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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NEPFMCGO_00001	2.09e-67	-	-	-	M	-	-	-	Parallel beta-helix repeats
NEPFMCGO_00002	2.47e-115	-	-	-	K	-	-	-	MarR family
NEPFMCGO_00003	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_00004	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NEPFMCGO_00005	2.52e-217	-	-	-	S	-	-	-	Patatin-like phospholipase
NEPFMCGO_00006	3.71e-194	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NEPFMCGO_00007	1.04e-215	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NEPFMCGO_00008	1.18e-147	-	-	-	S	-	-	-	Vitamin K epoxide reductase
NEPFMCGO_00009	1.04e-212	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
NEPFMCGO_00010	5.4e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
NEPFMCGO_00011	2.28e-313	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
NEPFMCGO_00012	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NEPFMCGO_00013	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NEPFMCGO_00014	5.62e-191	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NEPFMCGO_00015	2.24e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
NEPFMCGO_00016	2.07e-182	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NEPFMCGO_00017	1.52e-81	-	-	-	S	-	-	-	Thiamine-binding protein
NEPFMCGO_00018	9.49e-207	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NEPFMCGO_00019	3.43e-291	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
NEPFMCGO_00020	1.62e-110	-	-	-	-	-	-	-	-
NEPFMCGO_00021	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NEPFMCGO_00022	3.95e-199	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEPFMCGO_00023	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
NEPFMCGO_00024	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
NEPFMCGO_00025	3.86e-313	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEPFMCGO_00026	3.13e-292	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEPFMCGO_00027	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEPFMCGO_00028	1.11e-55	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NEPFMCGO_00029	1.65e-191	-	-	-	V	-	-	-	DivIVA protein
NEPFMCGO_00030	4.6e-148	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEPFMCGO_00031	1.89e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NEPFMCGO_00033	1.25e-82	-	-	-	-	-	-	-	-
NEPFMCGO_00034	4.34e-219	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NEPFMCGO_00036	5.51e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEPFMCGO_00037	1.02e-299	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
NEPFMCGO_00038	2.48e-202	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
NEPFMCGO_00039	4.41e-279	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
NEPFMCGO_00040	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEPFMCGO_00041	3.17e-187	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
NEPFMCGO_00042	9.11e-57	-	-	-	-	-	-	-	-
NEPFMCGO_00043	2.54e-57	-	-	-	-	-	-	-	-
NEPFMCGO_00044	6.6e-13	-	-	-	-	-	-	-	-
NEPFMCGO_00046	6.76e-298	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
NEPFMCGO_00047	2.07e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NEPFMCGO_00048	3.23e-298	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NEPFMCGO_00049	0.0	-	-	-	I	-	-	-	acetylesterase activity
NEPFMCGO_00050	2.49e-183	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NEPFMCGO_00051	2.53e-198	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEPFMCGO_00052	9.58e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
NEPFMCGO_00053	2.65e-23	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NEPFMCGO_00054	5.66e-50	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NEPFMCGO_00055	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
NEPFMCGO_00056	4.16e-168	-	-	-	S	-	-	-	zinc-ribbon domain
NEPFMCGO_00057	1.9e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
NEPFMCGO_00058	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
NEPFMCGO_00059	1.75e-07	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEPFMCGO_00060	4.63e-254	-	-	-	K	-	-	-	WYL domain
NEPFMCGO_00061	1.35e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
NEPFMCGO_00063	6.79e-220	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
NEPFMCGO_00064	4.32e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
NEPFMCGO_00065	1.45e-11	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NEPFMCGO_00066	3.8e-232	-	-	-	S	-	-	-	Protein conserved in bacteria
NEPFMCGO_00068	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEPFMCGO_00069	1.46e-282	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEPFMCGO_00070	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
NEPFMCGO_00071	1.4e-148	-	-	-	-	-	-	-	-
NEPFMCGO_00072	3.31e-157	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEPFMCGO_00073	2.29e-165	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
NEPFMCGO_00074	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
NEPFMCGO_00075	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NEPFMCGO_00076	5.22e-267	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NEPFMCGO_00077	4.67e-61	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator Superfamily
NEPFMCGO_00078	1.54e-228	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NEPFMCGO_00079	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
NEPFMCGO_00080	2.07e-156	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
NEPFMCGO_00081	2.02e-216	-	-	-	-	-	-	-	-
NEPFMCGO_00082	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEPFMCGO_00083	1.96e-226	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NEPFMCGO_00084	7.83e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEPFMCGO_00085	3.54e-165	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEPFMCGO_00086	2.4e-65	-	-	-	M	-	-	-	Lysin motif
NEPFMCGO_00087	2.55e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEPFMCGO_00088	4.59e-290	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NEPFMCGO_00089	0.0	-	-	-	L	-	-	-	DNA helicase
NEPFMCGO_00090	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NEPFMCGO_00091	8.62e-253	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEPFMCGO_00092	9.33e-96	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NEPFMCGO_00093	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
NEPFMCGO_00094	1.75e-231	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEPFMCGO_00095	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEPFMCGO_00096	8.76e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEPFMCGO_00097	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEPFMCGO_00098	4.49e-297	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
NEPFMCGO_00099	3.15e-276	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEPFMCGO_00100	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NEPFMCGO_00101	1.68e-231	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
NEPFMCGO_00104	2.9e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEPFMCGO_00105	3.06e-300	-	-	-	G	-	-	-	Major Facilitator Superfamily
NEPFMCGO_00106	8.24e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NEPFMCGO_00107	2.17e-285	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NEPFMCGO_00108	9.38e-167	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NEPFMCGO_00109	1.68e-275	-	-	-	GK	-	-	-	ROK family
NEPFMCGO_00110	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEPFMCGO_00111	4.41e-309	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
NEPFMCGO_00112	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NEPFMCGO_00113	5.3e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00114	2.16e-248	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00115	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEPFMCGO_00116	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
NEPFMCGO_00117	4.35e-125	-	-	-	F	-	-	-	NUDIX domain
NEPFMCGO_00119	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
NEPFMCGO_00120	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NEPFMCGO_00121	2.31e-174	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NEPFMCGO_00122	8.51e-308	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
NEPFMCGO_00123	1.32e-290	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
NEPFMCGO_00124	2.97e-243	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
NEPFMCGO_00125	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEPFMCGO_00126	4.05e-148	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEPFMCGO_00127	9.61e-84	-	-	-	-	-	-	-	-
NEPFMCGO_00128	6.49e-249	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NEPFMCGO_00129	8.91e-229	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NEPFMCGO_00131	6.06e-119	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEPFMCGO_00132	3.39e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEPFMCGO_00133	3.98e-171	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
NEPFMCGO_00134	3.69e-10	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
NEPFMCGO_00135	3.29e-82	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
NEPFMCGO_00136	3.07e-137	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEPFMCGO_00137	1.92e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
NEPFMCGO_00138	1.29e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEPFMCGO_00139	4.62e-226	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
NEPFMCGO_00140	2.17e-193	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
NEPFMCGO_00141	8.34e-194	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEPFMCGO_00142	4.75e-126	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEPFMCGO_00143	1.03e-196	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
NEPFMCGO_00144	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NEPFMCGO_00145	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
NEPFMCGO_00146	4.74e-211	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
NEPFMCGO_00147	2.93e-297	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
NEPFMCGO_00148	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
NEPFMCGO_00149	2.61e-109	-	-	-	-	-	-	-	-
NEPFMCGO_00150	2.38e-252	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NEPFMCGO_00151	1.41e-243	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
NEPFMCGO_00152	2.2e-55	-	-	-	-	-	-	-	-
NEPFMCGO_00153	1.36e-235	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NEPFMCGO_00154	1.13e-224	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00155	3.06e-211	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NEPFMCGO_00156	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEPFMCGO_00157	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NEPFMCGO_00158	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NEPFMCGO_00159	1.17e-214	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
NEPFMCGO_00160	4.35e-183	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
NEPFMCGO_00161	4.51e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
NEPFMCGO_00162	2.63e-313	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEPFMCGO_00163	3.18e-140	-	-	-	-	-	-	-	-
NEPFMCGO_00164	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NEPFMCGO_00165	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NEPFMCGO_00167	4.62e-223	-	-	-	S	-	-	-	Protein conserved in bacteria
NEPFMCGO_00168	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
NEPFMCGO_00169	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEPFMCGO_00170	7.86e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEPFMCGO_00171	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEPFMCGO_00172	6.4e-173	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NEPFMCGO_00173	1.29e-233	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEPFMCGO_00174	5.29e-177	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
NEPFMCGO_00175	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
NEPFMCGO_00176	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
NEPFMCGO_00177	1.98e-203	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
NEPFMCGO_00178	1.74e-27	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NEPFMCGO_00179	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NEPFMCGO_00180	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
NEPFMCGO_00181	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
NEPFMCGO_00182	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
NEPFMCGO_00183	0.0	-	-	-	S	-	-	-	PGAP1-like protein
NEPFMCGO_00185	3.08e-114	-	-	-	-	-	-	-	-
NEPFMCGO_00186	1.35e-196	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NEPFMCGO_00187	3.75e-245	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NEPFMCGO_00188	1.25e-121	-	-	-	-	-	-	-	-
NEPFMCGO_00189	1.14e-228	-	-	-	S	-	-	-	Protein of unknown function DUF58
NEPFMCGO_00190	2.47e-251	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NEPFMCGO_00191	1.29e-185	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEPFMCGO_00192	5.79e-100	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NEPFMCGO_00193	3.01e-58	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NEPFMCGO_00194	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEPFMCGO_00195	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
NEPFMCGO_00196	3.44e-232	-	-	-	-	-	-	-	-
NEPFMCGO_00197	1.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
NEPFMCGO_00198	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPFMCGO_00199	1.23e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NEPFMCGO_00200	1.39e-256	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
NEPFMCGO_00201	9.86e-237	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
NEPFMCGO_00202	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
NEPFMCGO_00204	4.76e-71	-	2.7.13.3	-	T	ko:K07675,ko:K20263	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEPFMCGO_00205	2.38e-298	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
NEPFMCGO_00206	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
NEPFMCGO_00207	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NEPFMCGO_00208	6.73e-51	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NEPFMCGO_00209	8.07e-24	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NEPFMCGO_00210	8.23e-78	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
NEPFMCGO_00211	2.08e-180	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
NEPFMCGO_00212	6.89e-195	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NEPFMCGO_00213	2.01e-142	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00214	6.3e-251	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00215	2.9e-254	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
NEPFMCGO_00216	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
NEPFMCGO_00217	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
NEPFMCGO_00219	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEPFMCGO_00220	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_00221	5.43e-133	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEPFMCGO_00222	5.43e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NEPFMCGO_00223	5.59e-269	-	-	-	E	-	-	-	Aminotransferase class I and II
NEPFMCGO_00224	5.17e-177	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_00225	5.39e-88	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
NEPFMCGO_00226	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEPFMCGO_00227	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEPFMCGO_00228	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEPFMCGO_00229	2.75e-268	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NEPFMCGO_00230	2.88e-203	-	-	-	S	-	-	-	Protein conserved in bacteria
