.75e-138	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HECMCFGC_01070	1.75e-261	-	-	-	-	-	-	-	-
HECMCFGC_01071	6.13e-52	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HECMCFGC_01072	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HECMCFGC_01073	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HECMCFGC_01074	4.94e-287	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HECMCFGC_01075	1.68e-228	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01076	1.38e-309	-	-	-	T	-	-	-	Histidine kinase
HECMCFGC_01077	3.4e-146	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HECMCFGC_01078	6.7e-148	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HECMCFGC_01079	1.25e-241	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HECMCFGC_01080	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HECMCFGC_01081	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HECMCFGC_01082	2.42e-298	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HECMCFGC_01083	1.72e-207	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HECMCFGC_01084	6.02e-135	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HECMCFGC_01085	8.24e-306	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HECMCFGC_01087	1.38e-82	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HECMCFGC_01088	5.33e-167	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HECMCFGC_01089	4.21e-19	-	-	-	T	-	-	-	Histidine kinase
HECMCFGC_01090	1.34e-260	-	-	-	T	-	-	-	Histidine kinase
HECMCFGC_01091	3.69e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HECMCFGC_01092	5.8e-16	-	-	-	-	-	-	-	-
HECMCFGC_01093	6.01e-93	-	-	-	-	-	-	-	-
HECMCFGC_01094	3.4e-199	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HECMCFGC_01095	1.85e-62	-	-	-	Q	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01096	7.46e-233	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HECMCFGC_01097	8.62e-53	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HECMCFGC_01098	2.55e-65	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HECMCFGC_01100	1.22e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HECMCFGC_01102	1.7e-121	-	-	-	-	-	-	-	-
HECMCFGC_01103	1.46e-166	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HECMCFGC_01104	4.53e-206	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HECMCFGC_01105	2.11e-94	-	-	-	-	-	-	-	-
HECMCFGC_01106	3.95e-82	-	-	-	-	-	-	-	-
HECMCFGC_01107	1.95e-191	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HECMCFGC_01108	5.85e-133	-	-	-	-	-	-	-	-
HECMCFGC_01109	7.38e-167	-	-	-	-	-	-	-	-
HECMCFGC_01110	3.17e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01112	9.24e-33	-	-	-	-	-	-	-	-
HECMCFGC_01113	8.62e-138	-	-	-	-	-	-	-	-
HECMCFGC_01114	4.77e-61	-	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HECMCFGC_01115	8.36e-67	hipA	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	kinase activity
HECMCFGC_01116	5.03e-43	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
HECMCFGC_01117	8.81e-148	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
HECMCFGC_01118	1.32e-108	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HECMCFGC_01120	2.12e-96	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECMCFGC_01121	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HECMCFGC_01122	5.32e-11	-	-	-	-	-	-	-	-
HECMCFGC_01123	5.5e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
HECMCFGC_01124	1.18e-98	-	-	-	-	-	-	-	-
HECMCFGC_01125	3.56e-212	-	-	-	-	-	-	-	-
HECMCFGC_01126	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HECMCFGC_01127	4.61e-93	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HECMCFGC_01128	1.68e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HECMCFGC_01129	2.09e-100	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HECMCFGC_01130	6.18e-283	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HECMCFGC_01131	6.76e-222	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HECMCFGC_01132	4.09e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HECMCFGC_01133	3.13e-170	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HECMCFGC_01134	1.6e-186	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HECMCFGC_01135	2.69e-192	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HECMCFGC_01136	1.96e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HECMCFGC_01137	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HECMCFGC_01138	5.83e-120	-	-	-	-	-	-	-	-
HECMCFGC_01139	1.25e-263	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HECMCFGC_01140	3.32e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HECMCFGC_01141	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HECMCFGC_01142	8.15e-149	-	-	-	M	-	-	-	Peptidase family M23
HECMCFGC_01144	5.28e-43	-	-	-	L	-	-	-	Phage integrase family
HECMCFGC_01145	7.76e-75	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA-like C-terminal domain
HECMCFGC_01146	2.49e-183	-	-	-	S	-	-	-	Fic/DOC family
HECMCFGC_01147	1.74e-91	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
HECMCFGC_01148	3.65e-251	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HECMCFGC_01149	2.43e-179	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HECMCFGC_01150	4.02e-182	-	-	-	-	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HECMCFGC_01151	2.21e-89	-	-	-	-	-	-	-	-
HECMCFGC_01153	9.59e-305	-	-	-	T	-	-	-	Histidine kinase
HECMCFGC_01154	5.21e-155	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HECMCFGC_01156	1.32e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HECMCFGC_01157	6.98e-137	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HECMCFGC_01158	8.41e-203	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HECMCFGC_01159	1.24e-111	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HECMCFGC_01160	8.37e-220	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HECMCFGC_01161	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HECMCFGC_01162	8.17e-84	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HECMCFGC_01163	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HECMCFGC_01164	2.62e-206	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HECMCFGC_01165	4.06e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HECMCFGC_01166	2.1e-215	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HECMCFGC_01167	1.72e-295	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HECMCFGC_01168	2.86e-93	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HECMCFGC_01169	3.5e-220	-	-	-	EG	-	-	-	EamA-like transporter family
HECMCFGC_01170	5.06e-169	-	-	-	C	-	-	-	Putative TM nitroreductase
HECMCFGC_01171	4.34e-42	-	-	-	-	-	-	-	-
HECMCFGC_01172	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HECMCFGC_01173	1.16e-305	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HECMCFGC_01174	5.37e-266	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_01175	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HECMCFGC_01176	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HECMCFGC_01177	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HECMCFGC_01178	3.57e-200	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01179	2.78e-222	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01180	1.01e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01181	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HECMCFGC_01182	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HECMCFGC_01183	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HECMCFGC_01184	4.78e-110	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HECMCFGC_01185	1.14e-60	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
HECMCFGC_01186	1.11e-216	-	-	-	S	-	-	-	Fic/DOC family
HECMCFGC_01187	0.0	-	-	-	S	-	-	-	HipA-like C-terminal domain
HECMCFGC_01189	1.31e-98	-	-	-	-	-	-	-	-
HECMCFGC_01190	8.07e-133	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HECMCFGC_01191	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HECMCFGC_01192	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HECMCFGC_01193	4.95e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HECMCFGC_01194	1.18e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HECMCFGC_01195	3.47e-297	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HECMCFGC_01196	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HECMCFGC_01198	8.31e-135	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01199	1.15e-27	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HECMCFGC_01202	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HECMCFGC_01203	4.28e-219	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HECMCFGC_01204	1.78e-284	-	-	-	G	-	-	-	Major Facilitator Superfamily
