Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PNFEGDNE_00001	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PNFEGDNE_00002	1.81e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PNFEGDNE_00003	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
PNFEGDNE_00004	2.79e-192	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PNFEGDNE_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PNFEGDNE_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PNFEGDNE_00007	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PNFEGDNE_00008	6.48e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PNFEGDNE_00009	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PNFEGDNE_00010	5.79e-138	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
PNFEGDNE_00011	6.63e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
PNFEGDNE_00012	3.2e-81	-	-	-	D	-	-	-	peptidase
PNFEGDNE_00013	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PNFEGDNE_00014	5.27e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PNFEGDNE_00015	8.71e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PNFEGDNE_00016	3.25e-307	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PNFEGDNE_00017	5.01e-22	yneR	-	-	-	-	-	-	-
PNFEGDNE_00018	2.06e-289	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PNFEGDNE_00019	4.36e-283	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PNFEGDNE_00020	3.32e-136	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PNFEGDNE_00021	2.59e-192	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PNFEGDNE_00022	8.18e-11	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNFEGDNE_00023	1.27e-140	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PNFEGDNE_00024	1.86e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
PNFEGDNE_00025	2.09e-88	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PNFEGDNE_00026	2.33e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
PNFEGDNE_00027	1.82e-08	pepF	-	-	E	-	-	-	oligoendopeptidase F
PNFEGDNE_00029	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_00030	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_00031	1.26e-244	pepF	-	-	E	-	-	-	Oligopeptidase F
PNFEGDNE_00032	4.43e-137	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PNFEGDNE_00033	5.74e-224	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PNFEGDNE_00034	1.54e-173	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
PNFEGDNE_00035	2.04e-76	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K07305,ko:K12267	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PNFEGDNE_00036	3.06e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PNFEGDNE_00037	2.96e-40	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
PNFEGDNE_00038	6.45e-218	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PNFEGDNE_00039	6.63e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PNFEGDNE_00040	1.32e-270	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_00041	1.56e-302	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
PNFEGDNE_00042	4.57e-13	yxeH	-	-	S	-	-	-	hydrolase
PNFEGDNE_00043	5.21e-108	yxeH	-	-	S	-	-	-	hydrolase
PNFEGDNE_00044	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PNFEGDNE_00045	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PNFEGDNE_00046	7.57e-126	yycH	-	-	S	-	-	-	YycH protein
PNFEGDNE_00047	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
PNFEGDNE_00048	1.37e-40	-	-	-	S	-	-	-	YjbR
PNFEGDNE_00049	6.9e-146	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PNFEGDNE_00050	8.15e-188	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PNFEGDNE_00051	7.88e-94	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PNFEGDNE_00052	7.57e-52	-	-	-	GM	-	-	-	NAD(P)H-binding
PNFEGDNE_00053	3.67e-34	-	-	-	K	-	-	-	MarR family transcriptional regulator
PNFEGDNE_00054	3.84e-112	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PNFEGDNE_00055	1.3e-30	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PNFEGDNE_00057	9.23e-261	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
PNFEGDNE_00058	1.92e-171	-	-	-	S	-	-	-	interspecies interaction between organisms
PNFEGDNE_00059	2.49e-46	ebh	-	-	D	-	-	-	interspecies interaction between organisms
PNFEGDNE_00060	3.42e-104	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PNFEGDNE_00061	1.77e-183	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PNFEGDNE_00062	5.41e-188	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PNFEGDNE_00063	1.2e-105	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PNFEGDNE_00064	1.5e-141	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PNFEGDNE_00065	7.58e-252	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PNFEGDNE_00066	2.65e-35	-	-	-	-	-	-	-	-
PNFEGDNE_00067	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
PNFEGDNE_00068	4.99e-78	-	-	-	T	-	-	-	Universal stress protein family
PNFEGDNE_00070	3.82e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNFEGDNE_00071	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PNFEGDNE_00072	1.88e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PNFEGDNE_00073	1.91e-271	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PNFEGDNE_00074	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PNFEGDNE_00075	2.24e-228	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PNFEGDNE_00076	8.44e-145	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
PNFEGDNE_00077	1.08e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
PNFEGDNE_00078	7.12e-68	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PNFEGDNE_00079	3.6e-56	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
PNFEGDNE_00080	3.9e-150	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNFEGDNE_00081	1.03e-127	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PNFEGDNE_00082	6.65e-27	-	-	-	-	-	-	-	-
PNFEGDNE_00083	1.92e-73	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PNFEGDNE_00084	3.77e-180	-	-	-	G	-	-	-	PFAM major facilitator superfamily MFS_1
PNFEGDNE_00085	1.48e-129	gbpD	-	-	S	-	-	-	Phospholipase/Carboxylesterase
PNFEGDNE_00086	3.52e-97	-	-	-	GK	-	-	-	ROK family
PNFEGDNE_00087	2.19e-310	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PNFEGDNE_00088	9.86e-63	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PNFEGDNE_00089	1.19e-08	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PNFEGDNE_00090	3.19e-20	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PNFEGDNE_00091	2.69e-71	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PNFEGDNE_00092	1.16e-226	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PNFEGDNE_00093	4.32e-115	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PNFEGDNE_00094	1.6e-91	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PNFEGDNE_00095	2.35e-76	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PNFEGDNE_00096	2.03e-50	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PNFEGDNE_00097	4.36e-50	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PNFEGDNE_00098	1.41e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PNFEGDNE_00099	2.49e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PNFEGDNE_00100	4.42e-50	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNFEGDNE_00101	1.22e-89	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
PNFEGDNE_00102	5.94e-148	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PNFEGDNE_00103	1.51e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
PNFEGDNE_00104	2.08e-52	baeS	-	-	T	-	-	-	Histidine kinase
PNFEGDNE_00105	2.76e-46	baeS	-	-	T	-	-	-	Histidine kinase
PNFEGDNE_00106	1.16e-103	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
PNFEGDNE_00107	3.19e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PNFEGDNE_00108	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PNFEGDNE_00109	8.07e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PNFEGDNE_00110	1.61e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
PNFEGDNE_00111	1.09e-90	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PNFEGDNE_00112	2.89e-164	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PNFEGDNE_00113	1.49e-207	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNFEGDNE_00114	9.54e-97	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
PNFEGDNE_00115	3.61e-43	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
PNFEGDNE_00116	4.2e-309	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PNFEGDNE_00117	2.91e-74	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PNFEGDNE_00118	6.32e-136	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PNFEGDNE_00119	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PNFEGDNE_00120	3.37e-40	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
PNFEGDNE_00121	1.77e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
PNFEGDNE_00122	1.43e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
PNFEGDNE_00123	5.5e-08	-	-	-	S	-	-	-	Putative adhesin
PNFEGDNE_00124	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
PNFEGDNE_00126	4.13e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PNFEGDNE_00127	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
PNFEGDNE_00128	3.27e-130	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PNFEGDNE_00129	1.56e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PNFEGDNE_00130	3.85e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNFEGDNE_00131	3.11e-133	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PNFEGDNE_00132	1.19e-201	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNFEGDNE_00133	7.9e-169	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PNFEGDNE_00134	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PNFEGDNE_00135	1.41e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_00136	3.36e-85	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PNFEGDNE_00137	9.35e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PNFEGDNE_00138	3.04e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PNFEGDNE_00139	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PNFEGDNE_00140	2.22e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
PNFEGDNE_00141	4.49e-72	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PNFEGDNE_00142	5.18e-61	-	-	-	C	-	-	-	Flavodoxin
PNFEGDNE_00143	2.05e-76	yphH	-	-	S	-	-	-	Cupin domain
PNFEGDNE_00144	3.55e-11	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
PNFEGDNE_00145	1.9e-38	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
PNFEGDNE_00146	3.1e-178	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PNFEGDNE_00147	4.23e-135	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PNFEGDNE_00148	1.87e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PNFEGDNE_00149	5.23e-119	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNFEGDNE_00150	2.27e-168	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PNFEGDNE_00151	2.84e-107	-	-	-	C	-	-	-	nitroreductase
PNFEGDNE_00152	3.08e-106	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
PNFEGDNE_00153	2.87e-137	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
PNFEGDNE_00154	1.74e-213	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PNFEGDNE_00155	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
PNFEGDNE_00157	3.6e-191	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PNFEGDNE_00158	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNFEGDNE_00159	3.63e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PNFEGDNE_00160	1.39e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
PNFEGDNE_00162	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PNFEGDNE_00163	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PNFEGDNE_00164	7.47e-213	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
PNFEGDNE_00165	3.16e-229	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PNFEGDNE_00166	4.36e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
PNFEGDNE_00167	9.52e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PNFEGDNE_00168	2.63e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PNFEGDNE_00169	1.74e-79	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PNFEGDNE_00170	1.78e-17	-	-	-	-	-	-	-	-
PNFEGDNE_00171	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PNFEGDNE_00172	5.62e-281	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PNFEGDNE_00173	8e-111	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
PNFEGDNE_00174	2.72e-191	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PNFEGDNE_00175	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PNFEGDNE_00176	2.33e-57	cps3F	-	-	-	-	-	-	-
PNFEGDNE_00177	3.15e-108	-	-	-	S	-	-	-	Membrane
PNFEGDNE_00178	0.0	-	-	-	E	-	-	-	Amino acid permease
PNFEGDNE_00179	1.75e-204	cadA	-	-	P	-	-	-	P-type ATPase
PNFEGDNE_00180	3.69e-71	cadA	-	-	P	-	-	-	P-type ATPase
PNFEGDNE_00181	2.47e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
PNFEGDNE_00182	2.05e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PNFEGDNE_00183	6.11e-69	-	-	-	F	-	-	-	glutamine amidotransferase
PNFEGDNE_00184	1.86e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
PNFEGDNE_00185	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PNFEGDNE_00186	2.1e-171	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PNFEGDNE_00187	6.81e-103	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
PNFEGDNE_00188	1.18e-207	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
PNFEGDNE_00189	2e-19	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PNFEGDNE_00190	2.2e-286	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PNFEGDNE_00191	3.41e-159	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PNFEGDNE_00192	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
PNFEGDNE_00193	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PNFEGDNE_00194	2.71e-106	lysR5	-	-	K	-	-	-	LysR substrate binding domain
PNFEGDNE_00195	5.31e-72	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
PNFEGDNE_00196	2.9e-14	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PNFEGDNE_00197	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PNFEGDNE_00198	7.88e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
PNFEGDNE_00199	7.55e-308	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
PNFEGDNE_00200	7.95e-263	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PNFEGDNE_00212	4.84e-166	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PNFEGDNE_00213	1.32e-235	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PNFEGDNE_00214	1.59e-198	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PNFEGDNE_00215	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PNFEGDNE_00216	1.5e-152	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PNFEGDNE_00218	1.98e-72	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PNFEGDNE_00219	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PNFEGDNE_00220	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNFEGDNE_00221	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNFEGDNE_00222	4.42e-29	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
PNFEGDNE_00223	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PNFEGDNE_00224	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PNFEGDNE_00225	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PNFEGDNE_00226	2.69e-116	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PNFEGDNE_00227	2.23e-105	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PNFEGDNE_00228	1.21e-145	vanR	-	-	K	-	-	-	response regulator
PNFEGDNE_00229	3.05e-190	hpk31	-	-	T	-	-	-	Histidine kinase
PNFEGDNE_00230	3.59e-114	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PNFEGDNE_00231	5.55e-188	-	-	-	G	-	-	-	Transporter, major facilitator family protein
PNFEGDNE_00232	9.53e-279	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PNFEGDNE_00233	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_00234	4.44e-44	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNFEGDNE_00235	9.3e-280	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_00236	6.78e-317	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PNFEGDNE_00237	1.29e-11	-	-	-	-	-	-	-	-
PNFEGDNE_00238	1.24e-57	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
PNFEGDNE_00239	1.2e-67	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
PNFEGDNE_00240	3.17e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PNFEGDNE_00241	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PNFEGDNE_00243	1.65e-292	-	-	-	L	-	-	-	DNA helicase
PNFEGDNE_00244	1.94e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PNFEGDNE_00245	1.63e-216	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PNFEGDNE_00246	1.13e-128	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PNFEGDNE_00247	1.58e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