NEPFMCGO_00233	5.27e-21	-	-	-	-	-	-	-	-
NEPFMCGO_00235	1.34e-24	-	-	-	-	-	-	-	-
NEPFMCGO_00236	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NEPFMCGO_00237	4.1e-180	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
NEPFMCGO_00238	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NEPFMCGO_00239	2.82e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
NEPFMCGO_00240	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
NEPFMCGO_00242	1.92e-219	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
NEPFMCGO_00243	2.22e-190	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_00244	3.12e-250	-	-	-	-	-	-	-	-
NEPFMCGO_00245	2.32e-296	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
NEPFMCGO_00246	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
NEPFMCGO_00247	2.38e-262	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEPFMCGO_00248	9.54e-43	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NEPFMCGO_00249	8.39e-123	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NEPFMCGO_00250	5.77e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEPFMCGO_00251	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEPFMCGO_00252	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
NEPFMCGO_00253	2.04e-194	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
NEPFMCGO_00254	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEPFMCGO_00255	1.03e-131	-	-	-	D	-	-	-	Septum formation initiator
NEPFMCGO_00256	1.21e-135	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
NEPFMCGO_00257	2.41e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NEPFMCGO_00259	3.61e-125	-	-	-	-	-	-	-	-
NEPFMCGO_00260	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
NEPFMCGO_00261	8.53e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
NEPFMCGO_00262	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEPFMCGO_00265	2.65e-139	-	-	-	-	-	-	-	-
NEPFMCGO_00266	7.92e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
NEPFMCGO_00267	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPFMCGO_00268	6.69e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NEPFMCGO_00269	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
NEPFMCGO_00270	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
NEPFMCGO_00271	2.82e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NEPFMCGO_00272	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
NEPFMCGO_00273	0.0	-	-	-	-	-	-	-	-
NEPFMCGO_00274	1.05e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NEPFMCGO_00275	4.52e-198	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
NEPFMCGO_00276	3.82e-167	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
NEPFMCGO_00277	4.38e-91	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
NEPFMCGO_00278	2.06e-259	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPFMCGO_00279	9.32e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
NEPFMCGO_00280	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEPFMCGO_00281	2.33e-130	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
NEPFMCGO_00282	1.42e-105	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NEPFMCGO_00283	2.15e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NEPFMCGO_00284	1.91e-208	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_00285	2.27e-227	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NEPFMCGO_00286	7e-210	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEPFMCGO_00287	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NEPFMCGO_00288	6.44e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEPFMCGO_00289	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEPFMCGO_00290	2.91e-230	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
NEPFMCGO_00291	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
NEPFMCGO_00292	8.13e-141	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NEPFMCGO_00294	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
NEPFMCGO_00295	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEPFMCGO_00296	2.56e-219	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
NEPFMCGO_00297	3.55e-158	-	-	-	L	-	-	-	NUDIX domain
NEPFMCGO_00298	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
NEPFMCGO_00299	5.92e-280	-	-	-	-	-	-	-	-
NEPFMCGO_00301	2.75e-152	-	-	-	L	-	-	-	Phage integrase family
NEPFMCGO_00302	7.52e-144	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
NEPFMCGO_00303	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEPFMCGO_00304	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEPFMCGO_00305	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
NEPFMCGO_00306	3.74e-103	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NEPFMCGO_00307	6.63e-111	-	-	-	V	-	-	-	Abi-like protein
NEPFMCGO_00308	1.03e-40	-	-	-	S	-	-	-	KAP family P-loop domain
NEPFMCGO_00310	4.06e-21	gntR	-	-	K	-	-	-	FCD
NEPFMCGO_00311	9.23e-81	-	-	-	L	-	-	-	protein secretion by the type IV secretion system
NEPFMCGO_00313	3.73e-139	-	-	-	S	-	-	-	Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A
NEPFMCGO_00314	5.1e-57	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_00315	9.45e-17	-	-	-	L	-	-	-	Integrase core domain
NEPFMCGO_00316	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NEPFMCGO_00317	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NEPFMCGO_00318	7.55e-243	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
NEPFMCGO_00319	4.91e-150	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
NEPFMCGO_00320	5.16e-152	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NEPFMCGO_00321	1.22e-290	-	-	-	T	-	-	-	Histidine kinase
NEPFMCGO_00322	1.2e-54	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
NEPFMCGO_00323	1.46e-236	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_00324	2.28e-289	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NEPFMCGO_00325	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NEPFMCGO_00326	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NEPFMCGO_00327	1.6e-41	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
NEPFMCGO_00328	7.12e-128	-	-	-	-	-	-	-	-
NEPFMCGO_00329	5.03e-251	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
NEPFMCGO_00330	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NEPFMCGO_00331	2.71e-196	-	-	-	D	-	-	-	bacterial-type flagellum organization
NEPFMCGO_00332	6.74e-244	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
NEPFMCGO_00333	2.62e-157	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
NEPFMCGO_00335	1.3e-20	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
NEPFMCGO_00336	3.96e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
NEPFMCGO_00337	8.53e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
NEPFMCGO_00338	4.42e-272	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
NEPFMCGO_00339	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
NEPFMCGO_00340	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEPFMCGO_00341	2.68e-175	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NEPFMCGO_00342	6.76e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NEPFMCGO_00344	7.91e-271	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEPFMCGO_00345	1.77e-148	-	-	-	-	-	-	-	-
NEPFMCGO_00346	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
NEPFMCGO_00348	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NEPFMCGO_00349	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NEPFMCGO_00350	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
NEPFMCGO_00351	3.64e-295	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NEPFMCGO_00352	7.72e-174	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
NEPFMCGO_00353	0.0	-	-	-	M	-	-	-	PA domain
NEPFMCGO_00354	5.71e-245	-	-	-	I	-	-	-	PAP2 superfamily
NEPFMCGO_00355	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEPFMCGO_00356	2.08e-158	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEPFMCGO_00357	1.74e-271	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NEPFMCGO_00358	3.82e-255	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NEPFMCGO_00359	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
NEPFMCGO_00360	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEPFMCGO_00361	2.46e-96	-	-	-	S	-	-	-	Fic/DOC family
NEPFMCGO_00362	1.01e-256	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEPFMCGO_00363	1.44e-31	-	-	-	G	-	-	-	MFS/sugar transport protein
NEPFMCGO_00364	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
NEPFMCGO_00365	7.95e-149	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
NEPFMCGO_00366	4.13e-294	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
NEPFMCGO_00367	1.08e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NEPFMCGO_00368	7.87e-261	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NEPFMCGO_00369	9.06e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_00370	3.28e-102	-	-	-	S	-	-	-	FMN_bind
NEPFMCGO_00371	2.39e-164	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
NEPFMCGO_00372	1.01e-15	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NEPFMCGO_00373	2.83e-21	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NEPFMCGO_00374	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEPFMCGO_00375	5.95e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NEPFMCGO_00376	1.29e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NEPFMCGO_00377	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NEPFMCGO_00378	1.5e-44	-	-	-	Q	-	-	-	phosphatase activity
NEPFMCGO_00379	9.12e-103	-	-	-	-	-	-	-	-
NEPFMCGO_00380	3.1e-305	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NEPFMCGO_00381	4.74e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NEPFMCGO_00383	1.19e-219	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NEPFMCGO_00384	0.0	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	chlorophyll binding
NEPFMCGO_00385	6.39e-311	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
NEPFMCGO_00387	2.29e-106	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NEPFMCGO_00388	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_00389	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NEPFMCGO_00390	1.2e-105	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NEPFMCGO_00391	2.43e-23	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
NEPFMCGO_00392	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NEPFMCGO_00393	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
NEPFMCGO_00394	5.4e-252	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
NEPFMCGO_00395	1.93e-171	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEPFMCGO_00397	5.59e-273	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEPFMCGO_00398	2.1e-305	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
NEPFMCGO_00399	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
NEPFMCGO_00400	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
NEPFMCGO_00401	0.0	dinF	-	-	V	-	-	-	MatE
NEPFMCGO_00402	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NEPFMCGO_00403	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
NEPFMCGO_00404	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NEPFMCGO_00405	3.15e-44	-	-	-	S	-	-	-	granule-associated protein
NEPFMCGO_00406	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
NEPFMCGO_00407	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NEPFMCGO_00408	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
NEPFMCGO_00409	2.4e-296	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
NEPFMCGO_00410	9.77e-162	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEPFMCGO_00411	1.94e-213	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
NEPFMCGO_00412	3.24e-28	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NEPFMCGO_00413	1.85e-79	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NEPFMCGO_00414	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEPFMCGO_00415	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEPFMCGO_00416	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEPFMCGO_00417	3.79e-249	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NEPFMCGO_00418	6.51e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
NEPFMCGO_00419	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
NEPFMCGO_00420	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEPFMCGO_00421	2.38e-296	-	2.6.1.1	-	E	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NEPFMCGO_00422	3.12e-117	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
NEPFMCGO_00423	1.09e-94	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
NEPFMCGO_00424	0.0	-	-	-	S	-	-	-	domain protein
NEPFMCGO_00425	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEPFMCGO_00426	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NEPFMCGO_00427	1.57e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEPFMCGO_00428	7.28e-171	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
NEPFMCGO_00429	9.29e-169	-	-	-	-	-	-	-	-
NEPFMCGO_00430	1.16e-133	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NEPFMCGO_00432	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NEPFMCGO_00433	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NEPFMCGO_00434	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
NEPFMCGO_00435	1.46e-21	-	-	-	-	-	-	-	-
NEPFMCGO_00437	8.42e-265	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NEPFMCGO_00438	1.44e-187	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NEPFMCGO_00440	1.21e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEPFMCGO_00441	2.5e-96	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEPFMCGO_00442	6.61e-191	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEPFMCGO_00443	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEPFMCGO_00444	2.73e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEPFMCGO_00445	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEPFMCGO_00446	2.3e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NEPFMCGO_00447	3.5e-165	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NEPFMCGO_00448	3.93e-185	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NEPFMCGO_00449	0.0	-	-	-	-	-	-	-	-
NEPFMCGO_00450	3.9e-195	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
NEPFMCGO_00451	2.14e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NEPFMCGO_00452	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NEPFMCGO_00453	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
NEPFMCGO_00454	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
NEPFMCGO_00455	7.62e-126	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEPFMCGO_00456	5.97e-207	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
NEPFMCGO_00458	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
NEPFMCGO_00459	6.08e-153	-	-	-	-	-	-	-	-
NEPFMCGO_00460	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEPFMCGO_00461	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NEPFMCGO_00462	6.87e-114	xylR	-	-	K	ko:K02529,ko:K16210	-	ko00000,ko02000,ko03000	purine nucleotide biosynthetic process
NEPFMCGO_00463	5e-55	xylR	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
NEPFMCGO_00464	9.37e-35	-	-	-	K	-	-	-	purine nucleotide biosynthetic process