HECMCFGC_01205	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HECMCFGC_01206	4.78e-246	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HECMCFGC_01207	4.85e-146	-	-	-	-	-	-	-	-
HECMCFGC_01208	4.11e-252	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HECMCFGC_01209	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HECMCFGC_01210	1.01e-165	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HECMCFGC_01211	4.82e-153	-	-	-	-	-	-	-	-
HECMCFGC_01212	1.26e-243	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HECMCFGC_01213	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HECMCFGC_01214	1.24e-154	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HECMCFGC_01215	4.52e-133	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HECMCFGC_01216	1.25e-263	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HECMCFGC_01217	9.29e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HECMCFGC_01218	2.3e-101	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECMCFGC_01219	4.76e-119	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HECMCFGC_01220	3.47e-151	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HECMCFGC_01221	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HECMCFGC_01222	2.74e-193	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HECMCFGC_01223	1.5e-229	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HECMCFGC_01224	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HECMCFGC_01225	2.71e-190	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HECMCFGC_01226	8.8e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HECMCFGC_01227	1.4e-175	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HECMCFGC_01228	5.23e-146	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HECMCFGC_01229	2.33e-155	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HECMCFGC_01230	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HECMCFGC_01231	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HECMCFGC_01232	2.73e-127	-	-	-	-	-	-	-	-
HECMCFGC_01233	7.26e-304	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HECMCFGC_01234	4.96e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HECMCFGC_01235	2.06e-197	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HECMCFGC_01236	1.13e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HECMCFGC_01237	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HECMCFGC_01238	2.81e-233	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HECMCFGC_01239	1.39e-204	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01240	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HECMCFGC_01241	5.98e-242	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HECMCFGC_01242	1.23e-188	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_01243	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HECMCFGC_01244	2.36e-56	-	-	-	-	-	-	-	-
HECMCFGC_01245	3.34e-243	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HECMCFGC_01246	1.41e-241	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HECMCFGC_01247	4.03e-101	-	-	-	-	-	-	-	-
HECMCFGC_01248	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HECMCFGC_01249	5.96e-139	-	-	-	K	-	-	-	Virulence activator alpha C-term
HECMCFGC_01250	5.21e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01251	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HECMCFGC_01252	3.49e-24	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HECMCFGC_01253	9.54e-302	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HECMCFGC_01254	7.53e-208	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HECMCFGC_01255	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HECMCFGC_01256	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HECMCFGC_01257	3.89e-205	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HECMCFGC_01258	2.87e-146	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HECMCFGC_01259	1.1e-193	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HECMCFGC_01260	4.16e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HECMCFGC_01261	9.55e-200	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HECMCFGC_01262	3.32e-248	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HECMCFGC_01263	1.25e-204	-	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HECMCFGC_01264	9.5e-115	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HECMCFGC_01265	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HECMCFGC_01266	2.72e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HECMCFGC_01267	1.72e-157	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HECMCFGC_01268	4.29e-08	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
HECMCFGC_01269	5.45e-173	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HECMCFGC_01270	5.83e-251	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HECMCFGC_01271	4.92e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HECMCFGC_01272	2.06e-233	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HECMCFGC_01273	8.5e-245	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HECMCFGC_01274	2.24e-238	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HECMCFGC_01275	2.29e-68	-	-	-	-	-	-	-	-
HECMCFGC_01276	1.29e-175	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HECMCFGC_01277	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HECMCFGC_01278	1.66e-246	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HECMCFGC_01279	1.52e-63	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HECMCFGC_01280	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HECMCFGC_01281	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HECMCFGC_01282	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HECMCFGC_01283	4.18e-123	-	-	-	F	-	-	-	NUDIX domain
HECMCFGC_01284	1.18e-312	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HECMCFGC_01285	1.15e-193	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HECMCFGC_01286	4.56e-266	-	-	-	GK	-	-	-	ROK family
HECMCFGC_01287	2e-211	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HECMCFGC_01288	3.22e-288	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HECMCFGC_01289	1.94e-215	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HECMCFGC_01290	4.46e-126	-	-	-	G	-	-	-	Major Facilitator Superfamily
HECMCFGC_01291	2.03e-111	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HECMCFGC_01292	7.68e-59	-	-	-	-	-	-	-	-
HECMCFGC_01295	6.82e-230	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HECMCFGC_01296	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HECMCFGC_01297	1.02e-277	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HECMCFGC_01298	2.45e-288	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HECMCFGC_01299	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HECMCFGC_01300	3.33e-265	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HECMCFGC_01301	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HECMCFGC_01302	2.6e-200	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HECMCFGC_01303	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HECMCFGC_01304	1.29e-90	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HECMCFGC_01305	2.09e-243	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HECMCFGC_01306	2.33e-120	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HECMCFGC_01307	0.0	-	-	-	L	-	-	-	DNA helicase
HECMCFGC_01308	4.79e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HECMCFGC_01309	4.08e-101	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HECMCFGC_01310	2.04e-67	-	-	-	M	-	-	-	Lysin motif
HECMCFGC_01311	4.82e-165	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HECMCFGC_01312	1.09e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HECMCFGC_01313	1.61e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HECMCFGC_01314	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HECMCFGC_01315	1.99e-159	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HECMCFGC_01316	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HECMCFGC_01317	3.05e-280	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HECMCFGC_01318	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HECMCFGC_01319	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