PNFEGDNE_00248	1.28e-130	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PNFEGDNE_00249	1.91e-40	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNFEGDNE_00250	7.47e-55	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
PNFEGDNE_00251	3.08e-190	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PNFEGDNE_00252	4.8e-164	-	-	-	-	-	-	-	-
PNFEGDNE_00253	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PNFEGDNE_00254	3.62e-133	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PNFEGDNE_00255	1.7e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PNFEGDNE_00256	2.18e-168	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PNFEGDNE_00257	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PNFEGDNE_00258	1.1e-114	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PNFEGDNE_00259	5.51e-171	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
PNFEGDNE_00260	5.1e-62	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PNFEGDNE_00261	1.19e-146	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PNFEGDNE_00262	3.68e-194	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PNFEGDNE_00264	3.18e-252	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PNFEGDNE_00265	3.94e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PNFEGDNE_00266	5.76e-189	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PNFEGDNE_00267	1.16e-160	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNFEGDNE_00268	4.5e-135	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PNFEGDNE_00269	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PNFEGDNE_00270	1.26e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
PNFEGDNE_00271	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PNFEGDNE_00272	2.7e-71	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PNFEGDNE_00273	7.9e-257	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PNFEGDNE_00274	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PNFEGDNE_00275	2.48e-24	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PNFEGDNE_00276	5.54e-139	dkgB	-	-	S	-	-	-	reductase
PNFEGDNE_00277	1.82e-33	-	-	-	-	-	-	-	-
PNFEGDNE_00278	6.86e-100	-	-	-	F	-	-	-	Phosphorylase superfamily
PNFEGDNE_00279	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PNFEGDNE_00280	8.06e-78	ytkL	-	-	S	-	-	-	Beta-lactamase superfamily domain
PNFEGDNE_00281	7.07e-124	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PNFEGDNE_00282	5.24e-155	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PNFEGDNE_00283	6.71e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
PNFEGDNE_00285	3e-60	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
PNFEGDNE_00287	2.02e-25	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
PNFEGDNE_00289	1.69e-59	-	-	-	-	-	-	-	-
PNFEGDNE_00290	1.17e-22	-	-	-	-	-	-	-	-
PNFEGDNE_00291	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_00292	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_00294	4.25e-118	-	-	-	L	-	-	-	AAA ATPase domain
PNFEGDNE_00295	3.11e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
PNFEGDNE_00296	2.04e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
PNFEGDNE_00298	2.8e-175	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
PNFEGDNE_00300	2.79e-207	spoVK	-	-	O	ko:K06413	-	ko00000	PFAM ATPase family associated with various cellular activities (AAA)
PNFEGDNE_00301	4.19e-199	-	-	-	C	-	-	-	Oxidoreductase
PNFEGDNE_00302	3.59e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
PNFEGDNE_00303	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PNFEGDNE_00304	2.11e-122	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PNFEGDNE_00305	6e-76	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PNFEGDNE_00306	1.42e-221	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
PNFEGDNE_00307	4.82e-20	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
PNFEGDNE_00308	4.35e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PNFEGDNE_00309	6.84e-250	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PNFEGDNE_00310	1.8e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PNFEGDNE_00311	5.15e-41	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PNFEGDNE_00312	1.32e-204	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PNFEGDNE_00313	2.19e-59	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
PNFEGDNE_00314	2.77e-128	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PNFEGDNE_00316	4.99e-184	-	-	-	M	-	-	-	Rib/alpha-like repeat
PNFEGDNE_00317	3.62e-87	-	-	-	M	-	-	-	Rib/alpha-like repeat
PNFEGDNE_00318	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
PNFEGDNE_00319	2.68e-77	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
PNFEGDNE_00320	8.27e-53	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNFEGDNE_00321	3.65e-74	napB	-	-	K	-	-	-	transcriptional
PNFEGDNE_00322	7.97e-90	mleR	-	-	K	-	-	-	LysR family
PNFEGDNE_00323	2.92e-314	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PNFEGDNE_00324	2.15e-162	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
PNFEGDNE_00325	2.31e-81	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PNFEGDNE_00326	7.37e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PNFEGDNE_00327	5.57e-96	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PNFEGDNE_00328	1.56e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PNFEGDNE_00329	1.21e-45	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PNFEGDNE_00330	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PNFEGDNE_00331	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PNFEGDNE_00332	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PNFEGDNE_00333	1.3e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PNFEGDNE_00334	1.27e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
PNFEGDNE_00336	1.96e-54	-	-	-	-	-	-	-	-
PNFEGDNE_00337	1.32e-41	-	-	-	K	-	-	-	GNAT family
PNFEGDNE_00338	2.28e-262	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PNFEGDNE_00339	1.46e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
PNFEGDNE_00340	5.43e-46	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
PNFEGDNE_00341	1.09e-274	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PNFEGDNE_00342	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PNFEGDNE_00343	8.3e-210	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PNFEGDNE_00344	9.63e-158	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
PNFEGDNE_00345	7.4e-243	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
PNFEGDNE_00346	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PNFEGDNE_00347	4.58e-213	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PNFEGDNE_00348	7.99e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
PNFEGDNE_00349	1.08e-160	mocA	-	-	S	-	-	-	Oxidoreductase
PNFEGDNE_00350	1.39e-201	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PNFEGDNE_00353	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PNFEGDNE_00354	4.67e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
PNFEGDNE_00355	3.51e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
PNFEGDNE_00356	2.37e-96	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PNFEGDNE_00357	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PNFEGDNE_00358	1.5e-108	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PNFEGDNE_00359	0.0	-	-	-	E	-	-	-	Amino acid permease
PNFEGDNE_00360	1e-228	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
PNFEGDNE_00361	6.71e-214	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PNFEGDNE_00362	2.43e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
PNFEGDNE_00363	1.31e-154	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
PNFEGDNE_00364	1.97e-151	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
PNFEGDNE_00365	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
PNFEGDNE_00366	3.26e-68	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
PNFEGDNE_00367	2.04e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PNFEGDNE_00368	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PNFEGDNE_00369	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PNFEGDNE_00370	2.34e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
PNFEGDNE_00371	1.95e-118	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PNFEGDNE_00384	1.25e-273	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
PNFEGDNE_00385	1.18e-98	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNFEGDNE_00386	4.48e-60	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
PNFEGDNE_00387	5.61e-39	-	-	-	-	-	-	-	-
PNFEGDNE_00388	8.35e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
PNFEGDNE_00389	2.32e-37	-	-	-	E	-	-	-	Zn peptidase
PNFEGDNE_00390	5.02e-39	-	-	-	K	-	-	-	Helix-turn-helix domain
PNFEGDNE_00393	9.37e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNFEGDNE_00394	3.59e-136	-	-	-	K	-	-	-	ORF6N domain
PNFEGDNE_00399	4.62e-204	-	-	-	D	-	-	-	AAA domain
PNFEGDNE_00400	7.67e-131	-	-	-	S	-	-	-	AAA domain
PNFEGDNE_00401	1.89e-66	-	-	-	-	-	-	-	-
PNFEGDNE_00402	6.6e-52	-	-	-	-	-	-	-	-
PNFEGDNE_00403	2.61e-105	-	-	-	-	-	-	-	-
PNFEGDNE_00404	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PNFEGDNE_00405	0.0	-	-	-	L	-	-	-	Primase C terminal 2 (PriCT-2)
PNFEGDNE_00406	3.24e-58	-	-	-	S	-	-	-	magnesium ion binding
PNFEGDNE_00416	6.12e-27	-	-	-	-	-	-	-	-
PNFEGDNE_00417	1.45e-209	-	-	-	S	-	-	-	Pfam:Terminase_3C
PNFEGDNE_00418	7.9e-176	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
PNFEGDNE_00419	6.28e-117	-	-	-	S	-	-	-	Phage minor capsid protein 2
PNFEGDNE_00421	8.76e-19	-	-	-	S	-	-	-	YjcQ protein
PNFEGDNE_00422	3.73e-27	-	-	-	S	-	-	-	Phage minor structural protein GP20
PNFEGDNE_00423	3.12e-123	-	-	-	S	-	-	-	T=7 icosahedral viral capsid
PNFEGDNE_00425	1.39e-39	-	-	-	S	-	-	-	Minor capsid protein
PNFEGDNE_00428	9.49e-50	-	-	-	N	-	-	-	domain, Protein
PNFEGDNE_00430	1.44e-47	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
PNFEGDNE_00431	1.27e-111	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PNFEGDNE_00433	6.86e-72	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
PNFEGDNE_00435	6.82e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
PNFEGDNE_00440	6.09e-28	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
PNFEGDNE_00441	1.67e-145	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
PNFEGDNE_00442	1.53e-61	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PNFEGDNE_00443	1.87e-85	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PNFEGDNE_00444	5.02e-288	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PNFEGDNE_00445	1.01e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
PNFEGDNE_00446	1.07e-125	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PNFEGDNE_00447	2.58e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PNFEGDNE_00448	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PNFEGDNE_00449	7.48e-147	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PNFEGDNE_00450	7.85e-107	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PNFEGDNE_00451	1.84e-30	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PNFEGDNE_00452	1.12e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PNFEGDNE_00453	1.21e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PNFEGDNE_00454	8.01e-100	-	-	-	S	-	-	-	VIT family
PNFEGDNE_00455	2.71e-107	-	-	-	S	-	-	-	membrane
PNFEGDNE_00456	3.97e-53	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PNFEGDNE_00457	8.68e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PNFEGDNE_00458	3.39e-47	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PNFEGDNE_00459	3.43e-96	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PNFEGDNE_00461	2.23e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PNFEGDNE_00463	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PNFEGDNE_00464	1.26e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PNFEGDNE_00465	4.81e-54	-	-	-	S	-	-	-	VanZ like family
PNFEGDNE_00466	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PNFEGDNE_00467	8.16e-130	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PNFEGDNE_00468	2.24e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PNFEGDNE_00469	7.88e-122	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PNFEGDNE_00470	4.34e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
PNFEGDNE_00471	7.13e-18	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
PNFEGDNE_00475	1.41e-123	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PNFEGDNE_00476	1.22e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PNFEGDNE_00477	9.2e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PNFEGDNE_00478	4.29e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PNFEGDNE_00479	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PNFEGDNE_00480	1.14e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PNFEGDNE_00481	1.08e-117	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
PNFEGDNE_00482	4.05e-119	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PNFEGDNE_00483	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
PNFEGDNE_00503	5.21e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PNFEGDNE_00504	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PNFEGDNE_00505	6.58e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PNFEGDNE_00506	9.88e-244	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PNFEGDNE_00507	1.04e-79	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PNFEGDNE_00508	6.3e-104	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PNFEGDNE_00509	5.08e-241	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PNFEGDNE_00510	5.12e-78	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
PNFEGDNE_00511	1.22e-71	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	restriction endonuclease
PNFEGDNE_00512	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
PNFEGDNE_00513	1.71e-07	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
PNFEGDNE_00514	4.88e-146	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
PNFEGDNE_00515	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_00516	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_00519	3.45e-48	-	-	-	-	-	-	-	-
PNFEGDNE_00520	2.66e-86	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PNFEGDNE_00521	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PNFEGDNE_00522	2.45e-128	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PNFEGDNE_00523	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PNFEGDNE_00524	1.04e-131	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
PNFEGDNE_00525	2.21e-125	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PNFEGDNE_00526	3.34e-246	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PNFEGDNE_00527	3.85e-59	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PNFEGDNE_00528	4.61e-84	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PNFEGDNE_00529	2.06e-274	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PNFEGDNE_00530	3.3e-160	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PNFEGDNE_00531	9.99e-129	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
PNFEGDNE_00532	1.48e-139	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
PNFEGDNE_00533	3.66e-290	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PNFEGDNE_00534	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_00535	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_00537	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PNFEGDNE_00538	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PNFEGDNE_00539	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
PNFEGDNE_00540	3.09e-59	ykuL	-	-	S	-	-	-	CBS domain
PNFEGDNE_00541	3.44e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PNFEGDNE_00542	4.06e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PNFEGDNE_00543	9.23e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PNFEGDNE_00545	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PNFEGDNE_00546	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PNFEGDNE_00547	6.56e-163	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
PNFEGDNE_00548	1.22e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PNFEGDNE_00550	3.15e-69	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
PNFEGDNE_00551	1.76e-121	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_00552	8.93e-87	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PNFEGDNE_00553	3.93e-124	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
PNFEGDNE_00554	8.2e-131	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PNFEGDNE_00555	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