NEPFMCGO_00465	3.59e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NEPFMCGO_00466	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NEPFMCGO_00467	8.07e-105	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NEPFMCGO_00468	1.05e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEPFMCGO_00469	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEPFMCGO_00470	1.25e-127	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
NEPFMCGO_00471	5.13e-55	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NEPFMCGO_00472	3.96e-213	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
NEPFMCGO_00473	1.44e-20	-	-	-	L	-	-	-	Transposase, Mutator family
NEPFMCGO_00475	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
NEPFMCGO_00476	3.89e-241	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
NEPFMCGO_00477	1.28e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NEPFMCGO_00478	2.23e-164	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEPFMCGO_00479	3.7e-112	-	-	-	D	-	-	-	nuclear chromosome segregation
NEPFMCGO_00480	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NEPFMCGO_00481	1.13e-228	-	-	-	L	-	-	-	Excalibur calcium-binding domain
NEPFMCGO_00482	3.26e-276	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NEPFMCGO_00483	1.82e-311	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEPFMCGO_00484	2.95e-139	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NEPFMCGO_00486	1.03e-304	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NEPFMCGO_00487	6.31e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEPFMCGO_00488	9.24e-305	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NEPFMCGO_00489	5.44e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NEPFMCGO_00490	9.05e-258	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
NEPFMCGO_00491	1.72e-218	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NEPFMCGO_00492	3.66e-231	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
NEPFMCGO_00493	1.29e-189	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEPFMCGO_00494	3.67e-181	-	-	-	S	-	-	-	Protein conserved in bacteria
NEPFMCGO_00496	8.03e-311	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
NEPFMCGO_00498	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
NEPFMCGO_00499	2.55e-224	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
NEPFMCGO_00500	5.06e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEPFMCGO_00501	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEPFMCGO_00503	0.0	-	-	-	T	-	-	-	Forkhead associated domain
NEPFMCGO_00504	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
NEPFMCGO_00505	2.87e-56	-	-	-	-	-	-	-	-
NEPFMCGO_00506	1e-139	-	-	-	NO	-	-	-	SAF
NEPFMCGO_00507	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
NEPFMCGO_00508	1.63e-153	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
NEPFMCGO_00509	9.98e-121	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NEPFMCGO_00510	1.66e-258	-	-	-	-	-	-	-	-
NEPFMCGO_00511	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEPFMCGO_00512	1.28e-115	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NEPFMCGO_00516	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
NEPFMCGO_00517	9.07e-279	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NEPFMCGO_00518	3.55e-81	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
NEPFMCGO_00519	4.52e-282	dapC	-	-	E	-	-	-	Aminotransferase class I and II
NEPFMCGO_00520	5.1e-310	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEPFMCGO_00522	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
NEPFMCGO_00523	2.82e-147	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
NEPFMCGO_00524	5.92e-155	-	-	-	-	-	-	-	-
NEPFMCGO_00525	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NEPFMCGO_00526	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEPFMCGO_00527	1.71e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NEPFMCGO_00528	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
NEPFMCGO_00529	1.5e-298	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NEPFMCGO_00530	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NEPFMCGO_00531	3.91e-213	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NEPFMCGO_00533	2.27e-132	-	-	-	S	-	-	-	YwiC-like protein
NEPFMCGO_00534	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NEPFMCGO_00535	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEPFMCGO_00536	1.34e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NEPFMCGO_00537	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEPFMCGO_00538	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEPFMCGO_00539	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEPFMCGO_00540	2.21e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEPFMCGO_00541	2.73e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEPFMCGO_00542	2.71e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEPFMCGO_00543	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NEPFMCGO_00544	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEPFMCGO_00545	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEPFMCGO_00546	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEPFMCGO_00547	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEPFMCGO_00548	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEPFMCGO_00549	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEPFMCGO_00550	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEPFMCGO_00551	8.85e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEPFMCGO_00552	2.04e-149	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEPFMCGO_00553	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
NEPFMCGO_00554	1.51e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NEPFMCGO_00555	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEPFMCGO_00556	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEPFMCGO_00557	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEPFMCGO_00558	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NEPFMCGO_00559	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEPFMCGO_00560	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEPFMCGO_00561	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEPFMCGO_00562	3.77e-95	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NEPFMCGO_00563	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
NEPFMCGO_00564	4.57e-218	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEPFMCGO_00565	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
NEPFMCGO_00566	5.51e-199	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
NEPFMCGO_00568	2.96e-124	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
NEPFMCGO_00569	2.11e-223	-	-	-	-	-	-	-	-
NEPFMCGO_00570	1.16e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NEPFMCGO_00571	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEPFMCGO_00572	2.12e-115	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEPFMCGO_00573	4.14e-295	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEPFMCGO_00574	2.23e-298	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
NEPFMCGO_00575	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEPFMCGO_00576	8.06e-141	-	-	-	-	-	-	-	-
NEPFMCGO_00577	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
NEPFMCGO_00578	1.28e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEPFMCGO_00579	4.16e-259	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEPFMCGO_00580	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
NEPFMCGO_00581	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NEPFMCGO_00582	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NEPFMCGO_00583	1.71e-09	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
NEPFMCGO_00584	0.000112	-	-	-	O	ko:K18546	-	ko00000,ko01000,ko01002	Peptidase s1 and s6 chymotrypsin hap
NEPFMCGO_00585	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
NEPFMCGO_00586	3.56e-198	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NEPFMCGO_00587	1.32e-272	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NEPFMCGO_00588	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
NEPFMCGO_00589	1.5e-298	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEPFMCGO_00591	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
NEPFMCGO_00593	1.51e-121	-	-	-	-	-	-	-	-
NEPFMCGO_00594	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEPFMCGO_00595	1.46e-237	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
NEPFMCGO_00596	4.79e-180	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NEPFMCGO_00598	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEPFMCGO_00599	2.24e-161	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NEPFMCGO_00600	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
NEPFMCGO_00601	0.0	pspC	-	-	KT	-	-	-	PspC domain
NEPFMCGO_00602	8.49e-184	-	-	-	-	-	-	-	-
NEPFMCGO_00603	2.25e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
NEPFMCGO_00604	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
NEPFMCGO_00605	7.45e-278	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
NEPFMCGO_00607	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NEPFMCGO_00608	2.37e-223	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
NEPFMCGO_00609	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEPFMCGO_00610	9.33e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NEPFMCGO_00611	2.54e-285	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPFMCGO_00612	5.39e-52	-	-	-	-	-	-	-	-
NEPFMCGO_00613	2.47e-273	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEPFMCGO_00614	8.29e-229	-	-	-	S	-	-	-	CHAP domain
NEPFMCGO_00615	5.28e-157	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
NEPFMCGO_00616	7.58e-244	-	-	-	T	-	-	-	Universal stress protein family
NEPFMCGO_00617	5.29e-95	-	-	-	O	-	-	-	OsmC-like protein
NEPFMCGO_00618	4.99e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEPFMCGO_00619	3.16e-164	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
NEPFMCGO_00620	2.34e-124	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
NEPFMCGO_00621	4.43e-250	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NEPFMCGO_00622	1.02e-46	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
NEPFMCGO_00623	3.56e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_00624	3.21e-269	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NEPFMCGO_00625	4.37e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NEPFMCGO_00626	2.87e-14	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NEPFMCGO_00627	6.95e-238	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEPFMCGO_00628	1.29e-198	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_00629	5.39e-181	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
NEPFMCGO_00630	5.37e-202	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00631	5.49e-215	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00632	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NEPFMCGO_00633	2.65e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NEPFMCGO_00634	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEPFMCGO_00635	5.35e-73	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
NEPFMCGO_00636	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NEPFMCGO_00637	2.28e-130	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NEPFMCGO_00638	6.23e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
NEPFMCGO_00639	1.89e-24	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NEPFMCGO_00640	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NEPFMCGO_00641	7.3e-24	-	-	-	L	-	-	-	Helix-turn-helix domain
NEPFMCGO_00642	1.47e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
NEPFMCGO_00643	8.59e-23	-	-	-	K	-	-	-	Helix-turn-helix domain
NEPFMCGO_00644	5.98e-134	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEPFMCGO_00645	1.81e-68	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain protein
NEPFMCGO_00646	5.22e-51	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NEPFMCGO_00647	2.72e-307	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
NEPFMCGO_00648	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NEPFMCGO_00649	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEPFMCGO_00650	5.61e-72	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NEPFMCGO_00651	1.84e-50	-	-	-	S	-	-	-	Aldo/keto reductase family
NEPFMCGO_00652	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
NEPFMCGO_00653	1.25e-178	hflK	-	-	O	-	-	-	prohibitin homologues
NEPFMCGO_00654	6.06e-309	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NEPFMCGO_00655	1.01e-294	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NEPFMCGO_00656	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
NEPFMCGO_00657	1.42e-287	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NEPFMCGO_00658	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_00659	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NEPFMCGO_00660	1.63e-47	-	-	-	K	-	-	-	MerR, DNA binding
NEPFMCGO_00661	3.49e-248	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
NEPFMCGO_00662	2.4e-130	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
NEPFMCGO_00663	1.5e-313	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
NEPFMCGO_00664	6.17e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NEPFMCGO_00665	3.85e-186	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NEPFMCGO_00666	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
NEPFMCGO_00667	2.22e-153	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NEPFMCGO_00668	5.91e-74	-	-	-	-	-	-	-	-
NEPFMCGO_00669	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEPFMCGO_00671	0.0	-	-	-	L	-	-	-	PIF1-like helicase
NEPFMCGO_00672	5.5e-203	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NEPFMCGO_00673	1.11e-155	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NEPFMCGO_00674	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NEPFMCGO_00675	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NEPFMCGO_00676	2.04e-258	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
NEPFMCGO_00677	2.13e-150	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
NEPFMCGO_00678	6.64e-234	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEPFMCGO_00679	1.17e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEPFMCGO_00680	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
NEPFMCGO_00682	1.88e-249	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
NEPFMCGO_00683	2.74e-209	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
NEPFMCGO_00684	4.72e-240	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NEPFMCGO_00685	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
NEPFMCGO_00686	1.46e-134	-	-	-	-	-	-	-	-
NEPFMCGO_00687	2.55e-215	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
NEPFMCGO_00688	9.71e-190	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NEPFMCGO_00689	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
NEPFMCGO_00690	1.23e-210	-	-	-	EG	-	-	-	EamA-like transporter family
NEPFMCGO_00691	4.12e-06	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_00692	7.61e-146	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NEPFMCGO_00693	2.37e-187	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NEPFMCGO_00695	5.03e-17	-	-	-	L	-	-	-	Transposase
NEPFMCGO_00696	4.48e-07	-	-	-	L	-	-	-	Transposase
NEPFMCGO_00697	7.33e-271	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_00698	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
NEPFMCGO_00699	6.24e-45	-	-	-	C	-	-	-	Aldo/keto reductase family
NEPFMCGO_00700	8.22e-96	-	-	-	EGP	-	-	-	Major facilitator superfamily
NEPFMCGO_00701	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NEPFMCGO_00702	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