HECMCFGC_01320	4.12e-168	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HECMCFGC_01321	8.43e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HECMCFGC_01322	7.57e-163	-	-	-	-	-	-	-	-
HECMCFGC_01323	4.75e-144	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HECMCFGC_01324	1.91e-280	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HECMCFGC_01325	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HECMCFGC_01326	9.87e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
HECMCFGC_01327	3.87e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
HECMCFGC_01328	7.41e-153	-	-	-	-	-	-	-	-
HECMCFGC_01330	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HECMCFGC_01331	7.93e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HECMCFGC_01333	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HECMCFGC_01334	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HECMCFGC_01335	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HECMCFGC_01336	1.33e-273	-	-	-	-	-	-	-	-
HECMCFGC_01338	3.67e-136	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HECMCFGC_01340	5.09e-161	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HECMCFGC_01341	1.43e-115	-	-	-	K	-	-	-	Putative zinc ribbon domain
HECMCFGC_01342	9.31e-36	zntR	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HECMCFGC_01343	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HECMCFGC_01344	6.09e-105	-	-	-	L	-	-	-	NUDIX domain
HECMCFGC_01345	1.19e-38	-	-	-	L	-	-	-	NUDIX domain
HECMCFGC_01346	7.7e-226	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HECMCFGC_01347	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HECMCFGC_01348	2.41e-166	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HECMCFGC_01350	2.64e-141	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HECMCFGC_01351	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HECMCFGC_01352	2.57e-226	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HECMCFGC_01353	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HECMCFGC_01354	1.5e-137	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HECMCFGC_01355	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HECMCFGC_01356	8.83e-209	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HECMCFGC_01357	3.81e-257	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HECMCFGC_01358	1.75e-204	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01359	2.59e-173	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HECMCFGC_01360	2.52e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HECMCFGC_01361	2.16e-130	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HECMCFGC_01362	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HECMCFGC_01363	4.99e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HECMCFGC_01364	8.25e-249	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HECMCFGC_01365	9.76e-145	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HECMCFGC_01366	7.18e-191	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HECMCFGC_01367	6.1e-101	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HECMCFGC_01368	0.0	-	-	-	-	-	-	-	-
HECMCFGC_01369	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HECMCFGC_01370	2.06e-74	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HECMCFGC_01371	9.27e-306	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HECMCFGC_01372	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HECMCFGC_01373	8.13e-62	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HECMCFGC_01374	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HECMCFGC_01375	3.2e-197	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HECMCFGC_01376	7.1e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HECMCFGC_01377	8.17e-98	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HECMCFGC_01378	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HECMCFGC_01379	8.17e-122	-	-	-	-	-	-	-	-
HECMCFGC_01381	3.69e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HECMCFGC_01382	1.13e-132	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HECMCFGC_01383	1.89e-113	-	-	-	D	-	-	-	Septum formation initiator
HECMCFGC_01384	2.49e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HECMCFGC_01385	1.28e-227	-	-	-	C	-	-	-	Aldo/keto reductase family
HECMCFGC_01386	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HECMCFGC_01387	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HECMCFGC_01388	1.11e-119	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HECMCFGC_01389	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HECMCFGC_01390	2.97e-20	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HECMCFGC_01391	3.16e-117	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HECMCFGC_01392	1.1e-177	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HECMCFGC_01393	2.19e-125	-	-	-	-	-	-	-	-
HECMCFGC_01394	1.75e-295	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HECMCFGC_01395	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HECMCFGC_01396	4.46e-52	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HECMCFGC_01397	3.98e-91	-	-	-	S	-	-	-	ABC-2 family transporter protein
HECMCFGC_01398	1.94e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
HECMCFGC_01399	6.07e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01400	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HECMCFGC_01401	1.06e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HECMCFGC_01402	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HECMCFGC_01403	4.51e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HECMCFGC_01405	5.12e-54	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HECMCFGC_01406	1.85e-25	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HECMCFGC_01407	3.81e-151	-	-	-	-	-	-	-	-
HECMCFGC_01408	1.49e-178	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HECMCFGC_01410	1.39e-256	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HECMCFGC_01411	3.01e-293	-	-	-	L	-	-	-	Tetratricopeptide repeat
HECMCFGC_01412	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HECMCFGC_01413	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HECMCFGC_01414	1.1e-179	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HECMCFGC_01415	3.85e-130	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HECMCFGC_01416	6.15e-83	-	-	-	P	-	-	-	Rhodanese Homology Domain
HECMCFGC_01417	5.9e-191	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HECMCFGC_01418	5.07e-202	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HECMCFGC_01419	3.55e-39	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HECMCFGC_01420	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HECMCFGC_01421	1.2e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HECMCFGC_01422	2.51e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HECMCFGC_01423	8.39e-233	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HECMCFGC_01424	8.03e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HECMCFGC_01425	3.39e-226	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HECMCFGC_01426	6.52e-270	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HECMCFGC_01427	6.39e-257	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HECMCFGC_01428	5.15e-119	-	-	-	-	-	-	-	-
HECMCFGC_01429	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HECMCFGC_01430	4.35e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HECMCFGC_01431	2.43e-206	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HECMCFGC_01432	5.9e-208	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HECMCFGC_01433	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01434	2.53e-139	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HECMCFGC_01435	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HECMCFGC_01436	4.43e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HECMCFGC_01437	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HECMCFGC_01438	5.87e-182	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HECMCFGC_01439	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HECMCFGC_01440	1.42e-52	-	-	-	-	-	-	-	-
HECMCFGC_01442	1.24e-264	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HECMCFGC_01443	6.28e-48	-	-	-	S	-	-	-	Type II restriction endonuclease EcoO109I
HECMCFGC_01444	6.18e-159	-	-	-	-	-	-	-	-
HECMCFGC_01445	2.16e-71	hsdM3	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	PFAM N-6 DNA methylase
HECMCFGC_01446	2.81e-122	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HECMCFGC_01447	1.01e-47	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HECMCFGC_01448	2.22e-194	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HECMCFGC_01449	1.46e-47	-	-	-	-	-	-	-	-