PNFEGDNE_00556	4.75e-95	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PNFEGDNE_00557	6.46e-296	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PNFEGDNE_00558	4.32e-283	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PNFEGDNE_00559	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
PNFEGDNE_00560	4.05e-88	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PNFEGDNE_00561	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PNFEGDNE_00562	8.5e-137	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PNFEGDNE_00563	3.51e-61	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PNFEGDNE_00564	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PNFEGDNE_00565	1.95e-94	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
PNFEGDNE_00566	4.01e-137	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PNFEGDNE_00567	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PNFEGDNE_00568	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PNFEGDNE_00569	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PNFEGDNE_00570	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PNFEGDNE_00571	3.33e-91	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PNFEGDNE_00572	2.94e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PNFEGDNE_00573	1.36e-40	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
PNFEGDNE_00574	4.98e-99	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PNFEGDNE_00575	2.96e-92	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PNFEGDNE_00576	4.81e-66	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PNFEGDNE_00577	1.86e-103	-	-	-	H	-	-	-	Nodulation protein S (NodS)
PNFEGDNE_00578	3.25e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PNFEGDNE_00579	3.18e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PNFEGDNE_00580	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PNFEGDNE_00581	3.48e-114	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PNFEGDNE_00582	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PNFEGDNE_00583	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
PNFEGDNE_00584	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PNFEGDNE_00585	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PNFEGDNE_00586	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_00587	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_00589	1.22e-93	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNFEGDNE_00590	1.14e-194	-	-	-	S	-	-	-	Protein of unknown function (DUF3644)
PNFEGDNE_00591	9.01e-18	-	-	-	-	-	-	-	-
PNFEGDNE_00592	8.01e-24	-	-	-	L	-	-	-	nuclease
PNFEGDNE_00593	4.78e-36	-	-	-	S	-	-	-	Short C-terminal domain
PNFEGDNE_00599	4.73e-23	-	-	-	K	-	-	-	transcriptional
PNFEGDNE_00600	1.29e-08	ansR	-	-	K	-	-	-	transcriptional
PNFEGDNE_00601	2.13e-149	-	-	-	K	-	-	-	Transcriptional regulator
PNFEGDNE_00608	6.03e-98	-	-	-	S	-	-	-	Siphovirus Gp157
PNFEGDNE_00609	1.01e-310	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PNFEGDNE_00610	1.79e-148	-	-	-	L	-	-	-	AAA domain
PNFEGDNE_00611	2.34e-108	-	-	-	-	-	-	-	-
PNFEGDNE_00612	2.58e-180	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
PNFEGDNE_00613	8.99e-293	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
PNFEGDNE_00614	1.27e-66	-	-	-	S	-	-	-	VRR_NUC
PNFEGDNE_00618	7.97e-37	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
PNFEGDNE_00621	3.31e-107	-	-	-	L	-	-	-	HNH nucleases
PNFEGDNE_00622	1.05e-107	-	-	-	L	-	-	-	Phage terminase, small subunit
PNFEGDNE_00623	0.0	-	-	-	S	-	-	-	Phage Terminase
PNFEGDNE_00625	3.31e-262	-	-	-	S	-	-	-	Phage portal protein
PNFEGDNE_00626	7.29e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
PNFEGDNE_00627	7.81e-282	-	-	-	S	-	-	-	Phage capsid family
PNFEGDNE_00628	3.09e-29	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PNFEGDNE_00629	1.56e-78	-	-	-	S	-	-	-	Phage head-tail joining protein
PNFEGDNE_00630	1.61e-84	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PNFEGDNE_00631	3.58e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
PNFEGDNE_00632	1.55e-158	-	-	-	S	-	-	-	Phage tail tube protein
PNFEGDNE_00633	7.85e-74	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
PNFEGDNE_00635	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PNFEGDNE_00636	4.38e-100	-	-	-	S	-	-	-	Phage tail protein
PNFEGDNE_00637	4.4e-153	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
PNFEGDNE_00643	7.49e-29	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
PNFEGDNE_00644	4.44e-146	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PNFEGDNE_00645	1.82e-49	-	-	-	-	-	-	-	-
PNFEGDNE_00646	4.68e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PNFEGDNE_00647	1.89e-75	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PNFEGDNE_00648	3.15e-200	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PNFEGDNE_00649	3.59e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PNFEGDNE_00650	9.42e-137	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PNFEGDNE_00652	1.46e-141	csrR	-	-	K	-	-	-	response regulator
PNFEGDNE_00653	1.09e-218	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PNFEGDNE_00654	4.16e-152	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PNFEGDNE_00655	1.6e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PNFEGDNE_00656	1.44e-171	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PNFEGDNE_00657	1.74e-142	-	-	-	-	-	-	-	-
PNFEGDNE_00658	1.14e-147	-	-	-	-	-	-	-	-
PNFEGDNE_00659	2.39e-47	-	-	-	S	-	-	-	Protein conserved in bacteria
PNFEGDNE_00660	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PNFEGDNE_00661	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PNFEGDNE_00662	7.18e-47	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PNFEGDNE_00663	3.85e-132	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PNFEGDNE_00664	9.95e-183	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PNFEGDNE_00665	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PNFEGDNE_00666	4.39e-104	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PNFEGDNE_00667	2.56e-153	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PNFEGDNE_00668	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PNFEGDNE_00669	5.81e-236	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PNFEGDNE_00670	1.29e-106	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PNFEGDNE_00671	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
PNFEGDNE_00672	3.28e-35	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
PNFEGDNE_00673	2.28e-118	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PNFEGDNE_00674	2.16e-58	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
PNFEGDNE_00675	9.32e-89	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
PNFEGDNE_00677	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PNFEGDNE_00678	1.8e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PNFEGDNE_00679	9.08e-90	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
PNFEGDNE_00680	2.47e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PNFEGDNE_00681	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PNFEGDNE_00682	2.92e-60	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PNFEGDNE_00683	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
PNFEGDNE_00684	1.42e-139	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PNFEGDNE_00685	1.28e-256	ynbB	-	-	P	-	-	-	aluminum resistance
PNFEGDNE_00686	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
PNFEGDNE_00687	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PNFEGDNE_00689	6.13e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PNFEGDNE_00690	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
PNFEGDNE_00691	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PNFEGDNE_00692	2.76e-103	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PNFEGDNE_00693	2.86e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PNFEGDNE_00694	4.52e-131	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PNFEGDNE_00695	2.52e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PNFEGDNE_00696	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PNFEGDNE_00697	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PNFEGDNE_00698	1.16e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PNFEGDNE_00699	1.25e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PNFEGDNE_00700	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PNFEGDNE_00701	4.38e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
PNFEGDNE_00702	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PNFEGDNE_00703	2.12e-72	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PNFEGDNE_00704	1.16e-151	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PNFEGDNE_00705	7.4e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PNFEGDNE_00706	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PNFEGDNE_00707	1.04e-74	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PNFEGDNE_00708	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PNFEGDNE_00709	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PNFEGDNE_00710	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PNFEGDNE_00712	1.74e-257	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNFEGDNE_00713	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_00714	1.83e-41	-	-	-	-	-	-	-	-
PNFEGDNE_00715	2.05e-138	ampC	-	-	V	-	-	-	Beta-lactamase
PNFEGDNE_00716	6.58e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
PNFEGDNE_00717	1.04e-277	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
PNFEGDNE_00718	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PNFEGDNE_00719	2.44e-229	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PNFEGDNE_00720	3.04e-113	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PNFEGDNE_00721	1.9e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PNFEGDNE_00722	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PNFEGDNE_00723	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PNFEGDNE_00724	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PNFEGDNE_00725	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PNFEGDNE_00726	1.99e-74	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PNFEGDNE_00727	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PNFEGDNE_00728	3.29e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PNFEGDNE_00729	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PNFEGDNE_00730	6.22e-70	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PNFEGDNE_00731	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PNFEGDNE_00732	1.21e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PNFEGDNE_00733	3.41e-114	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PNFEGDNE_00734	1.68e-17	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
PNFEGDNE_00737	2.39e-31	-	-	-	K	-	-	-	Helix-turn-helix domain
PNFEGDNE_00738	3.2e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNFEGDNE_00741	2.7e-60	-	-	-	S	-	-	-	DNA binding
PNFEGDNE_00746	6.29e-94	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
PNFEGDNE_00747	2.09e-109	-	-	-	S	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
PNFEGDNE_00750	6.73e-55	-	-	-	L	-	-	-	DnaD domain protein
PNFEGDNE_00753	4.42e-23	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
PNFEGDNE_00755	7.1e-38	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
PNFEGDNE_00756	8.05e-134	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
PNFEGDNE_00767	5.18e-42	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
PNFEGDNE_00768	2.37e-52	-	-	-	KL	-	-	-	DNA methylase
PNFEGDNE_00769	2.34e-90	-	-	-	S	-	-	-	ATPase activity
PNFEGDNE_00770	2.39e-53	-	-	-	L	-	-	-	transposase activity
PNFEGDNE_00771	5.04e-163	-	-	-	S	-	-	-	Terminase-like family
PNFEGDNE_00772	2.97e-201	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
PNFEGDNE_00775	1.3e-131	gpG	-	-	-	-	-	-	-
PNFEGDNE_00776	4.43e-46	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PNFEGDNE_00778	1.47e-43	-	-	-	-	-	-	-	-
PNFEGDNE_00779	9.1e-22	-	-	-	-	-	-	-	-
PNFEGDNE_00780	5.91e-57	-	-	-	-	-	-	-	-
PNFEGDNE_00783	7.41e-94	-	-	-	D	-	-	-	domain protein
PNFEGDNE_00784	7.29e-96	-	-	-	S	-	-	-	Phage tail protein
PNFEGDNE_00785	3.72e-95	-	-	-	M	-	-	-	Prophage endopeptidase tail
PNFEGDNE_00786	7.26e-120	-	-	-	M	-	-	-	Prophage endopeptidase tail
PNFEGDNE_00788	4.6e-32	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PNFEGDNE_00793	3.86e-14	-	-	-	S	-	-	-	Bacteriophage holin
PNFEGDNE_00794	1.05e-161	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PNFEGDNE_00796	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PNFEGDNE_00797	6.55e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PNFEGDNE_00798	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PNFEGDNE_00799	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PNFEGDNE_00800	8.06e-36	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
PNFEGDNE_00801	1.54e-119	-	-	-	M	-	-	-	Phosphotransferase enzyme family
PNFEGDNE_00802	4.13e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PNFEGDNE_00803	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PNFEGDNE_00804	3.76e-153	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PNFEGDNE_00805	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PNFEGDNE_00806	1.09e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PNFEGDNE_00807	1.02e-191	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PNFEGDNE_00808	1.11e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PNFEGDNE_00809	1.4e-238	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PNFEGDNE_00810	4.6e-144	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PNFEGDNE_00811	8e-76	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PNFEGDNE_00812	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PNFEGDNE_00813	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PNFEGDNE_00814	2.1e-303	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PNFEGDNE_00815	2.92e-306	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PNFEGDNE_00816	7.63e-181	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PNFEGDNE_00817	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PNFEGDNE_00818	4.17e-129	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PNFEGDNE_00819	2.33e-286	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PNFEGDNE_00820	5.26e-186	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PNFEGDNE_00821	6.15e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PNFEGDNE_00822	1.82e-262	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PNFEGDNE_00823	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PNFEGDNE_00824	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PNFEGDNE_00825	3.22e-74	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PNFEGDNE_00826	2.25e-144	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PNFEGDNE_00827	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PNFEGDNE_00828	2.91e-249	-	-	-	E	ko:K03294	-	ko00000	amino acid
PNFEGDNE_00829	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PNFEGDNE_00830	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PNFEGDNE_00831	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PNFEGDNE_00832	3.09e-146	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PNFEGDNE_00833	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PNFEGDNE_00834	0.000361	-	-	-	S	-	-	-	Tetratricopeptide repeat
PNFEGDNE_00835	9.71e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PNFEGDNE_00836	1.94e-245	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PNFEGDNE_00837	7.41e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PNFEGDNE_00838	3.87e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PNFEGDNE_00839	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PNFEGDNE_00840	1.72e-29	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PNFEGDNE_00841	3.51e-33	-	-	-	-	-	-	-	-
PNFEGDNE_00842	1.36e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PNFEGDNE_00843	4.73e-13	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
PNFEGDNE_00845	3.42e-31	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PNFEGDNE_00846	6.09e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