NEPFMCGO_00703	1.03e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NEPFMCGO_00704	6.17e-144	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NEPFMCGO_00706	2.77e-33	-	-	-	S	-	-	-	DUF218 domain
NEPFMCGO_00707	1.31e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
NEPFMCGO_00708	3.77e-202	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
NEPFMCGO_00709	8.71e-148	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEPFMCGO_00710	1.22e-134	-	-	-	-	-	-	-	-
NEPFMCGO_00711	1.99e-73	-	-	-	M	-	-	-	domain, Protein
NEPFMCGO_00713	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
NEPFMCGO_00714	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
NEPFMCGO_00715	3.78e-219	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
NEPFMCGO_00716	6.73e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
NEPFMCGO_00717	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEPFMCGO_00718	4.37e-208	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NEPFMCGO_00719	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
NEPFMCGO_00720	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEPFMCGO_00721	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NEPFMCGO_00722	4.95e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEPFMCGO_00723	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
NEPFMCGO_00724	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NEPFMCGO_00725	9.2e-215	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_00726	2.29e-294	-	-	-	M	-	-	-	Glycosyl transferase family 21
NEPFMCGO_00727	0.0	-	-	-	S	-	-	-	AI-2E family transporter
NEPFMCGO_00728	1.49e-224	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEPFMCGO_00729	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
NEPFMCGO_00732	2.6e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
NEPFMCGO_00733	5.63e-255	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NEPFMCGO_00734	4.73e-196	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEPFMCGO_00736	4.73e-69	-	-	-	S	-	-	-	Helix-turn-helix domain
NEPFMCGO_00737	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NEPFMCGO_00738	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NEPFMCGO_00739	2.25e-16	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEPFMCGO_00740	1.68e-229	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NEPFMCGO_00741	1.03e-141	-	-	-	-	-	-	-	-
NEPFMCGO_00742	1.38e-239	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NEPFMCGO_00743	1.24e-280	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NEPFMCGO_00744	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NEPFMCGO_00745	1.27e-118	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEPFMCGO_00746	1.31e-37	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NEPFMCGO_00747	2.63e-121	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEPFMCGO_00748	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
NEPFMCGO_00749	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEPFMCGO_00750	7.39e-312	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
NEPFMCGO_00751	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEPFMCGO_00752	3.72e-204	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NEPFMCGO_00753	8.56e-289	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NEPFMCGO_00754	1.23e-58	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
NEPFMCGO_00756	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEPFMCGO_00757	1.61e-225	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
NEPFMCGO_00758	7.3e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEPFMCGO_00759	8.53e-290	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEPFMCGO_00760	2.88e-96	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NEPFMCGO_00761	3.01e-58	-	-	-	-	-	-	-	-
NEPFMCGO_00762	6.18e-196	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
NEPFMCGO_00763	6.86e-256	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
NEPFMCGO_00764	7.43e-32	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
NEPFMCGO_00765	1.03e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
NEPFMCGO_00766	1.47e-54	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NEPFMCGO_00767	4.85e-65	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEPFMCGO_00768	1.79e-61	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
NEPFMCGO_00769	4.11e-175	-	-	-	S	-	-	-	cobalamin synthesis protein
NEPFMCGO_00770	1.24e-206	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NEPFMCGO_00771	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
NEPFMCGO_00772	0.0	-	-	-	S	-	-	-	Putative esterase
NEPFMCGO_00773	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
NEPFMCGO_00774	2.54e-305	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NEPFMCGO_00775	3.47e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NEPFMCGO_00776	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEPFMCGO_00777	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
NEPFMCGO_00778	9.82e-45	-	-	-	-	-	-	-	-
NEPFMCGO_00779	8.12e-91	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEPFMCGO_00781	5.19e-32	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NEPFMCGO_00782	2.88e-184	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
NEPFMCGO_00783	2.2e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
NEPFMCGO_00784	3.47e-143	-	-	-	-	-	-	-	-
NEPFMCGO_00785	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
NEPFMCGO_00786	1.68e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NEPFMCGO_00787	9.07e-297	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEPFMCGO_00788	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
NEPFMCGO_00789	2.98e-289	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NEPFMCGO_00790	1.09e-254	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
NEPFMCGO_00792	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEPFMCGO_00793	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEPFMCGO_00794	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEPFMCGO_00795	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEPFMCGO_00796	0.0	-	-	-	S	-	-	-	Esterase-like activity of phytase
NEPFMCGO_00797	8.86e-280	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NEPFMCGO_00799	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEPFMCGO_00800	5.01e-151	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEPFMCGO_00801	1.4e-303	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NEPFMCGO_00802	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NEPFMCGO_00803	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NEPFMCGO_00804	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
NEPFMCGO_00805	3.52e-151	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NEPFMCGO_00806	0.0	-	-	-	T	-	-	-	Histidine kinase
NEPFMCGO_00807	1.46e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NEPFMCGO_00808	2.91e-174	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NEPFMCGO_00809	1.32e-210	-	-	-	EG	-	-	-	EamA-like transporter family
NEPFMCGO_00810	8.02e-171	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
NEPFMCGO_00811	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NEPFMCGO_00812	1.79e-235	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEPFMCGO_00813	2.21e-175	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NEPFMCGO_00814	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
NEPFMCGO_00815	6.37e-160	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEPFMCGO_00816	1.14e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NEPFMCGO_00817	8.48e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEPFMCGO_00818	3.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
NEPFMCGO_00819	7.39e-274	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEPFMCGO_00820	5.65e-95	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
NEPFMCGO_00823	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEPFMCGO_00824	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEPFMCGO_00825	1.53e-244	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEPFMCGO_00826	5.33e-141	-	-	-	-	-	-	-	-
NEPFMCGO_00827	2.92e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NEPFMCGO_00828	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
NEPFMCGO_00829	7.75e-258	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NEPFMCGO_00830	1.39e-157	-	-	-	-	-	-	-	-
NEPFMCGO_00831	7.69e-260	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEPFMCGO_00832	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NEPFMCGO_00833	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
NEPFMCGO_00834	4.61e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
NEPFMCGO_00835	8.81e-35	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NEPFMCGO_00836	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
NEPFMCGO_00837	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NEPFMCGO_00838	3.3e-300	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
NEPFMCGO_00839	2.58e-233	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
NEPFMCGO_00840	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
NEPFMCGO_00841	1.42e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NEPFMCGO_00842	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEPFMCGO_00844	1.03e-88	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
NEPFMCGO_00845	5.53e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NEPFMCGO_00847	6.06e-17	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_00848	8.5e-116	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
NEPFMCGO_00849	6.29e-312	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NEPFMCGO_00850	5.76e-08	-	-	-	L	-	-	-	Transposase DDE domain
NEPFMCGO_00852	1.47e-132	-	-	-	K	-	-	-	cell envelope-related transcriptional attenuator
NEPFMCGO_00853	7.99e-312	-	-	-	-	-	-	-	-
NEPFMCGO_00854	2.49e-230	-	-	-	S	ko:K21688	-	ko00000	G5
NEPFMCGO_00855	2.57e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
NEPFMCGO_00856	2.34e-153	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
NEPFMCGO_00857	2.14e-198	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NEPFMCGO_00859	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NEPFMCGO_00860	1.92e-108	-	-	-	L	ko:K07485	-	ko00000	Transposase
NEPFMCGO_00861	1.75e-22	-	-	-	L	ko:K07485	-	ko00000	Transposase
NEPFMCGO_00862	1.09e-205	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NEPFMCGO_00863	1.13e-182	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NEPFMCGO_00864	3.45e-314	lacZ3	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
NEPFMCGO_00865	7.92e-168	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00866	2.59e-180	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00867	3.07e-236	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEPFMCGO_00868	1.08e-150	-	-	-	K	-	-	-	Transcriptional regulator
NEPFMCGO_00869	1.26e-92	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NEPFMCGO_00870	1.2e-315	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
NEPFMCGO_00871	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
NEPFMCGO_00872	3.62e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NEPFMCGO_00873	1.04e-149	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
NEPFMCGO_00874	1.34e-172	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
NEPFMCGO_00875	0.0	pon1	-	-	M	-	-	-	Transglycosylase
NEPFMCGO_00876	4.61e-272	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
NEPFMCGO_00877	2.85e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NEPFMCGO_00878	7e-186	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NEPFMCGO_00879	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
NEPFMCGO_00880	3.98e-295	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
NEPFMCGO_00881	7.66e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NEPFMCGO_00882	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NEPFMCGO_00883	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NEPFMCGO_00884	3.1e-205	-	-	-	S	-	-	-	Membrane
NEPFMCGO_00885	9.1e-157	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEPFMCGO_00886	2.34e-54	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
NEPFMCGO_00887	1.84e-42	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
NEPFMCGO_00888	2.13e-234	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
NEPFMCGO_00889	2.08e-139	-	-	-	-	-	-	-	-
NEPFMCGO_00890	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEPFMCGO_00891	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEPFMCGO_00892	1.87e-124	-	-	-	T	-	-	-	Forkhead associated domain
NEPFMCGO_00893	8.9e-98	-	-	-	B	-	-	-	Belongs to the OprB family
NEPFMCGO_00894	2.25e-209	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
NEPFMCGO_00895	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
NEPFMCGO_00896	1.84e-298	-	-	-	S	-	-	-	Protein of unknown function DUF58
NEPFMCGO_00897	4.39e-316	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NEPFMCGO_00898	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
NEPFMCGO_00899	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NEPFMCGO_00900	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NEPFMCGO_00901	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
NEPFMCGO_00902	3.3e-202	-	-	-	K	-	-	-	-acetyltransferase
NEPFMCGO_00903	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
NEPFMCGO_00904	2.41e-84	gsiA	-	-	P	ko:K02031,ko:K02032,ko:K12371,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEPFMCGO_00905	1.24e-82	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
NEPFMCGO_00906	3.22e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NEPFMCGO_00907	2.35e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEPFMCGO_00908	6.97e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEPFMCGO_00909	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEPFMCGO_00910	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
NEPFMCGO_00911	4.43e-312	vpr	-	-	O	-	-	-	Subtilase family
NEPFMCGO_00912	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEPFMCGO_00913	1.58e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEPFMCGO_00914	0.0	-	-	-	S	-	-	-	zinc finger
NEPFMCGO_00915	1.43e-142	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NEPFMCGO_00916	6.29e-292	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
NEPFMCGO_00917	2.21e-47	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NEPFMCGO_00918	9.29e-169	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
NEPFMCGO_00919	8.74e-193	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
NEPFMCGO_00920	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
NEPFMCGO_00921	6.43e-232	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NEPFMCGO_00924	2.61e-259	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
NEPFMCGO_00925	1.47e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEPFMCGO_00926	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEPFMCGO_00927	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
NEPFMCGO_00928	1.06e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEPFMCGO_00930	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
NEPFMCGO_00931	1.99e-206	-	-	-	-	-	-	-	-
NEPFMCGO_00932	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
NEPFMCGO_00936	1.53e-96	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
NEPFMCGO_00937	1.22e-15	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
NEPFMCGO_00938	1.23e-293	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEPFMCGO_00939	2.07e-71	-	-	-	L	-	-	-	RelB antitoxin