HECMCFGC_01450	9.84e-178	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HECMCFGC_01451	2.41e-101	crgA	-	-	D	-	-	-	Involved in cell division
HECMCFGC_01452	1.56e-162	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HECMCFGC_01453	1.54e-289	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HECMCFGC_01454	1.11e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HECMCFGC_01455	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HECMCFGC_01456	1.54e-221	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HECMCFGC_01457	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HECMCFGC_01458	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HECMCFGC_01459	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HECMCFGC_01460	1.09e-105	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HECMCFGC_01461	3.54e-165	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HECMCFGC_01462	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HECMCFGC_01463	9.24e-272	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HECMCFGC_01464	2.86e-118	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
HECMCFGC_01465	2.68e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HECMCFGC_01466	7.42e-28	-	-	-	-	-	-	-	-
HECMCFGC_01467	0.0	-	-	-	S	-	-	-	Putative esterase
HECMCFGC_01468	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HECMCFGC_01469	2.58e-256	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HECMCFGC_01470	4.3e-170	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HECMCFGC_01471	3.8e-252	-	-	-	S	-	-	-	Fic/DOC family
HECMCFGC_01472	2.95e-135	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HECMCFGC_01473	4.44e-41	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HECMCFGC_01474	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
HECMCFGC_01475	6.69e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HECMCFGC_01476	1.01e-68	-	-	-	S	-	-	-	Putative heavy-metal-binding
HECMCFGC_01477	2.37e-189	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HECMCFGC_01479	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HECMCFGC_01480	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HECMCFGC_01481	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HECMCFGC_01482	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HECMCFGC_01483	6.77e-219	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HECMCFGC_01485	1.81e-222	-	-	-	EG	-	-	-	EamA-like transporter family
HECMCFGC_01486	2.3e-254	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HECMCFGC_01487	6.8e-309	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HECMCFGC_01488	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HECMCFGC_01489	9.95e-201	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HECMCFGC_01490	3.12e-82	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HECMCFGC_01491	1.02e-63	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HECMCFGC_01492	1.09e-46	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_01493	3.59e-169	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_01494	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HECMCFGC_01495	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HECMCFGC_01496	8.14e-241	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_01497	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HECMCFGC_01498	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HECMCFGC_01499	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HECMCFGC_01500	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HECMCFGC_01501	7.5e-238	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HECMCFGC_01502	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
HECMCFGC_01503	0.0	-	-	-	M	-	-	-	domain protein
HECMCFGC_01504	1.71e-195	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HECMCFGC_01505	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HECMCFGC_01506	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HECMCFGC_01507	6.91e-299	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01508	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01509	1.29e-206	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01510	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HECMCFGC_01511	5.68e-122	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
HECMCFGC_01512	1.71e-173	traX	-	-	S	-	-	-	TraX protein
HECMCFGC_01513	1.6e-247	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HECMCFGC_01514	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
HECMCFGC_01515	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HECMCFGC_01516	2.49e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HECMCFGC_01517	2.45e-224	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HECMCFGC_01518	2.35e-133	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HECMCFGC_01519	1.48e-128	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
HECMCFGC_01520	7.9e-182	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HECMCFGC_01521	2.23e-163	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HECMCFGC_01522	1.82e-171	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HECMCFGC_01523	1.76e-157	-	-	-	D	-	-	-	bacterial-type flagellum organization
HECMCFGC_01524	1.47e-242	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HECMCFGC_01525	2.81e-92	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HECMCFGC_01526	3.27e-149	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
HECMCFGC_01527	3.68e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HECMCFGC_01528	9.46e-77	-	-	-	U	-	-	-	TadE-like protein
HECMCFGC_01529	3.01e-70	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HECMCFGC_01530	5.41e-275	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
HECMCFGC_01531	1.62e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_01532	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HECMCFGC_01533	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HECMCFGC_01534	2.07e-163	-	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HECMCFGC_01535	1.66e-271	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HECMCFGC_01536	2.05e-86	-	-	-	V	-	-	-	Abi-like protein
HECMCFGC_01537	1.79e-243	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HECMCFGC_01538	6.3e-174	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HECMCFGC_01539	6.76e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HECMCFGC_01540	3.76e-269	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HECMCFGC_01541	1.64e-143	-	-	-	-	-	-	-	-
HECMCFGC_01542	6.78e-218	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
HECMCFGC_01544	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HECMCFGC_01545	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HECMCFGC_01546	5.86e-189	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01547	1.66e-214	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01548	0.0	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01549	2.53e-296	-	-	-	G	-	-	-	Protein of unknown function (DUF2961)
HECMCFGC_01550	7.93e-306	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01551	1.36e-244	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_01552	2e-240	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HECMCFGC_01553	7.15e-197	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01554	1.9e-208	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01555	9.35e-312	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01556	1.55e-294	-	-	-	GK	-	-	-	ROK family
HECMCFGC_01557	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HECMCFGC_01558	4.34e-103	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HECMCFGC_01559	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HECMCFGC_01560	1.77e-159	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HECMCFGC_01561	1.02e-187	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HECMCFGC_01562	3.67e-195	-	-	-	-	-	-	-	-
HECMCFGC_01563	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HECMCFGC_01564	7.05e-134	-	-	-	-	-	-	-	-
HECMCFGC_01565	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HECMCFGC_01566	4.38e-161	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HECMCFGC_01567	4.61e-27	-	-	-	-	-	-	-	-
HECMCFGC_01568	1.07e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF4091)