PNFEGDNE_00847	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PNFEGDNE_00848	1.09e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PNFEGDNE_00849	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PNFEGDNE_00850	2.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PNFEGDNE_00851	2.31e-125	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PNFEGDNE_00852	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PNFEGDNE_00853	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PNFEGDNE_00854	6.12e-95	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PNFEGDNE_00855	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PNFEGDNE_00856	1.48e-166	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PNFEGDNE_00857	6.07e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PNFEGDNE_00858	1.85e-40	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNFEGDNE_00859	4.77e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNFEGDNE_00860	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNFEGDNE_00861	3.04e-283	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PNFEGDNE_00862	1.99e-174	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PNFEGDNE_00863	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PNFEGDNE_00864	1.98e-291	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PNFEGDNE_00865	1.86e-200	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PNFEGDNE_00866	2.68e-135	-	-	-	S	-	-	-	Acyltransferase family
PNFEGDNE_00867	2.77e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PNFEGDNE_00868	2.58e-156	-	-	-	K	-	-	-	LysR substrate binding domain
PNFEGDNE_00870	6.94e-28	-	-	-	-	-	-	-	-
PNFEGDNE_00871	2.81e-74	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PNFEGDNE_00872	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PNFEGDNE_00873	5.91e-62	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PNFEGDNE_00874	2.43e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
PNFEGDNE_00875	1.24e-186	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PNFEGDNE_00876	2.07e-133	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PNFEGDNE_00877	2.02e-143	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PNFEGDNE_00878	2.67e-171	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PNFEGDNE_00879	3.59e-156	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PNFEGDNE_00880	1.48e-118	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
PNFEGDNE_00881	1.42e-273	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PNFEGDNE_00882	1.35e-46	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PNFEGDNE_00883	7.4e-180	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
PNFEGDNE_00884	3.45e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PNFEGDNE_00885	5.71e-72	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PNFEGDNE_00886	3.11e-108	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PNFEGDNE_00887	7.32e-101	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PNFEGDNE_00888	4.35e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PNFEGDNE_00889	8.36e-117	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PNFEGDNE_00890	4.25e-107	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PNFEGDNE_00891	3.08e-126	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PNFEGDNE_00894	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PNFEGDNE_00895	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PNFEGDNE_00896	5.36e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PNFEGDNE_00898	2.71e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PNFEGDNE_00899	3.12e-141	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PNFEGDNE_00900	1.85e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PNFEGDNE_00901	2.37e-166	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PNFEGDNE_00902	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_00903	1.36e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PNFEGDNE_00904	2.15e-73	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PNFEGDNE_00905	2.11e-93	-	-	-	C	-	-	-	Aldo keto reductase
PNFEGDNE_00906	9.22e-41	-	-	-	C	-	-	-	Aldo keto reductase
PNFEGDNE_00907	2.59e-31	-	-	-	K	-	-	-	regulatory protein
PNFEGDNE_00908	4.3e-141	ydhF	-	-	S	-	-	-	Aldo keto reductase
PNFEGDNE_00910	2.64e-100	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PNFEGDNE_00911	7.98e-69	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
PNFEGDNE_00912	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PNFEGDNE_00913	2.54e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PNFEGDNE_00914	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PNFEGDNE_00915	2.78e-106	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PNFEGDNE_00916	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PNFEGDNE_00917	3.72e-174	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PNFEGDNE_00918	7.35e-72	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PNFEGDNE_00919	1.34e-256	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
PNFEGDNE_00920	1.17e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNFEGDNE_00921	1.12e-165	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PNFEGDNE_00922	4.77e-254	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
PNFEGDNE_00924	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_00925	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_00926	5.49e-37	cas6	-	-	S	-	-	-	CRISPR-associated endoribonuclease Cas6
PNFEGDNE_00927	4.21e-255	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
PNFEGDNE_00928	6.4e-43	-	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
PNFEGDNE_00929	9.43e-89	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
PNFEGDNE_00930	2.97e-82	-	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
PNFEGDNE_00931	1.07e-86	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
PNFEGDNE_00932	1.35e-110	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PNFEGDNE_00933	2.56e-42	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PNFEGDNE_00934	1.38e-84	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PNFEGDNE_00935	1.45e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
PNFEGDNE_00936	1.69e-53	-	-	-	S	-	-	-	repeat protein
PNFEGDNE_00937	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PNFEGDNE_00939	8.63e-20	-	-	-	-	-	-	-	-
PNFEGDNE_00942	5.71e-110	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PNFEGDNE_00943	1.95e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PNFEGDNE_00944	3.97e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PNFEGDNE_00945	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PNFEGDNE_00946	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PNFEGDNE_00947	3.28e-163	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PNFEGDNE_00948	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PNFEGDNE_00949	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PNFEGDNE_00950	5.6e-17	-	-	-	-	-	-	-	-
PNFEGDNE_00951	1.76e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
PNFEGDNE_00952	5.19e-56	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
PNFEGDNE_00953	3.09e-149	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PNFEGDNE_00954	2.49e-96	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PNFEGDNE_00955	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PNFEGDNE_00956	3.59e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PNFEGDNE_00957	1.03e-71	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
PNFEGDNE_00958	3.83e-56	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PNFEGDNE_00959	1.19e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PNFEGDNE_00960	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PNFEGDNE_00961	7.51e-257	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PNFEGDNE_00962	1.29e-141	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PNFEGDNE_00963	3.66e-238	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PNFEGDNE_00964	6.09e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PNFEGDNE_00965	2.12e-114	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PNFEGDNE_00966	3.17e-173	-	-	-	K	-	-	-	Transcriptional regulator
PNFEGDNE_00967	1.09e-184	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PNFEGDNE_00968	4.04e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PNFEGDNE_00969	8.19e-218	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PNFEGDNE_00970	2.01e-110	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PNFEGDNE_00972	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PNFEGDNE_00973	6.61e-219	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PNFEGDNE_00974	3.11e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
PNFEGDNE_00975	4.15e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
PNFEGDNE_00976	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PNFEGDNE_00977	1.18e-15	-	-	-	-	-	-	-	-
PNFEGDNE_00982	2.24e-07	-	-	-	D	-	-	-	nuclear chromosome segregation
PNFEGDNE_00984	4.13e-185	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PNFEGDNE_00985	4.83e-98	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PNFEGDNE_00986	5.44e-130	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PNFEGDNE_00987	1.76e-232	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PNFEGDNE_00988	1.71e-90	-	-	-	L	-	-	-	DNA alkylation repair enzyme
PNFEGDNE_00989	9.93e-174	-	-	-	EG	-	-	-	EamA-like transporter family
PNFEGDNE_00990	2.24e-189	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PNFEGDNE_00991	3.65e-255	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PNFEGDNE_00992	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PNFEGDNE_00993	7.18e-173	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PNFEGDNE_00995	1.34e-220	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PNFEGDNE_00996	2e-164	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PNFEGDNE_00997	1.21e-104	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PNFEGDNE_00999	1.03e-118	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PNFEGDNE_01000	3.32e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PNFEGDNE_01001	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PNFEGDNE_01002	5.64e-256	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PNFEGDNE_01003	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PNFEGDNE_01004	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PNFEGDNE_01005	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PNFEGDNE_01006	1.7e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PNFEGDNE_01007	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PNFEGDNE_01009	6.49e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PNFEGDNE_01010	1.38e-106	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PNFEGDNE_01011	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PNFEGDNE_01012	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PNFEGDNE_01013	2.19e-252	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PNFEGDNE_01014	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
PNFEGDNE_01015	1.19e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
PNFEGDNE_01016	3.9e-91	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
PNFEGDNE_01017	3.72e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PNFEGDNE_01018	4.68e-97	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PNFEGDNE_01019	2.08e-121	-	-	-	EG	-	-	-	EamA-like transporter family
PNFEGDNE_01020	1.17e-105	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
PNFEGDNE_01021	2.3e-140	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
PNFEGDNE_01022	5.74e-26	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PNFEGDNE_01024	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PNFEGDNE_01025	1.17e-288	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PNFEGDNE_01026	3.19e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PNFEGDNE_01027	7.04e-78	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
PNFEGDNE_01028	3.32e-191	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PNFEGDNE_01029	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNFEGDNE_01030	1.84e-220	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PNFEGDNE_01031	3.08e-276	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNFEGDNE_01033	6.69e-115	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PNFEGDNE_01034	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PNFEGDNE_01035	4.18e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PNFEGDNE_01036	2.42e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PNFEGDNE_01037	5.08e-197	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PNFEGDNE_01038	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
PNFEGDNE_01039	1.02e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PNFEGDNE_01040	1.12e-15	-	-	-	M	-	-	-	Lysin motif
PNFEGDNE_01041	1.62e-156	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PNFEGDNE_01042	5.3e-80	-	-	-	S	-	-	-	Helix-turn-helix domain
PNFEGDNE_01043	6.24e-277	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PNFEGDNE_01044	3.42e-59	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
PNFEGDNE_01045	6.91e-153	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
PNFEGDNE_01046	9.4e-52	-	-	-	-	-	-	-	-
PNFEGDNE_01047	5.63e-110	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PNFEGDNE_01049	7.63e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PNFEGDNE_01050	1.46e-262	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PNFEGDNE_01051	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PNFEGDNE_01052	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PNFEGDNE_01053	3.77e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PNFEGDNE_01054	6.6e-86	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PNFEGDNE_01055	7.67e-118	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
PNFEGDNE_01056	2.96e-141	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNFEGDNE_01057	2.13e-14	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNFEGDNE_01058	1.65e-137	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PNFEGDNE_01059	5.57e-268	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PNFEGDNE_01060	1.42e-44	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PNFEGDNE_01061	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PNFEGDNE_01063	3.41e-103	-	-	-	F	-	-	-	Hydrolase, nudix family
PNFEGDNE_01064	1.34e-73	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PNFEGDNE_01065	1.64e-87	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PNFEGDNE_01066	4.54e-91	-	-	-	M	-	-	-	GNAT acetyltransferase
PNFEGDNE_01068	5.6e-244	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
PNFEGDNE_01069	3.75e-82	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PNFEGDNE_01070	1.31e-237	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PNFEGDNE_01071	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PNFEGDNE_01072	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PNFEGDNE_01073	1.29e-142	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PNFEGDNE_01074	8.77e-159	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PNFEGDNE_01075	6.67e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
PNFEGDNE_01076	8.84e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PNFEGDNE_01077	2.3e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PNFEGDNE_01078	3.83e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PNFEGDNE_01079	1.38e-75	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PNFEGDNE_01080	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNFEGDNE_01081	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PNFEGDNE_01082	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PNFEGDNE_01083	3.63e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
PNFEGDNE_01084	1.56e-225	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PNFEGDNE_01085	1.94e-124	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PNFEGDNE_01086	1.95e-89	-	-	-	-	-	-	-	-
PNFEGDNE_01088	1.21e-20	-	-	-	-	-	-	-	-
PNFEGDNE_01089	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PNFEGDNE_01090	7.69e-38	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
PNFEGDNE_01091	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PNFEGDNE_01099	5.42e-80	-	-	-	H	-	-	-	Methyltransferase domain
PNFEGDNE_01100	1.66e-90	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
PNFEGDNE_01101	9.68e-53	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
PNFEGDNE_01103	2.27e-29	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
PNFEGDNE_01104	3.99e-22	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PNFEGDNE_01105	1.01e-18	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PNFEGDNE_01107	3.76e-106	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
PNFEGDNE_01108	1.88e-42	-	-	-	S	-	-	-	CHY zinc finger
PNFEGDNE_01109	2.54e-53	ywnA	-	-	K	-	-	-	Transcriptional regulator
PNFEGDNE_01110	5.22e-71	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
PNFEGDNE_01113	3.23e-79	-	-	-	M	-	-	-	Glycosyl transferases group 1
PNFEGDNE_01114	3.03e-226	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PNFEGDNE_01115	8.82e-183	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	RmlD substrate binding domain