NEPFMCGO_00941	7.64e-167	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NEPFMCGO_00942	1.01e-307	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NEPFMCGO_00944	1.28e-254	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
NEPFMCGO_00945	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
NEPFMCGO_00946	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
NEPFMCGO_00947	4.77e-276	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NEPFMCGO_00949	0.0	-	-	-	-	-	-	-	-
NEPFMCGO_00950	0.0	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
NEPFMCGO_00951	3.11e-155	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
NEPFMCGO_00952	6.45e-138	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NEPFMCGO_00953	9.18e-109	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
NEPFMCGO_00954	4.77e-224	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NEPFMCGO_00955	9.23e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEPFMCGO_00956	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NEPFMCGO_00957	5.38e-78	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NEPFMCGO_00958	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
NEPFMCGO_00959	3.89e-131	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
NEPFMCGO_00960	5.26e-280	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
NEPFMCGO_00961	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEPFMCGO_00962	2.39e-211	-	-	-	P	-	-	-	Cation efflux family
NEPFMCGO_00963	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NEPFMCGO_00964	8.06e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
NEPFMCGO_00965	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
NEPFMCGO_00966	1.72e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
NEPFMCGO_00967	4.42e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEPFMCGO_00968	1.66e-181	-	-	-	-	-	-	-	-
NEPFMCGO_00969	1.46e-145	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NEPFMCGO_00970	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NEPFMCGO_00971	9.01e-179	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEPFMCGO_00972	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
NEPFMCGO_00973	7.31e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NEPFMCGO_00975	1.4e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEPFMCGO_00976	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NEPFMCGO_00977	1.62e-151	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEPFMCGO_00978	5.38e-226	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
NEPFMCGO_00981	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NEPFMCGO_00982	4.21e-272	-	-	-	-	-	-	-	-
NEPFMCGO_00984	6.19e-263	-	-	-	-	-	-	-	-
NEPFMCGO_00986	2.62e-157	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
NEPFMCGO_00987	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
NEPFMCGO_00988	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_00989	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_00991	1.73e-221	-	-	-	K	-	-	-	Putative sugar-binding domain
NEPFMCGO_00992	1.46e-283	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NEPFMCGO_00993	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NEPFMCGO_00994	3.64e-219	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
NEPFMCGO_00995	2.22e-162	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
NEPFMCGO_00996	2.33e-81	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEPFMCGO_00997	9.11e-196	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NEPFMCGO_00998	6.64e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEPFMCGO_00999	8.13e-263	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NEPFMCGO_01000	3.38e-10	tnp3521a2	-	-	L	-	-	-	Integrase core domain
NEPFMCGO_01001	8.83e-75	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NEPFMCGO_01002	4.5e-316	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NEPFMCGO_01003	8.26e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NEPFMCGO_01004	3.18e-141	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NEPFMCGO_01007	6e-05	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NEPFMCGO_01008	4.24e-255	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NEPFMCGO_01009	2.55e-255	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NEPFMCGO_01010	2.87e-215	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
NEPFMCGO_01011	5.2e-173	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
NEPFMCGO_01012	3.74e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NEPFMCGO_01013	8.1e-315	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NEPFMCGO_01014	5.21e-272	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NEPFMCGO_01015	2.25e-264	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
NEPFMCGO_01016	2.06e-246	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
NEPFMCGO_01017	4.8e-77	-	-	-	-	-	-	-	-
NEPFMCGO_01019	3.5e-89	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
NEPFMCGO_01020	3.67e-30	-	-	-	-	-	-	-	-
NEPFMCGO_01021	1.39e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NEPFMCGO_01022	1.11e-49	-	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
NEPFMCGO_01023	5.77e-98	-	-	-	S	ko:K21688	-	ko00000	G5
NEPFMCGO_01024	3.85e-71	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
NEPFMCGO_01025	4.66e-212	-	-	-	M	-	-	-	Domain of unknown function (DUF1972)
NEPFMCGO_01026	5.75e-279	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NEPFMCGO_01027	1.31e-27	-	-	-	M	-	-	-	PFAM Glycosyl transferase, group 1
NEPFMCGO_01028	5.06e-108	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
NEPFMCGO_01029	1.06e-119	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NEPFMCGO_01030	7.86e-107	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEPFMCGO_01031	1.61e-159	-	-	-	-	-	-	-	-
NEPFMCGO_01032	8.72e-114	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
NEPFMCGO_01033	2.52e-161	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NEPFMCGO_01034	5.2e-45	-	-	-	M	-	-	-	Glycosyl transferase, family 2 glycosyl transferase family 8
NEPFMCGO_01036	1.59e-314	-	-	-	L	-	-	-	Transposase
NEPFMCGO_01037	9.32e-176	-	-	-	L	-	-	-	IstB-like ATP binding protein
NEPFMCGO_01038	1.91e-198	-	-	-	L	-	-	-	Transposase, Mutator family
NEPFMCGO_01039	1.84e-262	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NEPFMCGO_01040	4.18e-226	-	-	-	L	-	-	-	Tetratricopeptide repeat
NEPFMCGO_01041	3.08e-242	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
NEPFMCGO_01043	4.63e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NEPFMCGO_01044	2.64e-142	-	-	-	-	-	-	-	-
NEPFMCGO_01045	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
NEPFMCGO_01046	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
NEPFMCGO_01047	3.02e-233	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEPFMCGO_01048	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NEPFMCGO_01049	3.05e-159	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NEPFMCGO_01050	6.98e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NEPFMCGO_01051	2.21e-227	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_01052	3.76e-162	-	-	-	S	-	-	-	ABC-2 family transporter protein
NEPFMCGO_01053	3.24e-158	-	-	-	S	-	-	-	ABC-2 family transporter protein
NEPFMCGO_01054	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
NEPFMCGO_01055	2.81e-297	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEPFMCGO_01056	1.65e-116	-	-	-	-	-	-	-	-
NEPFMCGO_01057	5.93e-187	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEPFMCGO_01058	7.28e-243	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEPFMCGO_01060	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEPFMCGO_01061	7.12e-88	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEPFMCGO_01062	1.65e-177	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NEPFMCGO_01063	6.26e-101	-	-	-	S	-	-	-	Bacterial PH domain
NEPFMCGO_01064	0.0	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
NEPFMCGO_01065	5.6e-33	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEPFMCGO_01066	1.98e-126	-	-	-	-	-	-	-	-
NEPFMCGO_01068	3.05e-28	-	-	-	S	-	-	-	Putative viral replication protein
NEPFMCGO_01070	5.45e-63	traA	-	-	D	ko:K03466	-	ko00000,ko03036	ftsk spoiiie
NEPFMCGO_01075	4.5e-141	intA	-	-	L	-	-	-	Phage integrase family
NEPFMCGO_01077	2.65e-161	-	-	-	-	-	-	-	-
NEPFMCGO_01078	3.29e-169	-	-	-	C	-	-	-	Putative TM nitroreductase
NEPFMCGO_01079	2.91e-184	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
NEPFMCGO_01080	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
NEPFMCGO_01081	1.89e-189	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
NEPFMCGO_01082	7.59e-245	-	-	-	V	-	-	-	VanZ like family
NEPFMCGO_01083	5.99e-143	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NEPFMCGO_01084	4.95e-50	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NEPFMCGO_01085	2.52e-203	-	-	-	-	-	-	-	-
NEPFMCGO_01087	3.68e-68	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NEPFMCGO_01088	1.03e-43	-	-	-	EGP	ko:K03446,ko:K03466,ko:K03762,ko:K08217	-	br01600,ko00000,ko00002,ko01504,ko02000,ko03036	Major facilitator Superfamily
NEPFMCGO_01089	2.19e-223	-	-	-	M	-	-	-	heme binding
NEPFMCGO_01090	7.32e-101	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEPFMCGO_01091	1.01e-159	-	-	-	-	-	-	-	-
NEPFMCGO_01092	1.63e-169	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
NEPFMCGO_01093	4.2e-180	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	GHKL domain
NEPFMCGO_01094	1.29e-131	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NEPFMCGO_01095	1.42e-52	-	-	-	-	-	-	-	-
NEPFMCGO_01096	3.31e-127	-	-	-	-	-	-	-	-
NEPFMCGO_01097	5.74e-201	-	-	-	V	-	-	-	Putative peptidoglycan binding domain
NEPFMCGO_01098	2.24e-128	-	-	-	V	-	-	-	ABC transporter
NEPFMCGO_01099	1.66e-188	-	-	-	-	-	-	-	-
NEPFMCGO_01100	1.63e-234	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NEPFMCGO_01102	1.44e-90	-	-	-	-	-	-	-	-
NEPFMCGO_01104	3.01e-130	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
NEPFMCGO_01106	1.19e-51	-	-	-	K	-	-	-	Transcriptional regulator
NEPFMCGO_01107	6.05e-114	-	-	-	K	-	-	-	FR47-like protein
NEPFMCGO_01108	2.38e-151	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NEPFMCGO_01109	1.94e-83	-	-	-	K	-	-	-	Protein of unknown function, DUF488
NEPFMCGO_01110	5.12e-208	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEPFMCGO_01111	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01112	2.45e-185	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
NEPFMCGO_01113	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01114	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
NEPFMCGO_01115	1.41e-207	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NEPFMCGO_01116	2.45e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NEPFMCGO_01117	1.78e-212	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NEPFMCGO_01118	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NEPFMCGO_01119	1.57e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
NEPFMCGO_01120	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
NEPFMCGO_01121	5e-230	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NEPFMCGO_01122	3e-151	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
NEPFMCGO_01123	1.91e-201	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
NEPFMCGO_01124	9.98e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
NEPFMCGO_01125	6.55e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEPFMCGO_01127	8.4e-133	-	-	-	M	-	-	-	Peptidase family M23
NEPFMCGO_01128	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NEPFMCGO_01129	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
NEPFMCGO_01130	1.35e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
NEPFMCGO_01131	4.55e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
NEPFMCGO_01132	1.4e-115	-	-	-	-	-	-	-	-
NEPFMCGO_01133	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
NEPFMCGO_01134	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEPFMCGO_01135	3.07e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NEPFMCGO_01136	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEPFMCGO_01137	1.23e-161	-	-	-	S	-	-	-	alpha beta
NEPFMCGO_01138	5.19e-170	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NEPFMCGO_01139	7.62e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEPFMCGO_01140	1.17e-222	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
NEPFMCGO_01141	3.63e-290	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NEPFMCGO_01142	1.82e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEPFMCGO_01143	1.28e-94	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NEPFMCGO_01144	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NEPFMCGO_01145	1.43e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEPFMCGO_01146	5.59e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01147	4.73e-216	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NEPFMCGO_01149	7.02e-113	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
NEPFMCGO_01150	6.15e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NEPFMCGO_01151	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEPFMCGO_01152	2.74e-157	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NEPFMCGO_01153	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NEPFMCGO_01154	6.13e-58	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
NEPFMCGO_01155	1.36e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEPFMCGO_01156	3.56e-24	-	-	-	-	-	-	-	-
NEPFMCGO_01157	1.2e-63	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
NEPFMCGO_01158	1.17e-54	-	-	-	K	-	-	-	Helix-turn-helix
NEPFMCGO_01159	2.32e-283	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
NEPFMCGO_01160	2.32e-42	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
NEPFMCGO_01161	3.24e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NEPFMCGO_01162	1.02e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NEPFMCGO_01163	5.89e-171	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
NEPFMCGO_01164	1.97e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
NEPFMCGO_01165	3.81e-309	-	-	-	V	-	-	-	MatE
NEPFMCGO_01166	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NEPFMCGO_01167	1.31e-11	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NEPFMCGO_01169	2.8e-207	-	-	-	-	-	-	-	-
NEPFMCGO_01170	9.97e-245	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NEPFMCGO_01171	2.41e-23	-	-	-	K	-	-	-	MerR family regulatory protein
NEPFMCGO_01172	1.75e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEPFMCGO_01173	7.1e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEPFMCGO_01174	7.23e-200	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NEPFMCGO_01175	3.99e-231	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
NEPFMCGO_01176	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEPFMCGO_01177	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NEPFMCGO_01178	2.71e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NEPFMCGO_01179	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NEPFMCGO_01181	8.19e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NEPFMCGO_01182	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEPFMCGO_01183	5.84e-129	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
NEPFMCGO_01184	7.82e-263	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NEPFMCGO_01185	8.02e-228	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NEPFMCGO_01186	2.33e-30	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	EamA-like transporter family