HECMCFGC_01569	3.08e-220	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HECMCFGC_01570	5.37e-216	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HECMCFGC_01571	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HECMCFGC_01572	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HECMCFGC_01573	4.31e-197	-	-	-	-	-	-	-	-
HECMCFGC_01574	2.77e-18	tnp3521a2	-	-	L	-	-	-	Integrase core domain
HECMCFGC_01575	7.94e-167	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECMCFGC_01576	1.98e-186	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HECMCFGC_01577	5.52e-223	rbsA	3.6.3.17	-	G	ko:K10441,ko:K10542,ko:K17215	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01578	6.14e-191	-	-	-	U	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HECMCFGC_01579	3.33e-232	-	-	-	-	-	-	-	-
HECMCFGC_01580	7.1e-138	-	-	-	L	-	-	-	Winged helix-turn helix
HECMCFGC_01581	7.18e-31	-	-	-	L	-	-	-	Winged helix-turn helix
HECMCFGC_01582	7.62e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HECMCFGC_01583	1.02e-175	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
HECMCFGC_01584	1.55e-307	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HECMCFGC_01585	3.61e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECMCFGC_01586	3.21e-93	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HECMCFGC_01587	2.04e-275	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HECMCFGC_01588	1.26e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HECMCFGC_01590	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HECMCFGC_01591	8.2e-113	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HECMCFGC_01592	1.62e-57	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HECMCFGC_01594	6.17e-158	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HECMCFGC_01595	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HECMCFGC_01596	3.18e-155	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECMCFGC_01597	2.5e-162	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HECMCFGC_01598	5.67e-16	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HECMCFGC_01599	1.36e-79	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HECMCFGC_01600	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HECMCFGC_01601	1.31e-165	-	-	-	T	-	-	-	GHKL domain
HECMCFGC_01602	4.57e-152	-	-	-	T	-	-	-	LytTr DNA-binding domain
HECMCFGC_01603	1.36e-90	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HECMCFGC_01604	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HECMCFGC_01605	1.79e-181	-	-	-	O	-	-	-	Thioredoxin
HECMCFGC_01607	7e-281	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HECMCFGC_01608	7.89e-216	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HECMCFGC_01609	1.43e-221	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HECMCFGC_01610	4.16e-143	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HECMCFGC_01611	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HECMCFGC_01612	6.71e-214	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HECMCFGC_01613	0.0	-	-	-	-	-	-	-	-
HECMCFGC_01614	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HECMCFGC_01615	7.34e-227	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HECMCFGC_01616	2.35e-285	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HECMCFGC_01617	2.99e-222	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HECMCFGC_01618	2.06e-158	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HECMCFGC_01619	3.27e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HECMCFGC_01620	1.33e-34	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HECMCFGC_01621	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HECMCFGC_01622	7.74e-17	-	-	-	-	-	-	-	-
HECMCFGC_01623	8.2e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECMCFGC_01624	3.8e-276	-	-	-	G	-	-	-	Transmembrane secretion effector
HECMCFGC_01625	1.76e-23	-	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
HECMCFGC_01626	7.31e-308	-	-	-	S	-	-	-	HipA-like C-terminal domain
HECMCFGC_01627	5.09e-51	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HECMCFGC_01628	5.72e-69	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HECMCFGC_01629	1.67e-110	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HECMCFGC_01630	6.44e-205	-	-	-	J	-	-	-	Methyltransferase domain
HECMCFGC_01631	1.11e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
HECMCFGC_01632	7.8e-300	-	-	-	K	-	-	-	Fic/DOC family
HECMCFGC_01633	0.0	-	-	-	L	-	-	-	ABC transporter
HECMCFGC_01634	6.11e-216	-	-	-	V	-	-	-	MatE
HECMCFGC_01635	2.66e-54	-	-	-	V	-	-	-	MatE
HECMCFGC_01637	1.22e-75	tetD	-	-	K	ko:K13653	-	ko00000,ko03000	Arac family
HECMCFGC_01638	1.13e-116	tetD	-	-	K	ko:K13653	-	ko00000,ko03000	Arac family
HECMCFGC_01639	9.63e-260	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HECMCFGC_01640	1.95e-142	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01641	1.07e-151	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01642	7.78e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
HECMCFGC_01643	1.77e-199	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HECMCFGC_01644	6.61e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HECMCFGC_01645	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HECMCFGC_01646	0.0	-	-	-	T	-	-	-	Histidine kinase
HECMCFGC_01647	7.1e-181	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HECMCFGC_01648	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HECMCFGC_01649	2.24e-210	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECMCFGC_01650	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HECMCFGC_01651	2.26e-210	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HECMCFGC_01652	2.37e-27	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HECMCFGC_01653	8.76e-99	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HECMCFGC_01654	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HECMCFGC_01655	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HECMCFGC_01656	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HECMCFGC_01657	6.63e-232	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HECMCFGC_01658	1.13e-146	safC	-	-	S	-	-	-	O-methyltransferase
HECMCFGC_01659	6.5e-215	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HECMCFGC_01660	1.23e-310	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HECMCFGC_01661	6.43e-307	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HECMCFGC_01664	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HECMCFGC_01665	1.28e-155	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HECMCFGC_01666	2.96e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HECMCFGC_01667	7.52e-78	-	-	-	-	-	-	-	-
HECMCFGC_01668	4.32e-313	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HECMCFGC_01669	3.47e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HECMCFGC_01670	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HECMCFGC_01671	6.98e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
HECMCFGC_01672	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HECMCFGC_01673	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HECMCFGC_01674	6.14e-52	-	-	-	-	-	-	-	-
HECMCFGC_01675	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HECMCFGC_01676	5.66e-285	-	-	-	S	-	-	-	Peptidase dimerisation domain
HECMCFGC_01677	1.59e-145	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01678	2.82e-280	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HECMCFGC_01679	3.5e-223	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HECMCFGC_01680	3.85e-199	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HECMCFGC_01683	7.2e-174	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HECMCFGC_01684	5.45e-86	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HECMCFGC_01685	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HECMCFGC_01686	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HECMCFGC_01687	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HECMCFGC_01688	3.35e-47	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HECMCFGC_01690	1.12e-83	-	-	-	-	-	-	-	-
HECMCFGC_01691	1.68e-156	-	-	-	O	-	-	-	AAA domain (Cdc48 subfamily)
HECMCFGC_01694	4.25e-65	-	-	-	-	-	-	-	-
HECMCFGC_01695	3.21e-10	-	-	-	-	-	-	-	-
HECMCFGC_01696	2.72e-42	-	-	-	-	-	-	-	-
HECMCFGC_01697	4.28e-176	-	-	-	L	-	-	-	IstB-like ATP binding protein
HECMCFGC_01698	1.08e-192	-	-	-	L	-	-	-	PFAM Integrase catalytic