PNFEGDNE_01116	4.16e-128	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PNFEGDNE_01117	6.83e-75	-	-	-	M	-	-	-	Glycosyl transferases group 1
PNFEGDNE_01118	5.08e-142	-	-	-	S	-	-	-	Glycosyltransferase WbsX
PNFEGDNE_01120	1.24e-63	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PNFEGDNE_01121	2.04e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
PNFEGDNE_01122	3.11e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
PNFEGDNE_01123	7.67e-57	-	-	-	M	-	-	-	Glycosyltransferase Family 4
PNFEGDNE_01125	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01126	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01128	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01129	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01131	3.28e-94	-	-	-	M	-	-	-	glycosyl transferase group 1
PNFEGDNE_01132	1.81e-96	-	-	-	M	-	-	-	glycosyl transferase group 1
PNFEGDNE_01133	1.82e-156	-	-	-	M	-	-	-	Glycosyl transferases group 1
PNFEGDNE_01134	2.02e-52	-	-	-	S	ko:K13006,ko:K19429	-	ko00000,ko01000,ko01005	Bacterial transferase hexapeptide (six repeats)
PNFEGDNE_01135	3.59e-99	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
PNFEGDNE_01136	3.53e-209	epsN	-	-	M	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
PNFEGDNE_01137	2.58e-87	capD	-	-	M	-	-	-	CoA-binding domain
PNFEGDNE_01138	6.93e-166	capD	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
PNFEGDNE_01139	6.61e-83	-	-	-	D	-	-	-	AAA domain
PNFEGDNE_01140	1.57e-59	-	-	-	M	-	-	-	Chain length determinant protein
PNFEGDNE_01141	3.33e-52	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PNFEGDNE_01142	1.13e-223	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PNFEGDNE_01143	3.87e-82	-	-	-	-	-	-	-	-
PNFEGDNE_01144	2.26e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
PNFEGDNE_01145	5.02e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PNFEGDNE_01146	5.26e-76	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PNFEGDNE_01147	2.82e-240	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PNFEGDNE_01148	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PNFEGDNE_01149	1.85e-265	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PNFEGDNE_01151	8.38e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PNFEGDNE_01152	5.51e-69	-	-	-	S	-	-	-	Membrane
PNFEGDNE_01153	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PNFEGDNE_01155	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01156	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01157	1.1e-78	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PNFEGDNE_01158	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PNFEGDNE_01159	8.4e-66	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PNFEGDNE_01160	6.72e-117	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
PNFEGDNE_01161	6.61e-36	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PNFEGDNE_01162	4.61e-153	-	-	-	T	-	-	-	diguanylate cyclase activity
PNFEGDNE_01163	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
PNFEGDNE_01164	8.55e-256	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
PNFEGDNE_01165	2.39e-193	-	-	-	S	-	-	-	Protein conserved in bacteria
PNFEGDNE_01166	9.67e-44	-	-	-	S	-	-	-	Protein conserved in bacteria
PNFEGDNE_01167	4.41e-236	-	-	-	-	-	-	-	-
PNFEGDNE_01168	7.49e-161	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PNFEGDNE_01169	4.34e-18	-	-	-	T	-	-	-	diguanylate cyclase
PNFEGDNE_01170	1.02e-182	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
PNFEGDNE_01171	6.22e-197	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PNFEGDNE_01172	1.73e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PNFEGDNE_01173	4.59e-121	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PNFEGDNE_01174	9.93e-276	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
PNFEGDNE_01175	1.34e-254	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PNFEGDNE_01176	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PNFEGDNE_01177	1.84e-244	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PNFEGDNE_01178	2.32e-203	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PNFEGDNE_01179	3.05e-48	-	-	-	M	-	-	-	LysM domain
PNFEGDNE_01180	1.38e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
PNFEGDNE_01181	1.8e-67	-	-	-	M	-	-	-	LysM domain protein
PNFEGDNE_01182	7.86e-116	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PNFEGDNE_01183	4.26e-108	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PNFEGDNE_01185	8.05e-91	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
PNFEGDNE_01186	1.15e-118	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PNFEGDNE_01188	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01189	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01190	3.43e-06	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PNFEGDNE_01191	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PNFEGDNE_01192	1.61e-91	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PNFEGDNE_01193	5.69e-104	ylmH	-	-	S	-	-	-	S4 domain protein
PNFEGDNE_01194	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PNFEGDNE_01195	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PNFEGDNE_01196	4.52e-229	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PNFEGDNE_01197	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PNFEGDNE_01198	9.12e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PNFEGDNE_01199	8.63e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PNFEGDNE_01200	2.97e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PNFEGDNE_01201	3.64e-172	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PNFEGDNE_01202	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PNFEGDNE_01203	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
PNFEGDNE_01204	4.28e-179	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PNFEGDNE_01205	2.65e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PNFEGDNE_01207	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
PNFEGDNE_01208	4.54e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PNFEGDNE_01209	3.24e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PNFEGDNE_01210	2.01e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_01211	4.29e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PNFEGDNE_01212	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
PNFEGDNE_01213	3.56e-98	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PNFEGDNE_01214	9.34e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
PNFEGDNE_01215	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PNFEGDNE_01216	2.35e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PNFEGDNE_01217	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
PNFEGDNE_01218	2.27e-102	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PNFEGDNE_01219	8.51e-170	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PNFEGDNE_01220	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PNFEGDNE_01221	5.85e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PNFEGDNE_01222	1.45e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PNFEGDNE_01223	2.45e-225	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PNFEGDNE_01224	1.49e-71	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PNFEGDNE_01225	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PNFEGDNE_01226	6.66e-30	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PNFEGDNE_01227	3.85e-246	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PNFEGDNE_01229	3.67e-96	uspA	-	-	T	-	-	-	universal stress protein
PNFEGDNE_01230	2.15e-69	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PNFEGDNE_01231	2.99e-252	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PNFEGDNE_01232	2.95e-158	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PNFEGDNE_01234	5.2e-09	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PNFEGDNE_01235	7.25e-80	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PNFEGDNE_01236	3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PNFEGDNE_01237	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PNFEGDNE_01238	0.0	-	-	-	S	-	-	-	membrane
PNFEGDNE_01239	4.3e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PNFEGDNE_01240	1.89e-265	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PNFEGDNE_01241	1.68e-128	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
PNFEGDNE_01242	3.04e-179	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PNFEGDNE_01244	4.8e-22	-	-	-	-	-	-	-	-
PNFEGDNE_01245	1.03e-254	oatA	-	-	I	-	-	-	Acyltransferase
PNFEGDNE_01246	3.33e-272	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PNFEGDNE_01247	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PNFEGDNE_01248	8.53e-179	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNFEGDNE_01251	1.47e-52	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PNFEGDNE_01252	1.79e-93	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PNFEGDNE_01253	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PNFEGDNE_01254	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PNFEGDNE_01255	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PNFEGDNE_01256	4.27e-19	cvpA	-	-	S	-	-	-	Colicin V production protein
PNFEGDNE_01257	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PNFEGDNE_01258	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PNFEGDNE_01259	1.57e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PNFEGDNE_01260	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PNFEGDNE_01261	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PNFEGDNE_01262	8.64e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PNFEGDNE_01263	1.25e-153	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PNFEGDNE_01264	3.5e-18	-	-	-	-	-	-	-	-
PNFEGDNE_01265	5.55e-184	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PNFEGDNE_01266	1.35e-86	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
PNFEGDNE_01267	7.03e-311	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
PNFEGDNE_01268	2.9e-149	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
PNFEGDNE_01269	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
PNFEGDNE_01271	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
PNFEGDNE_01273	3.02e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
PNFEGDNE_01274	5.96e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PNFEGDNE_01275	4.77e-230	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PNFEGDNE_01276	7.18e-194	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PNFEGDNE_01277	1.54e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PNFEGDNE_01278	6.99e-288	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PNFEGDNE_01279	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PNFEGDNE_01280	4.38e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PNFEGDNE_01281	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PNFEGDNE_01282	4.22e-111	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PNFEGDNE_01283	1.06e-84	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PNFEGDNE_01284	5.2e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PNFEGDNE_01285	2.24e-187	ymfH	-	-	S	-	-	-	Peptidase M16
PNFEGDNE_01286	4.21e-136	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PNFEGDNE_01287	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PNFEGDNE_01288	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PNFEGDNE_01289	3.33e-123	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
PNFEGDNE_01290	1.44e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
PNFEGDNE_01291	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PNFEGDNE_01292	2.44e-250	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PNFEGDNE_01293	8.5e-24	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
PNFEGDNE_01294	1.87e-164	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PNFEGDNE_01295	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PNFEGDNE_01296	1.1e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PNFEGDNE_01297	5.14e-86	ybbR	-	-	S	-	-	-	YbbR-like protein
PNFEGDNE_01298	1.95e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PNFEGDNE_01299	3.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
PNFEGDNE_01300	3.49e-145	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PNFEGDNE_01301	3.34e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PNFEGDNE_01302	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PNFEGDNE_01303	7.01e-181	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PNFEGDNE_01304	1.52e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PNFEGDNE_01305	1.68e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PNFEGDNE_01306	1.94e-53	-	-	-	-	-	-	-	-
PNFEGDNE_01307	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PNFEGDNE_01308	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PNFEGDNE_01309	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PNFEGDNE_01310	2.34e-210	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PNFEGDNE_01312	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01313	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01314	5.39e-189	-	-	-	E	-	-	-	Major Facilitator Superfamily
PNFEGDNE_01315	8.04e-212	yclK	-	-	T	-	-	-	Histidine kinase
PNFEGDNE_01316	3.94e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PNFEGDNE_01317	1.29e-164	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PNFEGDNE_01318	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PNFEGDNE_01319	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PNFEGDNE_01320	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PNFEGDNE_01321	2.39e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PNFEGDNE_01322	3.92e-175	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
PNFEGDNE_01324	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PNFEGDNE_01325	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PNFEGDNE_01326	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PNFEGDNE_01327	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PNFEGDNE_01328	4.6e-101	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
PNFEGDNE_01329	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PNFEGDNE_01330	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PNFEGDNE_01331	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PNFEGDNE_01332	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PNFEGDNE_01333	8.29e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PNFEGDNE_01334	5.85e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PNFEGDNE_01335	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
PNFEGDNE_01336	1.44e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
PNFEGDNE_01337	7.39e-104	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PNFEGDNE_01338	4.19e-110	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PNFEGDNE_01339	4.95e-81	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
PNFEGDNE_01340	1.85e-206	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PNFEGDNE_01341	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PNFEGDNE_01342	1.49e-121	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
PNFEGDNE_01343	2.03e-104	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PNFEGDNE_01344	1.13e-68	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PNFEGDNE_01345	1.51e-159	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PNFEGDNE_01346	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
PNFEGDNE_01347	0.0	ydaO	-	-	E	-	-	-	amino acid
PNFEGDNE_01348	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
PNFEGDNE_01349	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PNFEGDNE_01350	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PNFEGDNE_01351	4.03e-41	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PNFEGDNE_01352	5.32e-127	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PNFEGDNE_01353	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PNFEGDNE_01354	2.51e-206	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PNFEGDNE_01355	1.9e-19	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PNFEGDNE_01356	3.7e-88	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PNFEGDNE_01357	2.82e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
PNFEGDNE_01358	8.56e-105	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PNFEGDNE_01359	1.15e-119	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PNFEGDNE_01360	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PNFEGDNE_01361	2.31e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PNFEGDNE_01362	2.18e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PNFEGDNE_01363	4.16e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PNFEGDNE_01364	3.83e-125	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PNFEGDNE_01365	3.64e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PNFEGDNE_01366	7.73e-268	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PNFEGDNE_01367	2.23e-80	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PNFEGDNE_01368	1.11e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PNFEGDNE_01369	3.91e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