NEPFMCGO_01187	1.1e-118	-	-	-	E	-	-	-	Rard protein
NEPFMCGO_01188	1.09e-38	-	-	-	-	-	-	-	-
NEPFMCGO_01189	9.82e-270	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NEPFMCGO_01190	2.76e-235	-	-	-	L	ko:K07485	-	ko00000	Transposase
NEPFMCGO_01191	1.85e-31	-	-	-	L	-	-	-	Helix-turn-helix domain
NEPFMCGO_01192	2.62e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEPFMCGO_01193	1.4e-151	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
NEPFMCGO_01194	4.79e-207	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
NEPFMCGO_01195	3.65e-232	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_01196	7.93e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
NEPFMCGO_01197	5.23e-107	-	-	-	-	-	-	-	-
NEPFMCGO_01198	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NEPFMCGO_01199	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
NEPFMCGO_01200	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
NEPFMCGO_01201	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
NEPFMCGO_01202	9.79e-18	-	-	-	S	ko:K07149	-	ko00000	Membrane
NEPFMCGO_01203	7.76e-311	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NEPFMCGO_01204	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEPFMCGO_01205	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NEPFMCGO_01206	4.63e-175	-	-	-	S	-	-	-	UPF0126 domain
NEPFMCGO_01208	1.11e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
NEPFMCGO_01209	1.57e-120	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NEPFMCGO_01210	2.34e-239	-	-	-	S	ko:K06889	-	ko00000	alpha beta
NEPFMCGO_01211	7.79e-303	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NEPFMCGO_01212	4.42e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
NEPFMCGO_01213	6.6e-257	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
NEPFMCGO_01214	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NEPFMCGO_01215	2.67e-234	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEPFMCGO_01216	0.0	corC	-	-	S	-	-	-	CBS domain
NEPFMCGO_01217	3.54e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEPFMCGO_01218	1.05e-253	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
NEPFMCGO_01219	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
NEPFMCGO_01220	1.26e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEPFMCGO_01222	1.78e-208	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
NEPFMCGO_01223	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEPFMCGO_01224	2.56e-141	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NEPFMCGO_01225	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NEPFMCGO_01226	3.62e-306	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEPFMCGO_01227	2.13e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NEPFMCGO_01228	2.06e-298	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
NEPFMCGO_01229	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
NEPFMCGO_01230	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEPFMCGO_01231	1.31e-05	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
NEPFMCGO_01232	1.41e-153	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NEPFMCGO_01233	4.78e-138	-	-	-	-	-	-	-	-
NEPFMCGO_01234	6.51e-103	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
NEPFMCGO_01235	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEPFMCGO_01236	6.4e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEPFMCGO_01237	7.19e-67	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
NEPFMCGO_01238	7.42e-246	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEPFMCGO_01239	7.68e-98	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEPFMCGO_01240	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEPFMCGO_01241	7.33e-50	-	-	-	-	-	-	-	-
NEPFMCGO_01242	4.03e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
NEPFMCGO_01243	1.78e-172	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
NEPFMCGO_01244	4.17e-186	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NEPFMCGO_01245	3.04e-297	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NEPFMCGO_01246	1.3e-108	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEPFMCGO_01247	1.9e-184	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NEPFMCGO_01248	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
NEPFMCGO_01249	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
NEPFMCGO_01250	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
NEPFMCGO_01251	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NEPFMCGO_01253	2.19e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEPFMCGO_01254	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
NEPFMCGO_01255	3.49e-175	-	-	-	-	-	-	-	-
NEPFMCGO_01256	1.23e-228	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NEPFMCGO_01257	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NEPFMCGO_01258	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
NEPFMCGO_01259	3.16e-111	-	-	-	L	-	-	-	Helix-turn-helix domain
NEPFMCGO_01260	3.1e-269	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEPFMCGO_01261	1.27e-219	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NEPFMCGO_01262	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NEPFMCGO_01263	4.28e-200	-	-	-	O	-	-	-	Thioredoxin
NEPFMCGO_01265	1.48e-270	rpfB	-	-	S	ko:K21688	-	ko00000	G5
NEPFMCGO_01266	8.19e-214	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEPFMCGO_01267	4.61e-214	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEPFMCGO_01268	6.94e-146	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NEPFMCGO_01269	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
NEPFMCGO_01270	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
NEPFMCGO_01271	0.0	-	-	-	M	-	-	-	Conserved repeat domain
NEPFMCGO_01272	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
NEPFMCGO_01273	7.27e-254	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEPFMCGO_01274	6.32e-309	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NEPFMCGO_01275	8.66e-229	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
NEPFMCGO_01277	1.98e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
NEPFMCGO_01278	2.02e-225	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
NEPFMCGO_01279	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NEPFMCGO_01280	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEPFMCGO_01281	9.43e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEPFMCGO_01282	2.66e-306	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEPFMCGO_01283	5.31e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
NEPFMCGO_01284	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEPFMCGO_01285	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEPFMCGO_01286	2.48e-105	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
NEPFMCGO_01289	2.51e-239	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NEPFMCGO_01290	4.42e-238	-	-	-	K	-	-	-	Periplasmic binding protein domain
NEPFMCGO_01291	4.2e-287	-	-	-	I	-	-	-	Serine aminopeptidase, S33
NEPFMCGO_01292	9.05e-12	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NEPFMCGO_01293	2.87e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
NEPFMCGO_01294	2.73e-19	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
NEPFMCGO_01295	1.22e-22	-	-	-	K	-	-	-	Helix-turn-helix domain
NEPFMCGO_01297	1.75e-06	-	-	-	M	-	-	-	PA domain
NEPFMCGO_01298	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NEPFMCGO_01299	1.27e-159	gntR	-	-	K	-	-	-	FCD
NEPFMCGO_01300	9.15e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEPFMCGO_01301	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
NEPFMCGO_01302	5.83e-291	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NEPFMCGO_01303	3.08e-211	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NEPFMCGO_01304	6.09e-152	safC	-	-	S	-	-	-	O-methyltransferase
NEPFMCGO_01305	1.19e-233	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NEPFMCGO_01306	3.17e-93	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
NEPFMCGO_01307	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
NEPFMCGO_01308	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
NEPFMCGO_01309	1.16e-75	-	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
NEPFMCGO_01310	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
NEPFMCGO_01311	7e-210	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NEPFMCGO_01312	8.11e-201	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NEPFMCGO_01313	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
NEPFMCGO_01314	1.8e-135	-	-	-	-	-	-	-	-
NEPFMCGO_01315	8.16e-179	-	-	-	-	-	-	-	-
NEPFMCGO_01316	2.47e-31	-	-	-	-	-	-	-	-
NEPFMCGO_01317	8.48e-215	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_01318	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NEPFMCGO_01319	0.0	-	-	-	I	-	-	-	PAP2 superfamily
NEPFMCGO_01320	1.69e-170	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NEPFMCGO_01321	0.0	-	-	-	T	-	-	-	Histidine kinase
NEPFMCGO_01322	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
NEPFMCGO_01323	1.17e-180	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEPFMCGO_01324	5.96e-213	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
NEPFMCGO_01325	1.56e-188	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NEPFMCGO_01326	3.83e-239	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NEPFMCGO_01327	1.1e-235	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
NEPFMCGO_01328	9.77e-259	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEPFMCGO_01329	9.77e-123	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01330	1.73e-290	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NEPFMCGO_01331	7.17e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEPFMCGO_01332	3.39e-210	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NEPFMCGO_01333	4.76e-153	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
NEPFMCGO_01334	2.1e-92	-	-	-	S	-	-	-	competence protein
NEPFMCGO_01335	2.49e-11	-	-	-	-	-	-	-	-
NEPFMCGO_01338	5.75e-10	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01339	1.3e-160	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01340	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
NEPFMCGO_01341	3.02e-199	-	-	-	J	-	-	-	Methyltransferase domain
NEPFMCGO_01342	7.28e-95	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
NEPFMCGO_01343	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NEPFMCGO_01344	6.04e-103	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NEPFMCGO_01346	1.52e-231	-	-	-	-	-	-	-	-
NEPFMCGO_01347	5.45e-31	-	-	-	-	-	-	-	-
NEPFMCGO_01348	1.43e-260	-	-	-	S	-	-	-	Short C-terminal domain
NEPFMCGO_01349	8.65e-110	-	-	-	S	-	-	-	Helix-turn-helix
NEPFMCGO_01350	4.07e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NEPFMCGO_01352	1.66e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NEPFMCGO_01353	8.69e-46	-	-	-	-	-	-	-	-
NEPFMCGO_01354	8.69e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NEPFMCGO_01355	5.26e-161	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NEPFMCGO_01356	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
NEPFMCGO_01357	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEPFMCGO_01358	2.07e-149	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
NEPFMCGO_01359	1.05e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NEPFMCGO_01360	2.14e-238	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NEPFMCGO_01361	4.05e-78	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NEPFMCGO_01362	4.04e-203	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NEPFMCGO_01363	2.75e-304	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
NEPFMCGO_01365	1.36e-68	-	-	-	-	-	-	-	-
NEPFMCGO_01366	1.88e-43	-	-	-	M	-	-	-	F5/8 type C domain
NEPFMCGO_01367	2.7e-259	-	-	-	C	-	-	-	Aldo/keto reductase family
NEPFMCGO_01368	8.38e-120	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEPFMCGO_01369	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_01370	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NEPFMCGO_01371	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
NEPFMCGO_01372	3.03e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NEPFMCGO_01373	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NEPFMCGO_01374	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
NEPFMCGO_01375	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
NEPFMCGO_01376	4.04e-127	-	-	-	S	-	-	-	GtrA-like protein
NEPFMCGO_01377	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEPFMCGO_01378	1.11e-161	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NEPFMCGO_01379	1.83e-192	-	-	-	-	-	-	-	-
NEPFMCGO_01381	9.66e-177	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01382	4.15e-257	-	-	-	P	-	-	-	NMT1/THI5 like
NEPFMCGO_01383	4.53e-157	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NEPFMCGO_01385	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEPFMCGO_01388	4.17e-315	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NEPFMCGO_01389	9.2e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
NEPFMCGO_01390	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEPFMCGO_01391	1.11e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEPFMCGO_01392	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01394	1.59e-247	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NEPFMCGO_01395	8.72e-280	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
NEPFMCGO_01396	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEPFMCGO_01397	2.62e-286	-	-	-	G	-	-	-	Transmembrane secretion effector
NEPFMCGO_01398	4.65e-167	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEPFMCGO_01399	3.16e-177	-	-	-	-	-	-	-	-
NEPFMCGO_01400	4.81e-94	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEPFMCGO_01401	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEPFMCGO_01403	2.19e-223	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
NEPFMCGO_01404	8.46e-242	-	-	-	-	-	-	-	-
NEPFMCGO_01405	4.83e-231	-	-	-	-	-	-	-	-
NEPFMCGO_01406	6.64e-212	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
NEPFMCGO_01407	1.58e-151	-	-	-	S	-	-	-	CYTH
NEPFMCGO_01409	4.87e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
NEPFMCGO_01410	2.44e-25	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
NEPFMCGO_01411	2.41e-123	-	-	-	L	-	-	-	Helix-turn-helix domain
NEPFMCGO_01412	3.84e-64	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NEPFMCGO_01413	2.69e-40	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
NEPFMCGO_01414	6.98e-31	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NEPFMCGO_01415	1.02e-54	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NEPFMCGO_01416	2.03e-243	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEPFMCGO_01417	1.22e-157	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01418	8.36e-158	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
NEPFMCGO_01419	6.21e-06	-	-	-	-	-	-	-	-
NEPFMCGO_01420	1.71e-228	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NEPFMCGO_01424	1.49e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
NEPFMCGO_01425	3.31e-194	-	-	-	L	ko:K07454	-	ko00000	HNH endonuclease
NEPFMCGO_01426	4.61e-222	-	-	-	-	-	-	-	-
NEPFMCGO_01427	2.77e-94	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
NEPFMCGO_01428	1.11e-148	-	-	-	K	-	-	-	WHG domain
NEPFMCGO_01429	1.57e-26	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