HECMCFGC_01699	2.16e-238	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HECMCFGC_01700	2.07e-73	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HECMCFGC_01701	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HECMCFGC_01702	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HECMCFGC_01703	5.94e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HECMCFGC_01704	2.26e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HECMCFGC_01705	3.41e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HECMCFGC_01706	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HECMCFGC_01707	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HECMCFGC_01708	6.05e-89	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HECMCFGC_01709	1.76e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HECMCFGC_01710	9.71e-13	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HECMCFGC_01711	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HECMCFGC_01712	1.19e-259	-	-	-	V	-	-	-	VanZ like family
HECMCFGC_01713	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HECMCFGC_01714	1.22e-250	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HECMCFGC_01717	3.89e-30	-	-	-	L	ko:K07485	-	ko00000	Transposase
HECMCFGC_01718	2.19e-74	-	-	-	F	-	-	-	Calcineurin-like phosphoesterase
HECMCFGC_01719	5.8e-105	ptxC	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01720	7.25e-101	-	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01721	1.97e-103	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HECMCFGC_01722	2.87e-145	-	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HECMCFGC_01723	1.12e-24	-	-	-	K	-	-	-	Transcriptional regulator, rpir family
HECMCFGC_01724	3.55e-23	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HECMCFGC_01725	1.24e-256	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HECMCFGC_01726	4.5e-188	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HECMCFGC_01727	6.04e-82	gntK	2.7.1.12, 2.7.1.71	-	F	ko:K00851,ko:K00891	ko00030,ko00400,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate kinase
HECMCFGC_01728	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HECMCFGC_01729	1.09e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HECMCFGC_01730	6.91e-298	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HECMCFGC_01731	2.17e-266	-	-	-	S	-	-	-	AAA ATPase domain
HECMCFGC_01732	3.52e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HECMCFGC_01733	6.83e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HECMCFGC_01734	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HECMCFGC_01735	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
HECMCFGC_01736	1.69e-203	-	-	-	-	-	-	-	-
HECMCFGC_01737	2.38e-125	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HECMCFGC_01738	3.73e-269	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HECMCFGC_01739	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
HECMCFGC_01740	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
HECMCFGC_01741	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
HECMCFGC_01742	1.93e-203	-	-	-	P	-	-	-	VTC domain
HECMCFGC_01743	2.97e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
HECMCFGC_01744	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
HECMCFGC_01745	3.39e-157	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HECMCFGC_01746	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HECMCFGC_01747	5.6e-45	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HECMCFGC_01748	1.46e-50	-	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HECMCFGC_01749	4.83e-15	-	-	-	-	-	-	-	-
HECMCFGC_01750	1.86e-140	-	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HECMCFGC_01752	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HECMCFGC_01753	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HECMCFGC_01754	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HECMCFGC_01755	3.78e-224	-	-	-	S	-	-	-	Protein conserved in bacteria
HECMCFGC_01756	0.0	-	-	-	S	-	-	-	Amidohydrolase family
HECMCFGC_01757	5.93e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HECMCFGC_01758	2.95e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HECMCFGC_01759	1.87e-146	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HECMCFGC_01760	8.8e-264	-	-	-	T	-	-	-	Histidine kinase
HECMCFGC_01761	7.02e-294	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECMCFGC_01762	2.13e-94	-	-	-	I	-	-	-	Sterol carrier protein
HECMCFGC_01764	5.16e-15	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HECMCFGC_01765	3.21e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_01766	7.44e-207	-	-	-	P	-	-	-	Phosphate transporter family
HECMCFGC_01767	1.75e-205	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01768	1.32e-182	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01769	2.45e-304	-	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01770	2.56e-216	-	-	-	C	-	-	-	Domain of unknown function
HECMCFGC_01771	1.03e-141	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HECMCFGC_01772	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HECMCFGC_01773	3.48e-245	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HECMCFGC_01774	2.34e-21	-	-	-	K	-	-	-	MerR family regulatory protein
HECMCFGC_01775	2.43e-23	-	-	-	K	-	-	-	MerR family regulatory protein
HECMCFGC_01776	3.37e-111	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HECMCFGC_01777	3.93e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HECMCFGC_01778	2.94e-89	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HECMCFGC_01779	1.24e-237	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HECMCFGC_01780	9e-187	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HECMCFGC_01781	8.57e-164	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HECMCFGC_01782	4.1e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HECMCFGC_01783	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HECMCFGC_01784	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HECMCFGC_01785	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HECMCFGC_01786	3.25e-142	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
HECMCFGC_01788	3.93e-248	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HECMCFGC_01789	4.49e-279	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HECMCFGC_01790	1.22e-289	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HECMCFGC_01791	2.71e-297	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HECMCFGC_01792	4.83e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HECMCFGC_01793	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HECMCFGC_01794	1.45e-296	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HECMCFGC_01795	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HECMCFGC_01796	4.82e-147	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HECMCFGC_01797	8.33e-187	-	-	-	-	-	-	-	-
HECMCFGC_01801	2.56e-130	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HECMCFGC_01802	1.6e-18	-	-	-	C	-	-	-	Aldo/keto reductase family
HECMCFGC_01803	3.3e-43	-	-	-	-	-	-	-	-
HECMCFGC_01804	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HECMCFGC_01805	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HECMCFGC_01806	5.52e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HECMCFGC_01807	3.49e-308	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HECMCFGC_01808	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
HECMCFGC_01809	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HECMCFGC_01810	4.01e-208	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HECMCFGC_01811	3.75e-126	-	-	-	S	-	-	-	cobalamin synthesis protein
HECMCFGC_01812	8.31e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HECMCFGC_01813	5.79e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HECMCFGC_01814	3.04e-59	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HECMCFGC_01815	4.94e-45	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HECMCFGC_01816	8.76e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HECMCFGC_01817	6.34e-27	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
HECMCFGC_01818	2.53e-35	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HECMCFGC_01819	1.27e-07	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HECMCFGC_01820	2.67e-238	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HECMCFGC_01821	7.72e-178	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
HECMCFGC_01822	1.62e-26	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
HECMCFGC_01823	6.13e-43	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
HECMCFGC_01824	9.84e-85	-	-	-	-	-	-	-	-