PNFEGDNE_01370	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
PNFEGDNE_01371	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNFEGDNE_01372	1.28e-202	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNFEGDNE_01373	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PNFEGDNE_01374	1.8e-71	-	-	-	-	-	-	-	-
PNFEGDNE_01375	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PNFEGDNE_01376	2.21e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PNFEGDNE_01377	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PNFEGDNE_01378	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PNFEGDNE_01379	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PNFEGDNE_01380	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PNFEGDNE_01381	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PNFEGDNE_01382	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
PNFEGDNE_01383	1.88e-138	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PNFEGDNE_01384	3.45e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PNFEGDNE_01385	2.26e-263	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PNFEGDNE_01386	7.38e-313	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PNFEGDNE_01387	1.38e-195	yacL	-	-	S	-	-	-	domain protein
PNFEGDNE_01388	2.79e-284	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PNFEGDNE_01389	8.32e-96	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PNFEGDNE_01390	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
PNFEGDNE_01391	5.18e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PNFEGDNE_01392	3.93e-45	-	-	-	S	-	-	-	Enterocin A Immunity
PNFEGDNE_01393	4.1e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PNFEGDNE_01394	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
PNFEGDNE_01395	7.6e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PNFEGDNE_01397	9.77e-56	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PNFEGDNE_01398	2.72e-314	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
PNFEGDNE_01399	3.76e-165	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PNFEGDNE_01400	3.1e-307	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PNFEGDNE_01401	2.34e-113	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PNFEGDNE_01402	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PNFEGDNE_01403	7.04e-114	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PNFEGDNE_01406	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PNFEGDNE_01410	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PNFEGDNE_01411	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
PNFEGDNE_01412	1.02e-164	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PNFEGDNE_01413	3.03e-162	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PNFEGDNE_01414	1.9e-205	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PNFEGDNE_01415	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PNFEGDNE_01416	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PNFEGDNE_01417	1.5e-22	-	-	-	-	-	-	-	-
PNFEGDNE_01418	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PNFEGDNE_01419	7.16e-31	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PNFEGDNE_01420	6.64e-131	-	-	-	G	-	-	-	MucBP domain
PNFEGDNE_01421	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PNFEGDNE_01422	2.98e-253	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PNFEGDNE_01423	1.04e-206	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PNFEGDNE_01424	1.07e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PNFEGDNE_01425	4.55e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PNFEGDNE_01426	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PNFEGDNE_01427	1.25e-213	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
PNFEGDNE_01428	3.35e-228	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
PNFEGDNE_01429	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PNFEGDNE_01430	1.97e-146	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PNFEGDNE_01431	2.2e-200	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PNFEGDNE_01432	2.02e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
PNFEGDNE_01433	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
PNFEGDNE_01434	3.65e-241	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PNFEGDNE_01435	3.85e-80	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PNFEGDNE_01437	3.16e-30	-	-	-	S	-	-	-	Cytochrome B5
PNFEGDNE_01438	7.55e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PNFEGDNE_01439	1.66e-74	-	-	-	-	-	-	-	-
PNFEGDNE_01440	1.8e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PNFEGDNE_01441	6.62e-196	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
PNFEGDNE_01442	2.13e-115	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
PNFEGDNE_01443	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PNFEGDNE_01445	2.17e-181	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PNFEGDNE_01446	1.5e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PNFEGDNE_01447	1.32e-282	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PNFEGDNE_01448	2.32e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PNFEGDNE_01449	7.68e-82	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
PNFEGDNE_01450	4.35e-77	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PNFEGDNE_01452	3.54e-103	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PNFEGDNE_01453	1.01e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PNFEGDNE_01456	1.02e-97	-	-	-	S	-	-	-	Cell surface protein
PNFEGDNE_01458	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
PNFEGDNE_01459	1.59e-79	-	-	-	-	-	-	-	-
PNFEGDNE_01460	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PNFEGDNE_01461	1.3e-238	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PNFEGDNE_01462	4.42e-253	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PNFEGDNE_01465	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PNFEGDNE_01466	1.75e-57	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PNFEGDNE_01467	1.8e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PNFEGDNE_01468	4.07e-109	-	-	-	F	-	-	-	glutamine amidotransferase
PNFEGDNE_01469	3.45e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
PNFEGDNE_01470	1.24e-111	-	-	-	S	-	-	-	hydrolase
PNFEGDNE_01471	8.81e-123	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
PNFEGDNE_01473	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01474	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01475	5.1e-10	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
PNFEGDNE_01477	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
PNFEGDNE_01478	1.16e-89	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	COG0732 Restriction endonuclease S subunits
PNFEGDNE_01479	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PNFEGDNE_01481	7.74e-155	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
PNFEGDNE_01482	9.55e-99	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
PNFEGDNE_01483	4.12e-67	-	-	-	L	-	-	-	Type II restriction endonuclease, Alw26I Eco31I Esp3I family
PNFEGDNE_01485	1.48e-29	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PNFEGDNE_01486	9.5e-158	-	-	-	F	-	-	-	helicase superfamily c-terminal domain
PNFEGDNE_01488	1.83e-91	-	-	-	K	-	-	-	DNA-templated transcription, initiation
PNFEGDNE_01489	5.3e-40	-	-	-	-	-	-	-	-
PNFEGDNE_01490	9.8e-55	-	-	-	-	-	-	-	-
PNFEGDNE_01491	4.54e-264	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
PNFEGDNE_01492	1.24e-124	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
PNFEGDNE_01493	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
PNFEGDNE_01494	6.16e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PNFEGDNE_01495	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
PNFEGDNE_01496	7.2e-61	-	-	-	S	-	-	-	VRR_NUC
PNFEGDNE_01497	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
PNFEGDNE_01498	1.45e-112	-	-	-	-	-	-	-	-
PNFEGDNE_01499	3.28e-128	-	-	-	-	-	-	-	-
PNFEGDNE_01500	2.23e-297	-	-	-	KL	-	-	-	DNA methylase
PNFEGDNE_01501	5.06e-59	-	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase family 21
PNFEGDNE_01503	1.56e-132	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PNFEGDNE_01504	1.19e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
PNFEGDNE_01505	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
PNFEGDNE_01506	5.35e-307	-	-	-	S	-	-	-	Phage portal protein
PNFEGDNE_01507	4.66e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
PNFEGDNE_01508	1.29e-281	-	-	-	S	-	-	-	Phage capsid family
PNFEGDNE_01509	3.08e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PNFEGDNE_01510	1.29e-88	-	-	-	S	-	-	-	Phage head-tail joining protein
PNFEGDNE_01511	5.95e-92	-	-	-	S	-	-	-	Bacteriophage holin family
PNFEGDNE_01512	7.5e-185	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PNFEGDNE_01513	1.03e-37	-	-	-	-	-	-	-	-
PNFEGDNE_01514	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
PNFEGDNE_01515	0.0	-	-	-	L	-	-	-	Recombinase
PNFEGDNE_01516	0.0	-	-	-	M	-	-	-	domain protein
PNFEGDNE_01517	7.25e-269	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PNFEGDNE_01518	8.82e-184	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PNFEGDNE_01519	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PNFEGDNE_01520	7.24e-295	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PNFEGDNE_01521	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PNFEGDNE_01522	6.9e-205	camS	-	-	S	-	-	-	sex pheromone
PNFEGDNE_01523	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PNFEGDNE_01524	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PNFEGDNE_01526	5.26e-183	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PNFEGDNE_01530	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PNFEGDNE_01531	1.39e-213	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PNFEGDNE_01532	6.53e-167	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PNFEGDNE_01533	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PNFEGDNE_01534	2.49e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PNFEGDNE_01535	1.14e-118	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PNFEGDNE_01536	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
PNFEGDNE_01537	1.49e-28	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PNFEGDNE_01538	1.1e-42	yabO	-	-	J	-	-	-	S4 domain protein
PNFEGDNE_01539	4.66e-173	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PNFEGDNE_01540	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PNFEGDNE_01541	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PNFEGDNE_01542	4.55e-201	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PNFEGDNE_01543	3.64e-109	-	-	-	S	-	-	-	(CBS) domain
PNFEGDNE_01544	4.44e-180	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PNFEGDNE_01545	4.76e-260	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PNFEGDNE_01546	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PNFEGDNE_01547	1.42e-73	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
PNFEGDNE_01548	1.03e-125	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
PNFEGDNE_01549	1.77e-143	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PNFEGDNE_01550	1.18e-61	-	-	-	M	-	-	-	LysM domain protein
PNFEGDNE_01551	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PNFEGDNE_01552	7.29e-111	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PNFEGDNE_01553	2.6e-42	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
PNFEGDNE_01554	9.3e-139	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PNFEGDNE_01555	1.28e-110	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_01556	1.09e-87	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PNFEGDNE_01557	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PNFEGDNE_01558	4.89e-308	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PNFEGDNE_01560	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PNFEGDNE_01561	6.01e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PNFEGDNE_01562	6.22e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PNFEGDNE_01563	3.1e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNFEGDNE_01564	6.64e-139	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNFEGDNE_01565	5.59e-128	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNFEGDNE_01566	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PNFEGDNE_01567	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNFEGDNE_01568	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PNFEGDNE_01569	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PNFEGDNE_01570	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PNFEGDNE_01571	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PNFEGDNE_01572	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PNFEGDNE_01573	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PNFEGDNE_01574	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PNFEGDNE_01575	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PNFEGDNE_01576	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PNFEGDNE_01577	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PNFEGDNE_01578	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PNFEGDNE_01579	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PNFEGDNE_01580	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PNFEGDNE_01581	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PNFEGDNE_01582	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PNFEGDNE_01583	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PNFEGDNE_01584	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PNFEGDNE_01585	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PNFEGDNE_01586	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PNFEGDNE_01587	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PNFEGDNE_01588	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PNFEGDNE_01589	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PNFEGDNE_01590	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PNFEGDNE_01591	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PNFEGDNE_01592	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PNFEGDNE_01593	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PNFEGDNE_01594	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PNFEGDNE_01595	2.1e-218	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PNFEGDNE_01596	2.64e-101	-	-	-	K	-	-	-	rpiR family
PNFEGDNE_01597	4.04e-69	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PNFEGDNE_01598	1.68e-187	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PNFEGDNE_01599	1.1e-13	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PNFEGDNE_01600	5.79e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PNFEGDNE_01601	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNFEGDNE_01602	6.94e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNFEGDNE_01603	3.96e-125	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNFEGDNE_01604	1.72e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_01605	3.89e-17	-	-	-	-	-	-	-	-
PNFEGDNE_01606	3.17e-123	-	-	-	-	-	-	-	-
PNFEGDNE_01607	5.33e-17	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
PNFEGDNE_01608	1e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PNFEGDNE_01609	6.14e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PNFEGDNE_01610	5.89e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PNFEGDNE_01611	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PNFEGDNE_01612	8.78e-102	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PNFEGDNE_01613	3.94e-231	yhdP	-	-	S	-	-	-	Transporter associated domain
PNFEGDNE_01614	2.08e-22	-	-	-	-	-	-	-	-
PNFEGDNE_01615	3.19e-97	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PNFEGDNE_01616	1.13e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PNFEGDNE_01617	1.13e-125	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PNFEGDNE_01618	1.99e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PNFEGDNE_01619	1.97e-199	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PNFEGDNE_01620	1.6e-173	-	-	-	V	-	-	-	MatE
PNFEGDNE_01621	1.32e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNFEGDNE_01622	3.17e-110	-	-	-	S	-	-	-	Alpha beta hydrolase