NEPFMCGO_01430	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEPFMCGO_01431	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01432	0.0	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NEPFMCGO_01435	1.63e-99	-	-	-	L	ko:K07485	-	ko00000	Transposase
NEPFMCGO_01436	7.13e-56	-	-	-	O	-	-	-	Glutaredoxin
NEPFMCGO_01437	1.24e-197	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
NEPFMCGO_01438	3.95e-127	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
NEPFMCGO_01439	1.52e-49	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEPFMCGO_01440	2.23e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEPFMCGO_01441	1.81e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEPFMCGO_01442	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NEPFMCGO_01443	4.31e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NEPFMCGO_01444	2.88e-131	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NEPFMCGO_01445	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
NEPFMCGO_01446	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01447	2.71e-233	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
NEPFMCGO_01448	2.06e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEPFMCGO_01449	6.15e-261	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEPFMCGO_01450	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NEPFMCGO_01451	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
NEPFMCGO_01452	2.58e-98	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
NEPFMCGO_01453	3.92e-247	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NEPFMCGO_01454	3.43e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEPFMCGO_01455	5.91e-209	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEPFMCGO_01456	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEPFMCGO_01457	7.24e-252	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NEPFMCGO_01458	3.29e-315	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NEPFMCGO_01459	1.42e-74	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NEPFMCGO_01461	7.82e-65	-	-	-	E	-	-	-	IrrE N-terminal-like domain
NEPFMCGO_01462	1.96e-83	-	-	-	-	-	-	-	-
NEPFMCGO_01463	4.37e-80	-	-	-	-	-	-	-	-
NEPFMCGO_01465	9.9e-116	XK26_06155	-	-	K	-	-	-	Psort location Cytoplasmic, score
NEPFMCGO_01466	0.0	-	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
NEPFMCGO_01467	4.04e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01468	2.74e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
NEPFMCGO_01469	1.66e-52	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
NEPFMCGO_01470	9.43e-21	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
NEPFMCGO_01471	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NEPFMCGO_01473	1.61e-221	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NEPFMCGO_01474	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
NEPFMCGO_01475	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NEPFMCGO_01476	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
NEPFMCGO_01477	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEPFMCGO_01478	6.39e-137	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NEPFMCGO_01479	5.21e-66	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NEPFMCGO_01481	4.83e-202	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
NEPFMCGO_01482	3.27e-67	-	-	-	S	-	-	-	Eco47II restriction endonuclease
NEPFMCGO_01483	7.56e-74	-	-	-	L	-	-	-	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
NEPFMCGO_01484	4.72e-296	-	-	-	L	-	-	-	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
NEPFMCGO_01485	4.04e-96	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NEPFMCGO_01486	3.14e-283	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
NEPFMCGO_01487	6.85e-109	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NEPFMCGO_01488	3.95e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
NEPFMCGO_01489	2.04e-28	-	-	-	S	-	-	-	Cysteine-rich KTR
NEPFMCGO_01490	2.53e-75	-	-	-	K	-	-	-	Sigma-70, region 4
NEPFMCGO_01491	3.29e-31	-	-	-	S	-	-	-	Helix-turn-helix domain
NEPFMCGO_01492	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01494	7.69e-11	-	-	-	D	ko:K03466	-	ko00000,ko03036	ftsk spoiiie
NEPFMCGO_01497	0.000121	xerC	-	-	D	ko:K03733	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids
NEPFMCGO_01503	0.000243	-	-	-	TV	ko:K05792	-	ko00000	HNH endonuclease
NEPFMCGO_01504	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NEPFMCGO_01506	6.17e-41	-	-	-	K	-	-	-	Transcriptional regulator
NEPFMCGO_01510	2.78e-294	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01511	8.28e-178	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01512	1.32e-66	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01513	6.9e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEPFMCGO_01514	5.74e-167	-	-	-	M	-	-	-	Mechanosensitive ion channel
NEPFMCGO_01515	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEPFMCGO_01517	2.33e-198	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
NEPFMCGO_01518	6.29e-140	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
NEPFMCGO_01519	2.08e-267	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NEPFMCGO_01520	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
NEPFMCGO_01521	0.0	-	-	-	M	-	-	-	domain protein
NEPFMCGO_01522	2.45e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
NEPFMCGO_01523	8.33e-189	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NEPFMCGO_01524	2.85e-235	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NEPFMCGO_01525	1.82e-174	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
NEPFMCGO_01526	3.99e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NEPFMCGO_01529	1.19e-90	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
NEPFMCGO_01531	2.34e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NEPFMCGO_01532	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEPFMCGO_01533	7.91e-111	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
NEPFMCGO_01534	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NEPFMCGO_01535	1.18e-235	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
NEPFMCGO_01536	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NEPFMCGO_01537	1.29e-258	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEPFMCGO_01538	1.27e-274	-	-	-	G	-	-	-	Transmembrane secretion effector
NEPFMCGO_01539	4.94e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEPFMCGO_01540	7.74e-17	-	-	-	-	-	-	-	-
NEPFMCGO_01541	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NEPFMCGO_01542	1.73e-57	-	-	-	L	-	-	-	Integrase core domain
NEPFMCGO_01543	1.51e-83	istB	-	-	L	-	-	-	IstB-like ATP binding protein
NEPFMCGO_01545	1.6e-43	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_01546	1.12e-95	-	-	-	I	-	-	-	Sterol carrier protein
NEPFMCGO_01547	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEPFMCGO_01548	7.68e-47	-	-	-	-	-	-	-	-
NEPFMCGO_01549	2.4e-186	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
NEPFMCGO_01550	3.09e-150	-	-	-	L	-	-	-	HTH-like domain
NEPFMCGO_01551	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
NEPFMCGO_01552	1.23e-90	crgA	-	-	D	-	-	-	Involved in cell division
NEPFMCGO_01553	1.38e-181	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NEPFMCGO_01554	9.36e-295	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NEPFMCGO_01555	3.71e-153	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
NEPFMCGO_01556	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NEPFMCGO_01557	5.69e-234	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NEPFMCGO_01558	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
NEPFMCGO_01559	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NEPFMCGO_01560	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
NEPFMCGO_01561	1.44e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
NEPFMCGO_01562	3.69e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
NEPFMCGO_01563	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
NEPFMCGO_01564	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NEPFMCGO_01565	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NEPFMCGO_01566	1.91e-260	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
NEPFMCGO_01567	9.28e-216	-	-	-	EG	-	-	-	EamA-like transporter family
NEPFMCGO_01568	1.35e-146	-	-	-	-	-	-	-	-
NEPFMCGO_01570	4.1e-251	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEPFMCGO_01572	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
NEPFMCGO_01573	4.31e-112	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NEPFMCGO_01574	1.65e-52	-	-	-	D	-	-	-	DivIVA domain protein
NEPFMCGO_01575	1.75e-69	-	-	-	S	-	-	-	Putative heavy-metal-binding
NEPFMCGO_01576	2.16e-199	-	-	-	I	-	-	-	Serine aminopeptidase, S33
NEPFMCGO_01577	2.72e-111	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
NEPFMCGO_01578	1.42e-60	-	-	-	-	-	-	-	-
NEPFMCGO_01579	3.38e-90	nfrA	-	-	C	-	-	-	Nitroreductase family
NEPFMCGO_01580	1.18e-67	nfrA	-	-	C	-	-	-	Nitroreductase family
NEPFMCGO_01581	4.98e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
NEPFMCGO_01582	1.84e-180	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
NEPFMCGO_01585	1.07e-240	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NEPFMCGO_01586	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
NEPFMCGO_01587	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NEPFMCGO_01588	3.29e-80	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEPFMCGO_01589	1.51e-233	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
NEPFMCGO_01590	6.42e-112	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
NEPFMCGO_01591	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
NEPFMCGO_01592	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat
NEPFMCGO_01593	1.17e-171	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NEPFMCGO_01595	1.82e-162	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NEPFMCGO_01596	2.67e-220	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEPFMCGO_01597	1.6e-83	-	-	-	-	-	-	-	-
NEPFMCGO_01598	7.68e-170	-	-	-	-	-	-	-	-
NEPFMCGO_01599	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEPFMCGO_01600	1.65e-108	-	-	-	K	-	-	-	Transcriptional regulator
NEPFMCGO_01601	3.95e-09	-	-	-	G	ko:K02027,ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEPFMCGO_01602	9.81e-33	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NEPFMCGO_01603	8.79e-48	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NEPFMCGO_01604	5.93e-140	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NEPFMCGO_01605	1.06e-234	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
NEPFMCGO_01606	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NEPFMCGO_01610	1.17e-211	-	-	-	S	-	-	-	Glutamine amidotransferase domain
NEPFMCGO_01611	1.98e-177	-	-	-	T	ko:K06950	-	ko00000	HD domain
NEPFMCGO_01612	2.59e-259	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NEPFMCGO_01613	0.0	-	-	-	V	-	-	-	ABC transporter permease
NEPFMCGO_01614	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
NEPFMCGO_01615	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01616	3.89e-211	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NEPFMCGO_01617	2.41e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
NEPFMCGO_01618	5.26e-267	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
NEPFMCGO_01619	1.28e-173	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
NEPFMCGO_01620	2.21e-81	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
NEPFMCGO_01621	1.03e-225	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NEPFMCGO_01622	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NEPFMCGO_01623	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEPFMCGO_01624	4.88e-106	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEPFMCGO_01625	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NEPFMCGO_01626	1.79e-304	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NEPFMCGO_01627	1.58e-238	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEPFMCGO_01628	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
NEPFMCGO_01629	5.09e-207	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_01630	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
NEPFMCGO_01631	4.53e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NEPFMCGO_01632	1.3e-300	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
NEPFMCGO_01633	6.44e-14	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
NEPFMCGO_01634	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
NEPFMCGO_01635	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NEPFMCGO_01636	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
NEPFMCGO_01637	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEPFMCGO_01638	2.13e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEPFMCGO_01639	1.6e-291	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
NEPFMCGO_01641	1e-43	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEPFMCGO_01642	7.67e-172	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NEPFMCGO_01643	1.27e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NEPFMCGO_01644	1.13e-226	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NEPFMCGO_01645	8.22e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NEPFMCGO_01646	2.12e-253	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NEPFMCGO_01647	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
NEPFMCGO_01648	3.09e-243	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEPFMCGO_01649	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NEPFMCGO_01650	2.7e-36	-	-	-	-	-	-	-	-
NEPFMCGO_01651	6.24e-176	-	-	-	L	-	-	-	IstB-like ATP binding protein
NEPFMCGO_01653	1.53e-52	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NEPFMCGO_01656	5.14e-57	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEPFMCGO_01657	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
NEPFMCGO_01659	1.37e-08	-	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
NEPFMCGO_01660	7.2e-91	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NEPFMCGO_01661	4.36e-22	-	-	-	FG	-	-	-	bis(5'-adenosyl)-triphosphatase activity
NEPFMCGO_01662	1.27e-28	-	-	-	FG	-	-	-	HIT domain
NEPFMCGO_01663	1.28e-225	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Glucuronate isomerase
NEPFMCGO_01664	1.54e-244	mtlD	1.1.1.57, 1.1.1.58	-	G	ko:K00040,ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
NEPFMCGO_01665	3.74e-294	-	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mandelate racemase muconate lactonizing
NEPFMCGO_01666	1.72e-82	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
NEPFMCGO_01667	1.2e-293	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEPFMCGO_01668	5.02e-218	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NEPFMCGO_01669	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
NEPFMCGO_01670	6.77e-46	-	-	-	-	-	-	-	-
NEPFMCGO_01671	1.83e-165	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01672	8.38e-170	-	-	-	U	ko:K02025,ko:K17242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01673	4.82e-201	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEPFMCGO_01674	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
NEPFMCGO_01675	5.64e-305	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
NEPFMCGO_01676	1.23e-229	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEPFMCGO_01677	2.84e-144	-	-	-	K	-	-	-	helix_turn_helix, Deoxyribose operon repressor
NEPFMCGO_01678	4.89e-74	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEPFMCGO_01679	1.06e-16	-	-	-	-	-	-	-	-
NEPFMCGO_01681	3.43e-182	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
NEPFMCGO_01682	3.72e-80	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NEPFMCGO_01683	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
NEPFMCGO_01684	1.24e-68	-	-	-	-	-	-	-	-
NEPFMCGO_01685	0.0	-	-	-	K	-	-	-	WYL domain
NEPFMCGO_01686	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NEPFMCGO_01688	6.27e-165	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
NEPFMCGO_01689	1.69e-228	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NEPFMCGO_01690	1.5e-276	-	-	-	GK	-	-	-	ROK family
NEPFMCGO_01691	1.41e-263	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
NEPFMCGO_01692	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NEPFMCGO_01693	6.83e-253	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NEPFMCGO_01694	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NEPFMCGO_01695	3.28e-178	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NEPFMCGO_01696	1.19e-312	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NEPFMCGO_01697	2.13e-151	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NEPFMCGO_01698	7.28e-76	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NEPFMCGO_01699	1.84e-113	-	-	-	-	-	-	-	-
NEPFMCGO_01700	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEPFMCGO_01701	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEPFMCGO_01702	4.13e-228	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
NEPFMCGO_01703	1.01e-225	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NEPFMCGO_01704	3.23e-222	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NEPFMCGO_01705	6.71e-284	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
NEPFMCGO_01706	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEPFMCGO_01707	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
NEPFMCGO_01708	2.9e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NEPFMCGO_01709	4.05e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NEPFMCGO_01710	1.74e-307	-	-	-	V	-	-	-	MatE
NEPFMCGO_01711	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NEPFMCGO_01712	1.8e-181	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NEPFMCGO_01713	4.49e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NEPFMCGO_01714	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
NEPFMCGO_01715	8.07e-280	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEPFMCGO_01716	6.31e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEPFMCGO_01717	3.33e-203	-	-	-	G	-	-	-	Fructosamine kinase
NEPFMCGO_01718	8.18e-216	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEPFMCGO_01719	2.89e-199	-	-	-	S	-	-	-	PAC2 family
NEPFMCGO_01723	0.0	-	-	-	-	-	-	-	-
NEPFMCGO_01726	0.0	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEPFMCGO_01727	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEPFMCGO_01728	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
NEPFMCGO_01729	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
NEPFMCGO_01730	2.64e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NEPFMCGO_01732	2.14e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEPFMCGO_01733	5.68e-258	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEPFMCGO_01734	4.16e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
NEPFMCGO_01735	1.31e-129	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEPFMCGO_01736	6.71e-284	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NEPFMCGO_01737	7.82e-211	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NEPFMCGO_01738	5.02e-310	-	-	-	-	-	-	-	-
NEPFMCGO_01739	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NEPFMCGO_01740	5.17e-56	-	-	-	-	-	-	-	-
NEPFMCGO_01741	4.45e-163	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NEPFMCGO_01742	9.44e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NEPFMCGO_01743	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NEPFMCGO_01744	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEPFMCGO_01745	1.53e-208	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEPFMCGO_01746	3.18e-237	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEPFMCGO_01747	1.27e-143	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
NEPFMCGO_01748	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
NEPFMCGO_01749	3.56e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
NEPFMCGO_01750	4.49e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEPFMCGO_01751	1.13e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NEPFMCGO_01752	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
NEPFMCGO_01753	1.53e-179	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NEPFMCGO_01754	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
NEPFMCGO_01755	5.64e-153	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NEPFMCGO_01756	6.69e-81	-	-	-	-	-	-	-	-
NEPFMCGO_01758	4.2e-31	-	-	-	L	-	-	-	DNA integration
NEPFMCGO_01759	2.07e-160	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NEPFMCGO_01760	1.49e-117	-	-	-	K	-	-	-	Putative zinc ribbon domain
NEPFMCGO_01762	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_01763	1.62e-183	istB	-	-	L	-	-	-	IstB-like ATP binding protein
NEPFMCGO_01764	1.45e-234	-	-	GT2	M	ko:K13670	-	ko00000,ko01000	Glycosyltransferase like family 2
NEPFMCGO_01765	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NEPFMCGO_01766	1.35e-37	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NEPFMCGO_01767	8.71e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEPFMCGO_01768	8.13e-137	-	-	-	T	-	-	-	protein histidine kinase activity
NEPFMCGO_01769	3.31e-114	-	-	-	K	-	-	-	LytTr DNA-binding domain
NEPFMCGO_01770	8.99e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
NEPFMCGO_01771	3.29e-259	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NEPFMCGO_01772	1.94e-247	-	-	-	S	-	-	-	Protein conserved in bacteria
NEPFMCGO_01773	2.97e-225	-	-	-	S	-	-	-	Amidohydrolase family
NEPFMCGO_01774	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NEPFMCGO_01775	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NEPFMCGO_01776	1.95e-308	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NEPFMCGO_01777	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NEPFMCGO_01778	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
NEPFMCGO_01779	6.08e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NEPFMCGO_01780	7.67e-97	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NEPFMCGO_01781	3.36e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
NEPFMCGO_01782	1.03e-242	-	-	-	EG	-	-	-	EamA-like transporter family
NEPFMCGO_01783	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NEPFMCGO_01784	3.31e-172	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
NEPFMCGO_01785	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NEPFMCGO_01786	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NEPFMCGO_01787	8.85e-102	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEPFMCGO_01788	4.21e-243	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NEPFMCGO_01790	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
NEPFMCGO_01793	2.35e-84	-	-	-	-	-	-	-	-
NEPFMCGO_01794	1.25e-96	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEPFMCGO_01795	2.31e-163	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
NEPFMCGO_01796	1.28e-119	-	-	-	GK	-	-	-	ROK family
NEPFMCGO_01797	3.4e-126	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEPFMCGO_01798	1.2e-136	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01799	1.51e-119	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01800	2.6e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF4127)
NEPFMCGO_01801	1.65e-72	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NEPFMCGO_01802	3.23e-108	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NEPFMCGO_01805	4.78e-106	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
NEPFMCGO_01806	1.71e-116	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
NEPFMCGO_01808	4.26e-86	-	-	-	-	-	-	-	-
NEPFMCGO_01809	3.02e-76	-	-	-	S	-	-	-	pathogenesis
NEPFMCGO_01810	2.26e-45	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
NEPFMCGO_01811	1.69e-163	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
NEPFMCGO_01813	8.44e-108	-	-	-	E	-	-	-	Bacterial extracellular solute-binding proteins, family 5 Middle
NEPFMCGO_01814	2.55e-72	-	-	-	EP	-	-	-	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01815	1.15e-61	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEPFMCGO_01816	4.95e-68	-	-	-	EP	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_01817	1.4e-67	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NEPFMCGO_01818	1.24e-102	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NEPFMCGO_01819	2.02e-47	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEPFMCGO_01820	1.05e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
NEPFMCGO_01823	8.31e-310	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEPFMCGO_01824	7.66e-163	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEPFMCGO_01825	4.05e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEPFMCGO_01826	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NEPFMCGO_01827	6.3e-308	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEPFMCGO_01828	1.94e-316	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
NEPFMCGO_01829	6.01e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
NEPFMCGO_01830	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEPFMCGO_01831	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NEPFMCGO_01832	2.33e-53	-	-	-	-	-	-	-	-
NEPFMCGO_01833	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NEPFMCGO_01834	2.83e-285	-	-	-	S	-	-	-	Peptidase dimerisation domain
NEPFMCGO_01837	3.62e-32	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
NEPFMCGO_01838	9.61e-213	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NEPFMCGO_01839	6.9e-134	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEPFMCGO_01840	2.54e-96	-	-	-	-	-	-	-	-
NEPFMCGO_01842	3.68e-281	-	-	-	S	-	-	-	HipA-like C-terminal domain
NEPFMCGO_01843	1.88e-48	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
NEPFMCGO_01845	5.32e-36	-	-	-	-	-	-	-	-
NEPFMCGO_01846	6.64e-183	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NEPFMCGO_01847	1.19e-35	intA	-	-	L	-	-	-	Phage integrase family
NEPFMCGO_01849	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEPFMCGO_01850	1.68e-183	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NEPFMCGO_01851	2.76e-141	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NEPFMCGO_01852	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NEPFMCGO_01853	1.69e-218	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NEPFMCGO_01854	4.93e-54	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NEPFMCGO_01855	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
NEPFMCGO_01856	9.88e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEPFMCGO_01857	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NEPFMCGO_01858	5.67e-231	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEPFMCGO_01859	1.69e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NEPFMCGO_01860	1.68e-226	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NEPFMCGO_01861	2.89e-272	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEPFMCGO_01862	9.11e-261	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEPFMCGO_01863	2.48e-133	-	-	-	-	-	-	-	-
NEPFMCGO_01864	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
NEPFMCGO_01865	3.04e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEPFMCGO_01866	1.84e-204	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEPFMCGO_01867	8.29e-174	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEPFMCGO_01868	1.08e-174	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NEPFMCGO_01869	2.18e-11	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
NEPFMCGO_01871	6.51e-88	-	-	-	K	-	-	-	AraC-like ligand binding domain
NEPFMCGO_01872	5.58e-33	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
NEPFMCGO_01873	9.3e-53	-	-	-	-	-	-	-	-
NEPFMCGO_01874	1.71e-144	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
NEPFMCGO_01877	1.95e-49	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEPFMCGO_01879	2.04e-308	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
NEPFMCGO_01880	6.52e-139	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEPFMCGO_01881	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NEPFMCGO_01882	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NEPFMCGO_01883	2.02e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
NEPFMCGO_01884	5.36e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NEPFMCGO_01885	1.29e-170	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NEPFMCGO_01886	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEPFMCGO_01887	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NEPFMCGO_01888	8.18e-305	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPFMCGO_01889	2.32e-197	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NEPFMCGO_01890	3.56e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEPFMCGO_01891	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NEPFMCGO_01892	1.61e-220	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NEPFMCGO_01893	1.57e-50	-	-	-	L	-	-	-	Transposase
NEPFMCGO_01894	2.49e-14	-	-	-	L	ko:K07485	-	ko00000	Transposase
NEPFMCGO_01895	1.1e-31	-	-	-	-	-	-	-	-
NEPFMCGO_01896	1.85e-20	-	-	-	L	ko:K07483	-	ko00000	transposase activity
NEPFMCGO_01897	7.47e-25	-	-	-	L	ko:K07483	-	ko00000	transposase activity
NEPFMCGO_01898	2.62e-194	tnp3521a2	-	-	L	-	-	-	Integrase core domain
NEPFMCGO_01899	1.03e-137	-	-	-	-	-	-	-	-
NEPFMCGO_01900	3.94e-249	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEPFMCGO_01901	5.56e-89	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_01903	1.52e-227	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_01904	7.46e-114	istB	-	-	L	-	-	-	IstB-like ATP binding protein
NEPFMCGO_01905	1.5e-63	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_01906	8.88e-264	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_01907	3.02e-53	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_01908	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
NEPFMCGO_01909	0.0	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
NEPFMCGO_01910	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
NEPFMCGO_01911	3.48e-245	-	-	-	I	-	-	-	Acyltransferase family
NEPFMCGO_01912	5.05e-93	-	1.1.1.339	-	GM	ko:K19180	ko00523,ko01130,map00523,map01130	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
NEPFMCGO_01913	5.53e-162	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_01914	1.29e-110	istB	-	-	L	-	-	-	IstB-like ATP binding protein
NEPFMCGO_01916	6.97e-29	pinR	-	-	L	-	-	-	resolvase
NEPFMCGO_01917	2.33e-28	-	-	-	-	-	-	-	-
NEPFMCGO_01919	2.36e-71	-	-	-	-	-	-	-	-
NEPFMCGO_01920	7.68e-182	-	-	-	T	ko:K06919	-	ko00000	regulation of circadian rhythm
NEPFMCGO_01921	1.65e-269	-	-	-	T	-	-	-	AAA domain
NEPFMCGO_01922	0.0	-	-	-	S	-	-	-	FRG domain
NEPFMCGO_01923	3.23e-291	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NEPFMCGO_01924	1.61e-222	-	-	-	S	-	-	-	Domain of unknown function (DUF4928)
NEPFMCGO_01925	2.04e-153	vpr	-	-	O	-	-	-	Subtilase family
NEPFMCGO_01926	7.41e-125	vpr	-	-	O	-	-	-	Subtilase family
NEPFMCGO_01928	1.23e-264	-	-	-	K	-	-	-	Transposase IS116 IS110 IS902
NEPFMCGO_01929	6.18e-287	-	-	-	L	-	-	-	PFAM Integrase catalytic
NEPFMCGO_01930	2.94e-259	-	-	-	L	-	-	-	Transposase, Mutator family
NEPFMCGO_01931	8.53e-230	-	-	-	L	-	-	-	Transposase, Mutator family