HECMCFGC_01825	1.05e-91	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HECMCFGC_01826	1.29e-33	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HECMCFGC_01827	6.17e-97	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HECMCFGC_01828	7.7e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HECMCFGC_01829	4.92e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HECMCFGC_01830	1.46e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HECMCFGC_01831	1.89e-229	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
HECMCFGC_01832	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HECMCFGC_01833	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HECMCFGC_01834	9.42e-258	-	-	-	M	-	-	-	Conserved repeat domain
HECMCFGC_01835	9.32e-184	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01836	6.28e-111	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	peptide-methionine (S)-S-oxide reductase activity
HECMCFGC_01837	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HECMCFGC_01838	8.46e-20	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HECMCFGC_01839	5.2e-282	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HECMCFGC_01840	7.73e-127	-	-	-	L	-	-	-	PFAM Integrase catalytic
HECMCFGC_01841	5.22e-35	-	-	-	S	-	-	-	AIPR protein
HECMCFGC_01842	1.14e-188	-	-	-	K	-	-	-	LysR substrate binding domain
HECMCFGC_01843	5.6e-130	-	-	-	K	-	-	-	LysR substrate binding domain
HECMCFGC_01844	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HECMCFGC_01845	1.97e-311	-	-	-	V	-	-	-	MatE
HECMCFGC_01846	3.8e-160	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
HECMCFGC_01847	0.000108	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HECMCFGC_01848	3.5e-149	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HECMCFGC_01849	1.18e-53	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HECMCFGC_01850	1.62e-234	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HECMCFGC_01851	1.66e-46	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HECMCFGC_01852	0.0	-	-	-	M	-	-	-	probably involved in cell wall
HECMCFGC_01853	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
HECMCFGC_01854	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HECMCFGC_01855	1.42e-174	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HECMCFGC_01856	5e-162	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01857	6.57e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HECMCFGC_01858	1.69e-119	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HECMCFGC_01859	2.95e-306	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HECMCFGC_01860	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HECMCFGC_01861	1.08e-216	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HECMCFGC_01862	1.12e-136	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HECMCFGC_01863	7.2e-175	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HECMCFGC_01865	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HECMCFGC_01866	1.26e-158	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HECMCFGC_01867	5.02e-295	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HECMCFGC_01868	1.32e-56	-	-	-	O	-	-	-	Glutaredoxin
HECMCFGC_01869	1.46e-270	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HECMCFGC_01870	1.03e-169	hflK	-	-	O	-	-	-	prohibitin homologues
HECMCFGC_01871	2.34e-203	-	-	-	S	-	-	-	Patatin-like phospholipase
HECMCFGC_01872	5.69e-191	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HECMCFGC_01873	3.24e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HECMCFGC_01874	9.32e-164	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HECMCFGC_01875	4.94e-213	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HECMCFGC_01876	3.25e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HECMCFGC_01877	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HECMCFGC_01878	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HECMCFGC_01879	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HECMCFGC_01880	1e-208	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HECMCFGC_01881	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HECMCFGC_01883	1.25e-278	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HECMCFGC_01884	2.51e-281	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HECMCFGC_01885	6.58e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HECMCFGC_01886	0.0	-	-	-	I	-	-	-	acetylesterase activity
HECMCFGC_01887	6.84e-166	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HECMCFGC_01888	1.58e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HECMCFGC_01889	8.22e-172	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01890	1.25e-242	-	-	-	P	-	-	-	NMT1/THI5 like
HECMCFGC_01891	1.16e-285	-	-	-	E	-	-	-	Aminotransferase class I and II
HECMCFGC_01892	1.13e-181	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01893	8.79e-09	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HECMCFGC_01894	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HECMCFGC_01895	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HECMCFGC_01896	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HECMCFGC_01897	2.24e-261	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HECMCFGC_01898	2.27e-146	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HECMCFGC_01899	9.16e-240	-	-	-	K	-	-	-	Periplasmic binding protein domain
HECMCFGC_01900	2.42e-178	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HECMCFGC_01901	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HECMCFGC_01902	3.69e-193	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01903	3.78e-223	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01904	2.64e-216	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HECMCFGC_01905	9.89e-198	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HECMCFGC_01906	9.36e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HECMCFGC_01907	3.17e-206	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HECMCFGC_01908	1.9e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HECMCFGC_01909	7.91e-270	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HECMCFGC_01910	1.03e-262	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HECMCFGC_01911	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HECMCFGC_01912	2.62e-159	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HECMCFGC_01913	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HECMCFGC_01914	4.75e-29	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HECMCFGC_01915	5.35e-30	-	-	-	K	-	-	-	AraC-like ligand binding domain
HECMCFGC_01916	9.34e-163	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HECMCFGC_01917	7.43e-149	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01918	2.14e-138	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01919	1.19e-131	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01920	2.46e-39	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HECMCFGC_01921	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HECMCFGC_01922	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HECMCFGC_01923	1.69e-207	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HECMCFGC_01924	5.6e-171	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HECMCFGC_01925	5.5e-300	-	-	-	G	-	-	-	Major Facilitator Superfamily
HECMCFGC_01926	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HECMCFGC_01927	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HECMCFGC_01928	2.93e-282	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HECMCFGC_01929	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HECMCFGC_01930	4.4e-306	-	-	-	S	-	-	-	Protein of unknown function DUF58
HECMCFGC_01931	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HECMCFGC_01932	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HECMCFGC_01933	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HECMCFGC_01934	3.82e-166	-	-	-	-	-	-	-	-
HECMCFGC_01935	1.77e-238	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HECMCFGC_01936	3.37e-148	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HECMCFGC_01937	2.02e-287	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_01938	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01942	1.58e-205	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HECMCFGC_01943	4.89e-50	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HECMCFGC_01944	2.81e-40	-	-	-	-	-	-	-	-
HECMCFGC_01945	1.36e-267	-	-	-	P	-	-	-	Citrate transporter
HECMCFGC_01946	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