PNFEGDNE_01623	3.54e-120	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PNFEGDNE_01624	3.68e-219	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PNFEGDNE_01625	1.24e-137	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
PNFEGDNE_01626	1.49e-129	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PNFEGDNE_01627	8.54e-45	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
PNFEGDNE_01628	1.09e-68	ccl	-	-	S	-	-	-	QueT transporter
PNFEGDNE_01630	1.07e-82	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PNFEGDNE_01631	3.37e-28	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PNFEGDNE_01632	3.11e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PNFEGDNE_01633	7.86e-46	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PNFEGDNE_01634	1.48e-110	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PNFEGDNE_01635	1.52e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PNFEGDNE_01636	1.19e-65	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PNFEGDNE_01637	3.89e-103	-	-	-	S	-	-	-	Putative threonine/serine exporter
PNFEGDNE_01638	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PNFEGDNE_01639	1.77e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
PNFEGDNE_01640	5.04e-118	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PNFEGDNE_01641	1.71e-27	-	-	-	-	-	-	-	-
PNFEGDNE_01642	1.5e-73	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
PNFEGDNE_01643	4.48e-24	-	-	-	-	-	-	-	-
PNFEGDNE_01644	3.45e-81	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PNFEGDNE_01645	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
PNFEGDNE_01646	3.58e-132	-	-	-	E	-	-	-	AzlC protein
PNFEGDNE_01647	2.11e-23	-	-	-	-	-	-	-	-
PNFEGDNE_01648	5.1e-163	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PNFEGDNE_01649	1.25e-156	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
PNFEGDNE_01656	2.43e-09	-	-	-	S	-	-	-	Mor transcription activator family
PNFEGDNE_01657	3.27e-73	-	-	-	K	-	-	-	WYL domain
PNFEGDNE_01658	3.53e-158	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PNFEGDNE_01659	4.47e-217	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PNFEGDNE_01660	7.91e-149	ydbI	-	-	K	-	-	-	AI-2E family transporter
PNFEGDNE_01661	2.37e-75	-	-	-	EG	-	-	-	EamA-like transporter family
PNFEGDNE_01662	1.06e-96	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
PNFEGDNE_01663	4.86e-148	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PNFEGDNE_01664	2.21e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PNFEGDNE_01665	5.43e-209	-	-	-	C	-	-	-	Luciferase-like monooxygenase
PNFEGDNE_01666	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PNFEGDNE_01667	6.68e-219	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PNFEGDNE_01668	2.09e-132	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PNFEGDNE_01669	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PNFEGDNE_01670	3.43e-106	pncA	-	-	Q	-	-	-	isochorismatase
PNFEGDNE_01671	1.14e-81	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
PNFEGDNE_01672	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PNFEGDNE_01673	1.68e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PNFEGDNE_01674	5.26e-316	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PNFEGDNE_01675	2.77e-211	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PNFEGDNE_01677	4.04e-230	XK27_08315	-	-	M	-	-	-	Sulfatase
PNFEGDNE_01678	4.61e-67	-	-	-	S	-	-	-	peptidoglycan catabolic process
PNFEGDNE_01679	4.51e-198	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
PNFEGDNE_01680	8.79e-109	-	-	-	M	-	-	-	Nucleotidyl transferase
PNFEGDNE_01681	8.04e-220	-	-	-	M	-	-	-	Choline/ethanolamine kinase
PNFEGDNE_01682	3.78e-112	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PNFEGDNE_01683	5.93e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PNFEGDNE_01684	8.54e-161	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PNFEGDNE_01685	9.8e-222	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
PNFEGDNE_01686	1.52e-153	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
PNFEGDNE_01687	4.55e-20	-	-	-	-	-	-	-	-
PNFEGDNE_01688	4.15e-91	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PNFEGDNE_01689	2.13e-185	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
PNFEGDNE_01690	6.99e-66	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
PNFEGDNE_01691	8.36e-196	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PNFEGDNE_01692	4.32e-86	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PNFEGDNE_01693	3.27e-120	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PNFEGDNE_01694	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PNFEGDNE_01695	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PNFEGDNE_01697	2.97e-193	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PNFEGDNE_01698	5.53e-247	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PNFEGDNE_01699	3.1e-43	-	-	-	S	-	-	-	Acyltransferase family
PNFEGDNE_01701	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01702	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01707	1.02e-79	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PNFEGDNE_01708	2.14e-92	licD1	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
PNFEGDNE_01709	1.23e-67	-	-	-	-	-	-	-	-
PNFEGDNE_01710	9.51e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PNFEGDNE_01711	1.21e-83	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
PNFEGDNE_01712	4.86e-115	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
PNFEGDNE_01713	9.91e-47	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PNFEGDNE_01714	5.87e-80	-	-	-	D	-	-	-	Peptidase family M23
PNFEGDNE_01716	2.41e-163	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PNFEGDNE_01717	3.12e-214	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PNFEGDNE_01718	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PNFEGDNE_01719	9.87e-184	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PNFEGDNE_01720	1.19e-115	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
PNFEGDNE_01721	7.11e-75	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
PNFEGDNE_01722	2.34e-47	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PNFEGDNE_01723	3.44e-26	-	-	-	L	ko:K07482	-	ko00000	Integrase
PNFEGDNE_01724	4.8e-95	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PNFEGDNE_01725	7.64e-27	-	-	-	-	-	-	-	-
PNFEGDNE_01726	5.17e-12	-	-	-	K	-	-	-	SIR2-like domain
PNFEGDNE_01727	8.18e-87	-	-	-	K	-	-	-	SIR2-like domain
PNFEGDNE_01728	6.37e-141	-	-	-	K	-	-	-	IrrE N-terminal-like domain
PNFEGDNE_01730	4.35e-48	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PNFEGDNE_01731	5.89e-60	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
PNFEGDNE_01732	7.73e-62	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
PNFEGDNE_01733	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PNFEGDNE_01734	9.14e-170	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PNFEGDNE_01735	3.94e-56	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PNFEGDNE_01736	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_01737	2e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PNFEGDNE_01738	6.18e-267	potE	-	-	E	-	-	-	Amino Acid
PNFEGDNE_01739	2.51e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
PNFEGDNE_01740	1.78e-171	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
PNFEGDNE_01741	6.25e-77	-	-	-	S	-	-	-	Glycosyltransferase like family 2
PNFEGDNE_01742	2.44e-149	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PNFEGDNE_01743	2.09e-46	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PNFEGDNE_01744	1.3e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PNFEGDNE_01745	1.03e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PNFEGDNE_01746	3.16e-192	-	-	-	EGP	-	-	-	Major Facilitator
PNFEGDNE_01748	8.92e-87	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PNFEGDNE_01749	1.17e-35	adhR	-	-	K	-	-	-	transcriptional regulator
PNFEGDNE_01750	7.64e-114	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PNFEGDNE_01751	3.49e-130	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PNFEGDNE_01752	1.98e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PNFEGDNE_01753	2.44e-138	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PNFEGDNE_01754	6.5e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PNFEGDNE_01755	5.14e-132	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PNFEGDNE_01756	9.82e-47	-	-	-	-	-	-	-	-
PNFEGDNE_01757	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01758	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01760	3.04e-20	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PNFEGDNE_01761	2.21e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PNFEGDNE_01762	1.7e-241	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PNFEGDNE_01763	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PNFEGDNE_01764	2.39e-137	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PNFEGDNE_01765	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PNFEGDNE_01766	6.46e-85	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PNFEGDNE_01767	2.97e-129	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PNFEGDNE_01768	4.74e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PNFEGDNE_01769	2.48e-89	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
PNFEGDNE_01770	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PNFEGDNE_01771	1.36e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
PNFEGDNE_01772	6.05e-94	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PNFEGDNE_01774	2.06e-82	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PNFEGDNE_01775	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PNFEGDNE_01776	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PNFEGDNE_01777	1.75e-45	-	-	-	-	-	-	-	-
PNFEGDNE_01778	1.52e-177	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PNFEGDNE_01779	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PNFEGDNE_01780	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PNFEGDNE_01781	6.66e-198	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PNFEGDNE_01782	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
PNFEGDNE_01784	3.12e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_01785	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
PNFEGDNE_01786	2.33e-233	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
PNFEGDNE_01787	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PNFEGDNE_01788	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PNFEGDNE_01789	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
PNFEGDNE_01790	1.86e-49	-	-	-	K	-	-	-	Transcriptional regulator
PNFEGDNE_01791	3.36e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PNFEGDNE_01792	1.17e-127	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_01793	4.55e-133	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNFEGDNE_01795	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PNFEGDNE_01796	9.47e-259	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
PNFEGDNE_01797	3.71e-71	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PNFEGDNE_01798	1.18e-129	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PNFEGDNE_01799	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PNFEGDNE_01800	1.7e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
PNFEGDNE_01801	3.28e-87	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
PNFEGDNE_01802	8.78e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
PNFEGDNE_01803	3.63e-145	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
PNFEGDNE_01804	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNFEGDNE_01805	6.79e-263	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PNFEGDNE_01807	1.68e-140	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
PNFEGDNE_01808	4.35e-240	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
PNFEGDNE_01809	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PNFEGDNE_01810	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PNFEGDNE_01811	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PNFEGDNE_01812	1.32e-74	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
PNFEGDNE_01813	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
PNFEGDNE_01814	1.46e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
PNFEGDNE_01815	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PNFEGDNE_01816	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
PNFEGDNE_01817	1.3e-67	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PNFEGDNE_01818	8.75e-60	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
PNFEGDNE_01819	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PNFEGDNE_01820	3.19e-139	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
PNFEGDNE_01822	2.05e-86	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PNFEGDNE_01823	5.56e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PNFEGDNE_01824	1.3e-52	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
PNFEGDNE_01826	4.2e-45	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
PNFEGDNE_01827	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PNFEGDNE_01828	2.34e-122	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_01829	4.5e-25	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNFEGDNE_01832	1.16e-93	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNFEGDNE_01833	9.06e-152	ytbE	-	-	S	-	-	-	reductase
PNFEGDNE_01834	1.22e-57	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
PNFEGDNE_01835	2.53e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PNFEGDNE_01836	1.39e-52	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
PNFEGDNE_01837	7.94e-17	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNFEGDNE_01838	1.22e-207	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
PNFEGDNE_01839	5.58e-69	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PNFEGDNE_01840	1.03e-59	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PNFEGDNE_01841	1.17e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PNFEGDNE_01842	2.6e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
PNFEGDNE_01844	2.35e-51	-	-	-	K	-	-	-	LytTr DNA-binding domain
PNFEGDNE_01845	9.27e-145	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PNFEGDNE_01846	5.54e-264	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PNFEGDNE_01847	1.85e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
PNFEGDNE_01848	9.89e-197	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PNFEGDNE_01849	3.5e-229	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PNFEGDNE_01850	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNFEGDNE_01851	1.97e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNFEGDNE_01852	2.65e-255	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PNFEGDNE_01853	5.46e-276	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PNFEGDNE_01854	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PNFEGDNE_01855	4.38e-72	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PNFEGDNE_01856	1.28e-77	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
PNFEGDNE_01857	1.33e-313	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PNFEGDNE_01858	4.15e-26	-	-	-	S	-	-	-	Cupredoxin-like domain
PNFEGDNE_01859	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
PNFEGDNE_01860	2.04e-189	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PNFEGDNE_01861	1.12e-28	-	-	-	K	-	-	-	transcriptional regulator
PNFEGDNE_01862	2.64e-98	-	-	-	S	-	-	-	intracellular protease amidase
PNFEGDNE_01863	2.73e-167	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
PNFEGDNE_01864	3.48e-143	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PNFEGDNE_01865	2.06e-291	treC	-	-	G	-	-	-	Psort location Cytoplasmic, score
PNFEGDNE_01866	5.79e-51	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PNFEGDNE_01867	1.68e-157	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PNFEGDNE_01868	7.67e-139	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
PNFEGDNE_01869	1.32e-84	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
PNFEGDNE_01870	6.73e-102	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PNFEGDNE_01871	5.9e-178	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PNFEGDNE_01872	3.98e-253	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PNFEGDNE_01873	3.59e-149	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PNFEGDNE_01874	1.09e-243	-	-	-	C	-	-	-	FMN_bind
PNFEGDNE_01875	3.2e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
PNFEGDNE_01876	1.21e-201	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PNFEGDNE_01877	7.26e-250	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PNFEGDNE_01878	1.14e-92	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PNFEGDNE_01879	6.41e-167	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
PNFEGDNE_01880	1.39e-126	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PNFEGDNE_01881	1.88e-76	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PNFEGDNE_01882	2.62e-05	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PNFEGDNE_01883	5.3e-12	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
PNFEGDNE_01884	9.91e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
PNFEGDNE_01885	7.06e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PNFEGDNE_01887	4.09e-291	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PNFEGDNE_01888	5.64e-81	-	-	-	C	-	-	-	FMN binding
PNFEGDNE_01889	2.63e-262	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PNFEGDNE_01890	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PNFEGDNE_01891	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PNFEGDNE_01907	3.46e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
PNFEGDNE_01908	1.04e-85	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
PNFEGDNE_01910	1.77e-67	-	-	-	K	-	-	-	LysR substrate binding domain
PNFEGDNE_01911	1.36e-151	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PNFEGDNE_01912	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
PNFEGDNE_01913	1.54e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PNFEGDNE_01914	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PNFEGDNE_01915	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
PNFEGDNE_01919	3.14e-50	blpT	-	-	-	-	-	-	-
PNFEGDNE_01920	1.94e-18	-	-	-	-	-	-	-	-
PNFEGDNE_01922	1.9e-235	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PNFEGDNE_01923	2.3e-103	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
PNFEGDNE_01924	2.27e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
PNFEGDNE_01925	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PNFEGDNE_01926	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PNFEGDNE_01927	4.48e-95	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PNFEGDNE_01928	1.02e-259	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PNFEGDNE_01929	2.19e-191	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PNFEGDNE_01930	1.74e-80	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PNFEGDNE_01931	4.37e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
PNFEGDNE_01932	2.9e-114	nanK	-	-	GK	-	-	-	ROK family
PNFEGDNE_01933	4.39e-162	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PNFEGDNE_01934	4.52e-118	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PNFEGDNE_01935	2.33e-95	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PNFEGDNE_01936	1.31e-45	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
PNFEGDNE_01937	5.07e-270	potE	-	-	E	-	-	-	Amino Acid
PNFEGDNE_01938	1.16e-08	-	-	-	-	-	-	-	-
PNFEGDNE_01939	5.44e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PNFEGDNE_01940	3.32e-288	fusA1	-	-	J	-	-	-	elongation factor G
PNFEGDNE_01941	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PNFEGDNE_01942	1.38e-113	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PNFEGDNE_01943	7.62e-217	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
PNFEGDNE_01944	8.33e-151	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
PNFEGDNE_01945	1.46e-233	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PNFEGDNE_01946	1.36e-47	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PNFEGDNE_01947	2.62e-52	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PNFEGDNE_01948	9.75e-78	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
PNFEGDNE_01949	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PNFEGDNE_01951	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNFEGDNE_01952	2.53e-142	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNFEGDNE_01953	1.04e-99	-	-	-	S	-	-	-	Fic/DOC family
PNFEGDNE_01954	1.9e-161	-	-	-	L	-	-	-	PLD-like domain
PNFEGDNE_01955	1.56e-46	-	-	-	L	-	-	-	PLD-like domain
PNFEGDNE_01958	3.24e-142	-	-	-	L	-	-	-	Initiator Replication protein
PNFEGDNE_01959	3.46e-46	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
PNFEGDNE_01960	3.57e-157	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PNFEGDNE_01961	5.35e-43	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PNFEGDNE_01962	2.97e-112	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	.Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
PNFEGDNE_01963	3.71e-21	bglG	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
PNFEGDNE_01964	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
PNFEGDNE_01966	3.14e-47	-	-	-	-	-	-	-	-
PNFEGDNE_01967	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PNFEGDNE_01968	2.91e-53	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
PNFEGDNE_01969	2.78e-23	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PNFEGDNE_01971	8.82e-138	XK27_09655	-	-	S	-	-	-	Virulence protein RhuM family
PNFEGDNE_01972	3.58e-158	yvgN	-	-	C	-	-	-	Aldo keto reductase
PNFEGDNE_01973	3.87e-131	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
PNFEGDNE_01974	1.71e-80	-	-	-	S	-	-	-	Sulphur transport
PNFEGDNE_01975	1.15e-23	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
PNFEGDNE_01976	4.79e-148	-	-	-	P	-	-	-	Rhodanese Homology Domain
PNFEGDNE_01978	1.68e-291	prdA	1.21.4.1	-	EJ	ko:K10793	ko00330,map00330	ko00000,ko00001,ko01000	Glycine/sarcosine/betaine reductase component B subunits
PNFEGDNE_01979	1.57e-34	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PNFEGDNE_01980	8.02e-85	prdB	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a premature stop
PNFEGDNE_01981	2.69e-42	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a premature stop
PNFEGDNE_01982	1.19e-91	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
PNFEGDNE_01983	6.97e-87	-	-	-	EJ	-	-	-	Glycine/sarcosine/betaine reductase component B subunits
PNFEGDNE_01984	3.01e-182	-	5.1.1.4	-	E	ko:K01777	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Proline racemase
PNFEGDNE_01985	5.57e-123	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
PNFEGDNE_01986	1.53e-280	-	-	-	E	-	-	-	amino acid
PNFEGDNE_01987	2.05e-61	yedF	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
PNFEGDNE_01989	1.2e-169	selB	-	-	J	ko:K03833	-	ko00000,ko03012	Elongation factor SelB, winged helix
PNFEGDNE_01990	1.37e-137	-	-	-	E	-	-	-	Serine hydroxymethyltransferase
PNFEGDNE_01991	1.12e-142	selA	2.9.1.1	-	J	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
PNFEGDNE_01992	3.75e-38	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PNFEGDNE_01993	3.12e-235	-	-	-	C	-	-	-	RnfC Barrel sandwich hybrid domain
PNFEGDNE_01994	2.28e-124	selD	2.7.9.3	-	E	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	AIR synthase related protein, C-terminal domain
PNFEGDNE_01995	1.31e-187	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
PNFEGDNE_01996	4.23e-38	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
PNFEGDNE_01997	2.8e-15	-	-	-	GKT	-	-	-	COG3711 Transcriptional antiterminator
PNFEGDNE_01998	5.14e-75	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
PNFEGDNE_01999	4.7e-231	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
PNFEGDNE_02000	5.17e-63	-	-	-	S	-	-	-	Membrane
PNFEGDNE_02001	9e-95	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PNFEGDNE_02002	4.7e-239	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
PNFEGDNE_02003	1.26e-272	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PNFEGDNE_02004	8.21e-53	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
PNFEGDNE_02005	2.46e-277	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
PNFEGDNE_02006	6.46e-141	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PNFEGDNE_02008	7.06e-27	-	-	-	S	-	-	-	YjcQ protein
PNFEGDNE_02009	3.81e-134	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNFEGDNE_02011	3.1e-64	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PNFEGDNE_02012	3.85e-36	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PNFEGDNE_02013	1.17e-103	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
PNFEGDNE_02014	8.69e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
PNFEGDNE_02015	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
PNFEGDNE_02016	0.0	-	-	-	V	-	-	-	restriction
PNFEGDNE_02017	0.0	-	-	-	S	-	-	-	TIGR02687 family
PNFEGDNE_02018	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
PNFEGDNE_02019	1.38e-55	-	-	-	-	-	-	-	-
PNFEGDNE_02020	1.34e-48	-	-	-	-	-	-	-	-
PNFEGDNE_02023	1.28e-14	-	-	-	-	-	-	-	-
PNFEGDNE_02024	3.11e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
PNFEGDNE_02025	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
PNFEGDNE_02029	5.5e-215	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
PNFEGDNE_02030	2.73e-185	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
PNFEGDNE_02031	1.83e-146	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PNFEGDNE_02032	2.29e-75	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PNFEGDNE_02033	1.87e-101	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
PNFEGDNE_02034	4.83e-60	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PNFEGDNE_02036	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PNFEGDNE_02037	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PNFEGDNE_02038	1.22e-66	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
PNFEGDNE_02039	3.32e-75	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PNFEGDNE_02040	2.85e-197	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PNFEGDNE_02041	8.45e-120	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
PNFEGDNE_02042	8.3e-160	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
PNFEGDNE_02043	1.54e-55	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PNFEGDNE_02044	2.64e-26	tnp	-	-	-	ko:K07498	-	ko00000	-
PNFEGDNE_02045	1.32e-33	-	-	-	L	ko:K07498	-	ko00000	Transposase
PNFEGDNE_02046	3.43e-45	-	-	-	P	-	-	-	Heavy-metal-associated domain
PNFEGDNE_02047	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
PNFEGDNE_02048	1.2e-28	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
PNFEGDNE_02049	6.56e-52	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
PNFEGDNE_02050	3.04e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
PNFEGDNE_02051	7.6e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PNFEGDNE_02052	8.06e-122	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PNFEGDNE_02053	2.63e-89	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
PNFEGDNE_02054	7.4e-177	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
PNFEGDNE_02055	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PNFEGDNE_02056	2.95e-271	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PNFEGDNE_02057	5.13e-176	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PNFEGDNE_02058	4.79e-89	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PNFEGDNE_02059	4.43e-181	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
PNFEGDNE_02063	3.79e-113	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
PNFEGDNE_02064	1.06e-13	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PNFEGDNE_02065	2.12e-48	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PNFEGDNE_02066	2.37e-97	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
PNFEGDNE_02067	6.11e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PNFEGDNE_02068	1.94e-67	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PNFEGDNE_02069	8.46e-101	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PNFEGDNE_02070	1.15e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PNFEGDNE_02071	5e-100	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PNFEGDNE_02072	1.42e-34	-	-	-	-	-	-	-	-
PNFEGDNE_02073	3.76e-18	-	-	-	-	-	-	-	-
PNFEGDNE_02074	2.15e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
PNFEGDNE_02075	5.49e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PNFEGDNE_02076	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
PNFEGDNE_02077	6.68e-64	-	-	-	S	-	-	-	VIT family
PNFEGDNE_02078	1.66e-72	-	-	-	L	ko:K07487	-	ko00000	Transposase DDE domain
PNFEGDNE_02079	9.19e-304	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PNFEGDNE_02080	1.9e-52	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PNFEGDNE_02081	5.43e-182	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PNFEGDNE_02082	4.96e-178	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PNFEGDNE_02083	1.5e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PNFEGDNE_02084	3.47e-278	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PNFEGDNE_02085	8.52e-177	-	-	-	P	-	-	-	Voltage gated chloride channel
PNFEGDNE_02086	5.44e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNFEGDNE_02087	5.44e-173	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PNFEGDNE_02088	9.61e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PNFEGDNE_02089	1.01e-83	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
PNFEGDNE_02090	1.28e-46	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PNFEGDNE_02091	8.56e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
PNFEGDNE_02092	4.75e-107	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
PNFEGDNE_02093	9.94e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
PNFEGDNE_02094	1.41e-93	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
PNFEGDNE_02095	8.3e-142	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
PNFEGDNE_02096	3.46e-34	-	-	-	M	-	-	-	by MetaGeneAnnotator
PNFEGDNE_02097	2e-46	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PNFEGDNE_02099	1.04e-07	-	-	-	S	-	-	-	Phage minor structural protein GP20
PNFEGDNE_02101	1.01e-34	-	-	-	S	-	-	-	Phage Mu protein F like protein
PNFEGDNE_02102	2.16e-125	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
PNFEGDNE_02103	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PNFEGDNE_02105	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
PNFEGDNE_02106	7.43e-91	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PNFEGDNE_02110	8.17e-104	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PNFEGDNE_02111	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PNFEGDNE_02113	1.66e-63	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PNFEGDNE_02114	1.16e-61	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PNFEGDNE_02118	2.03e-242	repA	-	-	S	-	-	-	Replication initiator protein A
PNFEGDNE_02119	5.03e-35	-	-	-	-	-	-	-	-
PNFEGDNE_02120	2.49e-178	-	-	-	S	-	-	-	Fic/DOC family
PNFEGDNE_02121	2.83e-58	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
PNFEGDNE_02122	3.96e-37	-	-	-	-	-	-	-	-
PNFEGDNE_02123	1.58e-38	-	-	-	S	-	-	-	protein conserved in bacteria
PNFEGDNE_02124	2.13e-93	-	-	-	S	-	-	-	protein conserved in bacteria
PNFEGDNE_02125	2.09e-55	-	-	-	-	-	-	-	-
PNFEGDNE_02126	1.29e-32	-	-	-	-	-	-	-	-
PNFEGDNE_02127	0.0	-	-	-	L	-	-	-	MobA MobL family protein
PNFEGDNE_02128	1.94e-40	-	-	-	L	-	-	-	MULE transposase domain
PNFEGDNE_02130	5.57e-80	-	-	-	V	-	-	-	HNH endonuclease
PNFEGDNE_02131	8.38e-169	-	-	-	F	-	-	-	NUDIX domain
PNFEGDNE_02132	2.28e-118	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PNFEGDNE_02133	5.19e-195	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PNFEGDNE_02134	2.13e-134	pncA	-	-	Q	-	-	-	Isochorismatase family
PNFEGDNE_02136	6.8e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNFEGDNE_02137	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PNFEGDNE_02138	3.17e-51	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PNFEGDNE_02139	3.97e-136	-	-	-	-	-	-	-	-
PNFEGDNE_02140	1.41e-129	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PNFEGDNE_02141	2.06e-192	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PNFEGDNE_02142	2.42e-200	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PNFEGDNE_02143	4.2e-124	-	-	-	M	-	-	-	Cna protein B-type domain
PNFEGDNE_02144	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
PNFEGDNE_02145	2.44e-104	-	-	-	-	-	-	-	-
PNFEGDNE_02146	6.74e-17	-	-	-	-	-	-	-	-
PNFEGDNE_02147	2.57e-60	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PNFEGDNE_02148	2.2e-202	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PNFEGDNE_02149	7.96e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PNFEGDNE_02150	3.13e-35	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
PNFEGDNE_02151	4.18e-75	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PNFEGDNE_02152	4.86e-94	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
PNFEGDNE_02153	1.94e-40	-	-	-	L	-	-	-	MULE transposase domain
PNFEGDNE_02154	8.46e-65	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PNFEGDNE_02155	1.74e-74	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
PNFEGDNE_02156	6.36e-190	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
PNFEGDNE_02157	4.18e-46	-	-	-	-	-	-	-	-