HECMCFGC_01947	6.92e-148	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HECMCFGC_01948	1.63e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HECMCFGC_01949	1.15e-47	-	-	-	-	-	-	-	-
HECMCFGC_01950	2.05e-89	-	-	-	S	-	-	-	PIN domain
HECMCFGC_01951	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HECMCFGC_01952	3.97e-308	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HECMCFGC_01953	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HECMCFGC_01954	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HECMCFGC_01955	1.24e-89	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HECMCFGC_01956	1.43e-89	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HECMCFGC_01957	6.32e-61	-	-	-	FG	-	-	-	bis(5'-adenosyl)-triphosphatase activity
HECMCFGC_01958	4.85e-225	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Glucuronate isomerase
HECMCFGC_01959	7.25e-243	mtlD	1.1.1.57, 1.1.1.58	-	G	ko:K00040,ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
HECMCFGC_01960	7.87e-296	-	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mandelate racemase muconate lactonizing
HECMCFGC_01961	1.48e-83	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
HECMCFGC_01962	1.7e-293	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HECMCFGC_01963	3.03e-205	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
HECMCFGC_01964	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
HECMCFGC_01965	8.25e-44	-	-	-	-	-	-	-	-
HECMCFGC_01966	5.31e-167	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01967	1.02e-170	-	-	-	U	ko:K02025,ko:K17242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01968	2.39e-201	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01969	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
HECMCFGC_01970	8.01e-305	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
HECMCFGC_01971	8.95e-224	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HECMCFGC_01972	2.01e-144	-	-	-	K	-	-	-	helix_turn_helix, Deoxyribose operon repressor
HECMCFGC_01973	2.22e-126	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HECMCFGC_01974	4.78e-120	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HECMCFGC_01975	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HECMCFGC_01976	8.75e-281	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HECMCFGC_01977	4.07e-245	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HECMCFGC_01978	1.6e-175	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECMCFGC_01979	1.08e-174	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
HECMCFGC_01980	5.39e-196	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01981	1.83e-213	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01982	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HECMCFGC_01983	3.84e-185	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HECMCFGC_01984	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01985	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECMCFGC_01986	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HECMCFGC_01987	2.47e-226	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HECMCFGC_01988	2.92e-87	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECMCFGC_01989	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HECMCFGC_01990	7.93e-59	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HECMCFGC_01991	6.15e-299	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HECMCFGC_01992	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HECMCFGC_01993	3.61e-158	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HECMCFGC_01994	2.17e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HECMCFGC_01995	3.48e-305	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HECMCFGC_01996	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HECMCFGC_01997	2.7e-172	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HECMCFGC_01998	1.33e-266	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HECMCFGC_01999	5.14e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HECMCFGC_02000	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HECMCFGC_02001	4.05e-284	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HECMCFGC_02002	1.26e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HECMCFGC_02003	7.56e-285	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HECMCFGC_02004	1.92e-202	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HECMCFGC_02005	7.47e-156	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HECMCFGC_02006	5.55e-79	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HECMCFGC_02007	7.3e-221	-	-	-	S	ko:K21688	-	ko00000	G5
HECMCFGC_02008	6.72e-275	-	-	-	-	-	-	-	-
HECMCFGC_02009	3.15e-312	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HECMCFGC_02010	2.88e-91	-	-	-	-	-	-	-	-
HECMCFGC_02012	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HECMCFGC_02013	1.6e-125	-	-	-	K	-	-	-	Transposase IS116 IS110 IS902
HECMCFGC_02014	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HECMCFGC_02015	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HECMCFGC_02016	5.33e-14	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HECMCFGC_02017	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HECMCFGC_02018	2.35e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECMCFGC_02019	0.0	galA	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	Glycosyl hydrolase family 53
HECMCFGC_02020	1.01e-107	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HECMCFGC_02021	3.4e-177	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HECMCFGC_02022	2.25e-300	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HECMCFGC_02023	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HECMCFGC_02024	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
HECMCFGC_02025	4.22e-293	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HECMCFGC_02026	1.03e-139	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HECMCFGC_02027	7.51e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HECMCFGC_02029	1.92e-238	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HECMCFGC_02030	1.83e-175	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
HECMCFGC_02031	2.93e-58	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HECMCFGC_02033	1.99e-76	-	-	-	C	-	-	-	Polysaccharide pyruvyl transferase
HECMCFGC_02034	3.95e-143	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HECMCFGC_02035	2.48e-56	XK27_01805	-	-	M	-	-	-	Glycosyltransferase like family 2
HECMCFGC_02036	2.34e-218	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
HECMCFGC_02037	2.01e-153	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HECMCFGC_02038	1.53e-307	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HECMCFGC_02039	6.11e-189	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HECMCFGC_02040	1.66e-220	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HECMCFGC_02041	4.85e-278	-	-	-	GK	-	-	-	ROK family
HECMCFGC_02042	2e-203	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HECMCFGC_02043	0.0	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
HECMCFGC_02044	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HECMCFGC_02045	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HECMCFGC_02046	2.15e-155	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HECMCFGC_02047	6.2e-69	-	-	-	L	-	-	-	Helix-turn-helix domain
HECMCFGC_02049	1.4e-278	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HECMCFGC_02050	4.68e-295	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HECMCFGC_02051	1.24e-183	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HECMCFGC_02052	3.45e-218	guaD	3.5.4.28, 3.5.4.3, 3.5.4.31	-	F	ko:K01487,ko:K12960	ko00230,ko00270,ko01100,map00230,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HECMCFGC_02053	4.12e-148	-	-	-	F	-	-	-	Permease family
HECMCFGC_02054	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HECMCFGC_02055	2.54e-176	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HECMCFGC_02056	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECMCFGC_02057	1.39e-155	-	-	-	-	-	-	-	-
HECMCFGC_02060	2.24e-148	-	-	-	K	-	-	-	WHG domain
HECMCFGC_02061	3.88e-120	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
HECMCFGC_02062	2.32e-62	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HECMCFGC_02063	2.09e-18	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HECMCFGC_02064	5.39e-43	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain